About Stem Cells Use and Trends

7/27/2019 About Stem Cells Use and Trends

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Stem Cell Treatments

What is available today?


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Agenda

What is a stem cell?

Types of stem cells

How does the body naturally heal? What is Stem cell Therapy?

Risks and secondary effects

Myths of stem cells Current therapies


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A cell is the basic functional structure of

the human body

Tissue is formed by more cells

Organs are formed by more tissues

Sistems are formed by more organs

A body is formed by many systems.


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A mature cell has specific functions depending on

the organ where it belongs.

A mature cell has a limited number of replications.

Mature Cells


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What is a Stem Cell?

Is capable of reproducing itselfmany times: Produce a cell thathas identical properties as the

original.

Is capable of differentiation intoanother kind of cell. (transformationto another type of tissue).

Homing capability.

A special type of cell, referred to as a master cell.


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How does the body naturally heal?

When in balance, there is a life cycle. Stem cell is born, travels to the tissue to be worked on, differentiates

into that type of tissue (becomes tissue cell), when a cell of that tissue

dies and is discarded, the new cell replaces it.We have continuous production of stem cells.

Out of balance, accelerated damaged cells.

Could be many reasons. Body does not release enough stem cells to repair damage. Chronic disease.


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Embryonic

They are located inside the blastocyte or embryos up to 8 weeks offertilization.

Adult stem cells.

They are located all over a formed body with higher concentration on:

Cord blood and placenta

Fat Bone Marrow

Types of stem cells by source


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Totipotent

Could grow and form a complete new organism

Pluripotent

Could form any other kind of cell Multipotent

Could diferentiate only on a cell of its line.

Unipotent

Only can form one type of cell

Types of stem cells

by potential


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Why embryonic stem cells are

controversial?

Pros: They are Highly prolific- Very easy to duplicate

They are Pluripotent - Can be differentiated into all kind oftissue

Cons: Has to come from a blastocyte - Embryo

They are Pluripotent- could differentiate into unwanted kind

of tissue on unwanted locations. They are Highly prolific- risk of growing theratomas

Gene information is also transferred to recipient.

Legal issues


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Culture and differentiation from embryonic stem cell


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Adult stem cells

Pros: They are Highly prolific- but not unlimited

They are Pluripotent or multipotent

Primitive undifferentiated cells Easier access

Cons:

Limited on proliferation Limited in quantity on some areas


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Bone Marrow Stem Cell


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What is Stem Cell Therapy?

Stem cell therapy = use of stem cells to treat medical conditions.

Difference between Infusion and Transplant

Infusion:adding to your body. Reinforces your currenttissues and systems (immunologic, neurologic andmetabolic)

Transplant: replacing an organ. Usually involves anorgan transportation and storage, and an aggressivepatient preparation.


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Autologous- own tissue. Same donor and recipient.

Homologous / Allogenic- Tissues from the samespecies

HeterologousTissue from other species

Types of Transplant


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Risks and secondary effects of Stem

cell therapy infusion

Autologous Risk: Infection

Secondary effects: head ache, bruise skin.

Allogenic

Genetic Disease transmission

Low viability if not stored/processed properly

Tissue rejection

Secondary Effects: same as above and variable with thecomplications.

CAUTION: the more different the tissue is, the more

aggressive the risks are. (example: animal stem cells)


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Myths of stem cells

In the near future Stem cells will cure all and everyone! Stem cells cause theratomas.

Stem cells from your own body cannot treat your ownillness.

All Stem cells are illegal.

Stem cells therapies are super expensive, 50K+.

Stem cells from Shark cartilage are much better.

Stem cells from Placenta or Fat have 10x the number ofcells compared to bone marrow or umbilical cord.


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Conditions with the best results:

IMMUNOLOGICAL DISEASESRheumatoid Arthritis Systemic Lupus

Fibromyalgia Psoriatic Arthritis

Sjgren Syndrome Asthma

METABOLIC DISEASES

Diabetes Mellitus Renal Insufficiency

Cardiac Insufficiency Hepatic Insufficiency

NEURODEGENERATIVE DISEASES

Multiple Sclerosis Alzheimer's disease

Parkinson's disease


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Conditions with the best results:

OPHTHALMIC DISEASESMaculopathy Diabetic Retinopathy

Optic Nerve Atrophy Central Retinal Vascular Occlusion

Other:Pediatric: Muscular dystrophia Healthy Aging (Anti-aging)

Immunologic Esthetics: Face lift, Hair growth

Neurologic (Autism, Cerebral Palsy)


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Trends Bone Marrow Stem Cell Therapy

Been here for a few years and continues to grow.

Cord Blood Stem Cell Therapy

Still Being studied.

Not so regulated

Consequences because of being allogenic.

Fat tissue Stem Cell Therapy

Growing interest (easy to provide in a Drs office)

Specially for Esthetics

Embryonic Stem Cell Therapy Is going to take even longer to be useful.


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The ProcedureCase Study:

Consultation, Blood work, Specialist assessment (if needed).

Patient Preparation

Procedure:

Aspiration of Bone marrow with local anesthesia

Cell preparation, Dilution, Cell concentration

Infusion by IV and/or Catheter

Direct injection to organs, Lumbar, joints, retro bulbar, thyroid, subcutaneous,

injuries, etc.

Recovery/Observation after procedure

Usually, 3 day and 2 nights trip, but could be done in 1 day.


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Patient steps for treatment

1. Study patients condition (Questionnaire, X-Ray,MRI, blood work, reports)

2. Medical team determines best therapy for specific

case

3. Coordination and Scheduling (date of procedure,

transportation, accommodation, meals, etc.)

4. Patient travel and logistics support.

5. PROCEDURE

6. Follow up (1 day, 7, 30, 60 and 90 days)


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ProgenCell performs safe Stem cell therapies

with NO complications up to date!

In other words, ProgenCell provides

outpatient treatment to improve patients health conditions byautoinfusion of stem cells obtained from bone marrow.

Powerful, Practical and Cost Effective!


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More than 600 treatments No complications - very safe

All cases have had improvement

50% excellent results, only one case with bad resultsbecause of other factors.

Factors influencing the outcome

Bone marrow condition

Chronic Disease stage (advanced/early stage)

Multiple conditions present

Harmful habits

ProgenCell Results


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Medical Commitee Our medical staff are pioneers in stem cell therapies,with more than 10 years of experience.

The Scientific and Ethic committees are formed bydoctors with different specialties:

President of the Scientific Committee: Dr. LuisRomero

President of the Committee of Scientists: Dr. JorgeLuis Gavio

Internal Medicine: Dr. Miguel Angel Matildes

Orthopedics: Dr. Joaqun Garcia Zeevaert

Ophthalmology: Dra. Norma Nio Sulkowska

Cardiology: Dr. Hctor Soto Espinoza

Neurology: Dr Hugo Navarrete


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Facilities

ProgenCell is located just oneblock inside Mexico, at the US-MEXICO border.


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Conclusions

Stem cell therapy is:

Effective for selected cases.

Is not for everyone and cant cure all.

A new perspective in medicine.

Treatment with scientific base

Possible hope for current incurable diseases

Definitely a promising future!


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Learn more about stem cell therapies

by contacting us!

About Stem Cells Use and Trends

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