/ 4 5 ; - / - J -

SOlIE:NGEIndex to Volume 149

JS e- Pt, 1Ju1y-Anti1965

Editorial Board

ROBERT L. BOWMANMELVIN CALVINJOSEPH W. CHAMBERLAINFARRINGTON DANIELSJOHN T. EDSALLDAVID R. GODDARDEMIL HAURYALEXANDER HOLLAENDERROBERT JASTROWEDWIN M. LERNER II

CLARENCE

EditoriDAEL WOLFLEPublisher

WILLARD F. LIBBYGORDON J. F. MACDONALDEVERETr I. MENDELSOHNNEAL E. MILLERJOHN R. PIERCECOLIN S. PITTENDRIGHKENNETH S. PITZERALEXANDER RICHDEWITT STETTEN, JR.EDWARD L. TATUMM. ZENER

ial StaffHANS NUSSBAUMBusiness Manager

PHILIP H. ABELSONEditor

EARL J. SCHERAGO, Advertising Director

Published by the

American Association for the Advancement of Science1515 Massachusetts Avenue, NW, Washington, D.C. 20005

Printed in Washington, D.C., by National Publishing Company

Copyright 1965 by the American Association for the Advancement of Science

2 July 1965 ~ . I . .Vol. 149, No. 36799

LETTERS Research at NIH: The Wooldridge Report: A. Gellhorn; Full-Time Researchersin Universities: A. B. Metzner; P. A. Ward; C. V. Nelson; Old Ties with theSmithsonian: C. H. Schauer; Why Bibliography?: I. H. Page; Reprints ofReprint Requests Requested: D. H. Hubel et al. .......................... 6

EDITORIAL The Research and Development Pork Barrel

ARTICLES Lasers: A. L. Schawlow ....................................

Early Man in East Africa: P. V. Tobias ..................................

Cell Division and Cancer: A. Szent-Gyorgyi . ..............................

Some Current Problems of Government Science Policy: H. Orlans ..............

NEWS AND COMMENT

BOOK REVIEWS

Soviet Bloc Science: Tale of a Defector Congress: On Researchand igher ducation ........................................... ......

The Barker Index of Crystals, 1951-1964: A. Pabst ......

Sunspots, reviewed by P. R. Wilson; other reviews by R. Siegfried, C. L. Prosser,R. N. Varney, F. A. Geldard, P. M. Ray, D. P. Abbott, H. M. Miner,W. D. Jackson, F. Zwicky ...........................................

REPORTS Infrared Spectra as a Means of Determining Botanical Sources of Amber:J. H. Langenheim and C. W. Beck .. ... ..............................

Uranium-Series Ages of Pacific Atoll Coral: D. L. Thurber et al. ............

Uranium-Series Dating of Corals and Oolites from Bahaman and Florida KeyLimestones: W. S. Broecker and D. L. Thurber ...............

Tritium and Phosphorus-32 in High-Resolution Autoradiography:L. G. Caro and M. Schn8s .........

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:;:;:;:;:::;:;:.:::;:;:::X .:: :.: :::. .:].:- .:: :.::::::::.:- .:i:: .:I:. ....:: :: ...:: ;:,.::: :: :::].

Reduction of Trimethylene Dipyridyl with Illuminated Chloroplasts: C. C. Black ... 62

Psychrometric Measurement of Leaf Water Potential: Lack of Error Attributableto Leaf Permeability: H. D. Barrs ................ ........... 63

Insulin: Inducer of Pyruvate Kinase: G. Weber, N. B. Stamm, E. A. Fisher ..........65

Active Uptake of Sodium by Softshell Turtles (Trionyx spinifer):W. A. Duinson and R. D. Weymiouitl .................67

Mutation of the Blue-Green Alga, Anacysti.s nidutlatns: C. Van Baalen ............ 70

Nature of the Excitatory Sarcoplasmic Reticular Junction: G. Hoyle ................ 70

Lipase: Localization in Adipose Tissue: M. S. Moskowvitz and A. A. Moskowitz .... 72

Activity in Mammalian Peripheral Nerves during Supercooling: L. K. Miller ..........74

Ultrastructure of Vegetative and Reproductive Apices of Chenopodiulm album:E. M. Giflord, Jr., and K. D. Stewart .................................. 75

Ribosomes from Escherichia coli: Lack of Specificity for Viral RNA:J. E. Dahlberg and R. Haselkorn ...................................... 78

Alcohol Dehydrogenase in Drosophila melanogaster: Isozymes and Genetic Variants:E. H. Grell, K. B. Jacobsoni, J. B. Murphy ................................. 80

Abrogation of Allogeneic Inhibition by Cortisone: K. E. Hellstriim, I. Hellstrom,G. Haughton ........................................................ 82

Nonspecific Binding of Complement by Digestion Fragments from AntiviralGamma Giobulin: N. E. Cremer et al. .................................. 84

Respiratory Water Exchange in Two Species of Porpoise: H. N. Coulombe,S. H. Ridgway, W. E. Evanis ........................................ . 86

Stimulus Variables Determining Space Perception in Infants: 7. G. R. Bower ..........88

