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    Anxiety Disorders in Children andAdolescents

    Sucheta Connolly M.D.

    Director, UIC Pediatric Stress and AnxietyDisorders Clinic

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    Normal Fears and Worries

    Infants: fear of loud noises, strangers

    Toddlers: fear of the dark, monsters, separationfrom parents

    School-age: physical injury, storms, school

    Teenagers: social evaluation and school

    performance

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    Common Stressors

    Divorce

    Family move or friend moves away

    oss of pet !reak up with girlfriend"#oyfriend

    $oor performance at school"test

    Death of relative Transition to middle school"high school

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    Signs and Symptoms of

    Stress and Anxiety in Youth %ecurrent fears and worries

    Difficulty falling asleep or nightmares

    &ard to rela' Difficulty separating from parents

    Scared a#out going to school

    Irrita#ility, crying, tantrums (ncomforta#le in social situations at school,

    restaurants, parties

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    Anxiety Disorders in Children

    and Adolescents )ery common: *-+ of youth have at least one

    an'iety disorder %uns in families ./enetics and modeling0

    1o-occur with 2D&D in children, and depression and

    su#stance a#use in teens 1an persist into adulthood

    Treatments are availa#le and effective:

    1ognitive-#ehavioral therapy and medication

    3arly identification and treatment can reduce severityand impairment in social and academic functioning

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    Separation Anxiety Disorder

    Excessive fear and distress when separated

    fro parents!priary care"ivers or hoe

    4orry a#out parents5 health and safety

    Difficulty sleeping without parents

    Difficulty alone in another part of the house

    1omplain of stomachaches and headaches

    6ay refuse to go to school or playdates

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    Generalized Anxiety Disorder

    Excessive, chronic worry related to school,

    a#in" friends, health and safety of self and

    faily, future events, local and world events

    2lso has at least one of these symptoms:

    motor"muscle tension, fatigue, difficulty sleeping,

    irrita#ility, poor concentration

    7ften perfectionists

    2n'iety may #e significant, #ut not apparent to others

    $hysical complaints are common

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    GAD: Additional features

    3'cessive self-consciousness, fre8uentreassurance-seeking , worry a#outnegative conse8uences

    $erfectionistic, e'cessively critical ofthemselves, persistent worries

    1ommon somatic complaints: /Idistress, headaches, fre8uent urination,sweating, tremor

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    Social ho!ia

    "Social Anxiety Disorder# Excessive fear or discofort in social orperforance situations

    3'treme fear of negative evaluation #y others

    4orry a#out doing something e$arrassin" in

    settings such as classrooms, restaurants, sports,

    musical or speech performance

    Difficulty participating in class, working in groups,

    attending gym, using pu#lic rest rooms, eating in

    front of others, starting conversations, making new

    friends, talking on the phone, having picture taken

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    Social ho!ia

    1ommonly feared social situations:

    $u#lic performances .reading aloud in front ofclass, music"athletic performances0,

    7rdinary social situations .starting or joiningconversations, speaking to adults0

    7rdering food at restaurants, attending dancesand parties, takings tests, working or playingwith other children, asking teacher for help.!eidel et al9 +0

    Diminished social skills, longer speechlatencies, fewer or no friends, limitedactivities, school refusal .!eidel et al9 +0

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    Selecti$e %utism

    Una$le to spea# in certain situations %school&despite a$le to spea# in other settin"s %hoe&

    Difficulty speaking, laughing, reading aloud, singing

    aloud in front of people outside the family or their ;safe

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    Selecti$e %utism

    Transient mutism during transitionalperiods: first month of school or moveto a new home

    %elationship #etween S6 and Social

    $ho#ia2ssociated features: e'cessive

    shyness, fear of social em#arrassment,

    social isolation, clinging, compulsivetraits, negativism, temper tantrums,controlling or oppositional #ehavior,particularly at home

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    Specific ho!ia

    Excessive fear of a particular o$'ect or situation 6ay avoid the feared o#ject or situation

    If a fear is severe enough to impair a child5s

    functioning, then it is a pho#ia

    Coon pho$ias: animals"insects, heights,

    storms, water, darkness, #lood, shots, traveling #y

    car"#us"plane, elevators, loud noises, costumed

    characters, doctor or dentists, vomiting, choking,

    catching a disease

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    Specific ho!ia

    2n'iety may #e e'pressed through crying,

    tantrums, free

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    anic Disorder

    (ecurrent panic attac#s or intense fear:

    racing heart, sweating, shaking, difficulty

    #reathing, nausea, di

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    anic Disorder

    Full panic disorder #est documented in

    adolescents

    $anic attacks in younger children are

    usually cued or triggered #y specific

    event of stressor, with out-of-#lueattacks rare

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    Differentiating the Specific

