7th INTERNATIONAL HYPOTHERMIA & TEMPERATURE

MANAGEMENT SYMPOSIUMAugust 28 - 30, 2018

WWW.IHTMS.ORG

Proudly supported by:

@IHTMSymposium #IHTMS18

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Approved for CPD points by the College of Intensive Care Medicine (Lectures – Category 2A, points per hour 1)

SOCIAL FUNCTIONS NB. These are ticketed events

Networking Drinks Date: Tuesday 28th August Time: 6pm - 7:30pm Venue: Wild Life Sydney Zoo, Darling Harbour Dress Code: Smart Casual 6pm - 6:30pm - Animal Viewing 6:30pm - 7:30pm - Drinks & Nibbles No entry after 6:30pm

Symposium DinnerDate: Thursday 30th AugustTime: 7pm - 10pmVenue: Blue Room Glass BoatDress Code: Smart CasualBoard: 7pm, King Street WharfDeparts: 7:15pm (strict departure time) Returns: 10pm Proudly supported by:

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1400 Welcome Address Manoj SaxenaAustralia Naomi Hammond Australia

PLENARY ONE - Hypothermia for Neonatal Birth AsphyxiaSession Chair: John Beca & Manoj Saxena1410 The Preclinical Foundations of Therapeutic Hypothermia Alistair Gunn

New Zealand1445 Discussion Time

1455 Therapeutic Hypothermia improves outcomes for Neonatal Birth Asphyxia

Alistair Gunn New Zealand

1530 Discussion Time

1540 Afternoon Tea

IHTMS 2018 - DAY ONETuesday 28th August 2018

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NETWORKING DRINKS - Wild Life Sydney Zoo, Darling Harbour 1800 - 1930 Tuesday 28th August (see page 1 for more information)

LECTURE SESSION ONE - Basic Science / TranslationSession Chairs: Dalton Dietrich & John Myburgh1610 Systematic Review of Animal Models of Cardiac Arrest Hans Friberg

Sweden

1630 Systematic Review of Animal Models of Traumatic Brain Injury

Peter Andrews United Kingdom

1650 Panel Discussion - Why the difference between Neonatal birth asphyxia and adult / paediatric brain injury?

All speakers from session

1720 Closing Remarks Andrew Cheng Australia

1730 End of Meeting - Day One

1800 - 1930 Networking Drinks

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PLENARY TWOSession Chairs: Manoj Saxena & Celia Bradford0800 Hypothermia for Traumatic Intracranial Hypertension –

The future after EUROTHERMPeter Andrews United Kingdom

PLENARY THREESession Chairs: Manoj Saxena & Celia Bradford0830 Measuring Outcomes After Brain Injury:

Neurocognitive functionGisela Lilja Sweden

0850 Measuring Outcomes After Brain Injury: Physical function

Carol HodgsonAustralia

0910 PANEL DISCUSSION ONE: Outcomes – What really matters?Session Chairs: Manoj Saxena & Celia BradfordRecovering From Cardiac Arrest and Traumatic Brain Injury: How best to measure outcome?1000 Morning Tea

IHTMS 2018 - DAY TWOWednesday 29th August 2018

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LECTURE SESSION TWO - Multimodal Monitoring for Brain Injury: International perspectivesSession Chairs: Andrew Udy & Andrew Cheng1030 Beyond ICP and CPP: Brain metabolism under fever

and TTMRaimund HelbokAustria

1045 Continuous EEG for Monitoring after Cardiac Arrest Tobias Cronberg Sweden

1100 Induced Cooling and Brain Tissue Oxygenation Jonathon Rhodes United Kingdom

1115 The Effect of Oxygen, Carbon Dioxide and MAP on Brain Oxygenation in Cardiac Arrest Patients Undergoing TTM

Markus Skrifvars Finland

1130 Cerebrovascular Autoregulation During Cooling Anders Aneman Australia

1145 Post-resuscitation Brain Monitoring with Targeted Temperature Management

Xiaofeng Jia United States of America

1200 TTM Stratified by rSO2 Kei Nishiyama Japan

1215 Panel Discussion All speakers from session

1230 Lunch

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PLENARY FOURSession Chairs: Jamie Cooper & Anders Aneman1330 Brain Temperature and Concussion Dalton Dietrich

United States of America

THE HAYASHI PRIZE - Oral Abstract PresentationsSession Chairs: Hans Friberg & Ken Nagao 1415 Hypothermia reduces and hyperthermia augments

T cell-derived release of perforin that mediates the death of brain endothelial cells and neuronal cells

Tomohiro MatsuiJapan

1425 Animal studies on traumatic brain injury and hypothermia may be of low quality and with risk of bias

Max Klasén Sweden

1435 Increased heart rate response during the rewarming phase of therapeutic hypothermia is associated with favorable neurological outcomes in out-of-hospital cardiac arrest patients

Akihiko InoueJapan

Continued over page...

Wednesday 29th August 2018IHTMS 2018 - DAY TWO#IHTMS18

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From previous page...

