ACTH - jpet.aspetjournals.orgjpet.aspetjournals.org/content/jpet/125/4/local/back-matter.pdf ·...
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ABS -ALK 8136 8138 8138 8136 8136 8136 8136 8138 8136 8136 8116 8116 8116 8116 8136 8136 8136 8136 8147 8147 8147 8147 8147 8147 8113 8133 8133 8113 8133 8133 8113 8133 8133 8133 8113 8133 8133 8113 8113 8133 8113 8145 8145 8145 8129 8129 8129 8147 8147 8147 8147 8146 8146 8146 1959 SUBJECT INDEX S-l ABSORPTION dissociation constants gastrointestinal tract intestinal loops intestinal tract lipid-solubility organic compounds pH gradients tetracycline transport mechani sm unionized forms ACETAZOLAMIDE autoradiograms body fluid concentrations brain tissue distribution S35-labeled ACETOPRENETIDIN phenylquinone writhing response protective action (o-ACETOXYPHENYL) PROPIONIC ACID phenylquinone writhing response protective action N-ACETYL--AMINOPHENOL phenylquinone writhing response protective actioT ACETYLCHOLINE blood pressure neostigmine pretreatment nictitating membrane oxyphencyc limine physosti gmine pretreatment smooth muscle spinal cord reflexes ACID-BASE BALANCE mersalyl-induced diuresis protein-bound ul fhydryl changes specific renal cells ACIDOSIS cytoplasmic PBSH mersalyl-induced diuresis plasma/CSF distribution ratios specific renal cells weak electrolytes ACIDS, ORGANIC dissociation constants intestinal absorption lipid-solubility pH values unionized forms ACORUS CALAMIJS acute toxicity hypnotic potentiating action hypothermic action peripheral vascular effects pharmacological actions volatile oil ACTH anterior pituitary release human subjects intravenous injection morphine activation morphine influence nalorphine influence 8132 pituitary-adrenal system 8132 plasma hydrocortisone levels vasopressin pretreatment ADRENAL GLANDS ACTH administration 8132 ascorbic acid content 8132 human subjects hydrocortisone release hypothalamic lesions 8132 morphine 8132 morphine influence weight 8144 ADRENERGIC AGENTS 8121 atropine blockade 8144 brain transections 8144 EEC activation 8121 ADRENERGIC BLOCKADE 8144 catechol amine pressor 8121 responses dibenzyline 8141 hecylamine interactions ALCOHOL, ETHYL 8141 acorus oil 8141 chlorpromazine reserpine 8141 sleeping time 8141 ALCOHOL INTOXICATION, EXPERIMENTAL 8123 action duration 8141 heart rate 8123 megimide influence ALKALOSIS 8136 cytoplasmic PBSH 8141
Transcript of ACTH - jpet.aspetjournals.orgjpet.aspetjournals.org/content/jpet/125/4/local/back-matter.pdf ·...
ABS -ALK
8136
8138
8138
8136
81368136
81368138
8136
8136
8116
81168116
8116
8136
8136
8136
8136
8147
8147
8147
8147
8147
8147
8113
8133
8133
8113
8133
8133
8113
8133
8133
8133
811381338133
8113811381338113
8145
8145
8145
81298129
8129
81478147
8147
8147
8146
81468146
1959SUBJECT INDEX
S-l
ABSORPTION
dissociation constants
gastrointestinal tract
intestinal loops
intestinal tract
lipid-solubility
organic compounds
pH gradients
tetracycline
transport mechani sm
unionized forms
ACETAZOLAMIDE
autoradiograms
body fluid concentrations
brain tissue distribution
S35-labeled
ACETOPRENETIDIN
phenylquinone writhing
response
protective action
(o-ACETOXYPHENYL)
PROPIONIC ACID
phenylquinone writhing
response
protective action
N-ACETYL-�-AMINOPHENOL
phenylquinone writhing
response
protective actioT�
ACETYLCHOLINE
blood pressure
neostigmine pretreatment
nictitating membrane
oxyphencyc limine
physosti gmine pretreatment
smooth muscle
spinal cord reflexes
ACID-BASE BALANCE
mersalyl-induced diuresis
protein-bound �ul fhydryl
changes
specific renal cells
ACIDOSIS
cytoplasmic PBSH
mersalyl-induced diuresis
plasma/CSF distribution
ratios
specific renal cells
weak electrolytes
ACIDS, ORGANIC
dissociation constants
intestinal absorption
lipid-solubility
pH values
unionized forms
ACORUS CALAMIJS
acute toxicity
hypnotic potentiating action
hypothermic action
peripheral vascular effects
pharmacological actions
volatile oil
ACTHanterior pituitary release
human subjects
intravenous injection
morphine activation
morphine influence
nalorphine influence8132 pituitary-adrenal system
8132 plasma hydrocortisone levels
vasopressin pretreatment
ADRENAL GLANDS
ACTH administration
8132 ascorbic acid content
8132 human subjects
hydrocortisone releasehypothalamic lesions
8132 morphine
8132 morphine influence
weight
8144 ADRENERGIC AGENTS
8121 atropine blockade
8144 brain transections8144 EEC activation
8121 ADRENERGIC BLOCKADE8144 catechol amine pressor
8121 responses
dibenzyline
8141 hecylamine interactions
ALCOHOL, ETHYL8141 acorus oil8141 chlorpromazine
reserpine
8141 sleeping time
8141 ALCOHOL INTOXICATION,
EXPERIMENTAL
8123 action duration
8141 heart rate
8123 megimide influence
ALKALOSIS
8136 cytoplasmic PBSH 8141
8142
8142
8142
8127
8127
8127
8144
8144
8144
8144
8144
8144
8144
8144
8144
8144
8144
8144
8144
8144
8103
8103
81158103
8113
811381138113
8115
81158115
81108110
8099
8099
81108110
8099
8099
ALK-ANT
SUBJECT INDEX
VOL. 125
S-2
mersalyl-induced diuresis
plasma/CSF distribution
ratios 8123
specific renal cells 8141
weak electrolytes 8123
a-AMINOBENZOIC AC IDplasma/CSF distribution
ratio
p-AMINOHIPPURATEchlorothiazide 8101
renal excretion 8138stop-flow analysis 8101
tetracycline comparison 8138
urine concentrations 8101
AMPHETAMINE
acorus oil pretreatment 8147
pretreatment hyperactivity 8143
reserpine protective action 8147
toxicity 8147
Win 4981 toxicity 8143
d-ANPHETAMINE
atropine antagonism 8145
brain transections 8145
EEC pattern 8145indolylethylpyri dine
antagonism
motor activity
ANALEPTICS
CNS depressants 8146megimide 8146
pentylenetetrazol comparison 8146
ANALGESIA
morphine comparison
oxymorphone
ANALGESICSantagonistic action
chronic narcotic
administration 8112
enzymatic N-dealkylation 8112
morphine antidiuresis 8113phenyl quinone writhing
response
pituitary-adrenal system
ANESTHESIA, BARBITURATE
barbiturate stereoisomers 8102
methohexital 8102
Alpha-ANGELICALACTONE
contraction height 8105inotropic response 8105perfused guinea pig ventricle 8105
potassium loss 8105
8141 ANOXIA
cocaine response
potassium outflux
sciatic nerve
ANTIARRHYTHNIA AGENTSazacycl onol
epinephrine -induced
8123 arrhythmias
epinephrine -induced
hyperkal emi a
ANTICHOLINERGIC AGENTS
ganglionic transmission
gastric secretion
heart rate
intestinal motility
isolated smooth muscle
methacholine -induced
lacrimation
neuromuscular transmission
oxyphencyclimine comparisonspancreatic secretion
pupil diameter
salivary secretion
spasmolytic activity
urinary bladder
8115 vagolytic action
8115 ANTICONVULSANTSfighting behavior
footshock response
indolylethylpyridines
