Adrenergic Receptor · Atenolol is a selective β1 receptor antagonist. Target: Adrenergic Receptor...
Transcript of Adrenergic Receptor · Atenolol is a selective β1 receptor antagonist. Target: Adrenergic Receptor...
Adrenergic ReceptorBeta Receptor
Adrenergic receptors are a class of G protein-coupled receptors that are targets of the catecholamines especially norepinephrineand epinephrine Many cells possess these receptors and the binding of a catecholamine to the receptor will generally stimulatethe sympathetic nervous system The sympathetic nervous system is responsible for the fight-or-flight response which includeswidening the pupils of the eye mobilizing energy and diverting blood flow from non-essential organs to skeletal muscle There aretwo main groups of adrenergic receptors α and β with several subtypes α receptors have the subtypes α1 and α2 β receptorshave the subtypes β1 β2 and β3 All three are linked to Gs proteins which in turn are linked to adenylate cyclase Agonist bindingthus causes a rise in the intracellular concentration of the second messenger cAMP Downstream effectors of cAMP includecAMP-dependent protein kinase (PKA) which mediates some of the intracellular events following hormone binding
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Adrenergic Receptor Agonists Antagonists Inhibitors Activators amp Modulators
(+)-Penbutolol ((R)-Penbutolol (+)-Isopenbutolol) Cat No HY-116790A
(+)-Penbutolol is a β-adrenoceptor antagonistwith an IC of 074 μM (+)-Penbutolol is an50
optical isomer of l-penbutolol with Na+
channel-blocking action
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
(4E)-SUN9221Cat No HY-U00367
(4E)-SUN9221 is a potent antagonist of and withα1-adrenergic receptor 5-HT2 receptor
antihypertensive and anti-platelet aggregationactivities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
(R)-(+)-AtenololCat No HY-B2111
(R)-(+)-Atenolol is the less active enantiomer ofthe (RS)-atenolol (RS)-atenolol is aβ-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg
(R)-Carvedilol ((R)-BM 14190) Cat No HY-B0006C
(R)-Carvedilol ((R)-BM 14190) the R-enantiomer ofCarvedilol is a non-selective blockerβα-1(R)-Carvedilol exerts protection against thevascular or cardiac toxicity of Doxorubicin (DOX)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
(R)-TerazosinCat No HY-B0371B
(R)-Terazosin is an active R-enantiomer ofTerazosin (R)-Terazosin is a potent
antagonist with values of 651α1-adrenoceptor Ki
nM 101 nM and 197 nM for andα1a α1b respectivelyα1d-adrenoceptor
Purity 9977Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
(Rac)-Rotigotine hydrochlorideCat No HY-15394
(Rac)-Rotigotine hydrochloride is a racemate ofRotigotine
Purity 9776Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
(RS)-ButyryltimololCat No HY-102032A
(RS)-Butyryltimolol is the racemate ofButyryltimolol Butyryltimolol an effectiveprodrug of Timolol improves the cornealpenetration of Timolol Butyryltimolol is aβ-adrenergic blocker
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
(S)-Carvedilol ((S)-BM 14190) Cat No HY-B0006B
(S)-Carvedilol the S-enantiomer of Carvedilol isa non-selective blocker (S)-Carvedilolβα-1exerts protection against the vascular or cardiactoxicity of Doxorubicin (DOX)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
(S)-TerazosinCat No HY-B0371D
(S)-Terazosin is an active S-enantiomer ofTerazosin (S)-Terazosin is a potent andhigh-affinity antagonist with α-adrenoceptor Ki
values of 391 nM 079 nM and 116 nM for α1a and respectivelyα1b α1d-adrenoceptor
Purity 9977Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
(S)-Timolol Maleate (L-714465 Maleate MK 950) Cat No HY-17380
(S)-Timolol Maleate (L-714465 Maleate) is anon-cardioselective hydrophilic β-adrenoceptorblocker (S)-Timolol Maleate is widely used asstandard medication for intraocular pressure(glaucoma) by preventing the production of aqueoushumor
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg
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(plusmn)-BefunololCat No HY-101752
(plusmn)-Befunolol is a blocking agentβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
(plusmn)-Bisoprolol hemifumarate (Bisoprolol hemifumarate salt) Cat No HY-B0076
(plusmn)-Bisoprolol (hemifumarate) is a selective typeβ1 adrenergic receptor blocker Target AdrenergicReceptor Approved July 31 1992 Bisoprolol onbeta 1-adrenoceptor peptide induced autoimmunemyocardial damage
Purity 9965Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
25-DideoxyadenosineCat No HY-135878
25-Dideoxyadenosine is a potent andnon-competitive inhibitor viaadenylyl cyclasebinding the P-site with an of 3 microM IC50
25-Dideoxyadenosine is a nucleoside analog andexerts a potent action in heartantiadrenergic
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg 100 mg 250 mg
4-Hydroxypropranolol D7 hydrochloride ((plusmn)-4-hydroxy Propranolol D7 hydrochloride) Cat No HY-100634S
4-Hydroxypropranolol D7 hydrochloride((plusmn)-4-hydroxy Propranolol D7 hydrochloride) is adeuterium labeled 4-Hydroxypropranololhydrochloride
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
4-Hydroxypropranolol hydrochloride ((plusmn)-4-hydroxy Propranolol hydrochloride) Cat No HY-100634
4-Hydroxypropranolol hydrochlorid is an activemetabolite of Propranolol 4-Hydroxypropranololhydrochlorid is of comparable potency toPropranolol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
5-HT2 antagonist 1Cat No HY-U00365
5-HT2 antagonist 1 is a potent antagonist of with weak 5-HT2 receptor α1 adrenoceptor
blocking activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
AaptamineCat No HY-N4225
Aaptamine a spongean alkaloid isolated from a seasponge Aaptos aaptos is a competitive antagonistof and activates the p21 promoterα-adrenoceptorin a p53-independent manner
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Acebutolol D7Cat No HY-17497S
Acebutolol D7 is a deuterium labeled AcebutololAcebutolol is a selective β1 adrenergic receptorantagonist used in the treatment of hypertensionangina pectoris and cardiac arrhythmias
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Acebutolol hydrochlorideCat No HY-17497A
Acebutolol hydrochloride is a β1 adrenergic antagonist Acebutololreceptor (β1AR)
hydrochloride is used in the treatment ofhypertension angina pectoris and cardiacarrhythmias
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 5 g 10 g
ACTH (1-14) (Adrenocorticotropic Hormone Fragment 1-14) Cat No HY-P1582
ACTH (1-14) is a fragment of adrenocorticotrophinwhich regulates cortisol and androgen production
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ACTH (1-14) (TFA) (Adrenocorticotropic Hormone Fragment 1-14 TFA) Cat No HY-P1582A
ACTH (1-14) (TFA) is a fragment ofadrenocorticotrophin which regulates cortisol andandrogen production
Purity 9855Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg
ADRA1D receptor agonist 1Cat No HY-135270
ADRA1D receptor agonist 1 (compound (R)-9S) is apotent selective and orally active α1D
antagonist with a of 16 nMadrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
AGN 192836Cat No HY-100300
AGN 192836 is a potent and selective α2 adrenergicagonist with s of 87 41 and 66 nM forEC50
α2A α2B and α2C receptor respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ajmalicine (Raubasine) Cat No HY-N1919
Ajmalicine (Raubasine) is found in herbs ofCatharanthus roseus is an antihypertensive drugused in the treatment of high blood pressuredecreases peripheral resistance and bloodpressure
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Alfuzosin (SL 77499) Cat No HY-B0192
Alfuzosin is an α1 adrenergic receptor antagonistused to treat benign prostatic hyperplasia (BPH)
Purity 9981Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Alfuzosin hydrochloride (SL 77499-10) Cat No HY-B0192A
Alfuzosin hydrochloride is an α1 adrenergicreceptor antagonist used to treat benign prostatichyperplasia (BPH)
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Amezinium methylsulfate (Amezinium metilsulfate Lu-1631) Cat No HY-A0275
Amezinium metilsulfate has multiple mechanismsincluding stimulation of alpha and beta-1receptors and inhibition ofnoradrenaline andtyramine uptake
Purity 9951Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
Amibegron hydrochloride (SR 58611A) Cat No HY-103207
Amibegron hydrochloride is a selective agonist with an of 35 nMβ3-adrenoceptor EC50
for in rat colon Amibegronβ-adrenoceptorhydrochloride has anxiolytic and antidepressantactivity
Purity gt990Clinical Data No Development ReportedSize 5 mg
Amitraz (BTS-27419) Cat No HY-B1111
Amitraz is a non-systemic acaricide andinsecticide with alpha-adrenergic agonistactivity interaction with octopamine receptors ofthe central nervous system and inhibition ofmonoamine oxidases and prostaglandin synthesis
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
AncarololCat No HY-100141
Ancarolol is a blocking agentbeta-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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AR-08Cat No HY-U00371
AR-08 is an agonist of α2-adrenergic receptorused for the treatment of attention deficithyperactivety disorder (ADHD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ArbutamineCat No HY-16056
Arbutamine is a short-acting synthetic potentnonselective agonist thatβ-adrenoceptorincreases heart rate cardiac contractility andsystolic blood pressure Arbutamine is acatecholamine for a pharmacological cardiac stressagen
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
ArotinololCat No HY-122537A
Arotinolol is a nonselective αβ-adrenergic blocker and a vasodilating β-blockerreceptor
Arotinolol also shows potency for inhibiting thebinding of the radioligand I-ICYP to125
-serotonergic receptor sites5HT1B
Purity 9818Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Asenapine (Org 5222) Cat No HY-10121
Asenapine(Org 5222) inhibits adrenergic receptor(α1 α2A α2B α2C) with Ki of 025-12 nM andalso inhibits 5-HT receptor (1A 1B 2A 2B 2C5A 6 7) with Ki of 003-40 nM
Purity 9881Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Atenolol ((RS)-Atenolol) Cat No HY-17498
Atenolol is a selective β1 receptor antagonistTarget Adrenergic Receptor Atenolol is acardioselective beta-adrenergic blocker possessingproperties and potency similar to propranolol butwithout a negative inotropic effect [1 2]
Purity 9961Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Atipamezole (MPV 1248) Cat No HY-12380A
Atipamezole is a synthetic α -adrenoceptor2
with a of 16 nMantagonist Ki
Purity 9948Clinical Data Phase 1Size 10 mM times 1 mL 10 mg 50 mg
Atipamezole hydrochloride (MPV-1248 hydrochloride) Cat No HY-12380
Atipamezole hydrochloride is a synthetic with a of 16 nMα -adrenoceptor antagonist2 Ki
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Bambuterol ((plusmn)-Bambuterol KWD-2183) Cat No HY-17501
Bambuterol ((plusmn)-Bambuterol KWD-2183) is a longacting beta-adrenoceptor agonist (LABA) used inthe treatment of asthma it also is a prodrug ofterbutaline
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Bambuterol hydrochloride ((plusmn)-Bambuterol hydrochloride KWD-2183 hydrochloride) Cat No HY-17501A
Bambuterol hydrochloride ((plusmn)-Bambuterolhydrochloride KWD-2183 hydrochloride) is a longacting beta-adrenoceptor agonist (LABA) used inthe treatment of asthma it also is a prodrug ofterbutaline
Purity 9957Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Batefenterol (GSK961081 TD-5959) Cat No HY-12980
Batefenterol (GSK961081TD-5959) is a novel receptor antagonist andmuscarinic
agonist displays high affinityβ -adrenoceptor2
for hM2 hM3 muscarinic and hβ -adrenoceptor with2
values of 14 13 and 37 nM respectivelyKi
Purity 9817Clinical Data Phase 2Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
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Benzquinamide (P2647 BZQ Benzoquinamide) Cat No HY-U00244
Benzquinamide (P2647) is an antiemetic which canbind to the and α2A α2B α2C adrenergic
(α2-AR) with K values of 1365 691receptors i
and 545 nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BetaxololCat No HY-B0381
Betaxolol is a selective beta1 adrenergic receptorblocker used in the treatment of hypertension andglaucoma Target Beta1 Adrenergic ReceptorBetaxolol is a cardioselective beta-adrenergicreceptor blocking agent Betaxolol (5 mgkg viaip
Purity 9695Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Betaxolol hydrochloride (SL75212) Cat No HY-B0381A
Betaxolol Hydrochloride is a selective beta1adrenergic receptor blocker used in the treatmentof hypertension and glaucoma Target Beta1Adrenergic Receptor Betaxolol hydrochloride is acardioselective beta-adrenergic receptor blockingagent
Purity 9894Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Bevantolol hydrochlorideCat No HY-121186
Bevantolol hydrochloride is a selective andβ1α1-adrenergic receptor antagonist with valuespKi
of 783 69 in rat cerebral cortex respectivelyBevantolol hydrochloride is a potent Ca2+
antagonist
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 25 mg 50 mg 100 mg
BI-167107Cat No HY-121251
BI-167107 is a high affinity full agonist thatbinds to the β2 adrenergic receptor ( ) with aβ2ARdissociation constant of 84 pMKd
Purity 9981Clinical DataSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Bometolol HydrochlorideCat No HY-U00386
Bometolol Hydrochloride is a beta-adrenergicblocking agent used for the research ofcardiovascular disease
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brimonidine (UK 14304 AGN190342) Cat No HY-B0659
Brimonidine (UK 14304) is a full α2-adrenergicreceptor (α2-AR) agonist
Purity 9965Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Brimonidine tartrate (UK 14304 tartrate AGN190342 tartrate) Cat No HY-B0659A
Brimonidine tartrate (UK 14304 tartrate) is a fullα2-adrenergic receptor (α2-AR) agonist
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
BRL 37344 sodium (BRL 37344A) Cat No HY-101325
BRL 37344 sodium (BRL 37344A) is a specific agonist BRL 37344 sodiumβ3-adrenergic receptor
treatment significantly lowers the body weight ofobese mice
Purity gt990Clinical Data No Development ReportedSize 1 mg
Brombuterol D9 (Bromobuterol D9) Cat No HY-131104S
Brombuterol D9 (Bromobuterol D9) is a deuteriumlabeled Brombuterol Brombuterol is a β-adrenergic
agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Brombuterol D9 hydrochloride (Bromobuterol D9 hydrochloride) Cat No HY-131104AS
Brombuterol D9 hydrochloride (Bromobuterol D9hydrochloride) is a deuterium labeled Brombuterolhydrochloride Brombuterol hydrochloride is a
agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brombuterol hydrochloride (Bromobuterol hydrochloride) Cat No HY-131145
Brombuterol hydrochloride (Bromobuterolhydrochloride) is a agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BucindololCat No HY-103214
Bucindolol is a blockerβ1-adrenergic receptorwith intrinsic sympathomimetic activity used inthe research of heart failure
Purity gt990Clinical Data No Development ReportedSize 1 mg 5 mg
Carbazochrome sodium sulfonate (AC-17) Cat No HY-B0491A
Carbazochrome (sodium sulfonate) (AC-17) is anantihemorrhagic agent
Purity 9951Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carteolol hydrochloride (OPC-1085 hydrochloride) Cat No HY-17495A
Carteolol hydrochloride (OPC-1085 hydrochloride)is a non-selective beta blocker used to treatglaucoma
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carvedilol (BM 14190) Cat No HY-B0006
Carvedilol (BM 14190) is a non-selective βα-1blocker Carvedilol inhibits lipid peroxidation ina dose-dependent manner with an IC of 5 μM50
Carvedilol is a multiple action antihypertensiveagent with potential use in angina and congestiveheart failure
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) Cat No HY-B0006A
Carvedilol phosphate hemihydrate (BM 14190phosphate hemihydrate) is a non-selective βα-1blocker Carvedilol phosphate hemihydrate inhibits
with an IC of 5 μMlipid peroxidation 50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Centanafadine (EB-1020) Cat No HY-16736
Centanafadine is dual norepinephrine (NE)dopamine transporter inhibitor also inhibits(DA)
serotonin transporter with of 6 nM 38 nMIC s50
and 83 nM for human NE DA and serotonintransporter respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Centanafadine hydrochloride (EB-1020 hydrochloride) Cat No HY-16736A
Centanafadine (hydrochloride) is dual transporternorepinephrine (NE)dopamine (DA)
inhibitor also inhibits serotonin transporterwith of 6 nM 38 nM and 83 nM for human NEIC s50
DA and serotonin transporter respectively
Purity 9993Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
CGP 20712 A (CGP 20712 mesylate) Cat No HY-101355B
CGP 20712 A (CGP 20712 mesylate) is a highlyselective ltBgtβ1-adrenoceptorltBgtantagonist with an of 07 nM CGP 20712 AIC50
exhibits ~10000-fold selectivity overβ2-adrenoceptors
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
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Cicloprolol hydrochlorideCat No HY-U00066
Cicloprolol is a partial β 1-adrenoceptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimaterol-D7Cat No HY-100935S
Cimaterol-D7 is the deuterium labeled CimaterolCimaterol is a potent agonist of β-adrenergicreceptors (pEC s=813 878 and 662 for human50
β1 β2 and β3 respectively) Cimaterol has beenused in farmed animals to increase carcass massand to alter muscle and fat deposition
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimbuterol-D9Cat No HY-131105S
Cimbuterol-D9 is the deuterium labeled CimbuterolCimbuterol is aβ-adrenergic agonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
CL 316243Cat No HY-116771A
CL316243 is a highly potent selective agonist with a of 3 nMβ3-adrenoceptor EC50
but is an extremely poor toβ12- receptors
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg
ClenproperolCat No HY-100699
Clenproperol is a agonistβ2-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clenproperol-D7Cat No HY-100699S
Clenproperol-D7 is the deuterium labeledClenproperol Clenproperol is a β2-adrenergicagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ClonidineCat No HY-12721
Clonidine is an agonist which isalpha 2-adrenergicused extensively in anesthesia research
Purity 9879Clinical Data LaunchedSize 1 mg 5 mg
Clonidine hydrochlorideCat No HY-B0409A
Clonidine hydrochloride is an agonist of and potent antihypertensiveα2-adrenoceptor
agent
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Clorprenaline D7Cat No HY-131106S
Clorprenaline D7 is a deuterium labeledClorprenaline Clorprenaline is a β2-adrenergic
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clorprenaline hydrochlorideCat No HY-B1347
Clorprenaline hydrochloride is a β -adrenergic2
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
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D2343Cat No HY-U00206
D2343 is a agonist and also is anβ2-adrenoceptor inhibitorα1- adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Dabuzalgron (Ro 115-1240) Cat No HY-117071
Dabuzalgron (Ro 115-1240) is an orally active andselective agonist forα-1A adrenergic receptorthe treatment of urinary incontinence Dabuzalgronprotects against Doxorubicin-inducedcardiotoxicity by preserving mitochondrialfunction
Purity 9872Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Dapiprazole hydrochlorideCat No HY-A0142A
Dapiprazole hydrochloride is a potent α-adrenergicblocking drug which is used to reverse mydriasisafter eye examination
Purity 9997Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
Deriglidole (SL 86-0715) Cat No HY-101683
Deriglidole is a peripheral adrenoceptorantagonist with a high affinity forα -adrenoceptors2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DetomidineCat No HY-B0163
Detomidine produce dose-dependent sedative andanalgesic effects is a nonnarcotic syntheticα2-adrenergic agonist Target α2-adrenergicagonist Detomidine is an imidazole derivative andα2-adrenergic agonist used as a large animalsedative primarily used in horses
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Detomidine carboxylic acidCat No HY-135895
Detomidine carboxylic acid is the major urinarymetabolite of Detomidine Detomidine is asynthetic agonist and an animalα2-adrenergicanalgesic sedative Detomidine also has cardiacand respiratory effects and an antidiureticaction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Detomidine hydrochlorideCat No HY-B0163A
Detomidine hydrochloride produce dose-dependentsedative and analgesic effects is a nonnarcoticsynthetic α2-adrenergic agonist Targetα2-adrenergic agonist Detomidine is an imidazolederivative and α2-adrenergic agonist used as alarge animal sedative primarily used inhellip
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Dexmedetomidine hydrochloride ((+)-Medetomidine
hydrochloride (S)-Medetomidine hydrochloride) Cat No HY-17034A
Dexmedetomidine Hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9854Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg
Diacetolol D7Cat No HY-100635S
Diacetolol D7 is a deuterium labeled DiacetololDiacetolol is the major metabolite of AcebutololDiacetolol is a blocking andβ-adrenoceptoranti-arrhythmic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DicentrineCat No HY-N6969
Dicentrine is a natural product isolated from theplant with antihypertensiveLindera megaphyllaeffect Dicentrine is an α -adrenoceptor1
antagonist which has effective against humanhyperplastic prostates
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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DL-Epinephrine ((plusmn)-Epinephrine DL-Adrenaline (plusmn)-Adrenaline) Cat No HY-B0447
DL-Epinephrine is the racemate of epinephrineL-Epinephrine is a hormone secreted by the medullaof the adrenal glands L-Epinephrine is an
and receptor agonistα-adrenergic β-adrenergic
Purity gt990Clinical Data No Development ReportedSize 500 mg 1 g 5 g
DL-Norepinephrine hydrochlorideCat No HY-N7142
DL-Norepinephrine hydrochloride is a syntheticphenylethylamine that mimics the sympathomimeticactions of the endogenousnorepinephrineDL-Norepinephrine hydrochloride isa neurotransmitter targets α1 and β1
has an increasing effecthellipadrenoceptors
Purity 9953Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Dobutamine hydrochlorideCat No HY-15746
Dobutamine hydrochloride is a syntheticcatecholamine that acts on α1-AR β1-AR β2-AR
Dobutamine(α-1 β-1 andβ-2 adrenoceptors)hydrochloride is a selective β1-AR agonistrelatively weak activity at α1-AR and β2-AR
Purity 9947Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Dopexamine hydrochloride (FPL60278AR) Cat No HY-U00205
Dopexamine hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin (UK 33274) Cat No HY-B0098
Doxazosin (UK 33274) is a quinazoline-derivativethat selectively antagonizes postsynaptic
α1-adrenergic receptors
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin D8 (UK 33274 D8) Cat No HY-B0098S
Doxazosin D8 (UK 33274 D8) is a deuterium labeledDoxazosin (UK 33274) Doxazosin is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1 adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Doxazosin mesylate (UK 33274 mesylate) Cat No HY-B0098A
Doxazosin mesylate (UK 33274) is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1-adrenergic receptors
Purity 9860Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
EcastololCat No HY-101691
Ecastolol is a beta adrenergic receptorantagonist with antianginal activities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Epanolol (Visacor ICI141292) Cat No HY-U00183
Epanolol (Visacor ICI141292) is a potent partial agonist with a greaterβ-adrenoceptor
affinity for - than β2-adrenoceptorsβ1
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Esmolol hydrochlorideCat No HY-B1392
Esmolol hydrochloride is a beta adrenergicreceptor blocker
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
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Falintolol (Z)-Cat No HY-U00283
Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oximefunction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenmetozole TosylateCat No HY-U00402
Fenmetozole Tosylate is an antagonist of theactions of ethanol also antagonizes α2-adrenergic
and acts as an antidepressant drugreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenoterol (Th-1165 Phenoterol) Cat No HY-B0976
Fenoterol is a β 2 adrenergic agonist designed toopen up the airways to the lungs is classed assympathomimetic β2 agonist and asthma medication
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Fenoterol hydrobromide (Fenoterol bromide Th-1165a Phenoterol hydrobromide) Cat No HY-B0976A
Fenoterol hydrobromide is a β 2 adrenergic agonistdesigned to open up the airways to the lungs isclassed as sympathomimetic β2 agonist and asthmamedication
Purity 9971Clinical Data LaunchedSize 100 mg
Fenspiride HydrochlorideCat No HY-A0027
Fenspiride Hcl is an α adrenergic and H1 histaminereceptor antagonist IC50 value TargetAdrenergic receptor H1 receptor Fenspiridehydrochloride is a bronchodilator withanti-inflammatory properties
Purity 9903Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
FiduxosinCat No HY-U00399
Fiduxosin is a potent antagonistα1-adrenoceptorwith of 0160 nM 249 nM and 0920 nM forKi
α1a- α1b- and α1d-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg
Formoterol Fumarate (Formoterol) Cat No HY-B0010
Formoterol fumarate(Foradil) is a potentselective and long-acting β2-adrenoceptor agonist
Purity 9894Clinical Data LaunchedSize 10 mg 50 mg
G-Protein antagonist peptideCat No HY-P1376
G-Protein antagonist peptide is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
G-Protein antagonist peptide TFACat No HY-P1376A
G-Protein antagonist peptide TFA is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide TFA competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Glaucine (OO-Dimethylisoboldine S-(+)-Glaucine NSC 34396) Cat No HY-N3945
Glaucine (OO-Dimethylisoboldine) is an alkaloidisolated from Crantz withGlaucium flavumantitussive bronchodilation and anti-inflammatoryproperties
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 11
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
16 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
18 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
20 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Adrenergic Receptor Agonists Antagonists Inhibitors Activators amp Modulators
