A MAJOR REVISION Coming in Marchl A New Coauthorl A New Organizationl A New Illustration Program

l Many New Topics (see inside) . . . . . . . . . . . . . . . . . . . . . . . . . . .

ABOUT THE BOOK

Extensively rewritten and reorganized, this new edition of Evolution fea-tures a new coauthor: Mark Kirkpatrick (The University of Texas at Austin) offers additional expertise in evolutionary genetics and genomics, the fastest-developing area of evolutionary biology. Directed toward an under-graduate audience, the text emphasizes the interplay between theory and empirical tests of hypotheses, thus acquainting students with the process of science. It addresses major themes—including the history of evolution, evolutionary processes, adaptation, and evolution as an explanatory framework—at levels of biological organization ranging from genomes to ecological communities.

New in This Editionl Genomic perspectives on evolution are strengthened throughout.l The content has a stronger focus on human evolution: an entirely new chapter on the topic (Chapter 21, The Evolutionary Story of Homo sapiens), and new examples throughout the book.l Many chapters have been rewritten from the ground up.l The book has been entirely reillustrated in a clean, contemporary style that enhances the content.l A new Appendix, A Statistics Primer, introduces the concept of a probability distribution, reviews how statistics are used to describe populations, looks at how we estimate quantities, and discusses how hypotheses are tested. It ends with a brief overview of two major frameworks of statistical analysis: likelihood and Bayesian inference. Math is kept to a minimum.

March 2017 l 594 pages (est.) l 516 illustrations (est.)ISBN 978-1-60535-605-1 l casebound$137.95 Suggested list price l $110.36 Net price to resellers

Print Editionl Order from our website for a 15% discount from suggested list price. ($117.26)l Free standard ground shipping to U.S. addresses.l Orders usually ship in 1–4 business days.l Offer not available to resellers.

eBookl Suggested list discounted 50% from bound book list price for a 180-day subscription. ($68.98)l Suggested list discounted 15% from bound book list price to own permanently. ($117.26)l Formats include BryteWave, RedShelf, VitalSource, and YUZU.l All major mobile devices are supported.

Prices subject to change May 1 and November 1, yearly.

Looseleaf Editionl Discounted 35% from suggested list price of the bound print edition. ($89.67)l Additional 15% discount with free shipping at our website also applies. ($76.22)

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l A New Coauthorl A New Organizationl A New Illustration Program

l Many New Topics (see inside) . . . . . . . . . . . . . . . . . . . . . . . . . . .

Evolution, Fourth EditionDouglas J. Futuyma and Mark Kirkpatrick

ABOUT THE AUTHORS

Mark Kirkpatrick is the Painter Centennial Professor of Genetics in the Department of Integrative Biology at the University of Texas at Austin. He received his B.A. in Biology from Har-vard in 1978 and his Ph.D. in Zoology from the University of Washington with Monty Slatkin in 1983. Dr. Kirkpatrick has received a Guggenheim Fellowship (1997) and a Poste Rouge Fellowship (France, 1997). He is a Fellow of the American Academy of Arts and Sciences (2008), and of the American Association for the Advancement of Science (2016). Dr. Kirkpatrick received the Sewall Wright Award from the American Society of Naturalists (2014). He has served as Associate Editor of The American Naturalist, Theoretical Population Biology, and Genetics, and on the Ed-itorial Boards of The Annual Review of Ecology, Evolution, and Systematics and Proceedings of the Royal Society of London B. Dr. Kirkpatrick’s research interests are in evolutionary genetics. He has worked on sexual selection, quantitative genetics, speciation, and species ranges. Current research topics include the evolution of sex deter-mination and chromosome rearrangements.

