Advanced Materials...

Scientific & Engineering Challenges

8-11 May 2016

University House at the WoodwardLevel 10, Melbourne Law School

185 Pelham Street, Carlton

A celebration of over 30 years of collaboration between Australia and Japan in Materials Science and Engineering

Introduction to the Conference

The Particulate Fluids Processing Centre (PFPC) is pleased to host this special conference on Advanced Materials…Scientific & Engineering Challenges.

In 2015, our principal collaborator in Japan, Professor Toyoki Kunitake, was awarded the prestigious Kyoto Prize (http://www.inamori-f.or.jp/e_kp_out_out.html). We wish to acknowledge his award and further consolidate our Australia-Japan Collaborations and A-J Conferences by presenting this event in his honour here at the University of Melbourne.

Professor Kunitake brings significant new perspectives in the development of controlled molecular architectures for new materials for emerging technologies such as energy conversion and storage and biodelivery therapies for emerging chronic diseases. These perspectives, developed over more than 30 years were central to the award of the International Kyoto Prize to Professor Kunitake and the recognition of their future value in both emerging and developing economies.

The Conference also acknowledges Professor Kazue Kurihara, awardee of the Society of Japanese Women Scientists Merit Award 2014. In addition to her own strong research contributions in Advanced Materials, Professor Kurihara enables an entree via the Advanced Institute for Materials Research (AIMR) at Tohoku University through which opportunities identified at the conference can become centrepieces for new, and invigorated, Australia/Japan research partnerships.

The conference, held over two and a half days at the University of Melbourne will also consist of invited presentations from major Japanese scientists from top-tier institutions. The Conference will not only recognise the seminal contributions of Professors Kunitake and Kurihara to the field of advanced materials science and engineering but will also serve as a catalyst to leading Australian researchers to further develop their own agendas targeting engineering solutions for sustainable futures.

The meeting will also celebrate the supportive collaboration between Japanese and Australian researchers in advanced materials research that has persisted for over 30 years. The Australia-Japan collaborations and the Australia-Japan Symposium (a biennial joint venture between the Colloid and Surface Science Divisions of the RACI and the Chemical Society of Japan) were first hosted in Japan by Professor Toyoki Kunitake and Professor Kazue Kurihara.

We believe that the field of advanced materials is an important area for future technology advances and that this conference allows the opportunity to bring two of the leaders in the field in Japan together with internationally renowned scientists and engineers in Australia. This activity will enhance our engagement with world leading research and foster stronger ties with our research and education partners in Japan.

Professor Tom Healy, Professor Neil Furlong, Professor Peter Scales, Professor Geoff Stevens, Dr Michelle de Silva

1

17:00

19:00

9:00

Professor P

eter Scales

PFPC

, The

 University

 of M

elbo

urne

Welcome

9:05

Professor N

eil Furlong

PFPC

, The

 University

 of M

elbo

urne

Introd

uctio

n to Australia‐Ja

pan Re

latio

nship

9:15

Professor T

oyoki Kun

itake

Kyushu

 University

, Presid

ent o

f Kita

kyushu

 Fou

ndation for 

Advancem

ent Ind

ustry, Scien

ce and

 Techn

ology

Synthe

tic Bilayer M

embrane and Giant N

anom

embrane

10:00

10:30Professor K

azuh

ito Hashimoto

Presiden

t, National Institute for M

aterials Science (NIM

S)Ch

allenges/Prio

rities in Japan arou

nd Advanced Materials Science and 

Engine

ering

11:00Professor F

rank

 Caruso

PFPC

, The

 University

 of M

elbo

urne

Mod

ulating Biological Respo

nses th

rough Interfacial M

aterials En

gine

ering

11:30Professor E

rica Wanless

University

 of N

ewcastle

Polymer Latex Stabilised

 Liquid Marbles: Exten

ding

 the De

sign Ru

les

12:00Professor A

tsushi M

uram

atsu

Director, IMRA

M, Toh

oku University

Recent Research Tren

d of Nanop

articulate Ad

vanced

 Fun

ctional M

aterials 

in IM

RAM, Toh

oku University

12:30

12:30

14:00Professor K

atsuhiko

 Arig

aWorld Premier Internatio

nal (WPI) R

esearch Ce

nter fo

r Materials Nanoarchitecton

ics (MAN

A), N

IMS

World Stupide

st App

roach

Can we op

erate molecular m

achine

s by ou

r hands?

Hand

‐Ope

ratin

g Nanotechn

ology:

14:30Assoc Professor A

ndrea O'Con

nor

PFPC

, The

 University

 of M

elbo

urne

Biom

aterials to Driv

e Outcomes in

 Cell Culture and

 Tiss

ue Engineerin

g

15:00Professor V

ipul Bansal

RMIT University

Biom

imetic Nanozym

e Sensors: From M

olecules to

 Bacteria

 to Cancer C

ell 

Detection

15:30

16:00Professor S

imon

 Biggs

The University

 of Q

ueen

sland

Functio

nal Particles &

 Microcapsules

16:30Assoc Professor C

athy

 McN

amee

Shinshu University

Prop

ertie

s of Langm

uir M

onolayers o

f Polym

er Particles a

t Air/Aq

ueou

s Interfaces

17:00Professor V

icki Che

nUniversity

 of N

ew Sou

th W

ales

Metal Organic Framew

ork Nanocom

posite Mem

branes fo

r Gas Sep

aration

17:30

Sund

ay 8th M

ayWelcome Mixer ‐ Th

e Lincoln, 91 Cardigan

 Street, Carlton

 VIC 305

3Provost D

inne

r ‐ invitatio

n on

ly

Session Ch

air: Neil Furlong

Session Ch

air: Ge

off S

tevens

Session Ch

air:

Rac

hel C

arus

o 

Session Ch

air: P

eter

Sca

les

Mon

day 9th May

Coffe

e

Lunch

Coffe

e

Wom

en's Lunch ‐ invita

tion on

lySpon

sored by

 CSIRO

 Future Indu

strie

s and

 CSIRO

 Ene

rgy

 West R

oom, U

niversity

 Hou

se at W

oodw

ard 

Mixer ‐ University

 Hou

se at W

oodw

ard

Conference Program

2

9:00

Professor K

azue

 Kurihara

WPI‐AIM

R (Advanced Institu

te fo

r Materials Re

search), Institu

te 

of M

ultid

isciplinary Re

search fo

r Advanced Materials (IM

RAM), 

Toho

ku University

Developm

ent o

f Surface Forces M

easuremen

t for M

aterials Science

9:30

Professor K

ohei Uosaki

Director, G

lobal Research Ce

nter fo

r Enviro

nmen

t and

 Ene

rgy 

based on

 Nanom

aterials Science (GRE

EN), NIM

SNovel Electrocatalyst fo

r Oxygen Re

duction Re

actio

n‐ T

heoretical and

 Experim

ental Investig

ations ‐

10:00Dr Cara Do

herty

CSIRO

Adaptiv

e Po

rous M

aterials for D

evice Fabrication

10:30

11:00Professor S

andra Ke

ntish

PFPC

, The

 University

 of M

elbo

urne

Water Permeatio

n through Po

lymeric M

embranes

11:30Professor A

tsushi Takahara

Institu

te fo

r Materials Ch

emistry and

 Engineerin

g, Kyushu 

University

Characterization and Surface Prop

ertie

s of Immob

ilized Po

lyelectrolyte 

Brushe

s in Aq

ueou

s Enviro

nmen

t12

:00Dr Antho

ny Stickland

PFPC

, The

 University

 of M

elbo

urne

Suspen

sion Yielding

 is Not Stressful

12:30

13:30Assist P

rofessor Toshiki Saw

ada

Tokyo Institu

te of T

echn

ology

Constructio

n of Regularly Assem

bled

 Structures C

ompo

sed of Liquid 

Crystalline

 Filamen

tous Viru

ses

14:00Assoc Professor S

higeno

ri Fujikaw

a International Institute for C

arbo

n Neu

tral Ene

rgy Re

search (W

PI‐

I2CN

ER), Kyushu

 University

Gas S

eparation by

 a Free‐Standing

 and

 Nanom

eter‐Thick M

embrane

14:30Assoc Professor B

enjamin Thierry

University

 of Sou

th Australia

Solid

‐State Biosensing toward Intraope

rativ

e Diagno

stics

15:00

15:30Assist P

rofessor M

otoh

iro Kasuya

IMRA

M, Toh

oku University

Characterization of Electrode

‐Electrolyte Interfaces  U

sing Electroche

mical 

Surface Forces App

aratus

16:00Professor R

aymon

d Da

gastine

PFPC

, The

 University

 of M

elbo

urne

Nano‐Scale Prop

ertie

s of D

rops, B

ubbles and

 Microcapsules in

 Em

ulsio

ns, Foams a

nd Encapsulated System

s16

:30Prof Dr R

affaele Mezzenga

ETH Zurich

Self‐Assembly of Amyloid Fibrils in

 One

, Two and Three Dimen

sions: From 

Fund

amen

tals to App

lications

19:00

Tuesda

y 10

th M

ay

Coffe

e

Session Ch

air: Pa

trick Ha

rtley

Session Ch

air: Sand

ra Ken

tish

Lunch

Coffe

e

Conferen

ce Dinne

r ‐ University

 Hou

se at W

oodw

ard

Session Ch

air: Erica Wan

less

Session Ch

air: Simon

 Biggs

Conference Program

3

Conference Program

9:00

Assoc Professor R

ache

l Caruso

PFPC

, The

 University

 of M

elbo

urne

/CSIRO

Porous M

aterials for E

nergy and Environm

ental A

pplications

9:30

Professor G

regory W

arr

The University

 of Sydne

yEngine

ering Nanostructure in

 Ionic Liqu

ids a

nd Deep Eutectic Solvents

10:00Assoc Professor T

etsushi Taguchi

Bioadh

esive Materials Techno

logy Cen

ter (BM

TC), NIM

SRo

bust Sealing Strength of H

ydroph

obically‐m

odified

, Alaska Po

llock‐

deriv

ed Gelatin‐based

 Biode

gradable Sealant Und

er W

et Con

ditio

n

10:30

11:00Professor M

att T

rau

The University

 of Q

ueen

sland

TBC

11:30Assoc Professor S

ally Gras

PFPC

, The

 University

 of M

elbo

urne

Functio

nal Pep

tides and

 Soft C

omplex M

aterials

12:00Professor B

enjamin Boyd

Mon

ash Institu

te of P

harm

aceu

tical Scien

ces

Nanostructure Formation at Polym

er‐Surfactant Interfaces –

 Opp

ortunitie

s for N

ew Stim

uli Respo

nsive De

livery System

s12

:30

13:30Professor P

eter Scales (Ch

air)

Director, PFPC, The

 University

 of M

elbo

urne

Professor K

atsuhiko

 Arig

aWPI‐M

ANA, NIM

SProfessor S

uresh K Bh

argava

RMIT University

Professor C

alum

 Drummon

dRM

IT University

Dr Patrick Ha

rtley

CSIRO

Professor T

oyoki Kun

itake

Kyushu

 University

Assoc Professor A

ndrea O'Con

nor

PFPC

, The

 University

 of M

elbo

urne

15:00Professor T

om Healy

Concluding

 remarks

Pane

l Disc

ussio

n, con

firmed

 mem

bers:

Wed

nesday 11th May

Coffe

e

Lunch

Session Ch

air: Ra

y Da

gastine

Session Ch

air: An

drea

 O'Con

nor

4

Synthetic Bilayer Membrane and Giant Nanomembrane

Toyoki KunitakeFAIS and Kyushu University

2-1 Hibikino, Wakamatsu-ku,Kitakyushu 808-0135, JapanE-mail: kunitake@ruby.ocn.ne.jp

A totally synthetic bilayer membrane was first reported in 1977, as aqueous dispersion of dialkylammonium salts and this finding was then extended to other related amphiphiles with one to four hydrophobic chains. Such spontaneous bilayer formation is based on the interfacial stability of membrane surface and 2D alignment of component molecules. Subsequently, bilayer formation was realized even in organic solvents from fluorocarbon compounds. Thus, bilayer formation is shown to be a broad physicochemical concept. More recently, we developed giant nanomembranes from thermosetting resins and metal oxides. They are robust, flexible, defect-free and nanometer-thick with huge aspect ratios (size/thickness) of over one million. Finally, the technological potential of these molecular systems are discussed.