(+)-Penbutolol ((R)-Penbutolol (+)-Isopenbutolol) Cat No HY-116790A
(+)-Penbutolol is a β-adrenoceptor antagonistwith an IC of 074 μM (+)-Penbutolol is an50
optical isomer of l-penbutolol with Na+
channel-blocking action
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
(4E)-SUN9221Cat No HY-U00367
(4E)-SUN9221 is a potent antagonist of and withα1-adrenergic receptor 5-HT2 receptor
antihypertensive and anti-platelet aggregationactivities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
(R)-(+)-AtenololCat No HY-B2111
(R)-(+)-Atenolol is the less active enantiomer ofthe (RS)-atenolol (RS)-atenolol is aβ-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg
(R)-Carvedilol ((R)-BM 14190) Cat No HY-B0006C
(R)-Carvedilol ((R)-BM 14190) the R-enantiomer ofCarvedilol is a non-selective blockerβα-1(R)-Carvedilol exerts protection against thevascular or cardiac toxicity of Doxorubicin (DOX)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
(R)-TerazosinCat No HY-B0371B
(R)-Terazosin is an active R-enantiomer ofTerazosin (R)-Terazosin is a potent
antagonist with values of 651α1-adrenoceptor Ki
nM 101 nM and 197 nM for andα1a α1b respectivelyα1d-adrenoceptor
Purity 9977Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
(Rac)-Rotigotine hydrochlorideCat No HY-15394
(Rac)-Rotigotine hydrochloride is a racemate ofRotigotine
Purity 9776Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
(RS)-ButyryltimololCat No HY-102032A
(RS)-Butyryltimolol is the racemate ofButyryltimolol Butyryltimolol an effectiveprodrug of Timolol improves the cornealpenetration of Timolol Butyryltimolol is aβ-adrenergic blocker
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
(S)-Carvedilol ((S)-BM 14190) Cat No HY-B0006B
(S)-Carvedilol the S-enantiomer of Carvedilol isa non-selective blocker (S)-Carvedilolβα-1exerts protection against the vascular or cardiactoxicity of Doxorubicin (DOX)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
(S)-TerazosinCat No HY-B0371D
(S)-Terazosin is an active S-enantiomer ofTerazosin (S)-Terazosin is a potent andhigh-affinity antagonist with α-adrenoceptor Ki
values of 391 nM 079 nM and 116 nM for α1a and respectivelyα1b α1d-adrenoceptor
Purity 9977Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
(S)-Timolol Maleate (L-714465 Maleate MK 950) Cat No HY-17380
(S)-Timolol Maleate (L-714465 Maleate) is anon-cardioselective hydrophilic β-adrenoceptorblocker (S)-Timolol Maleate is widely used asstandard medication for intraocular pressure(glaucoma) by preventing the production of aqueoushumor
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg
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(plusmn)-BefunololCat No HY-101752
(plusmn)-Befunolol is a blocking agentβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
(plusmn)-Bisoprolol hemifumarate (Bisoprolol hemifumarate salt) Cat No HY-B0076
(plusmn)-Bisoprolol (hemifumarate) is a selective typeβ1 adrenergic receptor blocker Target AdrenergicReceptor Approved July 31 1992 Bisoprolol onbeta 1-adrenoceptor peptide induced autoimmunemyocardial damage
Purity 9965Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
25-DideoxyadenosineCat No HY-135878
25-Dideoxyadenosine is a potent andnon-competitive inhibitor viaadenylyl cyclasebinding the P-site with an of 3 microM IC50
25-Dideoxyadenosine is a nucleoside analog andexerts a potent action in heartantiadrenergic
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg 100 mg 250 mg
4-Hydroxypropranolol D7 hydrochloride ((plusmn)-4-hydroxy Propranolol D7 hydrochloride) Cat No HY-100634S
4-Hydroxypropranolol D7 hydrochloride((plusmn)-4-hydroxy Propranolol D7 hydrochloride) is adeuterium labeled 4-Hydroxypropranololhydrochloride
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
4-Hydroxypropranolol hydrochloride ((plusmn)-4-hydroxy Propranolol hydrochloride) Cat No HY-100634
4-Hydroxypropranolol hydrochlorid is an activemetabolite of Propranolol 4-Hydroxypropranololhydrochlorid is of comparable potency toPropranolol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
5-HT2 antagonist 1Cat No HY-U00365
5-HT2 antagonist 1 is a potent antagonist of with weak 5-HT2 receptor α1 adrenoceptor
blocking activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
AaptamineCat No HY-N4225
Aaptamine a spongean alkaloid isolated from a seasponge Aaptos aaptos is a competitive antagonistof and activates the p21 promoterα-adrenoceptorin a p53-independent manner
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Acebutolol D7Cat No HY-17497S
Acebutolol D7 is a deuterium labeled AcebutololAcebutolol is a selective β1 adrenergic receptorantagonist used in the treatment of hypertensionangina pectoris and cardiac arrhythmias
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Acebutolol hydrochlorideCat No HY-17497A
Acebutolol hydrochloride is a β1 adrenergic antagonist Acebutololreceptor (β1AR)
hydrochloride is used in the treatment ofhypertension angina pectoris and cardiacarrhythmias
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 5 g 10 g
ACTH (1-14) (Adrenocorticotropic Hormone Fragment 1-14) Cat No HY-P1582
ACTH (1-14) is a fragment of adrenocorticotrophinwhich regulates cortisol and androgen production
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 3
ACTH (1-14) (TFA) (Adrenocorticotropic Hormone Fragment 1-14 TFA) Cat No HY-P1582A
ACTH (1-14) (TFA) is a fragment ofadrenocorticotrophin which regulates cortisol andandrogen production
Purity 9855Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg
ADRA1D receptor agonist 1Cat No HY-135270
ADRA1D receptor agonist 1 (compound (R)-9S) is apotent selective and orally active α1D
antagonist with a of 16 nMadrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
AGN 192836Cat No HY-100300
AGN 192836 is a potent and selective α2 adrenergicagonist with s of 87 41 and 66 nM forEC50
α2A α2B and α2C receptor respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ajmalicine (Raubasine) Cat No HY-N1919
Ajmalicine (Raubasine) is found in herbs ofCatharanthus roseus is an antihypertensive drugused in the treatment of high blood pressuredecreases peripheral resistance and bloodpressure
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Alfuzosin (SL 77499) Cat No HY-B0192
Alfuzosin is an α1 adrenergic receptor antagonistused to treat benign prostatic hyperplasia (BPH)
Purity 9981Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Alfuzosin hydrochloride (SL 77499-10) Cat No HY-B0192A
Alfuzosin hydrochloride is an α1 adrenergicreceptor antagonist used to treat benign prostatichyperplasia (BPH)
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Amezinium methylsulfate (Amezinium metilsulfate Lu-1631) Cat No HY-A0275
Amezinium metilsulfate has multiple mechanismsincluding stimulation of alpha and beta-1receptors and inhibition ofnoradrenaline andtyramine uptake
Purity 9951Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
Amibegron hydrochloride (SR 58611A) Cat No HY-103207
Amibegron hydrochloride is a selective agonist with an of 35 nMβ3-adrenoceptor EC50
for in rat colon Amibegronβ-adrenoceptorhydrochloride has anxiolytic and antidepressantactivity
Purity gt990Clinical Data No Development ReportedSize 5 mg
Amitraz (BTS-27419) Cat No HY-B1111
Amitraz is a non-systemic acaricide andinsecticide with alpha-adrenergic agonistactivity interaction with octopamine receptors ofthe central nervous system and inhibition ofmonoamine oxidases and prostaglandin synthesis
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
AncarololCat No HY-100141
Ancarolol is a blocking agentbeta-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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AR-08Cat No HY-U00371
AR-08 is an agonist of α2-adrenergic receptorused for the treatment of attention deficithyperactivety disorder (ADHD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ArbutamineCat No HY-16056
Arbutamine is a short-acting synthetic potentnonselective agonist thatβ-adrenoceptorincreases heart rate cardiac contractility andsystolic blood pressure Arbutamine is acatecholamine for a pharmacological cardiac stressagen
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
ArotinololCat No HY-122537A
Arotinolol is a nonselective αβ-adrenergic blocker and a vasodilating β-blockerreceptor
Arotinolol also shows potency for inhibiting thebinding of the radioligand I-ICYP to125
-serotonergic receptor sites5HT1B
Purity 9818Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Asenapine (Org 5222) Cat No HY-10121
Asenapine(Org 5222) inhibits adrenergic receptor(α1 α2A α2B α2C) with Ki of 025-12 nM andalso inhibits 5-HT receptor (1A 1B 2A 2B 2C5A 6 7) with Ki of 003-40 nM
Purity 9881Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Atenolol ((RS)-Atenolol) Cat No HY-17498
Atenolol is a selective β1 receptor antagonistTarget Adrenergic Receptor Atenolol is acardioselective beta-adrenergic blocker possessingproperties and potency similar to propranolol butwithout a negative inotropic effect [1 2]
Purity 9961Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Atipamezole (MPV 1248) Cat No HY-12380A
Atipamezole is a synthetic α -adrenoceptor2
with a of 16 nMantagonist Ki
Purity 9948Clinical Data Phase 1Size 10 mM times 1 mL 10 mg 50 mg
Atipamezole hydrochloride (MPV-1248 hydrochloride) Cat No HY-12380
Atipamezole hydrochloride is a synthetic with a of 16 nMα -adrenoceptor antagonist2 Ki
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Bambuterol ((plusmn)-Bambuterol KWD-2183) Cat No HY-17501
Bambuterol ((plusmn)-Bambuterol KWD-2183) is a longacting beta-adrenoceptor agonist (LABA) used inthe treatment of asthma it also is a prodrug ofterbutaline
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Bambuterol hydrochloride ((plusmn)-Bambuterol hydrochloride KWD-2183 hydrochloride) Cat No HY-17501A
Bambuterol hydrochloride ((plusmn)-Bambuterolhydrochloride KWD-2183 hydrochloride) is a longacting beta-adrenoceptor agonist (LABA) used inthe treatment of asthma it also is a prodrug ofterbutaline
Purity 9957Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Batefenterol (GSK961081 TD-5959) Cat No HY-12980
Batefenterol (GSK961081TD-5959) is a novel receptor antagonist andmuscarinic
agonist displays high affinityβ -adrenoceptor2
for hM2 hM3 muscarinic and hβ -adrenoceptor with2
values of 14 13 and 37 nM respectivelyKi
Purity 9817Clinical Data Phase 2Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 5
Benzquinamide (P2647 BZQ Benzoquinamide) Cat No HY-U00244
Benzquinamide (P2647) is an antiemetic which canbind to the and α2A α2B α2C adrenergic
(α2-AR) with K values of 1365 691receptors i
and 545 nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BetaxololCat No HY-B0381
Betaxolol is a selective beta1 adrenergic receptorblocker used in the treatment of hypertension andglaucoma Target Beta1 Adrenergic ReceptorBetaxolol is a cardioselective beta-adrenergicreceptor blocking agent Betaxolol (5 mgkg viaip
Purity 9695Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Betaxolol hydrochloride (SL75212) Cat No HY-B0381A
Betaxolol Hydrochloride is a selective beta1adrenergic receptor blocker used in the treatmentof hypertension and glaucoma Target Beta1Adrenergic Receptor Betaxolol hydrochloride is acardioselective beta-adrenergic receptor blockingagent
Purity 9894Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Bevantolol hydrochlorideCat No HY-121186
Bevantolol hydrochloride is a selective andβ1α1-adrenergic receptor antagonist with valuespKi
of 783 69 in rat cerebral cortex respectivelyBevantolol hydrochloride is a potent Ca2+
antagonist
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 25 mg 50 mg 100 mg
BI-167107Cat No HY-121251
BI-167107 is a high affinity full agonist thatbinds to the β2 adrenergic receptor ( ) with aβ2ARdissociation constant of 84 pMKd
Purity 9981Clinical DataSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Bometolol HydrochlorideCat No HY-U00386
Bometolol Hydrochloride is a beta-adrenergicblocking agent used for the research ofcardiovascular disease
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brimonidine (UK 14304 AGN190342) Cat No HY-B0659
Brimonidine (UK 14304) is a full α2-adrenergicreceptor (α2-AR) agonist
Purity 9965Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Brimonidine tartrate (UK 14304 tartrate AGN190342 tartrate) Cat No HY-B0659A
Brimonidine tartrate (UK 14304 tartrate) is a fullα2-adrenergic receptor (α2-AR) agonist
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
BRL 37344 sodium (BRL 37344A) Cat No HY-101325
BRL 37344 sodium (BRL 37344A) is a specific agonist BRL 37344 sodiumβ3-adrenergic receptor
treatment significantly lowers the body weight ofobese mice
Purity gt990Clinical Data No Development ReportedSize 1 mg
Brombuterol D9 (Bromobuterol D9) Cat No HY-131104S
Brombuterol D9 (Bromobuterol D9) is a deuteriumlabeled Brombuterol Brombuterol is a β-adrenergic
agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Brombuterol D9 hydrochloride (Bromobuterol D9 hydrochloride) Cat No HY-131104AS
Brombuterol D9 hydrochloride (Bromobuterol D9hydrochloride) is a deuterium labeled Brombuterolhydrochloride Brombuterol hydrochloride is a
agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brombuterol hydrochloride (Bromobuterol hydrochloride) Cat No HY-131145
Brombuterol hydrochloride (Bromobuterolhydrochloride) is a agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BucindololCat No HY-103214
Bucindolol is a blockerβ1-adrenergic receptorwith intrinsic sympathomimetic activity used inthe research of heart failure
Purity gt990Clinical Data No Development ReportedSize 1 mg 5 mg
Carbazochrome sodium sulfonate (AC-17) Cat No HY-B0491A
Carbazochrome (sodium sulfonate) (AC-17) is anantihemorrhagic agent
Purity 9951Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carteolol hydrochloride (OPC-1085 hydrochloride) Cat No HY-17495A
Carteolol hydrochloride (OPC-1085 hydrochloride)is a non-selective beta blocker used to treatglaucoma
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carvedilol (BM 14190) Cat No HY-B0006
Carvedilol (BM 14190) is a non-selective βα-1blocker Carvedilol inhibits lipid peroxidation ina dose-dependent manner with an IC of 5 μM50
Carvedilol is a multiple action antihypertensiveagent with potential use in angina and congestiveheart failure
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) Cat No HY-B0006A
Carvedilol phosphate hemihydrate (BM 14190phosphate hemihydrate) is a non-selective βα-1blocker Carvedilol phosphate hemihydrate inhibits
with an IC of 5 μMlipid peroxidation 50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Centanafadine (EB-1020) Cat No HY-16736
Centanafadine is dual norepinephrine (NE)dopamine transporter inhibitor also inhibits(DA)
serotonin transporter with of 6 nM 38 nMIC s50
and 83 nM for human NE DA and serotonintransporter respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Centanafadine hydrochloride (EB-1020 hydrochloride) Cat No HY-16736A
Centanafadine (hydrochloride) is dual transporternorepinephrine (NE)dopamine (DA)
inhibitor also inhibits serotonin transporterwith of 6 nM 38 nM and 83 nM for human NEIC s50
DA and serotonin transporter respectively
Purity 9993Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
CGP 20712 A (CGP 20712 mesylate) Cat No HY-101355B
CGP 20712 A (CGP 20712 mesylate) is a highlyselective ltBgtβ1-adrenoceptorltBgtantagonist with an of 07 nM CGP 20712 AIC50
exhibits ~10000-fold selectivity overβ2-adrenoceptors
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
wwwMedChemExpresscom 7
Cicloprolol hydrochlorideCat No HY-U00066
Cicloprolol is a partial β 1-adrenoceptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimaterol-D7Cat No HY-100935S
Cimaterol-D7 is the deuterium labeled CimaterolCimaterol is a potent agonist of β-adrenergicreceptors (pEC s=813 878 and 662 for human50
β1 β2 and β3 respectively) Cimaterol has beenused in farmed animals to increase carcass massand to alter muscle and fat deposition
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimbuterol-D9Cat No HY-131105S
Cimbuterol-D9 is the deuterium labeled CimbuterolCimbuterol is aβ-adrenergic agonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
CL 316243Cat No HY-116771A
CL316243 is a highly potent selective agonist with a of 3 nMβ3-adrenoceptor EC50
but is an extremely poor toβ12- receptors
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg
ClenproperolCat No HY-100699
Clenproperol is a agonistβ2-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clenproperol-D7Cat No HY-100699S
Clenproperol-D7 is the deuterium labeledClenproperol Clenproperol is a β2-adrenergicagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ClonidineCat No HY-12721
Clonidine is an agonist which isalpha 2-adrenergicused extensively in anesthesia research
Purity 9879Clinical Data LaunchedSize 1 mg 5 mg
Clonidine hydrochlorideCat No HY-B0409A
Clonidine hydrochloride is an agonist of and potent antihypertensiveα2-adrenoceptor
agent
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Clorprenaline D7Cat No HY-131106S
Clorprenaline D7 is a deuterium labeledClorprenaline Clorprenaline is a β2-adrenergic
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clorprenaline hydrochlorideCat No HY-B1347
Clorprenaline hydrochloride is a β -adrenergic2
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
8 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
D2343Cat No HY-U00206
D2343 is a agonist and also is anβ2-adrenoceptor inhibitorα1- adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Dabuzalgron (Ro 115-1240) Cat No HY-117071
Dabuzalgron (Ro 115-1240) is an orally active andselective agonist forα-1A adrenergic receptorthe treatment of urinary incontinence Dabuzalgronprotects against Doxorubicin-inducedcardiotoxicity by preserving mitochondrialfunction
Purity 9872Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Dapiprazole hydrochlorideCat No HY-A0142A
Dapiprazole hydrochloride is a potent α-adrenergicblocking drug which is used to reverse mydriasisafter eye examination
Purity 9997Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
Deriglidole (SL 86-0715) Cat No HY-101683
Deriglidole is a peripheral adrenoceptorantagonist with a high affinity forα -adrenoceptors2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DetomidineCat No HY-B0163
Detomidine produce dose-dependent sedative andanalgesic effects is a nonnarcotic syntheticα2-adrenergic agonist Target α2-adrenergicagonist Detomidine is an imidazole derivative andα2-adrenergic agonist used as a large animalsedative primarily used in horses
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Detomidine carboxylic acidCat No HY-135895
Detomidine carboxylic acid is the major urinarymetabolite of Detomidine Detomidine is asynthetic agonist and an animalα2-adrenergicanalgesic sedative Detomidine also has cardiacand respiratory effects and an antidiureticaction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Detomidine hydrochlorideCat No HY-B0163A
Detomidine hydrochloride produce dose-dependentsedative and analgesic effects is a nonnarcoticsynthetic α2-adrenergic agonist Targetα2-adrenergic agonist Detomidine is an imidazolederivative and α2-adrenergic agonist used as alarge animal sedative primarily used inhellip
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Dexmedetomidine hydrochloride ((+)-Medetomidine
hydrochloride (S)-Medetomidine hydrochloride) Cat No HY-17034A
Dexmedetomidine Hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9854Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg
Diacetolol D7Cat No HY-100635S
Diacetolol D7 is a deuterium labeled DiacetololDiacetolol is the major metabolite of AcebutololDiacetolol is a blocking andβ-adrenoceptoranti-arrhythmic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DicentrineCat No HY-N6969
Dicentrine is a natural product isolated from theplant with antihypertensiveLindera megaphyllaeffect Dicentrine is an α -adrenoceptor1
antagonist which has effective against humanhyperplastic prostates
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 9
DL-Epinephrine ((plusmn)-Epinephrine DL-Adrenaline (plusmn)-Adrenaline) Cat No HY-B0447
DL-Epinephrine is the racemate of epinephrineL-Epinephrine is a hormone secreted by the medullaof the adrenal glands L-Epinephrine is an
and receptor agonistα-adrenergic β-adrenergic
Purity gt990Clinical Data No Development ReportedSize 500 mg 1 g 5 g
DL-Norepinephrine hydrochlorideCat No HY-N7142
DL-Norepinephrine hydrochloride is a syntheticphenylethylamine that mimics the sympathomimeticactions of the endogenousnorepinephrineDL-Norepinephrine hydrochloride isa neurotransmitter targets α1 and β1
has an increasing effecthellipadrenoceptors
Purity 9953Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Dobutamine hydrochlorideCat No HY-15746
Dobutamine hydrochloride is a syntheticcatecholamine that acts on α1-AR β1-AR β2-AR
Dobutamine(α-1 β-1 andβ-2 adrenoceptors)hydrochloride is a selective β1-AR agonistrelatively weak activity at α1-AR and β2-AR
Purity 9947Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Dopexamine hydrochloride (FPL60278AR) Cat No HY-U00205
Dopexamine hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin (UK 33274) Cat No HY-B0098
Doxazosin (UK 33274) is a quinazoline-derivativethat selectively antagonizes postsynaptic
α1-adrenergic receptors
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin D8 (UK 33274 D8) Cat No HY-B0098S
Doxazosin D8 (UK 33274 D8) is a deuterium labeledDoxazosin (UK 33274) Doxazosin is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1 adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Doxazosin mesylate (UK 33274 mesylate) Cat No HY-B0098A
Doxazosin mesylate (UK 33274) is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1-adrenergic receptors
Purity 9860Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
EcastololCat No HY-101691
Ecastolol is a beta adrenergic receptorantagonist with antianginal activities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Epanolol (Visacor ICI141292) Cat No HY-U00183
Epanolol (Visacor ICI141292) is a potent partial agonist with a greaterβ-adrenoceptor
affinity for - than β2-adrenoceptorsβ1
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Esmolol hydrochlorideCat No HY-B1392
Esmolol hydrochloride is a beta adrenergicreceptor blocker
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
10 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Falintolol (Z)-Cat No HY-U00283
Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oximefunction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenmetozole TosylateCat No HY-U00402
Fenmetozole Tosylate is an antagonist of theactions of ethanol also antagonizes α2-adrenergic
and acts as an antidepressant drugreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenoterol (Th-1165 Phenoterol) Cat No HY-B0976
Fenoterol is a β 2 adrenergic agonist designed toopen up the airways to the lungs is classed assympathomimetic β2 agonist and asthma medication
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Fenoterol hydrobromide (Fenoterol bromide Th-1165a Phenoterol hydrobromide) Cat No HY-B0976A
Fenoterol hydrobromide is a β 2 adrenergic agonistdesigned to open up the airways to the lungs isclassed as sympathomimetic β2 agonist and asthmamedication
Purity 9971Clinical Data LaunchedSize 100 mg
Fenspiride HydrochlorideCat No HY-A0027
Fenspiride Hcl is an α adrenergic and H1 histaminereceptor antagonist IC50 value TargetAdrenergic receptor H1 receptor Fenspiridehydrochloride is a bronchodilator withanti-inflammatory properties
Purity 9903Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
FiduxosinCat No HY-U00399
Fiduxosin is a potent antagonistα1-adrenoceptorwith of 0160 nM 249 nM and 0920 nM forKi
α1a- α1b- and α1d-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg
Formoterol Fumarate (Formoterol) Cat No HY-B0010
Formoterol fumarate(Foradil) is a potentselective and long-acting β2-adrenoceptor agonist
Purity 9894Clinical Data LaunchedSize 10 mg 50 mg
G-Protein antagonist peptideCat No HY-P1376
G-Protein antagonist peptide is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
G-Protein antagonist peptide TFACat No HY-P1376A
G-Protein antagonist peptide TFA is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide TFA competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Glaucine (OO-Dimethylisoboldine S-(+)-Glaucine NSC 34396) Cat No HY-N3945
Glaucine (OO-Dimethylisoboldine) is an alkaloidisolated from Crantz withGlaucium flavumantitussive bronchodilation and anti-inflammatoryproperties
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 11
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
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Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
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NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
(plusmn)-BefunololCat No HY-101752
(plusmn)-Befunolol is a blocking agentβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
(plusmn)-Bisoprolol hemifumarate (Bisoprolol hemifumarate salt) Cat No HY-B0076
(plusmn)-Bisoprolol (hemifumarate) is a selective typeβ1 adrenergic receptor blocker Target AdrenergicReceptor Approved July 31 1992 Bisoprolol onbeta 1-adrenoceptor peptide induced autoimmunemyocardial damage
Purity 9965Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
25-DideoxyadenosineCat No HY-135878
25-Dideoxyadenosine is a potent andnon-competitive inhibitor viaadenylyl cyclasebinding the P-site with an of 3 microM IC50
25-Dideoxyadenosine is a nucleoside analog andexerts a potent action in heartantiadrenergic
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg 100 mg 250 mg
4-Hydroxypropranolol D7 hydrochloride ((plusmn)-4-hydroxy Propranolol D7 hydrochloride) Cat No HY-100634S
4-Hydroxypropranolol D7 hydrochloride((plusmn)-4-hydroxy Propranolol D7 hydrochloride) is adeuterium labeled 4-Hydroxypropranololhydrochloride
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
4-Hydroxypropranolol hydrochloride ((plusmn)-4-hydroxy Propranolol hydrochloride) Cat No HY-100634
4-Hydroxypropranolol hydrochlorid is an activemetabolite of Propranolol 4-Hydroxypropranololhydrochlorid is of comparable potency toPropranolol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
5-HT2 antagonist 1Cat No HY-U00365
