Calm Your Pet’s Soul

A happy pethas a “forever home.”

Pet owners are more likely

to consult free help options such as: the

internet, trainers, breeders, and

friends.5

Veterinarians lose up to 15% of

their client base each year due to unresolved

behavioral issues.6

Anxiety, fear, and stress play major roles in a majority of canine and feline behavioral disorders.2

Fear and anxiety disorders affect an estimated

23 million dogs in the U.S.3

DOG Fear and AnxietySigns

Trembling& Panting

OverGrooming

Elimination

EliminationOutside

Litterbox

Destruction

Spraying

Hiding & Escaping

Hiding

ExcessiveBarking

Inter-catAggression

Hyper-salivation

Panting

CAT Fear and AnxietySigns

In pet cats, behavior problemsare still the most common

cause of euthanasia.4

Up to 54% of pet owners

whose pets have behavioral issues have

NOT consulted a veterinarian.5

The #1 reason dogs are surrenderedto animal shelters is bad behavior.1

DIAGRAMS AREREPRESENTATIVE

L-theanine blocks excitatory glutamate receptors at the synapse while also stimulating the production of alpha brain waves throughout the brain.11,12

Whey protein concentrate supplements amino acid precursors required to synthesize serotonin and glutathione.13,16

Magnolia and Phellodendron extracts contain compounds which enhance the release of stabilizing GABA while blocking the release of glutamate at the synapse.9,10,14,15

Magnolia/Phellodendron

The combination of Magnolia and

Phellodendron extracts appear to be synergistic,

with the combination controlling stress and anxiety more effectively than either

compound used alone.14

Whey Protein Concentrate

Contains NMXSLQ05™ a

trademarked high quality protein source

which supplements essential amino acids including the precursors of glutathione

and serotonin.13,16

An amino acid found naturally in green

tea. It directly stimulates the production of alpha

brain waves, which create a state of deep relaxation, wakefulness, and mental

awareness.12

L-theanine

is for dogs and cats to help support normal behavior and facilitate a calming effect.

contains multiple active ingredients all in one chewable supplement.

is formulated to help facilitate contentment during periods of adjustment in a pet’s daily routine.

At the first sign of client complaint, veterinariansshould initiate management. Ask direct questions.

Are you having any trouble withdestructiveness or house soiling? 7

A COMPREHENSIVE APPROACH FOR BEHAVIORAL DISORDERS:

The specific cause of a pet’s anxiety may be difficult to isolate, and many anxiety issues occur in combination.8 The proper approach should be multi-modal.

Behavioral Modification/Conditioning

Avoidanceof Fear Anxiolytics

Alternative Modalities

Pharmaceuticals

NutritionalSupplement

Common causes of

anxiety

Traveling/Transportation

Loud Noises

Fireworks

Being Home Alone

Thunderstorms

Moving

Kenneling

Car Rides

Aging

Unfamiliar People

Unfamiliar Pets

Crating

New Smells

Environmental Changes

Multi-Cat Household

Enroll now in the Nutramax Laboratories Veterinary Sciences, Inc. Loyalty Program: nutramaxlabs.com/loyalty

SOLLIQUIN.COM

To learn more about Solliquin, contact your Nutramax Laboratories Veterinary Sciences, Inc. sales representative.Our customer service and technical advisors are available Monday thru Friday 8:30 am to 5:00 pm eastern time at 888-886-6442.

1. Miller DD, Staats SR, Partlo C, et al. Factors associated with the decision to surrender a pet to an animal shelter. Journal of the American Veterinary Medical Association 1996;209:738-742. 2. Landsberg GM, Hunthausen WL, Ackerman LJ. Fears, phobias, and anxiety disorders. Behavior Problems of the Dog and Cat. Edinburgh: Saunders/Elsevier, 2013;182-183. 3. Landsberg GM, Blizzard P, De Rivera C. Prevalence of fearful and anxious behaviors in dogs in the United States. STVV-ESVCE-ECAVBM 2012. 4. Practitioners AAoF. Feline Behavior Guidelines, 2004. 5. Shore ER, Burdsal C, Douglas DK. Pet owners’ views of pet behavior problems and willingness to consult experts for assistance. Journal of Applied Animal Welfare Science 2008;11:63-73. 6. Patronek GJ, Dodman NH. Attitudes, procedures, and delivery of behavior services by veterinarians in small animal practice. Journal of the American Veterinary Medical Association 1999;215:1606-1611. 7. Sherman BL. Separation anxiety in dogs. Compendium on Continuing Education for Practicing Veterinarian 2008; 30:27-42. 8. Overall KL, Dunham AE, Frank D. Frequency of nonspecific clinical signs in dogs with separation anxiety, thunderstorm phobia, and noise phobia, alone or in combination. Journal of the American Veterinary Medical Association 2001;219:467-473. 9. Patocka J, Jakl J, Strunecka A. Expectations of biologically active compounds of the genus Magnolia in biomedicine. Journal of Applied Biomedicine 2006;4:171-178.10. Alexeev M, Grosenbaugh DK, Mott DD, et al. The natural products magnolol and honokiol are positive allosteric modulators of both synaptic and extra-synaptic GABA(A) receptors. Neuropharmacology 2012;62:2507-2514.11. Nathan PJ, Lu K, Gray M, et al. The neuropharmacology of L-theanine(N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent. Journal of Herbal Pharmacotherapy 2006;6:21-30.12. Nobre AC, Rao A, Owen GN. L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pacific Journal of Clinical Nutrition 2008;17:167-168.13. Markus CR. Dietary amino acids and brain serotonin function; Implications for stress-related affective changes. Neuromolecular Medicine 2008;10:247-258.14. Li JM, Kong LD, Wang YM, et al. Behavioral and biochemical studies on chronic mild stress models in rats treated with a Chinese traditional prescription of banxia-houpu decoction. Life Sciences 2003;74:55-73.15. Lin T-Y, Lin T-Y, Lu C-W, et al. Berberine inhibits the release of glutamate in nerve terminals from rat cerebral cortex. PLoS ONE 2013;8:e67215.16. Yalcin AS. Emerging therapeutic potential of whey proteins and peptides. Current Pharmaceutical Design 2006;12:1637-1643.†DATA ON FILE.

“I encourage clients to administer a behavioral nutritional supplement for at least 4-6 weeks. While some benefits are apparent immediately,

the full effect may be more noticeable in the second month of continuous administration.” –Theresa L. DePorter, DVM, MRCVS, DECAWBM, DACVB

Relaxation without sedation † Intended for daily use Tasty chewables

03.1

063.

00

Under8 lbs

ForSmall Dogs

and Cats

60count

SoftChews

1 chewper day

Over30 lbs

ForMedium to Large Dogs

45count

ChewableTablets

31–45 lbs:½ tabletper day

46–90 lbs:1 tabletper day

8–30 lbs

ForSmall to Medium

Dogs andLarge Cats

75count

SoftChews

8–15 lbs:1 chewper day

16–30 lbs:2 chewsper day