aclearoutcomein - The Journal of Nuclear...
Transcript of aclearoutcomein - The Journal of Nuclear...
SIEMENS
The E.CAM offers extensive cardiac-specificassessment tools that increase clinical qualityand accuracy. The result...an unsurpassed levelof clinical confidence.
Featuring unique clinical solutions...•Profile non-uniform attenuation correction•Efficient comprehensive review displays•Advanced telemedicine and connectivity packages•Cedars gated SPECTquantification
•Emory cardiac quantitative 'toolbox'- EF,volumes and mass- Wall motion analysis- Defect extent/reversibility maps- Transient ischemie dilatation ratio- 3D cardiac displays- Coronary artery overlays/image fusion
When it comes to clear outcomes, the E.CAMdelivers a level of performance second to none.
a clear outcome in
Siemens Medical Systems, Inc. •North and South America 847.304.7700 •Canada 905.819.8000 •Europe 49.9131.84.6685 •
Asia and Pacific Rim 81.3.5423.4066 •E-mail: [email protected] •Web site: http://www.sms.siemens.com/nmg
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I» OProfile Attenuation Correction Emory Cardiac Toolbox Cedars Gated SPECTQuantification
I I I
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Xian Liya Electronic Instruments Co., Ltd.No. 11, East Xiao Zhai Rd.Xian, Shaanxi ProvincePeoples Republic of China
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See your way clear
Decisive information keepsyou on course
Guiding you to optimal interventionfor neuroendocrine tumors•Somatostatin receptor scintigraphy with OctreoScan
detects and localizes primary tumors and metastaticspread often missed by conventional imaging(sensitivity varies 61%-100%, depending ontumor type).'
•Whole-body scanning can more definitively confirmthe extent of disease.
•You are better able to
- stage the patient- determine diagnostic work-up
- avoid unnecessary procedures
- select optimal treatment
- assesssurgical candidates
- evaluate response to treatment
Transient adverse effects including dizziness,fever, flush, headache, hypotension, changesin liver enzymes, joint pain, nausea, sweating,and weakness were observed in less than 1%of 538 patients during clinical trials.
Please see the prescribing information for specialconsiderations regarding patients receiving total
acetate therapy and patients with insulinoma orimpaired renal function.
Theacceptedstandardfor CEP*tumors
An emergingchoice forsmall cell lung cancer
'Castnxntero-pancreaticneuroendocrinetumofs
OCTREOSCAN
Mr.i.sr sec .¡tlj.ici-nl/).«(•/'or hriri sunmwry (>/'/jr<wri/>/n# intorm.ttion.
"OCTREOSCAN*KitforthePreparationofIndiumIn-IllPentetreotide
BRIEF SUMMARY OF
PRESCRIBING INFORMATION
OctreoScan'isakitlorthepreparationolindiumln-111pentetreotide,adiagnosticradio-pharmaceutical.It isakitconsistingol twocomponents:1) A 10-mLOctreoScanReactionVialwhichcontainsa lyophilizedmixtureol 10ugpentetreotide.2) A 10-mLvialofIndiumln-111ChlorideStenleSolution.Indiumln-111pentetreotideispreparedbycombiningthetwokitcomponents.
INDICATIONSANDUSAGEIndiumln-111pentetreotideisanagentforthesctntkjraphiclocalizationol primaryandmetastaticneuroendocrinetumorsbearingsomatostatinreceptors.
CONTRAINDICATIONSNoneknown
WARNINGSDONOTADMINISTERINTOTALPARENTERALNUTRITION(TPN)ADMIXTURESORINJECTINTOTPNINTRAVENOUSADMINISTRATIONLINES;INTHESESOLUTIONS,ACOMPLEXGLYCOSYLOCTREOTIDECONJUGATEMAYFORM.Thesensitivityofscintigraphywithindiumln-111pentetreotidemaybereducedinpatientsconcurrentlyreceivingtherapeuticdosesofoctreolideacetate.Considerationshouldbegiventotemporarilysuspendingoctreotideacetatetherapybeforetheadministrationofindiumln-111pentetreotideandtomonitoringthepatientforanysignsofwithdrawal.