    Childhood Anxiety Disorders+AD and Social pho$ia

    4orries of /2D is pervasive, and not limited to

    specific o#ject .Specific pho#ia0 or social situations

    .Social pho#ia0

    /2D an'iety is persistent, Social pho#ia an'iety

    dissipates upon avoidance or escape of social

    situation

    4orries a#out 8uality of relationship with /2Dversus em#arrassment and social evaluation fears

    with Social pho#ia

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    Differentiating Anxiety

    Disorders: Clinical oints 1ued panic attacks can occur with any of the

    an'iety disorders in youth, and common among

    adolescents

    Irrita#ility and angry out#ursts may #e

    misunderstood as oppositionality or diso#edience

    Tantrums, crying, stomachaches, headaches

    common in children with an'iety 1hildren .versus adults0 may not see fear as

    unreasona#le

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    &!sessi$e Compulsi$e Disorder

    $sessions- Scary, $ad, unwanted or upsettin"thou"hts, ipulses, or pictures that #eep

    coin" $ac# over and over

    3'amples of o#sessions: 2ggressive o#sessions,

    contamination, dou#ting, nonsensical thoughts,hoarding"saving, religious, symmetry"e'actness,

    violent thoughts"images, thoughts a#out se',

    thoughts of death"dying

    1hild tries to ignore or suppress the thoughts,impulses, or images

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    &!sessi$e Compulsi$e Disorder Copulsions- repetitive $ehaviors or ental acts

    %prayin", countin", repeatin" words!nu$ers silently&

    that the child feels copelled to do in order to stop

    discofort!anxiety of o$sessions

    3'amples: 1leaning"washing, checking, counting,

    hoarding"collecting, repeating words"num#ers silently,

    ordering"arranging, praying, seek reassurance,touching"tapping, ;tell on yourself=, ;just right=

    $ersistent o#sessions, compulsions, or #oth that occupy

    more than + hour each day

    %epetitive and difficult to control

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    ostulated 'nfectious(Autoimmune

    )tiology $ediatric 2utoimmune >europsychiatric

    Disorders 2ssociated with Strep9 ?

    $2>D2S $ediatric Infection-Triggered

    2utoimmune >europsychiatric

    Disorders ? $IT2>Ds

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    'nfection "group A !eta*hemolytic strep+#

    'mmune ,esponse

    "anti!odies produced#

    ,e$ersi!le "-# .esion of /asal Ganglia

    &CD and(or tics

    '0ANDs "ANDAS#

    athophysiology

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    Treatment Planning forChildhood Anxiety Disorders

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    Treatment Planning

    A"e, severity, ipairent, and coor$idity Mild severity: 1onsider 1!T first

    Modsevere: 6edications considered for

    acute relief of an'iety, partial response from

    other treatment, comor#id disorders that may#enefit from meds and multimodal approach

    Severe- 1om#ination intensive treatments

    with 1!T and medications may #e necessary 7lder youth, depression, and social

    withdrawal often need intensive treatment

    Involve child and family in treatment planning

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    0reatment lanning Continued

    If Parental Anxiety Disorders Present-

    Teach parents an'iety reduction skills

    1onsider if independent treatment of parental an'iety

    disorders needed .meds, therapy0

    1onsider additional parental involvement with younger

    child

    7lder youth - depression, social withdrawal, su#stance

    a#use often need intensive focus

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    Child*Adolescent Anxiety

    %ultimodal Study "CA%S#"Wal1up2 et al+: N )ng 3 %ed2 4556# @** children .A-+Ay0:S2D, /2D, Social $ho#ia +@ sessions of 1!T, sertraline to Bmg"day,

    com#ination 1!T and sert, or +B weeks of

    place#o9

    )ery much or much improved on 1/I-

    Improvement scale: *+ com#ination, C

    1!T, sertraline, B@ place#o !oth 1!T and sertraline reduced severity of

    an'iety in children with an'iety disorders,

    com#ination had superior response rate

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    CA%S Study

    >o increased fre8uency of physical,psychiatric, or harm-related adverse events insertraline vs9 place#o groups

    Suicidal or homicidal ideation was uncommon,

    no child attempted suicide Eouth with 2D&D were included9 Eouth with

    depression or $DD were e'cluded 1om#ination therapy offers #est chance for

    positive outcome: consider family preference,cost, treatment availa#ility9

    $lace#o for sertraline only group, not forsertraline plus 1!T group9

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    C/0 and /eyond

    Standard 1!TSocial skills training2ssertiveness skillsSelf-esteem4orking with parents and schools

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    thin1

    feel

    C/0 %odel of Anxiety:

    Anxiety7s 0hree Components

    1ognitive:

    $hysiological:

    !ehavioral: do

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    Social Phobia

    Fears of #eing the focus ofFears of #eing the focus of

    attention and em#arrassing selfattention and em#arrassing self

    Increased heart rate, shaking,Increased heart rate, shaking,sweating, hyperventilation,sweating, hyperventilation,

    di

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    CBT Principles for Anxiety.2l#ano Gendall, BB0

    Psychoeducation .a#out an'iety and 1!T0 Soatic ana"eent s#ills trainin"

    .self-monitor an'iety and learn muscle

    rela'ation, diaphragmatic #reathing, imagery0

    Co"nitive awareness and restructurin"

    .identify and challenge negative thoughts and

    e'pectationsH positive self-talkH 0

    Exposure ethods.imaginal and livee'posures with gradual desensiti

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    0reatment of Anxiety Disorders

    in Children and Adolescents $sychoeducation with the child and parents a#out the

    illness and principles of 1!T

    $arent training to esta#lish daily structure,

    e'pectations, positive reinforcement, monitoring of

    symptoms and progress

    Involve parents in treatment, especially for children

    and when parental an'iety present

    1onsider independent treatment of an'iety disorders

    in parents

    1oordinate treatment with school

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    C/0 for Anxiety Disorders in

