Analytical Assessment Technology Advancements &...
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Analytical Assessment Technology Advancements & Common Analytical Pitfalls Mike Ericson Laboratory Director Con-Test Analytical Laboratory
Transcript of Analytical Assessment Technology Advancements &...
Analytical Assessment Technology Advancements & Common Analytical Pitfalls
Mike Ericson
Laboratory Director Con-Test Analytical Laboratory
Analytical Assessment Technology Advancements and Common Analytical Pitfalls
Michael Erickson
PCB Structure
Aroclor 1242
PCB 18
• Aroclors are comprised of varying ratios of the 209 PCB congeners
• Aroclor mixtures are characterized by the amount of chlorine they contain (i.e. 1242 contains 42% chlorine)
IUPAC # Compounds Isomer Class Homologues 1 2-Chlorobiphenyl 1 Cl 2 3-Chlorobiphenyl 1 Cl Monochlorobiphenyl 3 4-Chlorobiphenyl 1 Cl 4 2,2'-Dichlorobiphenyl 2 Cl 5 2,3-Dichlorobiphenyl 2 Cl 6 2,3'-Dichlorobiphenyl 2 Cl 7 2,4-Dichlorobiphenyl 2 Cl 8 2,4'-Dichlorobiphenyl 2 Cl 9 2,5-Dichlorobiphenyl 2 Cl
10 2,6-Dichlorobiphenyl 2 Cl Dichlorobiphenyl 11 3,3'-Dichlorobiphenyl 2 Cl 12 3,4-Dichlorobiphenyl 2 Cl 13 3,4'-Dichlorobiphenyl 2 Cl 14 3,5-Dichlorobiphenyl 2 Cl 15 4,4'-Dichlorobiphenyl 2 Cl 16 2,2',3-Trichlorobiphenyl 3 Cl Trichlorobiphenyl . . . . . . . . . . . .
206 2,2',3,3',4,4',5,5',6-Nonachlorobiphenyl 9 Cl 207 2,2',3,3',4,4',5,6,6'-Nonachlorobiphenyl 9 Cl Nonachlorobiphenyl 208 2,2',3,3',4,5,5',6,6'-Nonachlorobiphenyl 9 Cl 209 2,2',3,3',4,4',5,5',6,6'-Decachlorobiphenyl 10 Cl Decachlorobiphenyl
PCB Homologues
Dioxin-like Compounds
Similar geometry (planar) and chlorine substitution pattern
Of the 209 congeners 12 are dioxin-like
Three most toxic congeners include PCB 77, 126 & 169 (non-ortho substitution)
Tetrachlorodioxin PCB 77 PCB 54
PCB Extraction Methods
Solids
SW-846 3540C Soxhlet Extraction (TSCA, Region 1)
SW-846 3550C Ultrasonic Extraction
SW-846 3545A Pressurized Fluid Extraction (PFE)
SW-846 3546 Microwave Extraction
Liquids
SW-846 3510C Liquid-Liquid Extraction
SW-846 3535 Solid Phase Extraction
SW-846 3540C Soxhlet Extraction
Analytical Methods
SW-846 8000C
SW-846 8082
Water, Soil, Sediment
Wipes, Paint, Caulking
TO-10A, TO-4
Air – PUF
EPA 680
Homologues
SW-846 8270 Modified
Congeners
Extract Clean-up Methods
SW-846 3665A Sulfuric Acid Clean-up Elevated baselines
Complex chromatograms
SW-846 3660B Sulfur Clean-up Elemental Sulfur in many sediments
Solubility is similar to PCBs
SW-846 3620C Florisil Cartridge Clean-up Polar hydrocarbons
Other polar material
Enhanced column Clean-up Primarily for troublesome caulking
Aroclor 1242 “under” sulfur peak
Aroclor 1242 with Sulfur Interference Removed
Enhanced Clean-up with Interference Removed
PCB’s in Air Sampling
Polychlorinated biphenyls are sampled on a PUF (polyurethane foam) cartridge. High volume samples are taken on large high volume PUF’s by EPA Method TO-4A. Low volume samples can be taken by EPA Method TO-10A.
HIGH VOLUME
LOW VOLUME
PCB’s in Caulking, Air, Wipes…
Typical Reporting Limits
PCB Aroclors in Air*
TO-4A (High Volume) 0.062-0.62 ng/m3
TO-10A (Low Volume) 0.0028-0.83 ug/m3
Optional
NIOSH 5503* 0.069-2.0 ug/m3
* RL calculated from sample volume
PCB 8082 in caulking/paint <1 mg/Kg 0.5/0.2g
PCB 8082 in concrete/brick 0.5 mg/Kg 2g
PCB 8082 in soil 0.1 mg/Kg 10g
PCB 8082 wipes 0.2ug/wipe 1 wipe
PCB 680 Homologues in wipes/air 0.001-0.005µg/homolog
25ng total PCB’s