Abstracts

5

Toyoki KUNITAKE, Dr., Prof.

Affiliation: Kitakyushu Foundation for the Advancement of Industry, Science and Technology (FAIS); Kyushu University

Address(FAIS): 2-1 Hibikino, Wakamatsu-ku, Kitakyushu 808-0135, JapanTel: +81-93-695-3111; Fax: +81-93-695-3010E-mail: kunitake@ruby.ocn.ne.jp

Major Fields: Supramolecular Chemistry, Molecular Organization, and Ultrathin Film

Biography: • Postdoctoral Fellow, Department of Chemistry, California Institute of

Technology, 1962-1963 (with Prof. C.G. Nieman). • Associate Professor(1963-1974) and Professor(1974-1999),Faculty of

Engineering, Kyushu University,.• Dean, Faculty of Engineering, Kyushu University, 1992-1994.• Professor and Vice President, University of Kitakyushu,1999–2008• Group Director, Frontier Research System, RIKEN, 1999-2007• President, Kitakyushu Foundation for Advancement of Industry, Science and

Technology, 2009-present.• CTO, NanoMembrane Technologies, Ltd. 2007-present.• University Professor, Kyushu University, 2015-present.

6

Challenges/Priorities in Japan around Advanced Materials Science and

Engineering

Kazuhito HashimotoNational Institute for Materials Science1-2-1 Sengen, Tsukuba 305-0047, Japan

E-mail: HASHIMOTO.Kazuhito@nims.go.jp

Today, social expectations for science and technology are greater than ever, and the government considers the promotion of science and technology to be one of its paramount policies. As many people agree, Japan’s industry is leading the world in the development of new materials and functional materials, and Japan’s materials research that supports the industry is also world-class. Under such circumstances, expectations are high for National Institute for Materials Science (NIMS) to lead advanced materials research and play an active role in providing a foundation for strengthening the R&D competitiveness of Japan.

To meet these expectations, we enhance our “mediating function,” aiming to accelerate the return of research accomplishments to society. Under the principle that “the true value of materials is in their use,” we will build a close relationship with the industrial sector and encourage researchers to be actively involved in the application of their research results to society. We will make continuous efforts to transfer our results to the industrial sector for use, and to become a hub to facilitate product R&D in academia and the industrial sector.

We will also continue to collaborate with organizations specialized in different fields. In particular, promotion of joint research with the information and communications technology (ICT) sector is an urgent issue, as is conformity with the Japanese Government’s Fifth Science and Technology Basic Plan starting this year, which states to “strongly undertake a series of initiatives to realize the future vision of super-smart society (Society 5.0), which is an elaborate fusion of cyberspace and physical space (the real world).” NIMS founded the Center for Materials Research by Information Integration where initiatives have already been taken to fuse materials research with data science.

Engaging in these endeavors, we will further grow as an organization contributing to Japan and international community.

7

Kazuhito Hashimoto, President

Affiliation: National Institute for Materials Science (NIMS)

Address: 1-2-1 Sengen, Tsukuba, Ibaraki 305-0047, JapanTel: +81-29-859-2001; Fax: +81-29-859-2008E-mail: HASHIMOTO.Kazuhito@nims.go.jp

Major Fields: Physical Chemistry, Material Science

Biography: 1985 Doc. Science, Chemistry. The University of Tokyo1980-1984 Technical Associate, Institute for Molecular Science, Okazaki1984-1989 Research Associate, Institute for Molecular Science, Okazaki1989-1991 Lecturer, Department of Applied Chemistry, The University of Tokyo1991-1997 Associate Professor, Department of Applied Chemistry, The

University of Tokyo1997-2004 Professor, Research Center for Advanced Science and Technology,

The University of Tokyo2004-2016 Professor, Department of Applied Chemistry, The University of

Tokyo20016- President, National Institute for Materials Science

8

Modulating Biological Responses through Interfacial Materials Engineering

Frank CarusoARC Centre of Excellence in Convergent Bio-Nano Science and Technology, and the

Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria, 3010, AustraliaE-mail: fcaruso@unimelb.edu.au

The development of rapid and versatile coating strategies for interface and particle engineering is of immense scientific interest. Recently, we reported the rapid formation of thin films comprised of metal–phenolic networks (MPNs) on various substrates by simply mixing natural polyphenols and metal ions. This coating technique is substrate independent (covering organic, inorganic and biological substrates) and has been used for the assembly of capsules by coating particles and then removing the coated templates. It will be shown that a range of polyphenols and a library of metal ions are suitable in forming MPNs for film and capsule engineering. The MPN films and capsules are stable at physiological pH but degrade at acidic pH, making them of interest for intracellular release of therapeutics. By altering the metal ions, different functions can be incorporated in the MPN materials, ranging from fluorescence to MRI and catalytic capabilities. Furthermore, synthetic polymer-phenol conjugates have been used as building materials for control over the biofouling properties of the MPN materials. The ease and scalability of the assembly process, combined with pH responsiveness, negligible cytotoxicity and tunable properties, provides a new avenue for functional interface engineering, and makes these MPNs potential candidates for biomedical and environmental applications.

9

Frank Caruso, Professor and ARC Australian Laureate Fellow

Affiliation: ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, and the Department of Chemical and Biomolecular Engineering, The University of Melbourne

Address: Building 165, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria, 3010, Australia Tel: +61-3-8344-3461 E-mail: fcaruso@unimelb.edu.au

Major Fields: Materials science, nanotechnology, self-assembly

Biography:2002-present The University of Melbourne, Australia

Professor, ARC Australian Laureate Fellow (2012-) Deputy Director, ARC Centre of Excellence in Convergent Bio-Nano Science and Technology (2014-)

2013-2014 Bionics Institute, Australia Honorary Research Fellow

2003-2010 Centre for Nanoscience and Nanotechnology, The University of Melbourne Founder and Director

1997-2002 Max Planck Institute of Colloids and Interface, Germany Group Leader & Research Scientist (1999-2002) Alexander von Humboldt Research Fellow (1997-1998)

1994-1996 CSIRO, Division of Chemicals and Polymers, Australia Postdoctoral Fellow

1990-1993 Ph.D., Physical Chemistry (The University of Melbourne, Australia)1986-1989 B.Sc. (Honours), Physical Chemistry, First Class (The University of

Melbourne, Australia)

10

Polymer Latex Stabilised Liquid Marbles: Extending the Design Rules

Erica WanlessDiscipline of ChemistryUniversity of Newcastle

Callaghan, NSW 2308, AustraliaE-mail: Erica.wanless@newcastle.edu.au

Aqueous liquid marbles are water droplets stabilised by hydrophobic particles adsorbed at the water-air interface. Polymer colloids offer certain advantages here since a stimulus response to trigger payload release,1 or solvent annealing to form microcapsules,2 can be included in the particle design. Liquid marbles have been formed via a traditional rolling method using a submicrometre-sized polystyrene latex carrying poly[2-(diethylamino)ethyl methacrylate] hairs. The polybasic hairs on the particles are hydrophilic and cationic in acidic solution and hydrophobic in basic solution.1,2 The interactions and stability of two pendent liquid marbles, or a liquid marble (or annealed capsule) with a neighbouring water droplet have been investigated by high speed video.3 These observations can inform the upscale and processing of bulk liquid marble formulations.

We have also been applying a new electrostatic formation route4 to polymer latex stabilised liquid marbles.5 Observations on the influence of drop and particle size on this process will be discussed by bringing an earthed water drop of volume 3 – 7 μL into proximity with a bed of highly-charged polystyrene particles of diameter 22 – 153 μm. Under certain conditions the particles jump to and coat the drop, producing a particle-liquid aggregate that dropped to the bed surface in the form of either a stable liquid marble or a particle-stabilised sessile drop. Formation of stable marbles appeared to occur more easily for smaller drops and larger particles, and thus it is clear that the ‘rules’ for electrostatic formation of liquid marbles are quite different for those for conventional direct-contact formation.

References1. S. Fujii, M. Suzaki, S.P. Armes, D. Dupin, S. Hamasaki, K. Aono, Y. Nakamura, Langmuir

27, 8067-8074 (2011). DOI: 10.1021/la201317b.2. K. Ueno, S. Hamasaki, E.J. Wanless, Y. Nakamura, S. Fujii, Langmuir 30, 3051-3059

(2014). DOI: 10.1021/la5003435.3. K. Ueno, G. Bournival, E.J. Wanless, S. Nakayama, E.C. Giakoumatos, Y. Nakamura, S.

Fujii, Soft Matter, 11, 7728-7738 (2015). DOI: 10.1039/c5sm01584g.4. K. R. Liyanaarachchi, P. M. Ireland, G. B. Webber and K. P. Galvin, Appl. Phys. Lett.,

2013, 103.5. P. M. Ireland, M. Noda, E. Jarrett, S. Fujii, Y. Nakamura, E.J. Wanless, G.B. Webber, Soft

Matter, submitted April 2016.

11

Erica Wanless, Prof.

Affiliations: Priority Research Centre for Advanced Particle Processing and Transport, School of Environmental and Life Sciences, Newcastle Institute of Energy & Resources (NIER), University of Newcastle.

Address: NIER Building C, University of Newcastle, University Drive, Callaghan, NSW 2308, AustraliaTel: +61-2-4033-9355E-mail: erica.wanless@newcastle.edu.au

Major Fields: Adsorption and behaviour of surfactants, polymers, polymer colloids and mineral particles at interfaces.

Biography: 1990 BSc(Hons) (Australian National University)1995 PhD (Australian National University)1995-1996 Postdoctoral Researcher (University of Otago, New Zealand)1996-1999 Associate Lecturer (University of Newcastle, Australia)2000-2003 Lecturer (University of Newcastle, Australia) 2003 Visiting Research Fellow (University of Sussex, UK)2004-2007 Senior Lecturer (University of Newcastle, Australia)2007-2013 Associate Professor (University of Newcastle, Australia) 2008 Visiting Research Fellow (Universities of Sheffield & Durham, UK) 2012 JSPS Fellow (Osaka Institute of Technology, Osaka)2013-present Professor (University of Newcastle, Australia) 2015 Visiting Research Fellow (Technical University of Berlin, Germany)

12

Recent Research Trend of Nanoparticulate Advanced Functional Materials in IMRAM, Tohoku Univ.

Atsushi MURAMATSU, Prof., Dr.

mura@tagen.tohoku.ac.jp IMRAM, Tohoku Univ. Sendai 980-8577, Japan

http://res.tagen.tohoku.ac.jp/mura/ Phone +81-22-217-5163 FAX +81-22-217-5165

Recent Research Trend will be presented for nanoparticulate advanced functional ceramics materials, in particular, in our laboratory. Here, we will focus our attention on transparent conductive oxides (TCO). Among TCO, indium-tin-oxides (ITO) thin film is generally prepared by the sputtering process with ITO target, but only 20% of ITO yielded from the target is deposited on the substrate. Namely, about 80% ITO is exhausted by the deposition elsewhere far from the substrate. The recycling process of indium is limited so that ca 20% ITO of the starting material is lost without any recovery. Even if the recycling of ITO has been carried out in this process, we should prepare ITO target of 5 times more than apparent use of ITO on film. If we change it to printing process from the sputtering, the reduction in ITO use is expected as ca. 50%, considering the increase in film thickness by printing. Our target technology also includes ITO nanoink for the project. As a result, monodispersed ITO nanoparticles (NPs) with a cubic shape were fabricated by using quaternary ammonium hydroxide-assisted metal hydroxide organogels. These NPs have perfect uniformity in size with beautiful shape, and perfect single crystalline structure including Sn. As we were attempted to make thin film with ITO nanoink, it was successfully fabricated below 200 nm in thickness and the resistivity was drastically decreased below 1.0 x 10-3 ohm cm after heat treatments. GZO nanoink as substitute of ITO has also been developed.