    Children and Adolescents 1onsider age and developmental stage of

    child

    For younger children using positivereinforcement chart and fre8uent rewards for

    efforts is very important9 3'posures increase

    an'iety and children need motivation to try9

    For younger children use of pictures,cartoons, puppets, and toys to supplement

    standard 1!T is helpful9

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    Establish Target Symptoms

    /earn to identify feelin"s in self 0 others.feelings #arometer0

    Esta$lish level of distress

    .feelings thermometer0

    Develop /adder of stiuli or tri""ers.situations, o#jects, cues, sensations0 withinprimary diagnosis

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    Cognitive estr!ct!ring

    1hallenge >egative Thoughts

    1hallenge >egative 3'pectations

    $ositive Self-Talk

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    Cognitive Distortions

    1outh with anxiety disorders- 2ssume #ad things will happen

    !iased attention to threatening words and

    criticism

    Interpret am#iguous situations as threatening

    6ore negative self-talk

    (nderestimate their strengths

    2ssume they cannot handle stressful

    situations

    1atastrophic thinking: 2ssume the worst

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    Cognitive estr!ct!ring" #oals

    Identify negative thoughts that predict #adthings will happen- thinking traps

    3valuate negative thoughts to determine ifthey make sense

    (se realistic positive self-talk to argue withnegative thoughts and #oss them #ack9

    %eplace thinking traps with coping thoughts

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    Cognitive estr!ct!ring

    (se similar strategies to come up with

    alternatives to negative thoughts or

    misperceptions that result in angry feelings

    !oss #ack aggressive urges

    $ractice alternatives to assuming someone will

    violate you, hurt you, critici

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    )8&S9,)S

    Imaginal 3'posures

    %ole-playsive 3'posures

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    Expos!res /raded so child can e'perience success and

    #uild confidence .not flooding0

    3'plain that discomfort is part of e'posure

    !egin with rela'ation e'ercise to start with

    an'iety at low level %eview coping strategies

    3sta#lish reward system

    6ove from easiest to most challenging itemson Fear adder

    Therapist should avoid too much reassurance

    during e'posure

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    #raded $maginal Expos!re 1hild imagines item or situation from Fear

    adder"&ierarchy in detail !egin with easy items to more challenging

    1hild notes intensity on Fear Thermometer

    !ring an'iety to B or #elow #efore ne't item 2sk: Did anything terri#le happen

    $raise often9 %eward for efforts successes

    Incorporate rela'ation and self-talk learned toreduce an'iety

    2djust fre8uency, intensity of sessions #ased

    on success

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    &ther Applications for )xposures

    Imaginal e'posure and role-plays can #e used

    for a range of #ehaviors

    This may allow child to identify feelings andthoughts that pop out in certain situations that

    make them angry, sad, scared

    /ives opportunity to practice new coping

    strategies and #ehaviors !e sure to praise for just trying e'posures

    .imaginary or real0

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    0reatment for Social ho!ia and

    anic Disorder Successful treatent of Social Pho$ia and Selective

    Mutisre8uires 1!T discussed and additional Social

    Skills Training

    2reatent of Panic Disorder 7ftenre8uires medications .SS%I5s, other antidepressants first-

    line0

    C32 for treatent of Panic disorderInteroceptive

    e'posure9 %ela'ation training, e'periencing physicalsymptoms in sessions, and overcoming sense of

    panic"doom9 Decrease avoidance increase control9

    Treatment for Selective M!tism

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    Treatment for Selective M!tism

    6ost children with S6 have Social pho#ia

    7ften need 1!T and social skills training

    Severity often warrants medication .SS%Is0

    6anagement team with parents and teacher monitoring child5s

    communication

    $ositive reinforcement for attempts on graded e'posure ladder

    Steps to speaking outside ;comfort

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    C/0 %odifications for S% Team approach with school involved regularly 1onversational visits )er#al intermediary .parent, friend, doll, toy

    puppet, recording device0 that makes morecomforta#le in trying to speak"communicate9

    Does not speak for child9 $ositive reinforcement fre8uently %einforce for nonver#al as well as ver#al

    responses

    S6 child can enlist strong negative responsein adults .la#eled as ;refusing to talk=0

    $arents and si#lings need to resist desire tospeak for child

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    School ef!sal

    Can $e variety of fears %separation,Can $e variety of fears %separation,social anxiety, test anxiety&social anxiety, test anxiety&

    4orry, tension, increased heart4orry, tension, increased heartrate, sha#in", sweatin"rate, sha#in", sweatin"

    5re6uent a$sence, tardiness, tears,5re6uent a$sence, tardiness, tears,

    tantrus, soatic coplaints,tantrus, soatic coplaints,

    visits to school nursevisits to school nurse

    thin1

    feel

    do

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    School ,efusal(School ho!ia This is a #ehavior cluster, not a diagnosis

