7 Ways to Prevent and Even Reverse Heart Disease With Nutrition

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    7 Ways To Prevent and Even Reverse Heart Disease

    With NutritionPosted on:

    Monday, April 22nd 2013 at 2:00 pmWritten By:

    Sayer Ji, Founder

    Considering that heart disease is the #1 cause o death in the de!eloped "orld, anything that can pre!ent cardiac

    mortality, or slo" or e!en re!erse the cardio!ascular disease process, should e o great interest to the general pu

    %adly, millions o ol&s are una"are o the e'tensi!e ody o iomedical literature that e'ists supporting the use onatural compounds or pre!enting and e!en re!ersing heart disease$

    (nstead, they spend illions uying highly to'ic cholesterol)lo"ering pharmaceuticals "ith known cardiotoxicity,

    among!! other "roven side e##ects, simply ecause their doctor told them to do so$

    %o, "ith this in mind, let*s loo& at the iomedical literature itsel$

    Three Natura$ Su%stances that Reduce the Risk o# Heart&Re$ated Death

    '(e)a& Fatty *cids: +here is a roust ody o research indicating that the ris& o sudden cardiac death is reduce"hen consuming higher le!els o omega)3 atty acids$ oing all the "ay ac& to 2002, theNew England Journal oMedicinepulished a study titled, -Blood le!els o long)chain n)3 atty acids and the ris& o sudden death,- "hich

    ound -+he n)3 atty acids ound in ish are strongly associated "ith a reduced ris& o sudden death among men

    "ithout e!idence o prior cardio!ascular disease$- Another 2002 study, pulished in the .ournal Circulation, oundthat /mega)3 atty acid supplementation reduces total mortality and sudden death in patients "ho ha!e already had

    heart attac&$ior additional research, !ie" our dataset on the topic o '(e)a& #atty acids and the reduction ocardiac (orta$ity$

    (t should e noted that the est)selling cholesterol drug class &no"n as statins may actually reduce the e##ectivene

    o# o(e)a& #atsat protecting the heart$ +his has een oered as an e'planation as to "hy ne"er research seems to

    sho" that consuming omega)3 ats does not lo"er the ris& o cardiac mortality$

    +ita(in D: e!els o this essential compound ha!e een ound to e directly associated "ith the ris& o dying rom

    all causes$ Being in the lo"est 245 percent o !itamin 6 le!els is associated "ith a 275 increased rate o all)causemortality$ii (t has een proposed that douling gloal !itamin 6 le!els could signiicantly reduce mortality$iii

    8esearch pulished in the .ournal Clinical Endocrinology in 2009 conirmed that lo"er !itamin 6 le!els are

    Object1

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    associated "ith increased all)cause mortality ut also that the eect is e!en more pronounced "ith cardio!ascular

    mortality$i!+his inding "as conirmed the same year in the ournal o the American eriatric %ociety,!and

    again in 2010 in the American ournal o Clinical ;utrition$!i

    a)nesiu(: (n a "orld gone mad o!er ta&ing inorganic calcium supplementation #or invented diseases such as T

    score de#ined -osteo"enia- or -osteo"orosis,-despite their "ell)&no"n association "ithincreased risk o#

    cardiac (orta$ity, magnesium*s role in protecting against heart disease cannot e o!erstressed$ (t is "ell)&no"n th

    e!en the accelerated aging o the heart muscle e'perienced y those in long s"ace #$i)ht is due to (a)nesiu(

    de#iciency$ (n 2010, theJournal of Biomedical Sciencesreported that cardio!ascular ris&s are signiicantly lo"er i

    indi!iduals "ho e'crete higher le!els o magneiusm, indicating its protecti!e role$!ii Another study pulished in

    the .ournalAtherosclerosisin 2011 ound that lo" serum magnesium concentrations predict cardio!ascular and allcause mortality$!iii8ememer that "hen you are loo&ing to *supplement* your diet "ith magnesium go green$

    Chlorophyll is green ecause it has a magnesium atom at its center$.a$e,or e'ample, is ar etter a source o

    comple' nutrition than magnesium supplements$ But, ailing the culinary approach, magnesium supplements can highly eecti!e at attaining a therapeutic and reducing inlammation$ '

    *r)inine: Preclinical and clinical research indicates that this amino acid not only pre!ents the progression oatherosclerosis ut also re!erses pathologies associated "ith the process$ =see also:/$o))ed *rteries and *r)inin/ne o the mechanisms in "hich it accomplishes this eat is y increasing the production o nitric o'ide "hich is

    normally depressed in lood !essels "here the inner lining has een damaged =endothelium> resulting in dysuncti

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    1ar$ic: ;ot only has garlic een ound to reduce a multitude o ris& actors associated "ith arteriosclerosis, the

    thic&ening and hardening o the arteries, ut it also signiicantly reduces the ris& o heart attac& and stro&e$'i (n

    !itro research has conirmed that garlic inhiits arteriosclerotic pla?ue ormation$'ii Aged garlic e'tract has alsoeen studied to inhiit the progression o coronary artery calciication in patients recei!ing statin therapy$'iii

    And let us not orget, garlic*s eneits are e'tremely road$ We ha!e identiied o!er 140 diseases that this remar&a

    culinary and medicinal her has een conirmed to e o potential !alue in treating and pre!enting and "hich can

    !ie"ed here:1ar$ic Hea$th 2ene#its$

    2&/o("$ex: /ne o the e" !itamin categories that has een conirmed in human studies to not only reduce the

    progression o pla?ue uildup in the arteries ut actually re!erse it is B)comple'$ A 2009 study pulished in the.ournal Strokeound that high dose B)comple' !itamin supplementation signiicantly reduces the progression o

    early)stage suclinical atherosclerosis in healthy indi!iduals$'i!More remar&aly, a 2004 study pulished in the.ournalAtherosclerosisound a B)!itamin ormula decreased the carotid artery thic&ness in patients at ris& or

    cereral ischemia$'!Another possile e'planation or these positi!e eects is the role B)!itamins ha!e in reducin

    the production o homocysteine, an artery and other"ise lood !essel scarring amino acid$'!i

    7 Ways To Prevent and Even Reverse Heart Disease

    With Nutrition & Pa)e 3Posted on:Monday, April 22nd 2013

    Sayer Ji, Founder

    or additional research on artery unclogging sustances !isit our page dedicated to the topic 0nc$o))in) *rteries

    *dditiona$ Heart 0n#riend$y Thin)s To *void

    ;o discussion o pre!enting cardiac mortality "ould e complete "ithout discussing things that need to e remo!e

    in order to reduce ris&, such as:

    NS*5Ds: 6rugs li&eas"irin, iuproen, and +ylenol, ha!e "ell)&no"n association "ith increased cardiac mortalit8e!ie" si' studies on the topic here:NS*5D /ardiotoxicity$

    Statin Dru)s: (t is the height o irony that the !ery category o drugs promoted to millions gloally as the standard

    o care or primary and secondary pre!ention o cardio!ascular disease and cardiac mortality are actually cardioto'

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    agents, lin&ed to no less than 300 ad!erse health eects$ %tatin drugs ha!e de!astating health eects$ 'plore the

    research here: Statin Dru) Hea$th E##ects$

    Wheat: "hile this connection is rarely discussed, e!en y those "ho promote grain)ree and "heat ree diets, "he

    has proound cardioto'ic potential, along "ith o!er 200 documented ad!erse health eects:Wheat Toxicity$ And"hy "ouldn*t it, "hen the !ery countries that eat the most o it ha!e the highest rate o cardio!ascular disease and

    heart)related deaths or an in)depth e'planation read our article:Wheat6s /ardiotoxicity *s Serious *s * Hear*ttack4

    inally, or additional research on the topic o heart health promoting strategies !isit our ealth uide: Heart

    Hea$th$

    Re#erences

    i 8oerto Marchioli, ederica BarDi, lena Boma, Carmine Chieo, 6omenico 6i regorio, 8occo 6i

    Mascio, Maria raDia ranDosi, nrico eraci, iacomo e!antesi, Aldo Pietro Maggioni, oredana Manti8osa Maria Marisi, Mastrogiuseppe, ;icola Mininni, ian uigi ;icolosi, Massimo %antini, Carlo

    %ch"eiger, uigi +a!aDDi, ianni +ognoni, Corrado +ucci, ranco Ealagussa,$Ear$y "rotection a)ainstsudden death %y n& "o$yunsaturated #atty acids a#ter (yocardia$ in#arction ti(e&course ana$ysis o#

    the resu$ts o# the 1ru""o 5ta$iano "er $o Studio de$$a So"ravviven8a ne$$65n#arto iocardico 915SS5:&