13

Atsushi MURAMATSU, Dr., Prof.

Affiliation: Institute of Multidisciplinary Research for Advanced Materials (IMRAM, or Tagen-Ken in Japanese), Tohoku University

Address: Katahira 2-1-1, Aoba-ku, Sendai 980-8577, JapanTel: +81-22-217-5200; Fax: +81-22-217-5165E-mail: mura@tohoku.ac.jp

Major Fields: Nanomaterials, Nanoink, Heterogeneous Catalysis, and Energy Materials

Biography: 1985 Master Degree (The University of Tokyo)1988 Doctor Degree (The University of Tokyo)1988-1993 Research Associate (Tohoku University)1993-1995 Lecturer (Tohoku University)1995-2001 Associate Professor (Tohoku University)2001- Professor (Tohoku University)2015- Director of IMRAM, Tohoku Univ.

14

World Stupidest Approach

Can we operate molecular machines by our hands?

Hand-Operating Nanotechnology:

Katsuhiko Ariga WPI-MANA, Natl. Inst. Mater. Sci.

1-1 Namiki, Tsukuba 305-0044, JapanE-mail: ARIGA.Katsuhiko@nims.go.jp

Functional materials have been wisely constructed via bottom-up approaches as seen in preparation of molecular and nano patterns and complexes, organized nanostructures, and function materials. However, novel concepts to bridge nano (molecular) structures and bulk systems now becomes crucial in order to control real nano and molecular functions from our visible macroscopic worlds.

Here we propose a novel methodology “hand-operating nanotechnology” where molecular orientation, organization and even functions in nanometer-scale can be operated by our macroscopic (hand) operation. This concept can be realized at dynamic two-dimensional medium such as thin films at the air-water interface because this medium possess both features of bulk and molecular dimension. For example, we successfully manipulated molecular machines at the air-water interface upon bulk (10-100 cm size) motion of the entire monolayer and realized “capture and release” of aqueous guest molecules using molecular machine, steroid cyclophane (see Figure). In addition, mechanically controlled chiral recognition of amino acid and discrimination of nucleosides by the supramolecular monolayer was successfully demonstrated. The concept has been also applied to indicator-displacement assay for sensor usage. These examples demonstrate our new concept, manual nanotechnology so-called, hand-operating nanotechnology, with which we can manually control nano/molecular phenomena and functions by macroscopic mechanical force such as hand motions. Using hands for functional operation would be most environmentally friendly and least energy consuming technology.

15

Katsuhiko ARIGA, Dr., Prof.

Affiliation: World Premier International (WPI) Research Center for Materials Nanoarchi-tectonics (MANA), National Institute for Materials Science (NIMS)

Address: 1-1 Namiki, Tsukuba, Ibaraki 305-0044, JapanTel: +81-29-860-4597; Fax: +81-29-860-4832E-mail: ARIGA.Katsuhiko@nims.go.jp

Major Fields: Supramolecular Chemistry, Surface Science, and Nanomaterials

Biography: 1987 Master Degree (Tokyo Institute of Technology)1990 Doctor Degree (Tokyo Institute of Technology)1987-1992 Assistant Professor (Tokyo Institute of Technology)1990-1992 Postdoctoral Researcher (University of Texas at Austin)1992-1998 JST Group Leader (Supermolecules Project) and CREST Researcher1998-2001 Associate Professor (Nara Institute of Science and Technology)2001-2003 JST Group Leader (Nanospace Project)2004- Director of Supermolecules Group, NIMS2007- Principal Investigator, MANA, NIMS, 2008- Visiting Professor (Tokyo University of Science)2011- Visiting Professor (Warsaw University of Technology)

16

Biomaterials to Drive Outcomes in Cell Culture and Tissue Engineering

Andrea O’ConnorDepartment of Chemical and Biomolecular Engineering

The University of Melbourne, Victoria 3010 AustraliaE-mail: a.oconnor@unimelb.edu.au

Biomaterial constructs have been proposed to play many important roles in tissue engineering, including maintaining space for tissue growth, acting as scaffolding for cell attachment and migration, mimicking native tissue microenvironments and delivering bioactive molecules. However, they are not always successful in vivo and can even impede the desired tissue development. Optimal design of biomaterial constructs depends on insights into the complex cell and tissue requirements during tissue regeneration, their interactions with biomaterials and how these change over time during development of tissues. The mechanical properties of cells and tissues are used as a basis for the design of biomaterial constructs for stem cell culture in vitro and tissue engineering of soft vascularised tissues in vivo. Hydrogels, hydrophilic polymer networks that have high water contents, can be fabricated with similar viscoelastic properties to those of native tissues. Highly interconnected macroporosity is introduced into such hydrogels to facilitate molecular and cellular transport as well as vascularisation for tissue engineering. Macroporous hydrogels have been fabricated from natural biopolymers including hyaluronic acid and chitosan using templating, gas foaming and cryogelation strategies to control their elasticities, pore sizes and interconnectivity to suit a range of soft tissues. Antimicrobial properties are conferred on constructs via low toxicity inorganic nanoparticles to combat potential infections and biofilm formation. By combining physical, chemical and biological factors in the design of biomaterial constructs, we aim to enhance the growth rate and quality of cell culture and tissue engineering outcomes.

17

Andrea O’CONNOR, PhD, A/Prof.

Affiliation: Department of Chemical and Biomolecular Engineering, Particulate Fluids Processing Centre (PFPC), The University of Melbourne

Address: Department of Chemical and Biomolecular EngineeringThe University of Melbourne, Victoria 3010 AustraliaE-mail: a.oconnor@unimelb.edu.au

Major Fields: Biomaterials, tissue engineering, porous materials, antimicrobial materials

Biography: 1990 Bachelor of Engineering (Chemical, Hons), University of Melbourne1995 PhD, University of Melbourne1995-1996 Fulbright Postdoctoral Research Fellow, Chemical Engineering, MIT1996 Director, MIT School of Chemical Engineering Practice (USA)1996 Research Fellow, Department of Chemical Engineering, University of

Melbourne 1997 Director, MIT School of Chemical Engineering Practice (Japan)1997-2002 Lecturer, Chemical Engineering, University of Melbourne2003-2009 Senior Lecturer, Chemical and Biomolecular Engineering, Uni. Melbourne2010- Associate Professor, Chemical and Biomolecular Engineering, Uni.

Melbourne2012- Deputy Head, Chemical and Biomolecular Engineering, Uni. Melbourne

18

Biomimetic Nanozyme Sensors: From Molecules to Bacteria to Cancer Cell

Detection

Vipul BansalIan Potter NanoBioSensing Facility, NanoBiotechnology Research Laboratory (NBRL),

School of Science, RMIT University, Melbourne, VIC, 3001, AustraliaE-mail: vipul.bansal@rmit.edu.au

Nanomaterials are well-known for their impressive catalytic activity. However, more recently, a number of nanomaterials are being discovered to behave similar to the traditional biomolecular enzymes such as peroxidase, oxidase, catalase and superoxide dismutase. This biomimetic activity of nanomaterials is establishing ‘nanozymes’ as artificial inorganic enzymes and the research field have just begun to explore this unique property for a range of applications.

Our group has established that by combining nanozyme activity of different nanomaterials (e.g. metals, metal oxides, 2-D dichalcogenides) with certain molecular recognition elements (MREs) such as aptamers and antibodies, the nanozyme activity can be actively modulated.

This control over nanozyme activity of inorganic materials has allowed us to develop new ultrafast, highly sensitive and selective colorimetric nanobiosensors for the detection of a range of analyte molecules. We have shown that this generic biosensing approach can be applied for the detection of a range of analyte molecules relevant to environmental monitoring[1] as well as biomedical and food industries.[2] Our more recent investigations show that the same approach can be adapted for highly specific detection of pathogenic bacteria (with sup-species level specificity), as well as highly sensitive detection of cancer cells. We will discuss some of the recent developments made by our group in this area.[3]

Acknowledgements

V Bansal acknowledges the Australian Research Council for a Future Fellowship (FT140101285) and the support of Ian Potter Foundation in establishing an Ian Potter NanoBioSensing Facility at RMIT University. Shown image is modified version from the reference [2] below.

References[1] T. K. Sharma et al. Aptamer-mediated ‘turn-off/turn-on’ nanozyme activity of gold nanoparticles for kanamycin detection. Chemical Communications 2014, 50, 15856-15859.[2] P. Weerathunge et al. Aptamer-controlled reversible inhibition of gold nanozyme activity for pesticide sensing. Analytical Chemistry 2014, 86, 11937-11941.[3] T. K. Sharma et al. Moving forward in food safety and security through NanoBioSensors: adopt or adapt biosensor technologies? Proteomics 2015, 15, 1680-1692.

19

Vipul BANSAL, Dr., Prof.

Affiliation: Ian Potter NanoBioSensing Facility, NanoBiotechnology Research Laboratory (NBRL)

Address: School of Science, RMIT University, Melbourne, VIC, 3001, AustraliaTel: +61-3-9925-2121; Fax: +61-3-9925-3747E-mail: vipul.bansal@rmit.edu.au

Major Fields: Supramolecular Chemistry, Surface Science, and Nanomaterials

Biography: 2007 Doctor Degree (National Chemical Laboratory India)2007-2008 Postdoctoral Research Fellow (University of Melbourne)2008- Group Leader, NanoBiotechnology Research Laboratory (RMIT University)2008-2009 Tenure Track Fellow (RMIT University)2009-2012 Australian Research Council APD Fellow (RMIT University)2013-2014 Associate Professor (RMIT University)2014-2018 Australian Research Council Future Fellow (RMIT University)2014- Director, Ian Potter NanoBioSensing Facility (RMIT University)2015- Professor (RMIT University)

20

Functional Particles & Microcapsules

Simon BiggsSchool of Chemical Engineering, The University of Queensland, St. Lucia QLD 4072

E-mail: simon.biggs@uq.edu.au

Over the last 5 years within our research group we have developed a number of bespoke microcapsule and particle designs tailored to the characteristics of the material to be encapsulated. In this presentation, examples of core-shell particles for use in electrophoretic display applications as well as semi-permeable and impermeable microcapsules for the encapsulation of large and small molecular weight species will be discussed.

For electrophoretic displays, oil dispersable particles with controlled opacity, density and charge are needed. Using examples from our work, I will show how fine control over particle properties can be achieved and how such syntheses can be scaled up for commercial manufacture.

For semi-permeable capsules, I will show how we can use environment-responsive polymers to manage the permeability of polymer shells built around emulsion droplet precursors. I will also briefly introduce the potential of membrane emulsification techniques to manufacture these capsules on multi-litre scales.

Finally, I will discuss a recently developed method for the preparation of metal-coated emulsion droplets for the long-term retention of small, volatile encapsulated species. I will indicate the key aspects of the synthesis method for such metal shells and demonstrate our ability to control the thickness of the shell deposited on the surface of the droplets and exemplify the release properties of these microcapsules.

