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Chapter15 Role of IT in Healthcare
V 30 April 2010
For Associates
Certificate in Healthcare and Life sciences ndash L1
2
Confidentiality statement
This document should not be carried outside the physical and virtual boundaries of TCS
and its client work locations The sharing of this document with any person other than
TCSer would tantamount to violation of confidentiality agreement signed by you while
joining TCS
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
3
Chapter 15 Role of IT in HealthCare
In this Chapter
The session discusses about the impact of IT in health care It talks about the nature and
scope of information power granted by IT It also deals with the influence of IT on the
design of healthcare systems Lastly it talks about bioinformatics
Learning Objectives
After reading this session you will know about
bull Impact of IT on healthcare
bull Impact of IT on the design of healthcare system
bull Nature and scope of information granted by IT
bull Role of IT in Life Sciences
Topics Covered
Chapter 15 Role of IT in HealthCare3
151 Introduction 4
152 Impact of IT on Healthcare 4
153 Hospital Information System 7
154 EHR (Electronic Healthcare Records) 14
155 Nature and Scope of Present Trends in IT and Health 18
1551 ITrsquos role in design of healthcare products and services 18
1552 ITrsquos impact on design of healthcare systems 20
1553 Nature and scope of information power granted by IT 20
1554 ITrsquos facilitating role in strengthening public-private partnerships 21
1555 IT-induced vulnerabilities and IT-aggravated risks 23
156 Information Technologyrsquos Role in Life Sciences Research amp Development 25
157 Bioinformatics Assists Drug Discovery and Development 27
158 The Indian Perspective 27
Summary 29
Deleted 15
Deleted 19
Deleted 21
Deleted 21
Deleted 22
Deleted 24
Deleted 26
Deleted 28
Deleted 29
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
4
151 Introduction
IT investment offers an environment for a new level of care to exist For example IT can
provide a prospect to evaluate trends that previously took much longer to identify
Enhanced information access can lead to rapid decision-making The confirmation of
better information leads to better care can be confirmed by the improvement in health
outcomes Better health outcomes include
bull diagnosing patients more accurately and quickly
bull act in accordance with patientsrsquo wishes and comforting the family
bull decreasing the number and severity of errors
bull supporting care delivery through improved access to information
Information technology (IT) has significantly reduced the costs improved the speed
and enhanced the efficiency of life sciences research and development (RampD) The RampD
in turn has established new challenges and opportunities for IT applications This cycle
has added to an entire new frontier for knowledge production For example the union
of IT and biological progresses made possible the mapping of the whole human
genome and genomes of many other organisms in just over a decade These
inventions along with the current efforts to establish gene and protein functions have
enhanced our capacity to know the root causes of human animal and plant diseases
and find new cures for the same In addition to this many future IT innovations will
likely be stimulated by the data and analysis demands of the life sciences
152 Impact of IT on Healthcare
The maximum advancements of IT will be felt on release of healthcare Some of the
futuristic happenings would include
Right now there is a clear cut difference between healthcare product manufacturers
and marketers and the healthcare delivery systems Pharmaceutical corporations
belong to the previous group and hospitalsclinics are major parts of the healthcare
delivery systems in society IT will associate the two as one leading to blurring of the
boundaries Thus we would have a future situation where Pfizer would be concerned in
storing profiles of patients in a locked web site in an electronic format accessible via a
password through internet and WAP-mobile services Thus Pfizer would help identify
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
5
cases of hyperlipidemia store e-records and provide access to these to authorized
employees
The second impact of IT would be a new type of experts or companies ndash the electronic
healthcare information providers or healthcare counsel providers These healthcare and
IT knowledgeable people would help incorporate the vast database of health disease
and treatment related information including prevention and would assist therapy
givers provide the best integrated therapy for an individualrsquos sickness condition
The third impact of IT would be in the form of Pharma companies or connected
companies generating and sustaining electronic records of genetic profiles of people
and helping therapy givers give the best treatment based on the hereditary tendencies
of the patients
The fourth impact of IT would be societal media assisted word-of-mouth propagation of
healthcare information tips and knowledge These are very dominant influencers
Information technology presents huge potential benefits to US healthcare As per the
Institute of Medicine as many as 98000 people pass away in hospitals every year from
medical errors such as wrong medications and improper identification of diseases
many of which are preventable A study conducted by the Healthcare Information
Management Systems Society found out that approximately 49 of clinical diagnostic
testing is carried out since prior test results are not available when required
Applications of IT to healthcare such as electronic healthcare records (EHRs)
computerized ordering of prescriptions and tests and updated medical information for
clinical decision support can save thousands of lives and billions of dollars by
decreasing medical faults and miscommunication
The entry of IT into the healthcare has been slow and disorganized Only 12 of
practices with smaller number of physicians have adopted EHRs The healthcare
industry expends only 2 of revenues on information technology which is much lower
than the 10 average of other information-intensive industries
The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly accepted
technical standards In spite of the efforts at the Department of Health and Human
Services (HHS) since 2004 such standards have yet to be completely developed and
extensively propagated Furthermore there is also a need of conformance testing to
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
6
make sure that product and systems meet the terms of the set HIT interoperability
standards Without these standards and conformance tests healthcare providers are
unwilling to spend in HIT systems as there is no guarantee that they will be able to
correspond with other systems
The federal governmentrsquos lead organization for the progress and spread of technical
standards the National Institute of Standards and Technology (NIST) has been
concerned with HIT standards development work since 2005 With its extensive
expertise with issues of system interoperability data security and privacy and
consensus standards development NIST is well placed to make a larger contribution to
HIT standards development work and speed the use of a national secure and
interoperable HIT system
On May 21 2007 Chairman Bart Gordon introduced HR 2406 a bill to sanction NIST to
boost its efforts in support of the incorporation of the US healthcare information
project The bill
bull Directs NIST to set up an proposal for progressing HIT integration and permits it
to support healthcare representatives and organizations and federal agencies in
developing technical roadmaps for HIT standards
bull Requires NIST to build up or take up existing technology-neutral guidelines and
standards to facilitate federal agencies to efficiently choose and exercise HIT
systems that are safe interoperable and guarantee patient privacy
bull Requires the Department of Commerce to start a Senior Interagency Council on
Federal Healthcare Information Technology Infrastructure to synchronize the
development and deployment of federal HIT systems the related technology
transfer and federal work with private HIT standards development
organizations
bull Requires NIST to institute a university funding program for multidisciplinary
research in HIT-related fields and
bull Directs the National High-Performance Computing Program to organize federal
HIT RampD programs
Though the United States is the most technologically advanced nation in the world the
US healthcare system persists to depend on pen and paper for the bulk of its
information requirements From patient medical histories to prescriptions to hospital
charts handwritten notations are the foundation for patient care information This
system is expensive outdated and prone to risky or life-threatening medical errors As a
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
7
result of broken down healthcare practices and system malfunctioning over 98000
Americans die and more than one million patients experience injuries every year
According to the National Academies between 30 and 40 of the healthcare costs
which is more than half a trillion dollars annually is used up on overuse underused
mishandling duplication system failures and redundant repetition poor
communication and inefficient healthcare practices
Information technology proposes vast potential benefits to enhance the functioning
and efficiency of US healthcare A completely realized national interoperable
healthcare IT (HIT) system could decrease errors improve communication assist in
eliminating redundancy and supply many other benefits that would guard the patients
and save up to tens of billions of dollars per year The fundamental challenge to
achieving such a system is interoperabilitymdashthe capability of data systems medical
devices and software from different vendors based on various array of platforms to
share patient electronic healthcare records (EHRs) electronic physician orders for lab
tests and drug prescriptions electronic referrals to specialists electronic access to
information about present suggested treatments and research findings and other
information
An important characteristic of a practical HIT system is that it protects the privacy and
confidentiality of patientsrsquo medical information It must also have strong data safety
provisions so that medical information cannot be altered or destroyed by illegal
entities HIT standards must include privacy and security in the original standards
design in order to make sure that these features will be an essential constituent of a
national HIT system
153 Hospital Information System
Various Hospital Information System (HIS) are being developed with the objective of
organizing the treatment process of a patient and allowing doctors and other staff to
perform to their maximum in an organized and efficient manner
It ensures benefits through technological advancement and is a guaranteed return for
investment It is operated in such a way that it is beneficial to both the recipients and
providers of healthcare because it is modeled on a unique combination of a patient
centric and medical staff centric paradigm
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
8
HIS uses a network of computers to gather process and retrieve patient care and
administrative information for easy availability to the users It helps the hospital
authorities by acting as decision support system for developing comprehensive health
care policies It incorporates an integrated computerized clinical information system for
improved hospital administration and patient health care It also helps to provide
updated electronic medical record of the patient These serves as data for research
undertaken by hospital authorities
HIS software is built around a highly optimized core library Application modules are
layered around this core and can be suitably customized for any user specific
requirements
Advantages of maintaining electronic records are
bull Reliable information storage querying and retrieval
bull Easy access to query data as the classification is based on many factors such as
age gender etc
bull Instant information access
bull Efficient and accurate administration of all hospital activities including finance
diet etc
bull Improved monitoring
Example of an effective HIS can be C-DACrsquos Sushrut A hospitalsrsquos administration can be
best explained through this example
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
9
Direct Sourcewwwcdacin
The various modules maintenance and functionality using this HIS can be explained as
1) Out-Patient Management
The out-patient module deals with recording the basic medical treatment details
required for the patient It consists of the following parts
a) Bay Management
This module depends on the registration module for the patients demographic
data
o Paging and Checking of patients in the bay
o Appointment scheduling of patients (normal and investigations)
o Printing of investigation requisition forms
b) Patient Visit Creation and maintenance
o Creation of sessions and recording of complaints and history
o Creation of visit and recording of clinical summary provisional
diagnosis drugs diets and Problem Oriented Medical Records
o Raising Investigation requisition
o Viewing of reports of tests for which results have been entered
o Printing of reports (visit record investigation reports etc)
o Allotment of beds for patients to be admitted
o Appointment Scheduling (normal and investigations)
o Closing of treatment session and recording of final diagnosis
o Making OPD summary and printing it
o Printing all pending investigation reports for a patient till date
o Facility to print duplicate investigation reports
o Printing a report on the total number of old patients handled during a
period
2) Investigation
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
10
For daily hospital activities various types of investigations are carried out Carrying out
number of investigation tests and making the results available promptly is very crucial
for assessing the patients medical status and deciding on the further course of action
The main functions of this module are generating investigation requisitions accepting
investigation requisitions collection of samples for investigations preparation of lab
reports sending samples to laboratories entry of test results and validation of results
Salient Features
bull Raising the Investigation Requisition
bull Sample Collection
bull Printing Packing List
bull AcceptingRejecting the samplesPatient in the Laboratory
bull Entering the details of the Film used in the Investigation
bull Entering the Investigation Results
bull Validation of the Investigation Results
bull Printing the Investigation Reports
bull Viewing of the Investigation results
bull Quality Control Check
bull Keeping track of films Slides issue and returns
bull Tracking of the status of a Test
bull Viewing and Printing of Work-list
3) Billing
The Billing module deals in collection of money for services availed by a patient The
module works in two ways
bull Money can be collected in cash for outpatient services availed
bull Advance can be collected when a patient is to be admitted In this case the
billing module maintains the status of each in-patients account The account is
finally settled when the patient is discharged
The module consists of the following sub-modules Cash Collection Account
Maintenance and Billing Reports
Salient features
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
11
a) Cash Collection
b) Account Maintenance
4) Appointments
This module deals in allotting appointments to patients for a visit to the hospital It
keeps track of available slots in various categories of appointments This module also
deals with cancellation of existing appointments
The module consists of
bull Appointment Scheduling
bull Appointment Cancellation
5) Operation theatre
The Operation Theatre module contains information about the availability of all the
theatres and EquipmentTools Scheduling of operations is the main function of this
module Various departments give the requisition for an operation theatre Various
Functions covered by this module are as follows
bull Operation Theatre Scheduling
bull Raising and validating an operation
bull Preparing an operation dossier
bull Entering Operation record
bull Entering Anesthesia record
6) Blood bank
The Blood Bank is one of the major components of a hospital concerned with various
related activities including donor registration physical examination blood grouping
blood infectious tests component separation blood requisition and cross match The
Blood Bank module provides ready information about blood reservestock daily cross-
matched details total daily blood requisitions and information regarding blood and
donor
7) In-Patient Management
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
2
Confidentiality statement
This document should not be carried outside the physical and virtual boundaries of TCS
and its client work locations The sharing of this document with any person other than
TCSer would tantamount to violation of confidentiality agreement signed by you while
joining TCS
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
3
Chapter 15 Role of IT in HealthCare
In this Chapter
The session discusses about the impact of IT in health care It talks about the nature and
scope of information power granted by IT It also deals with the influence of IT on the
design of healthcare systems Lastly it talks about bioinformatics
Learning Objectives
After reading this session you will know about
bull Impact of IT on healthcare
bull Impact of IT on the design of healthcare system
bull Nature and scope of information granted by IT
bull Role of IT in Life Sciences
Topics Covered
Chapter 15 Role of IT in HealthCare3
151 Introduction 4
152 Impact of IT on Healthcare 4
153 Hospital Information System 7
154 EHR (Electronic Healthcare Records) 14
155 Nature and Scope of Present Trends in IT and Health 18
1551 ITrsquos role in design of healthcare products and services 18
1552 ITrsquos impact on design of healthcare systems 20
1553 Nature and scope of information power granted by IT 20
1554 ITrsquos facilitating role in strengthening public-private partnerships 21
1555 IT-induced vulnerabilities and IT-aggravated risks 23
156 Information Technologyrsquos Role in Life Sciences Research amp Development 25
157 Bioinformatics Assists Drug Discovery and Development 27
158 The Indian Perspective 27
Summary 29
Deleted 15
Deleted 19
Deleted 21
Deleted 21
Deleted 22
Deleted 24
Deleted 26
Deleted 28
Deleted 29
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
4
151 Introduction
IT investment offers an environment for a new level of care to exist For example IT can
provide a prospect to evaluate trends that previously took much longer to identify
Enhanced information access can lead to rapid decision-making The confirmation of