For the StudentCompanion Website (evolution4e.sinauer.com)The Evolution, Fourth Edition Companion Website features review and study tools to help students master the key concepts presented in the textbook. Access to the site is free of charge, and requires no access code. (Instructor registration is required in order for students to access the quizzes.) The site includes the following resources:l Chapter Outlines and Summaries: Concise overviews of the important topics covered in each chapter.l Data Analysis Exercises: These inquiry-based exercises involve students in working with data and analyzing methods and conclusions from published papers.l Simulation Exercises: Interactive modules that allow students to explore many of the dynamic processes of evolution, and answer questions based on the results they observe.l Online Quizzes: Quizzes that cover all the major concepts introduced in each chapter. These quizzes are assignable by the instructor.l Flashcards: Easy-to-use flashcard activities that help students learn and review all the key terminology introduced in each chapter.l The complete Glossary

For the Instructor (available to qualified adopters)Instructor’s Resource LibraryThe Evolution, Fourth Edition Instructor’s Resource Library includes a variety of resources to help you develop your course and deliver your lectures. The IRL includes the following:l Textbook Figures and Tables: All the figures (including photographs) and tables from the textbook are provided as JPEGs, reformatted and relabeled for optimal readability when projected.l PowerPoint Presentations: For each chapter, all of the figures and tables are provided in a ready-to-use PowerPoint presentation that includes titles and full captions.l Answers to the textbook end-of-chapter Problems and Discussion Topicsl Quiz Questions from the Companion Websitel Data Analysis and Simulation Exercises from the Companion Website, with answers

Online Quizzing A set of online quizzes is available via the Companion Website. These quizzes can be assigned or released for student self-study, at the instructor’s discretion. Instructors can also add their own questions to the quizzing system, to create custom quizzes. Results can be viewed online or down-loaded for use in gradebook programs. (Instructor registration is required for student access to the quizzes.)

Douglas J. Futuyma is Distinguished Profes-sor in the Department of Ecology and Evolution at the State University of New York at Stony Brook. He received his B.S. from Cornell Univer-sity and his Ph.D. in Zoology at the University of Michigan with Lawrence Slobodkin. Dr. Futuyma is the author of three previous editions of Evo-lution, as well as three editions of its predeces-sor, Evolutionary Biology. He received the 1997 Sewall Wright Award of the American Society of Naturalists and the 2012 Joseph Leidy Award of the Academy of Natural Sciences of Drexel University (Philadelphia). Dr. Futuyma has served as President of the Society for the Study of Evolution, the American Society of Naturalists, and the American Institute of Biological Scienc-es, and was elected a Fellow of the American Academy of Arts and Sciences in 1996 and the National Academy of Sciences in 2006. He has served as Editor of Evolution and is currently Ed-itor of the Annual Review of Ecology, Evolution, and Systematics. In 2013, he was recognized as Honorary Doctor by the National University of Mongolia. An avid naturalist, his major research interests include evolution of interactions among insects and plants, speciation, and evolution of community structure.

ABOUT THE AUTHORS MEDIA AND SUPPLEMENTS

CHAPTER HIGHLIGHTS Chapters marked by an asterisk* have been entirely rewritten. Elements in blue italics have been extensively revised from the Third Edition.

l Molecular signatures of adaptationl Evolutionary side effects and tradeoffs: pleiotropy and linkagel Deleterious mutations and the mutation load in humansl The evolution of mean fitness

6. Phenotypic Evolution*l Less technical approach to quantitative traits and selection

l How do quantitative traits change by evolution of allele frequencies?l Selection gradients: Interpretation, measurement, and values in naturel Expanded treatment of artificial selectionl Evolutionary rescuel QTL (quantitative trait locus) mappingl The genetics of quantitative traits, within and between species

1. Evolutionary Biologyl More succinct history of evolutionary biologynct history of evolutionary

2. The Tree of Lifel Combines previous chapters on phylogeny and patterns of evolutionl Elementary method of phylogenetic inferencel Not only organisms have phylogenies

3. Natural Selection and Adaptationl More streamlined than in previous editionsl Adaptive evolution observedl Selfish genes and unselfish behaviorl Imperfections and constraintsl Natural selection and the evolution of diversity

4. Mutation and Variation*l Smoother integration of Mendelian and population geneticsl A modern view of recombination that covers both prokaryotes and eukaryotesl Somatic mutation and cancerl Nongenetic inheritance

5. The Genetical Theory of Natural Selection*l A simplified approach to the genetics of natural selectionl Examples of recent adaptation in humans

l Detecting selection using genomic data from humans and other species

8. Evolution in Space l Causes and consequences of gene flowl Gene flow vs. selectionl Gene swampingl Estimating gene flow from genetic datal The evolution of dispersal

CHAPTER HIGHLIGHTS Chapters marked by an asterisk* have been entirely rewritten. Elements in blue italics have been extensively revised from the Third Edition.

