AIIMS May 2010 Solution

8/8/2019 AIIMS May 2010 Solution

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85. Streptococcus all are true excepta) Streptodornase cleaves dnab) Streptolysin O is active inreduced statec) Streptokinase is produced fromserotype strep. A,C,Kd) Pyrotoxin A is plasmidmediated

86. Not used in leptospirosisa) Microscopic agglutination testb) Dark field illuminationc) Macroscopic agglutination testd) Weil felix reaction

87. Superantigens true isa) Directtly attached to variableregion of MHCb) Needs to proccessed andpresented to cleft of MHCc) they bind to cleft of MHCd) Presented by APC to T cell

88. CD4+ is not important for which of thefollowinga) Antibody productionb) Cytotoxicity of T cellsc) Memory B cellsd) opsonisation

89. Antigen antibody precipitation ismaximally seen in which of thefollowing?a) Excess of antibodyb) Excess of antigenc) Equivalence of antibody andantigend) Antigen-Hapten Interaction


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PATHO90. Coagulative necrosis seen ina) TBb) Sarcoidosisc) Cryptococcal infectiond) Gangrene

91. Characteristic feature of acuteinflammationa) Vasoconstrictionb) Vascular stasisc) Vasodilatation and increased

vascular permeabilityd) Margination of leucocytes

92. Berry aneurysm Defect lies ina) Degeneration of internal elasticlaminab) Degeneration of media /muscle cell layer c) Deposition of mucoid materialin mediad) Low grade inflammation of vessel wall

93. Which of the following is associated withaginga) Reduced cross linkages incollagenb) Increased free radical injuryc) Somatic mutations in DNA

d) Increased superoxidedismutase levels

94. Caspases are associated witha) Organogenesisb) Hydropic degenerationc) Collagen hyalinization


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d) Not recalled

95. Smoking is a causative factor for all thecarcinomas excepta) Esophageal carcinomab) Laryngeal carcinomac) Nasopharyngeal carcinomad) Urinary bladder carcinoma

96. Barretts esophagus showsa) Intestinal dysplasiab) Intestinal metaplasiac) Squamous cell metaplasiad) Columnar cell metaplasia

97. Hypersensitivity vasculitis affectsa) Post-capillary venulesb) Arteriolesc) Veinsd) Medium-sized arteries

98. Psammoma bodies seen in A/Ea) Follicular CA of thyroidb) Papillary CA of thyroidc) Serous cystadenocarcinoma of ovaryd) Meningioma

99. Central organ in apoptosisa) Mitochondriab) Nucleusc) ERd) Golgi body

100. CD marker specific for myeloid seriesa) CD34b) CD45c) CD99d) CD117


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101. Two siblings with osteogenesisimperfecta.. but their parents arenormal. Mechanism of inheritance isa) Anticipationb) Genomic imprintingc) Germ line mosaicismd) New mutation

Normal parents + one child affected +others normal New sporadic mutation.

Normal parents + two siblings affected Germ line mosaicism

(How do people inherit osteogenesis imperfecta?

Most cases of osteogenesis imperfecta have an autosomal dominant pattern of inheritance, which means one copy of the altered gene in each cell is sufficientto cause the condition. Many people with type I or type IV osteogenesisimperfecta inherit a mutation from a parent who has the disorder. Most infantswith more severe forms of osteogenesis imperfecta (such as type II and typeIII) have no history of the condition in their family. In these infants, thecondition is caused by new (sporadic) mutations in the COL1A1 or COL1A2gene.

Less commonly, osteogenesis imperfecta has an autosomal recessive pattern of inheritance. Autosomal recessive inheritance means two copies of the gene ineach cell are altered. The parents of a child with an autosomal recessive

disorder typically are not affected, but each carry one copy of the altered gene.Some cases of osteogenesis imperfecta type III are autosomal recessive; thesecases usually result from mutations in genes other than COL1A1 and COL1A2.When osteogenesis imperfecta is caused by mutations in the CRTAP or LEPRE1 gene, the condition also has an autosomal recessive pattern of inheritance.)