21

Professor Simon BIGGSFREng CEng FIChemE FIEAust FRSC

Affiliation: The University of Queensland

Address: Faculty of Engineering, Architecture & Information Technology, Brisbane QLD 4072Tel: 07 3365 3329E-mail: simon.biggs@uq.edu.au

Major Fields: Particle and colloid engineering, formulation, particle design and synthe-sis, particle manufacture

Biography: 1986 BSc (University of Bristol)1990 PhD (University of Bristol)1990-1992 Research Fellow (CNRS, Strasbourg, France)1992-1994 Research Fellow (University of Melbourne, Australia)1994-2002 Lecturer/Senior Lecturer/Associate Professor (University of Newcas-tle, Australia)2002-2014 Professor (University of Leeds, UK)2014- Executive Dean (University of Queensland, Australia)

22

Properties of Langmuir Monolayers of Polymer Particles at Air/Aqueous Interfaces

Cathy McNameeShinshu University

Tokida 3-15-1, Ueda-shi, Nagano-ken 386-8567, Japan E-mail: mcnamee@shinshu-u.ac.jp

Dispersions of liquids or bubbles in liquids can be stabilized by adsorbing particles at the air/liquid or liquid/liquid interface. The effectiveness of the stabilization is affected by the size, number, and type of particles and by the packing density and structures formed by those particles at the interface. The properties of the particle stabilized emulsions in equilibrium are somewhat understood. However, the physical properties of a particle coated interface under non-equilibrium situations is not well understood, e.g., the effect of an external material colliding with a particle stabilized interface on the physical properties is still unclear.

We modeled a particle stabilized bubble that was dispersed in a liquid by creating Langmuir monolayers of polystyrene particles loaded with poly(N,N-dimethylaminoethylmethacrylate) (“PDMA-PS”) at air/aqueous interfaces. We determined the effect of the particle charge and packing density on the forces and physical properties of the monolayers at air/aqueous interfaces, when a particle in the aqueous phase collided with the monolayer. We subsequently studied ways to control the strength of the particle monolayers. The physical properties of the monolayers were investigated using the Monolayer Particle Interaction Apparatus, which measured the surface pressure-area isotherms of the monolayers and the forces between a particle (probe) in the water subphase and the Langmuir monolayer at the air/water interface.

23

Cathy McNamee, Dr.

Affiliation: Faculty of Textile Science and Technology, Shinshu UniversityAddress: Tokida 3-15-1, Ueda 386-8567, JapanTel: +81-268-21-5585E-mail: mcnamee@shinshu-u.ac.jp

Major Fields: Interfacial Science and Colloid Chemistry

Biography: 1997 First Class Honours in Chemistry (The University of Queensland,

Australia)1997-1998 Research student (Kyoto University, Japan)2001 Doctor of Science (Kyoto University, Japan)2002-2003 Alexander von Humboldt Research Fellow (Ulm University,

Germany)2004-2005 Post-doctoral Research Fellow (Lund University, Sweden)2005-2007 JSPS Research Fellow (Kyoto University, Japan) 2007-2008 Post-doctoral Research Fellow (Max Planck Institute for Polymer

Physics, Germany)2008-2012 Assistant professor (Shinshu University, Japan)2012- Associate Professor (Shinshu University, Japan)

24

Metal Organic Framework Nanocomposite Membranes for Gas Separation

Vicki ChenUNESCO Centre for Membrane Science and Technology

School of Chemical EngineeringUniversity of New South Wales

Sydney, NSW 2052E-mail: v.chen@unsw.edu.au

The potential of using metal-organic framework (MOF) material for gas separation has received wide spread interest. However, the challenges to make scaleable MOF devices for industrial applications remain significant. These include but are not limited to poor adhesion between MOFs and potential polymer supports, difficulty in obtaining a thin but stable coating layer, and the aggregation of MOF nanoparticles in the membrane matrix.Currently, our group has been focusing on the synthesis of polymer nanocomposite membranes for gas separation via various approaches including layer-by-layer coating on polymer membrane, blending in membrane matrix, and in-situ crystallization on supporting polymer membrane surfaces. For example, by adding the pre-synthesized ZIF-8, UiO66, and MOF-74 into PEO-PA block copolymer and subsequent of coating the selective layer onto a porous membrane surface, thin nanocomposite membranes exhibited significantly improved CO2 permeance while the CO2/N2 selectivity was relatively unchanged when compared with pure polymer benchmark. Using a novel in situ crystallization technique, a coherent ZIF-8 layer can also be synthesized as a coherent ultrathin layer onto the polymer membrane surfaces using a facile, rapid, one-pot approach. These pure ZIF membranes were showed unusual flexibility as well as one of the highest H2 permeances (60,000 GPU) for molecular sieving ZIF-8 membranes.

25

Professor Vicki Chen

Affiliation: UNESCO Centre for Membrane Science and Technology, School of Chemical Engineering, University of New South Wales (UNSW)

Address: School of Chemical Engineering, University of New South Wales, Sydney NSW 2052Tel: +61-2 9385-4813; Fax: +61-2 9385-5966E-mail: v.chen@unsw.edu.au

Major Fields: Membrane Science and Technology, Water and Wastewater Treatment, Bioseparations, Surface functionalisation, CO2 capture and conversion

Biography: 1983 Bachelor of Science in Chemical Engineering (Massachusetts Institute

of Technology)1988 Ph.D. in Chemical Engineering (University of Minnesota)1988 – 1993 Research Associate UNESCO Centre for Membrane Science and

Technology, 1994 – 1995 Research Fellow, UNESCO Centre for Membrane Science and

Technology1996 – 1999 Lecturer, School of Chemical Engineering, UNSW1999 – 2002 Senior Lecturer, School of Chemical Engineering, UNSW2000 – 2006 Director of Teaching and Learning, School of Chemical Engineering,

UNSW2003 – 2007 Associate Professor, School of Chemical Engineering, UNSW2006 – 2014 Director, UNESCO Centre for Membrane Science and Technology2008 – present Professor, School of Chemical Engineering, UNSW2014 – present Head, School of Chemical Engineering, UNSW

26

Development of Surface Forces Measurement for Materials ScienceKazue Kurihara

IMRAM, Tohoku University2-1-1 Katahira, Aoba-ku, Sendai 980-8577, JAPAN

E-mail: kurihara@tagen.tohoku.ac.jp

Surface forces measurement directly measures surface interactions in liquids as a function of the surface separation with high sensitivity. It is a powerful tool for studying origins of forces operating between molecules and/or surfaces of interest. It also offers a unique, novel surface characterization method, which “monitors surface properties changing from the surface to the bulk (depth profiles)” and provides new insights into surface phenomena. The effective area which this measurement monitors is large, typically 30 μm in diameter, although the resolution of the separation distance is 0.1 nm. Due to these size ranges, the measurement is unique and can connect the mesoscopic phenomena with molecular properties. We have made efforts to extend the scope of this measurement in materials science. This paper summarizes recent developments. The conventional surface forces apparatus (SFA) using the multiple beam interferometry of white light, called the FECO method, to measure the distance between macroscopic surfaces. However, for FECO, the substrate needs to be transparent and atomically smooth mica surfaces are commonly used. In order to remove this restriction, we have recently developed a novel SFA, which is called a twin-path SFA and can study opaque samples such as metals [1]. The small displacement of a surface, the bottom one in this study, was measured by the modified two-beam (twin path) interferometry. It is possible to determine the distance with a resolution of 0.2 nm in the working range of 5 μm. This apparatus can extend the scope of the surface forces measurement. We have constructed a spectroscopic SFA [2, 3] and an electrochemical SFA [4-6]. One major field of the surface forces measurement is shear measurements of confined liquids. Liquids confined in nanometer scale space exhibit quite different properties from those in the bulk. Understanding their properties has important bearing on advanced technologies such as nano-fluidics and tribology. We developed the resonance shear measurement (RSM), which has advantages of high sensitivity to changes in rheological and tribological properties of confined liquids and easy operation [7]. Studies using RSM revealed interesting, previously unknown behavior of confined liquids: (1) the effect of confinement preventing a nematic liquid crystal from the electric field induced orientation [8]; (2) Viscosity of ionic liquids nano-confined between silica surfaces [9, 10]: (3) Viscosity of confined lubricants [11]. Tribological properties of gels have been quantitatively determined, indicating the deformation contribution is the dominant factor in friction [12].

[1] H. Kawai, H. Sakuma, M. Mizukami, T. Abe, Y. Fukao, H. Tajima, K. Kurihara, Rev. Sci. Instrum. 2008, 79, 043701.

[2] D. Fukushi, M. Kasuya, H. Sakuma, K. Kurihara, Chem. Lett. 2011, 40, 776.

[3] Y. Saito, M. Kasuya, K. Kurihara, Chem. Lett., 2012, 41, 1282. [4] T. Kamijo, M. Kasuya, M. Mizukami, K. Kurihara, Chem. Lett.

2011, 40, 674.[5] M. Kasuya, K. Kurihara, Langmuir, 2014, 30(24) 7093.[6] M. Kasuya, T. Sogawa, T. Masuda, T. Kamijo, K. Uosaki, K.

Kurihara, J. Phys. Chem. C, DOI:10.1021/acs.jpcc.5b12683[7] M. Mizukami, K. Kurihara, Rev. Sci. Instrum. 2008, 79, 113705.

[8] S. Nakano, M. Mizukami, K. Kurihara, Soft Matter, 2014, 10(13), 2110.

[9] K. Ueno, M. Kasuya, M. Watanabe, M. Mizukami, K. Kurihara, Phys. Chem. Chem. Phys., 2010, 12, 4066.

[10] F. Federici Canova, H. Matsubara, M. Mizukami, K. Kurihara, A. L. Shluger, Phys. Chem. Chem. Phys., 2014, 16, 8247.

[11] J. Watanabe, M. Mizukami, K. Kurihara, Tribol. Lett., 2014, 56, 501.

[12] H.-Y. Ren, M. Mizukami T. Tanabe, H. Furukawa. K. Kurihara, Soft Matter, 2015, 11, 6192.

27

Kazue KURIHARA, Dr., Prof.

Affiliation: Institute of Multidisciplinary Research for Advanced Materials (IMRAM), World Premier Institute (WPI)-Advanced Institute for Materials Research (AIMR), Tohoku University

Address: 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, JAPANTel: +81-22-217-5673; Fax: +81-22-217-5674E-mail: kurihara@tagen.tohoku.ac.jp

Major Fields: Surface Forces Measurement, Molecular Architecture Chemistry, Nano-technology

Biography: 1976 M. S. in Chemistry, Faculty of Science, Ochanomizu University1979 Ph.D. in Chemistry, Faculty of Engineering, University of Tokyo1979-1983 Research Associate, University of Tokyo1981-1981 Postdoctoral Fellow, Texas A&M University1982-1984 Postdoctoral Fellow, Clarkson University1984-1987 Research Associate, Research Institute for Production Development, (Kyo-

to)1986-1987 Visiting Researcher, Institute for Surface Chemistry, (Stockholm)1987-1992 Group Leader, ERATO Kunitake Molecular Architecture Project, Research Development Corporation of Japan1992-1997 Associate Professor, School of Engineering, Nagoya University1997-2001 Professor, Institute for Chemical Reaction Science, Tohoku University2001-Present Professor, IMRAM, Tohoku University2005-Present Science Board, Particulate Fluids Processing Centre, The University of

Melbourne2005-Present Member, Science Council of Japan2010-Present Professor, WPI-AIMR, Tohoku University2011-2014 Chair, Chemistry Committee, Science Council of Japan2012-Present Project Leader, Ultra-low Friction Technology Area, Tohoku Innovative

Materials Technology Initiatives for Reconstruction, Tohoku University2012-2015 President, International Association of Colloid and Interface Scientists2015-Present Member, Council for Science and Technology, MEXT2016-Present Research Professor, Tohoku University

Prof. Kurihara is a current or past member of editorial boards including Soft Matter, Langmuir, Colloids and Surfaces A, Biointerphases, Particle and Particle Systems Characterization, and Journal of Experimental Nanoscience.