5-HT2 antagonist 1 is a potent antagonist of with weak 5-HT2 receptor α1 adrenoceptor
blocking activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
AaptamineCat No HY-N4225
Aaptamine a spongean alkaloid isolated from a seasponge Aaptos aaptos is a competitive antagonistof and activates the p21 promoterα-adrenoceptorin a p53-independent manner
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Acebutolol D7Cat No HY-17497S
Acebutolol D7 is a deuterium labeled AcebutololAcebutolol is a selective β1 adrenergic receptorantagonist used in the treatment of hypertensionangina pectoris and cardiac arrhythmias
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Acebutolol hydrochlorideCat No HY-17497A
Acebutolol hydrochloride is a β1 adrenergic antagonist Acebutololreceptor (β1AR)
hydrochloride is used in the treatment ofhypertension angina pectoris and cardiacarrhythmias
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 5 g 10 g
ACTH (1-14) (Adrenocorticotropic Hormone Fragment 1-14) Cat No HY-P1582
ACTH (1-14) is a fragment of adrenocorticotrophinwhich regulates cortisol and androgen production
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 3
ACTH (1-14) (TFA) (Adrenocorticotropic Hormone Fragment 1-14 TFA) Cat No HY-P1582A
ACTH (1-14) (TFA) is a fragment ofadrenocorticotrophin which regulates cortisol andandrogen production
Purity 9855Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg
ADRA1D receptor agonist 1Cat No HY-135270
ADRA1D receptor agonist 1 (compound (R)-9S) is apotent selective and orally active α1D
antagonist with a of 16 nMadrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
AGN 192836Cat No HY-100300
AGN 192836 is a potent and selective α2 adrenergicagonist with s of 87 41 and 66 nM forEC50
α2A α2B and α2C receptor respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ajmalicine (Raubasine) Cat No HY-N1919
Ajmalicine (Raubasine) is found in herbs ofCatharanthus roseus is an antihypertensive drugused in the treatment of high blood pressuredecreases peripheral resistance and bloodpressure
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Alfuzosin (SL 77499) Cat No HY-B0192
Alfuzosin is an α1 adrenergic receptor antagonistused to treat benign prostatic hyperplasia (BPH)
Purity 9981Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Alfuzosin hydrochloride (SL 77499-10) Cat No HY-B0192A
Alfuzosin hydrochloride is an α1 adrenergicreceptor antagonist used to treat benign prostatichyperplasia (BPH)
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Amezinium methylsulfate (Amezinium metilsulfate Lu-1631) Cat No HY-A0275
Amezinium metilsulfate has multiple mechanismsincluding stimulation of alpha and beta-1receptors and inhibition ofnoradrenaline andtyramine uptake
Purity 9951Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
Amibegron hydrochloride (SR 58611A) Cat No HY-103207
Amibegron hydrochloride is a selective agonist with an of 35 nMβ3-adrenoceptor EC50
for in rat colon Amibegronβ-adrenoceptorhydrochloride has anxiolytic and antidepressantactivity
Purity gt990Clinical Data No Development ReportedSize 5 mg
Amitraz (BTS-27419) Cat No HY-B1111
Amitraz is a non-systemic acaricide andinsecticide with alpha-adrenergic agonistactivity interaction with octopamine receptors ofthe central nervous system and inhibition ofmonoamine oxidases and prostaglandin synthesis
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
AncarololCat No HY-100141
Ancarolol is a blocking agentbeta-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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AR-08Cat No HY-U00371
AR-08 is an agonist of α2-adrenergic receptorused for the treatment of attention deficithyperactivety disorder (ADHD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ArbutamineCat No HY-16056
Arbutamine is a short-acting synthetic potentnonselective agonist thatβ-adrenoceptorincreases heart rate cardiac contractility andsystolic blood pressure Arbutamine is acatecholamine for a pharmacological cardiac stressagen
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
ArotinololCat No HY-122537A
Arotinolol is a nonselective αβ-adrenergic blocker and a vasodilating β-blockerreceptor
Arotinolol also shows potency for inhibiting thebinding of the radioligand I-ICYP to125
-serotonergic receptor sites5HT1B
Purity 9818Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Asenapine (Org 5222) Cat No HY-10121
Asenapine(Org 5222) inhibits adrenergic receptor(α1 α2A α2B α2C) with Ki of 025-12 nM andalso inhibits 5-HT receptor (1A 1B 2A 2B 2C5A 6 7) with Ki of 003-40 nM
Purity 9881Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Atenolol ((RS)-Atenolol) Cat No HY-17498
Atenolol is a selective β1 receptor antagonistTarget Adrenergic Receptor Atenolol is acardioselective beta-adrenergic blocker possessingproperties and potency similar to propranolol butwithout a negative inotropic effect [1 2]
Purity 9961Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Atipamezole (MPV 1248) Cat No HY-12380A
Atipamezole is a synthetic α -adrenoceptor2
with a of 16 nMantagonist Ki
Purity 9948Clinical Data Phase 1Size 10 mM times 1 mL 10 mg 50 mg
Atipamezole hydrochloride (MPV-1248 hydrochloride) Cat No HY-12380
Atipamezole hydrochloride is a synthetic with a of 16 nMα -adrenoceptor antagonist2 Ki
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Bambuterol ((plusmn)-Bambuterol KWD-2183) Cat No HY-17501
Bambuterol ((plusmn)-Bambuterol KWD-2183) is a longacting beta-adrenoceptor agonist (LABA) used inthe treatment of asthma it also is a prodrug ofterbutaline
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Bambuterol hydrochloride ((plusmn)-Bambuterol hydrochloride KWD-2183 hydrochloride) Cat No HY-17501A
Bambuterol hydrochloride ((plusmn)-Bambuterolhydrochloride KWD-2183 hydrochloride) is a longacting beta-adrenoceptor agonist (LABA) used inthe treatment of asthma it also is a prodrug ofterbutaline
Purity 9957Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Batefenterol (GSK961081 TD-5959) Cat No HY-12980
Batefenterol (GSK961081TD-5959) is a novel receptor antagonist andmuscarinic
agonist displays high affinityβ -adrenoceptor2
for hM2 hM3 muscarinic and hβ -adrenoceptor with2
values of 14 13 and 37 nM respectivelyKi
Purity 9817Clinical Data Phase 2Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
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Benzquinamide (P2647 BZQ Benzoquinamide) Cat No HY-U00244
Benzquinamide (P2647) is an antiemetic which canbind to the and α2A α2B α2C adrenergic
(α2-AR) with K values of 1365 691receptors i
and 545 nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BetaxololCat No HY-B0381
Betaxolol is a selective beta1 adrenergic receptorblocker used in the treatment of hypertension andglaucoma Target Beta1 Adrenergic ReceptorBetaxolol is a cardioselective beta-adrenergicreceptor blocking agent Betaxolol (5 mgkg viaip
Purity 9695Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Betaxolol hydrochloride (SL75212) Cat No HY-B0381A
Betaxolol Hydrochloride is a selective beta1adrenergic receptor blocker used in the treatmentof hypertension and glaucoma Target Beta1Adrenergic Receptor Betaxolol hydrochloride is acardioselective beta-adrenergic receptor blockingagent
Purity 9894Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Bevantolol hydrochlorideCat No HY-121186
Bevantolol hydrochloride is a selective andβ1α1-adrenergic receptor antagonist with valuespKi
of 783 69 in rat cerebral cortex respectivelyBevantolol hydrochloride is a potent Ca2+
antagonist
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 25 mg 50 mg 100 mg
BI-167107Cat No HY-121251
BI-167107 is a high affinity full agonist thatbinds to the β2 adrenergic receptor ( ) with aβ2ARdissociation constant of 84 pMKd
Purity 9981Clinical DataSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Bometolol HydrochlorideCat No HY-U00386
Bometolol Hydrochloride is a beta-adrenergicblocking agent used for the research ofcardiovascular disease
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brimonidine (UK 14304 AGN190342) Cat No HY-B0659
Brimonidine (UK 14304) is a full α2-adrenergicreceptor (α2-AR) agonist
Purity 9965Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Brimonidine tartrate (UK 14304 tartrate AGN190342 tartrate) Cat No HY-B0659A
Brimonidine tartrate (UK 14304 tartrate) is a fullα2-adrenergic receptor (α2-AR) agonist
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
BRL 37344 sodium (BRL 37344A) Cat No HY-101325
BRL 37344 sodium (BRL 37344A) is a specific agonist BRL 37344 sodiumβ3-adrenergic receptor
treatment significantly lowers the body weight ofobese mice
Purity gt990Clinical Data No Development ReportedSize 1 mg
Brombuterol D9 (Bromobuterol D9) Cat No HY-131104S
Brombuterol D9 (Bromobuterol D9) is a deuteriumlabeled Brombuterol Brombuterol is a β-adrenergic
agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Brombuterol D9 hydrochloride (Bromobuterol D9 hydrochloride) Cat No HY-131104AS
Brombuterol D9 hydrochloride (Bromobuterol D9hydrochloride) is a deuterium labeled Brombuterolhydrochloride Brombuterol hydrochloride is a
agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brombuterol hydrochloride (Bromobuterol hydrochloride) Cat No HY-131145
Brombuterol hydrochloride (Bromobuterolhydrochloride) is a agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BucindololCat No HY-103214
Bucindolol is a blockerβ1-adrenergic receptorwith intrinsic sympathomimetic activity used inthe research of heart failure
Purity gt990Clinical Data No Development ReportedSize 1 mg 5 mg
Carbazochrome sodium sulfonate (AC-17) Cat No HY-B0491A
Carbazochrome (sodium sulfonate) (AC-17) is anantihemorrhagic agent
Purity 9951Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carteolol hydrochloride (OPC-1085 hydrochloride) Cat No HY-17495A
Carteolol hydrochloride (OPC-1085 hydrochloride)is a non-selective beta blocker used to treatglaucoma
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carvedilol (BM 14190) Cat No HY-B0006
Carvedilol (BM 14190) is a non-selective βα-1blocker Carvedilol inhibits lipid peroxidation ina dose-dependent manner with an IC of 5 μM50
Carvedilol is a multiple action antihypertensiveagent with potential use in angina and congestiveheart failure
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) Cat No HY-B0006A
Carvedilol phosphate hemihydrate (BM 14190phosphate hemihydrate) is a non-selective βα-1blocker Carvedilol phosphate hemihydrate inhibits
with an IC of 5 μMlipid peroxidation 50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Centanafadine (EB-1020) Cat No HY-16736
Centanafadine is dual norepinephrine (NE)dopamine transporter inhibitor also inhibits(DA)
serotonin transporter with of 6 nM 38 nMIC s50
and 83 nM for human NE DA and serotonintransporter respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Centanafadine hydrochloride (EB-1020 hydrochloride) Cat No HY-16736A
Centanafadine (hydrochloride) is dual transporternorepinephrine (NE)dopamine (DA)
inhibitor also inhibits serotonin transporterwith of 6 nM 38 nM and 83 nM for human NEIC s50
DA and serotonin transporter respectively
Purity 9993Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
CGP 20712 A (CGP 20712 mesylate) Cat No HY-101355B
CGP 20712 A (CGP 20712 mesylate) is a highlyselective ltBgtβ1-adrenoceptorltBgtantagonist with an of 07 nM CGP 20712 AIC50
exhibits ~10000-fold selectivity overβ2-adrenoceptors
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
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Cicloprolol hydrochlorideCat No HY-U00066
Cicloprolol is a partial β 1-adrenoceptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimaterol-D7Cat No HY-100935S
Cimaterol-D7 is the deuterium labeled CimaterolCimaterol is a potent agonist of β-adrenergicreceptors (pEC s=813 878 and 662 for human50
β1 β2 and β3 respectively) Cimaterol has beenused in farmed animals to increase carcass massand to alter muscle and fat deposition
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimbuterol-D9Cat No HY-131105S
Cimbuterol-D9 is the deuterium labeled CimbuterolCimbuterol is aβ-adrenergic agonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
CL 316243Cat No HY-116771A
CL316243 is a highly potent selective agonist with a of 3 nMβ3-adrenoceptor EC50
but is an extremely poor toβ12- receptors
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg
ClenproperolCat No HY-100699
Clenproperol is a agonistβ2-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clenproperol-D7Cat No HY-100699S
Clenproperol-D7 is the deuterium labeledClenproperol Clenproperol is a β2-adrenergicagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ClonidineCat No HY-12721
Clonidine is an agonist which isalpha 2-adrenergicused extensively in anesthesia research
Purity 9879Clinical Data LaunchedSize 1 mg 5 mg
Clonidine hydrochlorideCat No HY-B0409A
Clonidine hydrochloride is an agonist of and potent antihypertensiveα2-adrenoceptor
agent
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Clorprenaline D7Cat No HY-131106S
Clorprenaline D7 is a deuterium labeledClorprenaline Clorprenaline is a β2-adrenergic
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clorprenaline hydrochlorideCat No HY-B1347
Clorprenaline hydrochloride is a β -adrenergic2
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
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D2343Cat No HY-U00206
D2343 is a agonist and also is anβ2-adrenoceptor inhibitorα1- adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Dabuzalgron (Ro 115-1240) Cat No HY-117071
Dabuzalgron (Ro 115-1240) is an orally active andselective agonist forα-1A adrenergic receptorthe treatment of urinary incontinence Dabuzalgronprotects against Doxorubicin-inducedcardiotoxicity by preserving mitochondrialfunction
Purity 9872Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Dapiprazole hydrochlorideCat No HY-A0142A
Dapiprazole hydrochloride is a potent α-adrenergicblocking drug which is used to reverse mydriasisafter eye examination
Purity 9997Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
Deriglidole (SL 86-0715) Cat No HY-101683
Deriglidole is a peripheral adrenoceptorantagonist with a high affinity forα -adrenoceptors2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DetomidineCat No HY-B0163
Detomidine produce dose-dependent sedative andanalgesic effects is a nonnarcotic syntheticα2-adrenergic agonist Target α2-adrenergicagonist Detomidine is an imidazole derivative andα2-adrenergic agonist used as a large animalsedative primarily used in horses
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Detomidine carboxylic acidCat No HY-135895
Detomidine carboxylic acid is the major urinarymetabolite of Detomidine Detomidine is asynthetic agonist and an animalα2-adrenergicanalgesic sedative Detomidine also has cardiacand respiratory effects and an antidiureticaction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Detomidine hydrochlorideCat No HY-B0163A
Detomidine hydrochloride produce dose-dependentsedative and analgesic effects is a nonnarcoticsynthetic α2-adrenergic agonist Targetα2-adrenergic agonist Detomidine is an imidazolederivative and α2-adrenergic agonist used as alarge animal sedative primarily used inhellip
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Dexmedetomidine hydrochloride ((+)-Medetomidine
hydrochloride (S)-Medetomidine hydrochloride) Cat No HY-17034A
Dexmedetomidine Hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9854Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg
Diacetolol D7Cat No HY-100635S
Diacetolol D7 is a deuterium labeled DiacetololDiacetolol is the major metabolite of AcebutololDiacetolol is a blocking andβ-adrenoceptoranti-arrhythmic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DicentrineCat No HY-N6969
Dicentrine is a natural product isolated from theplant with antihypertensiveLindera megaphyllaeffect Dicentrine is an α -adrenoceptor1
antagonist which has effective against humanhyperplastic prostates
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 9
DL-Epinephrine ((plusmn)-Epinephrine DL-Adrenaline (plusmn)-Adrenaline) Cat No HY-B0447
DL-Epinephrine is the racemate of epinephrineL-Epinephrine is a hormone secreted by the medullaof the adrenal glands L-Epinephrine is an
and receptor agonistα-adrenergic β-adrenergic
Purity gt990Clinical Data No Development ReportedSize 500 mg 1 g 5 g
DL-Norepinephrine hydrochlorideCat No HY-N7142
DL-Norepinephrine hydrochloride is a syntheticphenylethylamine that mimics the sympathomimeticactions of the endogenousnorepinephrineDL-Norepinephrine hydrochloride isa neurotransmitter targets α1 and β1
has an increasing effecthellipadrenoceptors
Purity 9953Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Dobutamine hydrochlorideCat No HY-15746
Dobutamine hydrochloride is a syntheticcatecholamine that acts on α1-AR β1-AR β2-AR
Dobutamine(α-1 β-1 andβ-2 adrenoceptors)hydrochloride is a selective β1-AR agonistrelatively weak activity at α1-AR and β2-AR
Purity 9947Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Dopexamine hydrochloride (FPL60278AR) Cat No HY-U00205
Dopexamine hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin (UK 33274) Cat No HY-B0098
Doxazosin (UK 33274) is a quinazoline-derivativethat selectively antagonizes postsynaptic
α1-adrenergic receptors
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin D8 (UK 33274 D8) Cat No HY-B0098S
Doxazosin D8 (UK 33274 D8) is a deuterium labeledDoxazosin (UK 33274) Doxazosin is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1 adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Doxazosin mesylate (UK 33274 mesylate) Cat No HY-B0098A
Doxazosin mesylate (UK 33274) is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1-adrenergic receptors
Purity 9860Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
EcastololCat No HY-101691
Ecastolol is a beta adrenergic receptorantagonist with antianginal activities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Epanolol (Visacor ICI141292) Cat No HY-U00183
Epanolol (Visacor ICI141292) is a potent partial agonist with a greaterβ-adrenoceptor
affinity for - than β2-adrenoceptorsβ1
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Esmolol hydrochlorideCat No HY-B1392
Esmolol hydrochloride is a beta adrenergicreceptor blocker
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
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Falintolol (Z)-Cat No HY-U00283
Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oximefunction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenmetozole TosylateCat No HY-U00402
Fenmetozole Tosylate is an antagonist of theactions of ethanol also antagonizes α2-adrenergic
and acts as an antidepressant drugreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenoterol (Th-1165 Phenoterol) Cat No HY-B0976
Fenoterol is a β 2 adrenergic agonist designed toopen up the airways to the lungs is classed assympathomimetic β2 agonist and asthma medication
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Fenoterol hydrobromide (Fenoterol bromide Th-1165a Phenoterol hydrobromide) Cat No HY-B0976A
Fenoterol hydrobromide is a β 2 adrenergic agonistdesigned to open up the airways to the lungs isclassed as sympathomimetic β2 agonist and asthmamedication
Purity 9971Clinical Data LaunchedSize 100 mg
Fenspiride HydrochlorideCat No HY-A0027
Fenspiride Hcl is an α adrenergic and H1 histaminereceptor antagonist IC50 value TargetAdrenergic receptor H1 receptor Fenspiridehydrochloride is a bronchodilator withanti-inflammatory properties
Purity 9903Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
FiduxosinCat No HY-U00399
Fiduxosin is a potent antagonistα1-adrenoceptorwith of 0160 nM 249 nM and 0920 nM forKi
α1a- α1b- and α1d-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg
Formoterol Fumarate (Formoterol) Cat No HY-B0010
Formoterol fumarate(Foradil) is a potentselective and long-acting β2-adrenoceptor agonist
Purity 9894Clinical Data LaunchedSize 10 mg 50 mg
G-Protein antagonist peptideCat No HY-P1376
G-Protein antagonist peptide is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
G-Protein antagonist peptide TFACat No HY-P1376A
G-Protein antagonist peptide TFA is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide TFA competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Glaucine (OO-Dimethylisoboldine S-(+)-Glaucine NSC 34396) Cat No HY-N3945
Glaucine (OO-Dimethylisoboldine) is an alkaloidisolated from Crantz withGlaucium flavumantitussive bronchodilation and anti-inflammatoryproperties
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 11
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
14 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
16 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
18 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
20 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
ACTH (1-14) (TFA) (Adrenocorticotropic Hormone Fragment 1-14 TFA) Cat No HY-P1582A
ACTH (1-14) (TFA) is a fragment ofadrenocorticotrophin which regulates cortisol andandrogen production
Purity 9855Clinical Data No Development ReportedSize 1 mg 5 mg 10 mg
ADRA1D receptor agonist 1Cat No HY-135270
ADRA1D receptor agonist 1 (compound (R)-9S) is apotent selective and orally active α1D
antagonist with a of 16 nMadrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
AGN 192836Cat No HY-100300
AGN 192836 is a potent and selective α2 adrenergicagonist with s of 87 41 and 66 nM forEC50
α2A α2B and α2C receptor respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ajmalicine (Raubasine) Cat No HY-N1919
Ajmalicine (Raubasine) is found in herbs ofCatharanthus roseus is an antihypertensive drugused in the treatment of high blood pressuredecreases peripheral resistance and bloodpressure
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Alfuzosin (SL 77499) Cat No HY-B0192
Alfuzosin is an α1 adrenergic receptor antagonistused to treat benign prostatic hyperplasia (BPH)
Purity 9981Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Alfuzosin hydrochloride (SL 77499-10) Cat No HY-B0192A
Alfuzosin hydrochloride is an α1 adrenergicreceptor antagonist used to treat benign prostatichyperplasia (BPH)
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Amezinium methylsulfate (Amezinium metilsulfate Lu-1631) Cat No HY-A0275
Amezinium metilsulfate has multiple mechanismsincluding stimulation of alpha and beta-1receptors and inhibition ofnoradrenaline andtyramine uptake
Purity 9951Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
Amibegron hydrochloride (SR 58611A) Cat No HY-103207
Amibegron hydrochloride is a selective agonist with an of 35 nMβ3-adrenoceptor EC50
for in rat colon Amibegronβ-adrenoceptorhydrochloride has anxiolytic and antidepressantactivity
Purity gt990Clinical Data No Development ReportedSize 5 mg
Amitraz (BTS-27419) Cat No HY-B1111
Amitraz is a non-systemic acaricide andinsecticide with alpha-adrenergic agonistactivity interaction with octopamine receptors ofthe central nervous system and inhibition ofmonoamine oxidases and prostaglandin synthesis
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
AncarololCat No HY-100141
Ancarolol is a blocking agentbeta-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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AR-08Cat No HY-U00371
AR-08 is an agonist of α2-adrenergic receptorused for the treatment of attention deficithyperactivety disorder (ADHD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ArbutamineCat No HY-16056
Arbutamine is a short-acting synthetic potentnonselective agonist thatβ-adrenoceptorincreases heart rate cardiac contractility andsystolic blood pressure Arbutamine is acatecholamine for a pharmacological cardiac stressagen
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
ArotinololCat No HY-122537A
Arotinolol is a nonselective αβ-adrenergic blocker and a vasodilating β-blockerreceptor
Arotinolol also shows potency for inhibiting thebinding of the radioligand I-ICYP to125
-serotonergic receptor sites5HT1B
Purity 9818Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Asenapine (Org 5222) Cat No HY-10121
Asenapine(Org 5222) inhibits adrenergic receptor(α1 α2A α2B α2C) with Ki of 025-12 nM andalso inhibits 5-HT receptor (1A 1B 2A 2B 2C5A 6 7) with Ki of 003-40 nM
Purity 9881Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Atenolol ((RS)-Atenolol) Cat No HY-17498
Atenolol is a selective β1 receptor antagonistTarget Adrenergic Receptor Atenolol is acardioselective beta-adrenergic blocker possessingproperties and potency similar to propranolol butwithout a negative inotropic effect [1 2]
Purity 9961Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Atipamezole (MPV 1248) Cat No HY-12380A
Atipamezole is a synthetic α -adrenoceptor2
with a of 16 nMantagonist Ki
Purity 9948Clinical Data Phase 1Size 10 mM times 1 mL 10 mg 50 mg
Atipamezole hydrochloride (MPV-1248 hydrochloride) Cat No HY-12380
Atipamezole hydrochloride is a synthetic with a of 16 nMα -adrenoceptor antagonist2 Ki
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Bambuterol ((plusmn)-Bambuterol KWD-2183) Cat No HY-17501
Bambuterol ((plusmn)-Bambuterol KWD-2183) is a longacting beta-adrenoceptor agonist (LABA) used inthe treatment of asthma it also is a prodrug ofterbutaline
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Bambuterol hydrochloride ((plusmn)-Bambuterol hydrochloride KWD-2183 hydrochloride) Cat No HY-17501A
Bambuterol hydrochloride ((plusmn)-Bambuterolhydrochloride KWD-2183 hydrochloride) is a longacting beta-adrenoceptor agonist (LABA) used inthe treatment of asthma it also is a prodrug ofterbutaline
Purity 9957Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Batefenterol (GSK961081 TD-5959) Cat No HY-12980
Batefenterol (GSK961081TD-5959) is a novel receptor antagonist andmuscarinic
agonist displays high affinityβ -adrenoceptor2
for hM2 hM3 muscarinic and hβ -adrenoceptor with2
values of 14 13 and 37 nM respectivelyKi
Purity 9817Clinical Data Phase 2Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 5
Benzquinamide (P2647 BZQ Benzoquinamide) Cat No HY-U00244
Benzquinamide (P2647) is an antiemetic which canbind to the and α2A α2B α2C adrenergic
(α2-AR) with K values of 1365 691receptors i
and 545 nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BetaxololCat No HY-B0381