    Preven8ione4Circulation$ 2002 Apr 23F104=17>:1G9H)903$ PM(6:1199H2H@

    ii Michal Melamed, rin 6 Michos, Wendy Post, Brad Astor$ 3;&hydroxyvita(in D $eve$s and the risko# (orta$ity in the )enera$ "o"u$ation4Arch (ntern Med$ 200G Aug 11F17G=14>:1729)3H$ PM(6: 1G7940H

    iii W B rant$ *n esti(ate o# the )$o%a$ reduction in (orta$ity rates throu)h dou%$in) vita(in D

    $eve$s4ur Clin ;utr$ 2011 ul 7$ pu 2011 ul 7$ PM(6: 21H31037

    i! %tean PilD, arald 6onig, iel ;i.pels, 8oert eine, Coen 6 A %tehou"er, Marie&e B %ni.der, 8o

    M !an 6am, ac?ueline M 6e&&er$+ita(in D and (orta$ity in o$der (en and wo(en4Clin ndocrinol=/'>$ 2009 ;o!FH1=4>:777)H2$ pu 2009 e 1G$ PM(6: 192272H2

    ! Adit A inde, 8oert %cragg, 8oert % %ch"artD, Carlos A Camargo$ Pros"ective study o# seru( 3;&

    hydroxyvita(in D $eve$, cardiovascu$ar disease (orta$ity, and a$$&cause (orta$ity in o$der 04S4 adu$ts

    Am eriatr %oc$ 2009 %epF4H=9>:1494)703$ pu 2009 un 22$ PM(6: 194@9021 !i Iarl MichaJlsson, ohn A Baron, reta %nellman, 8ol edeorg, iisa Byerg, ohan %undstrKm, ar

    Berglund, ohan ArnlK!, Per ellman, 8une Blomho, Alic.a Wol&, ans armo, ars olmerg, L&an

    Melhus$ P$as(a vita(in D and (orta$ity in o$der (en a co((unity&%ased "ros"ective cohort study4Am Clin ;utr$ 2010 /ctF92=@>:G@1)G$ pu 2010 Aug 1G$ PM(6: 20H20247

    !ii u&io amori, +a&ashi +aguchi, ide&i Mori, Mari Mori$ WH'&/*RD5*/

    study "o"u$ations in the wor$d4 Biomed %ci$ 2010F1H %uppl 1:%21$ pu 2010 Aug 2@$ PM(6: 20G0@49

    !iii +horsten 8eelmann, +ill (ttermann, Marcus 6Krr, enry EKlD&e, Mar&us 8einthaler, AstridPetersmann, %tephan B eli'$:21H)2@$ PM(6: 10@G37G@

    'ii Nnter %iegel, ran& Michel, Michael Ploch, Miguel 8odrOgueD, Martin Malmsten$ ?5nhi%ition o#

    arteriosc$erotic "$aAue deve$o"(ent %y )ar$ic@4Wien Med Wochenschr$ 200@ ;o!F14@=21)22>:414)22$

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-magnesium-concentrations-predict-cardiovascular-and-all-cause-mortalityhttp://www.greenmedinfo.com/article/low-serum-magnesium-concentrations-predict-cardiovascular-and-all-cause-mortalityhttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref9http://www.greenmedinfo.com/blog/can-pomegranate-keep-you-going-under-knifehttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref10http://www.greenmedinfo.com/substance/pomegranatehttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref11http://www.greenmedinfo.com/article/garlic-reduces-multitude-risk-factors-associated-arteriosclerosis-and-significantly-reduceshttp://www.greenmedinfo.com/article/garlic-reduces-multitude-risk-factors-associated-arteriosclerosis-and-significantly-reduceshttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref12http://www.greenmedinfo.com/article/garlic-inhibits-arteriosclerotic-plaque-formation-vitrohttp://www.greenmedinfo.com/article/garlic-inhibits-arteriosclerotic-plaque-formation-vitrohttp://www.greenmedinfo.com/guide/health-guide-statin-drugshttp://www.greenmedinfo.com/toxic-ingredient/wheathttp://www.greenmedinfo.com/blog/wheats-cardiotoxicity-serious-heart-attackhttp://www.greenmedinfo.com/blog/wheats-cardiotoxicity-serious-heart-attackhttp://www.greenmedinfo.com/guide/health-guide-heart-healthhttp://www.greenmedinfo.com/guide/health-guide-heart-healthhttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref1http://www.greenmedinfo.com/article/omega-3-fatty-acid-supplementation-reduces-total-mortality-and-sudden-death-patients-whohttp://www.greenmedinfo.com/article/omega-3-fatty-acid-supplementation-reduces-total-mortality-and-sudden-death-patients-whohttp://www.greenmedinfo.com/article/omega-3-fatty-acid-supplementation-reduces-total-mortality-and-sudden-death-patients-whohttp://www.greenmedinfo.com/article/omega-3-fatty-acid-supplementation-reduces-total-mortality-and-sudden-death-patients-whohttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref2http://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref3http://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref4http://www.greenmedinfo.com/article/lower-vitamin-d-levels-are-associated-all-cause-mortality-and-even-more-pronouncedhttp://www.greenmedinfo.com/article/lower-vitamin-d-levels-are-associated-all-cause-mortality-and-even-more-pronouncedhttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref5http://www.greenmedinfo.com/article/serum-vitamin-d-levels-have-independent-inverse-association-cardiovascular-disease-and-allhttp://www.greenmedinfo.com/article/serum-vitamin-d-levels-have-independent-inverse-association-cardiovascular-disease-and-allhttp://www.greenmedinfo.com/article/serum-vitamin-d-levels-have-independent-inverse-association-cardiovascular-disease-and-allhttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref6http://www.greenmedinfo.com/article/both-high-and-low-concentrations-plasma-25ohd-are-associated-elevated-risks-overall-andhttp://www.greenmedinfo.com/article/both-high-and-low-concentrations-plasma-25ohd-are-associated-elevated-risks-overall-andhttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref7http://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref8http://www.greenmedinfo.com/article/low-serum-magnesium-concentrations-predict-cardiovascular-and-all-cause-mortalityhttp://www.greenmedinfo.com/article/low-serum-magnesium-concentrations-predict-cardiovascular-and-all-cause-mortalityhttp://www.greenmedinfo.com/article/low-serum-magnesium-concentrations-predict-cardiovascular-and-all-cause-mortalityhttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref9http://www.greenmedinfo.com/blog/can-pomegranate-keep-you-going-under-knifehttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref10http://www.greenmedinfo.com/substance/pomegranatehttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref11http://www.greenmedinfo.com/article/garlic-reduces-multitude-risk-factors-associated-arteriosclerosis-and-significantly-reduceshttp://www.greenmedinfo.com/article/garlic-reduces-multitude-risk-factors-associated-arteriosclerosis-and-significantly-reduceshttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref12http://www.greenmedinfo.com/article/garlic-inhibits-arteriosclerotic-plaque-formation-vitrohttp://www.greenmedinfo.com/article/garlic-inhibits-arteriosclerotic-plaque-formation-vitro
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    PM(6: 1473G0H0

    'iii Matthe" Budo, unichiro +a&asu, erdinand 8 lores, uta&a ;iihara, Bin u, Ben.amin au,

