An Effective Approach to a Proven Therapy

Why the BAERVELDT® Glaucoma Implant?

• Unique design combines a large surface area implanted in a single quadrant. More surface area provides:

– More effective long-term IOP control1,2

– Increased drainage capacity2

– Potentially fewer postoperative anti-glaucoma medications1,2

Single-quadrant BAERVELDT® Glaucoma Implant May Provide:

• Easier implantation1

• Less trauma to periocular tissue than multiple quadrants2

• Minimal inflammation2

• Improved control of IOP as a result of minimizing inflammation2

Single Implant Surface Area (mm2)

1

3

1

4

The Advantages of the BAERVELDT® Glaucoma Implant

• Single-quadrant insertion1

• Technically easier surgery, requiring only one conjunctival incision compared to 2-quadrant implants1,2

– Reduced surgical time2

– Less trauma to periocular tissue2

The Advantages of the BAERVELDT® Glaucoma Implant

• Patented bleb control mechanism

– Fenestrations allow fibrotic tissue growth, ‘riveting’ bleb to sclera1,5,6

– Designed to control bleb height and volume1,6

– Secures the plate in place6

– Minimizes potential for ocular motility disturbances6

The Glaucoma Implant – Designed for Ideal Pars Plana Implantation

• Exclusive Hofmann Elbow directs the drainage tube for proper placement in the posterior chamber and eliminates the need for trimming or modification.

BAERVELDT® Pars Plana Glaucoma Implant – Designed for Clinical Success

• Excellent IOP control1

• Visual acuity remained the same or improved in 83% of patients (10 out of 12)7

• No reported cases of vitreous incarceration

Reference 8

An Implant Designed from the Surgeon’s Perspective

• Unique design with Hofmann Elbow facilitates proper placement in the posterior chamber

• Eliminates the need to trim or modify the drainage tube for insertion through the pars plana

• Eliminates concerns over potential straightening of the tube

The BAERVELDT® Glaucoma Implants – Effective Implant Designs

• Large surface area for effective IOP control1

• Low implant profile helps reduce complications1

• Single-quadrant insertion for installation with less trauma than double plate

• Fenestrations minimize bleb height and volume to reduce ocular motility disturbances1,5,6

BAERVELDT® Glaucoma Implant Surgical Technique

BAERVELDT® Glaucoma Implant Surgical Technique

BAERVELDT® Glaucoma Implant Surgical Technique

BAERVELDT® Glaucoma Implant Surgical Technique

BAERVELDT® Glaucoma Implant Surgical Technique

BAERVELDT® Glaucoma Implant Surgical Technique

References

1. Lloyd MA, Baerveldt G, Fellenbaum PS, et al. Intermediate-term results of a randomized clinical trial of the 350 - versus the 500 mm2 Baerveldt Implant. Ophthalmology. 1994;101:1456-64.

2. Fellenbaum PS, Sidoti P, Heuer DK, et al. Experience with the Baerveldt implant in young patients with complicated glaucomas. J Glaucoma. 1995;4:91-7.

3. Heuer DK, Lloyd MA, Abrams, DA, et al. Which is better? One or two? A randomized clinical trial of single-plate versus double-plate Molteno implantation for glaucomas in aphakia and pseudophakia. Ophthalmology. 1992;99:1512-19.

4. www.ahmedvalve.com/products/silicone/fp7.html. Accessed March 6, 2006.5. Data on file, Advanced Medical Optics, Inc.6. Hodkin MJ, Goldblatt WS, Burgoyne CF, et al. Early clinical experience with the Baerveldt

implant in complicated glaucomas. Am J Ophthalmol. 1995;120:32. 7. BAERVELDT glaucoma implant package insert, Advanced Medical Optics. 8. Luttrull JK, Avery RL. Pars plana implant and vitrectomy for treatment of neovascular

glaucoma. Retina. 1995;15:379-87.

BAERVELDT is a registered trademark of Advanced Medical Optics, Inc.