better information leads to better care can be confirmed by the improvement in health
outcomes Better health outcomes include
bull diagnosing patients more accurately and quickly
bull act in accordance with patientsrsquo wishes and comforting the family
bull decreasing the number and severity of errors
bull supporting care delivery through improved access to information
Information technology (IT) has significantly reduced the costs improved the speed
and enhanced the efficiency of life sciences research and development (RampD) The RampD
in turn has established new challenges and opportunities for IT applications This cycle
has added to an entire new frontier for knowledge production For example the union
of IT and biological progresses made possible the mapping of the whole human
genome and genomes of many other organisms in just over a decade These
inventions along with the current efforts to establish gene and protein functions have
enhanced our capacity to know the root causes of human animal and plant diseases
and find new cures for the same In addition to this many future IT innovations will
likely be stimulated by the data and analysis demands of the life sciences
152 Impact of IT on Healthcare
The maximum advancements of IT will be felt on release of healthcare Some of the
futuristic happenings would include
Right now there is a clear cut difference between healthcare product manufacturers
and marketers and the healthcare delivery systems Pharmaceutical corporations
belong to the previous group and hospitalsclinics are major parts of the healthcare
delivery systems in society IT will associate the two as one leading to blurring of the
boundaries Thus we would have a future situation where Pfizer would be concerned in
storing profiles of patients in a locked web site in an electronic format accessible via a
password through internet and WAP-mobile services Thus Pfizer would help identify
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
5
cases of hyperlipidemia store e-records and provide access to these to authorized
employees
The second impact of IT would be a new type of experts or companies ndash the electronic
healthcare information providers or healthcare counsel providers These healthcare and
IT knowledgeable people would help incorporate the vast database of health disease
and treatment related information including prevention and would assist therapy
givers provide the best integrated therapy for an individualrsquos sickness condition
The third impact of IT would be in the form of Pharma companies or connected
companies generating and sustaining electronic records of genetic profiles of people
and helping therapy givers give the best treatment based on the hereditary tendencies
of the patients
The fourth impact of IT would be societal media assisted word-of-mouth propagation of
healthcare information tips and knowledge These are very dominant influencers
Information technology presents huge potential benefits to US healthcare As per the
Institute of Medicine as many as 98000 people pass away in hospitals every year from
medical errors such as wrong medications and improper identification of diseases
many of which are preventable A study conducted by the Healthcare Information
Management Systems Society found out that approximately 49 of clinical diagnostic
testing is carried out since prior test results are not available when required
Applications of IT to healthcare such as electronic healthcare records (EHRs)
computerized ordering of prescriptions and tests and updated medical information for
clinical decision support can save thousands of lives and billions of dollars by
decreasing medical faults and miscommunication
The entry of IT into the healthcare has been slow and disorganized Only 12 of
practices with smaller number of physicians have adopted EHRs The healthcare
industry expends only 2 of revenues on information technology which is much lower
than the 10 average of other information-intensive industries
The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly accepted
technical standards In spite of the efforts at the Department of Health and Human
Services (HHS) since 2004 such standards have yet to be completely developed and
extensively propagated Furthermore there is also a need of conformance testing to
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
6
make sure that product and systems meet the terms of the set HIT interoperability
standards Without these standards and conformance tests healthcare providers are
unwilling to spend in HIT systems as there is no guarantee that they will be able to
correspond with other systems
The federal governmentrsquos lead organization for the progress and spread of technical
standards the National Institute of Standards and Technology (NIST) has been
concerned with HIT standards development work since 2005 With its extensive
expertise with issues of system interoperability data security and privacy and
consensus standards development NIST is well placed to make a larger contribution to
HIT standards development work and speed the use of a national secure and
interoperable HIT system
On May 21 2007 Chairman Bart Gordon introduced HR 2406 a bill to sanction NIST to
boost its efforts in support of the incorporation of the US healthcare information
project The bill
bull Directs NIST to set up an proposal for progressing HIT integration and permits it
to support healthcare representatives and organizations and federal agencies in
developing technical roadmaps for HIT standards
bull Requires NIST to build up or take up existing technology-neutral guidelines and
standards to facilitate federal agencies to efficiently choose and exercise HIT
systems that are safe interoperable and guarantee patient privacy
bull Requires the Department of Commerce to start a Senior Interagency Council on
Federal Healthcare Information Technology Infrastructure to synchronize the
development and deployment of federal HIT systems the related technology
transfer and federal work with private HIT standards development
organizations
bull Requires NIST to institute a university funding program for multidisciplinary
research in HIT-related fields and
bull Directs the National High-Performance Computing Program to organize federal
HIT RampD programs
Though the United States is the most technologically advanced nation in the world the
US healthcare system persists to depend on pen and paper for the bulk of its
information requirements From patient medical histories to prescriptions to hospital
charts handwritten notations are the foundation for patient care information This
system is expensive outdated and prone to risky or life-threatening medical errors As a
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
7
result of broken down healthcare practices and system malfunctioning over 98000
Americans die and more than one million patients experience injuries every year
According to the National Academies between 30 and 40 of the healthcare costs
which is more than half a trillion dollars annually is used up on overuse underused
mishandling duplication system failures and redundant repetition poor
communication and inefficient healthcare practices
Information technology proposes vast potential benefits to enhance the functioning
and efficiency of US healthcare A completely realized national interoperable
healthcare IT (HIT) system could decrease errors improve communication assist in
eliminating redundancy and supply many other benefits that would guard the patients
and save up to tens of billions of dollars per year The fundamental challenge to
achieving such a system is interoperabilitymdashthe capability of data systems medical
devices and software from different vendors based on various array of platforms to
share patient electronic healthcare records (EHRs) electronic physician orders for lab
tests and drug prescriptions electronic referrals to specialists electronic access to
information about present suggested treatments and research findings and other
information
An important characteristic of a practical HIT system is that it protects the privacy and
confidentiality of patientsrsquo medical information It must also have strong data safety
provisions so that medical information cannot be altered or destroyed by illegal
entities HIT standards must include privacy and security in the original standards
design in order to make sure that these features will be an essential constituent of a
national HIT system
153 Hospital Information System
Various Hospital Information System (HIS) are being developed with the objective of
organizing the treatment process of a patient and allowing doctors and other staff to
perform to their maximum in an organized and efficient manner
It ensures benefits through technological advancement and is a guaranteed return for
investment It is operated in such a way that it is beneficial to both the recipients and
providers of healthcare because it is modeled on a unique combination of a patient
centric and medical staff centric paradigm
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
8
HIS uses a network of computers to gather process and retrieve patient care and
administrative information for easy availability to the users It helps the hospital
authorities by acting as decision support system for developing comprehensive health
care policies It incorporates an integrated computerized clinical information system for
improved hospital administration and patient health care It also helps to provide
updated electronic medical record of the patient These serves as data for research
undertaken by hospital authorities
HIS software is built around a highly optimized core library Application modules are
layered around this core and can be suitably customized for any user specific
requirements
Advantages of maintaining electronic records are
bull Reliable information storage querying and retrieval
bull Easy access to query data as the classification is based on many factors such as
age gender etc
bull Instant information access
bull Efficient and accurate administration of all hospital activities including finance
diet etc
bull Improved monitoring
Example of an effective HIS can be C-DACrsquos Sushrut A hospitalsrsquos administration can be
best explained through this example
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
9
Direct Sourcewwwcdacin
The various modules maintenance and functionality using this HIS can be explained as
1) Out-Patient Management
The out-patient module deals with recording the basic medical treatment details
required for the patient It consists of the following parts
a) Bay Management
This module depends on the registration module for the patients demographic
data
o Paging and Checking of patients in the bay
o Appointment scheduling of patients (normal and investigations)
o Printing of investigation requisition forms
b) Patient Visit Creation and maintenance
o Creation of sessions and recording of complaints and history
o Creation of visit and recording of clinical summary provisional
diagnosis drugs diets and Problem Oriented Medical Records
o Raising Investigation requisition
o Viewing of reports of tests for which results have been entered
o Printing of reports (visit record investigation reports etc)
o Allotment of beds for patients to be admitted
o Appointment Scheduling (normal and investigations)
o Closing of treatment session and recording of final diagnosis
o Making OPD summary and printing it
o Printing all pending investigation reports for a patient till date
o Facility to print duplicate investigation reports
o Printing a report on the total number of old patients handled during a
period
2) Investigation
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
10
For daily hospital activities various types of investigations are carried out Carrying out
number of investigation tests and making the results available promptly is very crucial
for assessing the patients medical status and deciding on the further course of action
The main functions of this module are generating investigation requisitions accepting
investigation requisitions collection of samples for investigations preparation of lab
reports sending samples to laboratories entry of test results and validation of results
Salient Features
bull Raising the Investigation Requisition
bull Sample Collection
bull Printing Packing List
bull AcceptingRejecting the samplesPatient in the Laboratory
bull Entering the details of the Film used in the Investigation
bull Entering the Investigation Results
bull Validation of the Investigation Results
bull Printing the Investigation Reports
bull Viewing of the Investigation results
bull Quality Control Check
bull Keeping track of films Slides issue and returns
bull Tracking of the status of a Test
bull Viewing and Printing of Work-list
3) Billing
The Billing module deals in collection of money for services availed by a patient The
module works in two ways
bull Money can be collected in cash for outpatient services availed
bull Advance can be collected when a patient is to be admitted In this case the
billing module maintains the status of each in-patients account The account is
finally settled when the patient is discharged
The module consists of the following sub-modules Cash Collection Account
Maintenance and Billing Reports
Salient features
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
11
a) Cash Collection
b) Account Maintenance
4) Appointments
This module deals in allotting appointments to patients for a visit to the hospital It
keeps track of available slots in various categories of appointments This module also
deals with cancellation of existing appointments
The module consists of
bull Appointment Scheduling
bull Appointment Cancellation
5) Operation theatre
The Operation Theatre module contains information about the availability of all the
theatres and EquipmentTools Scheduling of operations is the main function of this
module Various departments give the requisition for an operation theatre Various
Functions covered by this module are as follows
bull Operation Theatre Scheduling
bull Raising and validating an operation
bull Preparing an operation dossier
bull Entering Operation record
bull Entering Anesthesia record
6) Blood bank
The Blood Bank is one of the major components of a hospital concerned with various
related activities including donor registration physical examination blood grouping
blood infectious tests component separation blood requisition and cross match The
Blood Bank module provides ready information about blood reservestock daily cross-
matched details total daily blood requisitions and information regarding blood and
donor
7) In-Patient Management
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
3
Chapter 15 Role of IT in HealthCare
In this Chapter
The session discusses about the impact of IT in health care It talks about the nature and
scope of information power granted by IT It also deals with the influence of IT on the
design of healthcare systems Lastly it talks about bioinformatics
Learning Objectives
After reading this session you will know about
bull Impact of IT on healthcare
bull Impact of IT on the design of healthcare system
bull Nature and scope of information granted by IT
bull Role of IT in Life Sciences
Topics Covered
Chapter 15 Role of IT in HealthCare3
151 Introduction 4
152 Impact of IT on Healthcare 4
153 Hospital Information System 7
154 EHR (Electronic Healthcare Records) 14
155 Nature and Scope of Present Trends in IT and Health 18
1551 ITrsquos role in design of healthcare products and services 18
1552 ITrsquos impact on design of healthcare systems 20
1553 Nature and scope of information power granted by IT 20
1554 ITrsquos facilitating role in strengthening public-private partnerships 21
1555 IT-induced vulnerabilities and IT-aggravated risks 23
156 Information Technologyrsquos Role in Life Sciences Research amp Development 25
157 Bioinformatics Assists Drug Discovery and Development 27
158 The Indian Perspective 27
Summary 29
Deleted 15
Deleted 19
Deleted 21
Deleted 21
Deleted 22
Deleted 24
Deleted 26
Deleted 28
Deleted 29
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
4
151 Introduction
IT investment offers an environment for a new level of care to exist For example IT can
provide a prospect to evaluate trends that previously took much longer to identify
Enhanced information access can lead to rapid decision-making The confirmation of
better information leads to better care can be confirmed by the improvement in health
outcomes Better health outcomes include
bull diagnosing patients more accurately and quickly
bull act in accordance with patientsrsquo wishes and comforting the family
bull decreasing the number and severity of errors
bull supporting care delivery through improved access to information
Information technology (IT) has significantly reduced the costs improved the speed
and enhanced the efficiency of life sciences research and development (RampD) The RampD
in turn has established new challenges and opportunities for IT applications This cycle
has added to an entire new frontier for knowledge production For example the union
of IT and biological progresses made possible the mapping of the whole human
genome and genomes of many other organisms in just over a decade These
inventions along with the current efforts to establish gene and protein functions have
enhanced our capacity to know the root causes of human animal and plant diseases
and find new cures for the same In addition to this many future IT innovations will
likely be stimulated by the data and analysis demands of the life sciences
152 Impact of IT on Healthcare
The maximum advancements of IT will be felt on release of healthcare Some of the
futuristic happenings would include
Right now there is a clear cut difference between healthcare product manufacturers
and marketers and the healthcare delivery systems Pharmaceutical corporations
belong to the previous group and hospitalsclinics are major parts of the healthcare
delivery systems in society IT will associate the two as one leading to blurring of the
boundaries Thus we would have a future situation where Pfizer would be concerned in
storing profiles of patients in a locked web site in an electronic format accessible via a
password through internet and WAP-mobile services Thus Pfizer would help identify
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
5
cases of hyperlipidemia store e-records and provide access to these to authorized
employees
The second impact of IT would be a new type of experts or companies ndash the electronic
healthcare information providers or healthcare counsel providers These healthcare and
IT knowledgeable people would help incorporate the vast database of health disease
and treatment related information including prevention and would assist therapy
givers provide the best integrated therapy for an individualrsquos sickness condition