Betaxolol is a selective beta1 adrenergic receptorblocker used in the treatment of hypertension andglaucoma Target Beta1 Adrenergic ReceptorBetaxolol is a cardioselective beta-adrenergicreceptor blocking agent Betaxolol (5 mgkg viaip
Purity 9695Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Betaxolol hydrochloride (SL75212) Cat No HY-B0381A
Betaxolol Hydrochloride is a selective beta1adrenergic receptor blocker used in the treatmentof hypertension and glaucoma Target Beta1Adrenergic Receptor Betaxolol hydrochloride is acardioselective beta-adrenergic receptor blockingagent
Purity 9894Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Bevantolol hydrochlorideCat No HY-121186
Bevantolol hydrochloride is a selective andβ1α1-adrenergic receptor antagonist with valuespKi
of 783 69 in rat cerebral cortex respectivelyBevantolol hydrochloride is a potent Ca2+
antagonist
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 25 mg 50 mg 100 mg
BI-167107Cat No HY-121251
BI-167107 is a high affinity full agonist thatbinds to the β2 adrenergic receptor ( ) with aβ2ARdissociation constant of 84 pMKd
Purity 9981Clinical DataSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Bometolol HydrochlorideCat No HY-U00386
Bometolol Hydrochloride is a beta-adrenergicblocking agent used for the research ofcardiovascular disease
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brimonidine (UK 14304 AGN190342) Cat No HY-B0659
Brimonidine (UK 14304) is a full α2-adrenergicreceptor (α2-AR) agonist
Purity 9965Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Brimonidine tartrate (UK 14304 tartrate AGN190342 tartrate) Cat No HY-B0659A
Brimonidine tartrate (UK 14304 tartrate) is a fullα2-adrenergic receptor (α2-AR) agonist
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
BRL 37344 sodium (BRL 37344A) Cat No HY-101325
BRL 37344 sodium (BRL 37344A) is a specific agonist BRL 37344 sodiumβ3-adrenergic receptor
treatment significantly lowers the body weight ofobese mice
Purity gt990Clinical Data No Development ReportedSize 1 mg
Brombuterol D9 (Bromobuterol D9) Cat No HY-131104S
Brombuterol D9 (Bromobuterol D9) is a deuteriumlabeled Brombuterol Brombuterol is a β-adrenergic
agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
6 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Brombuterol D9 hydrochloride (Bromobuterol D9 hydrochloride) Cat No HY-131104AS
Brombuterol D9 hydrochloride (Bromobuterol D9hydrochloride) is a deuterium labeled Brombuterolhydrochloride Brombuterol hydrochloride is a
agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brombuterol hydrochloride (Bromobuterol hydrochloride) Cat No HY-131145
Brombuterol hydrochloride (Bromobuterolhydrochloride) is a agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BucindololCat No HY-103214
Bucindolol is a blockerβ1-adrenergic receptorwith intrinsic sympathomimetic activity used inthe research of heart failure
Purity gt990Clinical Data No Development ReportedSize 1 mg 5 mg
Carbazochrome sodium sulfonate (AC-17) Cat No HY-B0491A
Carbazochrome (sodium sulfonate) (AC-17) is anantihemorrhagic agent
Purity 9951Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carteolol hydrochloride (OPC-1085 hydrochloride) Cat No HY-17495A
Carteolol hydrochloride (OPC-1085 hydrochloride)is a non-selective beta blocker used to treatglaucoma
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carvedilol (BM 14190) Cat No HY-B0006
Carvedilol (BM 14190) is a non-selective βα-1blocker Carvedilol inhibits lipid peroxidation ina dose-dependent manner with an IC of 5 μM50
Carvedilol is a multiple action antihypertensiveagent with potential use in angina and congestiveheart failure
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) Cat No HY-B0006A
Carvedilol phosphate hemihydrate (BM 14190phosphate hemihydrate) is a non-selective βα-1blocker Carvedilol phosphate hemihydrate inhibits
with an IC of 5 μMlipid peroxidation 50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Centanafadine (EB-1020) Cat No HY-16736
Centanafadine is dual norepinephrine (NE)dopamine transporter inhibitor also inhibits(DA)
serotonin transporter with of 6 nM 38 nMIC s50
and 83 nM for human NE DA and serotonintransporter respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Centanafadine hydrochloride (EB-1020 hydrochloride) Cat No HY-16736A
Centanafadine (hydrochloride) is dual transporternorepinephrine (NE)dopamine (DA)
inhibitor also inhibits serotonin transporterwith of 6 nM 38 nM and 83 nM for human NEIC s50
DA and serotonin transporter respectively
Purity 9993Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
CGP 20712 A (CGP 20712 mesylate) Cat No HY-101355B
CGP 20712 A (CGP 20712 mesylate) is a highlyselective ltBgtβ1-adrenoceptorltBgtantagonist with an of 07 nM CGP 20712 AIC50
exhibits ~10000-fold selectivity overβ2-adrenoceptors
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
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Cicloprolol hydrochlorideCat No HY-U00066
Cicloprolol is a partial β 1-adrenoceptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimaterol-D7Cat No HY-100935S
Cimaterol-D7 is the deuterium labeled CimaterolCimaterol is a potent agonist of β-adrenergicreceptors (pEC s=813 878 and 662 for human50
β1 β2 and β3 respectively) Cimaterol has beenused in farmed animals to increase carcass massand to alter muscle and fat deposition
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimbuterol-D9Cat No HY-131105S
Cimbuterol-D9 is the deuterium labeled CimbuterolCimbuterol is aβ-adrenergic agonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
CL 316243Cat No HY-116771A
CL316243 is a highly potent selective agonist with a of 3 nMβ3-adrenoceptor EC50
but is an extremely poor toβ12- receptors
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg
ClenproperolCat No HY-100699
Clenproperol is a agonistβ2-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clenproperol-D7Cat No HY-100699S
Clenproperol-D7 is the deuterium labeledClenproperol Clenproperol is a β2-adrenergicagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ClonidineCat No HY-12721
Clonidine is an agonist which isalpha 2-adrenergicused extensively in anesthesia research
Purity 9879Clinical Data LaunchedSize 1 mg 5 mg
Clonidine hydrochlorideCat No HY-B0409A
Clonidine hydrochloride is an agonist of and potent antihypertensiveα2-adrenoceptor
agent
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Clorprenaline D7Cat No HY-131106S
Clorprenaline D7 is a deuterium labeledClorprenaline Clorprenaline is a β2-adrenergic
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clorprenaline hydrochlorideCat No HY-B1347
Clorprenaline hydrochloride is a β -adrenergic2
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
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D2343Cat No HY-U00206
D2343 is a agonist and also is anβ2-adrenoceptor inhibitorα1- adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Dabuzalgron (Ro 115-1240) Cat No HY-117071
Dabuzalgron (Ro 115-1240) is an orally active andselective agonist forα-1A adrenergic receptorthe treatment of urinary incontinence Dabuzalgronprotects against Doxorubicin-inducedcardiotoxicity by preserving mitochondrialfunction
Purity 9872Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Dapiprazole hydrochlorideCat No HY-A0142A
Dapiprazole hydrochloride is a potent α-adrenergicblocking drug which is used to reverse mydriasisafter eye examination
Purity 9997Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
Deriglidole (SL 86-0715) Cat No HY-101683
Deriglidole is a peripheral adrenoceptorantagonist with a high affinity forα -adrenoceptors2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DetomidineCat No HY-B0163
Detomidine produce dose-dependent sedative andanalgesic effects is a nonnarcotic syntheticα2-adrenergic agonist Target α2-adrenergicagonist Detomidine is an imidazole derivative andα2-adrenergic agonist used as a large animalsedative primarily used in horses
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Detomidine carboxylic acidCat No HY-135895
Detomidine carboxylic acid is the major urinarymetabolite of Detomidine Detomidine is asynthetic agonist and an animalα2-adrenergicanalgesic sedative Detomidine also has cardiacand respiratory effects and an antidiureticaction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Detomidine hydrochlorideCat No HY-B0163A
Detomidine hydrochloride produce dose-dependentsedative and analgesic effects is a nonnarcoticsynthetic α2-adrenergic agonist Targetα2-adrenergic agonist Detomidine is an imidazolederivative and α2-adrenergic agonist used as alarge animal sedative primarily used inhellip
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Dexmedetomidine hydrochloride ((+)-Medetomidine
hydrochloride (S)-Medetomidine hydrochloride) Cat No HY-17034A
Dexmedetomidine Hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9854Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg
Diacetolol D7Cat No HY-100635S
Diacetolol D7 is a deuterium labeled DiacetololDiacetolol is the major metabolite of AcebutololDiacetolol is a blocking andβ-adrenoceptoranti-arrhythmic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DicentrineCat No HY-N6969
Dicentrine is a natural product isolated from theplant with antihypertensiveLindera megaphyllaeffect Dicentrine is an α -adrenoceptor1
antagonist which has effective against humanhyperplastic prostates
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 9
DL-Epinephrine ((plusmn)-Epinephrine DL-Adrenaline (plusmn)-Adrenaline) Cat No HY-B0447
DL-Epinephrine is the racemate of epinephrineL-Epinephrine is a hormone secreted by the medullaof the adrenal glands L-Epinephrine is an
and receptor agonistα-adrenergic β-adrenergic
Purity gt990Clinical Data No Development ReportedSize 500 mg 1 g 5 g
DL-Norepinephrine hydrochlorideCat No HY-N7142
DL-Norepinephrine hydrochloride is a syntheticphenylethylamine that mimics the sympathomimeticactions of the endogenousnorepinephrineDL-Norepinephrine hydrochloride isa neurotransmitter targets α1 and β1
has an increasing effecthellipadrenoceptors
Purity 9953Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Dobutamine hydrochlorideCat No HY-15746
Dobutamine hydrochloride is a syntheticcatecholamine that acts on α1-AR β1-AR β2-AR
Dobutamine(α-1 β-1 andβ-2 adrenoceptors)hydrochloride is a selective β1-AR agonistrelatively weak activity at α1-AR and β2-AR
Purity 9947Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Dopexamine hydrochloride (FPL60278AR) Cat No HY-U00205
Dopexamine hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin (UK 33274) Cat No HY-B0098
Doxazosin (UK 33274) is a quinazoline-derivativethat selectively antagonizes postsynaptic
α1-adrenergic receptors
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin D8 (UK 33274 D8) Cat No HY-B0098S
Doxazosin D8 (UK 33274 D8) is a deuterium labeledDoxazosin (UK 33274) Doxazosin is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1 adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Doxazosin mesylate (UK 33274 mesylate) Cat No HY-B0098A
Doxazosin mesylate (UK 33274) is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1-adrenergic receptors
Purity 9860Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
EcastololCat No HY-101691
Ecastolol is a beta adrenergic receptorantagonist with antianginal activities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Epanolol (Visacor ICI141292) Cat No HY-U00183
Epanolol (Visacor ICI141292) is a potent partial agonist with a greaterβ-adrenoceptor
affinity for - than β2-adrenoceptorsβ1
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Esmolol hydrochlorideCat No HY-B1392
Esmolol hydrochloride is a beta adrenergicreceptor blocker
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
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Falintolol (Z)-Cat No HY-U00283
Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oximefunction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenmetozole TosylateCat No HY-U00402
Fenmetozole Tosylate is an antagonist of theactions of ethanol also antagonizes α2-adrenergic
and acts as an antidepressant drugreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenoterol (Th-1165 Phenoterol) Cat No HY-B0976
Fenoterol is a β 2 adrenergic agonist designed toopen up the airways to the lungs is classed assympathomimetic β2 agonist and asthma medication
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Fenoterol hydrobromide (Fenoterol bromide Th-1165a Phenoterol hydrobromide) Cat No HY-B0976A
Fenoterol hydrobromide is a β 2 adrenergic agonistdesigned to open up the airways to the lungs isclassed as sympathomimetic β2 agonist and asthmamedication
Purity 9971Clinical Data LaunchedSize 100 mg
Fenspiride HydrochlorideCat No HY-A0027
Fenspiride Hcl is an α adrenergic and H1 histaminereceptor antagonist IC50 value TargetAdrenergic receptor H1 receptor Fenspiridehydrochloride is a bronchodilator withanti-inflammatory properties
Purity 9903Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
FiduxosinCat No HY-U00399
Fiduxosin is a potent antagonistα1-adrenoceptorwith of 0160 nM 249 nM and 0920 nM forKi
α1a- α1b- and α1d-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg
Formoterol Fumarate (Formoterol) Cat No HY-B0010
Formoterol fumarate(Foradil) is a potentselective and long-acting β2-adrenoceptor agonist
Purity 9894Clinical Data LaunchedSize 10 mg 50 mg
G-Protein antagonist peptideCat No HY-P1376
G-Protein antagonist peptide is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
G-Protein antagonist peptide TFACat No HY-P1376A
G-Protein antagonist peptide TFA is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide TFA competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Glaucine (OO-Dimethylisoboldine S-(+)-Glaucine NSC 34396) Cat No HY-N3945
Glaucine (OO-Dimethylisoboldine) is an alkaloidisolated from Crantz withGlaucium flavumantitussive bronchodilation and anti-inflammatoryproperties
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 11
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
14 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
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Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
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NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
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RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
AR-08Cat No HY-U00371
AR-08 is an agonist of α2-adrenergic receptorused for the treatment of attention deficithyperactivety disorder (ADHD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ArbutamineCat No HY-16056
Arbutamine is a short-acting synthetic potentnonselective agonist thatβ-adrenoceptorincreases heart rate cardiac contractility andsystolic blood pressure Arbutamine is acatecholamine for a pharmacological cardiac stressagen
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
ArotinololCat No HY-122537A
Arotinolol is a nonselective αβ-adrenergic blocker and a vasodilating β-blockerreceptor
Arotinolol also shows potency for inhibiting thebinding of the radioligand I-ICYP to125
-serotonergic receptor sites5HT1B
Purity 9818Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Asenapine (Org 5222) Cat No HY-10121
Asenapine(Org 5222) inhibits adrenergic receptor(α1 α2A α2B α2C) with Ki of 025-12 nM andalso inhibits 5-HT receptor (1A 1B 2A 2B 2C5A 6 7) with Ki of 003-40 nM
Purity 9881Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Atenolol ((RS)-Atenolol) Cat No HY-17498
Atenolol is a selective β1 receptor antagonistTarget Adrenergic Receptor Atenolol is acardioselective beta-adrenergic blocker possessingproperties and potency similar to propranolol butwithout a negative inotropic effect [1 2]
Purity 9961Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Atipamezole (MPV 1248) Cat No HY-12380A
Atipamezole is a synthetic α -adrenoceptor2
with a of 16 nMantagonist Ki
Purity 9948Clinical Data Phase 1Size 10 mM times 1 mL 10 mg 50 mg
Atipamezole hydrochloride (MPV-1248 hydrochloride) Cat No HY-12380
Atipamezole hydrochloride is a synthetic with a of 16 nMα -adrenoceptor antagonist2 Ki
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Bambuterol ((plusmn)-Bambuterol KWD-2183) Cat No HY-17501
Bambuterol ((plusmn)-Bambuterol KWD-2183) is a longacting beta-adrenoceptor agonist (LABA) used inthe treatment of asthma it also is a prodrug ofterbutaline
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Bambuterol hydrochloride ((plusmn)-Bambuterol hydrochloride KWD-2183 hydrochloride) Cat No HY-17501A
Bambuterol hydrochloride ((plusmn)-Bambuterolhydrochloride KWD-2183 hydrochloride) is a longacting beta-adrenoceptor agonist (LABA) used inthe treatment of asthma it also is a prodrug ofterbutaline
Purity 9957Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Batefenterol (GSK961081 TD-5959) Cat No HY-12980
Batefenterol (GSK961081TD-5959) is a novel receptor antagonist andmuscarinic
agonist displays high affinityβ -adrenoceptor2
for hM2 hM3 muscarinic and hβ -adrenoceptor with2
values of 14 13 and 37 nM respectivelyKi
Purity 9817Clinical Data Phase 2Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 5
Benzquinamide (P2647 BZQ Benzoquinamide) Cat No HY-U00244
Benzquinamide (P2647) is an antiemetic which canbind to the and α2A α2B α2C adrenergic
(α2-AR) with K values of 1365 691receptors i
and 545 nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BetaxololCat No HY-B0381
Betaxolol is a selective beta1 adrenergic receptorblocker used in the treatment of hypertension andglaucoma Target Beta1 Adrenergic ReceptorBetaxolol is a cardioselective beta-adrenergicreceptor blocking agent Betaxolol (5 mgkg viaip
Purity 9695Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Betaxolol hydrochloride (SL75212) Cat No HY-B0381A
Betaxolol Hydrochloride is a selective beta1adrenergic receptor blocker used in the treatmentof hypertension and glaucoma Target Beta1Adrenergic Receptor Betaxolol hydrochloride is acardioselective beta-adrenergic receptor blockingagent
Purity 9894Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Bevantolol hydrochlorideCat No HY-121186
Bevantolol hydrochloride is a selective andβ1α1-adrenergic receptor antagonist with valuespKi
of 783 69 in rat cerebral cortex respectivelyBevantolol hydrochloride is a potent Ca2+
antagonist
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 25 mg 50 mg 100 mg
BI-167107Cat No HY-121251
BI-167107 is a high affinity full agonist thatbinds to the β2 adrenergic receptor ( ) with aβ2ARdissociation constant of 84 pMKd
Purity 9981Clinical DataSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Bometolol HydrochlorideCat No HY-U00386
Bometolol Hydrochloride is a beta-adrenergicblocking agent used for the research ofcardiovascular disease
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brimonidine (UK 14304 AGN190342) Cat No HY-B0659
Brimonidine (UK 14304) is a full α2-adrenergicreceptor (α2-AR) agonist
Purity 9965Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Brimonidine tartrate (UK 14304 tartrate AGN190342 tartrate) Cat No HY-B0659A
Brimonidine tartrate (UK 14304 tartrate) is a fullα2-adrenergic receptor (α2-AR) agonist
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
BRL 37344 sodium (BRL 37344A) Cat No HY-101325
BRL 37344 sodium (BRL 37344A) is a specific agonist BRL 37344 sodiumβ3-adrenergic receptor
treatment significantly lowers the body weight ofobese mice
Purity gt990Clinical Data No Development ReportedSize 1 mg
Brombuterol D9 (Bromobuterol D9) Cat No HY-131104S
Brombuterol D9 (Bromobuterol D9) is a deuteriumlabeled Brombuterol Brombuterol is a β-adrenergic
agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Brombuterol D9 hydrochloride (Bromobuterol D9 hydrochloride) Cat No HY-131104AS
Brombuterol D9 hydrochloride (Bromobuterol D9hydrochloride) is a deuterium labeled Brombuterolhydrochloride Brombuterol hydrochloride is a
agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brombuterol hydrochloride (Bromobuterol hydrochloride) Cat No HY-131145
Brombuterol hydrochloride (Bromobuterolhydrochloride) is a agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BucindololCat No HY-103214
Bucindolol is a blockerβ1-adrenergic receptorwith intrinsic sympathomimetic activity used inthe research of heart failure
Purity gt990Clinical Data No Development ReportedSize 1 mg 5 mg
Carbazochrome sodium sulfonate (AC-17) Cat No HY-B0491A
Carbazochrome (sodium sulfonate) (AC-17) is anantihemorrhagic agent
Purity 9951Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carteolol hydrochloride (OPC-1085 hydrochloride) Cat No HY-17495A
Carteolol hydrochloride (OPC-1085 hydrochloride)is a non-selective beta blocker used to treatglaucoma
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carvedilol (BM 14190) Cat No HY-B0006
Carvedilol (BM 14190) is a non-selective βα-1blocker Carvedilol inhibits lipid peroxidation ina dose-dependent manner with an IC of 5 μM50
Carvedilol is a multiple action antihypertensiveagent with potential use in angina and congestiveheart failure
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) Cat No HY-B0006A
Carvedilol phosphate hemihydrate (BM 14190phosphate hemihydrate) is a non-selective βα-1blocker Carvedilol phosphate hemihydrate inhibits
with an IC of 5 μMlipid peroxidation 50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Centanafadine (EB-1020) Cat No HY-16736
Centanafadine is dual norepinephrine (NE)dopamine transporter inhibitor also inhibits(DA)
serotonin transporter with of 6 nM 38 nMIC s50
and 83 nM for human NE DA and serotonintransporter respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Centanafadine hydrochloride (EB-1020 hydrochloride) Cat No HY-16736A
Centanafadine (hydrochloride) is dual transporternorepinephrine (NE)dopamine (DA)
inhibitor also inhibits serotonin transporterwith of 6 nM 38 nM and 83 nM for human NEIC s50
DA and serotonin transporter respectively
Purity 9993Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
CGP 20712 A (CGP 20712 mesylate) Cat No HY-101355B
CGP 20712 A (CGP 20712 mesylate) is a highlyselective ltBgtβ1-adrenoceptorltBgtantagonist with an of 07 nM CGP 20712 AIC50
exhibits ~10000-fold selectivity overβ2-adrenoceptors
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
wwwMedChemExpresscom 7
Cicloprolol hydrochlorideCat No HY-U00066
Cicloprolol is a partial β 1-adrenoceptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimaterol-D7Cat No HY-100935S
Cimaterol-D7 is the deuterium labeled CimaterolCimaterol is a potent agonist of β-adrenergicreceptors (pEC s=813 878 and 662 for human50
β1 β2 and β3 respectively) Cimaterol has beenused in farmed animals to increase carcass massand to alter muscle and fat deposition
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimbuterol-D9Cat No HY-131105S
Cimbuterol-D9 is the deuterium labeled CimbuterolCimbuterol is aβ-adrenergic agonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
CL 316243Cat No HY-116771A
CL316243 is a highly potent selective agonist with a of 3 nMβ3-adrenoceptor EC50
but is an extremely poor toβ12- receptors
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg
ClenproperolCat No HY-100699
Clenproperol is a agonistβ2-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clenproperol-D7Cat No HY-100699S
Clenproperol-D7 is the deuterium labeledClenproperol Clenproperol is a β2-adrenergicagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ClonidineCat No HY-12721
Clonidine is an agonist which isalpha 2-adrenergicused extensively in anesthesia research
Purity 9879Clinical Data LaunchedSize 1 mg 5 mg
Clonidine hydrochlorideCat No HY-B0409A
Clonidine hydrochloride is an agonist of and potent antihypertensiveα2-adrenoceptor
agent
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Clorprenaline D7Cat No HY-131106S
Clorprenaline D7 is a deuterium labeledClorprenaline Clorprenaline is a β2-adrenergic
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clorprenaline hydrochlorideCat No HY-B1347
Clorprenaline hydrochloride is a β -adrenergic2
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
8 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
D2343Cat No HY-U00206
D2343 is a agonist and also is anβ2-adrenoceptor inhibitorα1- adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Dabuzalgron (Ro 115-1240) Cat No HY-117071
Dabuzalgron (Ro 115-1240) is an orally active andselective agonist forα-1A adrenergic receptorthe treatment of urinary incontinence Dabuzalgronprotects against Doxorubicin-inducedcardiotoxicity by preserving mitochondrialfunction
Purity 9872Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Dapiprazole hydrochlorideCat No HY-A0142A
Dapiprazole hydrochloride is a potent α-adrenergicblocking drug which is used to reverse mydriasisafter eye examination
Purity 9997Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
Deriglidole (SL 86-0715) Cat No HY-101683
Deriglidole is a peripheral adrenoceptorantagonist with a high affinity forα -adrenoceptors2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DetomidineCat No HY-B0163
Detomidine produce dose-dependent sedative andanalgesic effects is a nonnarcotic syntheticα2-adrenergic agonist Target α2-adrenergicagonist Detomidine is an imidazole derivative andα2-adrenergic agonist used as a large animalsedative primarily used in horses
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Detomidine carboxylic acidCat No HY-135895
Detomidine carboxylic acid is the major urinarymetabolite of Detomidine Detomidine is asynthetic agonist and an animalα2-adrenergicanalgesic sedative Detomidine also has cardiacand respiratory effects and an antidiureticaction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Detomidine hydrochlorideCat No HY-B0163A
Detomidine hydrochloride produce dose-dependentsedative and analgesic effects is a nonnarcoticsynthetic α2-adrenergic agonist Targetα2-adrenergic agonist Detomidine is an imidazolederivative and α2-adrenergic agonist used as alarge animal sedative primarily used inhellip
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Dexmedetomidine hydrochloride ((+)-Medetomidine
hydrochloride (S)-Medetomidine hydrochloride) Cat No HY-17034A
Dexmedetomidine Hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9854Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg
Diacetolol D7Cat No HY-100635S