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    http://www.greenmedinfo.com/article/garlic-inhibits-arteriosclerotic-plaque-formation-vitrohttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref13http://www.greenmedinfo.com/article/aged-garlic-extract-age-inhibits-rate-progression-coronary-calcification-patients-receivinghttp://www.greenmedinfo.com/article/aged-garlic-extract-age-inhibits-rate-progression-coronary-calcification-patients-receivinghttp://www.greenmedinfo.com/article/aged-garlic-extract-age-inhibits-rate-progression-coronary-calcification-patients-receivinghttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref14http://www.greenmedinfo.com/article/high-dose-b-complex-vitamin-supplementation-significantly-reduces-progression-early-stagehttp://www.greenmedinfo.com/article/high-dose-b-complex-vitamin-supplementation-significantly-reduces-progression-early-stagehttp://www.greenmedinfo.com/article/high-dose-b-complex-vitamin-supplementation-significantly-reduces-progression-early-stagehttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref15http://www.greenmedinfo.com/article/b-vitamin-formula-decreases-carotid-artery-thickness-patients-risk-cerebral-ischemiahttp://www.greenmedinfo.com/article/b-vitamin-formula-decreases-carotid-artery-thickness-patients-risk-cerebral-ischemiahttp://www.greenmedinfo.com/article/b-vitamin-formula-decreases-carotid-artery-thickness-patients-risk-cerebral-ischemiahttp://www.greenmedinfo.com/article/b-vitamin-formula-decreases-carotid-artery-thickness-patients-risk-cerebral-ischemiahttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref16http://www.greenmedinfo.com/article/hyperhomocysteinemia-associated-cardiac-pathological-conditionshttp://www.greenmedinfo.com/article/hyperhomocysteinemia-associated-cardiac-pathological-conditionshttp://www.greenmedinfo.com/article/hyperhomocysteinemia-associated-cardiac-pathological-conditionshttp://www.greenmedinfo.com/article/hyperhomocysteinemia-associated-cardiac-pathological-conditionshttps://plus.google.com/u/0/106647364163162243473/about/p/pubhttps://plus.google.com/u/0/106647364163162243473/about/p/pubhttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/gmi-blogs/Sayer%20Jihttp://www.greenmedinfo.com/article/garlic-inhibits-arteriosclerotic-plaque-formation-vitrohttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref13http://www.greenmedinfo.com/article/aged-garlic-extract-age-inhibits-rate-progression-coronary-calcification-patients-receivinghttp://www.greenmedinfo.com/article/aged-garlic-extract-age-inhibits-rate-progression-coronary-calcification-patients-receivinghttp://www.greenmedinfo.com/article/aged-garlic-extract-age-inhibits-rate-progression-coronary-calcification-patients-receivinghttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref14http://www.greenmedinfo.com/article/high-dose-b-complex-vitamin-supplementation-significantly-reduces-progression-early-stagehttp://www.greenmedinfo.com/article/high-dose-b-complex-vitamin-supplementation-significantly-reduces-progression-early-stagehttp://www.greenmedinfo.com/article/high-dose-b-complex-vitamin-supplementation-significantly-reduces-progression-early-stagehttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref15http://www.greenmedinfo.com/article/b-vitamin-formula-decreases-carotid-artery-thickness-patients-risk-cerebral-ischemiahttp://www.greenmedinfo.com/article/b-vitamin-formula-decreases-carotid-artery-thickness-patients-risk-cerebral-ischemiahttp://www.greenmedinfo.com/article/b-vitamin-formula-decreases-carotid-artery-thickness-patients-risk-cerebral-ischemiahttp://www.greenmedinfo.com/article/b-vitamin-formula-decreases-carotid-artery-thickness-patients-risk-cerebral-ischemiahttp://www.greenmedinfo.com/blog/7-ways-prevent-and-even-reverse-heart-disease-nutrition1?page=2#_ednref16http://www.greenmedinfo.com/article/hyperhomocysteinemia-associated-cardiac-pathological-conditionshttp://www.greenmedinfo.com/article/hyperhomocysteinemia-associated-cardiac-pathological-conditionshttp://www.greenmedinfo.com/article/hyperhomocysteinemia-associated-cardiac-pathological-conditionshttps://plus.google.com/u/0/106647364163162243473/about/p/pubhttp://www.greenmedinfo.com/disease/cardiac-mortality
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    e(%er Pa)e +iew Ena%$ed

    +iew the Evidence *i$(ents

    2ein) in the $owest Auarti$e o# vita(in D $eve$s is

    associated with a 3BC increased rate o# a$$&cause(orta$ity

    /$ick here to read the entire a%stract

    Pu%(ed Data: Arch (ntern Med$ 200G Aug 11F17G=14>:1729)3H$ PM(6: 1G7940H7

    *rtic$e Pu%$ished Date: Aug 11, 200G

    Study Ty"e: Meta Analysis

    *dditiona$ : AC=23G>

    Diseases: Cardiac Mortality : CI=H03> : AC=7H>, Mortality: All)Cause : CI=7@@> : AC=44>,Eitamin 6 6eiciency

    CI=@94> : AC=@4>

    2ein) in the $owest Auarti$e o# vita(in D $eve$s is

    associated with a 3BC increased rate o# a$$&cause

    (orta$ity & 1reened5n#o Su((aryAstract +itle:

    24)hydro'y!itamin 6 le!els and the ris& o mortality in the general population$

    Astract %ource:

    Arch (ntern Med$ 200G Aug 11F17G=14>:1729)3H$ PM(6:1G7940H7

    Astract Author=s>:

    Michal Melamed, rin 6 Michos, Wendy Post, Brad Astor

    Article Ailiation:

    http://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.ncbi.nlm.nih.gov/pubmed/18695076http://www.greenmedinfo.com/substance/vitamin-dhttp://www.greenmedinfo.com/substance/vitamin-dhttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/mortality-all-causehttp://www.greenmedinfo.com/disease/vitamin-d-deficiencyhttp://www.greenmedinfo.com/disease/vitamin-d-deficiencyhttp://www.greenmedinfo.com/disease/vitamin-d-deficiencyhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.ncbi.nlm.nih.gov/pubmed/18695076http://www.ncbi.nlm.nih.gov/pubmed/18695076http://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.ncbi.nlm.nih.gov/pubmed/18695076http://www.greenmedinfo.com/substance/vitamin-dhttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/mortality-all-causehttp://www.greenmedinfo.com/disease/vitamin-d-deficiencyhttp://www.greenmedinfo.com/disease/vitamin-d-deficiencyhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.greenmedinfo.com/article/being-lowest-quartile-vitamin-d-levels-associated-26-increased-rate-all-cause-mortalityhttp://www.ncbi.nlm.nih.gov/pubmed/18695076
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    6i!ision o ;ephrology, 6epartment o Medicine, Alert instein College o Medicine, 1300 Morris Par& A!e,

    llmann 714, Bron', ; 10@71, %A$ mmelamedRaecom$yu$edu

    Astract:

    BACI8/;6: (n patients undergoing dialysis, therapy "ith calcitriol or paricalcitol or other !itamin 6 agentis associated "ith reduced mortality$ /ser!ational data suggests that lo" 24)hydro'y!itamin 6 le!els =24/6

    are associated "ith diaetes mellitus, hypertension, and cancers$ o"e!er, "hether lo" serum 24=/>6 le!els a

    associated "ith mortality in the general population is un&no"n$

    M+/6%: We tested the association o lo" 24=/>6 le!els "ith all)cause, cancer, and cardio!ascular disease

    =CE6> mortality in 13 331 nationally representati!e adults 20 years or older rom the +hird ;ational ealth and;utrition 'amination %ur!ey =;A;% (((> lin&ed mortality iles$ Participant !itamin 6 le!els "ere collected

    rom 19GG through 199@, and indi!iduals "ere passi!ely ollo"ed or mortality through 2000$

    8%+%: (n cross)sectional multi!ariate analyses, increasing age, emale se', non"hite race