The third impact of IT would be in the form of Pharma companies or connected
companies generating and sustaining electronic records of genetic profiles of people
and helping therapy givers give the best treatment based on the hereditary tendencies
of the patients
The fourth impact of IT would be societal media assisted word-of-mouth propagation of
healthcare information tips and knowledge These are very dominant influencers
Information technology presents huge potential benefits to US healthcare As per the
Institute of Medicine as many as 98000 people pass away in hospitals every year from
medical errors such as wrong medications and improper identification of diseases
many of which are preventable A study conducted by the Healthcare Information
Management Systems Society found out that approximately 49 of clinical diagnostic
testing is carried out since prior test results are not available when required
Applications of IT to healthcare such as electronic healthcare records (EHRs)
computerized ordering of prescriptions and tests and updated medical information for
clinical decision support can save thousands of lives and billions of dollars by
decreasing medical faults and miscommunication
The entry of IT into the healthcare has been slow and disorganized Only 12 of
practices with smaller number of physicians have adopted EHRs The healthcare
industry expends only 2 of revenues on information technology which is much lower
than the 10 average of other information-intensive industries
The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly accepted
technical standards In spite of the efforts at the Department of Health and Human
Services (HHS) since 2004 such standards have yet to be completely developed and
extensively propagated Furthermore there is also a need of conformance testing to
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
6
make sure that product and systems meet the terms of the set HIT interoperability
standards Without these standards and conformance tests healthcare providers are
unwilling to spend in HIT systems as there is no guarantee that they will be able to
correspond with other systems
The federal governmentrsquos lead organization for the progress and spread of technical
standards the National Institute of Standards and Technology (NIST) has been
concerned with HIT standards development work since 2005 With its extensive
expertise with issues of system interoperability data security and privacy and
consensus standards development NIST is well placed to make a larger contribution to
HIT standards development work and speed the use of a national secure and
interoperable HIT system
On May 21 2007 Chairman Bart Gordon introduced HR 2406 a bill to sanction NIST to
boost its efforts in support of the incorporation of the US healthcare information
project The bill
bull Directs NIST to set up an proposal for progressing HIT integration and permits it
to support healthcare representatives and organizations and federal agencies in
developing technical roadmaps for HIT standards
bull Requires NIST to build up or take up existing technology-neutral guidelines and
standards to facilitate federal agencies to efficiently choose and exercise HIT
systems that are safe interoperable and guarantee patient privacy
bull Requires the Department of Commerce to start a Senior Interagency Council on
Federal Healthcare Information Technology Infrastructure to synchronize the
development and deployment of federal HIT systems the related technology
transfer and federal work with private HIT standards development
organizations
bull Requires NIST to institute a university funding program for multidisciplinary
research in HIT-related fields and
bull Directs the National High-Performance Computing Program to organize federal
HIT RampD programs
Though the United States is the most technologically advanced nation in the world the
US healthcare system persists to depend on pen and paper for the bulk of its
information requirements From patient medical histories to prescriptions to hospital
charts handwritten notations are the foundation for patient care information This
system is expensive outdated and prone to risky or life-threatening medical errors As a
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
7
result of broken down healthcare practices and system malfunctioning over 98000
Americans die and more than one million patients experience injuries every year
According to the National Academies between 30 and 40 of the healthcare costs
which is more than half a trillion dollars annually is used up on overuse underused
mishandling duplication system failures and redundant repetition poor
communication and inefficient healthcare practices
Information technology proposes vast potential benefits to enhance the functioning
and efficiency of US healthcare A completely realized national interoperable
healthcare IT (HIT) system could decrease errors improve communication assist in
eliminating redundancy and supply many other benefits that would guard the patients
and save up to tens of billions of dollars per year The fundamental challenge to
achieving such a system is interoperabilitymdashthe capability of data systems medical
devices and software from different vendors based on various array of platforms to
share patient electronic healthcare records (EHRs) electronic physician orders for lab
tests and drug prescriptions electronic referrals to specialists electronic access to
information about present suggested treatments and research findings and other
information
An important characteristic of a practical HIT system is that it protects the privacy and
confidentiality of patientsrsquo medical information It must also have strong data safety
provisions so that medical information cannot be altered or destroyed by illegal
entities HIT standards must include privacy and security in the original standards
design in order to make sure that these features will be an essential constituent of a
national HIT system
153 Hospital Information System
Various Hospital Information System (HIS) are being developed with the objective of
organizing the treatment process of a patient and allowing doctors and other staff to
perform to their maximum in an organized and efficient manner
It ensures benefits through technological advancement and is a guaranteed return for
investment It is operated in such a way that it is beneficial to both the recipients and
providers of healthcare because it is modeled on a unique combination of a patient
centric and medical staff centric paradigm
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
8
HIS uses a network of computers to gather process and retrieve patient care and
administrative information for easy availability to the users It helps the hospital
authorities by acting as decision support system for developing comprehensive health
care policies It incorporates an integrated computerized clinical information system for
improved hospital administration and patient health care It also helps to provide
updated electronic medical record of the patient These serves as data for research
undertaken by hospital authorities
HIS software is built around a highly optimized core library Application modules are
layered around this core and can be suitably customized for any user specific
requirements
Advantages of maintaining electronic records are
bull Reliable information storage querying and retrieval
bull Easy access to query data as the classification is based on many factors such as
age gender etc
bull Instant information access
bull Efficient and accurate administration of all hospital activities including finance
diet etc
bull Improved monitoring
Example of an effective HIS can be C-DACrsquos Sushrut A hospitalsrsquos administration can be
best explained through this example
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
9
Direct Sourcewwwcdacin
The various modules maintenance and functionality using this HIS can be explained as
1) Out-Patient Management
The out-patient module deals with recording the basic medical treatment details
required for the patient It consists of the following parts
a) Bay Management
This module depends on the registration module for the patients demographic
data
o Paging and Checking of patients in the bay
o Appointment scheduling of patients (normal and investigations)
o Printing of investigation requisition forms
b) Patient Visit Creation and maintenance
o Creation of sessions and recording of complaints and history
o Creation of visit and recording of clinical summary provisional
diagnosis drugs diets and Problem Oriented Medical Records
o Raising Investigation requisition
o Viewing of reports of tests for which results have been entered
o Printing of reports (visit record investigation reports etc)
o Allotment of beds for patients to be admitted
o Appointment Scheduling (normal and investigations)
o Closing of treatment session and recording of final diagnosis
o Making OPD summary and printing it
o Printing all pending investigation reports for a patient till date
o Facility to print duplicate investigation reports
o Printing a report on the total number of old patients handled during a
period
2) Investigation
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
10
For daily hospital activities various types of investigations are carried out Carrying out
number of investigation tests and making the results available promptly is very crucial
for assessing the patients medical status and deciding on the further course of action
The main functions of this module are generating investigation requisitions accepting
investigation requisitions collection of samples for investigations preparation of lab
reports sending samples to laboratories entry of test results and validation of results
Salient Features
bull Raising the Investigation Requisition
bull Sample Collection
bull Printing Packing List
bull AcceptingRejecting the samplesPatient in the Laboratory
bull Entering the details of the Film used in the Investigation
bull Entering the Investigation Results
bull Validation of the Investigation Results
bull Printing the Investigation Reports
bull Viewing of the Investigation results
bull Quality Control Check
bull Keeping track of films Slides issue and returns
bull Tracking of the status of a Test
bull Viewing and Printing of Work-list
3) Billing
The Billing module deals in collection of money for services availed by a patient The
module works in two ways
bull Money can be collected in cash for outpatient services availed
bull Advance can be collected when a patient is to be admitted In this case the
billing module maintains the status of each in-patients account The account is
finally settled when the patient is discharged
The module consists of the following sub-modules Cash Collection Account
Maintenance and Billing Reports
Salient features
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
11
a) Cash Collection
b) Account Maintenance
4) Appointments
This module deals in allotting appointments to patients for a visit to the hospital It
keeps track of available slots in various categories of appointments This module also
deals with cancellation of existing appointments
The module consists of
bull Appointment Scheduling
bull Appointment Cancellation
5) Operation theatre
The Operation Theatre module contains information about the availability of all the
theatres and EquipmentTools Scheduling of operations is the main function of this
module Various departments give the requisition for an operation theatre Various
Functions covered by this module are as follows
bull Operation Theatre Scheduling
bull Raising and validating an operation
bull Preparing an operation dossier
bull Entering Operation record
bull Entering Anesthesia record
6) Blood bank
The Blood Bank is one of the major components of a hospital concerned with various
related activities including donor registration physical examination blood grouping
blood infectious tests component separation blood requisition and cross match The
Blood Bank module provides ready information about blood reservestock daily cross-
matched details total daily blood requisitions and information regarding blood and
donor
7) In-Patient Management
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
4
151 Introduction
IT investment offers an environment for a new level of care to exist For example IT can
provide a prospect to evaluate trends that previously took much longer to identify
Enhanced information access can lead to rapid decision-making The confirmation of
better information leads to better care can be confirmed by the improvement in health
outcomes Better health outcomes include
bull diagnosing patients more accurately and quickly
bull act in accordance with patientsrsquo wishes and comforting the family
bull decreasing the number and severity of errors
bull supporting care delivery through improved access to information
Information technology (IT) has significantly reduced the costs improved the speed
and enhanced the efficiency of life sciences research and development (RampD) The RampD
in turn has established new challenges and opportunities for IT applications This cycle
has added to an entire new frontier for knowledge production For example the union
of IT and biological progresses made possible the mapping of the whole human
genome and genomes of many other organisms in just over a decade These
inventions along with the current efforts to establish gene and protein functions have
enhanced our capacity to know the root causes of human animal and plant diseases
and find new cures for the same In addition to this many future IT innovations will
likely be stimulated by the data and analysis demands of the life sciences
152 Impact of IT on Healthcare
The maximum advancements of IT will be felt on release of healthcare Some of the
futuristic happenings would include
Right now there is a clear cut difference between healthcare product manufacturers
and marketers and the healthcare delivery systems Pharmaceutical corporations
belong to the previous group and hospitalsclinics are major parts of the healthcare
delivery systems in society IT will associate the two as one leading to blurring of the
boundaries Thus we would have a future situation where Pfizer would be concerned in
storing profiles of patients in a locked web site in an electronic format accessible via a
password through internet and WAP-mobile services Thus Pfizer would help identify
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
5
cases of hyperlipidemia store e-records and provide access to these to authorized
employees
The second impact of IT would be a new type of experts or companies ndash the electronic
healthcare information providers or healthcare counsel providers These healthcare and
IT knowledgeable people would help incorporate the vast database of health disease
and treatment related information including prevention and would assist therapy
givers provide the best integrated therapy for an individualrsquos sickness condition
The third impact of IT would be in the form of Pharma companies or connected
companies generating and sustaining electronic records of genetic profiles of people
and helping therapy givers give the best treatment based on the hereditary tendencies
of the patients
The fourth impact of IT would be societal media assisted word-of-mouth propagation of
healthcare information tips and knowledge These are very dominant influencers
Information technology presents huge potential benefits to US healthcare As per the
Institute of Medicine as many as 98000 people pass away in hospitals every year from
medical errors such as wrong medications and improper identification of diseases
many of which are preventable A study conducted by the Healthcare Information
Management Systems Society found out that approximately 49 of clinical diagnostic
testing is carried out since prior test results are not available when required
Applications of IT to healthcare such as electronic healthcare records (EHRs)
computerized ordering of prescriptions and tests and updated medical information for
clinical decision support can save thousands of lives and billions of dollars by
decreasing medical faults and miscommunication
The entry of IT into the healthcare has been slow and disorganized Only 12 of
practices with smaller number of physicians have adopted EHRs The healthcare
industry expends only 2 of revenues on information technology which is much lower
than the 10 average of other information-intensive industries
The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly accepted
technical standards In spite of the efforts at the Department of Health and Human
Services (HHS) since 2004 such standards have yet to be completely developed and
extensively propagated Furthermore there is also a need of conformance testing to
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
6
make sure that product and systems meet the terms of the set HIT interoperability
standards Without these standards and conformance tests healthcare providers are
unwilling to spend in HIT systems as there is no guarantee that they will be able to
correspond with other systems
The federal governmentrsquos lead organization for the progress and spread of technical
standards the National Institute of Standards and Technology (NIST) has been
concerned with HIT standards development work since 2005 With its extensive
expertise with issues of system interoperability data security and privacy and
consensus standards development NIST is well placed to make a larger contribution to
HIT standards development work and speed the use of a national secure and
interoperable HIT system
On May 21 2007 Chairman Bart Gordon introduced HR 2406 a bill to sanction NIST to
boost its efforts in support of the incorporation of the US healthcare information
project The bill
bull Directs NIST to set up an proposal for progressing HIT integration and permits it
to support healthcare representatives and organizations and federal agencies in
developing technical roadmaps for HIT standards
bull Requires NIST to build up or take up existing technology-neutral guidelines and
standards to facilitate federal agencies to efficiently choose and exercise HIT
systems that are safe interoperable and guarantee patient privacy
bull Requires the Department of Commerce to start a Senior Interagency Council on
Federal Healthcare Information Technology Infrastructure to synchronize the
development and deployment of federal HIT systems the related technology
transfer and federal work with private HIT standards development
organizations
bull Requires NIST to institute a university funding program for multidisciplinary
research in HIT-related fields and
bull Directs the National High-Performance Computing Program to organize federal
HIT RampD programs
Though the United States is the most technologically advanced nation in the world the
US healthcare system persists to depend on pen and paper for the bulk of its
