Anti Aging program with Stem Cells
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One day we will be able to live to be 1000!
TURN BACK THE CLOCK
WITH STEM CELLS
The goal of anti-aging
IS TO GET AND KEEP YOU WELL & HEALTHY RIGHT UP TO THE INSTANT YOU
DEPART THIS LIFE.
THESE ADDED QUALITY YEARS ARE ONES YOU CAN USE TO DO & SEE ALL THE
THINGS YOU VALUE MOST IN LIFE -- AND THEN AND ONLY THEN TO EXIT STAGE
LEFT AT A RIPE OLD AGE ONE METHUSALEH WOULD ENVY!
Sound impossible?
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Life expectancy is increasing in the developed world.
But Cambridge University geneticist Aubrey de Greybelieves it will soon extend dramatically to 1,000.Here, he explains why.
Aging is a physical phenomenon happening to our bodies, so
at some point in the future, as medicine becomes more and
more powerful, we will inevitably be able to address agingjust as effectively as we address many diseases today.
In the classic movie Sleeper (1973) Woody Allen as Miles Monroegoes into a hospital for minorsurgery, dies on the operating table, is cryogenically frozen and then revived in the year 2123. After this
future day Rip Van Winkle comes to himself the doctor in charge explains to him what has happened.
Miles response? He adamantly refuses to believe what he has been told and concludes that the whole
story is something concocted by his friends and the doctor is an actor hired by them as part of the ruse.
The doctor then assures him that everything that is transpiring is real, his friends are all long dead, and
he would be wise to prepare himself to start a new life. Woody refuses to believe what the MD is telling
him and exclaims, "I had a health food store and all my friends ate brown rice. They can't be dead!"
=As funny as Woodys characters denial of reality is, his comment on brown rice is priceless precisely
because it carries to absurdity something very genuine. That is, there is within most of us an abiding
hope that the multi-vitamins we chuck down and health foods we eat will somehow help us cheat death
or at least hold the Grim Reaper at bay for years if not decades. Of course, most of us also realize deep
down that relying on multi-vitamins and organic foods including brown rice for life extension is wella
long shot at best and absurd at worst. After all, people have been doing this sort of thing for more than
4000 years and no evidence has surfaced yet to show that these health faddists live longer than other
Aubrey de Grey: "The first person tolive to 1,000 might be 60 already"
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folks. However for those of us who believe in the power of organic foods and supplements, maybe we
do stay healthier longer than we would otherwise and enjoy a quality of life that is better than we would
have known had we not eaten well and taken our multi-vitamins. The jury is still out on this but many of
us believe this is at least the right direction for a prolonged and healthy lifespan!
Of course, insight into the aging process and how to combat it has grown by leaps-and-bounds in years
since Sleeper debuted. And with this the hope of staving off death and prolonging quality life has
moved beyond the simplistic and sometimes (yes) comical pronouncements of health food faddists,
wishful thinkers, mystics and (ahem) Hollywood playwrights. The most optimistic of all scientists is
Aubrey de Grey who claims that we are close to having the ability to live to be 1000 because
of the SENS (Strategies for Engineered Negligible Senescence) project he is working on to
prevent and cure ageing.
The real problem of the older person is that the methods we have today to help rejuvenate and
regenerate the myriad degenerating and increasingly dysfunctional tissues contained within each of our
aging bodies is that we just dont know how to best invest our time and money to get the most effective
regeneration possible. No one has yet been able to study and compare the various treatments that are
offered by thousands of different types of health practitioners to tell us which of these are truly
effective, safe and actually Reverse the Clock!
After 40 years of practicing alternative, integrative and complementary medicine along with standard
internal medicine, general practice and oncology, physician and stem cell expertDr. David Steenblock
has had most of the different types of health practitioners in his clinic to see what these professionals
could offer his patients. He reports that they all have a place and purpose but in terms of true
regeneration, he states,
..in terms of true regeneration, I
have never seen any treatment more
effective than stem cells and growth
factors to Reverse the Clock!