PRECAUTIONSGeneral
1.Therapywithoctreotideacetatecanproduceseverehypoglycémieinpatientswithinsulinomas.Sincepentetreotideisananalogofoctreotide,anintravenouslineis recommendedinanypatientsuspectedofhavinganinsulinoma.Anintravenoussolutioncontainingglucoseshouldbeadministeredjustbetöreandduringadministrationofindiumln-111pentetreotide.2.Thecontentsofthetwovialssuppliedwiththekitareintendedonlyforuseinthepreparationofindiumln-111pentetreotideandareNOTtobeadministeredseparatelytothepatient.3.Sinceindiumln-111pentetreotideiseliminatedprimarilybyrenalexcretion,useinpatientswithimpairedrenalfunctionshouldbecarefullyconsidered.4 Tohelpreducetheradiationdosetothethyroid,kidneys,bladder,andothertargetorgans,patientsshouldbewellhydratedbeforetheadministrationofindiumln-111pentetreotide.Theyshouldincreasefluidintakeandvoidfrequentlyforonedayafteradministrationofthisdrug.Inaddition,it is recommendedthatpatientsbegivenamildlaxative(e.g.,bisacodylorlactulose)beforeandafteradministrationofindiumln-111pentetreotide(seeDosageandAdministrationsection).5.Indiumln-111pentetreotideshouldbetestedforlabelingyieldofradioactivitypnortoadministration.Theproductmustbeusedwithinsixhoursofpreparation.6.Componentsofthekitarestenleandnonpyrogenic.Tomaintainsterility,it isessentialthatdirectionsarefollowedcarefully.Aseptictechniquemustbeusedduringthepreparationandadministrationofindiumln-111pentetreotide.7.Octreotideacetateandthenaturalsomatostatinhormonemaybeassociatedwithcholelithiasis,presumablybyalteringfatabsorptionandpossiblybydecreasingmotilityofthegallbladder.Asingledoseofindiumln-111pentetreotideisnotexpectedtocausecholelithiasis.8.Aswithanyotherradioactivematerial,appropriateshieldingshouldbeusedtoavoidunnecessaryradiationexposuretothepatient,occupationalworkers,andotherpersons.9.Radiopharmaceulicalsshouldbeusedonlybyphysicianswhoarequalifiedbyspecifictraininginthesafeuseandhandlingofradionuclides.
Carcinoqenesis.Mutagenesis.Impairmentof FertilityStudieshavenotbeenperformedwithindiumln-111pentetreotidetoevaluatecarcinogenicpotentialoreffectsonfertility.Pentetreotidewasevaluatedformutagenicpotentialinaninvitromouselymphomaforwardmutationassayandaninvivomousemicronucleusassay;evidenceofmutagenicitywasnotfound.
PregnancyCategoryCAnimalreproductionstudieshavenotbeenconductedwithindiumln-111pentetreotide.It isnotknownwhetherindiumln-111pentetreotidecancausefetalharmwhenadministeredtoapregnantwomanorcanaffectreproductioncapacity.Therefore,indiumln-111pentetreotideshouldnotbeadministeredtoapregnantwomanunlessthepotentialbenefitjustifiesthepotentialrisktothefetus.
NursingMothersIt isnotknownwhetherthisdrugisexcretedinhumanmilk.Becausemanydrugsareexcretedinhumanmilk,cautionshouldbeexercisedwhenindiumln-111pentetreotideisadministeredtoanursingwoman.
PediatrieuseSafetyandeffectivenessmchildrenhavenotbeenestablished.
ADVERSEREACTIONSThefollowingadverseeffectswereobservedinclinicaltrialsata frequencyoflessthan1%of538patients:dizziness,fever,flush,headache,hypotension,changesinliverenzymes,jointpain,nausea,sweating,andweakness,Theseadverseeffectsweretransient.Alsoinclinicaltrials,therewasonereportedcaseofbradycardiaandonecaseofdecreasedhematocntandhemoglobin.Pentetreotideisderivedfromoctreotidewhichisusedasa therapeuticagenttocontrolsymptomsfromcertaintumors.Theusualdoseforindiumln-111pentetreotideisapproximately5 to20timeslessthanforoctreotideandissubtherapeutic.Thefollowingadversereactionshavebeenassociatedwithoctreotidein3%to10%ofpatients:nausea,injectionsitepain,diarrhea,abdominalpain/discomfort,loosestools,andvomiting.Hypertensionandhyper-andhypoglycemiahavealsobeenreportedwiththeuseofoctreotide.