28

Novel Electrocatalyst for Oxygen Reduction Reaction

- Theoretical and Experimental Investigations -

Kohei Uosaki,1,2,3 Ganesan Elumalai,1,3 Hung Cuong Dinh,2 Andrey Lyalin,1 Tetsuya Taketsugu,1,3 and Hidenori Noguchi1,2,3

1Ctr. for Green Res. Energy & Env. Mater. and Global Res. Ctr. for Env. & Energy Nanomat. Sci. (GREEN), Natl. Inst. Mater. Sci. (NIMS), Tsukuba 305-0044, Japan

2Int. Ctr. Mater. Nanoarchitectonics (WPI-MANA), NIMS3Grad. Sch. Chem. Sci. & Eng., Hokkaido Univ., Sapporo 060-0810, Japan.

E-mail: uosaki.kohei@nims.go.jp

Large overpotential for oxygen reduction reaction (ORR) is the origin of the major loss of the efficiency of hydrogen – oxygen fuel cell. Although Pt based materials work as efficient electrocatalysts, they have several problems such as high cost, less abundance, poor stability, and still sluggish kinetics and worldwide efforts have been devoted to develop novel electrocatalysts for ORR to solve these problems.

We have been working on novel electrocatalyst based on hexagonal boron nitride (h-BN). Although BN is an insulator with a wide band gap (5.8eV), theoretical studies showed that the band gap of h-BN monolayer can be used as an ORR catalyst [1-4] and experimental studies proved that Au electrodes modified with various types of h-BN indeed act as effective ORR electrocatalysts [4, 5]. Oxygen is, however, mainly reduced to H2O2 via 2-electron process, while it is reduced to H2O via 4-electron process at Pt electrode and the overpotential is still high compared with Pt electrode. Theoretical study suggests the origin of electrocatalytic activity of BNNS is the presence of BN - Au interactions through B-and/or N-edge structures. Thus, higher ORR activity can be expected by increasing BN - Au interactions.

Higher BN - Au interactions are achieved by depositing gold nanoparticles (AuNPs) on BNNS (Au-BNNS), which is then placed on a Au electrode (Au-BNNS/Au). Not only ORR starts at more positive potential but also the more than 50% of oxygen is reduced to H2O at Au-BNNS/Au, proving the high electrocatalytic activity of Au-BNNS/Au for ORR [6].

References

[1] A. Lyalin, A. Nakayama, K. Uosaki, and T. Taketsugu, PCCP, 2013, 15, 2809.[2] A. Lyalin, A. Nakayama, K. Uosaki, and T. Taketsugu, JPC C, 2013, 117, 21359.[3] A. Lyalin, A. Nakayama, K. Uosaki, and T. Taketsugu, Top. Cat., 2014, 57, 1032.[4] K. Uosaki et al., J. Amer. Chem. Soc., 2014, 136, 6542.[5] G. Elumalai, H. Noguchi, and K. Uosaki, PCCP, 2014, 16, 13755.[6] G. Elumalai et al., Electrochem. Comm., 2016, 66, 53 (2016).

29

Kohei UOSAKI, Dr., Prof.

Affiliation: Center for Green Research on Energy & Environmental Materials, Global Research center for Environment and Energy based on Materials Science (GREEN), and International Center for Materials Nanoarchitechtonics (MANA), National Institute for Materials Science (NIMS)

Address: 1-1 Namiki, Tsukuba, Ibaraki 305-0044, JapanTel: +81-29-860-4301; Fax: +81-29-851-3362E-mail: uosaki.kohei @nims.go.jp

Major Fields: Electrochemical Surface Science, Energy Conversion, and Non-linear Spec-troscopy

Biography: 1969 B. Eng. (Osaka University)1971 M. Eng. (Osaka University)1971-1978 Research Chemist (Mitsubishi Petrochemical Co. Ltd.)1974-1976 Graduate Student (Flinders University of South Australia; Ph. D. awarded

1977)1978-1980 Research Officer (Inorganic Chemistry Lab., Oxford University)1980-1981 Assistant Professor (Hokkaido University)1981-1990 Associate Professor (Hokkaido University) 1990-2010 Professor (Hokkaido University)2008- Principal Investigator (MANA, NIMS) 2010- Emeritus Professor and Adjunct Professor (NIMS)2013- Fellow and Director of GREEN (NIMS)2016- Director, Center for Green Research on Energy & Environmental Materials

(NIMS)

30

Adaptive Porous Materials for Device Fabrication

Cara DohertyCSIRO Manufacturing

Research Way, Clayton, 3168, AustraliaE-mail: Cara.Doherty@csiro.au

Advanced porous materials are integral for a variety of applications such as energy, gas separation and water purification. Incorporating these porous materials into devices for detection and sensing requires the ability to control the position of these materials through various fabrication techniques.[1-2] The additional control of the functionality within the porous frameworks enables us to fabricate multifunctional platforms (e.g. Lab-on-a-chip).

Here I will present some innovative approaches for the preparation of functional miniaturised devices.[3-5] I will discuss the ability to fabricate and finely tune the pore size of a variety of materials including metal-organic frameworks, thermally rearranged polymers and mesoporous materials hence allowing them to accurately target, filter or capture desired molecules. Combining bottom-up (self-assembly) with top-down (DXRL) technologies provides highly accessible functional surface areas, and controlled sites suitable for bio-molecular attachment.

One emerging and complimentary analytical technique to investigate the size and distribution of micropores in these materials is Positron Annihilation Lifetime Spectroscopy (PALS) which can precisely measure pore sizes and distributions under various conditions [6-7]. I will highlight how this technique can reveal important structure-property relationships so that the materials can be tailored for specific applications.

[1] Doherty, et al., Acc. Chem. Res., 2014, 47, 396

[2] Falcaro…, Doherty et al., Chem. Soc. Rev., 2014, 43, 5513

[4] Doherty, et al., Adv Mater., 2013, 25, 4701

[5] Doherty et al., J Chem. Mater, 2012, 22, 16191

[6] Han…, Doherty et al., Small, 2013, 9, 2277

[7] Petzetakis, Doherty, et al., Nat. Comm. 2015, 6, 7529

[8] Park..., Doherty, et al., Nature, 2016, 532, 480 Patterned MOF, Doherty et al, Adv. Mater., 2013,

25, 4701.

31

Dr. Cara Doherty

Affiliation: CSIRO Manufacturing

Address: Research Way, Clayton, 3168, AustraliaTel: +61 3 9545 2880E-mail: Cara.Doherty@csiro.au

Major Fields: Materials science, Porous Materials, Positron Annihilation Lifetime Spec-troscopy

Biography: 2002 Honors Degree Applied Physics (Curtin University of Technology)2002-2004 Research and Development Scientist, Structural Monitoring Systems Ltd.2005-2009 PhD Physical Chemistry (The University of Melbourne)2009-2014 Postdoctoral Researcher (CSIRO, Materials Science and Engineering)2014 L’Oréal Women in Science Fellow2014- Research Scientist (CSIRO, Manufacturing)

32

Water Permeation through Polymeric Membranes

Sandra KentishParticulate Fluids Processing Centre, Department of Chemical and Biomolecular

Engineering, The University of Melbourne, 3010 AustraliaE-mail: sandraek@unimelb.edu.au

Water is a unique molecule that can interact with polymeric membranes in a variety of ways. It can swell the polymer, reducing the glass transition temperature and increasing the diffusion coefficient. Conversely, it can form clusters, linear chains, or an entirely separate phase within the polymer. Such ‘pore filling’ behaviour leads to a decline in diffusion coefficient and can result in a deviation from the solution diffusion model usually used to describe transport through a membrane. Water also competes for sorption sites with other molecules, leading to reduced solubility of these species. This presentation will give an overview of the work that has been done within my group on this topic. The work encompasses the impact of water structure on reverse osmosis membranes as well as membranes for carbon capture and for recovery of water vapour.

33

Professor Sandra Kentish

Professor Sandra Kentish is Head of the Department of Chemical and Biomolecular Engi-neering and Associate Dean Industry within the Melbourne School of Engineering at The University of Melbourne. She is also an invited Professor at the Centre for Water, Earth and the Environment within the Institut National de la Recherche Scientifique (INRS) in Canada.

Professor Kentish has broad interests in industrial separations, particularly the use of membrane technology for energy, food and water applications. She has been the Disci-pline Leader in the CRC for Greenhouse Gas Technologies (CO2CRC) for Membrane Tech-nology since 2003. She has also been a member of the Research Advisory Committee for the National Centre of Excellence in Desalination since 2010. She was the Deputy Director of the Melbourne Energy Institute from 2009 - 2012. Before commencing an academic career, Professor Kentish spent nine years in industry, with positions in Exxon Mobil, Ko-dak Australasia and Kimberly Clark Australia.

34

Characterization and Surface Properties of Immobilized Polyelectrolyte Brushesin Aqueous Environment

Atsushi Takahara1Institute for Materials Chemistry and Engineering,

2 International Institute for Carbon-Neutral Energy Research (WPI-I2CNER), Kyushu University, Fukuoka 819-0395, Japan

E-mail: takahara@cstf.kyushu-u.ac.jp

Soft interfaces offer fascinating opportunities for addressing numerous problems of both academic and industrial interest: high-quality, functional or protective coatings, composite materials, surface engineered particles, metal-organic interfaces, biological applications, micro-patterning, colloids, nanoparticles, functional devices, etc. Polymers chemically grafted to the surface of substrates are typical soft interfaces known as polymer brushes. Surfaces formed from polyelectrolyte brushes, whose polymers composed of a polyelectrolyte, are particularly attractive because of their potential in applications including adhesion, antifouling, and water lubrication systems. In this presentation, our recent researches on control of wettability and adhesion through precise design of soft interfaces such as a polyelectrolyte brush surface are presented. We started from fundamental science including precise polyelectrolyte synthesis1) and solution characterization of polyelectrolytes2,3). On the basis of fundamental studies, we have successfully controlled 1) superhydrophilicity4) and antifouling properties5), 2) repeatable adhesion6,7), and 3) superlubricant behaviors by utilizing immobilized polymer brushes8,9).

References1. M. Kobayashi, M. Terada, Y. Terayama, M. Kikuchi, A. Takahara, Isr. J. Chem., 52, 364

(2012).2. M. Kobayashi, Y. Terayama, M. Kikuchi, A. Takahara, Soft Matter, 9, 5138 (2013).3. M. Kikuchi, Y. Terayama, T. Ishikawa, T. Hoshino, M.Kobayashi, N. Ohta, H. Jinnai, A.

Takahara, Macromolecules, 48, 7194 (2015).4. M. Kobayashi, Y. Terayama, H. Yamaguchi, M. Terada, D. Murakami, K. Ishihara, A.

Takahara, Langmuir, 28, 7212 (2012).5. Y. Higaki, J. Nishida, A.Takenaka, R. Yoshimatsu, M. Kobayashi, A. Takahara, Polym.

J., 47, 811 (2015).6. M. Kobayashi, M. Terada, A. Takahara, Soft Matter, 7, 5717 (2011).7. M. Kobayashi, A. Takahara, Polym. Chem., 4, 4987 (2013).8. M. Kobayashi, M. Terada, A. Takahara, Faraday Discus., 156, 403 (2012).9. M. Kobayashi, H. Tanaka, M. Minn, J. Sugimura, A. Takahara, ACS Appl. Mater.

Interfaces, 6, 20365 (2014).