1445 Targeted temperature management for subarachnoid hemorrhage: Neurocritical care ameliorates neurologic outcome

Yasuhiro KurodaJapan

1455 Targeted temperature management: How close are we to achieving the revised target temperature after Cardiac Arrest?

David BowenUnited Kingdom

1505 A before-after study of variability in temperature control at a target of 36°C versus 33°C for targeted temperature management post cardiac arrest

Renesh NairNew Zealand

1515 Afternoon Tea

Wednesday 29th August 2018IHTMS 2018 - DAY TWO

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LECTURE SESSION THREE - Extra Corporeal Membrane Oxygenation + TTM:International perspectivesSession Chairs: David Gaeski & Danielle Austin1545 Treatment Starts When the Call Comes In: The

case for IH/ECMO in pre-hospital careMarc ConteratoUnited States of America

1605 The CHEER Study Andrew UdyAustralia

1625 The SAVE-J Study: Prospective National Registry: E-CPR vs standard care

Tetsuya SakomotoJapan

1645 Neurological Prognostic Indicators and Current Status of Extracorporeal CPR for Cardiac Arrest Patients

Noritoshi ItoJapan

1705 Panel Discussion All speakers from session1730 End of Meeting - Day Two

Wednesday 29th August 2018IHTMS 2018 - DAY TWO

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IHTMS 2018 - DAY THREEThursday 30th August 2018

LECTURE SESSION FOUR - The Practical Implementation of TTMSession Chairs: Naomi Hammond & Paul Young0800 Pharmacology and Induced Cooling: A two way

streetGretchen BrophyUnited States of America

0820 No Longer Science Fiction: Cooling the conscious patient

Jon RittenbergerUnited States of America

0840 Cooling: A practical approach for the unconscious patient

Kelly HarbourAustralia

0855 Induction, Maintenance and Re-warming Jon RittenbergerUnited States of America

0910 Does the Method of Cooling Matter? Markus SkrifvarsFinland

0925 Panel Discussion All speakers from session

0945 Morning Tea

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Thursday 30th August 2018IHTMS 2018 - DAY THREE

LECTURE SESSION FIVE - Novel ConceptsSession Chairs: Andrew Cheng & Markus Skrifvars1015 Novel Modalities of Cooling: Pharmacology and

hibernationFred RinconUnited States of America

1025 Novel Biomarkers of Neurological Injury Hans FribergSweden

1035 Blood Cooling Using KTEK Takahiro MikiJapan

1045 Hypothermia for Subdural Haemorrhage Hitoshi KobataJapan

1055 Panel Discussion All speakers from session

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LECTURE SESSION SIX - Fever ControlSession Chairs: Paul Young & Frédérique Schortgen1115 Fever Prevention in Acute Vascular Brain Injury:

Update on the INTREPID studyDavid GreerUnited States of America

1125 Pyrexia Prevention for TBI Manoj SaxenaAustralia

1135 Brain Temperature: The real target for TTM Raimund HelbokAustria

1145 Panel Discussion All speakers from session

1200 Lunch

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CLINICAL TRIALS ONE Session Chair: Raimund Helbok & Hans Kirkegaard1300 Paracetamol for Infections Paul Young

New Zealand

1310 Normothermia for Septic Shock Frédérique Schortgen France

1320 Hypothermia for Septic Shock Morten Bestle Denmark

1330 Hypothermia for Meningitis Frédérique Schortgen France

1340 Panel Discussion All speakers from session

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CLINICAL TRIALS TWO Session Chair: Gene Sung & Morten Bestle1400 Hypothermia for Paediatric Cardiac Arrest John Beca

New Zealand

1410 Hypothermia for Adult Cardiac Arrest (24 vs 48 hours)

Hans Kirkegaard Denmark

1420 J-Pulse-Hypo: Registry, two temperature targets Hiroshi Nonogi Japan

1430 Rationale + Update for the TTM2 Study Hans Friberg Sweden

1440 Panel Discussion All speakers from session

1500 Afternoon Tea

Thursday 30th August 2018IHTMS 2018 - DAY THREE

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1530 PANEL DISCUSSION TWOSession Chair: Celia Bradford & Simon FinferFrom Evidence to Guidelines and the Patient in Front of Me: Making sense of it all and where to from here?1630 Meeting Close / Hayashi Prize Award

1645 End of Meeting

1900 - 2200 7th International Hypothermia & Temperature Management Symposium Dinner

Thursday 30th August 2018IHTMS 2018 - DAY THREE

7th INTERNATIONAL HYPOTHERMIA & TEMPERATURE MANAGEMENT SYMPOSIUM DINNER - Blue Room Glass Boat

1900 - 2200 Thursday 30th August (see page 1 for more information)

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Proudly supported by:

The 7th IHTMS gratefully acknowledges the support of our meeting sponsors:

GOLD SPONSOR SILVER SPONSORS

BRONZE SPONSORS

PLATINUM SPONSOR

We also thank BD BARD for their provision of a fixed unrestricted educational grant.