DOSAGEANDADMINISTRATIONBeforeadministration,apatientshouldbewellhydrated.Afteradministration,thepatientmustbeencouragedtodnnkfluidsliberally.Eliminationofextrafluidintakewillhelpreducetheradiationdosebyflushingoutunbound,labelledpentetreotidebyglomerularfiltration.It isalsorecommendedthatamildlaxative(e.g.,bisacodylorlactulose)begiventothepatientstartingtheeveningbeforetheradioactivedrugisadministered,andcontinuing
for48hours.Amplefluiduptakeisnecessaryduringthisperiodasasupportbothto renaleliminationandthebowel-cleansingprocess.Inapatientwithaninsulinoma,bowel-deansingshouldbeundertakenonlyafterconsultationwithanendocrinologist.Therecommendedintravenousdosetorplanarimagingis 111MBq(3.0mCi)ofindiumln-111pentetreotidepreparedfromanOctreoScankit.TherecommendedintravenousdoseforSPECTimagingis222MBq(6.0mCi)ofindiumln-111pentetreotide.
Thedoseshouldbeconfirmedbyasuitablycalibratedradioactivityionizationchamberimmediatelybeforeadministration.Aswithallintravenouslyadministeredproducts.OctreoScanshouldbeinspectedvisuallylorpaniculatematteranddiscolorationpriortoadministration,wheneversolutionandcontainerpermit.Preparationscontainingpaniculatematterordiscolorationshouldnotbeadministered.Theyshouldbedisposedofinasafemanner,incompliancewithapplicableregulations.Aseptictechniquesandeffectiveshieldingshouldbeemployedinwithdrawingdosesforadministrationtopatients.Waterproofglovesshouldbewornduringtheadministrationprocedure.DonotadministerOctreoScaninTPNsolutionsorthroughthesameintravenousline.
RadiationDoslmelryTheestimatedradiationdoses'totheaverageadult(70kg)fromintravenousadministrationof111MBq(3mCi)and222MBq(6mCi)arepresentedbelow.TheseestimateswerecalculatedbyOakRidgeAssociatedUniversitiesusingthedatapublishedbyKrenning,etal.'
EstimatedAbsorbedRadiationDosesafterIntravenousAdministrationof Indiumln-111Pentetreotide'toa70kgpatient
| PLANARSPECT09»_jHHKidneysLiverSpleenUterusOvariesTestesRed
MarrowUrinary
BladderWaiGl
TractStomach
Wall
SmallIntestineUpper
LargeIntestineLower
LargeIntestineAdrenalsThyroidEffective
Dose'Equivalent54.1612.1573.866.344.892.903.4630425.874.785.807.737.557.43mSv/111MBqrads/3mCi
j mGy/222MBq ;rarJsfômCi5.42Ì227.390.630.490.290.353.04O.S70.48MB0.770.760.74••-
rem/3mCi108.32
24.31147.7312.679.795.806.9160.4811.349.5811.5915.4615.1114.86
mSv/222MBq10.83
2.4314.771.270.980.580.696.051.130.961.161.551.511.49rem/8mCi
a13.03
1.30 26.06 2.61
1.Valueslistedincludeacorrectionforamaximumof0.1%indiumln-114mradiocontaminantatcalibration.2.E.P.Krenning,W.H.Bakker.PPM.Kooij,W.A.P.Breeman,H.Y.Oei,M.deJong,J.C.Reubi,T.J.Visser,C.Bruns,D.J.Kwekkeboom,A.E.M.Reijs,P.M.vanHagen,J.W.Köper,andS.W.J.Lamberts,"SomatostatinReceptorScintigraphywithlndium-111-DTPA-D-Phe-1-OctreotideinMan:Metabolism,DosimetryandComparisonwithlodine-123-Tyr-3-Octreotide,"TheJournalofNuclearMedicine,Vol.33,No.5,May1992.pp.652-658.
3.Assumes4.8hourvoidingintervalandInternationalCommissiononRadiologicalProtection(ICRP)30modelforthegastrointestinaltractcalculations.4.Estimatedaccordingto ICRPPublication53.
i
HOWSUPPLIEDTheOctreoScankit,NDC0019-9050-40,issuppliedwiththefollowingcomponents:1. A10-mLOctreoScanReactionVialwhichcontainsa lyophilizedmixtureof:
(i) 10ugpentetreotide[N-(diethylenetriamine-N,N.N'.N"-tetraaceticacid-N"-acetyl)-D-phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyt-L-lysyl-L-threonyl-L-hemicystyl-L-threoninolcyclic(2-»7)disulfide).(alsoknownasoctreotideDTPA),
(ii) 2.0mggentisicacid [2.5-dihydroxybenzoicacid],(mi4.9mgtrisodiumcitrate,anhydrous,iiv)0.37mgcitricacid,anhydrous,and(v)10.0mginositol.