    >eed to consider an'iety disorders and

    depression

    1onsider S2D, /2D, Social pho#ia

    >eed to rule out learning disa#ility that canlead to frustrations, poor performance, low

    self-esteem9 Increased risk for an'iety and

    depression9 Dysle'ia in young children9

    6ore common during transitions to a new

    school .pre-school, G/, middle school, high

    school0

    2ssist parents to reduce secondary gains

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    'nter$entions for School ,efusal

    %ule out D and language impairments

    If depression and an'iety present, 1!T and meds

    often needed

    2ssist parents and school staff to maintain

    patient in school9 2void home-#ound school (se li#rary or other area to calm or complete

    work part of day, #uild up in class time

    /raded e'posures to school situations

    2ctive ignoring of unreasona#le somatic

    complaints and reward regular attendance

    (se rela'ation and coping strategies to reduce

    an'iety at school9 1oaches at school too9

    h l f l ( dd

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    School ,efusal: Fear()xp .adder !e careful not to start e'posures close to

    vacations or holidays Initially work on preparing for going to school

    .depending on severity of fears0 with live andimaginal e'posures .driving past school,

    walking on school grounds, entering school0 Increasing time at school, not necessarily in

    classroom Start with most comforta#le setting"activity in

    classroom 4ork up to part of day and eventually full day Set up rewards for each step

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    0reatment of Youth ith &CD

    6ultimodal 2pproach

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    0reatment of Youth ith &CD

    1ognitive #ehavioral therapy .1!T0 in

    conjunction with medications .SS%I5s0

    3'posure and %esponse $revention .3"%$0

    Develop fear hierarchy, e'pose to pho#icstimuli and repress rituals or avoidance

    Family therapy can help decrease the parents5

    involvement in the child5s rituals and reinforcing

    #ehavior-#ased interventions

    Selective serotonin reuptake inhi#itors .SS%I5s0

    and 1lomipramine .T12 and SS%I0 are

    effective

    /oy ith &CD

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    /oy ith &CD

    ++ year #oy with 71D

    Intrusive se'ual thoughts"fears9 Dou#ting: %eassurance seeking ;Is this right

    2m I 7G= Fears of upsetting and harmingothers9

    (nderwear and pants have to fit ;just right=96other has to take in all waists9 >othing can#e loose fitting

    $erfectionism: 3rasing, rewriting drawings,work to make it ;right=9 Takes lots of time9

    1annot #e rushed to complete things9 Fears of upsetting /od and others:

    apologi

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    ;o ' ,an &CD &ff %y .and "3+

    %arch %D2 %;: %arch %anual#

    $sychoeducation with 71D as medical illnessand engage child and family in treatment Define 71D as the pro#lem: nasty nickname

    with plans to ;#oss #ack= 71D with therapist

    Story a#out 71D in child5s life: over timeauthors 71D out of his"her life

    6ap child5s 71D: o#sessions, compulsions,triggers, avoidance #ehaviors, conse8uences

    2n'iety management training 3'posure and response prevention .3"%$0

    using transition

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    C/0 for &CD: Adaptations for

    Young Child

    71D Story#ook .with farm animals and 71 Flea0 $ositive reinforcement program

    %eadjust hierarchy to achieve success with little steps

    in e'posures if needed9

    For young children can do imaginal e'posures usingpuppets, toys, cartoons to practicing ;#ossing #ack=

    71D

    1an adopt characteristics from superheroes that help

    child to defeat 71D 4atch 71D shrink in si

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    &CD )xposure(Fear .adder &olding doorkno# .e'posure0 and not washing

    hands .response prevention0 6oving items around in room .30 and not

    reorgani

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    Social Skills"

    Meeting and #reeting %e& People

    &aving a conversation: taking turns asking,telling, saying something and listening

    %ole-play situations with child or teenager

    $ractice with a friend and new children

    1oordinate with school staff .lunch group0

    Involve parents in sessions in younger child

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    Social Skills"

    %onverbal Comm!nication Importance of nonver#al communication and

    improving conversation skills

    $ersonal space

    3ye contact

    Speaking voice .volume0

    Involve parents in sessions for younger child

    A ti T i i

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    Assertiveness Training

    Many anxious children wor# hard to always

    please others and avoid conflicts 6ay fear something #ad will happen if they upset

    others or just discomfort

    6ore likely to #e #ullied

    1hild works on identifying own needs and negotiating

    these with children and adults

    %eview assertiveness strategies, role-play in session,

    then carry out e'posures

    1an use toys, puppets with young children to practice9

    Involve parents in sessions9

    (se rela'ation, coping strategies and fear ratings

    during role-play

    A ti T i i E l

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    Assertiveness Training" Example

    C y9o9 girl with /2D, S2D, Turner5s small stature9

    7ften picked up #y other children and girls fight over her not allowingher to play with other peers9 Sometimes children hold her down9 edto school pho#ia9 She fears other children will #e punished if shetells9

    $racticed using loud voice, mean face and posture in session9%ole-play with peers who are pushy and demand her to listen9

    $racticed turning on ;drama= when child annoying her and will notaccept no to get teacher5s attention

    1oordinated plan with school regarding practicing assertiveness andmonitoring of #ullying #y teacher in classroom and especially atrecess9