information requirements From patient medical histories to prescriptions to hospital
charts handwritten notations are the foundation for patient care information This
system is expensive outdated and prone to risky or life-threatening medical errors As a
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
7
result of broken down healthcare practices and system malfunctioning over 98000
Americans die and more than one million patients experience injuries every year
According to the National Academies between 30 and 40 of the healthcare costs
which is more than half a trillion dollars annually is used up on overuse underused
mishandling duplication system failures and redundant repetition poor
communication and inefficient healthcare practices
Information technology proposes vast potential benefits to enhance the functioning
and efficiency of US healthcare A completely realized national interoperable
healthcare IT (HIT) system could decrease errors improve communication assist in
eliminating redundancy and supply many other benefits that would guard the patients
and save up to tens of billions of dollars per year The fundamental challenge to
achieving such a system is interoperabilitymdashthe capability of data systems medical
devices and software from different vendors based on various array of platforms to
share patient electronic healthcare records (EHRs) electronic physician orders for lab
tests and drug prescriptions electronic referrals to specialists electronic access to
information about present suggested treatments and research findings and other
information
An important characteristic of a practical HIT system is that it protects the privacy and
confidentiality of patientsrsquo medical information It must also have strong data safety
provisions so that medical information cannot be altered or destroyed by illegal
entities HIT standards must include privacy and security in the original standards
design in order to make sure that these features will be an essential constituent of a
national HIT system
153 Hospital Information System
Various Hospital Information System (HIS) are being developed with the objective of
organizing the treatment process of a patient and allowing doctors and other staff to
perform to their maximum in an organized and efficient manner
It ensures benefits through technological advancement and is a guaranteed return for
investment It is operated in such a way that it is beneficial to both the recipients and
providers of healthcare because it is modeled on a unique combination of a patient
centric and medical staff centric paradigm
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
8
HIS uses a network of computers to gather process and retrieve patient care and
administrative information for easy availability to the users It helps the hospital
authorities by acting as decision support system for developing comprehensive health
care policies It incorporates an integrated computerized clinical information system for
improved hospital administration and patient health care It also helps to provide
updated electronic medical record of the patient These serves as data for research
undertaken by hospital authorities
HIS software is built around a highly optimized core library Application modules are
layered around this core and can be suitably customized for any user specific
requirements
Advantages of maintaining electronic records are
bull Reliable information storage querying and retrieval
bull Easy access to query data as the classification is based on many factors such as
age gender etc
bull Instant information access
bull Efficient and accurate administration of all hospital activities including finance
diet etc
bull Improved monitoring
Example of an effective HIS can be C-DACrsquos Sushrut A hospitalsrsquos administration can be
best explained through this example
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
9
Direct Sourcewwwcdacin
The various modules maintenance and functionality using this HIS can be explained as
1) Out-Patient Management
The out-patient module deals with recording the basic medical treatment details
required for the patient It consists of the following parts
a) Bay Management
This module depends on the registration module for the patients demographic
data
o Paging and Checking of patients in the bay
o Appointment scheduling of patients (normal and investigations)
o Printing of investigation requisition forms
b) Patient Visit Creation and maintenance
o Creation of sessions and recording of complaints and history
o Creation of visit and recording of clinical summary provisional
diagnosis drugs diets and Problem Oriented Medical Records
o Raising Investigation requisition
o Viewing of reports of tests for which results have been entered
o Printing of reports (visit record investigation reports etc)
o Allotment of beds for patients to be admitted
o Appointment Scheduling (normal and investigations)
o Closing of treatment session and recording of final diagnosis
o Making OPD summary and printing it
o Printing all pending investigation reports for a patient till date
o Facility to print duplicate investigation reports
o Printing a report on the total number of old patients handled during a
period
2) Investigation
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
10
For daily hospital activities various types of investigations are carried out Carrying out
number of investigation tests and making the results available promptly is very crucial
for assessing the patients medical status and deciding on the further course of action
The main functions of this module are generating investigation requisitions accepting
investigation requisitions collection of samples for investigations preparation of lab
reports sending samples to laboratories entry of test results and validation of results
Salient Features
bull Raising the Investigation Requisition
bull Sample Collection
bull Printing Packing List
bull AcceptingRejecting the samplesPatient in the Laboratory
bull Entering the details of the Film used in the Investigation
bull Entering the Investigation Results
bull Validation of the Investigation Results
bull Printing the Investigation Reports
bull Viewing of the Investigation results
bull Quality Control Check
bull Keeping track of films Slides issue and returns
bull Tracking of the status of a Test
bull Viewing and Printing of Work-list
3) Billing
The Billing module deals in collection of money for services availed by a patient The
module works in two ways
bull Money can be collected in cash for outpatient services availed
bull Advance can be collected when a patient is to be admitted In this case the
billing module maintains the status of each in-patients account The account is
finally settled when the patient is discharged
The module consists of the following sub-modules Cash Collection Account
Maintenance and Billing Reports
Salient features
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
11
a) Cash Collection
b) Account Maintenance
4) Appointments
This module deals in allotting appointments to patients for a visit to the hospital It
keeps track of available slots in various categories of appointments This module also
deals with cancellation of existing appointments
The module consists of
bull Appointment Scheduling
bull Appointment Cancellation
5) Operation theatre
The Operation Theatre module contains information about the availability of all the
theatres and EquipmentTools Scheduling of operations is the main function of this
module Various departments give the requisition for an operation theatre Various
Functions covered by this module are as follows
bull Operation Theatre Scheduling
bull Raising and validating an operation
bull Preparing an operation dossier
bull Entering Operation record
bull Entering Anesthesia record
6) Blood bank
The Blood Bank is one of the major components of a hospital concerned with various
related activities including donor registration physical examination blood grouping
blood infectious tests component separation blood requisition and cross match The
Blood Bank module provides ready information about blood reservestock daily cross-
matched details total daily blood requisitions and information regarding blood and
donor
7) In-Patient Management
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
5
cases of hyperlipidemia store e-records and provide access to these to authorized
employees
The second impact of IT would be a new type of experts or companies ndash the electronic
healthcare information providers or healthcare counsel providers These healthcare and
IT knowledgeable people would help incorporate the vast database of health disease
and treatment related information including prevention and would assist therapy
givers provide the best integrated therapy for an individualrsquos sickness condition
The third impact of IT would be in the form of Pharma companies or connected
companies generating and sustaining electronic records of genetic profiles of people
and helping therapy givers give the best treatment based on the hereditary tendencies
of the patients
The fourth impact of IT would be societal media assisted word-of-mouth propagation of
healthcare information tips and knowledge These are very dominant influencers
Information technology presents huge potential benefits to US healthcare As per the
Institute of Medicine as many as 98000 people pass away in hospitals every year from
medical errors such as wrong medications and improper identification of diseases
many of which are preventable A study conducted by the Healthcare Information
Management Systems Society found out that approximately 49 of clinical diagnostic
testing is carried out since prior test results are not available when required
Applications of IT to healthcare such as electronic healthcare records (EHRs)
computerized ordering of prescriptions and tests and updated medical information for
clinical decision support can save thousands of lives and billions of dollars by
decreasing medical faults and miscommunication
The entry of IT into the healthcare has been slow and disorganized Only 12 of
practices with smaller number of physicians have adopted EHRs The healthcare
industry expends only 2 of revenues on information technology which is much lower
than the 10 average of other information-intensive industries
The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly accepted
technical standards In spite of the efforts at the Department of Health and Human
Services (HHS) since 2004 such standards have yet to be completely developed and
extensively propagated Furthermore there is also a need of conformance testing to
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
6
make sure that product and systems meet the terms of the set HIT interoperability
standards Without these standards and conformance tests healthcare providers are
unwilling to spend in HIT systems as there is no guarantee that they will be able to
correspond with other systems
The federal governmentrsquos lead organization for the progress and spread of technical
standards the National Institute of Standards and Technology (NIST) has been
concerned with HIT standards development work since 2005 With its extensive
expertise with issues of system interoperability data security and privacy and
consensus standards development NIST is well placed to make a larger contribution to
HIT standards development work and speed the use of a national secure and
interoperable HIT system
On May 21 2007 Chairman Bart Gordon introduced HR 2406 a bill to sanction NIST to
boost its efforts in support of the incorporation of the US healthcare information
project The bill
bull Directs NIST to set up an proposal for progressing HIT integration and permits it
to support healthcare representatives and organizations and federal agencies in
developing technical roadmaps for HIT standards
bull Requires NIST to build up or take up existing technology-neutral guidelines and
standards to facilitate federal agencies to efficiently choose and exercise HIT
systems that are safe interoperable and guarantee patient privacy
bull Requires the Department of Commerce to start a Senior Interagency Council on
Federal Healthcare Information Technology Infrastructure to synchronize the
development and deployment of federal HIT systems the related technology
transfer and federal work with private HIT standards development
organizations
bull Requires NIST to institute a university funding program for multidisciplinary
research in HIT-related fields and
bull Directs the National High-Performance Computing Program to organize federal
HIT RampD programs
Though the United States is the most technologically advanced nation in the world the
US healthcare system persists to depend on pen and paper for the bulk of its
information requirements From patient medical histories to prescriptions to hospital
charts handwritten notations are the foundation for patient care information This
system is expensive outdated and prone to risky or life-threatening medical errors As a
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
7
result of broken down healthcare practices and system malfunctioning over 98000
Americans die and more than one million patients experience injuries every year
According to the National Academies between 30 and 40 of the healthcare costs
which is more than half a trillion dollars annually is used up on overuse underused
mishandling duplication system failures and redundant repetition poor
communication and inefficient healthcare practices
Information technology proposes vast potential benefits to enhance the functioning
and efficiency of US healthcare A completely realized national interoperable
healthcare IT (HIT) system could decrease errors improve communication assist in
eliminating redundancy and supply many other benefits that would guard the patients
and save up to tens of billions of dollars per year The fundamental challenge to
achieving such a system is interoperabilitymdashthe capability of data systems medical
devices and software from different vendors based on various array of platforms to
share patient electronic healthcare records (EHRs) electronic physician orders for lab
tests and drug prescriptions electronic referrals to specialists electronic access to
information about present suggested treatments and research findings and other
information
An important characteristic of a practical HIT system is that it protects the privacy and
confidentiality of patientsrsquo medical information It must also have strong data safety
provisions so that medical information cannot be altered or destroyed by illegal
entities HIT standards must include privacy and security in the original standards
design in order to make sure that these features will be an essential constituent of a
national HIT system
153 Hospital Information System
Various Hospital Information System (HIS) are being developed with the objective of
organizing the treatment process of a patient and allowing doctors and other staff to
perform to their maximum in an organized and efficient manner
It ensures benefits through technological advancement and is a guaranteed return for
investment It is operated in such a way that it is beneficial to both the recipients and
providers of healthcare because it is modeled on a unique combination of a patient
centric and medical staff centric paradigm
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
8
HIS uses a network of computers to gather process and retrieve patient care and
administrative information for easy availability to the users It helps the hospital
authorities by acting as decision support system for developing comprehensive health
care policies It incorporates an integrated computerized clinical information system for
improved hospital administration and patient health care It also helps to provide
updated electronic medical record of the patient These serves as data for research
undertaken by hospital authorities
HIS software is built around a highly optimized core library Application modules are
layered around this core and can be suitably customized for any user specific
requirements
Advantages of maintaining electronic records are
bull Reliable information storage querying and retrieval
bull Easy access to query data as the classification is based on many factors such as
age gender etc
bull Instant information access
bull Efficient and accurate administration of all hospital activities including finance
diet etc
bull Improved monitoring
Example of an effective HIS can be C-DACrsquos Sushrut A hospitalsrsquos administration can be
best explained through this example
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9
Direct Sourcewwwcdacin
The various modules maintenance and functionality using this HIS can be explained as
1) Out-Patient Management
The out-patient module deals with recording the basic medical treatment details
required for the patient It consists of the following parts
a) Bay Management
This module depends on the registration module for the patients demographic
data
o Paging and Checking of patients in the bay
o Appointment scheduling of patients (normal and investigations)
o Printing of investigation requisition forms
b) Patient Visit Creation and maintenance
o Creation of sessions and recording of complaints and history
o Creation of visit and recording of clinical summary provisional
diagnosis drugs diets and Problem Oriented Medical Records
o Raising Investigation requisition
o Viewing of reports of tests for which results have been entered
o Printing of reports (visit record investigation reports etc)
o Allotment of beds for patients to be admitted
o Appointment Scheduling (normal and investigations)
o Closing of treatment session and recording of final diagnosis
o Making OPD summary and printing it
o Printing all pending investigation reports for a patient till date
o Facility to print duplicate investigation reports
o Printing a report on the total number of old patients handled during a
period
2) Investigation
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10
For daily hospital activities various types of investigations are carried out Carrying out
number of investigation tests and making the results available promptly is very crucial
for assessing the patients medical status and deciding on the further course of action
The main functions of this module are generating investigation requisitions accepting
investigation requisitions collection of samples for investigations preparation of lab
reports sending samples to laboratories entry of test results and validation of results
Salient Features
bull Raising the Investigation Requisition
bull Sample Collection
bull Printing Packing List
bull AcceptingRejecting the samplesPatient in the Laboratory
bull Entering the details of the Film used in the Investigation
bull Entering the Investigation Results
bull Validation of the Investigation Results
bull Printing the Investigation Reports
bull Viewing of the Investigation results