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    Su%stance Na(e /. */ DD

    1GX)lycyrrhetinic Acid 1 1

    2)Metho'yestradiol 1 1

    @)%hogaol 1 1

    4)+P =4)ydro'ytryptophan> 7@ 9

    4)hydro'ytryptamides 1 1

    4)Methyltetrahydroolate =M+> @2 4

    7)%hogaol 1 1H)epi)nemorosone 1 1

    H)Ieto 6A 20 2

    Aelmoschus moschatus 2 1

    Acacia araica 30 1

    Acacia catechu 3 3

    Acai 2H H

    Acerola 10 H

    Acetic Acid 14 2

    Acetyl)l)carnitine 7H2 3G

    Achillea ragrantissima 2 2

    Achyranthes 10 1

    Achyrocline alata 1 1

    Acorus calamus 11 7

    Adu&i ean 14 4

    Arican Basil 2 1

    Agaricus BlaDei 42 12

    Agaricus rasiliensis 1@ 3

    Ageratina 10 1

    Agosterol A 1 1

    Agrimony 14 12

    ACC @G 1H

    Ailanthus altissima 2 1

    A.uga 3 2

    A."ain @ 3

    AA =Alpha)inolenic Acid> @G G

    Alanine 31 @

    AliDia gummiera 1 1

    Alchornea cordiolia 1 1Alcohol G2 9

    Alcoholic Be!erages 110 2@

    Aleurone 2 2

    Alala 20 7

    Algae 3G 14

    Alisma 10 1

    Al&aline Water 34 11

    http://www.greenmedinfo.com/greenmed/display/substance?sort=desc&order=Substance+Namehttp://www.greenmedinfo.com/greenmed/display/substance?sort=asc&order=CKhttp://www.greenmedinfo.com/greenmed/display/substance?sort=asc&order=AChttp://www.greenmedinfo.com/substance/18%CE%B2-glycyrrhetinic-acidhttp://www.greenmedinfo.com/substance/2-methoxyestradiolhttp://www.greenmedinfo.com/substance/4-shogaolhttp://www.greenmedinfo.com/substance/5-htp-5-hydroxytryptophanhttp://www.greenmedinfo.com/substance/5-hydroxytryptamideshttp://www.greenmedinfo.com/substance/5-methyltetrahydrofolate-mthfhttp://www.greenmedinfo.com/substance/6-shogaolhttp://www.greenmedinfo.com/substance/7-epi-nemorosonehttp://www.greenmedinfo.com/substance/7-keto-dheahttp://www.greenmedinfo.com/substance/abelmoschus-moschatushttp://www.greenmedinfo.com/substance/acacia-arabicahttp://www.greenmedinfo.com/substance/acacia-catechuhttp://www.greenmedinfo.com/substance/acaihttp://www.greenmedinfo.com/substance/acerolahttp://www.greenmedinfo.com/substance/acetic-acidhttp://www.greenmedinfo.com/substance/acetyl-l-carnitinehttp://www.greenmedinfo.com/substance/achillea-fragrantissimahttp://www.greenmedinfo.com/substance/achyrantheshttp://www.greenmedinfo.com/substance/achyrocline-alatahttp://www.greenmedinfo.com/substance/acorus-calamushttp://www.greenmedinfo.com/substance/aduki-beanhttp://www.greenmedinfo.com/substance/african-basilhttp://www.greenmedinfo.com/substance/agaricus-blazeihttp://www.greenmedinfo.com/substance/agaricus-brasiliensishttp://www.greenmedinfo.com/substance/ageratinahttp://www.greenmedinfo.com/substance/agosterolhttp://www.greenmedinfo.com/substance/agrimonyhttp://www.greenmedinfo.com/substance/ahcchttp://www.greenmedinfo.com/substance/ailanthus-altissimahttp://www.greenmedinfo.com/substance/ajugahttp://www.greenmedinfo.com/substance/ajwainhttp://www.greenmedinfo.com/substance/ala-alpha-linolenic-acidhttp://www.greenmedinfo.com/substance/alaninehttp://www.greenmedinfo.com/substance/albizia-gummiferahttp://www.greenmedinfo.com/substance/alchornea-cordifoliahttp://www.greenmedinfo.com/substance/alcoholhttp://www.greenmedinfo.com/substance/alcoholic-beverageshttp://www.greenmedinfo.com/substance/aleuronehttp://www.greenmedinfo.com/substance/alfalfahttp://www.greenmedinfo.com/substance/algaehttp://www.greenmedinfo.com/substance/alismahttp://www.greenmedinfo.com/substance/alkaline-waterhttp://www.greenmedinfo.com/product/downloadable-document-alkaline-waterhttp://www.greenmedinfo.com/product/downloadable-document-alcoholhttp://www.greenmedinfo.com/product/downloadable-document-acetyl-l-carnitinehttp://www.greenmedinfo.com/product/downloadable-document-acaihttp://www.greenmedinfo.com/product/downloadable-document-7-keto-dheahttp://www.greenmedinfo.com/product/downloadable-document-5-htp-5-hydroxytryptophanhttp://www.greenmedinfo.com/greenmed/display/substance?sort=desc&order=Substance+Namehttp://www.greenmedinfo.com/greenmed/display/substance?sort=desc&order=Substance+Namehttp://www.greenmedinfo.com/greenmed/display/substance?sort=asc&order=CKhttp://www.greenmedinfo.com/greenmed/display/substance?sort=asc&order=AChttp://www.greenmedinfo.com/substance/18%CE%B2-glycyrrhetinic-acidhttp://www.greenmedinfo.com/substance/2-methoxyestradiolhttp://www.greenmedinfo.com/substance/4-shogaolhttp://www.greenmedinfo.com/substance/5-htp-5-hydroxytryptophanhttp://www.greenmedinfo.com/substance/5-hydroxytryptamideshttp://www.greenmedinfo.com/substance/5-methyltetrahydrofolate-mthfhttp://www.greenmedinfo.com/substance/6-shogaolhttp://www.greenmedinfo.com/substance/7-epi-nemorosonehttp://www.greenmedinfo.com/substance/7-keto-dheahttp://www.greenmedinfo.com/substance/abelmoschus-moschatushttp://www.greenmedinfo.com/substance/acacia-arabicahttp://www.greenmedinfo.com/substance/acacia-catechuhttp://www.greenmedinfo.com/substance/acaihttp://www.greenmedinfo.com/substance/acerolahttp://www.greenmedinfo.com/substance/acetic-acidhttp://www.greenmedinfo.com/substance/acetyl-l-carnitinehttp://www.greenmedinfo.com/substance/achillea-fragrantissimahttp://www.greenmedinfo.com/substance/achyrantheshttp://www.greenmedinfo.com/substance/achyrocline-alatahttp://www.greenmedinfo.com/substance/acorus-calamushttp://www.greenmedinfo.com/substance/aduki-beanhttp://www.greenmedinfo.com/substance/african-basilhttp://www.greenmedinfo.com/substance/agaricus-blazeihttp://www.greenmedinfo.com/substance/agaricus-brasiliensishttp://www.greenmedinfo.com/substance/ageratinahttp://www.greenmedinfo.com/substance/agosterolhttp://www.greenmedinfo.com/substance/agrimonyhttp://www.greenmedinfo.com/substance/ahcchttp://www.greenmedinfo.com/substance/ailanthus-altissimahttp://www.greenmedinfo.com/substance/ajugahttp://www.greenmedinfo.com/substance/ajwainhttp://www.greenmedinfo.com/substance/ala-alpha-linolenic-acidhttp://www.greenmedinfo.com/substance/alaninehttp://www.greenmedinfo.com/substance/albizia-gummiferahttp://www.greenmedinfo.com/substance/alchornea-cordifoliahttp://www.greenmedinfo.com/substance/alcoholhttp://www.greenmedinfo.com/substance/alcoholic-beverageshttp://www.greenmedinfo.com/substance/aleuronehttp://www.greenmedinfo.com/substance/alfalfahttp://www.greenmedinfo.com/substance/algaehttp://www.greenmedinfo.com/substance/alismahttp://www.greenmedinfo.com/substance/alkaline-water
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    Su%stance Na(e /. */ DD

    Allicin @92 20

    Allomelanins 1 1

    Allspice H 4

    Almond 10H 14

    Alnus pendula 1 1

    Aloe !ahome 2 1

    Aloe Eera 201 @@Alpha Ietoglutarate 40 4

    Alpha)Carotene 30 3

    Alpha)ipoic Acid 3G@ G2

    Alpha)naphthola!one 2 1

    Alpinia galanga 4 @

    Alternanthera pungens 10 1

    Amaranth 20 G

    Amino Acids 100 17

    Amino Acids: Branched Chain 12 2

    Amla ruit 41 2G

    Amurensin 4 1

    Amygdalin H 4

    Anandamide 2 2

    Andrographis G1 34

    Andrographolide 2 2

    Anemarrhena asphodeloides 7 3

    Angelica 7H 24

    Anise 29 G

    Anthera'anthin 1 1

    Anthocyanins 47 19

    Anthurium schlechtendalii 2 1

    Antineoplaston A3 3 1

    Antineoplaston A4 3 1

    Antineoplaston A%2)1 =@:1 mi'ture o phenylacetic acid and phenylacetylglutamine> 92 1