35

Atsushi TAKAHARA, Dr., Prof.

Affiliation: Professor, Institute for Materials Chemistry and Engineering, International Institute for Carbon-Neutral Energy Research (WPI-I2CNER), Kyushu University

Address: 744 Motooka, Nishi-ku, Fukuoka 819-0395, JAPANTel: +81-92-802-2517; Fax: +81-92-802-2518E-mail: takahara@cstf.kyushu-u.ac.jp

Major Fields: Polymer Surface and Interfaces, Polymer Nanocomposites, Characteriza-tion of soft materials by quantum beam

Biography: 1980 Master Degree (Kyushu University)1983 Doctor Degree (Kyushu University)1983-1985 Assistant Professor (Faculty of Engineering, Kyushu University)1985-1999 Associate Professor (Faculty of Engineering, Kyushu University)1999-2003 Professor (Institute for Fundamental Research of Organic Chemistry,

Kyushu University)2003- Professor (Institute for Materials Chemistry and Engineering, Kyushu

University)2005-2008, 2011-2017 Member, Science Council of Japan2008-2014 Project Leader (JST/ERATO Takahara Soft-Interface Project) 2013-2017 Director (IMCE, Kyushu University)

36

Suspension Yielding is Not Stressful

Anthony D. SticklandParticulate Fluids Processing Centre

Department of Chemical and Biomolecular EngineeringThe University of Melbourne, Australia

E-mail: stad@unimelb.edu.au

At high enough solids concentrations, strongly-flocculated particulate suspensions behave as soft solids at low shear stresses or strains, and then yield and flow viscously at high shear stresses or strains. Understanding the nature of suspension yielding and flow is critical in many processing applications such as pipeline and open channel flow, mixing, slumping, and spreading. Typically such materials are described as ‘yield stress’ materials, a concept that is encapsulated in viscoplastic models such as the Herschel-Bulkley model, which use ‘yield stress’ as the yielding criterion.

However, extensive rheological testing shows suspension shear behaviour is much more complex and that viscoplastic models with a fixed yield stress do not sufficiently capture this behaviour. Instead, suspensions exhibit non-linear viscoelasticity prior to yielding, time-and rate-dependent yielding and non-monotonic steady-state flow. The non-linear viscoelasticity can be described with rate and particle size dependent strain-softening. At high concentrations, yielding occurs at strains ~1 due to ‘cage melting’ or steric hindrance. At lower concentrations, yielding occurs at lower strains due to bond breaking. The non-monotonic flow is attributed to strain rate-dependent softening of the network stress contribution, which vanishes at Péclet numbers ~1. Rate-dependent softening explains why some materials show a definite yield stress in some experiments but variable or erratic behaviour in others and why some suspensions shear band in stress or pressure controlled flows. These constitutive descriptions extend across a range of suspensions.

The conclusion form this work is that ‘yield strain’ or ‘yield strain energy’ are more appropriate criteria compared to ‘yield stress’.

37

Dr. Anthony D. STICKLAND

Affiliation: Particulate Fluids Processing Centre (PFPC), Department of Chemical and Biomolecular Engineering, The University of Melbourne

Address: Rm 3.24, Bldg 165, The University of Melbourne, Grattan St, Parkville, 3010, AustraliaTel: +61-8344-3430; Fax: +61-8344-4153E-mail: stad@unimelb.edu.au

Major Fields: Solid-liquid separation, suspension shear rheology, wastewater treatment

Biography: 2000 Bachelor of Engineering (Hons), Bachelor of Science (Hons) (The

University of Melbourne)2005 PhD (Chemical Engineering) (The University of Melbourne)2005-2006 Research Fellow (The University of Melbourne)2006-2008 Research Scientist (ICI / AkzoNobel, Wilton, UK)2008-2009 Project Leader (AkzoNobel, Melbourne, Australia)2009-2012 Research Fellow (The University of Melbourne)2012- Senior Lecturer (The University of Melbourne)

38

Construction of Regularly Assembled StructuresComposed of Liquid Crystalline Filamentous Viruses

Toshiki Sawada and Takeshi SerizawaDepartment of Chemical Science and Engineering,

School of Materials and Chemical Technology, Tokyo Institute of Technology2-12-1-H121 Ookayama, Meguro-ku, Tokyo 152-8550, Japan

E-mail: tsawada@polymer.titech.ac.jp

Regularly assembled structures in a controlled manner lead notable excel-lent properties with great potentials in many fields, including nanotechnol-ogy and material science. Especially, biomolecular-based assemblies exhibit better control due to their monodisper-sity, and are utilized in diverse material fields. Among various biomolecules, recent studies have demonstrated that filamentous M13 phages (Figure 1) act as components to construct bioinspired materials. Since surface modification of M13 phages has been established through genetic engineering and synthetic chemical methods, M13 phages are regarded as po-tential components of nanomaterials. Herein, we demonstrate hydrogels and solid films composed of regularly assembled M13 phages.

The genetically engineered M13 phages displaying tag peptides (antigens) and antibody-immobilized gold nanoparticles (GNPs) were utilized. The mixed solutions of the phages and the GNPs were self-assembled into hydrogels under certain conditions. Absorption spectra and transmission electron microscopy indicated that the regularly assembled network structures of several hundreds nanometers were constructed by the GNPs. On the other hand, polarized optical microscopy observation showed that the phages behaved as lyotropic liquid crystals. The results indicated that each component was self-assembled into certain regular structures. When the genetically engineered M13 phages displaying gold-binding peptides and the bare GNPs were used, similar regularly structures were observed. These results suggested that specific interactions between the phages and the GNPs at the phage termini induced certain assembled structures for hydrogels.

Furthermore, M13 phages were applied to components for construction of virus solid films. We prepared phage films with various assembled structures and their thermal diffusivity of the films was measured by temperature wave analysis. The oriented structures of the phages in the films were characterized by polarized optical microscopic and atomic force microscopic observations. It was revealed that thermal diffusivity of the liquid crystalline films with oriented structures prepared by the flow-induced method was higher values than that with the disordered structure. Furthermore, the thermal diffusivity values of the films with nematic- and smectic-liquid crystalline orientated phage structures were slightly different, suggesting phage oriented structures were essential for the thermal diffusivity. The results indicated that thermophysical property of phage films could be controlled by their assembly.

Figure 1. Schematic illustration of M13 phage

39

Toshiki Sawada, Ph.D., Assist. Prof.

Affiliation: Department of Chemical Science and Technology, School of Materials and Chemical Technology, Tokyo Institute of Technology

Address: 2-12-1-H121 Ookayama, Meguro-ku Tokyo 152-8550, JapanTel: +81-3-5734-3655; Fax: +81-3-5734-3655E-mail: tsawada@polymer.titech.ac.jp

Major Fields: Soft Material and Biopolymer

Biography: 2010 Ph.D. (Tokyo Institute of Technology)2010-2012 Assistant Professor (The University of Tokyo)2012- Assistant Professor (Tokyo Insititute of Technology)

40

Gas Separation by a Free-Standing and Nanometer-Thick Membrane

Shigenori FUJIKAWAWPI-I2CNER, Kyushu University

744 Motooka, Nishi-ku Fukuoka 819-0395, JapanE-mail: fujikawa.shigenori.137@m.kyushu-u.ac.jp

Biological lipid bilayer membrane is an ideal example for precise and efficient molecular separation. One of its characteristics is free-standing property with molecular thickness, and molecular scale phenomena become dominant in the direction of the membrane thickness. Thus, artificial membrane with a free standing properties and nanometer thickness would be a unique property different from conventional membrane. Based on this idea, we have developed functional free-standing nanomembranes with a centimeter-scale of lateral size (Fig.1).[1],[2] These membrane are manipulable macroscopically, event its thickness is a few tens nanometers.

Figure 1. Free-standing nanomembrane (a) and the cross sectional image on a porous support (b)

We have succeeded to prepare a free-standing and ultrathin membrane with precise molecular filtration ability by designing nanochannels structures across a membrane. Our next target is to separate further small molecules, including CO2 and gaseous molecules, because membrane separation of CO2 is one of promising CO2 capture technologies. In this scope, we have developed membranes composed of polymer and inorganic materials.In polymeric nanomembranes, we have investigated cross linkable materials, such as an epoxy resin, urea and melamine derivatives, for the preparation of nanomembrane. In all case, we have succeeded to prepare free-standing membrane with a few tens nanometer thick, and the gas permeance of each membrane was investigated. In inorganic membrane, we employed the composite materials composed of titanium alkoxide carboxylic derivatives, such as phthalic acid, to control the gas selectivity of the membrane. Based on a spin-coating process, titania composite membrane with the thickness of 100 nm or less was prepared on a PDMS support. Some composite membrane, show preferential CO2 permeation over nitrogen.

In membrane separation, the thickness plays an important role for the efficient separation. Further thinning to reach the thickness of a biological lipid membrane is our challenge to create ideal membrane separation based on molecular dynamics.

Reference[1] S. Fujikawa, E. Muto, and T. Kunitake, Langmuir, 25(19), 11563-11568 (2009)[2] S. Fujikawa, E. Muto, and T. Kunitake, Langmuir, 23(8), 4629-4633 (2007)

41

Shigenori FUJIKAWADr., Associate Professor, (Division Lead Principal Investigator)

Affiliation: World Premier International (WPI) Research Center, the International Institute for Carbon-Neutral Energy Research (I2CNER), Kyushu University

Address: 744 Motooka, Nishi-ku Fukuoka 819-0395, JapanTEL&FAX: +81-92-802-6872E-mail: fujikawa.shigenori.137@m.kyushu-u.ac.jp

Major Fields: Surface nanofabrication, Membrane Science, Surface Science, and Nano-materials

Biography: 1996 Master Degree (Kyushu University, Japan)1999 Doctor Degree (Kyushu University, Japan)1999-2000 Japan Society for the Promotion of Science (JSPS) Postdoctoral

Researcher (Yale University, USA)2000-2003 Special Postdoctoral Researcher (RIKEN, Japan)2004-2011 Deputy of Laboratory Head (RIKEN, Japan)2011- Associate Professor (Kyushu University, Japan)2013- Division Lead Principle Investigator (Kyushu University, Japan)2014- Visiting Associate Professor, Principle Investigator (Tokyo Institute of

Technology, Japan)2007- Partner and Board Member, NanoMembrane Technologies Inc. (Japan)

42

Solid-State Biosensing toward Intraoperative Diagnostics

Benjamin ThierryFuture Industries Institute, University of South Australia, Mawson Lakes Campus, SA

5095, AustraliaE-mail: benjamin.thierry@unisa.edu.au

A technology enabling the accurate detection of tumour markers in biopsied and resected tissues within the time-frame of surgery would significantly improve cancer patient care. For instance, the possibility to intraoperatively detect the presence of metastatic tumour cells in regional lymph nodes would guide the surgeon during intervention and spare a significant number of patients a subsequent repeat surgery (up to 40% for breast cancer). We have recently developed a state-of-the-art Silicon Nanowire Field Effect Transistor (SiNW FET) sensing platform able to detect a single tumour cell within an hour in a whole LN. This remarkable result demonstrates that Si FETs are prime candidates for the realization of such rapid molecular diagnostic technologies. In this presentation, we will discuss the requirements and challenge of such intraoperative diagnostic platform and present recent developments in our laboratory on the fabrication and operation of such devices.

Figure 1: (a) SEM of a SiNW arrays. (b) SiNW FETs responses in both AC and DC measurement vs. logarithmic ALCAM concentrations. (c) SiNW FET impedimetric detection of KRT-19 associated to the presence of CTCs (2.5 CTCs / mL as detected by imaging flow cytometry - insert) in the peripheral blood of a stage IV colorectal cancer patient.