102. Not true about xanthogranulomatousinflammationa) Associated with TB

b) Yellow granulomac) Giant cells seend) Foam cells seen

103. All of the following genes are implicatedin Carcinogenesis of colon excepta) APC


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b) k-rasc) Beta catenind) Mismatch repair

104. Wilms tumor associated with A/Ea) Hemihypertrophyb) Aniridiac) Hypertensiond) Bilateral polycystic kidney

105. Which of the following is NOT true aboutFAP?a) AR inheritanceb) Screening done with

colonoscopyc) Sigmoidoscopy usedd) Not recalled

MEDICINE106. Hyperextensibility with normal elasticrecoil is a feature of a) Ehlers Danlos syndromeb) Pseudoxanthoma elasticumc) Cutis laxad) Scleroderma

107. Which of the following aboutatherosclerosis is true?a) Intake of PUFA associated withdecreased riskb) Thoracic aorta involvement is

more severe than abdominalaorta involvementc) Extent of lesion in veins issame as that in arteriesd) Hypercholesterolemia does notalways increase the risk of atherosclerosis per se


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108. Not a cardiovascular complication of HIV/AIDSa) Cardiac tamponadeb) Recurrent arterial embolismc) CHFd) Aortic aneurysm

109. A girl presented with severehyperkalemia and peaked T waves onECG. Fastest way of shifting potassiumintracellularly isa) Calcium gluconate IVb) Oral resins

c) Insulin + glucosed) Sodium bicarbonate

110. Features of hypocalcemia are A/Ea) Numbness & tinglingb) Circumoral paresthesiac) Depressed tendon reflexesd) Skin irritability & sensitivity

111. A young man back from leisure trip hasswollen knee joints & foriegn bodysensation in eyes. Llikely cause isa) Reiters syndromeb) Sarcoidosisc) Behcets diseased) SLE

112. Cause of vasodilatation in spider nevia) Estrogenb) Testosteronec) Hepatotoxinsd) FSH

113. Monoclonic and polyclonic cryoglobinsare found in association witha) HBV


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b) HCVc) EBVd) Parvovirus

114. Rapid infusion of insulin causesa) Hyperkalemiab) Hypokalemiac) Hypernatremiad) Hyponatremia

115. Digitalis toxicity enhanced by A/Ea) Renal failureb) Hyperkalemiac) Hypercalcemia

d) Hypomagnesemia

116. True about hemochromatosisa) Is genetically heterogenousb) Cannot be treated byphlebotomyc) Completely penetrantd) More common in female thanmale

117. Strawberry gingivitis seen ina) Myelocytic infiltrationb) Phenytoin toxicityc) Wegener granulomatosisd) Klippel Trenaunay syndrome

118. A patient presents with history of episodic painful edema of face andlarynx. Which of the following is likely tobe deficienta) C3b) C5c) C1 esterase inhibitor d) Not recalled

119. Test for assessment of absorptive


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function of colona) D-xylose testb) NBT-PABA testc) Fecal fat estimationd) Schilling test

120. All are true about temporal arteritisexcepta) Can lead to sudden bilateralblindnessb) More common in femalesc) Worsens on exposure to heatd) Mostly affects elderly

121. A pt presents with acute rheumaticcarditis with fever. True statement isa) Increased troponin Tb) Reduced myocardialcontractilityc) Signs of inflammation andnecrosisd) Valve replacement willameliorate CCF

PEDIATRICS122. All are signs of impending Eisenmenger excepta) Increased flow murmur acrosstricuspid & pulmonary valveb) Single S2c) Loud P2

d) Graham Steele murmur

123. Eisenmenger syndrome True are A/Ea) Pulmonary veins are notdistendedb) RV & LV walls come back tonormal size


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c) Dilatation of central pulmonaryarteryd) Peripheral pruning of pulmonary arteries

124. Chang staging is used for a) Retinoblastomab) Medulloblastomac) Ewings sarcomad) Rhabdomyosarcoma

125. Which CNS tumor metastasizes outsidethe brain in children?a) Glioblastoma multiforme

b) Medulloblastomac) Ependymomad) Choroid plexus tumor

(both medulloblastoma and glioblastoma multiforme metastasisoutside brain BUT in glioblastoma it is seen rarely.)

126. Which of the following is a component of Pentalogy of Fallota) TOF + ASDb) TOF + PDAc) TOF + Coarctation of aortad) TOF + LVH

127. A newborn has been brought withseizures refractory to treatment and acontinuous bruit through the anterior fontanelle. CT shows midline lesion withhypoechogenesity and dilated lateralventricles. Diagnosis isa) Vein of Galen malformationb) Arachnoid cystc) Teratomad) Encephalocele

128. 6 weeks old female baby found


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unconscious suddenly in the crib. Shewas previously healthy. Normal bloodpressure, hyperpigmentation of genitals,blood glucose 30 mg/dl. Diagnosis isa) CAH due to 21-alphahydroxylase deficiencyb) Familial glucocorticoiddeficiencyc) Cushings syndromed) Insulinoma

129. Best indicator of growth monitoring inchildrena) Weight

b) Mid-arm circumferencec) Rate of increase of height &weightd) Head circumference