Beforelyophilizalion,sodiumhydroxideorhydrochloricacidmayhavebeenaddedforpHadjustment.Thevialcontentsaresterileandnonpyrogenic.Nobacteriostaticpreservativeispresent.2.A 10-mLvialofIndiumln-111ChlorideSterileSolution,whichcontains1.1mLof111MBq/mL(3.0mCi/mL)indiumln-111chloridein0.02NHCIattimeofcalibration.Thevialalsocontains'ernechlorideataconcentrationof3.5ug/mL(ferricion.1.2ug/mL).Thevialcontentsaresterileandnonpyrogenic.Nobacteriostaticpreservativeispresent.Inaddition,thekitalsocontainsthefollowingitems:(1)a25Gx5/8"needle(B-DMonoject)usedtotransferIndiumln-111ChlorideSterileSolutiontotheOctreoScanReactionVial.(2)apressuresensitivelabel,and(3)apackageinsert.
IALLINCKRODT
Mallinckrodt Inc.,Mallinckrodt Nuclear Medicine Division
P.O. Box 5840St. Louis, MO 63134
1. Termanini B, Cibril F, Reynolds JC, et al. Value of Somatostatin Receptor Sciniigraphy: A Prospective Studyin Gastrinoma of its Effect on Clinical Management. G.isfroenfero/cgy1997;112:335-337.
©1997MallinckrodtInc. MI22701
Circle Reader Service No. 110
12/97
Nuclear Medicine Self-Study Programs in Cardiology
Renew Your Perspective on NuclearMedicine Cardiology with the SNM's
All-New Self-Study Series
NUCLEAR MEDICINE:
CARDIOLOGY
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Whether you're a nuclear medicine resident preparing for your
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Topic 1: Physical and Technical Aspects ofNuclear Cardiology (October 1997)Contributors: Ernest Garcia, MD, Elias
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Keep Current in One ofNuclear Medicine's FastestGrowing Areas—Oncology
NUCLEAR MEDICINE:
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Management of the cancer patient has significantly grown withbetter diagnostic techniques and chemotherapeutic agents. Learnabout these exciting advances in nuclear oncologie imaging withthe Self-Study Program series in Oncology. These Self-StudyPrograms offer an innovative package and approach to ensurethat you receive timely, targeted materials as soon as they're
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Topic Booklet 5: NonantibodyCancerTherapy (1999)ISBN: 0-932004-63-6
Topic Booklet 6: AntibodyCancerTherapy(1999)ISBN: 0-932004-64-4
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To order, simply contact SNM's book distributor, Matthews Medical Books, at their toll-freenumber (800) 633-2665 (non-U.S. 314-432-1401), or Fax: (314) 432-7044). If you chooseto order the complete series, please have yourcredit card number ready when callingMatthews Medical Books. Each topic bookletwill be automatically sent to you as they arereleased. Your credit card will only be chargedonce a booklet is ready for shipping.
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For More Information...Please visit the Society of Nuclear Medicine Home Page at wu-w.snm.org or call
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What does the future hold for the practice of nuclear medicine? Where will today's
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Kates Before 1/8/99 On/After 1/8/991Physicians/ScientistsMembersNonmembersSI95.00$260.00$245.00$305.00TechnologistsMembersNonmembersStudentsS100.00S135.00S75.00S
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The SNM Ph.Program is a self-assessment program for physicians. Each
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This activity was planned and produced in accordance
American College of Nuclear Physicians
WorkingForYou&YourPracticeFor25Years!
Since 1974, the American College of Nuclear Physicians, comprised of physicians, scientists andcoporate members, have been dedicated to enhancing the practice side of Nuclear Medicine
through the study, education and improvement of clinical practice.
PromotingQualityof PatientCare•Prepare for JCAHO, State and NRC
inspections with our QA Programs:
PracticeAccreditation Program:Compare your departments's imaging
capabilities with a nationalbenchmark;
Proficiency TestingProgram: Helps youdocument and improvethe qualityof your facility.