suppressive effects
ANTIDIURE SIS
8114 antidiuretic hormone
8114 hypothalamic lesionsmorphine
8132 pituitary-adrenal system
ANTIEMETIC AGENTSapomorphine-induced emesis
chi orpromazine
indolylethylpyri dines
ANTIHISTAMINE S
8132 carbinoxamine
8113 histamine
histamine-induced spasms
intestinal strips
intra-intestinal pressure
oxypanamine
tripelennamine
8110
tripelennamine metabolites
8124
8124
8124
ANT-BEN
8124
8124
8124
8124
8124
8124
8135
8135
8135
81358135
81278127
8127
8127
8127
8127
8127
810281028102
8102
8102
8104
81048104
8146
81468104
8136
8136
813681368136
8146
81468146
8146
8146
8146
8146
1959SUBJECT INDEX
S-3
ANTIPYRINEbrain
distribution ratio
extradural fluid
phenyl quinone writhing
response
plasma/CSF distribution
ratio
protective action
skeletal muscle
ventricular fluid
vertebrate classes
ARECOLINE
atropine antagonism
spinal cord reflexes
ARTERIES, CORONARY
cardi odynami cs
coronary blood flow
intraarterial injection
MRD-255
papaverine
ASCORBIC ACID
brain
distribution ratios
extradural fluid
plasma/CSF barrier
skeletal muscle
vertebrate classes
ATROPINE
adrenergic drugs
antagonistic action
anticholinergic actions
cholinergic drugs
EEC patterns
gastric secretion
midbrain transections
oxyphencyclimine comparison
postpontine preparation
prepontine preparation
spinal cord reflexes
tricyclamol comparison
ATROPINE NETHYLNITRATE
spinal cord reflexes
AVOIDANCE BEHAVIOR
avoidance training
central electrical activity
conditioned avoidance
response
EEC patternsmorphine
secobarb i tal
AVOIDANCE TRAINING
avoidance behavior
conditioned avoidance
response
EEC patterns
8132 electrophysiological
correlates
8123 tracer conditioned stimulus
8132 AZACYCLONOL
8124 adrenergic blocking action
8124 antiarrhythmia effect
8124 epinephrine-induced
arrhythmi as
8121 epinephrine-induced
8121 hyperglycemia
epinephrine -induced
hyperkalemia
plasma potassium levels
sympathomimetic amines
8128
8128
8128
8128
8128
BARBITURATE STERIOISOIIERSmethohexi talpharmacological actions
potency variation
side effects
therapeutic index
BARBITURATES
cortical responses
8145 EEG
8145 evoked potentials
8144 megimide antagonism
8145 pentylenetetrazol antagonism
8145 subcortical responses
8108 BASES, ORGANIC8145 dissociation constants
8144 intestinal absorption
8145 lipid-solubility
8145 pH values
8121 unionized forms
8108 BENEGRIDE
analeptic effect
8121 blood pressure
convulsant action
8135 morphine-induced circulatory
8135 depressionmorphine-induced respiratory
8135 depression
8135 neurodepressor substances
8134 pentobarbital-induced
8134 circulatory depression
81468146
81038103
8103
8120
8120
8120
8130
8130
8130
8130
8144
8144
8144
8147
8144
81478145
8144
8110
8145
81278145
8129
8145
8144
8129
8107
8147
81228145
8129
81318144
8127
8147
8129
8109
8127
8146
8128
8121
8143
81078109
81448128
8146
8128
8131
8122
8121
8121
8122
8126
8107
8147
8144
8143
8127
8127
chlorothiazide concentrations 8139
drug distribution ratios 8123
8124
intravenous administration 8139
8123
8137
8124
8124
81098129
8109
8129
8109
8109
8109
BEM-BLO
SUBJECT INDEX
VOL. 125
S-4
pentobarbi tal -induced
respiratory depression
pentylenetetrazol compari son
BENZILIC ACID AMIDE
fighting episodes
footshock response
suppressive effect
BENZOQUINONIUM
blocking action
contractile response
direct muscle stimulation
BIOASSAY
drug interactions
neuromuscular blocking agents
rabbit head-drop test
time course
3,6 -BIS(3 -DIETHYLAMINOPROPOXY)
PYRIDAZINE BISMETHIODIDE
(WIN 4981)
action site
acute toxicity
amphetamine pretreatment
chlormethazanone pretreatment
choline antagonism
choline pretreatment
edrophonium antagonism
neuromuscular blocking action
BLADDER
anticholinergic agents
intravesical pressure
oxyphencyclimine inhibition
pelvic nerve stimulation
BLOOD
plasma/CSF barrier
8124
proniazine-S35 concentrations
skeletal muscle
vertebrate classes
BLOOD FLOWblood pressure
catechol amines
femoral artery
8129
hecylamine
histamine
intra-arterial injections
oxypanamine
BLOOD PRESSURE
acorus oil
acetylcholine response
adrenergic blockade
adrenergic drugs
anticholinergic agents
antihistamines
atropine
azacyclonol effect
brain transections
catechol amines
cholinergic drugs
C-O reflex response
cocaine
cocaine sensitization
depressor activity
differential activity
EEG patterns
ephedrine
8143 epinephrine interactions
8143 epinephrine response
8143 epinephrine responses
8143 ganglionic blockade
8143 hecylamine interactions
8143 hypotensive action
8143 8110
8143 isoproterenol responses
megimide antagonism
8144 MRD-255
neurohumoral agents
neuromuscular blocking agents
1-norepinephrine response
oxypanamine
8110
oxyphencyclimine
papaverine
pentobarbital depression
pitressin pretreatment
psychotomimetic agents
reserpine pretreatment
spinal cord reflexes
stabilization
sympathotnimetic amines
tachyphylaxi s
tyramine response
vagal blockade
vagolytic actions
Win 4981
BLOOD SUGAR
azacyclonol effect
epinephrine response
8116
8135
8145
81168145
81048135
81358145
BLO-CEN
8131
8131
8131
8142
8142
8142
81318131
8131
8131
8105
8105
8105
8105
81358104
81248135
8104
8111
8104
8104
8145
8104
8124
8145
8145
811681458112
8104
8104
8104
8104
8104
1959
SUBJECT INDEX
S-5
BLOOD VOLUME, RED1.�TIONhematocri t
8110
oxypanamine
8110
BRAIN
acetazolamide S-35
concentration
acquired electrical activity
adrenergic drugs
anatomic localization
atropine antagoni sm
auditory stimulation
avoidance behavior
avoidance training
cholinergic drugs
chronic narcotic
administration
N-C14-methyl levorphanol
conditioned avoi dance
response (CAR)
cortical responses
drug distribution ratios
EEC patterns
8145
evoked potentials
intracellular distribution
meprobamat e
midbrain reticular formation
midbrain transections
pentobarbi tal
plasma/CSF barrier
postpontine transection
prepontine transection
radioas say
scopolamine antagoni sm
serotonin levels
spontaneous electrical
activity
subcortical responses
tracer conditioned stimulus
(TCS)
vertebrate classes
BRAIN STEM
ascending reticular system
auditory stimulation
evoked potentials
meprobamate
pentobarbital
2 -BROM-LYSERGIC ACID
8109 DIETHYLANIDE
epinephrine
8109 nictitating membrane
potentiating action
BUFO M�RINUS
cocaine
potassium outflux
toad sciatic nerve
BUFOTENINE
denervated nictitating
membrane
epinephrine
nictitating membrane
potentiating action
8112 CARDIAC GLYCOSIDES
8111 contracture
inotropic response
isolated heart ventricle
potassium exchange
CARDIOVASCULAR SYSTEM
aortic pressure
azacyclonol effect
catechol isomers
epinephrine responses
ventricular contractile
CASSAIDINE
antiveratrine activity
single muscle twitch
CASSAINE
antiveratrine activity