Diacetolol D7 is a deuterium labeled DiacetololDiacetolol is the major metabolite of AcebutololDiacetolol is a blocking andβ-adrenoceptoranti-arrhythmic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DicentrineCat No HY-N6969
Dicentrine is a natural product isolated from theplant with antihypertensiveLindera megaphyllaeffect Dicentrine is an α -adrenoceptor1
antagonist which has effective against humanhyperplastic prostates
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 9
DL-Epinephrine ((plusmn)-Epinephrine DL-Adrenaline (plusmn)-Adrenaline) Cat No HY-B0447
DL-Epinephrine is the racemate of epinephrineL-Epinephrine is a hormone secreted by the medullaof the adrenal glands L-Epinephrine is an
and receptor agonistα-adrenergic β-adrenergic
Purity gt990Clinical Data No Development ReportedSize 500 mg 1 g 5 g
DL-Norepinephrine hydrochlorideCat No HY-N7142
DL-Norepinephrine hydrochloride is a syntheticphenylethylamine that mimics the sympathomimeticactions of the endogenousnorepinephrineDL-Norepinephrine hydrochloride isa neurotransmitter targets α1 and β1
has an increasing effecthellipadrenoceptors
Purity 9953Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Dobutamine hydrochlorideCat No HY-15746
Dobutamine hydrochloride is a syntheticcatecholamine that acts on α1-AR β1-AR β2-AR
Dobutamine(α-1 β-1 andβ-2 adrenoceptors)hydrochloride is a selective β1-AR agonistrelatively weak activity at α1-AR and β2-AR
Purity 9947Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Dopexamine hydrochloride (FPL60278AR) Cat No HY-U00205
Dopexamine hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin (UK 33274) Cat No HY-B0098
Doxazosin (UK 33274) is a quinazoline-derivativethat selectively antagonizes postsynaptic
α1-adrenergic receptors
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin D8 (UK 33274 D8) Cat No HY-B0098S
Doxazosin D8 (UK 33274 D8) is a deuterium labeledDoxazosin (UK 33274) Doxazosin is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1 adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Doxazosin mesylate (UK 33274 mesylate) Cat No HY-B0098A
Doxazosin mesylate (UK 33274) is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1-adrenergic receptors
Purity 9860Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
EcastololCat No HY-101691
Ecastolol is a beta adrenergic receptorantagonist with antianginal activities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Epanolol (Visacor ICI141292) Cat No HY-U00183
Epanolol (Visacor ICI141292) is a potent partial agonist with a greaterβ-adrenoceptor
affinity for - than β2-adrenoceptorsβ1
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Esmolol hydrochlorideCat No HY-B1392
Esmolol hydrochloride is a beta adrenergicreceptor blocker
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
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Falintolol (Z)-Cat No HY-U00283
Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oximefunction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenmetozole TosylateCat No HY-U00402
Fenmetozole Tosylate is an antagonist of theactions of ethanol also antagonizes α2-adrenergic
and acts as an antidepressant drugreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenoterol (Th-1165 Phenoterol) Cat No HY-B0976
Fenoterol is a β 2 adrenergic agonist designed toopen up the airways to the lungs is classed assympathomimetic β2 agonist and asthma medication
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Fenoterol hydrobromide (Fenoterol bromide Th-1165a Phenoterol hydrobromide) Cat No HY-B0976A
Fenoterol hydrobromide is a β 2 adrenergic agonistdesigned to open up the airways to the lungs isclassed as sympathomimetic β2 agonist and asthmamedication
Purity 9971Clinical Data LaunchedSize 100 mg
Fenspiride HydrochlorideCat No HY-A0027
Fenspiride Hcl is an α adrenergic and H1 histaminereceptor antagonist IC50 value TargetAdrenergic receptor H1 receptor Fenspiridehydrochloride is a bronchodilator withanti-inflammatory properties
Purity 9903Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
FiduxosinCat No HY-U00399
Fiduxosin is a potent antagonistα1-adrenoceptorwith of 0160 nM 249 nM and 0920 nM forKi
α1a- α1b- and α1d-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg
Formoterol Fumarate (Formoterol) Cat No HY-B0010
Formoterol fumarate(Foradil) is a potentselective and long-acting β2-adrenoceptor agonist
Purity 9894Clinical Data LaunchedSize 10 mg 50 mg
G-Protein antagonist peptideCat No HY-P1376
G-Protein antagonist peptide is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
G-Protein antagonist peptide TFACat No HY-P1376A
G-Protein antagonist peptide TFA is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide TFA competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Glaucine (OO-Dimethylisoboldine S-(+)-Glaucine NSC 34396) Cat No HY-N3945
Glaucine (OO-Dimethylisoboldine) is an alkaloidisolated from Crantz withGlaucium flavumantitussive bronchodilation and anti-inflammatoryproperties
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 11
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
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Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
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NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
20 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Benzquinamide (P2647 BZQ Benzoquinamide) Cat No HY-U00244
Benzquinamide (P2647) is an antiemetic which canbind to the and α2A α2B α2C adrenergic
(α2-AR) with K values of 1365 691receptors i
and 545 nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BetaxololCat No HY-B0381
Betaxolol is a selective beta1 adrenergic receptorblocker used in the treatment of hypertension andglaucoma Target Beta1 Adrenergic ReceptorBetaxolol is a cardioselective beta-adrenergicreceptor blocking agent Betaxolol (5 mgkg viaip
Purity 9695Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Betaxolol hydrochloride (SL75212) Cat No HY-B0381A
Betaxolol Hydrochloride is a selective beta1adrenergic receptor blocker used in the treatmentof hypertension and glaucoma Target Beta1Adrenergic Receptor Betaxolol hydrochloride is acardioselective beta-adrenergic receptor blockingagent
Purity 9894Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Bevantolol hydrochlorideCat No HY-121186
Bevantolol hydrochloride is a selective andβ1α1-adrenergic receptor antagonist with valuespKi
of 783 69 in rat cerebral cortex respectivelyBevantolol hydrochloride is a potent Ca2+
antagonist
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 25 mg 50 mg 100 mg
BI-167107Cat No HY-121251
BI-167107 is a high affinity full agonist thatbinds to the β2 adrenergic receptor ( ) with aβ2ARdissociation constant of 84 pMKd
Purity 9981Clinical DataSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Bometolol HydrochlorideCat No HY-U00386
Bometolol Hydrochloride is a beta-adrenergicblocking agent used for the research ofcardiovascular disease
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brimonidine (UK 14304 AGN190342) Cat No HY-B0659
Brimonidine (UK 14304) is a full α2-adrenergicreceptor (α2-AR) agonist
Purity 9965Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Brimonidine tartrate (UK 14304 tartrate AGN190342 tartrate) Cat No HY-B0659A
Brimonidine tartrate (UK 14304 tartrate) is a fullα2-adrenergic receptor (α2-AR) agonist
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
BRL 37344 sodium (BRL 37344A) Cat No HY-101325
BRL 37344 sodium (BRL 37344A) is a specific agonist BRL 37344 sodiumβ3-adrenergic receptor
treatment significantly lowers the body weight ofobese mice
Purity gt990Clinical Data No Development ReportedSize 1 mg
Brombuterol D9 (Bromobuterol D9) Cat No HY-131104S
Brombuterol D9 (Bromobuterol D9) is a deuteriumlabeled Brombuterol Brombuterol is a β-adrenergic
agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
6 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Brombuterol D9 hydrochloride (Bromobuterol D9 hydrochloride) Cat No HY-131104AS
Brombuterol D9 hydrochloride (Bromobuterol D9hydrochloride) is a deuterium labeled Brombuterolhydrochloride Brombuterol hydrochloride is a
agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brombuterol hydrochloride (Bromobuterol hydrochloride) Cat No HY-131145
Brombuterol hydrochloride (Bromobuterolhydrochloride) is a agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BucindololCat No HY-103214
Bucindolol is a blockerβ1-adrenergic receptorwith intrinsic sympathomimetic activity used inthe research of heart failure
Purity gt990Clinical Data No Development ReportedSize 1 mg 5 mg
Carbazochrome sodium sulfonate (AC-17) Cat No HY-B0491A
Carbazochrome (sodium sulfonate) (AC-17) is anantihemorrhagic agent
Purity 9951Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carteolol hydrochloride (OPC-1085 hydrochloride) Cat No HY-17495A
Carteolol hydrochloride (OPC-1085 hydrochloride)is a non-selective beta blocker used to treatglaucoma
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carvedilol (BM 14190) Cat No HY-B0006
Carvedilol (BM 14190) is a non-selective βα-1blocker Carvedilol inhibits lipid peroxidation ina dose-dependent manner with an IC of 5 μM50
Carvedilol is a multiple action antihypertensiveagent with potential use in angina and congestiveheart failure
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) Cat No HY-B0006A
Carvedilol phosphate hemihydrate (BM 14190phosphate hemihydrate) is a non-selective βα-1blocker Carvedilol phosphate hemihydrate inhibits
with an IC of 5 μMlipid peroxidation 50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Centanafadine (EB-1020) Cat No HY-16736
Centanafadine is dual norepinephrine (NE)dopamine transporter inhibitor also inhibits(DA)
serotonin transporter with of 6 nM 38 nMIC s50
and 83 nM for human NE DA and serotonintransporter respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Centanafadine hydrochloride (EB-1020 hydrochloride) Cat No HY-16736A
Centanafadine (hydrochloride) is dual transporternorepinephrine (NE)dopamine (DA)
inhibitor also inhibits serotonin transporterwith of 6 nM 38 nM and 83 nM for human NEIC s50
DA and serotonin transporter respectively
Purity 9993Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
CGP 20712 A (CGP 20712 mesylate) Cat No HY-101355B
CGP 20712 A (CGP 20712 mesylate) is a highlyselective ltBgtβ1-adrenoceptorltBgtantagonist with an of 07 nM CGP 20712 AIC50
exhibits ~10000-fold selectivity overβ2-adrenoceptors
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
wwwMedChemExpresscom 7
Cicloprolol hydrochlorideCat No HY-U00066
Cicloprolol is a partial β 1-adrenoceptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimaterol-D7Cat No HY-100935S
Cimaterol-D7 is the deuterium labeled CimaterolCimaterol is a potent agonist of β-adrenergicreceptors (pEC s=813 878 and 662 for human50
β1 β2 and β3 respectively) Cimaterol has beenused in farmed animals to increase carcass massand to alter muscle and fat deposition
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimbuterol-D9Cat No HY-131105S
Cimbuterol-D9 is the deuterium labeled CimbuterolCimbuterol is aβ-adrenergic agonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
CL 316243Cat No HY-116771A
CL316243 is a highly potent selective agonist with a of 3 nMβ3-adrenoceptor EC50
but is an extremely poor toβ12- receptors
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg
ClenproperolCat No HY-100699
Clenproperol is a agonistβ2-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clenproperol-D7Cat No HY-100699S
Clenproperol-D7 is the deuterium labeledClenproperol Clenproperol is a β2-adrenergicagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ClonidineCat No HY-12721
Clonidine is an agonist which isalpha 2-adrenergicused extensively in anesthesia research
Purity 9879Clinical Data LaunchedSize 1 mg 5 mg
Clonidine hydrochlorideCat No HY-B0409A
Clonidine hydrochloride is an agonist of and potent antihypertensiveα2-adrenoceptor
agent
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Clorprenaline D7Cat No HY-131106S
Clorprenaline D7 is a deuterium labeledClorprenaline Clorprenaline is a β2-adrenergic
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clorprenaline hydrochlorideCat No HY-B1347
Clorprenaline hydrochloride is a β -adrenergic2
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
8 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
D2343Cat No HY-U00206
D2343 is a agonist and also is anβ2-adrenoceptor inhibitorα1- adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Dabuzalgron (Ro 115-1240) Cat No HY-117071
Dabuzalgron (Ro 115-1240) is an orally active andselective agonist forα-1A adrenergic receptorthe treatment of urinary incontinence Dabuzalgronprotects against Doxorubicin-inducedcardiotoxicity by preserving mitochondrialfunction
Purity 9872Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Dapiprazole hydrochlorideCat No HY-A0142A
Dapiprazole hydrochloride is a potent α-adrenergicblocking drug which is used to reverse mydriasisafter eye examination
Purity 9997Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
Deriglidole (SL 86-0715) Cat No HY-101683
Deriglidole is a peripheral adrenoceptorantagonist with a high affinity forα -adrenoceptors2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DetomidineCat No HY-B0163
Detomidine produce dose-dependent sedative andanalgesic effects is a nonnarcotic syntheticα2-adrenergic agonist Target α2-adrenergicagonist Detomidine is an imidazole derivative andα2-adrenergic agonist used as a large animalsedative primarily used in horses
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Detomidine carboxylic acidCat No HY-135895
Detomidine carboxylic acid is the major urinarymetabolite of Detomidine Detomidine is asynthetic agonist and an animalα2-adrenergicanalgesic sedative Detomidine also has cardiacand respiratory effects and an antidiureticaction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Detomidine hydrochlorideCat No HY-B0163A
Detomidine hydrochloride produce dose-dependentsedative and analgesic effects is a nonnarcoticsynthetic α2-adrenergic agonist Targetα2-adrenergic agonist Detomidine is an imidazolederivative and α2-adrenergic agonist used as alarge animal sedative primarily used inhellip
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Dexmedetomidine hydrochloride ((+)-Medetomidine
hydrochloride (S)-Medetomidine hydrochloride) Cat No HY-17034A
Dexmedetomidine Hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9854Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg
Diacetolol D7Cat No HY-100635S
Diacetolol D7 is a deuterium labeled DiacetololDiacetolol is the major metabolite of AcebutololDiacetolol is a blocking andβ-adrenoceptoranti-arrhythmic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DicentrineCat No HY-N6969
Dicentrine is a natural product isolated from theplant with antihypertensiveLindera megaphyllaeffect Dicentrine is an α -adrenoceptor1
antagonist which has effective against humanhyperplastic prostates
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 9
DL-Epinephrine ((plusmn)-Epinephrine DL-Adrenaline (plusmn)-Adrenaline) Cat No HY-B0447
DL-Epinephrine is the racemate of epinephrineL-Epinephrine is a hormone secreted by the medullaof the adrenal glands L-Epinephrine is an
and receptor agonistα-adrenergic β-adrenergic
Purity gt990Clinical Data No Development ReportedSize 500 mg 1 g 5 g
DL-Norepinephrine hydrochlorideCat No HY-N7142
DL-Norepinephrine hydrochloride is a syntheticphenylethylamine that mimics the sympathomimeticactions of the endogenousnorepinephrineDL-Norepinephrine hydrochloride isa neurotransmitter targets α1 and β1
has an increasing effecthellipadrenoceptors
Purity 9953Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Dobutamine hydrochlorideCat No HY-15746
Dobutamine hydrochloride is a syntheticcatecholamine that acts on α1-AR β1-AR β2-AR
Dobutamine(α-1 β-1 andβ-2 adrenoceptors)hydrochloride is a selective β1-AR agonistrelatively weak activity at α1-AR and β2-AR
Purity 9947Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Dopexamine hydrochloride (FPL60278AR) Cat No HY-U00205
Dopexamine hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin (UK 33274) Cat No HY-B0098
Doxazosin (UK 33274) is a quinazoline-derivativethat selectively antagonizes postsynaptic
α1-adrenergic receptors
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin D8 (UK 33274 D8) Cat No HY-B0098S
Doxazosin D8 (UK 33274 D8) is a deuterium labeledDoxazosin (UK 33274) Doxazosin is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1 adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Doxazosin mesylate (UK 33274 mesylate) Cat No HY-B0098A
Doxazosin mesylate (UK 33274) is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1-adrenergic receptors
Purity 9860Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
EcastololCat No HY-101691
Ecastolol is a beta adrenergic receptorantagonist with antianginal activities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Epanolol (Visacor ICI141292) Cat No HY-U00183
Epanolol (Visacor ICI141292) is a potent partial agonist with a greaterβ-adrenoceptor
affinity for - than β2-adrenoceptorsβ1
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Esmolol hydrochlorideCat No HY-B1392
Esmolol hydrochloride is a beta adrenergicreceptor blocker
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
10 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Falintolol (Z)-Cat No HY-U00283
Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oximefunction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenmetozole TosylateCat No HY-U00402
Fenmetozole Tosylate is an antagonist of theactions of ethanol also antagonizes α2-adrenergic
and acts as an antidepressant drugreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenoterol (Th-1165 Phenoterol) Cat No HY-B0976
Fenoterol is a β 2 adrenergic agonist designed toopen up the airways to the lungs is classed assympathomimetic β2 agonist and asthma medication
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Fenoterol hydrobromide (Fenoterol bromide Th-1165a Phenoterol hydrobromide) Cat No HY-B0976A
Fenoterol hydrobromide is a β 2 adrenergic agonistdesigned to open up the airways to the lungs isclassed as sympathomimetic β2 agonist and asthmamedication
Purity 9971Clinical Data LaunchedSize 100 mg
Fenspiride HydrochlorideCat No HY-A0027
Fenspiride Hcl is an α adrenergic and H1 histaminereceptor antagonist IC50 value TargetAdrenergic receptor H1 receptor Fenspiridehydrochloride is a bronchodilator withanti-inflammatory properties
Purity 9903Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
FiduxosinCat No HY-U00399
Fiduxosin is a potent antagonistα1-adrenoceptorwith of 0160 nM 249 nM and 0920 nM forKi
α1a- α1b- and α1d-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg
Formoterol Fumarate (Formoterol) Cat No HY-B0010
Formoterol fumarate(Foradil) is a potentselective and long-acting β2-adrenoceptor agonist
Purity 9894Clinical Data LaunchedSize 10 mg 50 mg
G-Protein antagonist peptideCat No HY-P1376
G-Protein antagonist peptide is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
G-Protein antagonist peptide TFACat No HY-P1376A
G-Protein antagonist peptide TFA is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide TFA competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Glaucine (OO-Dimethylisoboldine S-(+)-Glaucine NSC 34396) Cat No HY-N3945
Glaucine (OO-Dimethylisoboldine) is an alkaloidisolated from Crantz withGlaucium flavumantitussive bronchodilation and anti-inflammatoryproperties
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 11
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
12 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
14 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
16 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
18 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
20 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Brombuterol D9 hydrochloride (Bromobuterol D9 hydrochloride) Cat No HY-131104AS
Brombuterol D9 hydrochloride (Bromobuterol D9hydrochloride) is a deuterium labeled Brombuterolhydrochloride Brombuterol hydrochloride is a
agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Brombuterol hydrochloride (Bromobuterol hydrochloride) Cat No HY-131145
Brombuterol hydrochloride (Bromobuterolhydrochloride) is a agonistβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
BucindololCat No HY-103214
Bucindolol is a blockerβ1-adrenergic receptorwith intrinsic sympathomimetic activity used inthe research of heart failure
Purity gt990Clinical Data No Development ReportedSize 1 mg 5 mg
Carbazochrome sodium sulfonate (AC-17) Cat No HY-B0491A
Carbazochrome (sodium sulfonate) (AC-17) is anantihemorrhagic agent
Purity 9951Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carteolol hydrochloride (OPC-1085 hydrochloride) Cat No HY-17495A
Carteolol hydrochloride (OPC-1085 hydrochloride)is a non-selective beta blocker used to treatglaucoma
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Carvedilol (BM 14190) Cat No HY-B0006
Carvedilol (BM 14190) is a non-selective βα-1blocker Carvedilol inhibits lipid peroxidation ina dose-dependent manner with an IC of 5 μM50
Carvedilol is a multiple action antihypertensiveagent with potential use in angina and congestiveheart failure
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) Cat No HY-B0006A
Carvedilol phosphate hemihydrate (BM 14190phosphate hemihydrate) is a non-selective βα-1blocker Carvedilol phosphate hemihydrate inhibits
with an IC of 5 μMlipid peroxidation 50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Centanafadine (EB-1020) Cat No HY-16736
Centanafadine is dual norepinephrine (NE)dopamine transporter inhibitor also inhibits(DA)
serotonin transporter with of 6 nM 38 nMIC s50
and 83 nM for human NE DA and serotonintransporter respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Centanafadine hydrochloride (EB-1020 hydrochloride) Cat No HY-16736A
Centanafadine (hydrochloride) is dual transporternorepinephrine (NE)dopamine (DA)
inhibitor also inhibits serotonin transporterwith of 6 nM 38 nM and 83 nM for human NEIC s50
DA and serotonin transporter respectively
Purity 9993Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
CGP 20712 A (CGP 20712 mesylate) Cat No HY-101355B
CGP 20712 A (CGP 20712 mesylate) is a highlyselective ltBgtβ1-adrenoceptorltBgtantagonist with an of 07 nM CGP 20712 AIC50
exhibits ~10000-fold selectivity overβ2-adrenoceptors
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
wwwMedChemExpresscom 7
Cicloprolol hydrochlorideCat No HY-U00066
Cicloprolol is a partial β 1-adrenoceptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimaterol-D7Cat No HY-100935S
Cimaterol-D7 is the deuterium labeled CimaterolCimaterol is a potent agonist of β-adrenergicreceptors (pEC s=813 878 and 662 for human50
β1 β2 and β3 respectively) Cimaterol has beenused in farmed animals to increase carcass massand to alter muscle and fat deposition
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimbuterol-D9Cat No HY-131105S
Cimbuterol-D9 is the deuterium labeled CimbuterolCimbuterol is aβ-adrenergic agonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
CL 316243Cat No HY-116771A
CL316243 is a highly potent selective agonist with a of 3 nMβ3-adrenoceptor EC50
but is an extremely poor toβ12- receptors
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg
ClenproperolCat No HY-100699
Clenproperol is a agonistβ2-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clenproperol-D7Cat No HY-100699S
Clenproperol-D7 is the deuterium labeledClenproperol Clenproperol is a β2-adrenergicagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ClonidineCat No HY-12721
Clonidine is an agonist which isalpha 2-adrenergicused extensively in anesthesia research
Purity 9879Clinical Data LaunchedSize 1 mg 5 mg
Clonidine hydrochlorideCat No HY-B0409A
Clonidine hydrochloride is an agonist of and potent antihypertensiveα2-adrenoceptor
agent
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Clorprenaline D7Cat No HY-131106S
Clorprenaline D7 is a deuterium labeledClorprenaline Clorprenaline is a β2-adrenergic
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clorprenaline hydrochlorideCat No HY-B1347
Clorprenaline hydrochloride is a β -adrenergic2
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
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D2343Cat No HY-U00206
D2343 is a agonist and also is anβ2-adrenoceptor inhibitorα1- adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Dabuzalgron (Ro 115-1240) Cat No HY-117071
Dabuzalgron (Ro 115-1240) is an orally active andselective agonist forα-1A adrenergic receptorthe treatment of urinary incontinence Dabuzalgronprotects against Doxorubicin-inducedcardiotoxicity by preserving mitochondrialfunction
Purity 9872Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Dapiprazole hydrochlorideCat No HY-A0142A
Dapiprazole hydrochloride is a potent α-adrenergicblocking drug which is used to reverse mydriasisafter eye examination
Purity 9997Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
Deriglidole (SL 86-0715) Cat No HY-101683
Deriglidole is a peripheral adrenoceptorantagonist with a high affinity forα -adrenoceptors2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DetomidineCat No HY-B0163
Detomidine produce dose-dependent sedative andanalgesic effects is a nonnarcotic syntheticα2-adrenergic agonist Target α2-adrenergicagonist Detomidine is an imidazole derivative andα2-adrenergic agonist used as a large animalsedative primarily used in horses
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Detomidine carboxylic acidCat No HY-135895
Detomidine carboxylic acid is the major urinarymetabolite of Detomidine Detomidine is asynthetic agonist and an animalα2-adrenergicanalgesic sedative Detomidine also has cardiacand respiratory effects and an antidiureticaction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Detomidine hydrochlorideCat No HY-B0163A
Detomidine hydrochloride produce dose-dependentsedative and analgesic effects is a nonnarcoticsynthetic α2-adrenergic agonist Targetα2-adrenergic agonist Detomidine is an imidazolederivative and α2-adrenergic agonist used as alarge animal sedative primarily used inhellip
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Dexmedetomidine hydrochloride ((+)-Medetomidine
hydrochloride (S)-Medetomidine hydrochloride) Cat No HY-17034A