bull Quality Control Check
bull Keeping track of films Slides issue and returns
bull Tracking of the status of a Test
bull Viewing and Printing of Work-list
3) Billing
The Billing module deals in collection of money for services availed by a patient The
module works in two ways
bull Money can be collected in cash for outpatient services availed
bull Advance can be collected when a patient is to be admitted In this case the
billing module maintains the status of each in-patients account The account is
finally settled when the patient is discharged
The module consists of the following sub-modules Cash Collection Account
Maintenance and Billing Reports
Salient features
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
11
a) Cash Collection
b) Account Maintenance
4) Appointments
This module deals in allotting appointments to patients for a visit to the hospital It
keeps track of available slots in various categories of appointments This module also
deals with cancellation of existing appointments
The module consists of
bull Appointment Scheduling
bull Appointment Cancellation
5) Operation theatre
The Operation Theatre module contains information about the availability of all the
theatres and EquipmentTools Scheduling of operations is the main function of this
module Various departments give the requisition for an operation theatre Various
Functions covered by this module are as follows
bull Operation Theatre Scheduling
bull Raising and validating an operation
bull Preparing an operation dossier
bull Entering Operation record
bull Entering Anesthesia record
6) Blood bank
The Blood Bank is one of the major components of a hospital concerned with various
related activities including donor registration physical examination blood grouping
blood infectious tests component separation blood requisition and cross match The
Blood Bank module provides ready information about blood reservestock daily cross-
matched details total daily blood requisitions and information regarding blood and
donor
7) In-Patient Management
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
6
make sure that product and systems meet the terms of the set HIT interoperability
standards Without these standards and conformance tests healthcare providers are
unwilling to spend in HIT systems as there is no guarantee that they will be able to
correspond with other systems
The federal governmentrsquos lead organization for the progress and spread of technical
standards the National Institute of Standards and Technology (NIST) has been
concerned with HIT standards development work since 2005 With its extensive
expertise with issues of system interoperability data security and privacy and
consensus standards development NIST is well placed to make a larger contribution to
HIT standards development work and speed the use of a national secure and
interoperable HIT system
On May 21 2007 Chairman Bart Gordon introduced HR 2406 a bill to sanction NIST to
boost its efforts in support of the incorporation of the US healthcare information
project The bill
bull Directs NIST to set up an proposal for progressing HIT integration and permits it
to support healthcare representatives and organizations and federal agencies in
developing technical roadmaps for HIT standards
bull Requires NIST to build up or take up existing technology-neutral guidelines and
standards to facilitate federal agencies to efficiently choose and exercise HIT
systems that are safe interoperable and guarantee patient privacy
bull Requires the Department of Commerce to start a Senior Interagency Council on
Federal Healthcare Information Technology Infrastructure to synchronize the
development and deployment of federal HIT systems the related technology
transfer and federal work with private HIT standards development
organizations
bull Requires NIST to institute a university funding program for multidisciplinary
research in HIT-related fields and
bull Directs the National High-Performance Computing Program to organize federal
HIT RampD programs
Though the United States is the most technologically advanced nation in the world the
US healthcare system persists to depend on pen and paper for the bulk of its
information requirements From patient medical histories to prescriptions to hospital
charts handwritten notations are the foundation for patient care information This
system is expensive outdated and prone to risky or life-threatening medical errors As a
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
7
result of broken down healthcare practices and system malfunctioning over 98000
Americans die and more than one million patients experience injuries every year
According to the National Academies between 30 and 40 of the healthcare costs
which is more than half a trillion dollars annually is used up on overuse underused
mishandling duplication system failures and redundant repetition poor
communication and inefficient healthcare practices
Information technology proposes vast potential benefits to enhance the functioning
and efficiency of US healthcare A completely realized national interoperable
healthcare IT (HIT) system could decrease errors improve communication assist in
eliminating redundancy and supply many other benefits that would guard the patients
and save up to tens of billions of dollars per year The fundamental challenge to
achieving such a system is interoperabilitymdashthe capability of data systems medical
devices and software from different vendors based on various array of platforms to
share patient electronic healthcare records (EHRs) electronic physician orders for lab
tests and drug prescriptions electronic referrals to specialists electronic access to
information about present suggested treatments and research findings and other
information
An important characteristic of a practical HIT system is that it protects the privacy and
confidentiality of patientsrsquo medical information It must also have strong data safety
provisions so that medical information cannot be altered or destroyed by illegal
entities HIT standards must include privacy and security in the original standards
design in order to make sure that these features will be an essential constituent of a
national HIT system
153 Hospital Information System
Various Hospital Information System (HIS) are being developed with the objective of
organizing the treatment process of a patient and allowing doctors and other staff to
perform to their maximum in an organized and efficient manner
It ensures benefits through technological advancement and is a guaranteed return for
investment It is operated in such a way that it is beneficial to both the recipients and
providers of healthcare because it is modeled on a unique combination of a patient
centric and medical staff centric paradigm
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
8
HIS uses a network of computers to gather process and retrieve patient care and
administrative information for easy availability to the users It helps the hospital
authorities by acting as decision support system for developing comprehensive health
care policies It incorporates an integrated computerized clinical information system for
improved hospital administration and patient health care It also helps to provide
updated electronic medical record of the patient These serves as data for research
undertaken by hospital authorities
HIS software is built around a highly optimized core library Application modules are
layered around this core and can be suitably customized for any user specific
requirements
Advantages of maintaining electronic records are
bull Reliable information storage querying and retrieval
bull Easy access to query data as the classification is based on many factors such as
age gender etc
bull Instant information access
bull Efficient and accurate administration of all hospital activities including finance
diet etc
bull Improved monitoring
Example of an effective HIS can be C-DACrsquos Sushrut A hospitalsrsquos administration can be
best explained through this example
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
9
Direct Sourcewwwcdacin
The various modules maintenance and functionality using this HIS can be explained as
1) Out-Patient Management
The out-patient module deals with recording the basic medical treatment details
required for the patient It consists of the following parts
a) Bay Management
This module depends on the registration module for the patients demographic
data
o Paging and Checking of patients in the bay
o Appointment scheduling of patients (normal and investigations)
o Printing of investigation requisition forms
b) Patient Visit Creation and maintenance
o Creation of sessions and recording of complaints and history
o Creation of visit and recording of clinical summary provisional
diagnosis drugs diets and Problem Oriented Medical Records
o Raising Investigation requisition
o Viewing of reports of tests for which results have been entered
o Printing of reports (visit record investigation reports etc)
o Allotment of beds for patients to be admitted
o Appointment Scheduling (normal and investigations)
o Closing of treatment session and recording of final diagnosis
o Making OPD summary and printing it
o Printing all pending investigation reports for a patient till date
o Facility to print duplicate investigation reports
o Printing a report on the total number of old patients handled during a
period
2) Investigation
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
10
For daily hospital activities various types of investigations are carried out Carrying out
number of investigation tests and making the results available promptly is very crucial
for assessing the patients medical status and deciding on the further course of action
The main functions of this module are generating investigation requisitions accepting
investigation requisitions collection of samples for investigations preparation of lab
reports sending samples to laboratories entry of test results and validation of results
Salient Features
bull Raising the Investigation Requisition
bull Sample Collection
bull Printing Packing List
bull AcceptingRejecting the samplesPatient in the Laboratory
bull Entering the details of the Film used in the Investigation
bull Entering the Investigation Results
bull Validation of the Investigation Results
bull Printing the Investigation Reports
bull Viewing of the Investigation results
bull Quality Control Check
bull Keeping track of films Slides issue and returns
bull Tracking of the status of a Test
bull Viewing and Printing of Work-list
3) Billing
The Billing module deals in collection of money for services availed by a patient The
module works in two ways
bull Money can be collected in cash for outpatient services availed
bull Advance can be collected when a patient is to be admitted In this case the
billing module maintains the status of each in-patients account The account is
finally settled when the patient is discharged
The module consists of the following sub-modules Cash Collection Account
Maintenance and Billing Reports
Salient features
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
11
a) Cash Collection
b) Account Maintenance
4) Appointments
This module deals in allotting appointments to patients for a visit to the hospital It
keeps track of available slots in various categories of appointments This module also
deals with cancellation of existing appointments
The module consists of
bull Appointment Scheduling
bull Appointment Cancellation
5) Operation theatre
The Operation Theatre module contains information about the availability of all the
theatres and EquipmentTools Scheduling of operations is the main function of this
module Various departments give the requisition for an operation theatre Various
Functions covered by this module are as follows
bull Operation Theatre Scheduling
bull Raising and validating an operation
bull Preparing an operation dossier
bull Entering Operation record
bull Entering Anesthesia record
6) Blood bank
The Blood Bank is one of the major components of a hospital concerned with various
related activities including donor registration physical examination blood grouping
blood infectious tests component separation blood requisition and cross match The
Blood Bank module provides ready information about blood reservestock daily cross-
matched details total daily blood requisitions and information regarding blood and
donor
7) In-Patient Management
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
7
result of broken down healthcare practices and system malfunctioning over 98000
Americans die and more than one million patients experience injuries every year
According to the National Academies between 30 and 40 of the healthcare costs
which is more than half a trillion dollars annually is used up on overuse underused
mishandling duplication system failures and redundant repetition poor
communication and inefficient healthcare practices
Information technology proposes vast potential benefits to enhance the functioning
and efficiency of US healthcare A completely realized national interoperable
healthcare IT (HIT) system could decrease errors improve communication assist in
eliminating redundancy and supply many other benefits that would guard the patients
and save up to tens of billions of dollars per year The fundamental challenge to
achieving such a system is interoperabilitymdashthe capability of data systems medical
devices and software from different vendors based on various array of platforms to
share patient electronic healthcare records (EHRs) electronic physician orders for lab
tests and drug prescriptions electronic referrals to specialists electronic access to
information about present suggested treatments and research findings and other
information
An important characteristic of a practical HIT system is that it protects the privacy and
confidentiality of patientsrsquo medical information It must also have strong data safety
provisions so that medical information cannot be altered or destroyed by illegal
entities HIT standards must include privacy and security in the original standards
design in order to make sure that these features will be an essential constituent of a
national HIT system
153 Hospital Information System
Various Hospital Information System (HIS) are being developed with the objective of
organizing the treatment process of a patient and allowing doctors and other staff to
perform to their maximum in an organized and efficient manner
It ensures benefits through technological advancement and is a guaranteed return for
investment It is operated in such a way that it is beneficial to both the recipients and
providers of healthcare because it is modeled on a unique combination of a patient
centric and medical staff centric paradigm
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
8
HIS uses a network of computers to gather process and retrieve patient care and
administrative information for easy availability to the users It helps the hospital
authorities by acting as decision support system for developing comprehensive health
care policies It incorporates an integrated computerized clinical information system for
improved hospital administration and patient health care It also helps to provide
updated electronic medical record of the patient These serves as data for research
undertaken by hospital authorities
HIS software is built around a highly optimized core library Application modules are
layered around this core and can be suitably customized for any user specific
requirements
Advantages of maintaining electronic records are
bull Reliable information storage querying and retrieval
bull Easy access to query data as the classification is based on many factors such as
age gender etc
bull Instant information access
bull Efficient and accurate administration of all hospital activities including finance
diet etc
bull Improved monitoring
Example of an effective HIS can be C-DACrsquos Sushrut A hospitalsrsquos administration can be
best explained through this example
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
9
Direct Sourcewwwcdacin
The various modules maintenance and functionality using this HIS can be explained as
1) Out-Patient Management
The out-patient module deals with recording the basic medical treatment details
required for the patient It consists of the following parts
a) Bay Management
This module depends on the registration module for the patients demographic
data
o Paging and Checking of patients in the bay
o Appointment scheduling of patients (normal and investigations)
o Printing of investigation requisition forms
b) Patient Visit Creation and maintenance
o Creation of sessions and recording of complaints and history
o Creation of visit and recording of clinical summary provisional
diagnosis drugs diets and Problem Oriented Medical Records
o Raising Investigation requisition
o Viewing of reports of tests for which results have been entered
o Printing of reports (visit record investigation reports etc)
o Allotment of beds for patients to be admitted
o Appointment Scheduling (normal and investigations)
o Closing of treatment session and recording of final diagnosis
o Making OPD summary and printing it
o Printing all pending investigation reports for a patient till date
o Facility to print duplicate investigation reports
o Printing a report on the total number of old patients handled during a
period
2) Investigation
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
10
For daily hospital activities various types of investigations are carried out Carrying out
number of investigation tests and making the results available promptly is very crucial
for assessing the patients medical status and deciding on the further course of action
The main functions of this module are generating investigation requisitions accepting
investigation requisitions collection of samples for investigations preparation of lab
reports sending samples to laboratories entry of test results and validation of results
Salient Features
bull Raising the Investigation Requisition
bull Sample Collection
bull Printing Packing List
bull AcceptingRejecting the samplesPatient in the Laboratory
bull Entering the details of the Film used in the Investigation
bull Entering the Investigation Results
bull Validation of the Investigation Results
bull Printing the Investigation Reports
bull Viewing of the Investigation results
bull Quality Control Check
bull Keeping track of films Slides issue and returns
bull Tracking of the status of a Test
bull Viewing and Printing of Work-list
3) Billing
The Billing module deals in collection of money for services availed by a patient The
module works in two ways
bull Money can be collected in cash for outpatient services availed
bull Advance can be collected when a patient is to be admitted In this case the
billing module maintains the status of each in-patients account The account is
finally settled when the patient is discharged