130. A child presents with failure to thrivewith frequent vomiting,diarrhoea,hepatosplenomegaly &abdominal distension. CT showsadrenal calcification. Which of thefollowing is the diagnosis?a) Adrenal hemorrhageb) Wolmans diseasec) Pheochromocytomad) Addisons disease

131. Most sensitive indicator of intravascular volume depletion in infanta) Stroke volumeb) Heart ratec) Cardiac outputd) Blood pressure

132. An alert 6 month old child is broughtwith vomiting & diarrhea. RR-45/min,HR-180/min, SBP-85 mm of Hg.


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Extremities are cold & mottled. Capillaryrefilling time is 4 secs. Diagnosis isa) Early compensatedhypovolemic shockb) Early decompensatedhypovolemic shockc) Late compensatedhypovolemic shockd) Late decompensated shockdue to SVT

SURGERY133. Most sensitive screening procedure for CA Prostatea) DREb) PSAc) DRE + PSAd) Endorectal coil MRI with T1W &T2W images

134. Orchiopexy for undescended testes isdone ideally at what age?a) Neonateb) 1-2 yrsc) 5 yrsd) Puberty

135. Polyp not associated with risk of malignancya) Juvenile polypb) FAP

c) Peutz Jeghers syndromed) Juvenile polyposis syndrome

136. Peutz Jeghers polyps present ina) Rectumb) Colonc) Esophagus


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d) Jejunum

137. Renal calculi associated with Proteusinfectiona) Uric acidb) Triple phosphatec) Calcium oxalated) Xanthine

138. Congenital hypertrophic pyloric stenosisassociated witha) Hypokalemic acidosisb) Hypokalemic alkalosisc) Hyperkalemic acidosis

d) Hyperkalemic alkalosis

139. A man with blunt abdominal traumawith h/o pelvic fracture has presented toER. He has passed only few drops of blood per meatus and no urine in thepast 8 hrs. His bladder is palpable per abdomen. Which of the following iscorrect?a) Anuria due to hemorrhagicshockb) Urethral injuryc) Ureteral rupture leading toextravasation of urine inretroperitoneumd) Bladder rupture

140. Sister Mary Joseph nodule associatedwitha) Pancreatic cab) Gastric cac) Colonic cad) Ovarian ca

141. In order to expose the celiac axis, leftrenal artery, superior mesenteric artery


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& abdominal aorta in a case of trauma,which of the following is required?a) Left medial visceral rotationb) Right medial visceral rotationc) Cranial visceral rotationd) Caudal visceral rotation

142. Best prognostic factor for head injurya) Ageb) Mode of injuryc) Glasgow coma scaled) CT finding

143. Most immediate complication of

ileostomy in the post-operative perioda) Obstructionb) Necrosisc) Diarrhead) Prolapse

144. Follicular carcinoma differs fromfollicular adenoma bya) Vascular invasionb) Increased mitotic figuresc) Hurthle cell changed) Lining of columnar & cuboidalcells

145. Hashimotos thyroiditis True are A/Ea) Follicular destructionb) Increase in lymphocytesc) Oncocytic metaplasiad) Orphan Annie eye nuclei

146. Most reliable investigation for Amyloidosisa) Rectal biopsyb) Sigmoidoscopyc) Colonoscopyd) Gingival biopsy


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147. A 60 yr old chronic smoker presentswith painless gross hematuria of 1 dayduration. Investigation of choice to knowthe cause of hematuriaa) USGb) X-ray KUBc) Urine routine microscopyd) Urine cytology for malignantcells

148. In blunt trauma abdomen what shouldbe the approach for doing laparotomy?a) Depends on organ injured

b) Always midlinec) Always transversed) Depends upon type of injury

149. Which of the following is true aboutbranchial anomalies?a) Mostly arises from 2ndbranchial archb) All patients present with stridor at birthc) Branchial cyst is more commonthan sinusd) All branchial sinuses need tobe excised

150. About sternocleidomastoid tumor all aretrue except a) Always associated with breechb) Spontaenous resolution inmost casesc) Two-third have palpable neckmass at birthd) Uncorrected cases developsplagiocephaly


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ORTHO151. A 68 yr old man came with pain andswelling of right knee. Ahlbeck grade 2osteoarthritic changes were found oninvestigation. What is the further management?a) Conservativeb) Arthroscopic washoutc) High tibial osteotomyd) Total knee replacement