Dexmedetomidine Hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9854Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg
Diacetolol D7Cat No HY-100635S
Diacetolol D7 is a deuterium labeled DiacetololDiacetolol is the major metabolite of AcebutololDiacetolol is a blocking andβ-adrenoceptoranti-arrhythmic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DicentrineCat No HY-N6969
Dicentrine is a natural product isolated from theplant with antihypertensiveLindera megaphyllaeffect Dicentrine is an α -adrenoceptor1
antagonist which has effective against humanhyperplastic prostates
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 9
DL-Epinephrine ((plusmn)-Epinephrine DL-Adrenaline (plusmn)-Adrenaline) Cat No HY-B0447
DL-Epinephrine is the racemate of epinephrineL-Epinephrine is a hormone secreted by the medullaof the adrenal glands L-Epinephrine is an
and receptor agonistα-adrenergic β-adrenergic
Purity gt990Clinical Data No Development ReportedSize 500 mg 1 g 5 g
DL-Norepinephrine hydrochlorideCat No HY-N7142
DL-Norepinephrine hydrochloride is a syntheticphenylethylamine that mimics the sympathomimeticactions of the endogenousnorepinephrineDL-Norepinephrine hydrochloride isa neurotransmitter targets α1 and β1
has an increasing effecthellipadrenoceptors
Purity 9953Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Dobutamine hydrochlorideCat No HY-15746
Dobutamine hydrochloride is a syntheticcatecholamine that acts on α1-AR β1-AR β2-AR
Dobutamine(α-1 β-1 andβ-2 adrenoceptors)hydrochloride is a selective β1-AR agonistrelatively weak activity at α1-AR and β2-AR
Purity 9947Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Dopexamine hydrochloride (FPL60278AR) Cat No HY-U00205
Dopexamine hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin (UK 33274) Cat No HY-B0098
Doxazosin (UK 33274) is a quinazoline-derivativethat selectively antagonizes postsynaptic
α1-adrenergic receptors
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin D8 (UK 33274 D8) Cat No HY-B0098S
Doxazosin D8 (UK 33274 D8) is a deuterium labeledDoxazosin (UK 33274) Doxazosin is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1 adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Doxazosin mesylate (UK 33274 mesylate) Cat No HY-B0098A
Doxazosin mesylate (UK 33274) is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1-adrenergic receptors
Purity 9860Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
EcastololCat No HY-101691
Ecastolol is a beta adrenergic receptorantagonist with antianginal activities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Epanolol (Visacor ICI141292) Cat No HY-U00183
Epanolol (Visacor ICI141292) is a potent partial agonist with a greaterβ-adrenoceptor
affinity for - than β2-adrenoceptorsβ1
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Esmolol hydrochlorideCat No HY-B1392
Esmolol hydrochloride is a beta adrenergicreceptor blocker
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
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Falintolol (Z)-Cat No HY-U00283
Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oximefunction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenmetozole TosylateCat No HY-U00402
Fenmetozole Tosylate is an antagonist of theactions of ethanol also antagonizes α2-adrenergic
and acts as an antidepressant drugreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenoterol (Th-1165 Phenoterol) Cat No HY-B0976
Fenoterol is a β 2 adrenergic agonist designed toopen up the airways to the lungs is classed assympathomimetic β2 agonist and asthma medication
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Fenoterol hydrobromide (Fenoterol bromide Th-1165a Phenoterol hydrobromide) Cat No HY-B0976A
Fenoterol hydrobromide is a β 2 adrenergic agonistdesigned to open up the airways to the lungs isclassed as sympathomimetic β2 agonist and asthmamedication
Purity 9971Clinical Data LaunchedSize 100 mg
Fenspiride HydrochlorideCat No HY-A0027
Fenspiride Hcl is an α adrenergic and H1 histaminereceptor antagonist IC50 value TargetAdrenergic receptor H1 receptor Fenspiridehydrochloride is a bronchodilator withanti-inflammatory properties
Purity 9903Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
FiduxosinCat No HY-U00399
Fiduxosin is a potent antagonistα1-adrenoceptorwith of 0160 nM 249 nM and 0920 nM forKi
α1a- α1b- and α1d-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg
Formoterol Fumarate (Formoterol) Cat No HY-B0010
Formoterol fumarate(Foradil) is a potentselective and long-acting β2-adrenoceptor agonist
Purity 9894Clinical Data LaunchedSize 10 mg 50 mg
G-Protein antagonist peptideCat No HY-P1376
G-Protein antagonist peptide is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
G-Protein antagonist peptide TFACat No HY-P1376A
G-Protein antagonist peptide TFA is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide TFA competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Glaucine (OO-Dimethylisoboldine S-(+)-Glaucine NSC 34396) Cat No HY-N3945
Glaucine (OO-Dimethylisoboldine) is an alkaloidisolated from Crantz withGlaucium flavumantitussive bronchodilation and anti-inflammatoryproperties
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 11
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
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Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
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NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
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RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
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TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Cicloprolol hydrochlorideCat No HY-U00066
Cicloprolol is a partial β 1-adrenoceptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimaterol-D7Cat No HY-100935S
Cimaterol-D7 is the deuterium labeled CimaterolCimaterol is a potent agonist of β-adrenergicreceptors (pEC s=813 878 and 662 for human50
β1 β2 and β3 respectively) Cimaterol has beenused in farmed animals to increase carcass massand to alter muscle and fat deposition
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Cimbuterol-D9Cat No HY-131105S
Cimbuterol-D9 is the deuterium labeled CimbuterolCimbuterol is aβ-adrenergic agonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
CL 316243Cat No HY-116771A
CL316243 is a highly potent selective agonist with a of 3 nMβ3-adrenoceptor EC50
but is an extremely poor toβ12- receptors
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg
ClenproperolCat No HY-100699
Clenproperol is a agonistβ2-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clenproperol-D7Cat No HY-100699S
Clenproperol-D7 is the deuterium labeledClenproperol Clenproperol is a β2-adrenergicagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
ClonidineCat No HY-12721
Clonidine is an agonist which isalpha 2-adrenergicused extensively in anesthesia research
Purity 9879Clinical Data LaunchedSize 1 mg 5 mg
Clonidine hydrochlorideCat No HY-B0409A
Clonidine hydrochloride is an agonist of and potent antihypertensiveα2-adrenoceptor
agent
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Clorprenaline D7Cat No HY-131106S
Clorprenaline D7 is a deuterium labeledClorprenaline Clorprenaline is a β2-adrenergic
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Clorprenaline hydrochlorideCat No HY-B1347
Clorprenaline hydrochloride is a β -adrenergic2
agonist that is implicated in bronchialreceptorexpansion Clorprenaline has the potential forasthma research
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
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D2343Cat No HY-U00206
D2343 is a agonist and also is anβ2-adrenoceptor inhibitorα1- adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Dabuzalgron (Ro 115-1240) Cat No HY-117071
Dabuzalgron (Ro 115-1240) is an orally active andselective agonist forα-1A adrenergic receptorthe treatment of urinary incontinence Dabuzalgronprotects against Doxorubicin-inducedcardiotoxicity by preserving mitochondrialfunction
Purity 9872Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Dapiprazole hydrochlorideCat No HY-A0142A
Dapiprazole hydrochloride is a potent α-adrenergicblocking drug which is used to reverse mydriasisafter eye examination
Purity 9997Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
Deriglidole (SL 86-0715) Cat No HY-101683
Deriglidole is a peripheral adrenoceptorantagonist with a high affinity forα -adrenoceptors2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DetomidineCat No HY-B0163
Detomidine produce dose-dependent sedative andanalgesic effects is a nonnarcotic syntheticα2-adrenergic agonist Target α2-adrenergicagonist Detomidine is an imidazole derivative andα2-adrenergic agonist used as a large animalsedative primarily used in horses
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Detomidine carboxylic acidCat No HY-135895
Detomidine carboxylic acid is the major urinarymetabolite of Detomidine Detomidine is asynthetic agonist and an animalα2-adrenergicanalgesic sedative Detomidine also has cardiacand respiratory effects and an antidiureticaction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Detomidine hydrochlorideCat No HY-B0163A
Detomidine hydrochloride produce dose-dependentsedative and analgesic effects is a nonnarcoticsynthetic α2-adrenergic agonist Targetα2-adrenergic agonist Detomidine is an imidazolederivative and α2-adrenergic agonist used as alarge animal sedative primarily used inhellip
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Dexmedetomidine hydrochloride ((+)-Medetomidine
hydrochloride (S)-Medetomidine hydrochloride) Cat No HY-17034A
Dexmedetomidine Hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9854Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg
Diacetolol D7Cat No HY-100635S
Diacetolol D7 is a deuterium labeled DiacetololDiacetolol is the major metabolite of AcebutololDiacetolol is a blocking andβ-adrenoceptoranti-arrhythmic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DicentrineCat No HY-N6969
Dicentrine is a natural product isolated from theplant with antihypertensiveLindera megaphyllaeffect Dicentrine is an α -adrenoceptor1
antagonist which has effective against humanhyperplastic prostates
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 9
DL-Epinephrine ((plusmn)-Epinephrine DL-Adrenaline (plusmn)-Adrenaline) Cat No HY-B0447
DL-Epinephrine is the racemate of epinephrineL-Epinephrine is a hormone secreted by the medullaof the adrenal glands L-Epinephrine is an
and receptor agonistα-adrenergic β-adrenergic
Purity gt990Clinical Data No Development ReportedSize 500 mg 1 g 5 g
DL-Norepinephrine hydrochlorideCat No HY-N7142
DL-Norepinephrine hydrochloride is a syntheticphenylethylamine that mimics the sympathomimeticactions of the endogenousnorepinephrineDL-Norepinephrine hydrochloride isa neurotransmitter targets α1 and β1
has an increasing effecthellipadrenoceptors
Purity 9953Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Dobutamine hydrochlorideCat No HY-15746
Dobutamine hydrochloride is a syntheticcatecholamine that acts on α1-AR β1-AR β2-AR
Dobutamine(α-1 β-1 andβ-2 adrenoceptors)hydrochloride is a selective β1-AR agonistrelatively weak activity at α1-AR and β2-AR
Purity 9947Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Dopexamine hydrochloride (FPL60278AR) Cat No HY-U00205
Dopexamine hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin (UK 33274) Cat No HY-B0098
Doxazosin (UK 33274) is a quinazoline-derivativethat selectively antagonizes postsynaptic
α1-adrenergic receptors
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin D8 (UK 33274 D8) Cat No HY-B0098S
Doxazosin D8 (UK 33274 D8) is a deuterium labeledDoxazosin (UK 33274) Doxazosin is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1 adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Doxazosin mesylate (UK 33274 mesylate) Cat No HY-B0098A
Doxazosin mesylate (UK 33274) is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1-adrenergic receptors
Purity 9860Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
EcastololCat No HY-101691
Ecastolol is a beta adrenergic receptorantagonist with antianginal activities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Epanolol (Visacor ICI141292) Cat No HY-U00183
Epanolol (Visacor ICI141292) is a potent partial agonist with a greaterβ-adrenoceptor
affinity for - than β2-adrenoceptorsβ1
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Esmolol hydrochlorideCat No HY-B1392
Esmolol hydrochloride is a beta adrenergicreceptor blocker
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
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Falintolol (Z)-Cat No HY-U00283
Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oximefunction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenmetozole TosylateCat No HY-U00402
Fenmetozole Tosylate is an antagonist of theactions of ethanol also antagonizes α2-adrenergic
and acts as an antidepressant drugreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenoterol (Th-1165 Phenoterol) Cat No HY-B0976
Fenoterol is a β 2 adrenergic agonist designed toopen up the airways to the lungs is classed assympathomimetic β2 agonist and asthma medication
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Fenoterol hydrobromide (Fenoterol bromide Th-1165a Phenoterol hydrobromide) Cat No HY-B0976A
Fenoterol hydrobromide is a β 2 adrenergic agonistdesigned to open up the airways to the lungs isclassed as sympathomimetic β2 agonist and asthmamedication
Purity 9971Clinical Data LaunchedSize 100 mg
Fenspiride HydrochlorideCat No HY-A0027
Fenspiride Hcl is an α adrenergic and H1 histaminereceptor antagonist IC50 value TargetAdrenergic receptor H1 receptor Fenspiridehydrochloride is a bronchodilator withanti-inflammatory properties
Purity 9903Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
FiduxosinCat No HY-U00399
Fiduxosin is a potent antagonistα1-adrenoceptorwith of 0160 nM 249 nM and 0920 nM forKi
α1a- α1b- and α1d-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg
Formoterol Fumarate (Formoterol) Cat No HY-B0010
Formoterol fumarate(Foradil) is a potentselective and long-acting β2-adrenoceptor agonist
Purity 9894Clinical Data LaunchedSize 10 mg 50 mg
G-Protein antagonist peptideCat No HY-P1376
G-Protein antagonist peptide is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
G-Protein antagonist peptide TFACat No HY-P1376A
G-Protein antagonist peptide TFA is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide TFA competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Glaucine (OO-Dimethylisoboldine S-(+)-Glaucine NSC 34396) Cat No HY-N3945
Glaucine (OO-Dimethylisoboldine) is an alkaloidisolated from Crantz withGlaucium flavumantitussive bronchodilation and anti-inflammatoryproperties
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 11
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
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Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
18 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
D2343Cat No HY-U00206
D2343 is a agonist and also is anβ2-adrenoceptor inhibitorα1- adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Dabuzalgron (Ro 115-1240) Cat No HY-117071
Dabuzalgron (Ro 115-1240) is an orally active andselective agonist forα-1A adrenergic receptorthe treatment of urinary incontinence Dabuzalgronprotects against Doxorubicin-inducedcardiotoxicity by preserving mitochondrialfunction
Purity 9872Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Dapiprazole hydrochlorideCat No HY-A0142A
Dapiprazole hydrochloride is a potent α-adrenergicblocking drug which is used to reverse mydriasisafter eye examination
Purity 9997Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
Deriglidole (SL 86-0715) Cat No HY-101683
Deriglidole is a peripheral adrenoceptorantagonist with a high affinity forα -adrenoceptors2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DetomidineCat No HY-B0163
Detomidine produce dose-dependent sedative andanalgesic effects is a nonnarcotic syntheticα2-adrenergic agonist Target α2-adrenergicagonist Detomidine is an imidazole derivative andα2-adrenergic agonist used as a large animalsedative primarily used in horses
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Detomidine carboxylic acidCat No HY-135895
Detomidine carboxylic acid is the major urinarymetabolite of Detomidine Detomidine is asynthetic agonist and an animalα2-adrenergicanalgesic sedative Detomidine also has cardiacand respiratory effects and an antidiureticaction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Detomidine hydrochlorideCat No HY-B0163A
Detomidine hydrochloride produce dose-dependentsedative and analgesic effects is a nonnarcoticsynthetic α2-adrenergic agonist Targetα2-adrenergic agonist Detomidine is an imidazolederivative and α2-adrenergic agonist used as alarge animal sedative primarily used inhellip
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Dexmedetomidine hydrochloride ((+)-Medetomidine
hydrochloride (S)-Medetomidine hydrochloride) Cat No HY-17034A
Dexmedetomidine Hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9854Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg
Diacetolol D7Cat No HY-100635S
Diacetolol D7 is a deuterium labeled DiacetololDiacetolol is the major metabolite of AcebutololDiacetolol is a blocking andβ-adrenoceptoranti-arrhythmic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
DicentrineCat No HY-N6969
Dicentrine is a natural product isolated from theplant with antihypertensiveLindera megaphyllaeffect Dicentrine is an α -adrenoceptor1
antagonist which has effective against humanhyperplastic prostates
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 9
DL-Epinephrine ((plusmn)-Epinephrine DL-Adrenaline (plusmn)-Adrenaline) Cat No HY-B0447
DL-Epinephrine is the racemate of epinephrineL-Epinephrine is a hormone secreted by the medullaof the adrenal glands L-Epinephrine is an
and receptor agonistα-adrenergic β-adrenergic
Purity gt990Clinical Data No Development ReportedSize 500 mg 1 g 5 g
DL-Norepinephrine hydrochlorideCat No HY-N7142
DL-Norepinephrine hydrochloride is a syntheticphenylethylamine that mimics the sympathomimeticactions of the endogenousnorepinephrineDL-Norepinephrine hydrochloride isa neurotransmitter targets α1 and β1
has an increasing effecthellipadrenoceptors
Purity 9953Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Dobutamine hydrochlorideCat No HY-15746
Dobutamine hydrochloride is a syntheticcatecholamine that acts on α1-AR β1-AR β2-AR
Dobutamine(α-1 β-1 andβ-2 adrenoceptors)hydrochloride is a selective β1-AR agonistrelatively weak activity at α1-AR and β2-AR
Purity 9947Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Dopexamine hydrochloride (FPL60278AR) Cat No HY-U00205
Dopexamine hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin (UK 33274) Cat No HY-B0098
Doxazosin (UK 33274) is a quinazoline-derivativethat selectively antagonizes postsynaptic
α1-adrenergic receptors
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin D8 (UK 33274 D8) Cat No HY-B0098S
Doxazosin D8 (UK 33274 D8) is a deuterium labeledDoxazosin (UK 33274) Doxazosin is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1 adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Doxazosin mesylate (UK 33274 mesylate) Cat No HY-B0098A
Doxazosin mesylate (UK 33274) is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1-adrenergic receptors
Purity 9860Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
EcastololCat No HY-101691
Ecastolol is a beta adrenergic receptorantagonist with antianginal activities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Epanolol (Visacor ICI141292) Cat No HY-U00183
Epanolol (Visacor ICI141292) is a potent partial agonist with a greaterβ-adrenoceptor
affinity for - than β2-adrenoceptorsβ1
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Esmolol hydrochlorideCat No HY-B1392
Esmolol hydrochloride is a beta adrenergicreceptor blocker
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
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Falintolol (Z)-Cat No HY-U00283
Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oximefunction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenmetozole TosylateCat No HY-U00402
Fenmetozole Tosylate is an antagonist of theactions of ethanol also antagonizes α2-adrenergic
and acts as an antidepressant drugreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenoterol (Th-1165 Phenoterol) Cat No HY-B0976
Fenoterol is a β 2 adrenergic agonist designed toopen up the airways to the lungs is classed assympathomimetic β2 agonist and asthma medication
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Fenoterol hydrobromide (Fenoterol bromide Th-1165a Phenoterol hydrobromide) Cat No HY-B0976A
Fenoterol hydrobromide is a β 2 adrenergic agonistdesigned to open up the airways to the lungs isclassed as sympathomimetic β2 agonist and asthmamedication
Purity 9971Clinical Data LaunchedSize 100 mg
Fenspiride HydrochlorideCat No HY-A0027
Fenspiride Hcl is an α adrenergic and H1 histaminereceptor antagonist IC50 value TargetAdrenergic receptor H1 receptor Fenspiridehydrochloride is a bronchodilator withanti-inflammatory properties
Purity 9903Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
FiduxosinCat No HY-U00399
Fiduxosin is a potent antagonistα1-adrenoceptorwith of 0160 nM 249 nM and 0920 nM forKi
α1a- α1b- and α1d-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg
Formoterol Fumarate (Formoterol) Cat No HY-B0010
Formoterol fumarate(Foradil) is a potentselective and long-acting β2-adrenoceptor agonist
Purity 9894Clinical Data LaunchedSize 10 mg 50 mg
G-Protein antagonist peptideCat No HY-P1376
G-Protein antagonist peptide is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
G-Protein antagonist peptide TFACat No HY-P1376A
G-Protein antagonist peptide TFA is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide TFA competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Glaucine (OO-Dimethylisoboldine S-(+)-Glaucine NSC 34396) Cat No HY-N3945
Glaucine (OO-Dimethylisoboldine) is an alkaloidisolated from Crantz withGlaucium flavumantitussive bronchodilation and anti-inflammatoryproperties
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 11
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
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Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
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NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
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RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
DL-Epinephrine ((plusmn)-Epinephrine DL-Adrenaline (plusmn)-Adrenaline) Cat No HY-B0447
DL-Epinephrine is the racemate of epinephrineL-Epinephrine is a hormone secreted by the medullaof the adrenal glands L-Epinephrine is an
and receptor agonistα-adrenergic β-adrenergic
Purity gt990Clinical Data No Development ReportedSize 500 mg 1 g 5 g
DL-Norepinephrine hydrochlorideCat No HY-N7142
DL-Norepinephrine hydrochloride is a syntheticphenylethylamine that mimics the sympathomimeticactions of the endogenousnorepinephrineDL-Norepinephrine hydrochloride isa neurotransmitter targets α1 and β1
has an increasing effecthellipadrenoceptors
Purity 9953Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Dobutamine hydrochlorideCat No HY-15746
Dobutamine hydrochloride is a syntheticcatecholamine that acts on α1-AR β1-AR β2-AR
Dobutamine(α-1 β-1 andβ-2 adrenoceptors)hydrochloride is a selective β1-AR agonistrelatively weak activity at α1-AR and β2-AR
Purity 9947Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Dopexamine hydrochloride (FPL60278AR) Cat No HY-U00205
Dopexamine hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin (UK 33274) Cat No HY-B0098
Doxazosin (UK 33274) is a quinazoline-derivativethat selectively antagonizes postsynaptic
α1-adrenergic receptors
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Doxazosin D8 (UK 33274 D8) Cat No HY-B0098S
Doxazosin D8 (UK 33274 D8) is a deuterium labeledDoxazosin (UK 33274) Doxazosin is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1 adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Doxazosin mesylate (UK 33274 mesylate) Cat No HY-B0098A
Doxazosin mesylate (UK 33274) is aquinazoline-derivative that selectivelyantagonizes postsynaptic α1-adrenergic receptors
Purity 9860Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
EcastololCat No HY-101691
Ecastolol is a beta adrenergic receptorantagonist with antianginal activities
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Epanolol (Visacor ICI141292) Cat No HY-U00183
Epanolol (Visacor ICI141292) is a potent partial agonist with a greaterβ-adrenoceptor
affinity for - than β2-adrenoceptorsβ1
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Esmolol hydrochlorideCat No HY-B1392
Esmolol hydrochloride is a beta adrenergicreceptor blocker
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
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Falintolol (Z)-Cat No HY-U00283
Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oximefunction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenmetozole TosylateCat No HY-U00402
Fenmetozole Tosylate is an antagonist of theactions of ethanol also antagonizes α2-adrenergic
and acts as an antidepressant drugreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenoterol (Th-1165 Phenoterol) Cat No HY-B0976
Fenoterol is a β 2 adrenergic agonist designed toopen up the airways to the lungs is classed assympathomimetic β2 agonist and asthma medication
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Fenoterol hydrobromide (Fenoterol bromide Th-1165a Phenoterol hydrobromide) Cat No HY-B0976A
Fenoterol hydrobromide is a β 2 adrenergic agonistdesigned to open up the airways to the lungs isclassed as sympathomimetic β2 agonist and asthmamedication
Purity 9971Clinical Data LaunchedSize 100 mg
Fenspiride HydrochlorideCat No HY-A0027
Fenspiride Hcl is an α adrenergic and H1 histaminereceptor antagonist IC50 value TargetAdrenergic receptor H1 receptor Fenspiridehydrochloride is a bronchodilator withanti-inflammatory properties
Purity 9903Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
FiduxosinCat No HY-U00399
Fiduxosin is a potent antagonistα1-adrenoceptorwith of 0160 nM 249 nM and 0920 nM forKi