Dr. David Steenblock
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to
To coin an old phrase, you cant get to where you want without knowing where you are! When it comes
to anti-aging this means you need some idea of what shape you are in and how old your body actually is
(Both being interrelated and interdependent.) The fact is your actual chronological age which may be
considerably higher or lower than the number of birthday candles on your last birthday cake! A sixty
year who is 40 pounds overweight, smokes and abuses alcohol may be in the same physical shape as the
average 70 or 80 year old, while a fit and active 70 year old whose diet & lifestyle is healthy may be 60
or younger. There has been and continues to be an intellectual war between scientists who work in the
laboratory, study and write scientific articles about their findings in cell cultures, genes, proteins,
hormones, etc. and what aging does to these and what they have discovered that can reverse some of
these molecular age related changes and the practicing physician who is really the person in charge of
reversing the age related medical/physical problems that seem to accumulate with aging no matter
what our diet or life style is or has been. Is it aging or pathology is the question that has been debated
and in general the two are so intertwined that it is foolish to think of one without the other. For example
the body needs active healthy stem cells AND growth factors to repair the damage that occurs in the
body and all of its tissues on a daily basis. After age thirty (30) we start to have a decline in the amounts
of growth factors and the viability and functionality of our bone marrow stem cells. IN THEORY IF WE
CAN KEEP GROWTH FACTOR LEVELS AND STEM CELLS FUNCTIONING AT THEIR OPTIMUM LEVEL AS ARE
THE CASE WITH 21-30 YEAR OLDS WE COULD WELL OUTLIVE THE LONGEST LIVED PERSON
DOCUMENTED IN HISTORY. A thousand years of living without getting run over by a truck or visited by
some other natural disaster is expecting too much but living to be a healthy 100 year old is now within
our reach if we take care of ourselves by adopting good preventive lifestyles and then, as we develop
various problems, fix them with the latest tricks that such as stem cells, growth factors and a host of
other modern medical tools.
One quick way you can determine your actual or real age is to use Dr. Ozs Real Age Calculator which
can be accessed by clicking this link:http://www.realage.com/landing/entry4?cbr=GGLE10037X (Note:
This calculator is geared for people over 40 years of age.)
If you havent had a physical exam in more than two years get this done. Then have your doctor give his
or her estimate of your biological age. Then take this number and add it to the one you came up with
http://www.realage.com/landing/entry4?cbr=GGLE10037Xhttp://www.realage.com/landing/entry4?cbr=GGLE10037Xhttp://www.realage.com/landing/entry4?cbr=GGLE10037Xhttp://www.realage.com/landing/entry4?cbr=GGLE10037X -
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on the Real Age Calculator and divide this by two. While this is by no means hard science, it will at
least give you an idea of where you are age-wise. More important than your biological age is the
condition of each of your vital organs. A diseased heart can put an immediate end to a person with a
young biological age! Each of your organs is vital to your health and if you develop a problem
involving one or more of these, the sooner you discover the cause and correct the problem the longerand healthier you will be. Centenarians are people who live to be over 100 years of age and the one
thing that they all have in common is a lack of risk factors. That is to say they generally dont have high
blood pressure, high cholesterol, are not obese, eat healthy, exercise regularly, are not overly stressed
out and generally have not been ill at all during their lifetimes. Thus the lack of repetitive physical
damage is important to living for a long time in good health.
On the flip side a study was conducted many years ago by a Belgium physician who moved to South
Africa to work with the natives after finishing his medical training. What he found were people who
were physically active but had no dental or medical care and so were constantly suffering from one
infection or another from the time of their births. These indigenous people had a lifespan of 28-30 yearsof age the same lifespan of our Stone Age ancestors. After 10 years of studying these people his
conclusion was that they died of the consequences of the damaging effects from these repetitive
infections. Infections raise white blood cell counts especially the neutrophils and these neutrophils kill
the invading micro-organisms by releasing enzymes such as elastase which destroys the bodys
connective tissues. For example, pneumonia if untreated with antibiotics and allowed to run its natural
course will either kill the person or leave a large area of destroyed lung tissue where the infection was.
This destroyed tissue then is cumulative and as more infections occur the lungs functions are
compromised and as a result the patient either slowly dies of lack of oxygen owed to the fact their lungs
can no longer shuttle enough oxygen into the body to sustain it optimally or are killed by their next bout
of pneumonia due to the fact their lungs have been weakened by prior infections. In other words it isthe amount of white blood cells circulating in an individuals blood that is critical to long term health. A
red meat eating person will have on the average 10,000 WBC/cubic mm while a strict vegetarian has a
WBC count of half of that (5,000 WBC/cubic mm)! This is another good reason why everyones diet
should include more organic vegetables, grains, nuts, seeds and some fruits. Even this advice has to be
taken with some caution though since there is a group of viruses that are pandemic among Westerners
that are stimulated to grow and flourish in the body often without people even being aware of them.
