5 Levels of Organization. Cells Tissues Organs Organ Systems Organism.
AP Biology Catalyst Which of the following choices lists the Organization of Life in order of...
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Transcript of AP Biology Catalyst Which of the following choices lists the Organization of Life in order of...
AP Biology
Catalyst Which of the following choices lists the Organization of Life in order of
increasing complexity? Organism Organs Organ Systems Cells Tissues Organs Cells Tissues Organ Systems Organism Cells Tissues Organs Organ Systems Organisms Tissues Organs Organ Systems Cells Organism
2. What is the main difference between prokaryotes and Eukaryotes?
3. Where do you find the DNA in a Eukaryote? A prokaryote?
AP Biology
Overview Cell membrane separates living cell from
nonliving surroundings thin barrier = 8nm thick
Controls traffic in & out of the cell selectively permeable allows some substances to cross more easily
than others hydrophobic vs hydrophilic
Made of phospholipids, proteins & other macromolecules
AP Biology
Phospholipids
Fatty acid
Phosphate
Fatty acid tails hydrophobic
Phosphate group head hydrophilic
Arranged as a bilayer- what is a bilayer?
Aaaah, one of those
structure–functionexamples
AP Biology
Phospholipids are the major structural component of
membranes.Heads are made of
phosphate group and alcohol
Tails are nonpolar and made of carbon and
hydrogen.
AP Biology
Phospholipid bilayer
polarhydrophilic
heads
nonpolarhydrophobic
tails
polarhydrophilic
heads
AP Biology
More than lipids… In 1972, S.J. Singer & G. Nicolson
proposed that membrane proteins are inserted into the phospholipid bilayer
It’s like a fluid…It’s like a mosaic…
It’s the Fluid Mosaic Model!
AP Biology
Membrane is a collage of proteins & other molecules embedded in the fluid matrix of the lipid bilayer
Extracellular fluid
Cholesterol
Cytoplasm
Glycolipid
Transmembraneproteins
Filaments ofcytoskeleton
Peripheralprotein
Glycoprotein
Phospholipids
AP Biology
Membrane fat composition varies Fat composition affects flexibility
membrane must be fluid & flexible about as fluid as thick salad oil
% unsaturated fatty acids in phospholipids keep membrane less viscous cold-adapted organisms, like winter wheat
increase % in autumn
cholesterol in membrane
AP Biology
Cholesterol What does cholesterol do?
Helps maintain the integrity of the plasma membrane.
Helps maintains the fluidity of the membrane- helps with extremes
Helps hold integral proteins into the membrane.
AP Biology
Membrane Proteins Proteins determine membrane’s specific functions
cell membrane & organelle membranes each have unique collections of proteins
Membrane proteins: peripheral proteins
loosely bound to surface of membrane cell surface identity marker (antigens)
integral proteins penetrate lipid bilayer, usually across whole membrane transmembrane protein transport proteins
channels, permeases (pumps)
AP Biology
What do membrane proteins do? Plasma membrane proteins function in several
different ways. selective transport of certain substances across
the phospholipid bilayer, either acting as channels or active transport molecules.
receptors, which bind information-providing molecules, such as hormones, and transmit signals
Membrane proteins may also exhibit enzymatic activity, catalyzing various reactions related to the plasma membrane.
AP Biology
Many Functions of Membrane Proteins
Outside
Plasmamembrane
InsideTransporter Cell surface
receptorEnzymeactivity
Cell surface identity marker
Attachment to thecytoskeleton
Cell adhesion
AP Biology
Membrane carbohydrates Play a key role in cell-cell recognition
ability of a cell to distinguish one cell from another antigens
important in organ & tissue development
basis for rejection of foreign cells by immune system