α1a- α1b- and α1d-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg
Formoterol Fumarate (Formoterol) Cat No HY-B0010
Formoterol fumarate(Foradil) is a potentselective and long-acting β2-adrenoceptor agonist
Purity 9894Clinical Data LaunchedSize 10 mg 50 mg
G-Protein antagonist peptideCat No HY-P1376
G-Protein antagonist peptide is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
G-Protein antagonist peptide TFACat No HY-P1376A
G-Protein antagonist peptide TFA is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide TFA competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Glaucine (OO-Dimethylisoboldine S-(+)-Glaucine NSC 34396) Cat No HY-N3945
Glaucine (OO-Dimethylisoboldine) is an alkaloidisolated from Crantz withGlaucium flavumantitussive bronchodilation and anti-inflammatoryproperties
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 11
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
14 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
16 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
18 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Falintolol (Z)-Cat No HY-U00283
Falintolol (Z)- a new antagonist isβ-adrenergiccharacterized by the presence of an oximefunction
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenmetozole TosylateCat No HY-U00402
Fenmetozole Tosylate is an antagonist of theactions of ethanol also antagonizes α2-adrenergic
and acts as an antidepressant drugreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Fenoterol (Th-1165 Phenoterol) Cat No HY-B0976
Fenoterol is a β 2 adrenergic agonist designed toopen up the airways to the lungs is classed assympathomimetic β2 agonist and asthma medication
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Fenoterol hydrobromide (Fenoterol bromide Th-1165a Phenoterol hydrobromide) Cat No HY-B0976A
Fenoterol hydrobromide is a β 2 adrenergic agonistdesigned to open up the airways to the lungs isclassed as sympathomimetic β2 agonist and asthmamedication
Purity 9971Clinical Data LaunchedSize 100 mg
Fenspiride HydrochlorideCat No HY-A0027
Fenspiride Hcl is an α adrenergic and H1 histaminereceptor antagonist IC50 value TargetAdrenergic receptor H1 receptor Fenspiridehydrochloride is a bronchodilator withanti-inflammatory properties
Purity 9903Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
FiduxosinCat No HY-U00399
Fiduxosin is a potent antagonistα1-adrenoceptorwith of 0160 nM 249 nM and 0920 nM forKi
α1a- α1b- and α1d-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg
Formoterol Fumarate (Formoterol) Cat No HY-B0010
Formoterol fumarate(Foradil) is a potentselective and long-acting β2-adrenoceptor agonist
Purity 9894Clinical Data LaunchedSize 10 mg 50 mg
G-Protein antagonist peptideCat No HY-P1376
G-Protein antagonist peptide is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
G-Protein antagonist peptide TFACat No HY-P1376A
G-Protein antagonist peptide TFA is the substanceP-related peptide that inhibits binding of Gproteins to their receptors G-Protein antagonistpeptide TFA competitively and reversibly inhibits
activation of Gi or GoM2 muscarinic receptorand inhibits Gs activation by β-adrenoceptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Glaucine (OO-Dimethylisoboldine S-(+)-Glaucine NSC 34396) Cat No HY-N3945
Glaucine (OO-Dimethylisoboldine) is an alkaloidisolated from Crantz withGlaucium flavumantitussive bronchodilation and anti-inflammatoryproperties
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 11
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
16 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
18 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
20 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Gramine (Donaxine) Cat No HY-N0166
Gramine (Donaxine) is a natural alkaloid isolatedfrom giant reed acts as an active adiponectin
agonist with s of 32 andreceptor (AdipoR) IC50
42 microM for AdipoR2 and AdipoR1 respectivelyGramine is also a human and mouse β2-Adrenergic
agonistreceptor (β2-AR)
Purity 9945Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg
Guanabenz Acetate (BR-750 Wy8678 acetate) Cat No HY-B0566
Guanabenz (Acetate) (BR-750) is an alpha-2selective adrenergic agonist used as anantihypertensive agent
Purity 9888Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
GuanfacineCat No HY-17416A
Guanfacine is a selective α2A receptor agonistTarget α2A Receptor Guanfacine is asympatholytic It is a selective α2A receptoragonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Guanfacine hydrochlorideCat No HY-17416
Guanfacine hydrochloride an anti-hypertensiveagent is a selective α2A-adrenoceptor agonistwith Kd of 31 nM and displays 60-fold selectivityover α2B-adrenoceptors IC50 Value 31 nM(Kd)Target Adrenergic Receptor Guanfacine is asympatholytic
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Guanoxabenz (Hydroxyguanabenz) Cat No HY-U00123
Guanoxabenz is an α2 adrenergic receptoragonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Higenamine (Norcoclaurine) Cat No HY-N2037
Higenamine (Norcoclaurine) a β2-AR agonist is akey component of the Chinese herb aconite rootthat prescribes for treating symptoms of heartfailure in the oriental Asian countriesHigenamine (Norcoclaurine) has anti-apoptoticeffects
Purity gt98Clinical Data Phase 1Size 5 mg 10 mg 20 mg
Higenamine hydrochloride (Norcoclaurine hydrochloride) Cat No HY-N2037A
Higenamine hydrochloride (Norcoclaurinehydrochloride) a agonist is a keyβ2-ARcomponent of the Chinese herb aconite root thatprescribes for treating symptoms of heart failurein the oriental Asian countries
Purity 9904Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
HOKU-81 (4-Hydroxytulobuterol) Cat No HY-50291
HOKU-81 a new bronchodilator is one of themetabolites of tulobuterol IC50 Value TargetAdrenergic Receptor Effects of HOKU-81 on isolatedtrachea and atria of guinea pigs were comparedwith those of various bronchodilators
Purity gt950Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 25 mg
Hydrocortisone 17-butyrate (Cortisol 17-butyrate Hydrocortisone butyrate) Cat No HY-B0983
Hydrocortisone 17-butyrate is an adrenocorticohormone
Purity 9993Clinical Data LaunchedSize 10 mM times 1 mL 200 mg
HydroxybupropionCat No HY-100637
Hydroxybupropion is the major active metabolite ofBupropion Hydroxybupropion is metabolized byCYP2B6Bupropion is an atypical antidepressant andsmoking-cessation agent Hydroxybupropion inhibits
with an value of 17norepinephrine uptake IC50
μM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
wwwMedChemExpresscom 13
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
16 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
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NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
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RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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ICI 118551 hydrochloride (ICI 118551 hydrochloride) Cat No HY-13951
ICI 118551 (hydrochloride) is a highly selective antagonist with s ofβ2 adrenergic receptor Ki
07 495 and 611 nM for β2 β1 and β3 receptorsrespectively
Purity 9964Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Idazoxan hydrochloride (RX 781094 hydrochloride) Cat No HY-14561A
Idazoxan hydrochloride (RX 781094 hydrochloride)is an antagonist and is also aα -adrenoceptor2
antagonistimidazoline receptors (IRs)competitively antagonized the centrally inducedhypotensive effect of imidazoline-like drugs(IMs)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Imoxiterol (RP 58802B) Cat No HY-101585
Imoxiterol (RP 58802B) is a agonistβ-adrenergic
Purity gt980Clinical Data No Development ReportedSize 1 mg
IndacaterolCat No HY-14299
Indacaterol(Onbrez Arcapta) is anultra-long-acting β-adrenoceptor agonist IC50value Target β-adrenoceptor Indacaterol inhibitscAMP production in Chinese hamster ovary cellsstably transfected with human β2 adrenoceptorswith pEC50 of 806
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Indacaterol maleate (QAB149) Cat No HY-14299A
Indacaterol (QAB149) maleate is anultra-long-acting β-adrenoceptor agonist
Purity 9992Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
IndanidineCat No HY-101717
Indanidine is an agonistalpha-adrenergic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Indoramin D5 (Indoramine D5 Wy-21901 D5) Cat No HY-12760S
Indoramin D5 is deuterium labeled Indoramin whichis a piperidine antiadrenergic agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) Cat No HY-N0761
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid)is a cinnamic acid derivative that hasantidiabetic activity Isoferulic acid binds toand activates α1-adrenergic receptors (IC =14 microM)50
to enhance secretion of β-endorphin (EC =52250
nM) and increase glucose use
Purity 9982Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg
Isoprenaline hydrochloride (Isoproterenol hydrochloride) Cat No HY-B0468
Isoprenaline hydrochloride is a non-selective agonist with potentbeta-adrenergic receptor
peripheral vasodilator bronchodilator andcardiac stimulating activities
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 1 g
Isoxsuprine hydrochlorideCat No HY-B1270
Isoxsuprine hydrochloride is a beta-adrenergic agonist with s of 1365 μΜ and 348 μΜreceptor Ki
for myometrial and placcntal beta-adrenergicreceptor respectively Isoxsuprine hydrochlorideis also a antagonistNMDA receptor
Purity 9887Clinical Data No Development ReportedSize 200 mg
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Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
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LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
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Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
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NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Ivabradine D3 HydrochlorideCat No HY-B0162AS1
Ivabradine D3 Hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine D6 hydrochlorideCat No HY-B0162AS
Ivabradine D6 hydrochloride is the deuteriumlabeled Ivabradine hydrochloride Ivabradinehydrochloride is a new I inhibitor with IC of 29f 50
μM and used as a pure heart rate lowering agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ivabradine hydrochlorideCat No HY-B0162A
Ivabradine hydrochloride is an orallybioavailable hyperpolarization-activated cyclicnucleotide-gated ( ) channel blockerHCN
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
JP1302 dihydrochlorideCat No HY-103213
JP1302 dihydrochloride is a selective highaffinity antagonist of the alpha2C-adrenoceptor
with a value(α -adrenoceptor)2C Kb
(antagonist activity) of 16 nM and a K (bindingi
affinity) value of 28 nM
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Ko-3290Cat No HY-101721
Ko-3290 is an antagonist of withβ-adrenoceptorcardioselectivity and antilipolytic effects inanimals
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
KUL-7211 racemateCat No HY-19673A
KUL-7211 racemate is the racemate of KUL-7211KUL-7211 is a selective agonistβ-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-(-)-α-Methyldopa (MK-351 Methyldopa) Cat No HY-B0225
Methyldopa is an alpha-adrenergic agonist(selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-(-)-α-Methyldopa (hydrate) (MK-351 hydrate Methyldopa hydrate) Cat No HY-B0225B
L-(-)-α-Methyldopa hydrate is an alpha-adrenergicagonist (selective for α2-adrenergic receptors)psychoactive drug used as a sympatholytic orantihypertensive
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
L-(-)-α-Methyldopa hydrochloride (MK-351 hydrochloride Methyldopa hydrochloride) Cat No HY-B0225A
L-(-)-α-Methyldopa hydrochloride is analpha-adrenergic agonist (selective forα2-adrenergic receptors) psychoactive drug used asa sympatholytic or antihypertensive
Purity gt98Clinical Data LaunchedSize 500 mg
L-765314Cat No HY-101385
L-765314 is a potent and selective α1b adrenergic antagonist with s of 54 nM and 20 nMreceptor Ki
for rat and human α1b adrenergic receptorrespectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
14 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
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Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
18 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
L-771688Cat No HY-U00237
L-771688 is a highly selective α1A-Adrenoceptorantagonist with a of 043plusmn002 nMKi
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
L-Epinephrine Bitartrate ((-)-Epinephrine (+)-bitartrate
salt L-Adrenaline (+)-bitartrate salt) Cat No HY-B0447A
L-Epinephrine bitartrate is an andα-adrenergic receptor agonist L-Epinephrine is aβ-adrenergic
hormone secreted by the medulla of the adrenalglands
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
L755507Cat No HY-19334
L755507 is a potent selective agonist of β -AR3
with an of 35 nMIC50
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
Labetalol hydrochloride (AH-5158 hydrochloride Sch-15719W) Cat No HY-B1108
Labetalol hydrochloride is a mixed alphabetaadrenergic antagonist that is used to treat highblood pressure
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Landiolol hydrochloride (ONO1101 hydrochloride) Cat No HY-100607A
Landiolol hydrochloride (ONO1101 hydrochloride) isa highly beta1 selective ultra-short acting
-blocker (β1β2 selectivity=2551 abetahalf-life of 4min) acts as an adrenoceptorantagonist
Purity 9996Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg
Latrepirdine dihydrochloride (Dimebolin dihydrochloride) Cat No HY-14537
Latrepirdine dihydrochloride is a neuroactivecompound with antagonist activity athistaminergic α-adrenergic and serotonergicreceptors Latrepirdine stimulates amyloidprecursor protein (APP) catabolism and
( ) secretionamyloid-β Aβ
Purity 9975Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg 200 mg
Levalbuterol ((R)-Albuterol (R)-Salbutamol Levosalbutamol) Cat No HY-B1675
Levalbuterol ((R)-Albuterol (R)-Salbutamol) is ashort-acting agonistβ2-adrenergic receptorand the active (R)-enantiomer of SalbutamolLevalbuterol is a more potent bronchodilator thanSalbutamol and has the potential for the treatmentof COPDltbrgt
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Levalbuterol tartrate (Levosalbutamol tartrate) Cat No HY-17457
Levosalbutamol tartrate(levalbuterol) is theR-enantiomer of the short-acting β2-adrenergicreceptor agonist salbutamol IC50 Value Targetβ2-adrenergic receptor Levosalbutamol andsalbutamol produced significantly betterbronchodilator responses than placebo
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Levobetaxolol hydrochloride ((S)-Betaxolol hydrochloride AL-1577A) Cat No HY-B0381B
Levobetaxolol hydrochloride is a beta-adrenergicreceptor inhibitor (beta blocker) used to lowerthe pressure in the eye in treating conditionssuch as glaucoma
Purity 9811Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Lidanserin (ZK-33839) Cat No HY-101815
Lidanserin (ZK-33839) acts as a and5-HT2A
antagonistα -adrenergic receptor1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
wwwMedChemExpresscom 15
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
16 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
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NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
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RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
LofexidineCat No HY-B1052A
Lofexidine is a selective agonistα2-receptorcommonly used to alleviate the physical symptomsof heroin and other types of opioid withdrawal
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Lofexidine hydrochloride (Baq-168 MDL-14042) Cat No HY-B1052
Lofexidine (hydrochloride) is a selective agonist commonly used to alleviateα2-receptor
the physical symptoms of heroin and other types ofopioid withdrawal
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Lusaperidone (R107474) Cat No HY-U00117
Lusaperidone (R107474) is an α2 adrenergic antagonist with s of 013 and 015 nMreceptor Ki
for α2A and α2C respectively
Purity 9774Clinical Data No Development ReportedSize 5 mg 10 mg 20 mg
LY377604Cat No HY-13713
LY377604 is a human β -adrenergic receptor3
agonist with an of 24 nM and also a -EC50 β1
and - antagonistβ2 adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine D6 HydrochlorideCat No HY-A0078S
Mebeverine D6 Hydrochloride is the deuteriumlabeled Mebeverine which is an antimuscarinic
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mebeverine metabolite O-desmethyl Mebeverine alcohol (O-desmethyl Mebeverine alcohol) Cat No HY-G0008
Mebeverine metabolite O-desmethyl Mebeverinealcohol is a metabolite of Mebeverine which is apotent inhibitor causing relaxationα1 repectorof the gastrointestinal tract
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
MedetomidineCat No HY-17034
Medetomidine(Domtor) is a potent highly selectiveα2-adrenoceptor agonist (Ki values are 108 and1750 nM for α2- and α1-adrenoceptorsrespectively)
Purity 9997Clinical Data LaunchedSize 5 mg 10 mg 50 mg
Medetomidine hydrochloride (MPV785) Cat No HY-17034B
Medetomidine hydrochloride is an agonist ofadrenergic alpha-2 receptor which is used inveterinary medicine for its analgesic and sedativeproperties
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Metaproterenol (Orciprenaline) Cat No HY-B1276A
Metaproterenol (Orciprenaline) is a direct-actingsympathomimetic and a β2-adrenergic receptor (β2AR)agonist with an of 68 nM MetaproterenolIC50
also has anti-inflammatory activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Metaproterenol hemisulfate (Orciprenaline hemisulfate) Cat No HY-B1276
Metaproterenol hemisulfate (Orciprenalinehemisulfate) is a direct-acting sympathomimeticand a agonist withβ2-adrenergic receptor (β2AR) an of 68 nM Metaproterenol hemisulfate alsoIC50
has anti-inflammatory activity
Purity 9986Clinical Data No Development ReportedSize 10 mM times 1 mL 50 mg 100 mg
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Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
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NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Metipranolol hydrochlorideCat No HY-16316
Metipranolol hydrochloride is a non-selective β blocking agentadrenergic receptor
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 25 mg 50 mg 100 mg
MetoprololCat No HY-17503
Metoprolol (Toprol) is a selective β1 receptorblocker used in treatment of several diseases ofthe cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Metoprolol SuccinateCat No HY-17503A
Metoprolol Succinate (Toprol XL) is a selective β1receptor blocker used in treatment of severaldiseases of the cardiovascular system especiallyhypertension IC50 value Target β1 receptor
Purity 9954Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
Metoprolol TartrateCat No HY-17503B
Metoprolol is a cardioselective β1-adrenergicblocking agent Target β1- adrenergic ReceptorPatients took 50 mg metoprolol twice daily withweekly titration to response or 200 mg twicedaily
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
MG 1Cat No HY-U00110
MG 1 is an α1 antagonistadrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Midaglizole hydrochloride ((plusmn)-DG5128 DG5128) Cat No HY-U00165
Midaglizole hydrochloride (DG5128) is apreferential antagonistα2-adrenoceptorMidaglizole hydrochloride (DG5128) exhibits 74times higher affinity ( =628) towardpKi
α2-adrenoceptor than α1-adrenoceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Mirabegron (YM178) Cat No HY-14773
Mirabegron is a selective β -adrenoceptor3
agonist with of 224 nMEC50
Purity 9908Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Moxisylyte hydrochloride (Thymoxamine hydrochloride) Cat No HY-B1435
Moxisylyte (hydrochloride) is (alpha 1-blocker)antagonist it can vasodilates cerebral vesselswithout reducing blood pressure It is also usedlocally in the eye to reverse the mydriasis causedby phenylephrine and other sympathomimetic agents
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 1 g
Nadolol (SQ-11725) Cat No HY-B0804
Nadolol (SQ-11725) is a non-selective and orallyactive blocker and is aβ-adrenergic receptorssubstrate of organic anion transportingpolypeptide 1A2 (OATP1A2) Nadolol has the thepotential for high blood pressure angina pectorisand vascular headaches research
Purity gt98Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 250 mg 500 mg
Nadolol D9 (SQ-11725 D9) Cat No HY-B0804S
Nadolol D9 (SQ-11725 D9) is the deuterium labeledNadolol Nadolol is a non-selective and orallyactive blockerβ-adrenergic receptors
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 17
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
18 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
20 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Naftopidil (KT-611 BM-15275) Cat No HY-B0391
Naftopidil (Flivas) a selective α1-adrenergicreceptor antagonist or alpha blocker is anantihypertensive drug
Purity 9883Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
NaminterolCat No HY-101822
Naminterol is a phenethanolamine derivative is a agonist with bronchodilatoryβ adrenoceptor2
properties Naminterol is used for treatment ofasthma
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Naphazoline hydrochlorideCat No HY-B0446
Naphazoline hydrochloride is an ocularvasoconstrictor and imidazoline derivativesympathomimetic amine Target Adrenergic ReceptorNaphazoline hydrochloride is the common name for2-(1-naphthylmethyl)-2-imidazoline hydrochloride
Purity 9856Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g 10 g
Nebivolol (R 065824) Cat No HY-B0203
Nebivolol selectively inhibits β1- adrenergicreceptor with IC50 of 08 nM Target β1-adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Nebivolol hydrochloride (R 065824 hydrochloride) Cat No HY-B0203A
Nebivolol hydrochloride selectively inhibits β1-adrenergic receptor with IC50 of 08 nM Targetβ1- adrenergic receptor Nebivolol reduces cellproliferation of human coronary smooth musclecells (haCSMCs) and endothelial cells (haECs) in aconcentration- and time-dependent maner
Purity 9873Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 500 mg
Nefazodone hydrochloride (BMY-13754 MJ-13754-1) Cat No HY-B1396
Nefazodone hydrochloride is an antidepressantdrug
Purity 9971Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
NicergolineCat No HY-B0702
Nicergoline is an ergot derivative used to treatsenile dementia and other disorders with vascularorigins Target Alpha-1A adrenergic receptorNicergoline acts by inhibiting the postsynapticalpha(1)-adrenoceptors on vascular smooth muscle
Purity 9906Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Norepinephrine (Levarterenol L-Noradrenaline) Cat No HY-13715
Norepinephrine (Levarterenol L-Noradrenaline) isa -selective agonist withβ1 adrenergic receptor
of 537 μMEC50
Purity 9808Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Norepinephrine bitartrate monohydrate (Levarterenol
bitartrate monohydrate hellip) Cat No HY-13715B
Norepinephrine bitartrate monohydrate(Levarterenol bitartrate monohydrateL-Noradrenaline bitartrate monohydrate) is a
-selective agonist withβ1 adrenergic receptor of 537 μMEC50
Purity 9975Clinical Data LaunchedSize 500 mg 1 g 5 g
Norepinephrine hydrochloride (Levarterenol hydrochloride
L-Noradrenaline hydrochloride) Cat No HY-13715A
Norepinephrine hydrochloride (Levarterenolhydrochloride) is a -selective β1 adrenergic
agonist with of 537 μMreceptor EC50
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
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NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
NRA-0160Cat No HY-101641
NRA-0160 is a selective dopamine D4 receptorantagonist with a value of 048 nM and withKi
negligible affinity for dopamine D2 receptor( gt10000 nM) ( 39 nM) ratKi D3 receptor Ki
( 180 nM) and rat 5-HT2A receptor Ki α1 ( 237 nM)adrenoceptor Ki
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Octopamine hydrochloride ((plusmn)-p-Octopamine hydrochlorid) Cat No HY-B0528A
Octopamine hydrochloride ((plusmn)-p-Octopaminehydrochlorid) is an endogenous biogenic amine thatis closely related to norepinephrine and haseffects on the adrenergic and dopaminergicsystems
Purity gt990Clinical Data No Development ReportedSize 10 mM times 1 mL 500 mg 1 g 5 g
Olanzapine (LY170053) Cat No HY-14541
Olanzapine (LY170053) is a selective monoaminergicantagonist with high affinity binding to serotonin
( =7 4 11 57 and 5H1 5HT2A2C 5HT3 5HT6 Ki
nM respectively) ( =11 to 31dopamine D1-4 Ki
nM) ( =19-25 nM) andmuscarinic M1-5 Ki
( =19 nM)adrenergic α1 receptor Ki
Purity 9994Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Olanzapine D3 (LY170053 D3) Cat No HY-14541S
Olanzapine D3 (LY170053 D3) is the deuteriumlabeled Olanzapine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
OPC-28326Cat No HY-101610
OPC-28326 is a selective peripheral vasodilatorand an angatonist of withα2-adrenergic receptor
of 2040 285 and 55nM for α2A- α2B- andKi
α2C-adrenoceptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Oxprenolol hydrochloride (Ba 39089) Cat No HY-B1486
Oxprenolol hydrochloride (Ba 39089) is an orallybioavailable receptor ( )β-adrenergic β-ARantagonist with a of 710 nM in a radioligandKi
binding assay using rat heart muscle
Purity 9986Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Paliperidone (9-Hydroxyrisperidone) Cat No HY-A0019
Paliperidone (9-Hydroxyrisperidone) the majoractive metabolite of Risperidone is a dopamine
antagonist and antagonistD2 5-HT2APaliperidone is also active as an antagonist at
and receptors andα1 α2 adrenergic receptorsH1-histaminergic
Purity 9987Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
PamatololCat No HY-U00019
Pamatolol is a cardioselective beta-adrenoceptorantagonist without sympathomimetic activity
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pardoprunox (SLV-308 DU-126891) Cat No HY-14958
Pardoprunox (SLV-308) is a partial dopamine D2and partial agonist and a D3 receptor serotonin
agonist with s of 8 925-HT1A receptor pEC50
and 63 respectively
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
Pardoprunox hydrochloride (SLV-308 hydrochloride DU-126891 hydrochloride) Cat No HY-14958A
Pardoprunox (SLV-308) hydrochloride is a partial and partial agonistdopamine D2 D3 receptor