    Antineoplaston A%2)4 1 1

    Antineoplastons 13@ 37

    Antio'idant ormulas @GH H3

    Antio'idants: at %olule 1 1Antrodia camphorata H @

    Antrodia Camphorate 2 1

    Antrodia cinnamomea 1 1

    Apigenin H7 41

    Apple Cider Einegar @ 2

    Apple Pectin 44 13

    Apple Polyphenols @ 2

    http://www.greenmedinfo.com/substance/allicinhttp://www.greenmedinfo.com/substance/allomelaninshttp://www.greenmedinfo.com/substance/allspicehttp://www.greenmedinfo.com/substance/almondhttp://www.greenmedinfo.com/substance/alnus-pendulahttp://www.greenmedinfo.com/substance/aloe-vahombehttp://www.greenmedinfo.com/substance/aloe-verahttp://www.greenmedinfo.com/substance/alpha-ketoglutaratehttp://www.greenmedinfo.com/substance/alpha-carotenehttp://www.greenmedinfo.com/substance/alpha-lipoic-acidhttp://www.greenmedinfo.com/substance/alpha-naphthoflavonehttp://www.greenmedinfo.com/substance/alpinia-galangahttp://www.greenmedinfo.com/substance/alternanthera-pungenshttp://www.greenmedinfo.com/substance/amaranthhttp://www.greenmedinfo.com/substance/amino-acidshttp://www.greenmedinfo.com/substance/amino-acids-branched-chainhttp://www.greenmedinfo.com/substance/amla-fruithttp://www.greenmedinfo.com/substance/amurensin-ghttp://www.greenmedinfo.com/substance/amygdalinhttp://www.greenmedinfo.com/substance/anandamidehttp://www.greenmedinfo.com/substance/andrographishttp://www.greenmedinfo.com/substance/andrographolidehttp://www.greenmedinfo.com/substance/anemarrhena-asphodeloideshttp://www.greenmedinfo.com/substance/angelicahttp://www.greenmedinfo.com/substance/anisehttp://www.greenmedinfo.com/substance/antheraxanthinhttp://www.greenmedinfo.com/substance/anthocyaninshttp://www.greenmedinfo.com/substance/anthurium-schlechtendaliihttp://www.greenmedinfo.com/substance/antineoplaston-a3http://www.greenmedinfo.com/substance/antineoplaston-a5http://www.greenmedinfo.com/substance/antineoplaston-as2-1-41-mixture-phenylacetic-acid-and-phenylacetylglutaminehttp://www.greenmedinfo.com/substance/antineoplaston-as2-5http://www.greenmedinfo.com/substance/antineoplastonshttp://www.greenmedinfo.com/substance/antioxidant-formulashttp://www.greenmedinfo.com/substance/antioxidants-fat-solublehttp://www.greenmedinfo.com/substance/antrodia-camphoratahttp://www.greenmedinfo.com/substance/antrodia-camphoratehttp://www.greenmedinfo.com/substance/antrodia-cinnamomeahttp://www.greenmedinfo.com/substance/apigeninhttp://www.greenmedinfo.com/substance/apple-cider-vinegarhttp://www.greenmedinfo.com/substance/apple-pectinhttp://www.greenmedinfo.com/substance/apple-polyphenolshttp://www.greenmedinfo.com/product/downloadable-document-apple-pectinhttp://www.greenmedinfo.com/product/downloadable-document-antioxidant-formulashttp://www.greenmedinfo.com/product/downloadable-document-angelicahttp://www.greenmedinfo.com/product/downloadable-document-amla-fruithttp://www.greenmedinfo.com/product/downloadable-document-alpha-lipoic-acidhttp://www.greenmedinfo.com/product/downloadable-document-aloe-verahttp://www.greenmedinfo.com/substance/allicinhttp://www.greenmedinfo.com/substance/allomelaninshttp://www.greenmedinfo.com/substance/allspicehttp://www.greenmedinfo.com/substance/almondhttp://www.greenmedinfo.com/substance/alnus-pendulahttp://www.greenmedinfo.com/substance/aloe-vahombehttp://www.greenmedinfo.com/substance/aloe-verahttp://www.greenmedinfo.com/substance/alpha-ketoglutaratehttp://www.greenmedinfo.com/substance/alpha-carotenehttp://www.greenmedinfo.com/substance/alpha-lipoic-acidhttp://www.greenmedinfo.com/substance/alpha-naphthoflavonehttp://www.greenmedinfo.com/substance/alpinia-galangahttp://www.greenmedinfo.com/substance/alternanthera-pungenshttp://www.greenmedinfo.com/substance/amaranthhttp://www.greenmedinfo.com/substance/amino-acidshttp://www.greenmedinfo.com/substance/amino-acids-branched-chainhttp://www.greenmedinfo.com/substance/amla-fruithttp://www.greenmedinfo.com/substance/amurensin-ghttp://www.greenmedinfo.com/substance/amygdalinhttp://www.greenmedinfo.com/substance/anandamidehttp://www.greenmedinfo.com/substance/andrographishttp://www.greenmedinfo.com/substance/andrographolidehttp://www.greenmedinfo.com/substance/anemarrhena-asphodeloideshttp://www.greenmedinfo.com/substance/angelicahttp://www.greenmedinfo.com/substance/anisehttp://www.greenmedinfo.com/substance/antheraxanthinhttp://www.greenmedinfo.com/substance/anthocyaninshttp://www.greenmedinfo.com/substance/anthurium-schlechtendaliihttp://www.greenmedinfo.com/substance/antineoplaston-a3http://www.greenmedinfo.com/substance/antineoplaston-a5http://www.greenmedinfo.com/substance/antineoplaston-as2-1-41-mixture-phenylacetic-acid-and-phenylacetylglutaminehttp://www.greenmedinfo.com/substance/antineoplaston-as2-5http://www.greenmedinfo.com/substance/antineoplastonshttp://www.greenmedinfo.com/substance/antioxidant-formulashttp://www.greenmedinfo.com/substance/antioxidants-fat-solublehttp://www.greenmedinfo.com/substance/antrodia-camphoratahttp://www.greenmedinfo.com/substance/antrodia-camphoratehttp://www.greenmedinfo.com/substance/antrodia-cinnamomeahttp://www.greenmedinfo.com/substance/apigeninhttp://www.greenmedinfo.com/substance/apple-cider-vinegarhttp://www.greenmedinfo.com/substance/apple-pectinhttp://www.greenmedinfo.com/substance/apple-polyphenols
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    Su%stance Na(e /. */ DD

    Apple: olden 6elicious 2 2

    Apples 1H9 4H

    Apricot 12 7

    Apricot Iernel 2 1

    Araic gum 1@ 3

    Arainogalactan 13 3

    Araino'ylans 1 1Arachidin)1 1 1

    Arachidonic Acid 4 3

    Arachidonyl thanolamide =AA> 2 2

    Argan /il 2 1

    Argania spinosa =Argan> 13 G

    Arginine 9H0 179

    Ar.una H9 H

    Arnica 1@7 23

    Arro"root 10 1

    Pu%(ed Data: ;utr 8es$ 2009 /ctF29=10>:797)H0@$ PM(6: 1991H@@G

    *rtic$e Pu%$ished Date: /ct 01, 2009

    Study Ty"e: Meta Analysis

    *dditiona$ : AC=319>, /mega)7 atty Acids : CI=30> : AC=2>

    Diseases: Cardiac Mortality : CI=H03> : AC=7H>, Coronary Artery 6isease : CI=1304> : AC=137>

    Phar(aco$o)ica$ *ctions: Cardioprotecti!e : CI=H02> : AC=197>

    /ardiovascu$ar risks are si)ni#icant$y $ower in

    individua$s who excrete hi)her $eve$s o# (a)nesiu(

    and taurine, indicatin) their "rotective ro$es4/$ick here to read the entire a%stract

    /ardiovascu$ar risks are si)ni#icant$y $ower inindividua$s who excrete hi)her $eve$s o# (a)nesiu(

    and taurine, indicatin) their "rotective ro$es4&

    1reened5n#o Su((aryAstract +itle:

    http://www.greenmedinfo.com/substance/apple-golden-delicioushttp://www.greenmedinfo.com/substance/appleshttp://www.greenmedinfo.com/substance/apricothttp://www.greenmedinfo.com/substance/apricot-kernelhttp://www.greenmedinfo.com/substance/arabic-gumhttp://www.greenmedinfo.com/substance/arabinogalactanhttp://www.greenmedinfo.com/substance/arabinoxylanshttp://www.greenmedinfo.com/substance/arachidin-1http://www.greenmedinfo.com/substance/arachidonic-acidhttp://www.greenmedinfo.com/substance/arachidonyl-ethanolamide-aeahttp://www.greenmedinfo.com/substance/argan-oilhttp://www.greenmedinfo.com/substance/argania-spinosa-arganhttp://www.greenmedinfo.com/substance/argininehttp://www.greenmedinfo.com/substance/arjunahttp://www.greenmedinfo.com/substance/arnicahttp://www.greenmedinfo.com/substance/arrowroothttp://www.ncbi.nlm.nih.gov/pubmed/19917448http://www.greenmedinfo.com/substance/omega-3-fatty-acidshttp://www.greenmedinfo.com/substance/omega-6-fatty-acidshttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/pharmacological-action/cardioprotectivehttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/product/downloadable-document-arnicahttp://www.greenmedinfo.com/product/downloadable-document-argininehttp://www.greenmedinfo.com/product/downloadable-document-appleshttp://www.greenmedinfo.com/substance/apple-golden-delicioushttp://www.greenmedinfo.com/substance/appleshttp://www.greenmedinfo.com/substance/apricothttp://www.greenmedinfo.com/substance/apricot-kernelhttp://www.greenmedinfo.com/substance/arabic-gumhttp://www.greenmedinfo.com/substance/arabinogalactanhttp://www.greenmedinfo.com/substance/arabinoxylanshttp://www.greenmedinfo.com/substance/arachidin-1http://www.greenmedinfo.com/substance/arachidonic-acidhttp://www.greenmedinfo.com/substance/arachidonyl-ethanolamide-aeahttp://www.greenmedinfo.com/substance/argan-oilhttp://www.greenmedinfo.com/substance/argania-spinosa-arganhttp://www.greenmedinfo.com/substance/argininehttp://www.greenmedinfo.com/substance/arjunahttp://www.greenmedinfo.com/substance/arnicahttp://www.greenmedinfo.com/substance/arrowroothttp://www.ncbi.nlm.nih.gov/pubmed/19917448http://www.greenmedinfo.com/substance/omega-3-fatty-acidshttp://www.greenmedinfo.com/substance/omega-6-fatty-acidshttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/pharmacological-action/cardioprotectivehttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higherhttp://www.greenmedinfo.com/article/cardiovascular-risks-are-significantly-lower-individuals-who-excrete-higher
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    o" cardio!ascular ris&s in the middle aged males and emales e'creting greater 2@)hour urinary taurine and

    magnesium in @1 W/)CA86(AC study populations in the "orld$

    Astract %ource:

