A New Stereocontrolled Approach to Fused Polycyclic Compounds Containing a Diketopiperazine Ring.

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2006 Fused pyrimidine derivatives R 0515 A New Stereocontrolled Approach to Fused Polycyclic Compounds Containing a Diketopiperazine Ring. — The stereoselective alkylation of readily available lactim ethers (I) and (V) is investigated in continuation of studies on the synthesis of analogues of the multi-drug resistance reversal agent N-acetylardeemin. — (HERNANDEZ, F.; AVENDANO*, C.; SOELLHUBER, M.; Tetrahedron: Asymmetry 16 (2005) 19, 3160-3169; Dep. Quim. Org. Farm., Fac. Farm., Univ. Complutense, E-28040 Madrid, Spain; Eng.) — Nuesgen 08- 128

Transcript of A New Stereocontrolled Approach to Fused Polycyclic Compounds Containing a Diketopiperazine Ring.

Page 1: A New Stereocontrolled Approach to Fused Polycyclic Compounds Containing a Diketopiperazine Ring.

2006

Fused pyrimidine derivativesR 0515 A New Stereocontrolled Approach to Fused Polycyclic Compounds Containing a

Diketopiperazine Ring. — The stereoselective alkylation of readily available lactim ethers (I) and (V) is investigated in continuation of studies on the synthesis of analogues of the multi-drug resistance reversal agent N-acetylardeemin. — (HERNANDEZ, F.; AVENDANO*, C.; SOELLHUBER, M.; Tetrahedron: Asymmetry 16 (2005) 19, 3160-3169; Dep. Quim. Org. Farm., Fac. Farm., Univ. Complutense, E-28040 Madrid, Spain; Eng.) — Nuesgen

08- 128