single muscle twitch
CATECHOL AMINE S
cocaine interactions
ephedrine interactions
hecylamine interactions
8135 pressor responses
8104 CATECHOL ISOMERS
aortic pressure
8135 inotropic activity
8124 related compounds
CENTRAL NERVOUS SYSTEM
ant iconvul sants
avoidance behavior
behavior studies
depressants
8115 8146
8126
8127
8126
8127force 8126
8106
8106
81068106
8129
8129
8129
8129
8126
8126
8126
81038134
8103
8103
8134
8124
8134
81038103
8115
8115
8115
8103
81468134
81158121
8146
8124
8103
8134
8121
810381038103
8124
8116
8124
8123
8123
8124
812381238123
8123
8123
81248123
8124
drug ionization
extradural fluid
general methodology
pH gradients
pKa values
plasma-CSF barrier
8124
8101
81408140
8139
8139
8140
8140
8140
8139
8140
8101
8139
8139
8101
8139
8139
8139
8139
8101
8101
8139
8101
8139
8101
8101
8115
8115
8137
8137
8115
8143
81438143
8143
8143
8145
8145
8145
8147
8147
8146
8146
8146
8147
8101
8139
8139
81398139
8101
8140
SUBJECT INDEX
VOL. 125
S -6
CEN-CIR
differential depressant
effect
drug distribution ratios
escape behavior
fighting episodes
footshock response
indolylethylpyri dines
interneuronal blockade
linguomandibular reflex
maximal electroshock seizures
megimide stimulation
morphine
motor activity
neurohumoral agents
pentylenetetrazol stimulation
plasma/CSF barrier
rage reaction
secobarbi tal
spinal cord reflexes
spontaneous motor activity
stimulus intensity
suppressive effect
vertebrate classes
CEREBROSPINAL FLUID
acetazolamide S-35 content
brain
drug distribution ratios
8124
plasma-protein binding
skeletal muscle
sulfonamide concentrations
ventricular fluid
vertebrate classes
CHLOR}IETHAZANONEpretreatment hypoactivity
Win 4981 toxicity
CHLOROTHIAZIDE
action site
biliary excretion
body fluid distribution
C14-activity
colorimetry
creatinine concentrations
electrolyte excretion
electrolyte reabsorption
“free” water clearance
glomerular filtration rate
identi fication
intravenous administration
kidney function
maximal water diuresis
mersalyl comparison
nephrectotny
osmolar clearance
PAR concentrations
physiological disposition
plasma concentrations
potassium transport
quantitative determination
renal electrolyte clearances
renal excretion
renal penicillin clearance
renal tubules
sodium transport
solubi li ty
stop-flow analysis
tissue distribution
urine volume
8140
water reabsorption
CHLORPRONAZINE
depressant activity
indolylethylpyri dine
metabolic fate
promazine-S35 comparison
sedation
CHOLINE
analogues
antagonizing action
pretreatment effect
d-tubocurarine neuromuscular
blockade
Win 4981 neuromuscular
8124 blockade
CHOLINERGIC DRUGS
8143 atropine blockade
8143 brain transections
EEC activation response
CIRCULATORY SYSTEM
acorus oil
blood pressure
megimi de antagonism
morphine depression
pentobarbital depression
peripheral vascular effects
8142
8129
8129
8131
8129
8107
8142
8107
8107
liberation
COC -DIP
8112
8112
8112
8112
81208130
81208130
8120
8130
8109
81098130
81318118
8131
8118
81318118
8105
8105
8105
8105
8105
8105
8142
81318129
8142
8107
8107
8107
8107
8135
8135
8135
8135
8135
8135
8120
8120
agents 8120
8126
force 8126
8126
force 8126
8106
8106
81068106
8106
81038103
8103
8144
8144
8119
1959
SUBJECT INDEX
S-7
COCAINE
anoxia influence
catechol amine interactions
ephedrine interactions
epinephrine contractile
response
hecylamine interactions
intravenous injection
iodoacetate influence
nerve stimulation
nictitating membrane
8131
1-norepinephrine response
plasma 1-norepinephrine
concentration
potassium outflux kinetics
potentiating action
pressor responses
sciatic nerve
splenic sympathin
splenic volume
supersensi tivi ty
tyramine response
CONDITIONED REFLEXES
avoidance behavior
avoidance training
central electrical activity
conditioned avoidance
response (CAR)
EEC patterns
reserpine blockade
tracer conditioned stimulus
(TCS)
CONTRACTION
direct muscle stimulation
gastrocnemius muscle
neuromuscular blocking
CONVULSANTS
megimi de
morphine influence
CORONARY BLOOD FLOW
MRD -2 55pitressin pretreatment
COUMINGINE
antiveratrine activity
single muscle twitch
CYCLOPROPANEdepressant action
3-OH PTEA response
repetitive presynaptic
activity
DEALKYLATION
analgesic response
chronic narcotic
administration
liver enzyme activity
testosterone
DECAMETRONIUM
contractile response
decamethonium pretreatment
direct muscle stimulation
head-drop assay
indirect muscle stimulation
8107 neostigmine antagonism
neuromuscular blockade
8107 oxypanamine
d-tubocurarine interaction
DIBENAMINE
epinephrine
epinephrine -arrhythmia
nictitating membrane
potassium infusion
potentiating action
pretreatment
DIHYDRO-OUABAIN
contracture
heart rate
heart rhythm
inotropic response
perfused guinea pig ventricle
potassium loss
DIHYDROXYBENZENES
aortic pressure
8135 ventricular contractile
dl-DIHYDROXYPHENYLALANINE
aortic pressure
ventricular contractile
DIMETHYLAMINOETHANOL
antiveratrine activity
8146 erythrophleum alkaloids
8146 DIMETHYLANINOETHANOL PIMELATE
antiveratrine activity8128 erythrophleum alkaloids
8128 single muscle twitch
DIPHENHYDRAMINE
8106 fighting episodes
8106 footshock response
suppressive effect
8119 DIPHENMETHANIL METHYLSULFATE
8119 anticholinergic actions
oxyphencyclim.tne comparison
8127
8103
8103
8103
8136
8136
8101
8101
8101
8141
8140
8140
8140
8141
8140
8141
8141
8104
8145
8104
8145
8145
8104
8135
8123
8123
8101
8139
8140
8123
8139
8139
8140
8101
8101
8115
8115
8115
8112
8112
8129
81298129
8129
8129
8129
8122
8122
8127
8127
8127
8129
8129
8129
8129
8127
81278129
8118
8118
8118
DIP-EPI
SUBJECT INDEX
VOL. 125
5-8
DIPHENYLHYDANTOIN
anticonvulsant activity
cardiac arrhythmia
epinephrine -induced
hyperkalemia
fighting episodes
footshock response
suppressive effect
DISSOCIATION CONSTANTS
intestinal absorption
organic compounds
DIURETICSchlorothiazi de
kidney tubular function
stop-flow analysis
DIURETICS, MERCURIAL
acid-base balance
chlorothiazide comparison
kidney function
maximal water diuresis
mercuric chloride
mer sal yl
8141
protein-bound sul fhydryl
changes
specific renal cells
EDROPHONIUM
antagonizing action
d-tubocurarine neuromuscular
blockade
Win 4981 neuromuscular
blockade
ELECTROCARDIOGRAM
cardiac arrhythmia
1-epinephrine
hyperkalemia
ELECTROENCEPHALOGRAM
adrenergic drugs
atropine
auditory stimulation
avoidance training
basic patterns
cholinergic drugs
conditioned avoidance
response
cortical responses
electrophysiological
correlates
evoked potentials
meprobamate
8103 midbrain transections
8127 pentobarbital
postpontine preparation
prepontine preparation
subcortical responses
tracer conditioned stimulus
(TCS)ELECTROLYTES
acidosis
alkalosi s
chlorothiazi de