43

Benjamin THIERRY, Dr., A/Prof.

Affiliation: Future Industries Institute, University of South Australia

Address: Mawson Lakes Campus, SA 5095, AustraliaTel: +61 8 8302 3689;E-mail: benjamin.thierry@unisa.edu.au

Major Fields: Diagnostic, molecular imaging, disease models

Biography: 1999 M.Sc.A in Biomedical Engineering (Ecole Polytechnique Montreal)2004 Ph.D. in Biomedical Engineering (McGill University)2008-2015 Principal Investigator (Ian Wark Research Institute, University of South Australia)2012- Associate Professor (Ian Wark Research Institute, University of South Australia)2014-2017 NHMRC CDF2 Fellow2015- Research Leader (Future Industries Institute, University of South Australia)

44

Characterization of Electrode-Electrolyte Interfaces

Using Electrochemical Surface Forces Apparatus

Motohiro Kasuya Institute of Multidisciplinary Research for Advanced Materials (IMRAM), Tohoku

University2-1-1 Katahira, Sendai 980-8577, Japan

E-mail: kasuya@tagen.tohoku.ac.jp

The adsorption of ions on electrodes determines the surface potential and charge density of the electrode, thus quantitative evaluation of the ion adsorption on an electrode is necessary and has been one of the central questions in electrochemistry. Surface forces measurements have been regarded as one of the promising tools for evaluating the surface potential and the surface charge density based on an analysis of the electric double layer forces. We developed a new electrochemical surface forces apparatus (EC-SFA, Fig.1),1) which can perform the measurement on forces between symmetrical electrode surfaces, using the twin-path SFA.2) Using this apparatus, we evaluated the surface potential, charge density and ion adsorption on the two electrodes, gold3) and ferrocene modified electrodes,4) which were well studied in the research field of electrochemistry.

[References]1) T. Kamijo, M. Kasuya, M. Mizukami, K. Kurihara, Chem. Lett. 2011, 40, 674. 2) Kawai H., Sakuma H., Mizukami M., Abe, T., Fukao, Y., Tajima, H., Kurihara, K. Rev. Sci. Instrum. 79, 043701 (2008).3) M. Kasuya, K. Kurihara, Langmuir. 2014, 30, 7093.4) M. Kasuya, T. Sogawa, T. Masuda, T. Kamijo, K. Uosaki, K. Kurihara, J. Phys. Chem. C, in print DOI: 10.1021/acs.jpcc.5b12683.

Figure 1. Schematic illustration of electro- chemical surface forces apparatus (EC-SFA).

45

Motohiro KASUYA, Dr.

Affiliation: Institute of Multidisciplinary Research for Advanced Materials (IMRAM), To-hoku University

Address: 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, JapanTel: +81-22-217-6152; Fax: +81-22-217-6152E-mail: kasuya@tagen.tohoku.ac.jp

Major Fields: Surface Science and Photochemistry

Biography: 2003 Master Degree (Tohoku University)2006 Doctor Degree (Tohoku University)2006-2008 Postdoctoral Researcher (National Institute of Advanced Industrial

Science and Technology (AIST))2008-2010 Postdoctoral Researcher (Tohoku University)2010- Assistant Professor (Tohoku University)

46

Nano-Scale Properties of Drops, Bubbles and Microcapsules in Emulsions, Foams and Encapsulated Systems

Raymond DagastineDepartment of Chemical and Biomolecular Engineering and

the Particulate Fluids Processing CentreE-mail: rrd@unimelb.edu.au

In complex fluids, soft or deformable components, such as drops, bubbles, or micro-capsules, respond to their surrounds in a far more complicated manner than rigid particle dispersions. This creates challenges in the processing and the characterization of these systems for a diverse set of applications ranging from the purification of minerals or pharmaceuticals using solvent extraction processes to the formulation of emulsions and foams in food and personal care products. Our research group has developed novel methods to characterize the underlying nanoscale interactions between the colloidal size deformable objects, drops and bubbles, and more recently micro-capsules, which are often critical in developing a stability or desired function in a formulated product.

Our approach has focused on studies that are fundamental in nature in parallel with studies on more applied systems, often with the hope of translating knowledge from the fundamental systems to more applied areas. Our experimental approach has employed innovative methods using Atomic Force Microscopy (AFM) to visualize the collisions between micro-drops or micro-bubbles on the nanoscale as well as the controlled compression of microcapsules. This is coupled with companion theoretical analyses to account for shape changes from interfacial deformation, surface chemistry, and fluid flow in these measurements to allow us to extract useful information about the interaction forces or micro- and nano-mechanical properties of these materials and how they relate to a particular function in a formulation or complex fluid. This talk will first briefly highlight some key fundamental findings on the interactions between drops and bubbles. Then results for more recent studies including using drop interactions to monitor the shape transitions in highly concentrated surfactants and some recent work on characterizing microcapsules as a function of temperature will be discussed.

47

Raymond DAGASTINE, Prof.

Affiliation: Department of Chemical and Biomolecular Engineering and the Particulate Fluids Processing Centre, the University of Melbourne, Australia

Address: Department of Chemical and Biomolecular Engineering, the University of Melbourne, Parkville, Victoria 3010 Australia Tel: +61-3-8344-4704; Fax: +61-3-8344-4153E-mail: rrd@unimelb.edu.au

Major Fields: Colloid and Interfacial Sceine, Surface Forces, Scanning Probe Micrscopy

Biography: 1997 Bachelor of Chemical Engineering w/Dist. (University of Delaware)2002 Doctoral Degree (Carnegie Mellon University)2002-2004 Senior Lecturer (University of Melbourne)2004-2010 Senior Lecturer (University of Melbourne)2009-2014 ARC Futrue Fellow (University of Melbourne)2011-2015 Senior Technology Fellow (Melbourne Centre for Nanofabrication)2010-2015 Assocaite Professor and Reader (University of Melbourne)2015-Present Professor (University of Melbourne)

48

Self-Assembly of Amyloid Fibrils in One, Two and Three Dimensions:From Fundamentals to Applications

Raffaele Mezzenga, ETH Zurich, raffaele.mezzenga@hest.ethz.ch

Protein fibrils are protein aggregates, which can be generated from food-grade proteins by unfolding and hydrolysis. The resulting protein fibrils can be used in a broad context of applications. In food applications, they may serve as texture enhancers, gelling agents, thickeners as well as surfaces and interfaces stabilizers. To fully exploit their potential, it is necessary to understand these systems at the most fundamental level. At length scales above the well-established atomistic fingerprint of amyloid fibrils, these colloidal aggregates exhibit mesoscopic properties comparable to those of natural polyelectrolytes, yet with persistence lengths several orders of magnitude beyond the Debye length. This intrinsic rigidity, together with their chiral, polar and charged nature, provides these systems with some unique physical behavior in one, two and three dimensions. In this talk I will discuss our current understanding on the mesoscopic properties of amyloid fibrils at the single molecule level, the implication of their semiflexible nature on their liquid crystalline properties, and I will illustrate how this information prove useful in understanding their collective behavior in bulk and when adsorbed at liquid interfaces. By the careful exploitation of the physical properties of amyloid fibrils, the design of advanced materials with unprecedented physical properties become possible, and I will give a few examples on how these systems can ideally suit the design not only of complex food systems, but also of biosensors and biomaterials, catalytic and water purification membranes.

An example of functional amyloid membranes for universal water purification. (A) Structure of the β-lactoglobulin protein with highlighted the strongest heavy metal binding motif, the 121-cys with a lead ion attached. (B) Amyloid-forming fragment (LACQCL) from β-lactoglobulin with docked lead acetate metal ions. (C) Schematic representation of heavy metal ion purification by amyloid-carbon adsorbers. (D) Scanning electron microscope (SEM) image of the composite membrane and (E) Higher magnification SEM image.From Bolisetty & Mezzenga, Nature Nanotechnology 2016.

49

Prof. Dr. Raffaele Mezzenga, ETH Zurich

Raffaele Mezzenga received his master degree (Summa Cum Laude) from University of Perugia, Italy, in Materials Science and Engineering, while actively working for the European Center for Nuclear Research (CERN), Geneva, and NASA, Houston, in problems related to the interaction between elementary particles and polymer-based structures (NASA Space Shuttle Discovery mission STS91). In 2001, he obtained a PhD in the field of Polymer Physics (with honors), from the Swiss Federal Institute of Technology, Lausanne (EPFL), focusing on the thermodynamics of thermoset-hyperbranched polymer reactive blends. He then spent 2001-2002 as a postdoctoral scientist at University of California, Santa Barbara, working on self-assembly of polymer colloids for the design of new semiconductive organic materials. In 2003 he joined the Nestlé Research Center, in Lausanne as a research scientist, working on self-assembly of surfactants, natural amphiphiles and lyotropic liquid crystals. In 2005 he was hired as an Associate Professor in the Physics Department of the University of Fribourg, where he has been a board and founding member of the Fribourg Center for Nanomaterials (Frimat). He was appointed Full Professor at ETH Zurich in September 2009, starting the new Food and Soft Materials group. He also is an Affiliated Professor of the Materials Department since 2010. His research focuses on the fundamental understanding of self-assembly processes in liquid crystalline polymers, supramolecular polymers, lyotropic liquid crystals, food and biological colloidal systems. Prof. Mezzenga has been a visiting Professor at Helsinki University of Technology (now Aalto University) and a Nestlé Distinguished Scientist. He is a board member of the Polymer and Colloid Division of the Swiss Chemical Society, and winner of the 2004 Swiss National Science Foundation Professorship Award. The value of his contribution has been recognized internationally by several reputed awards, among which the 2011 AOCS Young Scientist Research Award “For his pioneering work on polymers, colloids and liquid crystals”; the 2013 John H. Dillon Medal (American Physical Society), “For exceptional contributions to the understanding of self-assembly principles and their use to design and control materials with targeted functionalities” and the 2013 Biomacromolecules/Macromolecules Young Investigator Award (American Chemical Society) “in recognition of his outstanding contributions to the fundamental understanding of self-assembly processes in polymers and biological colloidal systems”.

50

Porous Materials for Energy and Environmental Applications

Rachel CarusoSchool of Chemistry, The University of Melbourne.

Melbourne, Victoria 3010, AustraliaE-mail: rcaruso@unimelb.edu.au

The structural properties of a material have a significant influence on how well the material can perform when used in an application. Hence developing synthesis routes that allow control over the structural properties can be paramount to improving the effectiveness of the material. In this talk the preparation and characteristics of materials for perovskite based photovoltaics and water purification will be the focus.

The working component of perovskite solar cells has a thickness less than one micrometer. Therefore, the morphology and interfacial properties of the individual layers within the cell are very important. We have focused our research on the perovskite material and the electron transport layer, for which titanium dioxide is frequently used. The perovskite crystallization can be influenced by gas flow, and the solvents and vapour present during the deposition process. Variation of the titania nanostructure has been achieved through solvothermal processes and the effect of the nanostructure on the cell efficiency determined. I will give a brief introduction to perovskite solar cells and our work in this area.

Another major challenge that requires addressing is the ability to obtain a sufficient supply of clean water for a growing population. Hence significant effort is going into researching materials that can remove pollutants from water. This can be achieved through adsorption of the pollutant onto a support that can be separated from the water, or destruction of the contaminant through degradation processes. The effectiveness of the material to adsorb or degrade pollutants is dependent on the materials properties. Careful manipulation of the synthesis process of materials allows control over such characteristics - the crystal size and phase, pore size and structure, outer morphology and surface functionality. Examples of the synthesis and characterization of materials with application in the removal of pollutants from water will be given.

51

Rachel CARUSO, Assoc. Prof.

