A decision tree valuation of a pharmaceutical company with...

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22 A decision tree valuation of a pharmaceutical company with one drug in the FDA pipeline… Aswath Damodaran 22 Test Abandon Succeed 70% Fail 30% -$50 -$140.91 Types 1 & 2 Type 2 Type 1 Fail 10% 10% 30% Develop Abandon Develop Abandon Develop Abandon Succeed Succeed Succeed Fail Fail Fail 75% 25% 80% 20% 80% 20% -$328.74 -$328.74 -$328.74 $585.62 -$328.74 -$97.43 -$366.30 -$366.30 $887.05 50% $50.36 $93.37 $573.71 -$143.69 $402.75

Transcript of A decision tree valuation of a pharmaceutical company with...

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AdecisiontreevaluationofapharmaceuticalcompanywithonedrugintheFDApipeline…

Aswath Damodaran

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Test

Abandon

Succeed

70%

Fail

30%-$50

-$140.91

Types 1 & 2

Type 2

Type 1

Fail

10%

10%

30%

Develop

Abandon

Develop

Abandon

Develop

Abandon

Succeed

Succeed

Succeed

Fail

Fail

Fail

75%

25%

80%

20%

80%

20%-$328.74

-$328.74

-$328.74

$585.62

-$328.74

-$97.43-$366.30

-$366.30

$887.05

50%

$50.36

$93.37

$573.71

-$143.69

$402.75

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KeyTestsforRealOptions

Aswath Damodaran

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¨ Isthereanoptionembeddedinthisasset/decision?¤ Canyouidentifytheunderlyingasset?¤ Canyouspecifythecontingencyunderwhichyouwillgetpayoff?

¨ Isthereexclusivity?¤ Ifyes,thereisoptionvalue.¤ Ifno,thereisnone.¤ Ifinbetween,youhavetoscalevalue.

¨ Canyouuseanoptionpricingmodeltovaluetherealoption?¤ Istheunderlyingassettraded?¤ Cantheoptionbeboughtandsold?¤ Isthecostofexercisingtheoptionknownandclear?

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I.OptionsinProjects/Investments/Acquisitions

Aswath Damodaran

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¨ Oneofthelimitationsoftraditionalinvestmentanalysisisthatitisstaticanddoesnotdoagoodjobofcapturingtheoptionsembeddedininvestment.¤ Thefirstoftheseoptionsistheoptiontodelaytakingainvestment,whenafirmhasexclusiverightstoit,untilalaterdate.

¤ Thesecondoftheseoptionsistakingoneinvestmentmayallowustotakeadvantageofotheropportunities(investments)inthefuture

¤ Thelastoptionthatisembeddedinprojectsistheoptiontoabandonainvestment,ifthecashflowsdonotmeasureup.

¨ Theseoptionsalladdvaluetoprojectsandmaymakea“bad” investment(fromtraditionalanalysis)intoagoodone.

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A.TheOptiontoDelay

Aswath Damodaran

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¨ Whenafirmhasexclusiverightstoaprojectorproductforaspecificperiod,itcandelaytakingthisprojectorproductuntilalaterdate.

¨ Atraditionalinvestmentanalysisjustanswersthequestionofwhethertheprojectisa“good” oneiftakentoday.

¨ Thus,thefactthataprojectdoesnotpassmustertoday(becauseitsNPVisnegative,oritsIRRislessthanitshurdlerate)doesnotmeanthattherightstothisprojectarenotvaluable.

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ValuingtheOptiontoDelayaProject

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Present Value of Expected Cash Flows on Product

PV of Cash Flows from Project

Initial Investment in Project

Project has negativeNPV in this section

Project's NPV turns positive in this section

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Example1:Valuingproductpatentsasoptions

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¨ Aproductpatentprovidesthefirmwiththerighttodeveloptheproductandmarketit.