Legislative&ReimbursementUpdates•Have a voice in policy
and legislation;
Nuclear Physicians
ANNIVERSARY
Keep up with HCFA.
ProvidingNetworkingOpportunities•Share information with your peers at our
Annual & Fall Meetings;
•Participate in ACNP Committees;
Play a leadership role in the
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SupplyingInformation&Education•Earn CME credits at
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Keep up with our
Practice enhancement
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American College of Nuclear Physicians4400 Jenifer Street NW, Suite 230, Washington DC 20001Phone 202-244-7904»Fax202-244-7355»Pleasevisit our website - www.acnp.com
46th Annual Meeti,LOS N G E L E S CALIFORNIA
June 6 -10,1999
INQUIRIES:Society of Nuclear MedicineDepartment: Meeting Services1850 Samuel Morse DriveReston, VA 20190Phone: (703) 708-9000 x229Fax: (703) 709-9274
www.snm.org
LOCATION:Los Angeles Convention Center1201 South Figueroa StreetLos Angeles, GA 90015
DEADLINES:Pre-Registration Ends:
Last Day for Housing Reservations:Abstract Submission Deadline:
April 29, 1999April 29, 1999January 8, 1999
REGISTRATION FEES:CategoricalSaturday, .June5, 1999 Prc-Registration On-SiteMember 8115 8135Non-Member 8145 8165
(Boxed lunch is provided for the Saturday Categorical only,
the cost of which is included in the fee)
CategoricalsSunday, June 6, 1999MemberNon-Member
Prc-RcgistrationS1008130
On-SiteS120«150
Continuing EducationMonday, June 7, 1999 through Thursday, June 10, 1999
Member Pre-Registration On-SitePhysician/Scientist/Pharmacist S335 S395Technologist S205 8255
Non-MemberPhysician/Scientist/Pharmacist 8530 8590Technologist 8395 8450
Companion S55 S55
EXHIBITS:Monday, June 7, 1999 through Thursday, June 10, 1999Exhibit space is 821.50 per square foot.Contact Jane Day [email protected] for further information.
HOW TO OBTAIN PRE-REGISTRATIONAND HOUSING FORMS:1. The SNM Web Site, www.snm.org. starting January2. Fax-On-I)emand°, starting January
3. The Journal of Nuclear Medicine, February Issue4. The Journal of Nuclear Medicine Technology, March Issue
HOW TO OBTAIN A FREE COPY OFTHE SOFTWARE THAT YOU WILLNEED TO SUBMIT YOUR ABSTRACT:1. DOWNLOAD Submitter Assistant Software for the PC/Macfrom the SNMWeb Site at www.snm.org -or-
2. REQUEST a copy of the Submitter Assistant on diskette fromMedical Support Systems (MSS) at:
Attn: Submitter Assistant RequestSociety of Nuclear Medicine1000 Massachusetts Avenue, 3rd FloorCambridge, MA02138-5394
USA
Phone: (800) 375-2586 (USA), (617) 492-0509 (International)FAX:(800) 830-2586 (USA), (617) 876-5351 (International)E-mail: [email protected]
Please specify PC or Macintosh.
* Fax-on-I)emand is <inautomated system that faxes you thoseportions qf the Annual Meeting Preview you request. Ifyou do notknow exactly which ¡Mirtinayou would like to receive (or what isavailable), you can refluent an index of documents when prompted bythe system.
WHERE DO YOU FIT IN?
WHAT IS THE UA DATA BASE?The Commission on Health Care Policy andPractice in conjunction with the SNMTechnologist Task Force on Utilization Data, hasdeveloped a quarterly survey on SNM's web
site. Participants enter data quarterly.The website's data entry form will collect infor
mation from nuclear medicine practitioners tocompile a utilization analysis database.
The database contains information on:•Facility type and location
•Active general medicine and surgical beds
•Outpatient encounters (visits)
•Physician, technologist and clerical FTEs
•Planar, SPECT, PET Hybrid gamma cameras
and PET scanners•Inpatient and outpatient procedures for a
selected set of commonly used nuclear medicine CPT-4 codes
WHY SHOULD YOU PARTICIPATE?Participants receive standard reports on utilization by procedure, place of service, type ofpatient, etc.
Participants will be able to compare their facilitydata with others in the region and with thenational (global) averages.
Subscribers may query reports on-line or
receive printed reports quarterly via mail.This is a free service. As long as you input yourdata quarterly, you will be able to obtain dataand reports.