8140
chlorothiazide influence
mer sal yl
plasma/CSF distribution
ratios
probenecid influence
renal clearance
renal excretion
renal tubular transport
stop-flow analysis
ELECTROSHOCKdiphenylhydantoin
indolylethylpyridine
antagonism
MES
ENZYMES
chronic narcotic
8143 administration
N-dealkylation
8143 EPHEDRINE
arterial pressure
8143 catechol amine interaction
cocaine interactions
dibenzyline blockade
femoral arterial blood flow
hecylamine interaction
pressor response
8145 reserpine pretreatment
8145 EPINEPHRINE
8104 azacyclonol effect
8135 blood glucose response
8145 cardiovascular responses
8145 cocaine pretreatment
dibenzyline blockade
8135 ephedrine potentiation
8104 hecylamine interaction
hyperkalemia
8135 metabolic responses
8104 pressor response
8118
8145
8145
8118
8145
8131
8131
8121
8118
8122
8131
8122
8121
8106
8106
8106
8106
8106
8106
8106
EPI-HEA
8144
8110
8108
8108
8108
8144
8144
8108
8110
8144
8144
8144
8144
8138
8138
8138
8138
8138
8138
8140
8140
8131
8131
8131
8128
8128
8128
8128
8128
8128
8128
8127
8127
8127
8118
8118
8118
8127
8117
8117
8117
8117
8117
8117
8117
8117
8120
8120
8120
8129
8129
8129
8144
8108
8144
8108
8108
1959SUBJECT INDEX
S -9
1-EPINEPHRINE
arterial plasma
atropine antagonism
brain transections
cardiac arrhythmia
EEC pattern
hypersensitivity
nictitating membrane
phenoxybenzamine pretreatment
potassium concentration
pressor response
psychotomimetic potentiation
reserpine pretreatment
spinal cord reflexes
ERYTHROPHLEINE
antiveratrine activity
single muscle twitch
ERYTHROPHLEUN ALKALOIDS
antiveratrine activity
frog sartorius
maximal tetanic tension
reversibility
single muscle twitch
ESCAPE BEHAVIOR
morphine
secobarbi tal
FLUORIDE
glucose concentration
metabolic aspects
oxygen consumption
positive inotropic effect
pyruvate concentration
stimulation frequencysubstrate variation
ventricle muscle strips
GALLAMINE
contractile response
direct muscle stimulation
indirect muscle stimulation
GANGLIONIC BLOCKADE
hecylamine pressor response
hexame thoni um
mecamyl amine
GASTRIC SECRETION
anticholinergic agents
atropine
chronic gastric fistulas
denervated gastric pouches
double-meal response
fluid volume
histamine
histamine-stimulated
8144
innervated gastric pouches
insulin-stimulated
intraduodenal administration
liver-broth-induced
meal -stimulated
oxypanamine
oxyphencyclimine comparisons
pH values
pylorus-ligated rats
rumenal ulceration
GASTROINTESTINAL SYSTEM
administration sites
colon
duodenum
ileum
stomach
tetracycline absorption
GLOMERULAR FILTRATION RATE
8134 chlorothiazide
8134 mersalyl
HARMINE
epinephrine contractile
response
nictitating membrane
potentiating action
HEART
cardiac output
cardiac work
coronary blood flow
NRD -255
myocardial oxygen
utilization
papaverinerate changes
HEART ARRHYTHMIA
antiarrhythmia agents
azacyclonol effects
epinephrine -induced
1-epinephrine
hyperkalemia
liver exclusion
plasma potassium levels
8109
8105
8105
8105
8105
8105
8105
8109
8105
8105
8105
8105
8109
8105
8105
8105
8146
8144
8146
8128
8144
8128
8128
8126
8126
8126
8117
8117
8117
8117
8117
8117
8117
8120
8120
8120
8129
8129
8129
8129
8129
8129
8129
8129
8109
8110
8110
8108
8108
8110
8109
8110
8110
8109
8109
8121
8110
8110
8110
8133
8133
8133
8133
8133
8123
8123
8123
8136
8136
8119
8119
8119
8119
8119
8119
8119
HEA-HYD
SUBJECT INDEX
VOL. 125
S-lO
HEART ISOLATED
contractile force
contraction height
contrac ture
ECG
8109
electrical activity
guinea pig ventricle
half-calcium perfusion
heart-lung preparation
hypodynamic control level
inotropic response
membrane potential
nonsteroid lactones
oxypanami ne
potassium exchange
rhythm changes
steroid lactones
HEART RATE
alcohol intoxication
anticholinergic agentsmegimide influence
MRD-2 55
oxyphencyclimine compari son
papaverine
pitressin pretreatment
HEART VENTRICLE
aortic pressure
catechol isomers
contractile force
fluoride
glucose concentration
inotropic response
oxygen consumption
pyruvate concentration
stimulation frequency
substrate variation
REXAMETHONIUM
contractile response
direct muscle stimulation
indirect muscle stimulation
HEXOBARBITAL
acorus oil
anesthetic action
chlorpromazi ne
oxypanamine potentiation
reserpine
sleeping time
HEXOBARBITAL ANESTHESIA
duration
indolyl ethylpyri dines
HEXYL-Beta-CYCLOHEXYLETHYLA.MINE
arterial pressure
catechol amine interactions
cocaine interactions
dibenzyline blockade
ephedrine interaction
femoral arterial blood flow
ganglionic blocking agents
peripheral vascular
resi stance
HISTAMINE
arterial blood flow
blood level
compound 48/80
cyclamol inhibition
gastric secretion
8110
intra-intestinal pressure
intratracheal pressure
8110
lethal toxicity
liberation
oxypanamine
8110
pulmonary arterial pressure
8110
spinal cord reflexes
systemic arterial pressure
tripelennamine blockadevasodepressor response
HYDROCORTISONE
human subjects
morphine response
nalorphine response
plasma levels
vasopressin response
HYDROGEN ION CONCENTRATION
blood
cerebrospinal fluid
drug distribution ratios
intestinal absorption
organic compounds
8147 3 -HYDROXY PHENYLTRIETHYL-
8109 AMMONIUM ION
8147 cyclopropane dissociation
8109 intraarterial injection
8147 motor nerve terminal
8147 muscle repetitive activity
nerve repetitive activity
8115 neuromuscular transmission
8115 pentobarbital dissociation
HYD-ISO
8119
8119
8126
8126
8126
8127
8127
8127
8144
8147
8144
8110
8144
8144
8110
8110
8110
8110
8144
8144
8147
8136
81368136
8136
8136
8136
8136
8138
8136
8136
8138
8147
8147
8147
8147
8147
8147
8142
8142
8142
8144
8144
8127
8127
8118
8118
8118
8118
8113
8113
8113
8113
8113
8113
8113
8115
8115
8115
8115
8115
8115
8115
8115
8115
8115
8115
1959
SUBJECT INDEX
S-Il
postactivation repetition
procaine dissociation
repetitive antidromic
discharge
twitch tension potentiation
HYDROXYAMPHETANINE
hecylamine
pressor responses
5 -HYDROXYTRYPTAMINE
aortic pressure
tachyphyl axis
ventricular contractile force
HYPERGLYCEMIA
azacyclonol effect
epinephrine -induced
HYPERKALEMIA
azacyclonol effect
blocking agents
cardiac arrhythmia
epinephrine -induced
HYPNOTICS
acorus oil
sleeping time
HYPOTHALAMUS
adrenal ascorbic acid
depletion
adrenal weightsdestruction sites
morphine antidiuresis
pituitary-adrenal activation
testicular weights
water load excretion
INDOLYLETHYLPYRIDINES
acute toxicities
d-amphetamine
anticonvulsant effects
central nervous system
chemical specificity
chlorpromazine comparison
depressant effects
hexobarbital anesthesia
meprobamate comparison
miscellaneous actions
motor activity
INOTROPISM
catechol isomers
INSULINcyclamol inhibition
gastric secretion
8119 INTESTINAL MOTILITY
8119 acetylcholine-induced