¨ Itwilldosoonlyifthepresentvalueoftheexpectedcashflowsfromtheproductsalesexceedthecostofdevelopment.

¨ Ifthisdoesnotoccur,thefirmcanshelvethepatentandnotincuranyfurthercosts.

¨ IfIisthepresentvalueofthecostsofdevelopingtheproduct,andVisthepresentvalueoftheexpectedcashflowsfromdevelopment,thepayoffsfromowningaproductpatentcanbewrittenas:

Payofffromowningaproductpatent =V- I ifV>I=0 ifV≤I

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PayoffonProductOption

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Present Value ofcashflows on product

Net Payoff tointroduction

Cost of product introduction

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ObtainingInputsforPatentValuation

Input Estimation Process

1. Value of the Underlying Asset • Present Value of Cash Inflows from taking projectnow

• This will be noisy, but that adds value.2. Variance in value of underlying asset • Variance in cash flows of similar assets or firms

• Variance in present value from capital budgetingsimulation.

3. Exercise Price on Option • Option is exercised when investment is made.• Cost of making investment on the project ; assumed

to be constant in present value dollars.4. Expiration of the Option • Life of the patent

5. Dividend Yield • Cost of delay• Each year of delay translates into one less year of

value-creating cashflowsAnnual cost of delay = 1

n

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ValuingaProductPatent:Avonex

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¨ Biogen,abio-technologyfirm,hasapatentonAvonex,adrugtotreatmultiplesclerosis,forthenext17years,anditplanstoproduceandsellthedrugbyitself.

¨ Thekeyinputsonthedrugareasfollows:¤ PVofCashFlowsfromIntroducingtheDrugNow=S=$3.422billion¤ PVofCostofDevelopingDrugforCommercialUse=K=$2.875billion¤ PatentLife=t=17yearsRisklessRate=r=6.7%(17-yearT.Bond rate)¤ VarianceinExpectedPresentValues=s2 =0.224(Industryaveragefirmvariancefor

bio-techfirms)¤ ExpectedCostofDelay=y=1/17=5.89%

¨ Theoutputfromtheoptionpricingmodel¤ d1=1.1362 N(d1)=0.8720¤ d2=-0.8512 N(d2)=0.2076CallValue=3,422exp(-0.0589)(17)(0.8720)- 2,875exp(-0.067)(17) (0.2076)=$907million

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TheOptimalTimetoExercise

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17 16 15 14 13 12 11 10 9 8 7 6 5 4 3 2 1Number of years left on patent

Val

ue

Value of patent as option Net present value of patent

Exercise the option here: Convert patent to commercial product

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Valuingafirmwithpatents

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¨ Thevalueofafirmwithasubstantialnumberofpatentscanbederivedusingtheoptionpricingmodel.

ValueofFirm=Valueofcommercialproducts(usingDCFvalue+Valueofexistingpatents(usingoptionpricing)+(ValueofNewpatentsthatwillbeobtainedinthe

future– Costofobtainingthesepatents)¨ Thelastinputmeasurestheefficiencyofthefirmin

convertingitsR&Dintocommercialproducts.Ifweassumethatafirmearnsitscostofcapitalfromresearch,thistermwillbecomezero.

¨ Ifweusethisapproach,weshouldbecarefulnottodoublecountandallowforahighgrowthrateincashflows(intheDCFvaluation).

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ValueofBiogen’sexistingproducts

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¨ Biogenhadtwocommercialproducts(adrugtotreatHepatitisBandIntron)atthetimeofthisvaluationthatithadlicensedtootherpharmaceuticalfirms.

¨ Thelicensefeesontheseproductswereexpectedtogenerate$50millioninafter-taxcashflowseachyearforthenext12years.

¨ Tovaluethesecashflows,whichwereguaranteedcontractually,the pre-taxcostofdebtoftheguarantorswasused:PresentValueofLicenseFees=$50million(1– (1.07)-12)/.07

=$397.13million

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ValueofBiogen’sFutureR&D

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¨ Biogencontinuedtofundresearchintonewproducts,spendingabout$100milliononR&Dinthemostrecentyear.TheseR&Dexpenseswereexpectedtogrow20%ayearforthenext10years,and5%thereafter.

