American Academy of ozonoterapy
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Transcript of American Academy of ozonoterapy
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American Academy of ozonoterapy
Annual Meeting 2014
Dallas March 26-29 2014
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OZONE THERAPY AND
MULTIPLE SCLEROSIS:
WHY?
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NIRS Test: After 1 hour from starting reinfusion O2Hb increase in the frontal lobes, despite the constancy of carotid flow: a clear sign of increased
microvascular perfusion and increased reactivity of hemoglobin
Levy Reinfusion
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NIRS signal during therapy O2Hb and HHb
Thear is an increase of cerebral oxygenation for a long period , maximum from 20 minutes to 1,5 h after re-infusione .
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TCD signals during therapy
That is small variation of hematic flow.
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Specific study of MS
Complete analysis in time-frequency of NIRS segnals among 4 MS R-R and 5 heathy patients. Variation quantifier in time and frequency of cytocrome-c-oxidase concentration.Analysis by Principal Component Analysis program
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Changes of CYT-c-oxidase
• Less concentration of CYT-c among MS patients, caused by damages of
mythocondrions• MS patients have cronich oxidative stress• Ozonotherapy has anti-oxidant effect antixidant enzymes increase• Ozonoterapy may reduce oxidaditve stress in MS
Bibliography
• Low CYT-c in MS• CYT-c increases after 20’ to 40’ of reifusion• Higher level of CYT-c is a diagnostic value between MS patiens and other
patiens
OUR experiment results
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MS: Contemporary THERAPY
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EDSS variactions
*
* P < 0,05
4,3
3,8
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FREQUENCY OF RECIDIVATION/YEAR
0,00%
10,00%
20,00%
30,00%
40,00%
50,00%
60,00%
70,00%
Pre-Ozonetherapy Post-Ozonetherapy
P < 0,05
*
*
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SYMPTOMATOLOGY
P < 0,005*
**
**
**
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FOLLOW-UP
1)No patient got worse
2)All spinals reflex bladders patients got better or recovered