contractions
acorus oil
anticholinergic agents
atropine
8129 charcoal meal test
8129 gastrointestinal propulsionhistamine
intra-luminal pressure
isolated ileum
oxypanamine
oxyphencyclimine comparison
8127 Thiry-Vella fistulas
8127 INTESTINE
acorus oil
dissociation constants
drug absorption
lipid-solubility
8127 lumen drug ccncentrations
organic compounds
8147 pH gradients
8147 plasma drug concentrations
tetracycline absorption
transport mechanism
unionized forms
vascularly intact loops
volume changes
INTESTINE, ISOLATED
acetylcholine response
acorus oil inhibiting action
barium chloride response
guinea pig ileum
histamine response
IODOACETATE
cocaine response
potassium outflux
sciatic nerve
ISOPROPAMIDE IODIDE
anticholinergic actions
oxyphenycyclimine comparison
ISOPROTERENOL
azacyclonol effect
cardiovascular responses
dl-ISOPROTERENOL
arterial plasma
cardiac arrhythmia
8126 potassium concentration
potassium infusion
8108 1-ISOPROTERENOL
8108 arterial plasma 8118
8118
8118
8118
8129
8129
8129
force 8126
8111
8139
8111
8140
8141
8140
8138
8141
8139
8141
8138
8139
8138
81018101
8101
8101
8101
8101
8139
8139
8139
8144
8144
8144
8105
8105
8105
81058105
8105
8103
8103
8103
8103
8104
8104
8115
8104
8104
8103
8103
8115
ISO-MEP
SUBJECT INDEXVOL. 125
S -12
cardiac arrhythmia
potassium concentration
potassium infusion
KIDNEY
acid-base balance
chlorothiazide
8140
N-Cl4-methyl 1 evorphanol
glomerular filtration rate
8140
intracellular distribution
maximal water diuresis
mercurial-induced diuresis
me r sal yl
PAR excretion
protein-bound sulfhydryl
changes
renal clearance studies
specific renal cells
tetracycline excretion
tubular secretion
unilateral infusion
KIDNEY TUBULAR FUNCTION
chlorothiazi de
electrolyte reabsorption
potassium transport
sodium transport
stop-flow analysis
water reabsorption
KIDNEY TUBULAR TRANSPORT
chlorothiazide secretion
penicillin secretion
probenecid inhibition
LACRIMATION
anticholinergic agents
methacholine -induced
oxyphencyclimine
LACTONES
concentration
contraction height
contracture
inotropic response
isolated heart ventricle
potassium exchange
LEVARTERENOL
aortic pressure
cocaine interaction
ephedrine interaction
hecylamine interactions
pressor response
ventricular contractile
LEVORPHANOL, N-&-4-METHYL
brain
8141 intracellular distribution
8139 kidney
liver
LIPID -SOLUBILITY
intestinal absorption
organic compounds
LIVER
chronic narcotic
administration
circulatory exclusion
N-C14-methyl levorphanol
enzymatic N-dealkylation
epinephrine -arrhythmia
epinephrine -induced
hyperkalemia
intracellular distribution
potassium infusion
LUNG CIRCULATION
oxypanamine
pulmonary arterial pressure
LYSERGIC ACID DIETHYLAMIDE
analoguesdenervated nictitating
membrane
epinephrine contractile
response
nictitating membrane
potentiating threshold doses
MEPHENESIN
fighting episodes
footshock response
suppressive effect
MEPROBAMATE
anticonvulsant activity
auditory stimulation
cortical responses
depressant activity
EEGevoked potentials
fighting episodes
foot shock response
8126 indolylethylpyridine
8129
8111
8111
8111
8111
8136
8136
8112
8118
8111
8112
8118
8118
8111
8118
8109
8109
8131
8131
8131
8131
8131
MEP-MOR
8140
8140
8140
8140
8140
8140
8140
8140
8131
8131
8131
8128
8128
8129
8129
8129
8129
8146
8146
8146
8102
8102
8102
8145
8145
8145
8145
8145
8145
8133
8113
8113
8113
8113
8114
8112
8113
8113
8134
8112
8146
8134
8112
8134
8133
8113
8146
8146
8114
8113
8144
8144
8144
8145
8145
8145
8144
8144
8129
81298129
8129
8128
8128
8128
8128
8128
8128
1959
SUBJECT INDEX
S-l3
subcortical responses
suppressive effect
tranquilizing action
MERSALYL
acid-base balance
electrolyte excretion
protein-bound sulfhydryl
changes
specific renal cells
water excretion
MERSALYL SODIUM-THEOPHYLLINE
chlorothiazide comparison
electrolyte excretion
“free” water clearance
glomerular filtration rate
kidney function
maximal water diuresis
osmolar clearance
urine volume
MESCALINE
epinephrine contractile
response
nictitating membrane
potentiating action
METABOLISM
azacyclonol effect
epinephrine responses
NETHACHOLINE
anticholinergic agents
lacrimation response
oxyphencyc 1 imine
METHAMPHETAI4INE
atropine antagonism
brain transections
EEC pattern
METHSCOPOLAMINE BROMIDE
anticholinergic actions
oxyphencyc limine compari son
Alpha-METHYLARTERENOLcocaine interactions
ephedrine interactionshecylamine interactions
pressor response
N-METRYL-N-CINNAMYL-2-PHENYL-
PROPYLAMINE (MRD-255)
blood pressure
cardiodynamic s
coronary blood flow
heart rate
intracoronary administration
intravenous administration
8104
8103
8104
myocardial oxygen consumption
pitressin pretreatment
Alpha -METHYLEPINEPHRINEcocaine interaction
8141 ephedrine interaction
8141 hecylamine interactions
pressor responses
8141 Beta-METHYL-Beta-ETHYL-
8141 GLUTARAMIDE
8141 analeptic effect
antagonistic action
neurodepressor substances
1 -METHYL-5-(l -METHYL-2-
PENTYNYL) -5 -ALLYL-BARBITURIC
ACID
alpha dl-isomer
(methohexi tal)
pharmacological actions
stereoi somers
MIDBRAIN
adrenergic drugs
atropine
cholinergic drugs
EEC patternsscopolamine
8127 transverse sections
8127 MORPHINE
ACTH injection
ACTH release
8133
ADH (vasopressin) release
adrenal ascorbic acid
depletion
adrenal weights
analgesic equivalence
analgesic response
anterior pituitary
antidiuretic response
avoidance behavior
chronic administration
circulatory depression
differential depressant
effect
enzymatic N-demethylation
escape behavior
human subjects
hypothalamic lesions
megimide antagonism
megimide convulsions
oxymorphone comparison
pituitary-adrenal activation
plasma hydrocortisone levels 8133 human subjects
8146 pituitary-adrenal system
8114 plasma hydrocortisone levels
8113 tolerance
8112 NEOSTICMINE
8133 antagonistic action
8113 atropine antagonism
blocking action
8112 contractile response
8112 direct muscle stimulation
8112 methyl atropine antagonism
neuromuscular blocking agents
spinal cord reflexes
NEPHRECTONY
biliary excretion
drug distribution
HC1 infusion
8120
8120
8106
8106
8120
8106
agents 8120
8106
8106
plasma clilorothiazide
concentrations
plasma/CSF concentration
ratios
NERVE
cocaine
K42 content
membrane permeability
metabolic inhibition
potassium outflux kinetics
toad sciatic nerve
NEUROHUMORAL AGENTSprimary central effects
spinal cord reflexes
synaptic transmission
vascular changes
NEUROMUSCULAR BLOCKADE
neostigmine response
oxypanami ne
NEUROMUSCULAR BLOCKING AGENTS
action site
cat sciatic-gastrocneinius
choline reversal
denervated muscle
direct stimulation
edrophonium reversal
head-drop assay
indirect stimulation
interactions
neostigmine antagonism
