AP Biology Catalyst Which of the following choices lists the Organization of Life in order of...

17
AP Biology Catalyst Which of the following choices lists the Organization of Life in order of increasing complexity? Organism Organs Organ Systems Cells Tissues Organs Cells Tissues Organ Systems Organism Cells Tissues Organs Organ Systems Organisms Tissues Organs Organ Systems Cells Organism 2. What is the main difference between prokaryotes and Eukaryotes? 3. Where do you find the DNA in a Eukaryote? A prokaryote?

Transcript of AP Biology Catalyst Which of the following choices lists the Organization of Life in order of...

AP Biology

Catalyst Which of the following choices lists the Organization of Life in order of

increasing complexity? Organism Organs Organ Systems Cells Tissues Organs Cells Tissues Organ Systems Organism Cells Tissues Organs Organ Systems Organisms Tissues Organs Organ Systems Cells Organism

2. What is the main difference between prokaryotes and Eukaryotes?

3. Where do you find the DNA in a Eukaryote? A prokaryote?

AP Biology

The Cell Membrane (Plama membrane)

AP Biology

Overview Cell membrane separates living cell from

nonliving surroundings thin barrier = 8nm thick

Controls traffic in & out of the cell selectively permeable allows some substances to cross more easily

than others hydrophobic vs hydrophilic

Made of phospholipids, proteins & other macromolecules

AP Biology

Phospholipids

Fatty acid

Phosphate

Fatty acid tails hydrophobic

Phosphate group head hydrophilic

Arranged as a bilayer- what is a bilayer?

Aaaah, one of those

structure–functionexamples

AP Biology

Phospholipids are the major structural component of

membranes.Heads are made of

phosphate group and alcohol

Tails are nonpolar and made of carbon and

hydrogen.

AP Biology

Phospholipid bilayer

polarhydrophilic

heads

nonpolarhydrophobic

tails

polarhydrophilic

heads

AP Biology

More than lipids… In 1972, S.J. Singer & G. Nicolson

proposed that membrane proteins are inserted into the phospholipid bilayer

It’s like a fluid…It’s like a mosaic…

It’s the Fluid Mosaic Model!

AP Biology

Membrane is a collage of proteins & other molecules embedded in the fluid matrix of the lipid bilayer

Extracellular fluid

Cholesterol

Cytoplasm

Glycolipid

Transmembraneproteins

Filaments ofcytoskeleton

Peripheralprotein

Glycoprotein

Phospholipids

AP Biology

Membrane fat composition varies Fat composition affects flexibility

membrane must be fluid & flexible about as fluid as thick salad oil

% unsaturated fatty acids in phospholipids keep membrane less viscous cold-adapted organisms, like winter wheat

increase % in autumn

cholesterol in membrane

AP Biology

Cholesterol What does cholesterol do?

Helps maintain the integrity of the plasma membrane.

Helps maintains the fluidity of the membrane- helps with extremes

Helps hold integral proteins into the membrane.

AP Biology

Membrane Proteins Proteins determine membrane’s specific functions

cell membrane & organelle membranes each have unique collections of proteins

Membrane proteins: peripheral proteins

loosely bound to surface of membrane cell surface identity marker (antigens)

integral proteins penetrate lipid bilayer, usually across whole membrane transmembrane protein transport proteins

channels, permeases (pumps)

AP Biology

AP Biology

What do membrane proteins do? Plasma membrane proteins function in several

different ways. selective transport of certain substances across

the phospholipid bilayer, either acting as channels or active transport molecules.

receptors, which bind information-providing molecules, such as hormones, and transmit signals

Membrane proteins may also exhibit enzymatic activity, catalyzing various reactions related to the plasma membrane.

AP Biology

Many Functions of Membrane Proteins

Outside

Plasmamembrane

InsideTransporter Cell surface

receptorEnzymeactivity

Cell surface identity marker

Attachment to thecytoskeleton

Cell adhesion

AP Biology 2007-2008

Why areproteins the perfect

molecule to build structures in the cell membrane?

AP Biology

Membrane carbohydrates Play a key role in cell-cell recognition

ability of a cell to distinguish one cell from another antigens

important in organ & tissue development

basis for rejection of foreign cells by immune system

AP Biology 2007-2008

Movement across the Cell Membrane