These are the Herpes group of viruses and include herpes simplex 1 and 2, Cytomegalovirus, Epstein-
Barr virus, and Herpes zoster. Since these viruses use arginine (which is an essential amino acid and
important in vascular health and growth hormone levels) to grow, when a person harbors any one of
these viruses or has a combination of these viruses they will develop outbreaks of cold sores, or genitalsores or become excessively fatigued and/or depressed. At times these infections involve the brain and
the person can develop migraines, multiple sclerosis, Parkinsons, meningitis and even die from these
infections(Some of which they may not be aware they even have.)
Dr. Steenblockhas seen hundreds of patients who have never had their medical problems determined
with respect to cause until he tested their blood to see if they had a chronic herpes virus. Though not
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usually curable it can be put it into remission and keep it there as long as the patient knows what foods
to avoid such as high arginine-containing nuts and seeds (that not only stimulates herpes viruses to grow
and damage nerves and body but also stimulates the immune system which worsens rheumatoid
arthritis, autoimmune conditions, fibromyalgia, allergies, skin problems, Parkinsons, multiple sclerosis,
Alzheimers, pulmonary fibrosis and any other condition that has inflammation as a component!)
Another good example of these problems is illustrated by Parkinsons disease. Parkinsons patients have
immune and detoxification problems compared to healthy people of the same age. They have
exaggerated inflammatory responses to bacterial and fungal infections which may be due to the
amounts of heavy metals like copper, iron, mercury and lead in their brain, intestinal tract and the rest
of their body. These metals accumulate in these people for a variety of reasons some of which are from
environmental exposures including excessive consumption of heavy-metals sequestering fish and in
some genetic issues and problems that together facilitate increased absorption of these heavy metals as
well as intestinal bacteria and their cell wall components. Endotoxins and Bacteria derived peptide
(fMLP) have been found to be toxic to dopamine neurons and cause selective dopamine neuron loss atvery low levels- the type of levels that can be produced from straining to pass stool, poor dental care
and from consuming too many salted nuts and seeds, refined sugars, acid foods, alcohol and other
intestinal tract damaging substances that allow these bacterial and fungal poisons to migrate through
the intestinal wall into the blood stream. From the blood, these endotoxins and bacteria derived
peptides are picked up from the blood by the astroglia that line the brains blood vessels and whose
function (in part) includes protecting delicate neurons from these toxins. These poisons stimulate the
blood-brain-barrier astroglia to make free radicals that cause damage to the nearby dopamine
producing cells (and this by using up the free radical-scavenging glutathione normally present within
astroglia that is needed to detoxify chemical poisons generated by internal metabolic processes or
which enter the body from outside sources.)
If you have been a couch potato much of your life, smoked, boozed it up or have a chronic disease like
diabetes (Type 2) or have had a stroke your actual or real chronological age is probably more than a few
years more than your clock age. In this instance the immediate goal is to offset this damage and
promote healing and restoration. This will help set the stage to push the biological clock backwards as
you stop and hopefully repair these damaged tissues.
ANTI-AGING EQUIPMENT IS NEEDED TO REVERSE THE CLOCK
One medical issue that shows up very often in 30+ year olds is arterial calcification and atherosclerosis
(blood vessel blockage.) Of course the percentages of people having these problems worsen the older
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you are but occasionally you will see a young person even under 30 with the condition and sudden
death may be the first sign of the problem! Diagnosing these before they become a personal tragedy is
fairly straightforward (although often not tended to) though halting and reversing them is not. Dr.