    Biomed %ci$ 2010F1H %uppl 1:%21$ pu 2010 Aug 2@$ PM(6: 20G0@497

    Astract Author=s>:

    u&io amori, +a&ashi +aguchi, ide&i Mori, Mari Mori

    Article Ailiation:

    Mu&oga"a Women*s ni!ersity (nstitute or World ealth 6e!elopment, ;ishinomiya, yogo, 773G1@3, apan$

    yamoriRcardiacstudy$com

    Astract:

    BACI8/;6: %ince taurine =+> administration "as pro!en to decrease lood pressure =BP> and stro&e

    mortality in stro&e)prone spontaneously hypertension rates =%8%P> in the 19G0*s and our W/)coordinatedCA86(AC =Cardio!ascular 6iseases and Alimentary Comparison> %tudy demonstrated that among 4 diet)related

    actors, namely total cholesterol =+)Cho>, ody mass inde' =BM(>, sodium =;a>, magnesium =M>, and + to

    creatinine =Cr> ratio in 2@)hour urine =2@>, oth +,+aurine : CI=1@4> : AC=33>

    Diseases: Cardiac Mortality : CI=H03> : AC=7H>, Cardio!ascular 6iseases : CI=413G> : AC=7@1>

    Phar(aco$o)ica$ *ctions: Cardioprotecti!e : CI=H02> : AC=197>

    http://www.ncbi.nlm.nih.gov/pubmed/20804596http://www.ncbi.nlm.nih.gov/pubmed/20804596http://www.greenmedinfo.com/substance/magnesiumhttp://www.greenmedinfo.com/substance/taurinehttp://www.greenmedinfo.com/substance/taurinehttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/cardiovascular-diseaseshttp://www.greenmedinfo.com/pharmacological-action/cardioprotectivehttp://www.ncbi.nlm.nih.gov/pubmed/20804596http://www.ncbi.nlm.nih.gov/pubmed/20804596http://www.greenmedinfo.com/substance/magnesiumhttp://www.greenmedinfo.com/substance/taurinehttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/cardiovascular-diseaseshttp://www.greenmedinfo.com/pharmacological-action/cardioprotective
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    Dietary su""$e(entation with o(e)a& #atty acids

    reduces the incidence o# sudden cardiac death in

    "atients with (yocardia$ in#arction4/$ick here to read the entire a%stract

    Pu%(ed Data: Ann Med$ 2009F@1=@>:301)10$ PM(6:191@GG3G

    *rtic$e Pu%$ished Date: an 01, 2009

    Study Ty"e: Meta Analysis

    *dditiona$ : AC=319>

    Diseases: Cardiac Arrest : CI=@0> : AC=2>, Cardiac Mortality : CI=H03> : AC=7H>, Coronary Artery 6isease :

    CI=1304> : AC=137>, Myocardial (narction : CI=2732> : AC=11H>

    Phar(aco$o)ica$ *ctions: Cardioprotecti!e : CI=H02> : AC=197>

    Dietary su""$e(entation with o(e)a& #atty acidsreduces the incidence o# sudden cardiac death in

    "atients with (yocardia$ in#arction4& 1reened5n#o

    Su((aryAstract +itle:

    Pre!ention o sudden cardiac death "ith omega)3 atty acids in patients "ith coronary heart disease: a meta)

    analysis o randomiDed controlled trials$

    Astract %ource:

    Ann Med$ 2009F@1=@>:301)10$ PM(6: 191@GG3G

    Astract Author=s>:

    un)+ao Vhao, Tiang Chen, a)Uun %un, Uue)Bin i, Ping Vhang, uan Uu, i)ong uo

    Article Ailiation:

    6epartment o Cardiology, Pe&ing ni!ersity People*s ospital, ;o$ 11 UiDhimen %outh %treet, Bei.ing, China$

    Astract:

    A(M: +o systematically re!ie" trials concerning the eects o omega)3 atty acids on sudden cardiac death =%C6

    cardiac death, and all)cause mortality in coronary heart disease =C6> patients$

    M+/6%: PuMed, mase, and the Cochrane dataase =1977)200H> "ere searched$ We identiied randomiDe

    controlled trials that compared dietary or supplementary inta&e o omega)3 atty acids "ith control diet or placein C6 patients$ ligile studies had at least 7 months o ollo")up data, and cited %C6 as an end)point$ +"o

    re!ie"ers independently assessed methodological ?uality$ Meta)analysis o relati!e ris& "as carried out using the

    random eect model$

    8%+%: ight trials "ere identiied, comprising 20,99H patients$ (n patients "ith prior myocardial inarction=M(>, omega)3 atty acids reduced relati!e ris& =88> o %C6 =88 Z 0$@3F 945 C(: 0$20)0$91>$ (n patients "ith

    http://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.ncbi.nlm.nih.gov/pubmed/19148838http://www.ncbi.nlm.nih.gov/pubmed/19148838http://www.greenmedinfo.com/substance/omega-3-fatty-acidshttp://www.greenmedinfo.com/disease/cardiac-arresthttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/disease/myocardial-infarctionhttp://www.greenmedinfo.com/pharmacological-action/cardioprotectivehttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.ncbi.nlm.nih.gov/pubmed/19148838http://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.ncbi.nlm.nih.gov/pubmed/19148838http://www.greenmedinfo.com/substance/omega-3-fatty-acidshttp://www.greenmedinfo.com/disease/cardiac-arresthttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/disease/myocardial-infarctionhttp://www.greenmedinfo.com/pharmacological-action/cardioprotectivehttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.greenmedinfo.com/article/dietary-supplementation-omega-3-fatty-acids-reduces-incidence-sudden-cardiachttp://www.ncbi.nlm.nih.gov/pubmed/19148838
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    angina, omega)3 atty acids increased 88 o %C6 =88 Z 1$39F 945 C(: 1$01)1$92>$ /!erall, 88 or cardiac death

    and all)cause mortality "ere 0$H1 =945 C(: 0$40)1$00> and 0$HH =945 C(: 0$4G)1$01>, respecti!ely$

    C/;C%(/;%: 6ietary supplementation "ith omega)3 atty acids reduces the incidence o sudden cardiac dea

    in patients "ith M(, ut may ha!e ad!erse eects in angina patients$

    *rtic$e Pu%$ished Date: an 01, 2009

    Study Ty"e: Meta Analysis

    *dditiona$ : AC=319>

    Diseases: Cardiac Arrest : CI=@0> : AC=2>, Cardiac Mortality : CI=H03> : AC=7H>, Coronary Artery 6isease :CI=1304> : AC=137>, Myocardial (narction : CI=2732> : AC=11H>

    Phar(aco$o)ica$ *ctions: Cardioprotecti!e : CI=H02> : AC=197>

    Dou%$in) )$o%a$ vita(in D $eve$s cou$d si)ni#icant$y

    reduce (orta$ity4/$ick here to read the entire a%stract

    Pu%(ed Data: ur Clin ;utr$ 2011 ul 7$ pu 2011 ul 7$ PM(6: 21H31037

    *rtic$e Pu%$ished Date: ul 07, 2011

    Study Ty"e: Meta Analysis

    *dditiona$ : AC=23G>

    Diseases:Arican)American %peciic 6eiciencies : AC=19>, Cardiac Mortality : CI=H03> :

    AC=7H>,Cardio!ascular 6iseases : CI=413G> : AC=7@1>,Mortality: All)Cause : CI=7@@> : AC=44>,8espiratory

    6iseases : CI=1H@> : AC=29>, +uerculosis : CI=244> : AC=@@>,Eitamin 6 6eiciency : CI=@94> : AC=@4>Thera"eutic *ctions: %unlight e'posure : CI=@32> : AC=39>