All information is confidential.For more information or to participate in thisprogram, contact UA ^^^^Project Coordinator at •fpT| UTILIZATION(703) 708-9000 x255 or ¡DATABASEe-mail: [email protected]. I b ••ANALYSIS
AN N O U N CI N G
TheAmericanBoardof
ScienceInNuclear
Medicine1999
CertificationExamination
The1999examinationwillbegivenSunday,June6,1999inLosAngeles,CAinconjunctionwiththe46thAnnualMeetingoftheSocietyofNuclearMedicine.The examination is written and consists of two parts —
Part One (3.5 hours) assesses knowledge of basic aspects of NuclearMedicine Science.
Part Two (2.5 hours) examines in depth the knowledge of apredetermined subspecialty area of the candidate's choice including:
•Nuclear Medicine Physics and Instrumentation
•Nuclear Pharmaceutical Science and Radiochemistry
•Radiation Protection
Completed Applications must be postmarked by March 12,1999.The examination fee is $650 ($550 refundable if you do not qualify).
For applications and more information, please contact:ABSNM Exam CoordinatorAmerican Board of Science in Nuclear Medicinec/o The Society of Nuclear Medicine1850 Samuel Morse Drive, Reston, Virginia 20190-5316Tel: (703) 708-9000, ext. 227 •Fax: (703) 708-9013
1ère
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The new, third edition of the widely popular SPECT: APrimer is now available from Matthews Medical Booksat the toll-free number below.
Substantially updated and expanded throughout, the third editionincludes even more basic information essential to the technologistworking in day-to-day clinical settings.
The new SPECT Primer features an enhanced section on ClinicalApplications, incorporating the latest and most widely acceptedfundamental knowledge in the field, with, three all-new chapters
on Acquisition Devices, Processing Devices, and ClinicalIndications. And in every chapter, you'll find expanded material to
help nuclear medicine professionals who use SPECT perform atpeak.Whether you're a working technologist, teacher, or student, the
new edition of SPECT:A Primer is a must for your clinical library.No other text available brings together—clearly and authoritatively—theessential information you need to understand and useSingle Photon Emission Computerized Tomography.
Call toll-free to order your copy today—$30.00members/$40.00 nonmembers.
Matthews Medical Books •800-633-2665 •(Non-U.S., call 314-432-1401)
Do you know the most effective and efficient wayto perform a myocardial perfusion study?
How does your procedure for performing renal studies for renovas-cular hypertension compare withthe procedure recommended byleading nuclear medicine experts?
How should you modify yourprocedures for adult patientswhen they are performed inpediatrie patients?
The answers to these questions and more may
be found in the 1997 Society of Nuclear Medicine
Procedure Guidelines Manual. This publication will help
you achieve high quality nuclear medicine studies to insure that your
patients get the treatment they deserve.This informative and useful reference tool
is now available for only $20.00. To order your copy contact Marie Davis at(703)708-9000 x2SO or via email at [email protected]
CONTENTS INCLUDE
PROCEDURE GUIDELINE DEVELOPMENT PROCESS
CARDIAC GUIDELINESGuideline for Myocardial Perfusion ImagingGuideline for Gated Equilibrium RadionuclideVentriculography
ENDOCRINE GUIDELINESGuideline for Thyroid Uptake Measurement
Guideline for Thyroid ScintigraphyGuideline for Extended Scintigraphy for Differentiated
Thyroid Cancer
Guideline for Parathyroid Scintigraphy
GASTROINTESTINAL GUIDELINESGuideline for Hepatobiliary Scintigraphy
Guideline for Hepatic and Splenic ImagingGuideline for C-14 Urea Breath Test
GENERAL GUIDELINESGuidelines for Guideline Development
Guideline for General Imaging
Guideline for Imaging With Radiopharmaceuticals
GENITOURINARY GUIDELINESGuideline for Diagnosis of Renovascular Hypertension
INFECTION GUIDELINESGuideline for Gallium Scintigraphy in InflammationGuideline for In-1 I I Leukocyte Scintigraphy for Suspected
Infection/InflammationGuideline forTc-99m Exametazime (HMPAO) Labeled Leukocyte
Scintigraphy for Suspected Infection/Inflammation
NEUROLOGY GUIDELINESGuideline for Brain Perfusion Single Photon Emission Computed
Tomography (SPECT) Using Tc-99m Radiopharmaceuticals
ONCOLOGY GUIDELINESGuideline for Gallium Scintigraphy in the Evaluation of Malignant
DiseaseGuideline for Tumor Imaging Using F-18 FDG
Guideline for Bone Pain Treatment
PEDIATRIC GUIDELINESGuideline for Pediatrie Sedation in Nuclear Medicine
Guideline for Radionuclide Cystography in Children
Guideline for Diuretic Renography in Children
Guideline for Renal Cortical Scintigraphy in Children
PULMONARY GUIDELINESGuideline for Lung Scintigraphy
SKELETAL GUIDELINESGuideline for Bone Scintigraphy
APublicationoftheSocietyofNuclearMedicine
DIAGNOSTICPATTERNSINNUCLEARMEDICINE
Authors: Edward B. Silberstein, MDJohn G. McAfee, MDAndrew P. Spasoti
This reference book provides a complete list ofdifferential diagnoses for virtually every patterndescribed in modem nuclear medicinescintigraphy, including the latest findings innuclear cardiology, PET,antibody andsomatostatin receptor imaging. A full list of alldiagnostic patterns reported for every organsystem is given. Pharmacologie effects onlabeling and distribution are fully described.