Steenblock recommends that everyone with a family history of heart disease have a quantitative
Calcium Artery Score (CT scan) done beginning at the age of 30 and if clear then every 5 yearsthereafter. This particular test is the best and least expensive early warning test for coronary artery
disease there is in Steenblocks opinion and not surprisingly he has been ordering them for his patients
since 1990! When coronary artery calcification is found there is a very high probability the patient is
heading for a heart attack sooner or later. The goal is to have a zero on this test meaning little or no
calcium in coronary arteries as the more calcium seen on the scan of heart arteries the more
atherosclerosis a parson has building up in his arteries and the more likely she will soon be having a
heart attack, stroke or other vascular problems! When discovered by most conventional doctors they
typically deal with these conditions by simply prescribing drugs like statins that tend to wind up doing
more harm than good over time; Prescription pad medicine, in short. Physicians should take a
different and more heads-on approach by fully identifying and directly dealing with the underlyingdisease processes and mechanisms. Arterial calcification can be due to over 240 different agents or
mechanisms! Sifting through all of these causes can take a fair amount of effort by a physician and may
require some work on the patients part to eliminate the underlying causes. For instance, calcium
deposits on artery walls leads to them becoming stiff and hard which causes high blood pressure.
Because the arteries no longer can expand optimally due to these calcium deposits the amount of red
blood cells reaching vital organs from second-to-second is compromised which means a decrease in
oxygenation of vital tissues. If this occurs to the brains blood vessels an individual starts to become
forgetful, can no longer can do math in their head like they once could, start to forget home telephone
numbers or addresses, etc. This sets them up for permanent dementia since arterial calcification and/or
hypoxia is the direct cause of strokes, heart attacks, kidney failure, macular degeneration, arthritis,diabetes, etc.
Lack of oxygen likely causes or contributes to
most all of the diseases associated with the aging
process
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Photo on left: Calcified artery behind knee joint
Removal of calcium from arteries should be facilitated by taking more oral magnesium, intravenous
EDTA chelation therapy, taking vitamin K-2 (Menaquinone-7) by mouth, use of parathyroid hormone
injections (Forteo), lowering cholesterol, avoiding dairy products, eating lots more green and yellow
vegetables. The fructose in fruits has been shown to accelerate the process of atherosclerosis so people
need to limit fruit juices if possible and drink spring water, green tea or green vegetable juices.
One thing people serious about antiaging should do is work with a physician to determine if sufficient
oxygen is reaching their organs and tissues. While it is very difficult to accurately measure the levels of
oxygen reaching each organ there is a simple noninvasive test called a nocturnal oximetry test that
easily and readily reveals whether oxygen levels in the blood are falling off too much during sleep. This is
actually a good way to access oxygen status as drastic drops during sleep due to sleep apnea or other
medical conditions can damage the brain and other organs. If dramatic drops are noted the cause or
causes is identified and then remedied or managed.
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Nocturnal Oximetry Device
The machine that is used to do nocturnal oximetry testing is like a small tape recorder which is obtainedfrom a physician and used at home. To use this device one puts a small non-painful clamp on a finger,
turns the machine on and then goes to sleep. In the morning the clamp is removed and the machine is
shut off and returned to the dispensing doctor. He or she will then prints out the sleep oxygen record,
notes any problems and deals with this.
If this test indicates poor oxygenation is occurring,Dr. Steenblocklooks for causes or contributors such
as obesity, alcohol intake, sleep apnea, strokes, transient ischemic attacks, etc. and then introduces
therapeutic measures aimed at boosting oxygen flow. Sometimes this is as
simple as losing excess weight while in others he prescribes a course of
Hyperbaric Oxygen Therapy(HBOT.)In HBOT a patient sits comfortably in apressurized mini-submarine like chamber and breathes pure oxygen.
The pressure in the chamber is typically set to approximate what is
experienced at an ocean depth of about 33 feet. This drives oxygen into the body and saturates tissues
and organs which not only counters hypoxia but also boosts the levels of antioxidant compounds such as
superoxide dismutase (SOD), glutathione, etc. and appears to increase the rate of nerve regrowth
(Nerve regrowth is a very desirable goal in patients with brain damage from a stroke or such or whose
peripheral nerves have been damaged by diabetes.)
Depending on the nature and extent of the arterial calcification and/or atherosclerosis that is present,Dr. Steenblockprescribes other treatments that will help the body reverse these. In some instances this
involveschelation therapyto remove toxic, blood vessel wall damaging heavy metals from a patients
body and use ofExternal Counterpulsation(EECP), an FDA approved machine that increases blood flow
to organs and tissues, and actually facilitates the growth of new blood vessels. The effects of EECP are
often so dramatic as to produce what many doctors characterize as a natural bypass.