S A M P L E P A G E S

7. Genetic Drift: Evolution at Random*l Drift in forward time and backward time (the coalescent)l Estimating effective population sizesl Codon bias and selection vs. driftl Inbreeding load versus inbreeding depressionl Examples of drift in human populations

l The evolution of species’ ranges; response to climate change

9. Species and Speciation*l Combines chapters on species and speciation from earlier editionsl Prezygotic isolation often evolves before postzygotic isolationl Speciation by genetic conflictl Speciation by random genetic driftl Parapatric speciation

10. All About Sex*l What are females and males?l The diversity and evolution of sex determination mechanismsl Operational sex ratio and sexual selectionl Alternative male mating strategiesl Sexual selection on flowering plantsl The evolution of recombination by selective interference and other factors

11. How To Be Fitl Evolution of ecological specialists and generalistsl Nonadaptive evolution of specialization

12. Conflict and Cooperation*l Green-beard evolution of cooperationl Selfishness can evolve by kin selectionl Eusociality can evolve in several waysl A worked example of an ESSl Evolution of spite

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DOUGLAS J. FUTUYMA and MARK KIRKPATRICK

S A M P L E P A G E S

To request an examination copy, visit our website: sinauer.com

l Selfish genes: transposons, segregation distortion, and cytonuclear conflictl Evolution of virulent and avirulent parasitesl Cooperation and major transitions in evolution

13. Interactions among Speciesl Red Queen coevolutionl Species diversity in ecological communities

14. The Evolution of Genes and Genomes*l The birth and death of genesl de novo genesl Gene traffickingl Alternative splicingl Evolution of chromosome numberl Adaptive and deleterious effects of transposable elementsl Evolution of genome size

15. Evolution and Developmentl Extensively revised, updated, and streamlinedl Comparative development and evolutionl Signaling molecules and morphological patternsl Evolution of cis- and trans-regulationl Evolution of phenotypic integrationl Phenotypic plasticity and adaptation

16. Phylogeny: Unity and Diversityl Why estimating phylogenies can be hardl Parsimony, maximum likelihood, and Bayesian methodsl Phylogenies based on phenotypesl Discovering the history of genes and culturesl Ancestral state reconstruction and functional studiesl The comparative method

l Phylogeny and classification

17. The History of Lifel Origin of eukaryotes from Archaeal Possible causes of the Cambrian explosionl Angiosperm diversification in early Cretaceous

18. The Geography of Evolutionl Explaining disjunct distributions by dispersal

DOUGLAS J. FUTUYMA and MARK KIRKPATRICK

l Explaining variable rates of evolution l Does speciation accelerate evolution?

21. The Evolutionary Story of Homo sapiensl How humans differ from other apesl The physical evolution of homininsl The evolution of brain and languagel Our genetic history (including hybridization)

To request an examination copy, visit our website: sinauer.com

NEW

19. The Evolution of Biological Diversityl Diversity-dependent vs. diversity- independent rates of diversification

20. Macroevolution: Evolution above the Species Levell Development and evolutionary enigmasl Biological homology and novel characters

l Agriculture: its pros and consl Genetic diversity and adaptation in human populationsl Evolutionary mismatches with modern environmentsl Natural selection on modern humansl Cultural evolution

22. Evolution and Societyl Answering evolutionary skepticsl Practical applications: using organisms’ adaptationsl Agriculture, pest management, conservation, health and medicinel Evolution and human behavior

Appendix: A Statistics Primerl Uses of statisticsl Probability distributionsl Descriptive statistics: means, variances, regressions, principle componentsl Estimationl Hypothesis testing: null hypotheses, significance, parametric tests, randomizationl Likelihoodl Bayesian inference

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A MAJOR REVISION, COMING IN MARCH

l A New Coauthor

l A New Organization

l A New Illustration Program

l Many New Topics (see inside)

Evolution, Fourth EditionDouglas J. Futuyma and Mark Kirkpatrick

SA MPLE PAGE From the

NEW Appendix