Diagnostic Patterns in Nuclear Medicine assists inimage interpretation by providing completediagnoses for every scintigraphic pattern. Allentries are documented by published references.Organization by organ system provides an easy-to-fìnd,detailed differential diagnosis.
The clinician simply looks up any scintigraphicfinding to determine possible causes of thatfinding, ranked in order of probability, makingDiagnostic Patterns in Nuclear Medicine the mostcomplete referenced diagnostic guide available.
ISBN: 0-932004-69-5
Price: $45 (members);$63 (nonmembers).
First-pass radionuchde
MTTERNSIN NUCLEAR
1. Superior vena cavaa. obstruction
sawardB-Sibastein
Jthn G. McAfee
Andrew P.
Table of ContentsPart I: CardiovascularSystemPart II: Central Nervous SystemPart III: EndocrineSystemPart IV: The EyePart V: GalliumImagingPart VI: GastrointestinalSystemPart VII: GenitourinarySystemPart VIII: HématologieStudies/DiseasesPart IX: Peri-Diaphragmatic Disease
Part X: PulmonarySystemPart XI: SkeletalSystemPart XII: Tumor/InflammationImaging (Non-Gallium, Non-Leukocyte)
For more information on SNM books, visit our Web site:
http://www.snm.org
To order, simply callMatthews Medical Books at
their toll free number:
800-633-2665Non-U.S. 314-432-1401 or
FAX 314-432-7044
ights! Camera! Act on yourpassion for nuclear medicine atthe Society of Nuclear Medicine's
46th Annual Meeting.
The latest developments that willkeep you at the forefront ofnuclear medicine await you.Here you will findcomprehensive continuingeducation sessions and refreshercourses on the latest nuclearmedicine issues that willencompass practical and basicaspects of nuclear medicine
procedures in the management ofclinical dilemmas and their cost-
effectiveness. Also included willbe courses pertaining to the state-of-the-art in instrumentation and
radiopharmaceuticals, andupdates on new regulations.These courses will also emphasizethe practical roles of SPECT andPET in a variety of diseaseentities such as myocardialperfusion, brain perfusion, cancerdetection and staging.
The Technologist Section
June 6-10, 1999Join 7,OOO attendees from around the world at theSociety of Nuclear Medicines 46th Annual Meeting
educational program will followthe theme of diseasemanagement.
Continuing education sessionsand categorical seminars offerattendees approximately 33credit hours of AMACategory 1CME for physicians, ACPE forcontinuing pharmaceuticaleducation for pharmacists, andGEH through the VOICE programfor technologists (for coursesoffered Saturday, June 5 throughThursday, June 10, 1999).
Join us !