The module consists of the following sub-modules Cash Collection Account
Maintenance and Billing Reports
Salient features
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
11
a) Cash Collection
b) Account Maintenance
4) Appointments
This module deals in allotting appointments to patients for a visit to the hospital It
keeps track of available slots in various categories of appointments This module also
deals with cancellation of existing appointments
The module consists of
bull Appointment Scheduling
bull Appointment Cancellation
5) Operation theatre
The Operation Theatre module contains information about the availability of all the
theatres and EquipmentTools Scheduling of operations is the main function of this
module Various departments give the requisition for an operation theatre Various
Functions covered by this module are as follows
bull Operation Theatre Scheduling
bull Raising and validating an operation
bull Preparing an operation dossier
bull Entering Operation record
bull Entering Anesthesia record
6) Blood bank
The Blood Bank is one of the major components of a hospital concerned with various
related activities including donor registration physical examination blood grouping
blood infectious tests component separation blood requisition and cross match The
Blood Bank module provides ready information about blood reservestock daily cross-
matched details total daily blood requisitions and information regarding blood and
donor
7) In-Patient Management
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
8
HIS uses a network of computers to gather process and retrieve patient care and
administrative information for easy availability to the users It helps the hospital
authorities by acting as decision support system for developing comprehensive health
care policies It incorporates an integrated computerized clinical information system for
improved hospital administration and patient health care It also helps to provide
updated electronic medical record of the patient These serves as data for research
undertaken by hospital authorities
HIS software is built around a highly optimized core library Application modules are
layered around this core and can be suitably customized for any user specific
requirements
Advantages of maintaining electronic records are
bull Reliable information storage querying and retrieval
bull Easy access to query data as the classification is based on many factors such as
age gender etc
bull Instant information access
bull Efficient and accurate administration of all hospital activities including finance
diet etc
bull Improved monitoring
Example of an effective HIS can be C-DACrsquos Sushrut A hospitalsrsquos administration can be
best explained through this example
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
9
Direct Sourcewwwcdacin
The various modules maintenance and functionality using this HIS can be explained as
1) Out-Patient Management
The out-patient module deals with recording the basic medical treatment details
required for the patient It consists of the following parts
a) Bay Management
This module depends on the registration module for the patients demographic
data
o Paging and Checking of patients in the bay
o Appointment scheduling of patients (normal and investigations)
o Printing of investigation requisition forms
b) Patient Visit Creation and maintenance
o Creation of sessions and recording of complaints and history
o Creation of visit and recording of clinical summary provisional
diagnosis drugs diets and Problem Oriented Medical Records
o Raising Investigation requisition
o Viewing of reports of tests for which results have been entered
o Printing of reports (visit record investigation reports etc)
o Allotment of beds for patients to be admitted
o Appointment Scheduling (normal and investigations)
o Closing of treatment session and recording of final diagnosis
o Making OPD summary and printing it
o Printing all pending investigation reports for a patient till date
o Facility to print duplicate investigation reports
o Printing a report on the total number of old patients handled during a
period
2) Investigation
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
10
For daily hospital activities various types of investigations are carried out Carrying out
number of investigation tests and making the results available promptly is very crucial
for assessing the patients medical status and deciding on the further course of action
The main functions of this module are generating investigation requisitions accepting
investigation requisitions collection of samples for investigations preparation of lab
reports sending samples to laboratories entry of test results and validation of results
Salient Features
bull Raising the Investigation Requisition
bull Sample Collection
bull Printing Packing List
bull AcceptingRejecting the samplesPatient in the Laboratory
bull Entering the details of the Film used in the Investigation
bull Entering the Investigation Results
bull Validation of the Investigation Results
bull Printing the Investigation Reports
bull Viewing of the Investigation results
bull Quality Control Check
bull Keeping track of films Slides issue and returns
bull Tracking of the status of a Test
bull Viewing and Printing of Work-list
3) Billing
The Billing module deals in collection of money for services availed by a patient The
module works in two ways
bull Money can be collected in cash for outpatient services availed
bull Advance can be collected when a patient is to be admitted In this case the
billing module maintains the status of each in-patients account The account is
finally settled when the patient is discharged
The module consists of the following sub-modules Cash Collection Account
Maintenance and Billing Reports
Salient features
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
11
a) Cash Collection
b) Account Maintenance
4) Appointments
This module deals in allotting appointments to patients for a visit to the hospital It
keeps track of available slots in various categories of appointments This module also
deals with cancellation of existing appointments
The module consists of
bull Appointment Scheduling
bull Appointment Cancellation
5) Operation theatre
The Operation Theatre module contains information about the availability of all the
theatres and EquipmentTools Scheduling of operations is the main function of this
module Various departments give the requisition for an operation theatre Various
Functions covered by this module are as follows
bull Operation Theatre Scheduling
bull Raising and validating an operation
bull Preparing an operation dossier
bull Entering Operation record
bull Entering Anesthesia record
6) Blood bank
The Blood Bank is one of the major components of a hospital concerned with various
related activities including donor registration physical examination blood grouping
blood infectious tests component separation blood requisition and cross match The
Blood Bank module provides ready information about blood reservestock daily cross-
matched details total daily blood requisitions and information regarding blood and
donor
7) In-Patient Management
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
9
Direct Sourcewwwcdacin
The various modules maintenance and functionality using this HIS can be explained as
1) Out-Patient Management
The out-patient module deals with recording the basic medical treatment details
required for the patient It consists of the following parts
a) Bay Management
This module depends on the registration module for the patients demographic
data
o Paging and Checking of patients in the bay
o Appointment scheduling of patients (normal and investigations)
o Printing of investigation requisition forms
b) Patient Visit Creation and maintenance
o Creation of sessions and recording of complaints and history
o Creation of visit and recording of clinical summary provisional
diagnosis drugs diets and Problem Oriented Medical Records
o Raising Investigation requisition
o Viewing of reports of tests for which results have been entered
o Printing of reports (visit record investigation reports etc)
o Allotment of beds for patients to be admitted
o Appointment Scheduling (normal and investigations)
o Closing of treatment session and recording of final diagnosis
o Making OPD summary and printing it
o Printing all pending investigation reports for a patient till date
o Facility to print duplicate investigation reports
o Printing a report on the total number of old patients handled during a
period
2) Investigation
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
10
For daily hospital activities various types of investigations are carried out Carrying out
number of investigation tests and making the results available promptly is very crucial
for assessing the patients medical status and deciding on the further course of action
The main functions of this module are generating investigation requisitions accepting
investigation requisitions collection of samples for investigations preparation of lab
reports sending samples to laboratories entry of test results and validation of results
Salient Features
bull Raising the Investigation Requisition
bull Sample Collection
bull Printing Packing List
bull AcceptingRejecting the samplesPatient in the Laboratory
bull Entering the details of the Film used in the Investigation
bull Entering the Investigation Results
bull Validation of the Investigation Results
bull Printing the Investigation Reports
bull Viewing of the Investigation results
bull Quality Control Check
bull Keeping track of films Slides issue and returns
bull Tracking of the status of a Test
bull Viewing and Printing of Work-list
3) Billing
The Billing module deals in collection of money for services availed by a patient The
module works in two ways
bull Money can be collected in cash for outpatient services availed
bull Advance can be collected when a patient is to be admitted In this case the
billing module maintains the status of each in-patients account The account is
finally settled when the patient is discharged
The module consists of the following sub-modules Cash Collection Account
Maintenance and Billing Reports
Salient features
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
11
a) Cash Collection
b) Account Maintenance
4) Appointments
This module deals in allotting appointments to patients for a visit to the hospital It
keeps track of available slots in various categories of appointments This module also
deals with cancellation of existing appointments
The module consists of
bull Appointment Scheduling
bull Appointment Cancellation
5) Operation theatre
The Operation Theatre module contains information about the availability of all the
theatres and EquipmentTools Scheduling of operations is the main function of this
module Various departments give the requisition for an operation theatre Various
Functions covered by this module are as follows
bull Operation Theatre Scheduling
bull Raising and validating an operation
bull Preparing an operation dossier
bull Entering Operation record
bull Entering Anesthesia record
6) Blood bank
The Blood Bank is one of the major components of a hospital concerned with various
related activities including donor registration physical examination blood grouping
blood infectious tests component separation blood requisition and cross match The
Blood Bank module provides ready information about blood reservestock daily cross-
matched details total daily blood requisitions and information regarding blood and
donor
7) In-Patient Management
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
10
For daily hospital activities various types of investigations are carried out Carrying out
number of investigation tests and making the results available promptly is very crucial
for assessing the patients medical status and deciding on the further course of action
The main functions of this module are generating investigation requisitions accepting
investigation requisitions collection of samples for investigations preparation of lab
reports sending samples to laboratories entry of test results and validation of results
Salient Features
bull Raising the Investigation Requisition
bull Sample Collection
bull Printing Packing List
bull AcceptingRejecting the samplesPatient in the Laboratory
bull Entering the details of the Film used in the Investigation
bull Entering the Investigation Results
bull Validation of the Investigation Results
bull Printing the Investigation Reports
bull Viewing of the Investigation results
bull Quality Control Check
bull Keeping track of films Slides issue and returns
bull Tracking of the status of a Test
bull Viewing and Printing of Work-list
3) Billing
The Billing module deals in collection of money for services availed by a patient The
module works in two ways
bull Money can be collected in cash for outpatient services availed
bull Advance can be collected when a patient is to be admitted In this case the
billing module maintains the status of each in-patients account The account is
finally settled when the patient is discharged
The module consists of the following sub-modules Cash Collection Account
Maintenance and Billing Reports
Salient features
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
11
a) Cash Collection
b) Account Maintenance
4) Appointments
This module deals in allotting appointments to patients for a visit to the hospital It
keeps track of available slots in various categories of appointments This module also
deals with cancellation of existing appointments
The module consists of
bull Appointment Scheduling
bull Appointment Cancellation
5) Operation theatre
The Operation Theatre module contains information about the availability of all the
theatres and EquipmentTools Scheduling of operations is the main function of this
module Various departments give the requisition for an operation theatre Various
Functions covered by this module are as follows
bull Operation Theatre Scheduling
bull Raising and validating an operation
bull Preparing an operation dossier
bull Entering Operation record
bull Entering Anesthesia record
6) Blood bank
The Blood Bank is one of the major components of a hospital concerned with various
related activities including donor registration physical examination blood grouping
blood infectious tests component separation blood requisition and cross match The
Blood Bank module provides ready information about blood reservestock daily cross-
matched details total daily blood requisitions and information regarding blood and
donor
7) In-Patient Management
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
11
a) Cash Collection
b) Account Maintenance
4) Appointments
This module deals in allotting appointments to patients for a visit to the hospital It
keeps track of available slots in various categories of appointments This module also
deals with cancellation of existing appointments
The module consists of
bull Appointment Scheduling
bull Appointment Cancellation
5) Operation theatre
The Operation Theatre module contains information about the availability of all the
theatres and EquipmentTools Scheduling of operations is the main function of this
module Various departments give the requisition for an operation theatre Various
Functions covered by this module are as follows
bull Operation Theatre Scheduling
bull Raising and validating an operation
bull Preparing an operation dossier
bull Entering Operation record
bull Entering Anesthesia record
6) Blood bank
The Blood Bank is one of the major components of a hospital concerned with various
related activities including donor registration physical examination blood grouping
blood infectious tests component separation blood requisition and cross match The
Blood Bank module provides ready information about blood reservestock daily cross-
matched details total daily blood requisitions and information regarding blood and
donor
7) In-Patient Management
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
12
The In-patient module commences when the patient is being allotted a bed in the
ward It deals with the complete treatment of the patient during hisher stay in the
hospital
Salient Features
bull Bed Allotment
bull Inter-departmental Consultation
bull Transfer of patient between wards and beds
bull Requisition of drugs and consumables from the pharmacy
bull Raising investigations and report viewing
bull Maintenance of billing sheets for patients
bull Discharge of patients
8) Registration
Registration of the patient is the foremost activity in the overall Hospital Information
System Every patient who approaches a hospital has to get registered prior to getting
any consultation treatment and investigations done from the hospital
InputScreen Interfaces
bull Capturing Demographic Details
bull Visit Creation for the Old Patients
bull Change of Department
bull Duplicate Card Printing
bull Modification Request
9) Enquiry
This module provides information about all the enquiries received regarding the
hospital and the patients admitted or registered in the hospital The details of the
utilities are outlined in the later part of the write up Eg In-patient enquiry Out-
patient enquiry holiday enquiry etc
10) Master management
The functioning of the Hospital Information System depends on a large set of data that
remains static for a long period of time The Master module is used to enter modify and
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
13
validate the Master data that is used by all the other modules It is the responsibility of
the System Administrator to maintain the integrity of this data Eg of masters
maintained are Department master Designation master Lab master etc
11) Central Sterile Services
The Central Sterile Services Departments (CSSD) main function is to provide sterile
items linen equipment to wards and OTs The CSSD receives reusable equipment
linen from various wards and OTs for sterilization Items are exchanged depending
upon the requirements The linen is sent for washing to the laundry directly or through
CSSD Washed linen from laundry is sent to CSSD for sterilization These sterilized items
are issued to wardsOTs as per the requisition received from their side The CSSD also
prepares linen and dressing material from the cloth in different sizes which are
standardized by hospital management Once the dressing material and linen is
prepared new item details are entered into the system and stocks are updated
accordingly
12) Diet Kitchen
The functionality of the kitchen module is to manage the patients meal services Its
features include Meal scheduling Meal cancellation Diet requisition Slip Diet
Cancellation Report Late admission report and Therapeutic Diet
13) Bio-Medical Engineering Department
The Bio-Medical Engineering Department (BMED) module keeps track of the details of
the Bio-medical equipment installed at SGPGI The details include equipment code
category department name location and vendors name and purchase details This
module also handles complaints and service details of different equipment This