    $atient has #enefited greatly from 1!T, low dose SS%I9

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    Wor1ing ith arents and Schools

    Active I"norin"

    (ewards

    Involvin" Parents in C32 with child4or#in" with Schools

    5aily treatent

    'orking &ith Parents and

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    'orking &ith Parents and

    Teachers" Active $gnoring

    Active reinforceent of positive $ehaviors

    Active i"norin" of unwanted $ehaviorto

    e'tinguish .complaining, reassurance-seeking,

    crying, whining, somatic complaints0

    %ole-play with parents, discuss with teachers

    Temporary increase in pro#lem #ehavior, does not

    mean they should give in

    %educes children depending on adults rather thantrying new coping skills

    'orking &ith Parents and

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    'orking &ith Parents and

    Teachers" e&ards

    1hild chooses meaningful rewards Small, ine'pensive, or preferred activity %einforcement after desired #ehavior .trying

    not just successes0

    Short list of desired #ehaviors .fear ladder0 Su#stitute new #ehaviors as mastered Timely, consistent rewarding 1oordinate reward system #etween home

    school $ost in visi#le location at homeH teacher

    keeps in desk at school Child learns selfpraise over tie

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    $nvolving Parents in Treatment

    Parents with anxiety disorders can $enefitfro anxiety ana"eent s#ills!treatent

    and can iprove effectiveness of C32 in

    child

    $arents may #e overprotective, controlling, or

    facilitate avoidant responses

    $arents included in child5s treatment as

    ;coaches= to assist child in coping with current

    and future an'iety issues

    P $ l

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    Parent $nvolvement

    earn how to handle child5s an'iety earn graduated e'posure and how to use it

    6odify view of child as vulnera#le and in need

    of protection or control

    See child as resilient and capa#le of coping

    &elp parent to feel knowledgea#le and skilled

    enough to help the child cope with future

    challenges Involve all relevant caregivers to increase

    consistency of response to an'iety

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    Parent (Teacher) $nvolvement

    $arents .teachers0 can odel calmness and

    pro#lem-solving approaches

    Find middle ground: encourage the child toapproach feared situations and give child

    control over pace that is tolera#le

    /ive prompts, #ut resist need to ;rescue=

    Focus on small, positive steps, #uild courage,

    competence, and autonomy for child

    S h l $ t ti f A i t

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    School $nterventions for Anxiety

    School personnel who child can meet with

    regularly and #e availa#le to help child calm

    Discourage leaving school .fever or vomiting0

    3ncourage self-monitoring with Feelings

    Thermometer 1oping #ag availa#le if needed

    %einforce attempts to use rela'ation"coping

    skills as well as successful coping Desensiti

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    School $nterventions for

    St!dents &ith Anxiety

    Modified assi"nents Coprehension chec#s

    Identify adult at schooloutside classroom who can

    meet with child and engage in pro#lem-solving or

    an'iety management strategies School staff prompt child to use coping strategies prior

    to school triggers .tests, recess, starting assignment0

    2estin" in private, 8uiet place to reduce an'iety

    Educate teachera#out child5s an'iety and suggeststrategies to facilitate child5s coping .reframe0

    1hildren with an'iety disorders might 8ualify for a

    Section789 plan or special education if significant

    impact on school functioning .handout0

    *amily $nterventions

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    *amily $nterventions

    $arental emotional overinvolvement

    $arental criticism and control

    Family communication

    Impact of child an'iety on parent #ehavior

    Integrative models .Dadds %oth, B+0

    Interaction #etween attachment and

    parent-child learning process,

    #ehavioral and temperamental characteristics

    of child and parent

    1onsider impact on si#lings

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    Family 'nter$entions Canicholas BC0

    SS,' i Y Child

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    SS,'s in Young Children

    Start very low in young children and goslow to reduce side effects and increasetolerance to initial and temporary side

    effects Fluo'etine li8uid Bmg"ml can start at

    9-B9 mg"day Sertraline li8uid Bmg"+ml can start at

    B9-mg"day 6onitor for activation, #ehavioral

    disinhi#ition along with other side effects

    SS,'s for Selecti$e %utism

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    SS,'s for Selecti$e %utism +B week place#o- controlled study for Fluo'etine mean dose

    of 9Cmg"kg .!lack and (hde, +@0C children, ages C-+@, with S6 and Social $ho#ia

    Improved significantly on parent and teacher rating relative

    to place#o #ut still with S6 symptoms .with minimal side

    effects0

    7pen trial of B+ children ages to +@ with S6 supports

    Fluo'etine in graduated doses9 AC improved in an'iety and

    speech, inversely correlated with age .Dummit et al9, +A0

    Sertraline in children with S6 with low side effects, general

    #enefits .1arlson et al9, +0 onger trials with more individual dosing needed

    &ther Antidepressants

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    pTricyclic antidepressants .S2D, Social pho#ia0

    1onflicting results e'c 1lomipramine for 71D

    Cloipraine.T12 non-selective S%I0 1an augmentat low doses with SS%I9 %e8uires cardiac monitoring,

    3G/, #lood levels9 Side effects can #e significant:

    sedation, di

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    &ther %edications for Anxiety