¨ Itwasassumedthateverydollarinvestedinresearchwouldcreate$1.25invalueinpatents(valuedusingtheoptionpricingmodeldescribedabove)forthenext10years,andbreakevenafterthat(i.e.,generate$1inpatentvalueforevery$1investedinR&D).

¨ Therewasasignificantamountofriskassociatedwiththiscomponentandthecostofcapitalwasestimatedtobe15%.

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ValueofFutureR&D

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Yr ValueofPatents R&DCost ExcessValue PV(at15%)

1 $150.00 $120.00 $30.00 $26.09

2 $180.00 $144.00 $36.00 $27.22

3 $216.00 $172.80 $43.20 $28.40

4 $259.20 $207.36 $51.84 $29.64

5 $311.04 $248.83 $62.21 $30.93

6 $373.25 $298.60 $74.65 $32.27

7 $447.90 $358.32 $89.58 $33.68

8 $537.48 $429.98 $107.50 $35.14

9 $644.97 $515.98 $128.99 $36.67

10 $773.97 $619.17 $154.79 $38.26

$318.30

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ValueofBiogen

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¨ ThevalueofBiogenasafirmisthesumofallthreecomponents– thepresentvalueofcashflowsfromexistingproducts,thevalueofAvonex(asanoption)andthevaluecreatedbynewresearch:Value=Existingproducts+ExistingPatents+Value:FutureR&D

=$397.13million+$907million+$318.30million=$1622.43million

¨ SinceBiogenhadnodebtoutstanding,thisvaluewasdividedbythenumberofsharesoutstanding(35.50million)toarriveatavaluepershare:¤Valuepershare=$1,622.43million/35.5=$45.70

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TheRealOptionsTest:PatentsandTechnology

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¨ TheOptionTest:¤ UnderlyingAsset:Productthatwouldbegeneratedbythepatent¤ Contingency:

n IfPVofCFsfromdevelopment>Costofdevelopment:PV- Costn IfPVofCFsfromdevelopment<Costofdevelopment:0

¨ TheExclusivityTest:¤ Patentsrestrictcompetitorsfromdevelopingsimilarproducts¤ Patentsdonotrestrictcompetitorsfromdevelopingotherproductstotreatthesamedisease.

¨ ThePricingTest¤ UnderlyingAsset:Patentsarenottraded.Notonlydoyouthereforehavetoestimatethepresentvaluesand

volatilitiesyourself,youcannotconstructreplicatingpositionsordoarbitrage.¤ Option:Patentsareboughtandsold,thoughnotasfrequentlyasoilreservesormines.¤ CostofExercisingtheOption:Thisisthecostofconvertingthepatentforcommercialproduction.Here,

experiencedoeshelpanddrugfirmscanmakefairlypreciseestimatesofthecost.

¨ Conclusion:Youcanestimatethevalueoftherealoptionbutthequalityofyourestimatewillbeadirectfunctionofthequalityofyourcapitalbudgeting.Itworksbestifyouarevaluingapubliclytradedfirmthatgeneratesmostofitsvaluefromoneorafewpatents- youcanusethemarketvalueofthefirmandthevarianceinthatvaluetheninyouroptionpricingmodel.

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Example2:ValuingNaturalResourceOptions

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¨ Inanaturalresourceinvestment,theunderlyingassetistheresourceandthevalueoftheassetisbasedupontwovariables- thequantityoftheresourcethatisavailableintheinvestmentandthepriceoftheresource.

¨ Inmostsuchinvestments,thereisacostassociatedwithdevelopingtheresource,andthedifferencebetweenthevalueoftheassetextractedandthecostofthedevelopmentistheprofittotheowneroftheresource.