module interacts with the central stores module for equipment receipt
14) Central Stores
This module deals with Hospital EquipmentMaterialInventory Purchase and Supply to
different Departments Requisitions for different itemsequipment are sent to this store
from different departments and accordingly the CSD issues itemsequipment to various
departments The CSD also maintains records of purchases stock and supplier list
itemequipmentmaterial master tables and also takes care of the inspection details
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
14
15) Pharmacy management
The Pharmacy Module deal with the maintenance of drugs and consumables in the
hospital The functions of this module include online drug prescription inventory
management of drugs consumables and sutures This module optionally handles the
billing of drugs consumables and sutures if required The Pharmacy module ensures
that there is a round the clock availability of a sufficient quantity of drugs and
consumable material for the patients in a mode that neither hinders efficient clinical
work nor it becomes a threat to the survival of the Pharmacy
12) Patient Medical Records
The Patient Record Management Module is crucial in the overall integrated hospital
management system The rationale behind computerization of PMR is to maximize the
usage of the patients medical information This improves patient care as it functions as
a central source of information for communication between health care providers
covering the patients history observation diagnosis and therapeutic conclusions and a
wide variety of unstructured documents and information Moreover it facilitates
external linkage possibilities with health care providers and identification of clinical
events that need attention It can solve many of the logistics problems of archiving
retrieving tracing and finding out paper based medical records Various reports like
discharge summary diagnostic classification as per international classification of
diseases statistical report according to diagnosis age sex geographical area and other
parameters of the patient surgeon index wise reporting hospital statistics and analysis
of cases for research purpose are generated PMR updates the patients file with the
information like diagnosis details and test results and final patient status
154 EHR (Electronic Healthcare Records)
An EHR is the clinical component that records the credentials of patientsrsquo medical
histories symptoms diagnoses treatments etc Thus EHRs contains the financial
administrative research and educational characteristics of patient care As represented
in the figure below the end users of HER includes hospitals ambulatory care clinics
primary care offices physicians nurses etc ancillary departments like radiology
laboratory pharmacies etc patients through a Personal Health Record (PHR) portal
public health departments and payers (insurance companies) Moreover
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
15
Pharmaceutical companies may even be involved in evaluating data from EHRs
However the users have access to only those aspects of the EHR for which they are
approved EHRs from different hospitals and physician offices need to be interoperable
to encourage local regional national and global sharing of information Just as an ATM
card can be read in New York and New Delhi EHRs should be able to connect globally
have the capacity to access and share data as needed and enhance the quality of
patient care
Source Datamonitor
EHRs will assist in changing the healthcare industry from current reactive to more
proactive up to date and leverages planned workflows The quality of care patients
obtain within conventional healthcare settings will progress the information available
to clinicians will increase and the pace at which association for patient care public
health examination and medical research occurs will be immediate
The following factors are leading the implement EHRs in the market
bull Improving the quality of care is a main concern for healthcare organizations
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
16
EHRs are part of the explanation to improving patient security in the healthcare system
For example medication errors in particular accounted for a considerable proportion
of the number of avoidable errors that take place on a day to day basis in healthcare
settings EHRs deal with many of the areas where medication errors are likely to
happen At the most fundamental level an electronic system reduces the problems of
illegibility A carefully typed drug prescription is expected to be filled appropriately
than one that is hurriedly scribbled With the addition of decision-support tools doctors
are capable to now check for likely complications with other prescriptions while
recommending medication or rapidly confirm the distinction between two medications
that have like names These are only a few of the various benefits EHRs can provide that
current paper based systems cannot offer
In addition to reducing medical errors EHRs raise the value of care by varying the way
in which care is distributed and improving the general patient experience At present
with paper charts only one doctor can use a patientrsquos record at one point Moreover at
the point of cure patient files are often incomplete a part of the record may be in the
lab the radiology department or another physicianrsquos office pending certification As a
result of this lack of management diagnoses and treatment plans are made on
incomplete information Various medical tests have to be repeated because the results
have been lost With EHRs several providers are capable to interpret and modify patient
records improving communication between clinicians Files are no longer misplaced
misfiled or left behind EHRs permit providers to expend less time searching for fresh
lab tests or documentation from other physicians and spend more time with the
patients themselves Increased access to information with physician notes lab results
x-rays and prescriptions all at the reach of the doctors aids them in making better
appropriate clinical decisions and improve patient care EHRs also improve the
scheduling and billing processes Tasks like recovering patient files become less time
consuming leading to faster admission of patients Regardless of the costs and risks of
breakdown the skill to improve patient care is motivating healthcare organizations to
employ EHRs
bull Government initiatives are increasing
As a result of the impact EHRs have on improving the quality of care governments all
over the world are supporting the implementation of EHRs UKrsquos National Health Service
(NHS) formed an organization within the Department of Health known as the
Connecting for Health in 2005 Its objective is to convey the National Programme for IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
17
(NPfIT) NPfIT proposal consist of the Care Records Service arrangement prescribing
infrastructure email picture archiving and communications systems (PACS) as well as
the Quality Management and Analysis System As the NHS is supporting all these
projects these IT systems have and are being put into practice No other country has so
far achieved a countrywide EHR system than the UK because no other government has
spent as compared to UK
In the US government support has been mainly through improved consideration to
healthcare technology to encourage awareness In 2004 President Bush issued an
Executive Order to set up the National Health Information Technology Coordinator in
the Department of Health and Human Services and lay down an aim for every American
to have right to use to an EHR by 2014 To aid rural hospitals execute EHRs the Office of
Rural Health Policy at the federal Health Resources and Services Administration
awarded $16m to the Minnesota Health Department Similarly the state of California
will offer $25m in grants to healthcare technology projects (EHRs as well as other
healthcare technology solutions) in underserved areas of the state
bull Other healthcare players will encourage late adopters to implement EHRs
The numbers of providers who have not yet implemented EHRs are decreasing but
there are still a group of late adopters These late adopters badly influence the
efficiencies and return on investments (ROI) of EHRs for those who have already
implemented EHRs The full advantages of EHRs will not be recognized until every
provider is linked Having an EHR that is not interoperable is like being the only person
with a phone and thus not being able to call anyone Increased competition and the
possibility of decreasing damages will drive providers to adopt EHRs and regard them
as very important to their practice as their stethoscopes Competition plays an
additional role in the organizations with an efficient EHR solution and will catch the
attention of younger providers and increase employee satisfaction and retention The
fact that everyone else has an EHR should persuade the late adopters that they must
have one as well
Furthermore recommendation to hospitals with better EHR systems will increase
Employers and patients will promote EHR implementation if they choose which
doctors and hospitals to go to based on the technologies in use
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
18
155 Nature and Scope of Present Trends in IT and Health
Healthcare needs and desires cannot be met in most of the countries because of the
size of the worldrsquos population and the prevailing structures of resource distribution
There are numerous disagreements between various countries for making and
observing policies of global trade in healthcare goods and services
Information and communication technologies can transform healthcare system
Through the accurate policy choices IT enables the support of new entry of human
connectivity and is a powerful means of global union through cross-border supply of
services IT enables new opportunities for production of knowledge and trade in it for
direct economic benefits IT is the only factor of production which is not subject to the
economic laws of diminishing returns The international distribution of new knowledge
and best practices establishes new ways of enhancing the performance of health
systems
The most important aspect of IT is its ability to permit reliable storage recovery and
immediate transfer of text sounds images and numbers as audio visual and data
communications This substitutes the face-to-face contact and transportation As a
result of this the resources and needs connect easily and add new links to productive
capacity in all aspects of healthcare-development delivery and administration
IT touches all aspects of healthcare and at many different points of contact These are
(1) ITrsquos role in design of healthcare products and services
(2) ITrsquos impact on design of healthcare systems
(3) Information power effects
(4) Its facilitating role in strengthening public-private partnerships
(5) IT-induced vulnerabilities and IT-aggravated risks and
1551 ITrsquos role in design of healthcare products and services
IT has formed prospects for optimizing connections between domestic markets and
exportsimports which is represented in the design of healthcare products and services
The idea of Telemedicine thus came out as the practice of using audio visual and data
communications for medical consultations diagnosis cure nursing care medical
education and transmission of medical data with a broader model of lsquoTeleHealthrsquo which
contains Telemedicine and healthcare management examination literature and access
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
19
to information from a distance The concept of E-health has slowly emerged to illustrate
the joint use of electronic communication and information technology to facilitate
transfers and interactivity The latest requirements of speed economies of scale
standards simulation and safety have quickly changed healthcare into an information-
based science driven by IT New medicines and treatments develop more rapidly and
enhanced with cross-border distribution of work across time-zones and instantaneous
clinical testing in trials covering a wider geographical area all of which is IT enabled
On-line discussion by patients and doctors through websites and email distance
recommendations urgent evacuations and advance broadcast of images and data of
patients from ambulances can decrease lead times of involvement in emergency wards
of hospitals Treatments managed in a joint mode distance examination of recovering
patients risk estimation by insurers distance consultations on indications revealed by
patients and comments noted by doctors with the help of transferable data from image
scanning machines processing of medico-legal documents and cross-border
networking for TeleEducation are some of the ways in which ITrsquos involvement to new
products and services is growing quickly Applications like TeleEducation for medical
degrees of well-known universities in collaboration with local institutions and for
continuing medical education of professionals in hospitals medical colleges and
healthcare centers have immense demand in developing countries
Outsourced healthcare management operations include medical transcriptions
invoicing collections purchases and inventory management accounting payroll
management continuing education networks linking hospitals and medical schools
surveys and research networks currently are a higher section of domestic business and
trade where ITrsquos function is important and rising
These opportunities symbolize possible services exports not only amongst developed
countries like among Norway and Sweden for prenatal checkups and nursing care in
Lapland or between Australia and Canada for TeleConsultations between doctors but
also from developed to developing countries as Japan to Thailand USA to Mexico
UK to Kenya France to Ivory Coast and Singapore to Indonesia for TeleDiagnostics and
TeleRadiology) from developing countries to developed countries such as
SrilankaIndia to UK USA Australia and New Zealand for healthcare organization
services which could in future be extended to TeleDiagnostics when professional
qualifications are jointly documented or coordinated and among developing countries
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
20
such as Bhutan Thailand Argentina Nigeria India Brazil China Nepal Bangladesh
Tanzania for a range of telemedicine applications
In Japan and Finland initial warning signalling of communicable disease plague is done
from database searches of physicians trying to identify from signs at the time of the
occurrence of disease This type of IT application could be transferred to any
developing country allowing faster involvement when epidemics break out though
protection would be required to guarantee it does not cause panics or false alarms
1552 ITrsquos impact on design of healthcare systems
IT facilitated new ways of working and managing work locally nationwide and
worldwide
IT is an essential concern in the design of public health systems in less developed
countries where governments require to concurrently following schedule associated to
healthcare development and trade Declining budgets and rising expenses of
healthcare support these innovations also in developed countries This has
considerably improved trade potential Medical expenses in OECD countries have risen
to over 10 per cent of GDP and could reach 15 per cent in the next decade High cost
medical procedures increased long life ageing populations and expensive medicines
are the chief cause patients national public health systems and health safeguarding
organizations seek cross-border supplies offering more beneficial pricequality ratios
Within household economies of USA Canada and Japan TeleMedicine services halved
conventional expenses and improved the efficiency of medical professionals
1553 Nature and scope of information power granted by IT
New networks contracts and licenses organization structures control systems and
administration processes facilitated by IT increase choices and decrease response times
for all concerned Patients doctors hospitals pharmacies statutory health authorities
and health insurers can quickly benefit regulate to and propose new responses
interactively and reorganize their tasks towards each other Information power
encourages new ways of exercising power power and accountability to appear
approximately combinations and tradeoffs involving choice costs effectiveness as the
criteria by which performance is judged Performance comparisons promoted during
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
21
honesty and responsibility elevates the incentives for private and public health systems
to participate and execute better Hospitals medical schools pharmaceutical
companies related enterprises as well as local health authorities and health journals
and advisory services have all developed and sustain web pages available during
internet About 25 per cent of the content of the World Wide Web tackles with health
and health-related topics covering traditional and interchange healthcare possibilities
which have extended choice to a great deal 21 Millions of individuals visit world wide
web sites for information which would facilitate them eat intelligently discover to
implement their bodies and to find out other healthcare information IT enables links to
nutrition diet exercise primary healthcare ante-natal and post-natal care hygiene and
sanitation to be located in the proximity of other healthcare and medical information
with obvious synergies
1554 ITrsquos facilitating role in strengthening public-private partnerships
Private sector participation in financing production and delivery of healthcare products
and services is a welcome addition to the resource-starved healthcare sector but also a
challenge to the regulation of public health and in ensuring equitable access to the
poor and needy The sharing of information about facilities performance resources
costs and prices among health authorities planners contributors governments service
providers and patients is an important aid to promoting better management of
healthcare systems with shared perspectives developed through interactive
communications This reduces the chance of missing opportunities of trade promotion
in healthcare that require businesses and governments to act in concert The capacity
of different people and organizations to work together across complex networks is an
important element in novel and experimental advances If communities of expertise
can be connected and resources mobilized together with public interest political
energies and accountability IT diffusion could play an important role in public-private
partnerships in managed healthcare Success in any form of accountable and
responsible public-private partnership is based on ongoing reviews feedbacks and
