Acoustic Neuroma
Transcript of Acoustic Neuroma
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ACOUSTIC NEUROMA
dr Ika Yuliartanti.,SpTHT-KL.,M.Kes
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INTRODUCTION Represent 10% of all intracranial tumors. Vestibular schwannomas (=acoustic
neuromas) 78% of CPA vestibular branch of the 8th cranial nerve.
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STAGING
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VESTIBULAR SCHWANOMA Autopsy series: 1,7% to 2,7% of
undiagnosed & clinically silent Incidence of 0.7 to 1/100.000 population arise from the vestibular segment of the
8th nerve from schwann cells (the most commonly)
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TUMOR BIOLOGY
The molecular genetics:• Occur as a sporadic variety (95%)• Bilateral in case of type 2 neurofibromatosis• Younger patient & in association with other
intracranial meningioma & spinal cord tumor.• Genetic defect: autosomal dominant & long
arm of chromosome 22.
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Symptoms
Related to tumor size & growth. Intracanalicular: HL, tinnitus, & vestibular
dysfunction CPA: Severe HL & dysequilibrium Brainstem: Midfacial hypesthesia,
hydrocephalus, headache, & visual loss.
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Hearing Loss
Unilateral HL (> 85%) Loss of speech discrimination (the most
common) Tinnitus (second) : (56%) unilateral vascular occlusion of the labyrinthine
artery
Sudden SNHL (26%)
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Vestibular symptoms
Dysequlibrium 56% Vogue Transientlight headness Meniere’s disease (spread into labyrinth)
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Other symptoms
Facial numbness N V-2 (maxillaris) Occular symptoms diplopia or visual
blurring Cerebellar involvement late
Incoordination, fall toward the affected side
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Audiometric testing65% High tone SNHL & 5% normal
hearingSpeech discrimination scoreAcoustic-reflex threshold & decayABR (the most sensitive & specific)
DIAGNOSTIC TESTING
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VESTIBULAR TESTING
ENG Dynamic postulography Rotary chair testing Caloric test Spontaneous nystagmus large tumor
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IMAGING
Plain film CT scan MRI
contrast iophendylate
contrast air cisternography
Gadolinum DTPA
63% accurate a convex bulge of a mass
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MANAGEMENT
1. Preserve life2. Avoid serious neurologic sequele3. Complete tumor removal4. Preserve facial nerve function5. Preserve hearing
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SURGERY
Primary treatment A team: a neurosurgeon & neurootologist Use of microsurgical technique &
intraoperative monitoring of the facial nerve
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Middle Cranial Fossa Approach
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Retrosigmoid Approach
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Complications:
Facial nerve paralysis (the most common)
Leakage of LCS (4% to 14%) Meningitis rare