Affiliation: School of Chemistry, The University of Melbourne and CSIRO Manufacturing

Address: School of Chemistry, The University of Melbourne, Melbourne, Victoria 3010, AustraliaTel: +61-3-8344-7146E-mail: rcaruso@unimelb.edu.au

Major Fields: Porous materials, Photocatalysis, Photovoltaics

Biography: 1998 PhD(Science) (The University of Melbourne)1998-2002 Postdoctoral Fellow – Group Leader (Max Planck Institute of Colloids and Interfaces)2002-2008 ARC Australian Research Fellowship (The University of Melbourne)2008 - OCE Science Leader (CSIRO)2008-2010 Senior Lecturer (The University of Melbourne)2010-2014 ARC Future Fellow (The University of Melbourne/CSIRO)2011- Associate Professor and Reader (The University of Melbourne)

52

Robust Sealing Strength of Hydrophobically-modified, Alaska Pollock-derived Gelatin-based Biodegradable Sealant Under Wet

Condition

Tetsushi TaguchiBiomaterials Field, Research Centre for Functional Materials, Natl. Inst.

Mater. Sci.1-1 Namiki, Tsukuba 305-0044, Japan E-mail: TAGUCHI.Tetsushi@nims.go.jp

Tissue adhesive is a biomedical material that can bond tissues together after surgical operations. There are mainly three types of tissue adhesives used in clinical fields, however, these adhesives still have disadvantages on biocompatibility and bonding strength. Therefore, a novel surgical adhesive was developed by partially modifying the amino groups of a Alaska pollock-derived gelatin derivative with hydrophobic groups, such as cholesteryl groups (Chol-ApGltn), which was combined with the crosslinker, pentaerythritol poly(ethylene glycol) ether tetrasuccinimidyl glutarate (4S-PEG). The burst strength of the resultant adhesive was tested using fresh porcine aorta as an adherend. Burst strength increased with increasing degree of Chol modification up to a maximum value of 8.3 mol% (8.3Chol-ApGltn). The highest burst strength of the 8.3Chol-ApGltn/4S-PEG adhesive was 341.3 ± 77.5 mmHg, which was 4- and 12-fold higher than that of the original ApGltn/4S-PEG and commercial fibrin adhesives, respectively. The 8.3Chol-ApGltn/4S-PEG adhesive swelled only slightly in saline (1.1-fold as compared to commercially prepared adhesive). Furthermore, tissue migration into the 8.3Chol-ApGltn/4S-PEG adhesive and subsequent biodegradation was observed following implantation in mice subcutaneous tissue for 4-8 weeks. These results suggest that the 8.3Chol-ApGltn/4S-PEG adhesive has potential for biomedical applications in the field of cardiovascular and thoracic surgery.

53

Tetsushi TAGUCHI, Dr., Group Leader

Affiliation: Polymeric Biomaterials Group, Biomaterials Field, Research Center for Functional Materials, National Institute for Materials Science (NIMS)

Address: 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan Tel: +81-29-860-44498; Fax: +81-29-860-4752E-mail: TAGUCHI.Tetsushi@nims.go.jp

Major Fields: Biomaterials, Biointerface, Adhesive Materials, and Tissue Engineering

Biography:1999-2000 Postdoctoral Fellow (National Institute for Advanced Interdisciplinary

Research) 2000-2002 CREST Researcher (National Institute for Research in Inorganic Materials)2002-2006 Researcher of Biomaterials Center, NIMS2006-2011 Senior Researcher of Biomaterials Center, NIMS 2007- Associate Professor (University of Tsukuba) 2011-2016 MANA Researcher, MANA, NIMS2015- Director of Bioadhesive Materials Technology Center, NIMS 2016- Group Leader of Polymeric Biomaterials Group, NIMS

54

Engineering Nanostructure in Ionic Liquids and Deep Eutectic Solvents

Gregory G. WarrSchool of Chemistry, The University of Sydney

NSW 2006, AustraliaE-mail: gregory.warr@sydney.edu.au

Over the past two decades, ionic liquids have emerged as a versatile class of novel solvents for applications ranging from bioprocessing, synthesis, and catalysis to electrochemistry to colloid, surface and polymer science. Their reputation as environmentally-friendly liquids arises primarily from their negligible vapour pressures, and overlooks their high economic and energetic synthetic cost as well as their various chemical downsides, such as high fluorine content.The structure of ionic liquids differs in important ways from the simple picture of a molten salt: The critical role of amphiphilic nanostructure in the performance and properties of ionic liquids across many applications has only recently been recognized. Currently, new generations of ionic liquid-like solvents, including deep eutectic solvents and complex or solvate ionic liquids, are under development. These promise to deliver comparable or better performance, but will also live up to their potential as greener and cheaper liquids and solvents. The major challenge in their development, and the major impediment to their wider uptake, is that these new liquids lack the amphiphilic nanostructure essential to the performance of traditional ionic liquids as solvents, working fluids, and continuous phases.

Neutron and X-ray scattering and diffraction techniques yield detailed and exquisite insights into ionic liquid structure. These have been used to reveal how the ionic liquids arrange themselves into amphiphilic nanostructures, but also how they accommodate various solutes, revealing why they are such remarkable solvents. This also suggests strategies for engineering nanostructure in the next generation of green liquids and solvents. Figure 1. Simulation box from the fit to neutron

diffraction data for pyrrolidinium acetate. Polar moieties are light grey and apolar light grey.

1 “Structure and Nanostructure in Ionic Liquids” R. Hayes, G.G. Warr, R. Atkin, Chem. Rev. 2015, 115, 6357–6426 (10.1021/cr500411q)

55

Gregory WARR, Prof.

Affiliation: School of Chemistry, The University of Sydney

Address: School of Chemistry F11, The University of Sydney, NSW 2006, AustraliaTel: +61-2-9351-2106E-mail: gregory.warr@sydney.edu.au

Major Fields: Self-Assembly, Ionic Liquids, and Soft Nanomaterials

Biography: 1982 BSc (Hons) (The University of Melbourne)1986 PhD (The University of Melbourne)1986-1987 Postdoctoral Fellow (University of Minnesota)1987-1988 Research Associate (CEN de Saclay)1988-1992 Lecturer (The University of Sydney)1992 Visiting Scientist (Princeton University)1993-1996 Senior Lecturer (The University of Sydney) 1996-1997 Visiting Scientist (Princeton University) and Principal Scientist (Rhodia/CNRS Complex Fluids Laboratory)1998-2003 Associate Professor (The University of Sydney)2001 Visiting Professor (Centre de Recherche Paul Pascale/University of Bor-

deaux) 2004- Professor of Physical Chemistry (The University of Sydney) 2004 Guest Researcher (NIST Center for Neutron Research) 2007-2013 Head, School of Chemistry (The University of Sydney)

56

Functional Peptides and Soft Complex Materials

Sally Gras

Department of Chemical & Biomolecular EngineeringThe University of Melbourne, Parkville, VIC 3010

The Bio21 Institute, 30 Flemington Road, Parkville, VIC 3010E-mail: sgras@unimelb.edu.au

We are interested in the design, synthesis and application of short hydrophobic peptides for use as materials. Many of the systems we study self-assemble to form β-sheet rich fibers known as amyloid fibrils. These include naturally occurring bacterial peptides that assist bacterial growth and de novo designed synthetic peptides that we are exploring as potential new materials. Such peptide materials have been nucleated using synthetic DNA molecules, known as DNA origami, to create larger self-organizing structures. The interactions between fibril materials and mammalian cells have also been characterized. Other materials are designed with anti-inflammatory functions including the release of short functional peptides to promote the healing of human tissues.

A second area of interest is soft food materials, such as dairy products. We are interested in improving our understanding of the assembly, structure and function of these complex materials. The ability to predict and tailor textures or reverse engineer desirable properties is of interest to food manufacturers including the Australian dairy industry.

57

Associate Professor Sally Gras

Affiliation: ARC Dairy Innovation Hub, The University of Melbourne; Department of Chemical & Biomolecular Engineering, The University of Melbourne; Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne.

Address: Dept. Chemical & Biomolecular EngineeringThe University of Melbourne VIC 3010Tel: +61 3 8344 6281; E-mail: sgras@unimelb.edu.au

Major Fields: Peptide assembly, Surface Science, Nanomaterials, Amyloid fibrils, microscopy, food microstructure

Biography:2002 BEng (Chemical) with First Class Honours, The University of Melbourne

(UoM)2002 BSc (Biochemistry and Molecular Biology) with First Class Honours, UoM 2003-2006 Gates Research Scholar, Cambridge, sponsored by the Bill and Melinda

Gates Foundation.2006 PhD, Cambridge University, United Kingdom2006- Research Group Leader, Bio21 Molecular Science and Biotechnology

Institute, UoM2006-2009 Lecturer, Department of Chemical and Biomolecular Engineering, UoM2009-2014 Senior Lecturer, Department of Chemical and Biomolecular Engineering,

UoM2014- Associate Professor and Reader, Department of Chemical and

Biomolecular Engineering, UoM2014- Director, The ARC Dairy Innovation Hub2015- Associate Director Bio21 Molecular Science and Biotechnology Institute,

Molecular Systems Theme

58

Nanostructure Formation at Polymer-Surfactant Interfaces – Opportunities for New Stimuli Responsive Delivery Systems

Kristian Tangso and Ben J BoydMonash Institute of Pharmaceutical Sciences

381 Royal Pde, Parkville, VIC, 3052E-mail: ben.boyd@monash.edu

Unlike the chaotic coacervated material formed on interaction of oppositely-charged polymers in eg. layer by layer assembly, the interface between oppositely-charged surfactant and polymer solutions can generate rich self-assembled structures, not necessarily found in the binary surfactant-water phase diagram. We have been using spatially-resolved scattering approaches to understand the structures formed at these interfaces. Specifically by contacting the solutions in a flat capillary cell to form a well-defined interface, SAXS can been used in a ‘scanning’ mode, to determine the changes in self-assembled structure with 100 micron resolution through the interface. The structure can then be manipulated through changes in variables such as temperature or pH to yield stimuli responsive materials that can be used to form eg. nanostructured capsules for controlled release applications. Capsules have also been formed from the materials containing a dye by introducing droplets of one liquid into the other, and monitoring the inherent and stimulated release of the dye from the capsules. As one example, the bile-salt + chitosan system formed a lamellar structure at the interface (figure below) [1]. Increasing the temperature of the system above physiological temperature led to destruction of the lamellar phase and stimulated release of the encapsulated dye. These systems indicate the potential for new stimuli-responsive materials that have been enabled by the spatially-resolved scattering capabilities at the Australian Synchrotron.

[1] Tangso, Kristian; Lindberg, Seth; Hartley, Patrick; Knott, Robert; Spicer, Patrick; Boyd, Ben ACS Applied Materials & Interfaces accepted 21/7/14

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Ben J. Boyd, Prof.

Professor Ben Boyd has a PhD from the University of Melbourne and after industry ex-perience in the explosives and pharmaceutical industries, he commenced an academic position at Monash University, Melbourne, Australia. His group is focussed on colloidal and structural aspects of lipids, lipid self-assembly and pharmaceutical systems, focused on controlling materials at the colloidal scale for delivery in pharma and other fields. His group also has fun inventing new synchrotron techniques for studying these sys-tems. He is currently Secretary of the Controlled Release Society and is an active mem-ber of the Australian Colloid and Interface Society. He serves on the editorial boards of several journals including Journal of Colloid and Interface Science, Associate Editor for Drug Delivery and Translational Research and Journal of Pharmaceutical Sciences. He was the recipient of the Gattefossé-sponsored AAPS 2011 Lipid-based Drug Delivery Award Outstanding Research Award, and is currently on an Australian Research Coun-cil-funded Future Fellowship for the discovery and development of light activated drug delivery systems. His group’s website is at nonlamellar.com

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