152. Which of the following is a pulsatile

tumor?a)Osteosarcomab) Chondrosarcomac) Osteoclastomad) Ewings sarcoma

153. Posterior glenohumeral instability istested bya) Jerk testb) Crank testc) Sulcus testd) Fulcrum test

154. Mineral of the bone isa) Calciteb) Hydroxyapatitec) Calcium oxided) Calcium carbonate

155. 65 yrs old man with H/o of back painsince 3 months. ESR is raised. Markedstiffness on examination. Mild restrictionof chest movements. On X-ray,syndesmophytes are present. Diagnosisisa) Ankylosing spondylitis


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b) Degenerative osteoarthritis of spinec) Ankylosing hyperosteosisd) Lumbar canal stenosis

156. A lady presents with right knee swelling.Aspiration was done in which CPPDcrystals were obtained. Next bestinvestigation isa) ANAb) RFc) CPKd) TSH

OBS & GYNAE157. Pain of ovarian carcinoma is referred toa) Back of thighb) Gluteal regionc) Anterior surface of thighd) Medial surface of thigh

158. A woman 35 years of age with primary infertility with CA-

125 level 90 iu. She has bilateralpalpable mass. USG shows mass inpelvis. Diagnosis may bea) Ovarian CAb) TBc) Endometriomad) Borderline ovarian tumor (palpable mass+three times CA level+it generally occurs 10years younger than that of women with frankly malignantovarian cancer)

159. Causes of primary amenorrhea are A/Ea) Rokitansky syndromeb) Sheehan syndromec) Kallman syndromed) Turner syndrome


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160. Test for ovarian reservea) LHb) LH/FSH ratioc) FSHd) Estradiol

161. Clomiphene citrate True statement is all excepta) Euclomiphene is antiestrogenicb) Pregnancy rate is 3 times ascompared to placeboc) Incidence of twins is 5-6%d) It has been shown to increasefertility in oligospermic males

162. At what gestational age should apregnancy with cholestasis of pregnancy be terminated?a) 34 weeksb) 36 weeksc) 38 weeksd) 40 weeks(not to be continued beyond 37 weeks)

163. A lady with placenta previa delivered ababy. She had excessive bleeding. After resuscitation most likely complication isa) Galactorrhoeab) Diabetes insipidusc) Loss of menstruationd) Cushings syndrome

164. Which of the following treatments for menorrhagia is not supported byevidence?a) Tranexemic acidb) Ethamsylatec) Combined OCPd) Progesterone


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165. Vaginal delivery can be allowed in A/Ea) Monochorionic monoamniotictwinsb) Mento-anterior c) Extended breechd) Dichorionic twins First vertex,second breech

166. A 35 yr old P3+0 is observed to have CINgrade III on colposcopic biopsy. Bestinitial managementa) Cryosurgeryb) Conizationc) LEEP

d) Hysterectomy

167. Lady undergoes total radicalhysterectomy for Stage Ib Ca Cervix. Itis found that Ca extends to lower part of body of uterus and upper part of cervix.Next step of managementa) Chemotherapyb) Radiotherapyc) Chemoradiotherapyd) Follow-up

168. All are seen in gestational diabetesexcepta) Previous macrosomic babyb) Obesityc) Malformationsd) Polyhydramnios

169. A pregnant female at 35 wks of pregnancy is diagnosed with SLE.Drugs that can be used to treat are A/ECorticosteroidsb) Sulphasalazinec) Methotrexated) Hydroxychloroquine


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170. Ideal contraceptive for lactating mothersa) Barrier methodb) Combined OCPc) Lactational amenorrhoead) Progesterone only pills

171. The presence of increased levels of which of the following in amniotic fluid isan indicator of open neural tube defectin the fetus?a) Phosphatidylesteraseb) Acetylcholinesterasec) Pseudocholinesterase

d) Butyrylcholinesterase

172. A pregnant lady had no complaints butmild cervical lymphadenopathy in 1sttrimester. She was prescribedspiramycin but she was non compliant.Baby was born with hydrocephalus &intracerebral calcification. Which of these is likely causea) Toxoplasmosisb) CMVc) Cryptococcusd) Rubella

OPHTHAL173. Which of the following does NOTScavenger of free radicals in the lens?

a) Vit Ab) Vit Cc) Vit Ed) Catalase

174. Highest refractive indexa) Cornea


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b) Anterior surface of lensc) Posterior surface of lensd) Centre of lens

175. Mucopolysaccharide hyaluronic acid ispresent ina) Aqueous humor b) Vitreous humor c) Lensd) Cornea

176. All are important causes of childhoodblindness in India except?a) Glaucoma

b) Congenital dacryocystitisc) Malnutritiond) Ophthalmia neonatorum

177. A young male presents with h/ounilateral progressive proptosis for many years. Swelling is increased onbending forward and compressible,USGshows retrobulbar echogenicity. What isthe diagnosis?a) Neurofibromatosisb) Orbital varixc) Orbital A-V fistulad) Orbital encephalocele