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The External counter Pulsation machine is specifically used to increase blood flow tothe heart to treat angina (FDA approved for this) and congestive heart failure; to the lungs in those with
emphysema; to the liver in liver failure cases; to the kidneys in instances of chronic kidney failure; to the
eyes for macular degeneration and glaucoma; to the brain for strokes, Parkinsons, sleep apnea,
Alzheimers, etc. and to legs and feet for the treatment of atherosclerosis, calcification and gangrene of
the legs and feet.
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Exercise, too, is helpful for many people with cardiovascular disease, but unfortunately some are not fit
enough to handle intense physical exertion such as short-duration intense exercise. This type of
exercise is the very best there is to release the stem cells from your bone marrow. The more stem cells
circulating in your blood the healthier you are! One alternative to short-duration intense exercise is
Periodic Acceleration Therapy(PAT). In PAT a person lies prone on a sophisticated mechanized
platform and
gets a moderate cardiovascular work-out via a gentle back-and-forth motion. What this does is create a
very mild stress on blood vessels that gets them busy producing Nitric Oxide (NO) and VEGF which
confers all kinds of health benefits including facilitating better blood flow to organs and tissues body
wide. NO also plays a role in the mobilization ofa persons own stem cells from their bone marrow and
VEGF (vascular endothelial growth factor) is felt to help the stem cells enter into the tissues while having
the PAT where they can start to grow and make new tissues . Dr. Steenblock recommends this
treatment be given daily and especially after a patient has had stem cells or has been given bone
marrow stem cell releasing agents like Neupogen. Generally, Dr. Steenblock gives patientsNeupogen on a daily basis (typically right after they arrive at his clinic) so that in 2-3 hours time their
bone marrow has released large numbers of stem cells which then have a better chance to get to
where desired and then to grow in those areas of the body that has been damaged or diseased.
Of course, obvious arterial disease is not always present in those seeking to combat aging but excess
calcium in ones arteries is always present in those of us who attain the age of 50. In general a 60 year
old has 10 times more calcium in the walls of their arteries than a 10 year old has. Some studies are
showing that 80 year olds have up to a 100 times more calcium in their arteries than 10 year olds! Some
folks will have healthy serum cholesterol & glucose levels and arteries as clean as a whistle but have
other chronic health conditions such as arthritis. As many chronic medical conditions involve oxidativestress or a compromised ability to deal with cell-damaging free radicals, Dr. Steenblock does tests to
assess this. When an individuals body is not handling free radicals well or is overproducing them a
therapeutic agent or treatment is prescribed to correct or offset this. In some instances this may be as
simple as introducing an antioxidant-rich diet along with specific antioxidant supplements.
http://www.zimbio.com/Interval+Training/articles/KyKFal20BBE/Short+bursts+intense+exercise+better+longhttp://www.zimbio.com/Interval+Training/articles/KyKFal20BBE/Short+bursts+intense+exercise+better+longhttp://www.zimbio.com/Interval+Training/articles/KyKFal20BBE/Short+bursts+intense+exercise+better+longhttp://www.zimbio.com/Interval+Training/articles/KyKFal20BBE/Short+bursts+intense+exercise+better+longhttp://stemcell.md/newsletters/sept2010.pdfhttp://stemcell.md/newsletters/sept2010.pdfhttp://davidsteenblock.com/about/http://davidsteenblock.com/about/http://davidsteenblock.com/about/http://davidsteenblock.com/about/http://davidsteenblock.com/about/http://davidsteenblock.com/about/http://davidsteenblock.com/about/http://davidsteenblock.com/about/http://davidsteenblock.com/about/http://davidsteenblock.com/about/http://stemcell.md/newsletters/sept2010.pdfhttp://www.zimbio.com/Interval+Training/articles/KyKFal20BBE/Short+bursts+intense+exercise+better+longhttp://www.zimbio.com/Interval+Training/articles/KyKFal20BBE/Short+bursts+intense+exercise+better+long -
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Another thing that Dr. Steenblock looks at is hormone levels. DHEA (5-Dehydroepiandrosterone), for
instance, declines with age and is supplemented when its use is not contraindicated (which is the case in
some people who have specific diseases or metabolic conditions.)