skeletal muscle contraction
time course
d-tubocurarine comparison
Win 4981
MOR-NEU
SUBJECT INDEX
VOL. 125
S-14
8133
respiratory depression 8133
side action liability 8133
testicular weights 8112
testosterone
vasopressin response 8130
water load excretion 8121
MORPHINE-NALORPHINE MIXTURES 8120
analgesic response 8120
chronic administration 8120
enzymatic N-dealkylation 8121
MUSCLE, SKELETAL 8130
contractile response 8121
direct stimulation
erythrophleum alkaloids 8139
frog sartorius 8123
indirect stimulation 8123
maximal tetanic tension
neuromuscular blocking 8139
single twitch
veratrine response 8123
MUSCLE, SMOOTH
acetylcholine 8110 8142
anticholinergic agents 8144 8142
carbinoxamine 8110 8142
guinea pig ileum 8144 8142
histamine 8110 8142
intestinal stimulant action 8110 8142
isolated ileum 8110
oxypanamine 8110 8121
oxyphencyclimine comparisons 8144 8121
rabbit ileum 8144 8121
rat uterus 8144 8121
spasmolytic activity 8144
tripelennamine 8110 8109
8109
NALORPHINE 8143
ACTH release 8133 8143
analgesic response 8112 8143
chronic administration 8112 8120
enzymatic N-dealkyration 8112 8120
human subjects 8133 8143
plasma hydrocortisorte levels 8133 8130
NARCOTICS 8120
analgesic response 8112 8130
brain serotonin levels 8112 8130
chronic administration 8112 8120
cross-tolerance 8112 8130
enzymatic N-dealkylation 8112 8143
8143
8144
8107
8109
NIC-OXY
8117
8117
8128
8128
8117
8114
8114
8114
8114
8110
8109
8110
8110
8110
8110
8109
8110
8109
8110
8109
8109
8110
8109
8110
8110
8110
8110
8109
8110
8109
8109
8109
8109
8109
8109
8109
8110
8109
8110
8109
8105
8105
8105
8105
8105
8105
8105
1959
SUBJECT INDEX
S-15
NICTITATING MEMBRANE
acetylcholine
cocaine sensitization
contraction response
8131 8144
denervati on
epinephrine
8131
lysergic acid derivatives
nerve stimulation
8109
1-norepinephrine response
oxypanami ne
oxyphencyclimine
psychotomimetic potentiation
sympathetic nerve stimulation
tetramethylammonium
tyramine response
dl-NOREPINEPHRINE
pressor response
reserpine pretreatment
1-NOREPINEPHRINE
cocaine -induced
supersensi tivity
delayed inactivation
phenoxybenzamine pretreatment
plasma concentration
pressor response
spinal cord reflexes
NORMORPHINE
analgesic response
chronic administration
liver enzyme activity
ORMOSIA PANAMENSIS
active alkaloids
8110
oxypanami ne
8110
pharmacological actions
8110
OUABAINcontraction height
contracture
heart rate
heart rhythm
inotropic response
perfused guinea pig ventricle
potassium loss
OXYGEN CONSUMPTION, CARDIACcontraction force
fluoride
MRD -255
papaveri ne
8131 ventricle muscle strips
8109 OXYMORPHONE
analgesic equivalence
8131 morphine comparison
8107 relative potencies
side action liability
8107 OXYPANAMINE
8109 antihistamines
81.44 arterial blood flow
8131 blood clotting time
8144 blood histamine level
8109 bronchoconstriction
8107 carbinoxamine
chemical specificity
8122 compound 48/80
8122 ganglionic blocking action
gastric secretion
gastrointestinal absorption
8107 hemoconcentration
8107 8110
8121 hemophilus pertussis vaccine
8107 hexobarbital potentiating
8107 action
8121 histaminehistamine-like actions
8112 hypotensive action
8112 intra-intestinal pressure
8112 intratracheal pressure
8110
isolated ileum
lethal toxicity
8109 8110
neostigmine antagonism
8109 neuromuscular blockade
nictitating membrane
8109 pharmacological actions
8110
pulmonary arterial pressure
8110
species variation
systemic arterial pressure
tachyphylaxi s
8110
tripelennamine blockade
vasodepressor activity
8110
comparative effects
gastric secretion
activity
reserpine
8144
8144
8144
8144
8144
8144
8144
8144
8144
8144
CNS depressants
convulsant action
8119
8146
8119
8147
8146
8147
8104
8115
8115
8147
8146
8146
8147
8115
8147
8146
8147
8147
8147
8136
8136
8123
8123
8136
8123
8136
8123
8103
8103
8103
8103
8103
8103
8103
8129
8129
8129
8129
8129
8121
8121
8128
8128
8128
8128
8128
8144
8144
8105
8105
8105
8105
8139
8139
8139
81478146
8104
8146
8147
8146
8104
8119
8104
8104
8146
8146
OXY-PHE
SUBJECT INDEX
VOL. 125
S-l6
OXYPHENCYCLIMINE
anticholinergic agents
blood pressure
heart rate
intestinal motility
mydriasis
nictitating membrane
pancreatic secretion
pharmacological actions
salivary secretion
spasmolytic activity
PAIN, CHRONIC
morphine comparison
oxymorphone
PANCREATIC SECRETION
oxyphencycl imine
PAPAVERINE
blood pressure
cardiodynamics
heart rate
intracoronary administration
myocardial oxygen consumption
oxyphencyclimine comparison
spasmolytic activity
PATULIN
contraction height
contracture
perfused guinea-pig ventricle
potassium loss
PENICILLIN
chlorothiazide
probenecid influence
renal clearance
PENTOBARBITAL
acorus oil
action duration
auditory stimulation
blood pressure
chlorpromazine
circulatory depression
cortical responses
depressant action
EEC
evoked potentials
megimide antagonism
mortality rate
3-OH PTEA response
8144 pentylenetetrazol antagonism
8144 repetitive presynaptic
respiratory depression
sleeping time
subcortical responses
PENTOBARBITAL ANESTHESIA
duration
indolylethylpyridines
PENTYLENETETRAZOL
acorus oil influence
analeptic action
8114 indolylethylpyridine
8114 antagonism
lethal effect
8144 megimide comparison
reserpine pretreatment
PERFUSION, RATE
acorus oil concentration
frog hind legs
pH GRADIENTS
absorption site
drug absorption
drug distribution ratios
drug ionization
intestinal lumen
pKa values
plasma
plasma/CSF barrier
PHENOBARBITAL
anticonvulsant activity
fighting episodes
footshock response
suppressive effect
PHENOTHIAZINES
fighting episodes
footshock response
suppressive effect
PHENOXYBENZAMINE
adrenergic blocking action
arterial pressure
ephedrine
epinephrine
hecylamine
serotonin
spinal cord reflexes
8132
8132
8132
8132
8121
8145
8145
8121
8144
8144
8144
8127
8127
8128
8128
8128
8128
8128
8113
8133
8113
8133
8113
8133
8133
8116
8127
8123
8127
8139
8133
8136
8123
8124
8127
8133
8133
PHE -PRO
8136
8136
8139
8107
8136
8133
8133
8139
8107
8123
8123
8127
8123
8124
8133
8124
8142
8118
8118
8142
8118
8118
8118
8142
8118
8118
8118
8142
8142
8118
8105
8105
8105
8105
8105
8105
8101
8101
8101
8139
8139
8139
1959
SUBJECT INDEX
S-l7
PHENYLBUTAZONE
phenylquinone writhing
response
protective action
PHENYLQUINONE
analgesic antagonists
intraperitoneal injection
mouse writhing test
nonanal ge sic antagoni at a
PHYSOSTIGMINE
atropine antagonism
8145
brain transections
EEG patterns
spinal cord reflexes
PILOCARPINE
anticholinergic agents
oxyphencyc limine
salivary secretion
Alpha-4-PIPERIDYL BENZHYDROLantiarrhythmia action
sympathomimetic amines
PITRESSIN
blood pressure
cardiodynamic s
coronary blood flow
heart rate
intravenous MRD-255