Cerebral Temperature Changes Accompanying Sexual Activity in the Male Rat:C. D. Hull, J. Garcia, E. Cracchiiolo ....................................... 89

Hypothalamic Motivational Processes as Reflected by Their HippocampalElectrical Correlates: E. Grastyan et al. ........................ ... ... 91

MEETINGS Colston Symposium: Marine Geology and Geophysics: R. S. Dietz;Forthcoming Events .................................................. 94

COVER

Softshell turtle (Trionyx spiniferspinifer) in a sunning position under

..A.:'* Sa lamp. These aquatic turtles are ableJ AEr to breathe under water because oftheir p-haryngeal villi. The animals

ION *IfMI*#iCATION (7) $AT 0 !! .::.regulatesodium concentrations intheir body fluids by active uptake ofsoiu from their fresh-water en-vironEment.See page 67. [William A.

.:xxc Dunson, University of Michigan]

2 July 1965, Volume 149, Number 3679

AMERICAN ASSOCIATION FORTHE ADVANCEMENT OF SCIENCE Th

Science serves its readers as a forum forthe presentation and discussion of impor- Ditant issues related to the advancement ofscience, including the presentation of mi- poutnority or conflicting points of view, rather In 1than by publishing only material on which R&Ea consensus has been reached. Accordingly, senalall articles published in Science-includingeditorials, news and comment, and book theirreviews-are signed and reflect the indi- awaividual views of the authors and not official zatiopoints of view adopted by the AAAS or TIthe institutions with which the authors are thouaffiliated.

portiEditorial Board man

ROBERT L. BOWMAN WILLARD F. LIBBY of hMELVIN CALVIN GORDON J. F. MACDONALD counJOSEPH W. CHAMBERLAIN EVERETT I. MENDELSOHNFARRINGToN D&NIELm NEAL E. MILLER new

JOHN T. EDSALL JOHN R. PIERCE InDAVrD R. GODDARD COLIN S. PITTENDRIGH KimEMIL HAURY KENNETH S. PITZER of oALEXANDER HOLLAENDER ALEXANDER RICH iROBERT JASTROW DEWITT STETTEN, JR. ncuiEDWIN M. LERNER, II EDWARD L. TATUM Duri

CLARENCE M. ZENER only

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EditorPHILIP H. ABELSON tota

natiPublisher Business ManagerDAEL WOLFLE HANS NUSSBAUM C

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theAssistant to the Editor: NANCY TEIMOURIAN scescierNews and Comment: DANIEL S. GREENBERG, onl

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SCIENCE

e Research and Development Pork Barrel

istribution of research and development funds is becoming a majortical issue. One reason is that present distribution is very uneven.

963 one-half of the 50 states received 96.8 percent of all federal) funds while the other 25 divided the remaining 3.2 percent. The 50tors from the have-not states may be expected to attempt to improver states' share. This tendency will be reinforced by a growing generalreness of the role of science and technology in our changing civili-in.he extent of the beneficial effects of federal funds is not clear,igh in some instances the economic stimulus has seemed dispro-:ionately large. In other instances benefits were nominal. However,y of the states whose economies have grown rapidly are recipientsarge sums of federal R&D funds. In contrast, some regions of thisntry not receiving large R&D contracts seem on the road to becomingAppalachias.

i a recent speech at a Midwest Governors' conference, Charlesiball, president of the Midwest Research Institute, outlined problemsne such area. His institute had made a study of a six-state region,uding Arkansas, Iowa, Kansas, Missouri, Nebraska, and Oklahoma.ing the decade 1950-60 the number of jobs in the area had increasedr 2.3 percent as against 14.5 percent for the nation. The averageiily income is now much below the national figure. At the same timere than a million people moved to other parts of the country. AlthoughIl population increased slightly, the increase was much less than theional average.'ontributing to discontent over uneven distribution of R&D fundsrowing frustration over a Middle West "brain drain." For instance,owa the two major universities estimate that from 55 to 75 percentthe graduates leave the state for their first jobs. The states in which"Big Ten" universities are located produce about 40 percent of allntists and engineers with advanced degrees, but this region receivesy a small fraction of federal R&D funds. To apply their training manythe scientists must migrate; their migration represents an economicto a region which yearly spends huge sums on higher education.'ome of the frustration felt in the Midwest was expressed recentlyPresident Harrington of the University of Wisconsin, who said:'Failure to provide for geographical spread of federal defense andse contracts has brought our nation face-to-face with a most seriousI of over-concentration:Over-concentration of our working scientists and engineers by region;Over-concentration of our industrial and defense strengths by region.If these tendencies continue in the award of federal research, devel-nent, and production contracts, we are on the road to manpoweros, economic chaos, social chaos, defense chaos."'he feelings expressed by President Harrington are not unrelated tossures now evident with respect to the proposed new 200-Bev ac-

rator (Science, 18 June, p. 1571). Major midwestern universities,e agreed to support whatever midwestern site appears to be most inrunning after initial screenings. If the region exerts its maximumential pressure, Washington will find it difficult to place the facilitywhere. Whatever the outcome, politics is destined to be a crucialor, and an important precedent will be established. The influence ofitical and geographical considerations on the allocation of researchds is certain to increase.-PHILIP H. ABELSON