Stem cells are considered an important player in the anti-aging equation by Dr. Steenblock and many
other doctors because both the creation of new tissue and repair of damaged and diseased tissue are
dependent on stem cells that reside in the bodies various organs and tissues. Mesenchymal stem cells,
in particular, are vital to the bodies repair and maintenance as these have the ability to become a wide
range of cells such osteoblasts (bone cells), chondrocytes (cartilage cells), adipocytes(fat cells) and
neurons and their supporting glial cells. When this cache of stem cells is devitalized or hampered in
carrying out their functions not only is healing compromised but the body itself may age prematurely.
One of the major sources of stem cells in our bodies is bone marrow. Each of us, in fact, has in the
hollows of our bones both red bone marrow tissue and yellow fat. When we are very young our bones
are full of active healthy bone marrow that is growing and releasing healthy stem cells 24/7 year round.
This is one reason why children can heal so much better than older people. But, as people get older their
bodies make less new tissue especially that in the bones, and as a result there is a shift in the amount of
red bone marrow to yellow bone marrow (which indicates there is fat present and no longer the same
amount of stem cell producing red bone marrow). This loss of red bone marrow means there are fewer
stem cells being manufactured so less are released into the circulation and there are not enough to go
around to repair damaged tissues and to prevent the loss of tissue due to aging. Thankfully, Dr.
Steenblock has figured out how to coax bone marrow to replace these senescent stem cells withhealthy, vital ones. One way in which he does this is to treat patients withIntermittent Hypoxia Therapy
which actually induces a temporary state of hypoxia or oxygen depletion in patients. This short-term,
calculated, induced hypoxia stimulates bones to produce more stem cell rich bone marrow. This
treatment is generally done in tandem with P.A.T. (Periodic Acceleration Therapy) and Functional
Electrical Stimulation (of muscles and bones.) All three together are believed to release stem cells from
bone marrow if done concurrently!
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For a video on the use of intermittent hypoxia for rejuvenation go to this website:
http://www.youtube.com/watch?v=GMpyA5-Q2hs
For the older person over fifty (50) Dr. Steenblock usually recommends hormones called colony
stimulating factorsto prod the body to mobilize senescent (non functioning) stem cells into the patients
blood stream. After a course of these injections it is believed that basically only healthy stem cells
remain behind in the marrow and these then begin reproducing very rapidly in order to replace the cells
that have been mobilized. Dr. Steenblock feels that in two weeks time a
patients bone marrow can have upwards of 10 times
more healthy stem cells than were present prior to the
injections.
Once a patients bone marrow is brimming with robust, healthier stem cells,Dr. Steenblockharvests this
and gives it back to patients by intravenous (IV) drip or in some instances by other routes. In terms of
antiaging this basically floods the body with stem cells which are believed to fan out, engraft in organs
and tissues and effect healing and restoration. Not surprisingly, many people who
have had this treatment have reported seeing anti-
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8/4/2019 Anti Aging program with Stem Cells
14/14
One day we will be able to live to be 1000!
aging effects like better skin color, a healthier
glow and fewer wrinkles.
More recentlyDr. Steenblockadded the use offat derived stem cells(by themselves or in combinationwith bone marrow) to combat various diseases as well as aging.
If you are serious about tackling aging, this is not something you can do on your own. Indeed, the only
way to do this right is to involve a doctor-partner who is an expert in both chronic disease & antiaging
medicine; someone who knows how to zero in on what a person needs and then make sure they get it.
This is Americas antiaging and more doctorDr. David Steenblock..
For more information or an appointment call toll free 1-800-300-1063
2011 by David A. Steenblock, D.O., Inc. All rights reserved. This document and the information in it is
not to be used as a substitute for medical advice, diagnosis or treatment of any health condition or
problem. Any questions regarding your own health should be addressed to your physician or other
licensed healthcare provider.
IMPORTANT DISCLAIMER: The use of stem cells or stem cell rich tissues as well
as the mobilization of stem cells by any means, e.g., pharmaceutical, mechanical
or herbal-nutrient is not FDA approved to combat aging or to prevent, treat, cure
or mitigate any disease or medical condition mentioned, cited or described
herein.
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