active and passive transport of plasma membrane

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The plasma membrane is a selectively permeable barrier between the cell and the extracellular environment. Its permeability properties ensure that essential molecules such as ions, glucose, amino acids, and lipids readily enter the cell, metabolic intermediates remain in the cell, and waste compounds leave the cell. Introduction; Movement of virtually all molecules and ions across cellular membranes is mediated by selective membrane transport proteins embedded in the phospholipid bilayer. Membrane transport by E.ANANTHARAJ,1 st msc ,cas in botany University of madras

description

it will give basic understanding of plasma membrane function

Transcript of active and passive transport of plasma membrane

Page 1: active and passive transport of plasma membrane

The plasma membrane is a selectively permeable barrier between the cell and the extracellular environment.

Its permeability properties ensure that essential molecules such as ions, glucose, amino acids, and lipids readily enter the cell, metabolic intermediates remain in the cell, and waste compounds leave the cell.

Introduction;

Movement of virtually all molecules and ions across cellular membranes is mediated by selective membrane transport proteins embedded in the phospholipid bilayer.

Membrane transport by E.ANANTHARAJ,1st msc ,cas in botany University of madras

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Passive transport

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Passive TransportA process that does not require energy to move molecules from a HIGH to LOW concentration

Diffusion

Facilitated Diffusion

Osmosis

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• Diffusion is the movement of small particles across a selectively permeable membrane like the cell membrane until equilibrium is reached.

These particles move from an area of high concentration to an area of low concentration.

outside of cell

inside of cell

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• Facilitated Diffusion is the movement of larger molecules like glucose through the cell membrane – larger molecules must be “helped”

Proteins in the cell membrane form channels for large molecules to pass through

Proteins that form channels (pores) are called protein channels

outside of cell

inside of cell

Glucose molecules

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• Osmosis is the diffusion of water through a selectively permeable membrane like the cell membrane

Water diffuses across a membrane from an area of high concentration to an area of low concentration.

Semi-permeable membrane is

permeable to water, but not to sugar

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Active Transport

“The Doorman”“The Doorman”

conformational change

• Cells may need to move molecules against concentration gradient– shape change transports solute from

one side of membrane to other – protein “pump”– “costs” energy = ATP

ATP

low

high

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symportantiport

Active transport• Many models & mechanisms

ATP ATP

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summeryPassive Transport

Process Energy Source Example

Simple diffusion Kinetic energyMovement of O2 through

membrane

Facilitated diffusion Kinetic energy Movement of glucose into

cells

Osmosis Kinetic energyMovement of H2O in & out

of cells

Filtration Hydrostatic pressure

Formation of kidney filtrate

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Active Transport

Process Energy Source Example

Active transport of solutes ATP Movement of ions across

membranes

Exocytosis ATP Neurotransmitter secretion

Endocytosis ATP White blood cell phagocytosis

Fluid-phase endocytosis ATP Absorption by intestinal cells

Receptor-mediated endocytosis ATP Hormone and cholesterol

uptake

Endocytosis via caveoli ATP Cholesterol regulation

Endocytosis via coatomer vesicles ATP Intracellular trafficking

of molecules

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REFERENCES

Books ;.1.Molecular cell biology 5th edition .Lodish et.al2.p.s verma &v.k agarwal

Online source;1,www.biology junction.com2,www.uma.maine.edu3,www.ocuy.org.