For further information contact the Department: Meeting Services, 703-708-9000 ext. 229, fax on demand at 888-398-7662 or
visit us at our website www.snm.org
OF NUCLEAR MEDICINE PATIENT PAMPHLET SERIES
EducateYourPatientsSNMPatient PamphletsOffer the ReassuranceYourPatients Need
Asa clinician,youknownuclear
medicineproceduresaresafe
andeffective.Butyoualsoknow
that patientsaresometimes
uneasyaboutthem.Giveyour
patientspeaceof mindbypro
vidingthemwith conciseand
thoroughinformation.Whateveryour
mostcommonlyorderedprocedure,you'll find anSNMPatientPamphlet
that will addressyour
patient educationneeds.
lucie«RitteimpsfuiOï«nma[Dimettilitati
For more information on SNMbooks, visit our Web site:
http://www.snm.org
Startwith "TheBenefitsof Nuclear
Medicine."Thispamphletdefinescom
monlyperformednuclearmedicinepro
cedures,andincludesaquestionand
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OtherPatientPamphlettopicsoffer
yourpatientsdescriptionsonspecific
exampreparations,examprocedures
andspecialinstructionsfor your
patientsto follow whentheygohome
andafter their treatment.
•NuclearMedicineBenefits
•RadioiodineTreatment•Stress-RestTest
•BrainImaging
•LiverandHepatobiliaryImaging
•BreastImaging
•BoneImaging
•RenalImagingin Children
•ProstateCancer
•OvarianandColorectalCancer
All pamphletsare40C/copy;
minimumorderof 50.
Toorderthe SNMPatientPamphletSeriescontactthe SNM's 800-633-2665
medicalfulfillment company,MatthewsMedicalBooks. Non-U.S.314-432-1401or FAX314-432-7044E-mail:[email protected]
Positions NeededPostdoctoral Fellowship in PET/SPECT/f MRIImaging
Unique opportunity for postdoctoral training in functional imaging research. Emphasis on neuropsychiatrie,psycho-pharmacologie, oncology imaging and quantification techniques. Excellent mix of clinical and basicresearch. Opportunity for fMRI/PET correlation. MD/clin-ical credentials required. May start as early as June 1999.Applications to Dean F. Wong. MD. PhD, Johns Hopkins Med Inst. Radiology-JHOC Bldg, Rm. 3245, 601N. Caroline St.. Baltimore. MD 21287-0807. E-mail:drwongferad.jhu.edu.
Faculty Position-Northeast FloridaThe University of Florida Health Science Center/Jacksonville seeks MD, BC/BE in Diagnostic Radiology, withSpecial Competency or BC/BE in Nuclear Medicine.Fringe benefits are excellent, salary is negotiable. This isa full-time faculty position in the Department of Radiology, with academic rank based on training, backgroundand experience. Send CV and references to Chairman,Search Committee. Radiology Department. 655 W. 8thSt., Jacksonville, FL 32209. Fax: (904) 549-3382.EOE/AAE.
BCIM/NMUnique practice opportunity available for expanding two-man group practice for BC IM/NM physician. Practiceresponsibilities include hospital-based and outpatient NM
facilities and private practice of IM with special emphasis on thyroid disease, osteoporosis and diabetes. Qualified applicants send CV to Carolina Nuclear Medicine,841 Heather Rd., Burlington. NC 27215.
Full-Time Nuclear PhysicianFull-time nuclear physician for a community hospitallocated an hour drive from Chicago. Modem departmentwith Picker triple- and dual-head cameras. Would prefera recently trained physician with board certification andinterest in nuclear cardiology. Please send CV to Amar-jit Kochar, MD, Departments of Pathology and NuclearMedicine, St. Mary Medical Center, 1500 S. LakeparkAve., Hobart, IN 46342. Phone: (219) 947-6266. Fax:(219)947-6306.
Nuclear Medicine ServiceDepartment of Veterans Affairs
Medical CenterDallas, TX 75216
Applications are being sought for a full-time Nuclear
Medicine Staff Physician, Veterans Affairs MedicalCenter, Dallas, TX.The position includes an academicappointment in the Department of Radiology,University of Texas Southwest Medical School.
Applications must be board eligible or board certifiedin Nuclear Medicine. Cardiac, Therapeutic and SPECTexperience as well as strong research capabilitiesrequired.
Responsibilities include teaching Radiology andNuclear Medicine residents. A CVand 3 letters of reference should be sent to: Ana Mello, MD, Chief, NuclearMedicine Service, Veterans Affairs Medical Center,4500 Lancaster Rd.,Dallas, TX 75216.
NO TELEPHONE CALLS ACCEPTED.
Equal Opportunity EmployerApplicants Subject to Drug Testing
Smoke-Free Facility
34A THE JOURNALOFNUCLEARMEDICINE•Vol. 40 •No. 1 •January 1999
Leadership in nuclear medicine...
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