Algorithms Organization Ross Whitaker – Utah Polina Golland – MIT (Kayhan B.) Guido Gerig –...
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Transcript of Algorithms Organization Ross Whitaker – Utah Polina Golland – MIT (Kayhan B.) Guido Gerig –...
![Page 1: Algorithms Organization Ross Whitaker – Utah Polina Golland – MIT (Kayhan B.) Guido Gerig – Utah Martin Styner – UNC Allen Tannenbaum – Georgia Tech.](https://reader036.fdocuments.in/reader036/viewer/2022062409/56649ef45503460f94c07f9c/html5/thumbnails/1.jpg)
Algorithms Organization
• Ross Whitaker – Utah
• Polina Golland – MIT (Kayhan B.)
• Guido Gerig – Utah
• Martin Styner – UNC
• Allen Tannenbaum – Georgia Tech
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Presentations
• Highlights from the 10-year project
• Recent advances
• Clinical/biomedical impact
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Diffusion Tensor Imaging
• Structure, function, connectivity, and schizophreniao Shenton/Harvardo Potkin/Irvine
• Technical challengesoData preprocessingoRobust tools for analysis
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DTI Technical Development
• Denoisingo Basu, et al., MICCAI, 2006
• Susceptibility artifactso Tao, et al., IPMI 2009
• Segmentationo Fletcher et al., IPMI, 2007
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DTI Segmentation
• Volumetric tractography
• Volumetric paths between ROIsoA collection of shortest pathsoUser interaction, visualization, GPU
implementations
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NA-MIC DTI Analysis• Ancillary grant:
Lainhart/Fletcher – DTI analysis in autismo Scientific results
– Arcuate fasciculus in autism, Fletcher et al, Neuroimage, 2010.
– Longitudinal Heschl's gyrus in autism, Prigge et al., 2013.
o Software pipeline
• Broader impact– Cardenas et al., J Neuroimaging,
2013. (UCSF)
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Statistical Shape Modeling
• DBPso Shenton/Schizophreniao Piven/AutismoMacLeod/Marrouche
• Robust, general methods for shape analysis
• Softwareo ShapeWorks
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Technology for Shape Analysis
• Correspondence/parameterization
• Hypothesis testing
• Regression
• Longitudinal analysis
• Scientific resultso Harris et al., J. of Ortho. Res., 2013o Jones et al., J. of Ortho. Res., 2013
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NA-MIC Ancillary Grant
• Anderson: shape analysis in hip pathoanatomy (ongoing)o Shape analysis in hip biomechanicsoDiagnosis and treatment planningoDatabase of parameterized hip models
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Segmentation
• DBPso Sharp/Chen, Head and Neck CanceroMacLeod/Marrouche, Afib
• Robust tools for “difficult” segmentation problemso Low SNRoHigh shape variability
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Bayesian Formulation of LA Segmentation (DCE-MRI)
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LA Segmentation Results
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Slicer Module