    3uspirone./2D0

    >o pu#lished controlled studies92dverse side effects: lightheadedness,

    headache, dyspepsia9

    &igher peak plasma levels in children vsadolescents9 6ay #e tolerated at -Jmgin teens and -A9mg in children, twicedaily

    6ay #e an alternative to SS%Is for /2Din youth9 1ontrolled studies needed9

    6ay augment SS%Is9

    &ther %edications for Anxiety

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    &ther %edications for Anxiety!en

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    &ther %edications for Anxiety+uanfacine orClonidine

    >o controlled studies for an'iety disorders 1onsider w" SS%I when an'iety w" significant autonomic

    arousal and"or restlessness

    !aseline 3G/, !$ and pulse monitoring

    Severe re#ound hypertension with a#rupt discontinuation

    Tourette5s, 2D&D, Trichotillomania, other impulse-control

    disorders, !ipolar, $TSD

    33loc#ers

    1onsider for focused performance an'iety .>o trials in youth0

    %edications for Comor!idity

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    %edications for Comor!idity

    Depression: Impairment, SS%I, monitor suicidal

    risk, 1!T .Fluo'etine recommended0 AD=D: First choice stimulants and #eh t'9 If

    stimulants e'acer#ate insomnia or an'iety,

    2tamo'etine second line, also !uproprion and

    )enlafa'ine9 /uanfacine or clonidine .get 3G/0 forhyperactivity" impulsivity and sleep struggles9

    Alcohol a$use: 1aution against #en

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    0reatment of 0SD: %edicationsN Treat significant depression and anxiety

    N SS$+s "Antidepressants#

    For anxiety2 depression2 core symptoms

    N #!anfacine or Clonidine

    For hyperarousal2 impulsi$ity2 startleN Antipsychotics "such as ,isperidone#

    For dissociation2 !rief psychosis2 se$ere

    aggression"monitor A'%S or D'SC9S2 glucose2 eight#

    N Meds can red!ce severity of symptoms so

    child can engage in therapy and expos!res

    % di ti f C !id

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    %edications for Comor!id

    Autism Spectrum Disorders

    1onsider SS%I5s when o#sessive features,

    perseveration, rituals, an'iety, depression,

    irrita#ility prominent

    /uanfacine or 1lonidine may assist with

    impulsivity, e'plosiveness, restlessness

    7ther meds such as antipsychotics and mood

    sta#ili

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    Case )xample: %ary

    /2D, Depession, $hysical

    Trauma

    Case )xample: %ary

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    Case )xample: %ary +C y9o9 4F with recent #ack surgery due to lum#ar fracture that

    did not heal, chronic /2D9

    6ajor depression since surgery with high irrita#ility, decreased

    appetite, sleep distur#ance, anhedonia, hopelessness

    /2D never identified #efore with perfectionism regarding

    grades, sports, cannot rela', very goal-focused, over

    organi

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    y

    2gitated depression acutely increasing over B weeks

    and emerging suicidal ideation: Started Loloft and

    increased over one month to +mg

    Initiated rela'ation with deep #reathing and imagery

    with 6ary and father

    !etween sessions received a call from mother 6ary

    not practicing rela'ation and more irrita#le with mother

    Session: /2D severe9 6ary feels she is failing therapy

    homework and mother does not understand an'iety

    Discussed chronic communication issues #etween

    6ary and mother who does not have an'iety #ut is veryorgani

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    %ary:lan /2D severity now more apparent9 6ary afraid to

    rela' for even a moment9 $raise 6ary for identifying her an'iety symptoms and

    frustrations with mother

    Slow down pace of 1!T rela'ation module and"or

    e'amine thoughts first Take time to focus 6ary5s understanding of her severe

    /2D and impact of #ack pro#lems, /2D, decreased

    social life on her functioning over several years

    4ork on communication #etween mother and 6ary,and pursue further family treatment

    1ontinue medication until ma'imi

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    %ary: ;ighlights

    1onsider severity in starting with 1!T or 1!T

    and meds

    $ace of 1!T depends on what patient can

    tolerate: emphasi

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    Case )xample: Clarence

    /2D, S2D, Social $ho#ia

    2D&D, DSocial skills deficit

    Case )xample: Clarence "history# * year old #oy with 2D&D referred for severe ;sleep

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    * year old #oy with 2D&D, referred for severe sleep

    an'iety= and meets criteria for /2D, S2D, Social $ho#ia,

    71D traits9

    2n'iety #ecame significant after ro##ery of family property Byears ago: credit cards stolen9 Some $TSD features9

    Father travels often with jo#9 Father with possi#le 71D

    traits, low frustration tolerance for Thomas9 Thomas overly

    dependent on mother9

    2n'iety at night sometimes makes it hard to even sleep well

    in mother5s room .no one resting in family0

    2D&D, severe and D impacting academic and social at

    school .irritating to other children0

    2n'iety limits social activities: fearful of #eing away frommother, assertiveness skills and social skills poor .#ullied #y

    students at school0

    )xample: Clarence "0reatment#

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    )xample: Clarence "0reatment#

    2D&D com#ined type interfered with 1!T9 %e8uired

    numerous med trials responded to com#ination ofStrattera, 2dderall .M% and regular0 and /uanfacine

