A good looking pipeline

nacho caballero

slide makeover 3

BEfore

after

Read the accompanying

explanation

BEfore

P. acnes S. epidermidis

Core 88% 80%

Avg Size 2.5Mb 2.5Mb

GC 60% 32%

Average ORFs 2,626 2,436

# Sequenced Genomes 78 61

Comparative genome analyses

Conlan&et&al.,&Genome&Biology&2012,&Tomida&et&al.,&mBio&2013&

after 1

Conlan et al., Genome Biology 2012, Tomida et al., mBio 2013

Genomes highly conserved within a species

after 2

Conlan et al., Genome Biology 2012, Tomida et al., mBio 2013

Genomes highly conserved within a species

BEfore

after 1

after 2

Align reads !to strain

sequences

Reassign !ambiguous reads !with Pathoscope

Reassign !ambiguous reads !with Pathoscope

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