A case study on Mastitis

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    Welcome You AllClinical Conference II

    Presented by:

    Group I

    Roll No: 01,02,33 &34

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    A Case Study on Mastitis

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    Owners Name: OM Bahadur Gurung

    Address: Rampur-2, Mangalpur

    Date: 25th Bhadra, 2070

    Species: Bovine

    Breed: Murrah Cross

    Sex: Female

    Age: 3.5 years

    Lactation: 1st lactation

    Case HistoryAnorexia

    Decreased Milk Secretion from LH

    Quarter

    Milk watery in appearance from

    affected quarter

    Swollen and Redden udder

    Parturated 20 days ago

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    Clinical ExaminationTemperature: 105 F (99-102)

    Pulse: 49/min (42-60)

    Respiration: 20/min (16-22)

    Udder Examination revealed

    swollen, painful Fibrotic mass

    Clinical FindingsFever (105 F)

    Udder Swollen, reddish,firm

    Incomplete milk let down

    Slightly Anorexia

    Milk watery in consistency

    Tentative Diagnosis: Mastitis 4

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    Microbiological and Bio chemical Test

    Pink colony on Mac Conkey Pale colony on Nutrient Agar

    CMT Negative

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    Differential DiagnosisDiseases Features

    Udder oedema No Abnormal Milk

    Response to Diuretic Therapy

    Udder Tuberculosis No pain or hotness

    Positive Z-N staining

    Actinomycosis of Udder Pus (sulfur granules)in udder

    Hard nodules in udder

    Rupture of Suspensory Ligament History of injury,

    No abnormal milk

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    Result of Antibiotic Sensitivity Test

    Antibiotics Result

    Gentamicin Resistant

    Ciprofloxacin Resistant

    Amikacin Resistant

    Tetracycline Resistant

    Cephalosporin Sensitive

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    Confirmatory Diagnosis

    Coliform Mastitis

    Clinician: Dr. S.B. Raut, VTH

    Treatment

    1. X-ceft

    Sig: 1gm IM 3 days2. Inj. E-Care-Se

    Sig: 10 ml IM alternate days 3 inj.

    Advice:Tip dipping with Povidone Iodine

    bid

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    Discussion

    Mastitis is the inflammation of parenchyma ofmammarygland

    characterized by range of physical and chemical changes inmilk and pathological changes in glandular tissues (Radostitis et

    al., 2009).

    Etiology

    Contagious pathogens: Staphylococcus aureus, Streptococcus

    agalactiae

    Environmental Pathogens: Coliforms include E.coli, Klebsiella,

    Enterobacter spp.

    Opportunistic pathogens: Coagulase negative staphylococci

    Uncommon Pathogens: Mycobacterium bovis,Fungi and Yeasts.

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    Epidemiology

    Environmental pathogens are from environment and induce

    mastitis between milking.

    Contagious pathogens are transmitted at time of milking.

    Risk Factors

    Animal risk factors: Prevalence of infection increases with

    age. Most new infections occur in dry period and in early

    lactation. High producing cows are more susceptible.

    Environmental risk factors: Poor quality management of

    housing and bedding increases infection rate.

    Pathogen risk factors: virulence factors, susceptibilty to anti

    microbial agents

    Economics: Loss of milk production, costs of treatment and

    early culling

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    Prevalence of Mastitis in Buffaloes

    Prevalence Author Region

    37.5% Dhakal & Tiwari, 1993 IAAS Farm

    38.09% Dhakal & Tiwari, 1993 Mangalpur VDC

    44% Subedi & Dhakal,2002 Chitwan

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    Pathogenesis

    Invasion phase

    Entry of Pathogen into Teat Canal

    Invasion of mammary Tissue and Stabilisation in Teat Canal

    Infection Stage (multiplication and extension into mammary tissues)

    {Production of Endotoxin

    e.g. E.Coli

    Development of SystemicRXN

    Exotoxin and Cellular components

    Chemotaxis of Leucocytes to

    inflammatory cells

    Inflammation stage

    Damage to mammary tissue

    Swelling and increased temperature in

    acute cases12

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    Control & Prophylaxis

    Dry Cow Therapy: Vet-o-Max Long acting ointment 1 tube Intrammary eachquarter SD

    Antiseptic Washing: 5% chlorhexidine solution

    Kohrosolin TH 1.5%

    Post Dipping BID

    Milking Hygiene: Positive animal should be milked last.

    Milker should wash their hand with detergent.

    Do not allow animal to sit for 30 minutes after milking.

    VaccinationMASTIVACSig: 5 ml IM 1 wk interval 3 injection prior to parturition

    5 ml IM 3 days interval 2 injection

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    References:

    Laha, R., M. Das, A. Goswami and P. Singh. 2012. Indian Journal

    of Animal Research, 46(3):302-305

    Radostitis, O.M., C.C. Gay, D.C. Blood and K.W. Hinchcliff. 2000.

    Veterinary Medicine A Textbook of the Diseases of Cattle,

    Sheep, Pigs, Goats and Horses,9th ed. W.B.Saunders. 1289pThe Merck Veterinary Manual, 2012. Canine Parvovirus

    http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc

    23301.htm. (Assessed on 15th September. 2013).

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