    .appetite suppression, increased irrita#ility, increased

    an'iety on various 2D&D meds0

    )arious SS%I5s tried: tended to get hyperarousal,irrita#le on several with good results on 1ele'a9

    $ositive reinforcement chart set up with clear rewards

    and conse8uences9

    4orked on power struggles and active ignoring9 3sta#lished team with mother, school, and therapist9

    )xample: Clarence "0reatment#

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    )xample: Clarence "0reatment# %ela'ation: deep #reathing, muscle rela'ation, and

    imagery .light #lue, #each scene0 $ositive self-talk: fears other children think he is

    stupid, do not want him as a friend, want him to feel#ad9

    Fears of ro##ers #reaking into house at night and

    killing him and family9 2ny sounds would trigger this9&ow likely 4hat else could sounds #e Safety ofcommunity 2lternative thoughts

    Sytematic desensiti

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    C e ce " e e #

    Social skills training and assertiveness training to

    address response to #ullying along with coordinationwith school to monitor9

    earning meeting and greeting, how to treat play date,

    tolerating small frustrations with peers

    Ignoring ver#al #ullying, responding with humor,monitoring reactions on face and #ody to potential

    #ullies9 /etting help from adults when needed9

    Family treatment to address need for acceptance

    from father9 4ork on gaining competence versusdependence on mother9

    >ew social and interpersonal challenges of

    adolescence

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    Clarence: ;ighlights

    Treat predominant or most impairing

    symptoms first: comor#idity

    isten to family5s major concerns: ;sleepan'iety=

    1onsider social functioning as an important

    outcome

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    Case example: 3immy

    Selective 6utism

    Social 2n'iety Disorder

    )xpanding Safety zone

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    p g y From clinic to school

    K Select transition agent.s0 - parent,therapist, si#s, even classroom teacher

    K Select strategies

    K Select se8uence of e'posures From home to school

    K Select transition agent.s0 - parent, si#s,

    classmates, teacher

    K Select strategies

    K Select se8uence of e'posures

    => Stages in Speech )mergence in

    S h l "l #

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    School "least to most#

    19 1unningham5s workH adapted #y Genny,Fung, 6endlowit Stages in Speech )mergence

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    => Stages in Speech )mergence

    in School "cont7d#*: Speaks to one peer w" normal volume

    : Speaks softly or whispers to several peers

    +: Speaks in normal voice to several peers++: Speaks softly or whispers to teacher

    +B: Speaks in normal voice to teacher

    +J: >7%62 S$331& I> S1&77

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    Case example: 3immy

    @ +"B yo male, living with parents,#ilingual Spanish-3nglish

    >ormal pregnancy, development Shy temperament: S6 since age B9 1omor#idities: Social $ho#ia, Speech

    2rticulation disorder Family history of: /2D, Social $ho#ia,

    Depression, 2lcohol 2#use, Speechtherapy in father

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    3immy "cont7d#

    %egular pre-school

    Stage +-B for speech emergence

    2ccepted #y a few classmates, afraid ofteacher

    School felt he would ;grow out of it=

    Conversational ,isits

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    Peopleto visit .family, neigh#or, friend0 2ies of dayto visit .#efore school, recess,

    lunch, after school, evening0

    Places to visit.private setting to classroom0

    2ypes of activitiesto stimulate speech

    .games from home, computer, art, reading0

    6ake a ta#le of a#ove and rate the amount ofcomforta#le speaking encouraged #y each

    activity

    3immy * )xpanding Safety ?one

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    from ;ome to Clinic 1!T approach, adapted for young child

    $ositive sticker chart

    6edication

    P 1!T emphasis on #ehavioral .due to young age0 with

    some use of superhero themes

    P 2n'iety shrunk as super Qimmy grew strongerP (sed play, drawings, and nature walks as medium of

    engagement

    P Deep #reathing, #each imagery, petting stuffed animal,

    sound of shell to help with rela'ation

    P %ewarded regularly, often for his efforts at home and in

    session9 %ewarded for practicing and success with

    e'posures9

    3immy* )xpanding Safety ?one to

    Cli i C ti d

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    Clinic Continued $t relieved that an'iety had a name and that he could

    con8uer it .worry monster- #ig green #lo#09 2ttacked itin drawings on dry-erase #oard and puppet play

    Individual to parallel play to cooperative play $arents, #rother, cousin in session

    Descri#ed aloud Qimmy5s activities during play Initiated Loloft li8uid at mg and eventually up to

    Jmg with significant improvement in nonver#alcommunication, initiating social interactions,

    whispering, and then speaking 4orked on eye contact, volume of speech, greetingskills, assertiveness skills9 2ngry e'pression hardest9

    $racticed social skills with visits to office ;neigh#ors=in the clinic

    3immy* )xpanding Safety ?one

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    3immy )xpanding Safety ?one

    to School

    %eviewed various school environments for#est ;fit=9 Decided to change schools #ased onstructured social opportunities availa#le