and a agonist withserotonin 5-HT1A receptors of 8 92 and 63 respectivelypEC50
Purity 9824Clinical Data Phase 3Size 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
wwwMedChemExpresscom 19
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
20 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Pargolol hydrochloride (Ko 1400 hydrochloride) Cat No HY-101658
Pargolol hydrochloride is a β adrenergic antagonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Penbutolol sulfate ((-)-Terbuclomine) Cat No HY-B1154
Penbutolol sulfate is able to bind to both beta-1adrenergic receptors and beta-2 adrenergicreceptors (the two subtypes) thus making it anon-selective β blocker Penbutolol is asympathomimetic drugused in the treatment of highblood pressure
Purity 9962Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
PerphenazineCat No HY-A0077
Perphenazine is a typical antipsychotic druginhibits 5-HT receptor Alpha-1A adrenergic2A
receptor Dopamine receptor D2D3 D2L receptorand with values ofHistamine H1 receptor Ki
56 10 0765013 34 and 8 nM respectively
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Perphenazine D8 DihydrochlorideCat No HY-A0077AS
Perphenazine D8 Dihydrochloride is the deuteriumlabeled Perphenazine which is a typicalantipsychotic drug(5-HT Dopamine receptorligand)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PF-610355Cat No HY-14296
PF-610355 is a long-acting inhaled agonist with an ofβ -adrenoreceptor2 EC50
026 nM PF-610355 has the potential for the studyof asthma and COPD
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Phenoxybenzamine hydrochlorideCat No HY-B0431A
Phenoxybenzamine hydrochloride is a selectiveantagonist of both andα-adrenoceptor
that is commonly used for thecalmodulintreatment of hypertension specifically caused bypheochromocytoma
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 200 mg 500 mg 1 g
Phentolamine mesylate (Phentolamine methanesulfonate) Cat No HY-B0362A
Phentolamine mesylate is a competitive reversible antagonist with an between 5α-adrenoceptor IC50
and 30 nM
Purity 9983Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylephrine ((R)-(-)-Phenylephrine L-Phenylephrine) Cat No HY-B0769
(R)-(-)-Phenylephrine is a selective agonist primarily used as aα -adrenoceptor1
decongestant
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Phenylephrine hydrochloride ((R)-(-)-Phenylephrine
hydrochloride L-Phenylephrine hydrochloride) Cat No HY-B0471
(R)-(-)-Phenylephrine hydrochloride is a selective agonist with of 586 487α -adrenoceptor1 pK si
and 470 for α α and α receptors1D 1B 1A
respectively
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Phenylethanolamine ACat No HY-131103
Phenylethanolamine A acts as a β-adrenergicagonist Phenylethanolamine A is a byproductduring the Ractopamine synthesis process
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
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Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Phenylethanolamine A-D3Cat No HY-131103S
Phenylethanolamine A-D3 is a deuterium labeledPhenylethanolamine A Phenylethanolamine A acts asa β-adrenergic agonist Phenylethanolamine A is abyproduct during the Ractopamine synthesisprocess
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Pimozide (R6238) Cat No HY-12987
Pimozide is a antagonistdopamine receptorwith s of 14 nM 25 nM and 588 nM for dopamineKi
D2 D3 and D1 receptors respectively and alsohas affinity at with a of 39α1-adrenoceptor Ki
nM Pimozide also inhibits and STAT3 STAT5
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Pimozide D4 (R6238 D4) Cat No HY-12987S
Pimozide D4 (R6238 D4) is a deuterium labeledPimozide
Purity gt98Clinical Data Phase 4Size 1 mg 5 mg
Pindolol (LB-46) Cat No HY-B0982
Pindolol (LB-46) is a nonselective β-blocker withpartial beta-adrenergic receptor agonist activityalso functions as a 5-HT1A receptor weak partialantagonist (Ki=33nM)
Purity 9991Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Piperoxan hydrochloride (Benodaine hydrochloride) Cat No HY-100850
Piperoxan hydrochloride is an α adrenoceptor2
antagonist
Purity 9939Clinical Data No Development ReportedSize 10 mM times 1 mL 2 mg 5 mg 10 mg 25 mg 50 mg 100 mg
PiribedilCat No HY-12707
Piribedil is a ( )dopamine D receptor2 D R2
agonist which also displays antagonist property at ( )hα -adrenoceptor1A hα -AR1A
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg 500 mg
Piribedil D8 (ET-495 D8) Cat No HY-12707S
Piribedil D8 is the deuterium labeled Piribedilwhich is an antiparkinsonian agent
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
PrazosinCat No HY-B0193
Prazosin is an alpha-adrenergic blocker and is asympatholytic drug used to treat high bloodpressure and anxiety PTSD and panic disorderTarget Adrenergic Receptor Prazosin is asympatholytic drug used to treat high bloodpressure and anxiety PTSD andpanic disorder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Prazosin hydrochlorideCat No HY-B0193A
Prazosin hydrochloride is an alpha-adrenergicblocker and is a sympatholytic drug used to treathigh blood pressure and anxiety PTSD and panicdisorder
Purity 9973Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 200 mg 500 mg
Pronethalol ((plusmn)-Pronethalo) Cat No HY-B1238
Pronethalol is a non-selective beta-adrenergicblocking agent protect against and to reverseDigitalis-induced ventricular arrhythmias Targetbeta-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 21
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
PropranololCat No HY-B0573B
Propranolol is a nonselective β-adrenergic receptor antagonist has high affinity for the β1AR(βAR)
and β2AR with values of 18 nM and 08 nMKi
respectively Propranolol inhibits [ H]-DHA3
binding to rat brain membrane preparation with an of 12 nMIC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol D7 hydrochlorideCat No HY-B0573S
Propranolol D7 hydrochloride is a deuteriumlabeled Propranolol hydrochloride Propranololhydrochloride is a nonselective β-adrenergic
antagonist has high affinity forreceptor (βAR)the β1AR and β2AR with values of 18 nM and 08Ki
nM respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Propranolol hydrochlorideCat No HY-B0573
Propranolol hydrochloride is a nonselective antagonist has highβ-adrenergic receptor (βAR)
affinity for the β1AR and β2AR with values ofKi
18 nM and 08 nM respectively
Purity 9979Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg 1 g
QF0301BCat No HY-101690
QF0301B is an antagonistα1 adrenergic receptorand a low α2 adrenoceptor 5-HT2A and histamineH1 receptor blocker
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rauwolscine hydrochloride (α-Yohimbine hydrochloride
Corynanthidine hydrochloride Isoyohimbine hydrochloride) Cat No HY-12710A
Rauwolscine hydrochloride is a potent and specific receptor antagonist with a of 12α2 adrenergic Ki
nM
Purity 9995Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg
Ritanserin (R 55667) Cat No HY-10791
Ritanserin (R 55667) is a highly potentrelatively selective orally active long actingantagonist of with an of5-HT receptor2 IC50
09 nM less active on Histamine H Dopamine1
D Adrenergic α Adrenergic α receptors2 1 2
Purity gt990Clinical Data Phase 2Size 10 mM times 1 mL 5 mg
Ritodrine hydrochloride (DU21220 hydrochloride) Cat No HY-B0452
Ritodrine hydrochloride (DU21220 hydrochloride) isa β-2 adrenergic receptor agonist Target β-2Adrenergic Receptor Ritodrine is a tocolytic drugused to stop premature labor
Purity 9901Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Ro 363Cat No HY-123268
Ro 363 is a potent and highly selective agonist RO 363 is an effectiveβ1-adrenoceptor
inotropic stimulant and is a cardiovascularmodulator that reduces diastolic blood pressureand pronounces increases in myocardialcontractility
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Rotigotine (N-0437 N-0923) Cat No HY-75502
Rotigotine (N-0437 N-0923) is a full agonist of a partial agonist of thedopamine receptor
and an antagonist of the5-HT1A receptor with s of 071nMα2B-adrenergic receptor Ki
4-15nM and 83nM for the dopamine D3 receptorand D2 D5 D4 receptors and dopaminehellip
Purity 9998Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Rotigotine Hydrochloride (N-0923 Hydrochloride) Cat No HY-A0007
Rotigotine Hydrochloride (N-0923 Hydrochloride) isa full agonist of a partialdopamine receptoragonist of the and an5-HT1A receptorantagonist of the with α2B-adrenergic receptor Ki
of 071nM 4-15nM and 83nM for the dopamine D3receptor and D2 D5 D4 receptors and dopaminehellip
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg
22 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
RS 17053 hydrochloride (RS-17053) Cat No HY-101336
RS 17053 hydrochloride is a potent and selective antagonist with a valueα1 adrenoceptorA pKi
of 91 in native cell membrane and a valuepA2
of 98 in functional assays
Purity 9925Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salbutamol (Albuterol AH-3365) Cat No HY-B1037
Salbutamol is a short-acting β2-adrenergicreceptor agonist used for the relief ofbronchospasm in conditions such as asthma andchronic obstructive pulmonary disease (COPD)
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Salbutamol hemisulfate (Albuterol hemisulfate AH-3365 hemisulfate) Cat No HY-B0436
Salbutamol Hemisulfate (Albuterol hemisulfate) isa short-acting β2 adrenergic receptor agonistTarget β2 Adrenergic Receptor SalbutamolHemisulfate (Albuterol hemisulfate) is ashort-acting selective beta2-adrenergic receptoragonist used in the treatment of asthma andhellip
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Salmeterol (GR33343X) Cat No HY-14302
Salmeterol is a long-acting beta2-adrenergicreceptor (beta 2AR) agonist used clinically totreat asthma
Purity 9968Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Salmeterol xinafoate (GR 33343X xinafoate) Cat No HY-17453
Salmeterol xinafoate is a long-acting beta-2adrenergic receptor ( ) agonist with ofβ AR2 Ki
15 nM for WT β AR and used for asthma2
treatment
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg 200 mg
Salmeterol-D3Cat No HY-135119
Salmeterol-D3 is the deuterium labeled Salmeterol(HY-14302) Salmeterol is a long-acting
agonist that is used forbeta2-adrenergic receptorthe study of asthma and chronic obstructivepulmonary disease (COPD)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine (67-Epoxytropine) Cat No HY-B0459
Scopine is the metabolite of anisodine which is aα1-adrenergic receptor agonist and used in thetreatment of acute circulatory shock
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Scopine hydrochloride (67-Epoxytropine hydrochloride) Cat No HY-B0459A
Scopine hydrochloride (67-Epoxytropinehydrochloride) is the metabolite of anisodinewhich is a α1-adrenergic receptor agonist and usedin the treatment of acute circulatory shock
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Sertindole (Lu 23-174) Cat No HY-14543
Sertindole a neuroleptic is one of the newerantipsychotic medications available TargetMulti-target In vitro studies showed thatsertindole exerts a potent antagonism at serotonin5-HT2A 5-HT2C dopamine D2 and αl adrenergicreceptors
Purity 9976Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg
Setiptiline (Org-8282) Cat No HY-32329
Setiptiline (Org-8282) is a serotonin receptorantagonist Setiptiline is a tetracyclicantidepressant (TeCA) which acts as anoradrenergic and specific serotonergicantidepressant (NaSSA)
Purity 9654Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg 200 mg
wwwMedChemExpresscom 23
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Silodosin (KAD 3213 KMD 3213) Cat No HY-10122
Silodosin (KAD 3213 KMD 3213) is a potentselective and orally active α1A-adrenergic receptor
blocker(α1A-AR)
Purity 9996Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Solabegron (GW 427353) Cat No HY-19436
Solabegron (GW 427353) is a selective agonist stimulating cAMPβ -adrenergic receptor3
accumulation in Chinese hamster ovary cellsexpressing the human β -AR with an value3 EC50
of 22 nM
Purity 9991Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
Sotalol D6 hydrochlorideCat No HY-B0437AS
Sotalol D6 hydrochloride is a deuterium labeledSotalol hydrochloride Sotalol hydrochloride is anon-selective competitive β-adrenergic receptorantagonist that also exhibits Class IIIantiarrhythmic properties by its inhibition of
potassium channels
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Sotalol hydrochloride (MJ 1999) Cat No HY-B0437
Sotalol hydrochloride (MJ 1999) is a non-selectivecompetitive antagonist thatβ-adrenergic receptoralso exhibits Class III antiarrhythmic propertiesby its inhibition of potassium channels
Purity 9977Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 200 mg 500 mg 1 g
Spirendolol (Li 32-468 S 32-468 Substance 32468) Cat No HY-101817
Spirendolol is a β adrenergic receptorantagonist
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
SR59230ACat No HY-100672
SR59230A is a potent selective and blood-brainbarrier penetrating β3-adrenergic receptorantagonist with s of 40 408 and 648 nM forIC50
β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 5 mg 10 mg 50 mg
SR59230A hydrochlorideCat No HY-103200
SR59230A hydrochloride is a potent selective andblood-brain barrier penetrating β3-adrenergic
antagonist with s of 40 408 andreceptor IC50
648 nM for β3 β1 and β2 receptors respectively
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Synephrine (Oxedrine) Cat No HY-N0132
Synephrine (Oxedrine) is an andα-adrenergic agonist derived from the β-adrenergic Citrus
it has sympathomimetic andaurantiumstructural similarities to ephedra and ephedrinealkaloids
Purity gt98Clinical Data No Development ReportedSize 5 mg
Synephrine hydrochloride (Oxedrine hydrochloride) Cat No HY-N0132A
Synephrine hydrochloride (Oxedrine hydrochloride)is an and agonist derivedα-adrenergic β-adrenergicfrom the it hasCitrus aurantiumsympathomimetic and structural similarities toephedra and ephedrine alkaloids
Purity 9983Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Talipexole dihydrochloride (B-HT 920 dihydrochloride) Cat No HY-A0008
Talipexole dihydrochloride (B-HT 920dihydrochloride) is a dopamine D2 receptoragonist α2-adrenoceptor agonist and 5-HT3receptor antagonist which displaysantiParkinsonian activity
Purity 9999Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
24 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
TamsulosinCat No HY-B0661
Tamsulosin is a selective α1 receptor antagonistTarget α1 receptor Tamsulosin is a selective α1receptor antagonist that has preferentialselectivity for the α1A receptor in the prostateversus the α1B receptor in the blood vessels
Purity 9962Clinical Data LaunchedSize 10 mg 50 mg 100 mg
Tamsulosin hydrochloride ((R)-(-)-YM12617 LY253351) Cat No HY-B0661A
Tamsulosin hydrochloride((R)-(-)-YM12617LY253351)is a selective α1 receptor antagonist Target α1receptor Tamsulosin is a selective α1 receptorantagonist that has preferential selectivity forthe α1A receptor in the prostate versus the α1Breceptor in the blood vessels
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
TD-5471 hydrochlorideCat No HY-19942A
TD-5471 hydrochloride is a potent and selectivefull agonist of the human β -adrenoceptor2
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) Cat No HY-101755
Tedatioxetine hydrobromide acts as a triplereuptake inhibitor and 5-HT2A 5-HT2C 5-HT3
and antagonistα -adrenergic receptor1A
Purity 9844Clinical Data Phase 2Size 1 mg 5 mg
TeoprololCat No HY-U00016
Teoprolol is a blockerβ-adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TerazosinCat No HY-B0371
Terazosin is a quinazoline derivative and acompetitive and orally active α1-adrenoceptorantagonist Terazosin works by relaxing bloodvessels and the opening of the bladder Terazosinhas the potential for benign prostatic hyperplasia(BPH) and high blood pressure treatment
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochlorideCat No HY-B0371F
Terazosin hydrochloride is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride works by relaxing blood vessels andthe opening of the bladder
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Terazosin hydrochloride dihydrateCat No HY-B0371A
Terazosin hydrochloride dihydrate is a quinazolinederivative and a competitive and orally active
antagonist Terazosinα1-adrenoceptorhydrochloride dihydrate works by relaxing bloodvessels and the opening of the bladder
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 100 mg
Terbutaline sulfate (Terbutaline hemisulfate) Cat No HY-B0802
Terbutaline sulfate is a β2-adrenergic receptoragonist a fast-acting bronchodilator and atocolytic to delay premature labor
Purity gt980Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Tertatolol ((plusmn)-Tertatolol Racemic Tertatolol dl-Tertatolol) Cat No HY-U00356
Tertatolol is a potent antagonist of and withbeta-adrenoceptor 5-HT receptor
unique renal vasodilatatory effects
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 25
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
TetrahydroalstonineCat No HY-N1163
Tetrahydroalstonine a indole alkaloid isolatedfrom the fruits of is a selectiveRhazya stricta
antagonistalpha 2-adrenoceptor
Purity 9995Clinical Data No Development ReportedSize 1 mg 5 mg
Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride) Cat No HY-B0556A
Tetrahydrozoline (hydrochloride) is aα-adrenoceptor agonist Target α-adrenoceptorahydrozoline is an imidazoline derivative withalpha receptor agonist activity widely availablein over-the-counter topical ocular and nasalformulations
Purity 9990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg
Tiodazosin (BL-5111) Cat No HY-100255
Tiodazosin is a potent competitive postsynaptic antagonistalpha adrenergic receptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
TizanidineCat No HY-B0194
Tizanidine is an α2-adrenergic receptor agonistand inhibits neurotransmitter release from CNSnoradrenergic neurons Target α2-adrenergicreceptor Tizanidine is a drug that is used as amuscle relaxant It is a centrally acting α2adrenergic agonist
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tizanidine hydrochlorideCat No HY-B0194A
Tizanidine hydrochloride is an α2-adrenergicreceptor agonist and inhibits neurotransmitterrelease from CNS noradrenergic neurons Targetα2-adrenergic receptor Tizanidine is a drug thatis used as a muscle relaxant It is a centrallyacting α2 adrenergic agonist
Purity 9948Clinical Data LaunchedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Todralazine (Ecarazine) Cat No HY-B1001
Todralazine (Ecarazine) is an anti-hypertensiveagent acts as a blocker with antioxidantβ AR2
and free radical scavenging activity
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Todralazine hydrochloride (Ecarazine hydrochloride) Cat No HY-B1001A
Todralazine hydrochloride (Ecarazinehydrochloride) is an anti-hypertensive agent actsas a blocker with antioxidant and freeβ AR2
radical scavenging activity
Purity 9817Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg 100 mg
Tolazoline (Imidaline NSC35110) Cat No HY-A0066
Tolazoline(Imidaline) is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt98Clinical Data No Development ReportedSize 500 mg
Tolazoline hydrochloride (Imidaline hydrochloride NSC35110 hydrochloride) Cat No HY-A0066A
Tolazoline (hydrochloride)(Imidaline(hydrochloride)) Hcl is a non-selectivecompetitive α-adrenergic receptor antagonist
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g 5 g
Trifluoperazine D8Cat No HY-B0532S
Trifluoperazine D8 is a deuterium labeledTrifluoperazine Trifluoperazine is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptoris also a potent dopamine D2 receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
26 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Trifluoperazine dihydrochloride (TFP SKF5019) Cat No HY-B0532A
Trifluoperazine dihydrochloride (TFP) is anantipsychotic phenothiazine agent and a selective
antagonist Trifluoperazineα1-adrenergic receptordihydrochloride is also a potent dopamine D2
inhibitorreceptor
Purity gt990Clinical Data LaunchedSize 10 mM times 1 mL 100 mg 500 mg
Tropodifene (Tropaphen) Cat No HY-U00313
Tropodifene (Tropaphen) is an α-Adrenergic receptorinhibitor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Tulobuterol (C-78 free base) Cat No HY-B1810
Tulobuterol (C-78 free base) is a long-acting agonist which reduces theβ -adrenoceptor2
frequency of exacerbations of chronic obstructivepulmonary disease and bronchial asthma
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Tulobuterol hydrochloride (C-78) Cat No HY-W011733
Tulobuterol hydrochloride (C-78) is a long-actingβ -adrenoceptor2 agonist which reduces thefrequency of exacerbations of chronic obstructive
pulmonary disease and bronchial asthma
Purity 9982Clinical Data LaunchedSize 10 mM times 1 mL 50 mg 100 mg 500 mg
Ulimorelin (TZP-101) Cat No HY-14903
Ulimorelin (TZP-101) is a ghrelin receptor (GRLN)agonist with an of 29 nM and a of 16 nMEC50 Ki
Ulimorelin is a prokinetic agent and causesvasorelaxation through competitive antagonistaction at Ulimorelin stimulatesα1-adrenoceptorsintestinal motility and is used for malnutrition
Purity gt98Clinical Data Phase 3Size 1 mg 5 mg
UrapidilCat No HY-B0716
Urapidil is an antagonist andα1 adrenoreceptora agonist5-HT receptor1A
Purity 9989Clinical Data LaunchedSize 10 mM times 1 mL 50 mg
Urapidil D6Cat No HY-B0716S
Urapidil D6 is a deuterium labeled UrapidilUrapidil is an antagonist and aα1-adrenoreceptor
agonist5-HT receptor1A
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Urapidil hydrochlorideCat No HY-B0354A
Urapidil HCl is an α1-adrenoceptor antagonist and5-HT1A receptor agonist
Purity gt990Clinical Data LaunchedSize 5 mg 10 mg 25 mg
Vanilpyruvic acid (Vanylpyruvic acid) Cat No HY-101416
Vanilpyruvic acid is a catecholamine metaboliteand precursor to vanillactic acid
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg
Vatinoxan hydrochloride (MK-467 hydrochloride L-659066 hydrochloride) Cat No HY-19057A
Vatinoxan hydrochloride (MK-467hydrochlorideL-659066 hydrochloride) is aperipheral antagonistα2 adrenergic receptor
Purity 9928Clinical Data No Development ReportedSize 10 mM times 1 mL 5 mg 10 mg 25 mg
wwwMedChemExpresscom 27
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Vilanterol (GW642444) Cat No HY-14300
Vilanterol (GW642444) is a long-acting (β -AR) agonist with 24 hβ -adrenoceptor2 2
activity The s for β -ARβ -AR andpEC50 2 1
β -AR is 1037plusmn005 698plusmn003 and 736plusmn0033
respectively
Purity gt98Clinical Data LaunchedSize 1 mg 5 mg
Vilanterol trifenatate (GW642444 trifenatate) Cat No HY-14300A
Vilanterol trifenatate (GW642444 trifenatate) is along-acting (β -AR) agonistβ -adrenoceptor2 2
with inherent 24-hour activity The s forpEC50
β -AR β -AR and β -AR are 1037 698 and2 1 3
736 respectively
Purity 9902Clinical Data LaunchedSize 10 mM times 1 mL 5 mg 10 mg 50 mg 100 mg
Xylazine (BAY 1470) Cat No HY-B0443
Xylazine (BAY 1470) is a strong α2-adrenergicagonist whose effects are mediated via stimulationof central α2-receptors Xylazine hydrochloride isused as a sedative analgesic and muscle relaxantin veterinary medicine
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
Xylazine hydrochloride (BAY 1470 hydrochloride) Cat No HY-B0443A
Xylazine hydrochloride (BAY 1470 hydrochloride) isa strong agonist whose effects areα2-adrenergicmediated via stimulation of central α2-receptorsXylazine hydrochloride is used as a sedativeanalgesic and muscle relaxant in veterinarymedicine
Purity 9990Clinical Data No Development ReportedSize 10 mM times 1 mL 100 mg 500 mg
Xylometazoline hydrochlorideCat No HY-B0475
Xylometazoline hydrochloride is an α-adrenoceptoragonist commonly used as nasal decongestant
Purity 9988Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YohimbineCat No HY-12715
Yohimbine is a potent and relatively nonselectivealpha 2-adrenergic receptor (AR) antagonist withIC50 of 06 μM
Purity gt98Clinical Data Phase 4Size 500 mg
Yohimbine HydrochlorideCat No HY-N0127
Yohimbine Hydrochloride is an alpha2-adrenoreceptor antagonist blocking the pre- andpostsynaptic alpha-2 adrenoreceptors and causingan increased release of noradrenaline anddopamine
Purity 9985Clinical Data LaunchedSize 10 mM times 1 mL 500 mg 1 g
YS-49Cat No HY-15477
YS-49 is a (a downstream target of RhoA)PI3KAktactivator to reduce RhoAPTEN activation in the3-methylcholanthrene-treated cells YS-49 inhibits
-stimulated proliferationangiotensin II (Ang II)of VSMCs via induction of heme oxygenase (HO)-1
Purity 9538Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
YS-49 monohydrateCat No HY-15477A
YS-49 (monohydrate) is a (a downstreamPI3KAkttarget of RhoA) activator to reduce RhoAPTENactivation in the 3-methylcholanthrene-treatedcells YS-49 inhibits angiotensin II (Ang
-stimulated proliferation of VSMCs viaII)induction of heme oxygenase (HO)-1
Purity gt980Clinical Data No Development ReportedSize 10 mM times 1 mL 10 mg 50 mg
Zilpaterol-d7Cat No HY-A0072S
Zilpaterol-d7 is a deuterium labeled Zilpaterol
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
28 Tel 609-228-6898 Fax 609-228-5909 Email salesMedChemExpresscom
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29
Zinterol (MJ 9184) Cat No HY-14304
Zinterol (MJ 9184) is a potent and selective agonist Zinterol increases I inβ2-adrenoceptor Ca
a concentration-dependent manner with an EC of50
22 nM
Purity gt98Clinical Data No Development ReportedSize 10 mM times 1 mL 1 mg 5 mg 10 mg
ZK-90055 hydrochlorideCat No HY-U00293
ZK-90055 hydrochloride is a β2 adrenergic agonistreceptor
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
α1 adrenoceptor-MO-1Cat No HY-U00333
α1 adrenoceptor-MO-1 an S enantiomer hasaffinity at showsalpha 1 adrenergic receptoralphalytic activity and possesses analgesicaction more active than R enantiomer
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 1Cat No HY-101514
β3-AR agonist 1 (compound 15) is a highly potentselective and orally available β3-adrenergic
agonist ( =18 nM) beingreceptor (β3-AR) EC50
inactive to β1- β2- and α1A-AR (β1β3 β2β3and α1Aβ3gt556-fold)
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
β3-AR agonist 2Cat No HY-U00391
β -AR agonist 2 is a potent and selective3
( ) agonist with anβ -adrenergic receptor3 β -AR3
of 8 nMEC50
Purity gt98Clinical Data No Development ReportedSize 1 mg 5 mg
wwwMedChemExpresscom 29