PITUITARY-ADRENAL SYSTEM
antidiuresi s
human subjects
hypothalamic lesions
morphine
morphine activation
nalorphine
plasma hydrocortisone levels
PLASMA
acetazolamide S-35 content
azacyclonol effect
blood-CSF barrier
8124
cardiac rhythm
chlorothiazide concentrations
diurnal variations
drug concentration ratios
drug concentrations
drug distribution ratios
epinephrine response
human subjects
hydrocorti sone concentration
intestinal absorption
intestinal lumen
8132 intravenous administration
8132 intravenous cocaine
lipid-solubility
morphine effect
nalorphine effect
nephrec tomy
1-norepinephrine levels
pH gradients
8136
pKa values
8136
potassium concentrations
protein binding
8124
skeletal muscle
vasopressin response
vertebrate classes
POTASSIUM
anoxia influence
arterial plasma levels
cardiac arrhythmia
cocaine depression
dibenamine pretreatment
i-epinephrine
epinephrine -arrhythmia
iodoacetate influence
dl-i soproterenol
1-i soproterenol
liver exclusion
nerve outflux kinetics
sciatic nerve content
ventricular fibrillation
POTASSIUM EXCHANGE
contraction height
contracture
inotropic response
isolated heart ventricle
nonsteroid lactones
steroid lactones
POTASSIUM TRANSPORT
chlorothiazi de
renal tubules
stop-flow analysis
PROBENECID
renal chlorothiazide
clearancerenal electrolyte clearances
renal penicillin clearance
8137
8137
8137
8137
8137
8137
8137
8137
8137
8137
8131
8131
8131
8131
8105
8105
8105
8105
8119
8119
8119
8127
8127
8115
8115
8115
8121
8121
8121
8121
8121
8121
8147
8147
8135
8135
8135
8135
8135
8122
8135
8103
8103
8122
8147
8103
PRO-RES
SUBJECT INDEX
VOL. 125
S-18
PROCAINE
depressant action
3-OH PTEA responserepetitive presynaptic
activity
PROCAINE AMIDE
cardiac arrhythmia
epinephrine -induced
hyperkalemia
PROCHLORPERAZINE
fighting episodes
footshock response
suppressive effect
PROMAZINE -�35
blood levels
chlorpromazine comparison
chromatograms
demethylation
fecal excretion
metabolic fate
metaboli tes
sul foxidation
tissue distribution
urinary excretion
PROPADRINEpressor response
reserpine pretreatment
PROPANTHELINE BROMIDE
anticholinergic actions
oxyphencyclimine compari son
Alpha-dl -PROPOXYPHENE
C1�4-dis tribut ion
C 14labeledfecal C1-4 excretion
human subjects
metabolic fate
metaboli tes
N-demethylati on
pulmonary C1-4O2 excretion
tissue slice C�-4O2 liberation
urinary C14 excretion
PROTEIN, PLASMA
binding
8124
drug distribution ratios
8124
plasma/CSF barrier
8124
PROTEIN, SERUM
tetracycline binding
PSYCHOTOMIMETIC AGENTS
8119 denervated nictitating
8119 membrane
epinephrine interactions
8119 nictitating membrane
potentiating threshold doses
8127 PULVINIC ACID DILACTONEcontraction height
8127 inotropic response
perfused guinea pig ventricle
potassium loss8103
8103
8103
QUATERNARY AMMONIUM IONS
motor nerve terminals
3-OH PTEA
repetitive presynaptic
activity
QUINIDINEcardiac arrhythmia
epinephrine -induced
hyperkalemia
REFLEXES
indolylethylpyridines
8122 interneuronal blockade
8122 mephenesin
REFLEXES, SPINAL CORD
8144 blood pressure elevation
8144 blood pressure stabilization
facilitation
8100 neurohumoral agents
8100 phasic inhibition
8100 vascular effects
8100 RESER.PINE
8100 acorus oil potentiation
8100 amphetamine toxicity
8100 avoidance behavior
8100 avoidance training
8100 CAR blockade
8100 central electrical responses
conditioned avoidance
8123 response (CAR)
differential activity
8123 EEC patterns
fighting episodes
8123 footshock response
pretreatment effect
protective action
8138 suppressive effect
sympathomimetic amines
tracer conditioned stimulus
8122
8135
RES -SPL
neuromuscular blocking agents
oxymo rphone
8145
8131
8115
8146
8114
8146
8143
8114
8109
8144
8146
8131
8143
8144
8144
8145
8145
8145
8145
8145
8134
8134
8115
8115
8115
8112
8121
8112
8131
8131
8131
8121
8131
8121
8138
8138
8101
8101
8101
8144
8144
8144
8144
8144
8144
8121
8121
8121
8107
8107
8107
8125
8125
8125
8125
8125
8125
1959
SUBJECT INDEX
S-l9
RESORCINOL
blood pressure
ventricular contractile
RESPIRATION
acorus oil
adrenergic drugs
anticholinergic agents
atropine
brain transections
bronchoconstriction
choline reversal
cholinergic drugs
depressant effects
8115
EEC patterns
epinephrine interactions
indolylethylpyridines
megimide antagonism
morphine compari son
morphine depression
oxypanami ne
oxyphencyclimine
pentobarbital depression
psychotomimetic agents
Win 4981 paralyzing action
SALICYLAMIDE
chromato grams
glucuronide formation
human subjects
phenylquinone writhing
response
protective action
8132
sulfate conjugation
urinary calculism
urinary metabolites
SALICYLATE, SODIUMphenylquinone writhing
response
protective action
SALICYLATE, SODIUM ACETYL
phenylquinone writhing
response
protective action
SALIVARY SECRETION
anticholinergic agents
oxyphencyclimine comparison
8126 SCOPOLAMINE
force 8126 adrenergic drugs
antagonistic action
8147 brain transections
8145 cholinergic drugs
8144 EEC patterns
8145 SECOBARBITAL
8145 avoidance behavior
8109 escape behavior
8143 SEDATION
8145 chlorpromazine
8114 indolylethylpyridines
meprobamate
SEROTONIN
brain concentration
chloralose anesthesia
chronic narcotic
administration
denervated nictitating
membrane
epinephrine contractile
response
nictitating membrane
phenoxybenzamine pretreatment
potentiating action
spinal cord reflexes
SERUM
gastrointestinal absorption
tetracycline concentrations
SODIUM TRANSPORTchlorothiazide
renal tubules
stop-flow analysis
SPASMOLYTIC AGENTS8132 acetylcholine response
8125 anticholinergic compounds
barium chloride response
histamine response
oxyphencyclimine comparisons
serotonin response
SPINAL CORD
neurohumoral agents
8132 reflex activity
8132 vascular effects
SPLEEN
intravenous cocaine
8132 i-norepinephrine response
8132 splenic nerve stimulation
8120
8120
8130
8120
8109
8109
8130
8130
8130
8130
8123
8123
8123
8123
ratio 8123
morphine N-dealkylation
ratio 8123 TETRACYCLINE
gastrointestinal absorption
ratio 8123 intravenous administration
8126
8126
8107
8107
8127
8127
8122
8122
8122
8147
8113
8113
8113
8113
8112
8112
8112
8112
8138
8138
8138
8138
8138
8138
8104
8104
8104
8104
8104
8104
8104
8144
8144
8109
81-09
8144
8109
8144
8109
ratio 8123
ratio 8123
8141
8141
8141
8141
8141
8141
8141
8124
8124
8123
SPL-TRA
SUBJECT INDEX
VOL. 125
S-2O
sympathin liberation
volume changes
STRYCHNINE
indolylethylpyridine
antagonism
SUBSTANCE P
spinal cord reflexes
SUCCINYLCHOLINE
contractile response
direct muscle stimulation
head-drop assay
indirect muscle stimulation
neuromuscular blockade
oxypanami ne
succinylcholine pretreatment
tachyphylaxi s
time course
d-tubocurarine interaction
SULFADIAZINE
acid infusion
alkali infusion