    Dou%$in) )$o%a$ vita(in D $eve$s cou$d si)ni#icant$y

    reduce (orta$ity4 & 1reened5n#o Su((aryAstract +itle:

    An estimate o the gloal reduction in mortality rates through douling !itamin 6 le!els$

    Astract %ource:ur Clin ;utr$ 2011 ul 7$ pu 2011 ul 7$ PM(6: 21H31037

    Astract Author=s>:

    W B rant

    Article Ailiation:

    %unlight, ;utrition, and ealth 8esearch Center, %an rancisco, CA, %A$

    Astract:

    http://www.greenmedinfo.com/substance/omega-3-fatty-acidshttp://www.greenmedinfo.com/disease/cardiac-arresthttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/disease/myocardial-infarctionhttp://www.greenmedinfo.com/pharmacological-action/cardioprotectivehttp://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.ncbi.nlm.nih.gov/pubmed/21731036http://www.greenmedinfo.com/substance/vitamin-dhttp://www.greenmedinfo.com/substance/vitamin-dhttp://www.greenmedinfo.com/disease/african-american-specific-deficienciesdiseaseshttp://www.greenmedinfo.com/disease/african-american-specific-deficienciesdiseaseshttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/cardiovascular-diseaseshttp://www.greenmedinfo.com/disease/cardiovascular-diseaseshttp://www.greenmedinfo.com/disease/mortality-all-causehttp://www.greenmedinfo.com/disease/mortality-all-causehttp://www.greenmedinfo.com/disease/respiratory-diseaseshttp://www.greenmedinfo.com/disease/respiratory-diseaseshttp://www.greenmedinfo.com/disease/respiratory-diseaseshttp://www.greenmedinfo.com/disease/tuberculosishttp://www.greenmedinfo.com/disease/vitamin-d-deficiencyhttp://www.greenmedinfo.com/disease/vitamin-d-deficiencyhttp://www.greenmedinfo.com/therapeutic-action/sunlight-exposurehttp://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.ncbi.nlm.nih.gov/pubmed/21731036http://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.ncbi.nlm.nih.gov/pubmed/21731036http://www.greenmedinfo.com/substance/vitamin-dhttp://www.greenmedinfo.com/disease/african-american-specific-deficienciesdiseaseshttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/cardiovascular-diseaseshttp://www.greenmedinfo.com/disease/mortality-all-causehttp://www.greenmedinfo.com/disease/respiratory-diseaseshttp://www.greenmedinfo.com/disease/respiratory-diseaseshttp://www.greenmedinfo.com/disease/tuberculosishttp://www.greenmedinfo.com/disease/vitamin-d-deficiencyhttp://www.greenmedinfo.com/therapeutic-action/sunlight-exposurehttp://www.greenmedinfo.com/substance/omega-3-fatty-acidshttp://www.greenmedinfo.com/disease/cardiac-arresthttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/disease/myocardial-infarctionhttp://www.greenmedinfo.com/pharmacological-action/cardioprotectivehttp://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.greenmedinfo.com/article/doubling-global-vitamin-d-levels-could-significantly-reduce-mortalityhttp://www.ncbi.nlm.nih.gov/pubmed/21731036
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    Bac&ground

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    Ex"osure to iso#$avone&containin) soy "roducts (ay

    i("rove endothe$ia$ #unction4 & 1reened5n#o

    Su((aryAstract +itle:

    'posure to isola!one)containing soy products and endothelial unction: A Bayesian meta)analysis o randomiDe

    controlled trials$Astract %ource:

    ;utr Meta Cardio!asc 6is$ 2010 Aug 1@$ pu 2010 Aug 1@$ PM(6: 20H09414

    Astract Author=s>:

    6 P Bea!ers, I M Bea!ers, M Miller, %tamey, M Messina

    Article Ailiation:

    6epartment o Biostatistical %ciences, Wa&e orest ni!ersity %chool o Medicine, Winston)%alem, ;C, %A$

    Astract:

    BACI8/;6 A;6 A(M%: +o determine "hether and to "hat degree e'posure to isola!one)containing soyproducts aects $ ndothelial dysunction has een identiied as an independent coronary heart disease ris&

    actor and a strong predictor o long)term cardio!ascular moridity and mortality$ 6ata on the eects o e'posure

    to isola!one)containing soy products on are conlicting$ M+/6% A;6 8%+%: A comprehensi!e

    literature search "as conducted using the PBM6 dataase =;ational irary o Medicine, Bethesda, M6>inclusi!ely through August 21, 2009 on 8C+s using the &ey"ords: soy, isola!one, phytoestrogen, , lo"

    mediated !asodilation, and M6$ A Bayesian meta)analysis "as conducted to pro!ide a comprehensi!e account

    the eect o isola!one)containing soy products on , as measured y M6$ A total o 1H 8C+s "ere selected aha!ing suicient data or study inclusion$ +he o!erall mean asolute change in M6 =945 Bayesian C(> or

    isola!one)containing soy product inter!entions "as 1$145 =)0$42, 2$H4>$ When the eects o separate inter!entio

    "ere considered, the treatment eect or isolated isola!ones "as 1$9G5 =0$0H, 3$9H> compared to 0$H25 =)1$39,

    2$90> or isola!one)containing soy protein$ +he models "ere not impro!ed "hen considering study)speciic eesuch as cu measurement location, prescried dietary modiication, and impaired aseline M6$ C/;C%(/;

    Cumulati!e e!idence rom the 8C+s included in this meta)analysis indicates that e'posure to soy isola!ones can

    modestly, ut signiicantly, impro!e as measured y M6$ +hereore, e'posure to isola!one supplements maeneicially inluence !ascular health$

    *rtic$e Pu%$ished Date: Aug 1@, 2010

    Study Ty"e: Meta Analysis

    *dditiona$ : AC=12@>,phytoestrogens : CI=799> : AC=210>,%oy : CI=17GG> : AC=340>,

    %oy Protein : CI=230H> : AC=47>

    Diseases: Cardiac Mortality : CI=H03> : AC=7H>, Coronary Artery 6isease : CI=1304> : AC=137>,ndothelial

    6ysunction : CI=G9H> : AC=1H3>

    http://www.greenmedinfo.com/article/exposure-isoflavone-containing-soy-products-may-improve-endothelial-functionhttp://www.greenmedinfo.com/article/exposure-isoflavone-containing-soy-products-may-improve-endothelial-functionhttp://www.ncbi.nlm.nih.gov/pubmed/20709515http://www.greenmedinfo.com/substance/isoflavoneshttp://www.greenmedinfo.com/substance/phytoestrogenshttp://www.greenmedinfo.com/substance/phytoestrogenshttp://www.greenmedinfo.com/substance/soyhttp://www.greenmedinfo.com/substance/soyhttp://www.greenmedinfo.com/substance/soy-proteinhttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/disease/endothelial-dysfunctionhttp://www.greenmedinfo.com/disease/endothelial-dysfunctionhttp://www.greenmedinfo.com/disease/endothelial-dysfunctionhttp://www.greenmedinfo.com/article/exposure-isoflavone-containing-soy-products-may-improve-endothelial-functionhttp://www.greenmedinfo.com/article/exposure-isoflavone-containing-soy-products-may-improve-endothelial-functionhttp://www.ncbi.nlm.nih.gov/pubmed/20709515http://www.greenmedinfo.com/substance/isoflavoneshttp://www.greenmedinfo.com/substance/phytoestrogenshttp://www.greenmedinfo.com/substance/soyhttp://www.greenmedinfo.com/substance/soy-proteinhttp://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/coronary-artery-diseasehttp://www.greenmedinfo.com/disease/endothelial-dysfunctionhttp://www.greenmedinfo.com/disease/endothelial-dysfunction
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    5ntensive )$ucose $owerin) treat(ent increases a$$

    cause (orta$ity, cardiovascu$ar death, and

    (icrovascu$ar events in ty"e 3 dia%etes4/$ick here to read the entire a%stract

    Pu%(ed Data: BM$ 2011 F3@3:d@179$ pu 2011 ul 27$ PM(6: 21H91@94

    *rtic$e Pu%$ished Date: an 01, 2011

    Study Ty"e: Meta Analysis

    *dditiona$ : AC=7H>, Cardio!ascular 6iseases : CI=413G> : AC=7@1>, 6iaetes Mellit

    +ype 2 : CI=340H> : AC=3@1>, Myocardial (narction : CI=2732> : AC=11H>

    Pro%$e( Su%stances:Anti)diaetic drugs : CI=22> : AC=2>

    5ntensive )$ucose $owerin) treat(ent increases a$$

    cause (orta$ity, cardiovascu$ar death, and(icrovascu$ar events in ty"e 3 dia%etes4&