consultations where informed participation is the key to success IT connectivity
provides an interactive platform to exchange ideas and information at low cost which
encourages participation and acts against exclusion By this process IT facilitates
participation in collaborations by spawning communications networks with strong
incentives to move away from isolated systems towards risk syndications and risk
exchanges harvesting value through designs of communications networks Aided by IT
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
22
the success of Mercks Ivermectin drug donation for curing river blindness enabled a
hundred million people to be treated in 31 countries with credibility of the programme
based on communications networks which enabled wide participation and lots of
feedback This success later spawned one of the biggest public-private partnerships
when Merck joined hands with the Gates Foundation for more such initiatives
In contrast Glaxo-Wellcomes anti-MalariaM alarone drug donation programme in
Kenya suffered from inadequate communication and participation and lack of sufficient
information to conduct a reasoned discourse Failures experienced in drug donation
programmes due to communication gaps could be easily remedied by IT IT
connectivity would have enabled facts of the Malarone case to be known at the time it
happened with scope for timely intervention by all concerned instead of the public
remaining unaware for four years until details were published by scholarly journals like
Lancet Electronic archiving accessible through internet could simplify dissemination of
new knowledge published by scientific journals
The core role of IT in healthcare may be understood from the way designs of healthcare
development and delivery enabled and supported by IT include or exclude people and
encourage or discourage their participation in influencing decisions about allocation of
healthcare resources Participation is a vital aspect of healthcare because health
consumption requires participation in its production at every level starting from
individual persons (diet hygiene lifestyle belief and trust in one or more medical
systems) to communities (safety pollution control sanitation public hygiene) and
nations (healthcare standards budgetary allocations medical education support to
research and innovation in diagnosis and treatment and availability of medicines)
rendering it uniquely amenable to communicative technologies horizontally and
vertically in and between these aggregations
Public-private partnerships are also required to cope with trading in bioinformatics and
clinical databases Significant transactions costs arise when contributions are sourced
from a wide range of value creators using different platforms of data transfers and with
multiple claims to proprietary rights over fragments of a whole process before a
marketable product arise This creates incentives for venture capital pharmaceutical
firms biotech start-ups and the State (and its marketwise counterparts such as health
maintenance organizations) to make new forms of partnerships in predictive medicine
and treatments Alliances of universities and research centers with drug developing and
clinical trial enterprises are being established within developed and developing
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
23
countries and also between organizations in developed and developing country
locations IT-intensity sustains such networks contributing to efficiency and equity
through rationalization of financial constraints as well as non-financial constraints
1555 IT-induced vulnerabilities and IT-aggravated risks
IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization Connection
speeds are constrained by availability of bandwidth spectra and the risk of data loss
from contamination by viruses and bugs can only be minimized but not altogether
eliminated While information that IT produces is easily commoditized much of the
knowledge that IT driven biotechnology incubates is tacit and not easily reducible as
information This is the reason that biotech requires science parks and trustful
networking anchored in a location Placing information on the web poses risks to
ownership of intellectual property Nor can all information belong to everyone being
unsustainable even in its elements without being hosted or sponsored IT products are
excludable divisible and own able through introduction of filters but cyberspace does
not create a domain governed from within itself insulated from other jurisdictions The
reliance on IT obliges adaptation to ever-changing new technical norms and to new
rules introduced by regulators or censors
Policies and safeguards need to be envisaged to harmonize private and public interest
so that IT is not used as a tool to propagate harmful substances and drugs There could
be four different ways in which IT as a media channel could be protected from
undesirable traffic
1 International legal agreements on e-commerce prohibiting certain products and
services as ldquoglobal public badsrdquo from the purview of e-commerce
2 Introduction of rules by regulators with enforceable penalties
3 The use of IT itself to neutralize the canvassing of ldquosins and badsrdquo with counter-
campaigns disclosing more information on health hazards
4 Censorship of cyberspace through filters
IT has enabled certain kinds of abuses that would have previously not been possible to
execute on a large scale Pharmaceutical firms provide incentives to pharmacies to sell
prescription drugs over the counter without prescriptions in less developed countries
IT has made it possible for chemists pharmacies and extension counters of clinics and
hospitals to build databases and push products using retail store models of incentives -
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
24
something that would be impossible in developed countries where firms target
doctors not individual chemists or pharmacies
New vulnerabilities point to the need for policy safeguards to deal with the following
problems
(a) Rights to privacy and personal data protection are easily breached because
healthcare databases have to be kept open for updating old records and for
initiating new records and entries So confidentiality cannot be secured by
coding the data or disconnecting the data from personally identifiable features
Patients could lose trust in the confidentiality of their conversations with their
doctors unless this problem is solved Demands of payment for parting with
bio-information could arise
(b) Medical databases are easily linkable to databases of genealogy castes tribes
clans ethnicity and genetics The principle that such data be stored only at its
place of origin and used only for the original purpose for which it is collected is
difficult to enforce Personal data on whole nations and ethnic groups could be
exploited in ways that endanger public health (Mathur 2002) Without
enforceable international agreements no individual or social institution is in
any position to supervise the use of healthcare databases In the hands of
mercenaries and rogue states healthcare databases could be misused to trigger
complex humanitarian emergencies or for fostering permanent dependencies
using biopower as a means of disruption
(c) The scientific and commercial value of health databases is limited to those who
have the means to maintain and update these databases and link them to other
databases in their possession This could accentuate the information and
technology gaps between developed and less developed countries
(d) IT enables decoding of personal data using genotypes and phenotypes as
personal identifiers and the design of novel organisms against which vaccines
or antibiotics would be useless When private information held in public
databases is commercially traded by privatising public domains rights of
natural persons get transposed with rights of artificial juridical entities Since
intellectual property rights are private rights international regimes for e-
commerce in healthcare and consumer protection are needed for what remains
outside the public domain
(e) If it is known that normal data protection controls can be easily bypassed by
powerful interests in a vital area like health in any particular country it would
also have consequences for trade and development in other sectors due to loss
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
25
of confidence in that countryrsquos capacity to provide adequate data protection for
business secrets and intellectual property rights
Doctors and patients benefit from the way IT enables records to be safely stored
efficiently retrieved easily updated and quickly transferred IT promotes awareness
People easily obtain information concerning diseases treatments and facilities
Discerning consumers get to understand their own responsibility as co-producers of
their health and to evaluate choices Studies have established that small inputs of
TeleHealth resources contributed to huge gains in access to healthcare for consumers
in Bhutan Ethiopia Sri Lanka South Africa Argentina Mozambique Taiwan Saudi
Arabia Thailand and Jordan
156 Information Technologyrsquos Role in Life Sciences Research amp Development
In recent years innovations where IT and the life sciences converge have created vast
quantities of data The development of automated DNA sequencing and other
innovative methods have reduced the costs and time needed to discover the genetic
makeup of various organisms Additionally innovations such as high-throughput
screening and micro-arrays are enabling studies of gene and protein functions (ie
genomics and proteomics)
The expanding complexity and diversity of information also pose new challenges For
example data produced from studies of protein and gene function and interaction can
require the consolidation of information in various formats and from diverse sources
Additionally data may not be in a standard or readily usable format particularly if they
are not available electronically or are text-based information from scientific literature
patents and clinical trials Critical biological information also is found throughout
various scientific disciplines such as the chemical sciences The ability of researchers to
manage and analyze these diverse and extensive data is critical to the future success of
life sciences RampD
The needs described above have spawned the research field ldquobioinformaticsrdquo which
focuses on the use of IT to collect organize store interpret share and analyze
biological data Developments in bioinformatics will be critical for facilitating RampD in
areas such as human and animal health agriculture industrial processing natural
resource recovery and environmental remediation Figure 61 illustrates the IT and life
sciences components of bioinformatics
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
26
Bioinformatics Use Information Technology to Manage and Analyse Information
Generated by the Life Sciences
Researchers are exploring strategies to increase computing capabilities for diverse life
sciences purposes such as computer-based drug design One strategy is to expand the
potential of supercomputers Another is to unify computing resources through
development of global or grid computing networks These networks link the power of
individual PCs or supercomputers Researchers have achieved teraflop speeds (a trillion
floating point operations per second) using these grid networks In the future they
hope to achieve petaflop speeds (a thousand trillion floating point operations per
second)
The Internet is a particularly valuable tool for life sciences researchers especially for
those with limited resources It enables researchers to tap into data software and
computing power
New software developments also promise life sciences researchersrsquo the ability to
acquire format search and analyze disparate data sources and types Data mining and
visualization software are improving scientistsrsquo ability to screen data and identify
important relationships One software analysis tool 3-D molecular modelling facilitates
studies of the function and relationships between biological molecules These analysis
tools are enabling scientists to conduct some research at the computer instead of at the
lab bench reducing the time and costs of life sciences RampD
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
27
Standardization enables researchers to link different databases and software programs
thereby making the discovery process more efficient Standardizing scientific
nomenclature databases and software helps researchers exchange and analyze
information more easily Researchers also benefit from the development of technical
and computational standards for hardware and software
Given the diversity of and rapid developments in life sciences databases and software
standardization is too difficult and costly for any organization to undertake alone To
overcome this obstacle the Interoperable Informatics Infrastructure Consortium (I3C)
was founded in 2001 to collectively address some standardization problems I3C is an
international consortium that includes life science and IT participants from private
industry government institutions academia and other research organizations They
develop and promote ldquoglobal vendor-neutral informatics solutions that improve data
quality and accelerate the development of life science productsrdquo I3Crsquos
accomplishments include standards developed to identify and access biologically
significant data and a method that simplifies data retrieval from multiple databases
157 Bioinformatics Assists Drug Discovery and Development
Bioinformatics is improving the RampD process in drug discovery and development IT
tools have become important for managing and screening genetics data and for
modelling outcomes in drug development New developments in bioinformatics and
genetics such as pharmacogenetics (ie the study of the relationships between
diseases genes proteins and pharmaceuticals) will enable researchers to identify
quickly a patientrsquos genetic predisposition to contract certain diseases as well as their
potential drug response
Costs of drug discovery have been escalating It now costs $900 million and takes 15
years on average to develop a new drug Clinical trials constitute most of these costs
Additionally about 75 percent of drug development costs can be attributed to failures
Analysts anticipate that advances in IT and the biological sciencesmdashsuch as the
computer-enabled ability to quickly screen drug candidates and predict drug
responsesmdashcould lower failure rates substantially reducing costs by as much as one-
third and time by as much as two years
158 The Indian Perspective
The Indian healthcare sector is today lagging behind in IT adoption The reports show
that the rural sector is the most affected as Indian healthcare is not spread onto small
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
28
hospitals though the rate of expansion is very rapid The main reason for slow adoption
of IT in health industry is due to lack of regulations and standardization and the lack of
professionalism Another major reason is the fragmented nature of the Indian
healthcare
Today however the Indian healthcare landscape is changing in the urban cities and IT
is poised to revolutionize healthcare in India The technology adoption is very rapid due
to severe competition The big Indian hospitals like Apollo Fortis Wockhardt Manipal
earlier believed that IT can only help in automation of the medical industry but now
they believe that IT can help in cost reduction and increase return on investments
Healthcare has realized the value of IT due to the changing regulations and framework
India spends about 30 million $ on healthcare industry and the cost is expected to
increase more than double fold in next ten years
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
29
Summary
bull IT investment offers an environment for a new level of care to exist
bull Information technology (IT) has significantly reduced the costs improved the
speed and enhanced the efficiency of life sciences research and development
(RampD)
bull The maximum advancements of IT will be felt on release of healthcare
bull Information technology presents huge potential benefits to US healthcare
bull The major difficulty in the adoption of a nationwide interoperable healthcare
information technology (HIT) system is the lack of vigorous commonly
accepted technical standards
bull Though the United States is the most technologically advanced nation in the
world the US healthcare system persists to depend on pen and paper for the
bulk of its information requirements
bull Information technology proposes vast potential benefits to enhance the
functioning and efficiency of US healthcare
bull An important characteristic of a practical HIT system is that it protects the
privacy and confidentiality of patientsrsquo medical information
bull An EHR is the clinical component that records the credentials of patientsrsquo
medical histories symptoms diagnoses treatments etc
bull EHRs will assist in changing the healthcare industry from current reactive to
more proactive up to date and leverages planned workflows
bull As a result of the impact EHRs have on improving the quality of care
governments all over the world are supporting the implementation of EHRs
bull In the US government support has been mainly through improved
consideration to healthcare technology to encourage awareness
bull IT has formed prospects for optimizing connections between domestic markets
and exportsimports which is represented in the design of healthcare products
and services
bull IT enables new ways of working and organizing work locally nationally and
globally
bull Public healthcare systems can be significantly rationalized with IT
bull The drug discovery process in the new biotechnologies is IT-intensive
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
Certificate in Health Care amp Life Sciences ndash L1 TCS Business Domain Academy
30
bull According to the National Human Genome Resource Institute in USA genes
contain codes for more than 50000 proteins in the human body and drugs on
the market presently target only 10 per cent of these
bull Private sector participation in financing production and delivery of healthcare
products and services is a welcome addition to the resource-starved healthcare
sector but also a challenge to the regulation of public health and in ensuring
equitable access to the poor and needy
bull IT is distinguishable from other technologies because it is process oriented and
transformative in its effects on production consumption and organization
bull IT has enabled certain kinds of abuses that would have previously not been
possible to execute on a large scale
bull In recent years innovations where IT and the life sciences converge have
created vast quantities of data
bull Bioinformatics is improving the RampD process in drug discovery and
development
31
31