    $sychoeducation with school team and parents

    Set up #rief, fre8uent play dates at home with

    peers from school with parents utili

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    School Continued

    First: parent and Qimmy visit schoolplayground

    Then, parent and Q visited classroom alone Then, parent and Q visited with cousin in

    classroom Then parent, Q, cousin, and teacher $t talking to cousin in classroom 3ventually speaking with teacher and

    classmates 1urrently: Stage +J

    >ew focus: Initiating social interactions incrowded places

    3i ;i hli h

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    3immy: ;ighlights

    $sychoeducation for parents and educators very

    important

    Treating parental an'iety and assisting with

    reactions of relatives, parents5 frustrations (tili

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    ,)S&9,C)S AND,)F),)NC)S

    1linician

    $arent1hild

    +

    eferences for Parents -Teachers H l i Y A i Child (R

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    Helping Your Anxious Child (Rapee,

    Wignall, Spence, Cobham, 2008)

    e!s "o #aren"ing Your Anxious Child

    ($anassis, 2008)

    %reeing Your Child &rom Anxie"!

    (Chans'!, 200) %reeing Your Child &rom C*

    (Chans'!, 200+)

    Helping Your Child i"h Selec"i-e$u"ism ($cHolm e" al, 200.)

    When Children Re&use School/ #aren"

    Wor'boo' (earne! Albano, 2001)++

    ,eferences for Children 4h t T D 4h E 4 T 6 h

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    +++

    4hat To Do 4hen Eou 4orry Too 6uch.&ue#ner, B0

    2 !oy and a !ear: The 1hildren5s %ela'ation!ook .ori ite, +C0

    !link, !link, 1lop, 1lop: 4hy Do 4e DoThings 4e 1anRt Stop 2n 71D Story#ook

    .6orit< Qa#lonsky, B+0

    Talking !ack to 71D .Qohn 6arch, BC0 For children, teens and parents 4hat To Do 4hen Eour !rain /ets Stuck: 2

    Gid5s /uide to 71D .&ue#ner, BA0

    ,esources for Adolescents

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    ++B

    My Anxious Mind- A 2een;s +uide toMana"in" Anxiety and Panic %2op#ins 0Martine:, >88?&

    (idin" the 4ave 4or#$oo# %Pincus,

    Ehrenreich 0 Spie"el, >88@& foradolescents with panic disorder

    Anxiety Disorders %Connolly, Sipson 0

    Petty, >887& for iddle 0 hi"h schoolstudents to help the understand anxietydisorders and reduce sti"a with storiesand drawin"s fro youth with anxiety.

    eferences for Clinicians

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    2reatin" Anxious Children and Adolescents

    %(apee, 4i"nall, =udson0 Schnierin", >888&

    Co"nitive 3ehavioral 2herapy with Children-A +uide for the Counity Practitioner%Manassis, >88?&

    Master of Anxiety and Panic for Adolescents(idin" the 4ave, 2herapist +uide %Pincus,Ehrenreich, Mattis %>88@&

    Practice Paraeter for the Assessent and2reatent of Children and Adolescents withAnxiety Disorders %AACAP >88B&

    ++J

    CBT Anxiety Therapy Man!als

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    Coping Cat.$hillip Gendall0

    and CAT %for adolescents&

    How I Ran OCD Off My Land .Qohn 6arch0

    Meeky Mouse Therapy Manual: CBT

    rogra! for "ele#ti$e Mutis!.D9 Fung, 29

    Genny S9 6endlowit

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    reschool C/0 %anual for 0SD

    2vaila#le from Dr9 6ichael Scheeringa

    mscheertulane9edu

    6anual authors: 69 Scheeringa 6D,

    Q9 1ohen 6D and 9 2maya-Qackson 6D

    ++

    ,)S&9,C)S>ational 1hild Traumatic Stress >etwork

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    >ational 1hild Traumatic Stress >etwork

    www9musc9edu"tfc#tH www9nctsnet9org2merican 2cademy of 1hild 2dolescent$sychiatry .2212$0 www9aacap9org2n'iety Disorders 2ssociation of 2merica

    .2D220 www9adaa9orgS6 /roup- 1hild 2n'iety >etworkwww9selectivemutism9org2ssociation for !ehavioral and 1ognitive

    Therapies www9a#ct9org7#sessive 1ompulsive Foundation

    www9ocfoundation9org!oston (niversity an'iety clinic

    www9childan'iety9net ++C

    %&,) ,)S&9,C)S

    http://www.musc.edu/tfcbthttp://www.nctsnet.org/http://www.aacap.org/http://www.adaa.org/http://www.selectivemutism.org/http://www.abct.org/http://www.ocfoundation.org/http://www.childanxiety.net/http://www.childanxiety.net/http://www.ocfoundation.org/http://www.abct.org/http://www.selectivemutism.org/http://www.adaa.org/http://www.aacap.org/http://www.nctsnet.org/http://www.musc.edu/tfcbt
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    %&,) ,)S&9,C)S

    www9chadd9org for adhd in children and

    adults

    www9#pkids9org for 1hild and adolescent

    #ipolar foundation

    4e#site for $6D1 at (I1 .pediatric mood

    disorders clinic0 and %2I>!74 program

    through www9uic9eduat J+B"C-AABJ ocfoundation

    http://www.uic.edu/http://www.uic.edu/