    1reened5n#o Su((aryAstract +itle:

    ect o intensi!e glucose lo"ering treatment on all cause mortality, cardio!ascular death, and micro!ascular

    e!ents in type 2 diaetes: meta)analysis o randomised controlled trials$

    Astract %ource:

    BM$ 2011 F3@3:d@179$ pu 2011 ul 27$ PM(6: 21H91@94

    Astract Author=s>:

    8Qmy Boussageon, +heodora Be.an)Angoul!ant, Mitra %aadatian)lahi, %andrine aont, Claire Bergeonneau,

    BehrouD Iassa\, %yl!ie rpeldinger, ames M Wright, ran]ois ueyier, Catherine Cornu

    Article Ailiation:

    6epartment o eneral Medicine, ni!ersitQ Claude Bernard yon 1, yon, rance$

    Astract:

    /BC+(E: +o determine all cause mortality and deaths rom cardio!ascular e!ents related to intensi!e glucos

    lo"ering treatment in people "ith type 2 diaetes$

    6%(;: Meta)analysis o randomised controlled trials$

    6A+A %/8C%: Medline, mase, and the Cochrane dataase o systematic re!ie"s$

    %+6 %C+(/;: 8andomised controlled trials that assessed the eect o intensi!e glucose lo"eringtreatment on cardio!ascular e!ents and micro!ascular complications in adults =^ 1G years> "ith type 2 diaetes$

    6A+A U+8AC+(/;: Primary end points "ere all cause mortality and death rom cardio!ascular causes$

    %econdary end points "ere se!ere hypoglycaemia and macro!ascular and micro!ascular e!ents$ %ynthesis o

    http://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.ncbi.nlm.nih.gov/pubmed/21791495http://www.ncbi.nlm.nih.gov/pubmed/21791495http://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/cardiovascular-diseaseshttp://www.greenmedinfo.com/disease/diabetes-mellitus-type-2http://www.greenmedinfo.com/disease/diabetes-mellitus-type-2http://www.greenmedinfo.com/disease/myocardial-infarctionhttp://www.greenmedinfo.com/toxic-ingredient/anti-diabetic-drugshttp://www.greenmedinfo.com/toxic-ingredient/anti-diabetic-drugshttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.ncbi.nlm.nih.gov/pubmed/21791495http://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.ncbi.nlm.nih.gov/pubmed/21791495http://www.greenmedinfo.com/disease/cardiac-mortalityhttp://www.greenmedinfo.com/disease/cardiovascular-diseaseshttp://www.greenmedinfo.com/disease/diabetes-mellitus-type-2http://www.greenmedinfo.com/disease/diabetes-mellitus-type-2http://www.greenmedinfo.com/disease/myocardial-infarctionhttp://www.greenmedinfo.com/toxic-ingredient/anti-diabetic-drugshttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.greenmedinfo.com/article/intensive-glucose-lowering-treatment-increases-all-cause-mortality-cardiovascular-death-andhttp://www.ncbi.nlm.nih.gov/pubmed/21791495
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    results 8esults are reported as ris& ratios "ith 995 conidence inter!als$ %tatistical heterogeneity et"een trials "

    assessed "ith _=2>, `=2>, and (=2> statistics$ A i'ed eect model "as used to assess the eect on the outcomes o

    intensi!e glucose lo"ering !ersus standard treatment$ +he ?uality o clinical trials "as assessed y the adad scor

    8%+%: 13 studies "ere included$ / 3@,433 patients, 1G,314 recei!ed intensi!e glucose lo"ering treatment a17,21G standard treatment$ (ntensi!e treatment did not signiicantly aect all cause mortality =ris& ratio 1$0@, 995

    conidence inter!al 0$91 to 1$19> or cardio!ascular death =1$11, 0$G7 to 1$@3>$ (ntensi!e therapy "as, ho"e!er,

    associated "ith reductions in the ris& o non)atal myocardial inarction =0$G4, 0$H@ to 0$97, PS0$001>, andmicroaluminuria =0$90, 0$G4 to 0$97, PS0$001> ut a more than t"oold increase in the ris& o se!ere

    hypoglycaemia =2$33, 21$72 to 3$37, PS0$001>$ /!er a treatment period o i!e years, 11H to 140 patients "ould

    need to e treated to a!oid one myocardial inarction and 32 to 1@2 patients to a!oid one episode omicroaluminuria, "hereas one se!ere episode o hypoglycaemia "ould occur or e!ery 14 to 42 patients$ (n

    analysis restricted to high ?uality studies =adad scoreY3>, intensi!e treatment "as not associated "ith any

    signiicant ris& o reductions ut resulted in a @H5 increase in ris& o congesti!e heart ailure =PS0$001>$

    C/;C%(/;%: +he o!erall results o this meta)analysis sho" limited eneits o intensi!e glucose lo"eringtreatment on all cause mortality and deaths rom cardio!ascular causes$ We cannot e'clude a 95 reduction or a

    195 increase in all cause mortality and a 1@5 reduction or a @35 increase in cardio!ascular death$ +he eneit:r

    ratio o intensi!e glucose lo"ering treatment in the pre!ention o macro!ascular and micro!ascular e!ents remainuncertain$ +he harm associated "ith se!ere hypoglycaemia might counteralance the potential eneit o intensi!

    glucose lo"ering treatment$ More doule lind randomised controlled trials are needed to estalish the est

    therapeutic approach in people "ith type 2 diaetes$*rtic$e Pu%$ished Date: an 01, 2011

    Study Ty"e: Meta Analysis

    *dditiona$ : AC=7H>, Cardio!ascular 6iseases : CI=413G> : AC=7@1>, 6iaetes Mellit

    +ype 2 : CI=340H> : AC=3@1>, Myocardial (narction : CI=2732> : AC=11H>

    Pro%$e( Su%stances:Anti)diaetic drugs : CI=22> : AC=2>

    Nonsteroida$ antin#$a((atory dru)s increase

    cardiovascu$ar events in "atients a#ter hos"ita$i8ation

    #or serious coronary heart disease4/$ick here to read the entire a%stract

    Pu%(ed Data: Circ Cardio!asc Tual /utcomes$ 2009 MayF2=3>:144)73$ pu 2009 May 4$ PM(6: 20031G32

    *rtic$e Pu%$ished Date: May 01, 2009

    Study Ty"e: Meta Analysis

    *dditiona$ : AC=7H>, Cardio!ascular 6iseases : CI=413G> : AC=7@1>, Coronary Artery

    6isease : CI=1304> : AC=137>,Myocardial (narction : CI=2732> : AC=11H>

    Pro%$e( Su%stances:Celeco'i : CI=40> : AC=@>,6icloenac : CI=H2> : AC=H>,(uproen : CI=172> : AC=19>,;on)%teroidal Anti)(nlammatory 6rugs =;%A(6s> : CI=13G3> : AC=114>, 8oeco'i : CI=70> : AC=4>

    *dverse Phar(aco$o)ica$ *ctions: Cardioto'ic : CI=73G> : AC=H9>

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  • 8/13/2019 7 Ways to Prevent and Even Reverse Heart Disease With Nutrition

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    Nonsteroida$ antin#$a((atory dru)s increase

    cardiovascu$ar events in "atients a#ter hos"ita$i8ation

    #or serious coronary heart disease4& 1reened5n#o

    Su((aryAstract +itle:

    Cardio!ascular ris&s o nonsteroidal antiinlammatory drugs in patients ater hospitaliDation or serious coronary

    heart disease$

    Astract %ource:

    Circ Cardio!asc Tual /utcomes$ 2009 MayF2=3>:144)73$ pu 2009 May 4$ PM(6: 20031G32

    Astract Author=s>:

    Wayne A 8ay, Cristina Earas)orenDo, Cecilia P Chung, ordi Castellsague, Iatherine + Murray, C Michael %teinames 8 6augherty, Patric& Arogast, uis A arcOa)8odrOgueD

    Article Ailiation:

    6epartment o Pre!enti!e Medicine, 6i!ision o Pharmacoepidemiology, Eanderilt ni!ersity %chool o

    Medicine, ;ash!ille, +;, %A$ "ayne$rayR!anderilt$edu

    Astract:

    BACI8/;6: +he cardio!ascular saety o indi!idual nonsteroidal antiinlammatory drugs =;%A(6s> is high

    contro!ersial, particularly in persons "ith serious coronary heart disease$ M+/6% A;6 8%+%: Weconducted a multisite retrospecti!e cohort study o commonly used indi!idual ;%A(6s in +ennessee Medicaid,

    %as&atche"an ealt