¨ DefiningthecostofdevelopmentasX,andtheestimatedvalueoftheresourceasV,thepotentialpayoffsonanaturalresourceoptioncanbewrittenasfollows:

Payoffonnaturalresourceinvestment =V- X ifV>X=0 ifV≤X

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PayoffDiagramonNaturalResourceFirms

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Value of estimated reserve of natural resource

Net Payoff onExtraction

Cost of Developing Reserve

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EstimatingInputsforNaturalResourceOptions

Input Estimation Process

1. Value of Available Reserves of the Resource • Expert estimates (Geologists for oil..); Thepresent value of the after-tax cash flows fromthe resource are then estimated.

2. Cost of Developing Reserve (Str ike Price) • Past costs and the specifics of the investment

3. Time to Expiration • Relinqushment Period: if asset has to berelinquished at a point in time.

• Time to exhaust inventory - based uponinventory and capacity output.

4. Variance in value of underlying asset • based upon variability of the price of theresources and variability of available reserves.

5. Net Production Revenue (Dividend Yield) • Net production revenue every year as percentof market value.

6. Development Lag • Calculate present value of reserve based uponthe lag.

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ValuingGulfOil

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¨ GulfOilwasthetargetofatakeoverinearly1984at$70pershare(Ithad165.30millionsharesoutstanding,andtotaldebtof$9.9billion).¤ Ithadestimatedreservesof3038millionbarrelsofoilandtheaveragecostofdevelopingthesereserveswasestimatedtobe$10abarrelinpresentvaluedollars(Thedevelopmentlagisapproximatelytwoyears).

¤ Theaveragerelinquishmentlifeofthereservesis12years.¤ Thepriceofoilwas$22.38perbarrel,andtheproductioncost,taxesandroyaltieswereestimatedat$7perbarrel.

¤ Thebondrateatthetimeoftheanalysiswas9.00%.¤ Gulfwasexpectedtohavenetproductionrevenueseachyearofapproximately5%ofthevalueofthedevelopedreserves.Thevarianceinoilpricesis0.03.

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ValuingUndevelopedReserves

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¨ Inputsforvaluingundevelopedreserves¤ Valueofunderlyingasset=Valueofestimatedreservesdiscountedbackforperiod

ofdevelopmentlag=3038*($22.38- $7)/1.052 =$42,380.44¤ Exerciseprice=Estimateddevelopmentcostofreserves=3038*$10=$30,380

million¤ Timetoexpiration=Averagelengthofrelinquishmentoption=12years¤ Varianceinvalueofasset=Varianceinoilprices=0.03¤ Risklessinterestrate=9%¤ Dividendyield=Netproductionrevenue/Valueofdevelopedreserves=5%

¨ Basedupontheseinputs,theBlack-Scholesmodelprovidesthefollowingvalueforthecall:d1=1.6548 N(d1)=0.9510d2=1.0548 N(d2)=0.8542CallValue=42,380.44exp(-0.05)(12)(0.9510)-30,380(exp(-0.09)(12) (0.8542)

=$13,306million

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ValuingGulfOil

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¨ Inaddition,GulfOilhadfreecashflows tothefirmfromitsoilandgasproductionof$915millionfromalreadydevelopedreservesandthesecashflows arelikelytocontinuefortenyears(theremaininglifetimeofdevelopedreserves).

¨ Thepresentvalueofthesedevelopedreserves,discountedattheweightedaveragecostofcapitalof12.5%,yields:¤ Valueofalreadydevelopedreserves=915(1- 1.125-10)/.125=$5065.83

¨ AddingthevalueofthedevelopedandundevelopedreservesValueofundevelopedreserves =$13,306millionValueofproductioninplace =$5,066millionTotalvalueoffirm =$18,372millionLessOutstandingDebt =$9,900millionValueofEquity =$8,472millionValuepershare =$8,472/165.3 =$51.25