178. Which of the following ocular conditionsis autosomal dominant in inheritance?a) Best diseaseb) Gyrate atrophyc) Lawrence-Moon-Biedelsyndromed) Bassen Kornzweig disease

ENT


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179. Most common site for CSF rhinorrhoeaa) Frontal sinusb) Ethmoidal sinusc) Tegmen tympanid) Maxillary sinus

180. A case of Bells palsy presents on day 3.Which of the following is the appropriatemanagement?a) Oral steroids aloneb) Oral steroids + antiviralacyclovir c) Acyclovir + amantadined) Intralabyrinthine steroids

181. Endolymph in inner ear produced bya) Phalangeal cellsb) Stria vascularisc) Lamina spiralis ossead) Basilar membrane

182. Extrinsic membranes of larynx are A/Ea) Cricothyroidb) Thyrohyoidc) Hyoepiglotticd) Cricotracheal

183. Infection of CNS spreads in inner ear througha) Cochlear aqueductb) Endolymphatic sacc) Vestibular aqueductd) Hyrtle fissure

SKIN184. Which of the following is NOT a primarycutaneous disease?a) Reiters syndrome


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b) Bowens diseasec) Psoriasisd) Lichen planus

185. 25 yr old male having fever & malaisesince 2 weeks, arthritis of ankle joint anderythematous nodules over the shin.Diagnosis isa) Erythema nodosumb) Hensens diseasec) Weber-Christian diseased) Urticarial vasculitis(till proved otherwise)

ANESTHESIA186. The volatility of an anesthetic agent isdirectly proportional to lowering the flowin the portal vein. Portal flow ismaximally reduced bya) Ether b) Halothanec) Isofluraned) Enflurane

187. A young boy has sickle cell trait. whichof the following anaesthesia iscontraindicated?a) IV regional anaesthesiab) Brachial plexus block bysuraclavicular approachc) Brachial plexus block by

infraclavicular approachd) Brachial plexus block byaxillary approach(IVRA is contraindicated in homozygous sickle cell disease but itis not contraindicated in heterozygous sickle cell disease(trait).But still we have to avoid IVRA in trait too.)


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188. Methemoglobinemia caused bya) Procaineb) Prilocainec) Bupivacained) Lignocaine

RADIO189. A 48 yr old woman comes with b/lprogressive weakness of both lower limbs, spasticity & mild impairment of respiratory movements. MRI shows anintradural mid-dorsal midline enhancing

lesion. What is the diagnosis?a) Intradural lipomab) Meningiomac) Neuroenteric cystd) Dermoid cyst

190. A patient brought in unconscious statewith external injuries. CT is normal withno midline shift and ventricles arenormal. Multiple small hemorhages areseen at the base of the brain. Diagnosisisa) Subarachnoid hemorrhageb) Diffuse axonal injuriesc) Concussiond) Contusion

191. Investigation of choice for a lesion of temporal bone

a) CTb) MRIc) USGd) Plain X-ray

192. Which of the following feature of thyroidnodule on usg is not sugestive of


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malignancy?a) Hyperechogenesityb) Hypoechogenesityc) Non-homogenousd) Microcalcification

193. Radiological features of left ventricular failure are all excepta) Oligemic lung fieldsb) Increased flow in upper lobeveinsc) Cardiomegalyd) Kerley B-lines

194. Characteristic radiological feature of fibrous dysplasiaa) Thickened bone matrixb) Cortical erosionc) Ground glass appearanced) Bone enlargement

PSYCHIATRY195. Naltrexone is used in opioiddependence toa)Prevent respiratory depressionb) Treat withdrawl symptomsc) Prevent relapsed) Detoxification of opioidoverdose

196. Drug of choice in OCD

a) Fluoxetineb) Imipraminec) Alprazolamd) Chlorpromazine

197. 3 yr old girl has delayed devolpmentalmilestone, delayed speech, difficulty in


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concentrating on studies, plays withherself & does not make friends.Diagnosis isa) Autismb) ADHDc) Specific learning disorder d) Mental retardation

198. Most common substance abuse in Indiaa) Tobaccob) Cannabisc) Alcohold) Opium

199. A young lady presents with repeatedepisodes of excessive eating followedby purging by use of laxatives. What isthe diagnosis?a) Binge eatingb) Bulimia nervosac) Schizophreniad) Anorexia nervosa

200.mechanism of acute rheumatic fever a)cross reactivity with exogenous antigenb)innocent bystander effectc)d)

AIIMS May 2010 Solution

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