nephrec tomy
pH gradients
plasma/CSF distribution
8124
SULFAMETHOXYPYRIDAZINEplasma/CSF distribution
SULFANILAMIDEplasma/CSF distribution
8124
SULFANILIC ACID
plasma/CSF distribution
8124
SULFATHIAZOLEplasma/CSF distribution
SULFHYDRYL, PROTEIN-BOUND
acid-base balance
cytophotometric studies
DDD incubation time
mercuric chloride-induced
changes
mersalyl-induced changes
rat kidney cells
specific renal cells
SULFONAMIDES
brain
extradural fluid
plasma/CSF distribution ratio
8124
skeletal muscle
ventricular fluid
8107 SYMPATHETIC NERVOUS SYSTEM
8107 catechol isomers
stimulant effects
SYNPATHIN
8115 intravenous cocaine
splenic liberation
8121 SYMPATHOMINETIC AMINES
azacyclonol effect
cardiovascular responses
differential activity
pressor responses
reserpine pretreatment
TEMPERATURE, RECTAL
acorus oil
TESTEShypothalamic lesions
morphine
pituitary-adrenal system
weight
TESTOSTERONE
analgesic response
chronic administration
liver enzyme activity
probenecid influence
renal clearance
renal excretion
serum protein binding
TRANQUILIZING AGENTS
auditory stimulation
cortical responses
EEC
electrophysiological effects
meprobamat e
pentobarbi tal
subcortical responses
TRANSMISSION, GANGLIONIC
anticholinergic agents
hexame thoni um
C-O pressor response
epinephrine pressor response
nictitating membrane response
oxypanami ne
oxyphencyclimine
8124 tetramethylammonium pressor
8124 response
TRA-VAS
8144
8119
8120
8120
8119
8120
8120
8120
8119
8109
8144
8143
8143
8119
8119
8143
8119
8143
8121
8121
8121
8108
8108
8108
8108
8108
8103
8103
8103
8143
8143
8143
8120
8130
8130
8120
8143
8130
8120
8109
8109
8143
8109
8130
8130
8130
8143
8122
8122
8146
8146
8125
8125
8125
8144
8144
8144
8109
8109
8128
8128
8128
8128
8128
8128
8133
81338133
8126
force 8126
8099
8099
8099
8099
8099
8099
8099
8099
8099
8099
1959
SUBJECT INDEX
S-2l
TRANSMISSION, INTERNEURONE
indolylethylpyridines
aephenesin
TRANSMISSION, NEUROMUSCULAR
anticholinergic agents
antidromic discharge
blocking agents
cat sciatic-gastrocnemius
8143 8144
chloralose pretreatment
contractile response
direct stimulation
indirect stimulation
3-OH PTEA
oxypanamine
oxyphencyclimine
postjunctional membrane
presynaptic blockade
presynaptic response
repetitive activity
stimulation frequency
twitch tension potentiation
Win 4981
TRANSMISSION, SYNAPTIC
neurohumoral agents
spinal cord reflexes
vascular effects
TRICYCLAMOL
atropine compari son
gastric secretion
inhibitory effect
oral administration
spasmolytic effect
TRIFLUOPERAZINE
fighting episodes
footshock response
suppressive effect
TRIHYDROXYBENZENES
blood pressure
ventricular contractile
TRIPELENNAMINE
antihistaminic activity
C14-labeled
distribution
excretion
glucuronide formation
hydroxylation
liver tissue
metabolism in vitro
metaboli tea
urinary C14
d-TUBOCUB.ARINE
8115 acute toxicity
8115 cat sciatic-gastrocnemius
choline antagonism
contractile response
decamethonium interaction
decamethonium potentiation
direct muscle stimulation
edrophonium antagonism
head-drop assay
indirect muscle stimulation
neostigmine antagonism
8130
neuromuscular blockade
neuromuscular blocking action
oxypanaminesuccinylcholine interaction
time course
d-tubocurarine pretreatment
Win 4981 comparison
TYRAMINE
pressor response
reserpine pretreatment
URETHANE
action duration
megimide antagonism
URINARY CALCULISM
human subjects
salicylamide metabolites
salicylamide prevention
VAGUS NERVES
atropine comparison
inhibitory effects
oxyphencyclimine
VASODEPRESSOR AGENTS
ormosia panamensis
oxypanamine
VASODILATATION, LOCAL
cardiodynainic a
coronary arteries
coronary blood flow
intracoronary injection
NRD -2 55
papaverine
VASOPRESSIN
human subjects
morphine influence
plasma hydrocortisone levels
8122
8122
8122
8106
8106
8106
8106
8106
JANUARY FEBRUARY MARCH APRIL
Entry Entry Entrl Entry
8099 1 8111 97 8123 185 8136 275
8100 14 8112 105 8124 194 8137 283
8101 19 8113 Ill 8125 198 8138 287
8102 23 8114 116 8126 202 8139 295
8103 28 8115 122 8127 208 8140 303
8104 35 8116 128 8128 213 8141 309
8105 40 8117 137 8129 218 8142 316
8106 49 8118 142 8130 227 8143 323
8107 55 8119 150 8131 230 8144 330
8108 66 8120 159 8132 237 8145 339
8109 73 8121 168 8133 241 8146 347
8110 85 8122 178 8134
8135
248
252
8147 353
SUBJECT INDEX
VOL. 125
S-22
VAS -VER
VASOPRESSOR AGENTS
differential activity
reserpine pretreatment
sympathomimetic amines
VERATRINE RESPONSE
erythrophleum alkaloids
frog sartorius
VERATRUN ALKALOIDS
erythrophleum alkaloids
frog sartorius
veratrine response
Index to Pages
VOLUME 125, 1959
8132
8136
8143
8120
8139
8116
8141
8117
8142
8139
8140
8136
8139
8109
Schanker L S
8135 Schneider J A
8144 Schoolar J C
Scott E C
8128 Seifter J
8135 Shanes A M
8121 Sherrod T R
8104 Smith C M
8141 Stabenau J R
8119 Steck E A
Sullivan L P
Swan K
Swanson E E
Sydow V L
8146
8108
8112
8103
8131
8117
8138
8147
Talbot M H
Tedeschi D H
Tedeschi R E
Thompson W L
Tocco D J
Trendelenburg U
Urban C
8145
8147
81388121
8138
8102
8118
8141
8103
8144
8106
8132
8125
Walkenstein S S
Walton R P
8115 Walton R P Jr
8134 Way E L
Weinman E 0
8144 Weise V K
8133 Wells J B
8138 Werner C
8122 White H D
8100 White R P
8122 Wilde W S
8125 Wood W C
Woods L A
8109
Zapata-Ortiz V
Zetler C
8123 Zubrod C C
8124
8099
8113
8143
8102
1959
AUTHOR INDEX
A-l
Alphin R S
Axeirod J
Baer J E
Barlow C F
Bender C H
Berman D A
Berman M D
Beyer K H
Blackmore W P
Brodie B B
Brooks A V
Butler W M Jr
8110
Cafruny E
Campos -I turn zaga
A
Castro de Ia Mata
R
Chen K K
Cochin J
Cook L
Costa E
Covin J M
Cull K M
Cullumbine H
Daigneault E A
Dandiya P C
Dickison H L
Domino E F
Doran K M
Doran W J
Dresel P E
8127
Duvall R N
Eddy N B
Evans F T
Farah A
Fellows E J
Finkelstein N
Flacke W
Forsaith J
Foye W 0
Geissman T A
George R
Cesler R N
Gibson W R
8108 Hendershot L C
8112 Hogben C A M
Hoppe J 0
Irwin R L
John E R
Johnson C A
Kien C A
Killam K F
Kissel J W
Kletzkin M
Kruse R
Kuperman A
8141 Lange W E
Lasher A V
8146 Lee H M
Lee L E Jr
Leidy H L
Lin T M
McDonald R K
Malvin R L
Mattis P A
Maxwell R A
Mellett L B
Mirsky J H
Moran N C
8110
Mucha A
Nickerson M
Niesler V N
O’Dell T B
8125 Owen J E Jr
8114 P’an S Y
8133 Patrick R W
Pindell M H
Plummer A J
Pohland A
Povalski H
Prien E L
Quinn C P
8110
RaIl D P
8124
Riker W F Jr
Robbins E B
Roberts J
Roth L J
Vander A J
8103 Verhave T
Vick R L
8118
8144
8125
8143
8100
8114
8139
8108
8133
8101
8103
8122
8111
8115
8109
VOL. 125
8119
8134
8119
8116
8136
8144
8116
8100
8137
8142
8128
8130
8123
8143
8101
8104
8102
8129
8125
8103
8103
8126
8136
8107
8130
8101
8134
8105
8137
8126
8126
8113
8099
8133
8120
8119
8115
8145
8101
8102
8111
8146
8131
8123
