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Jointly sponsored by The School of Medicine ofThe University of North Carolina at Chapel Hill and Charlotte AHEC

Offered atThe William and Ida Friday Center for Continuing Education

Chapel Hill, North Carolina

44TH ANNUALINTERNAL MEDICINECONFERENCE March 11-13, 2020

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Charlotte AHEC and The Department of Medicine of theUniversity of North Carolina at Chapel Hill School of Medicine Present:

Target AudienceThis conference is designed for internists, family physicians, generalists, advancedpractice providers and other health careproviders working in an adult primary caresetting.

Course Description The 44th Annual Internal Medicine Conferencewill update attendees on the most recentdevelopments in the diagnosis and management of medical disorders encounteredin primary care.

Conference FeaturesThis conference features cutting edge,evidence-based updates on common medicalconditions managed by primary careclinicians.

The information presented at this educationalactivity should improve your ability to:

Educational Objectives

➲ Discuss the latest cardiovascular trials andincorporate into current practiceDiscuss the pros/cons of the latesthypertension guidelines

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Practice the latest evidence-basedmanagement of diabetes

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Discuss safety management of opioids➲

Conference LocationThe conference will be held at the William andIda Friday Center for Continuing Education100 Friday Center DriveChapel Hill, NC 27599919-962-3009

Application for CME credit has been filed withthe American Academy of Family Physicians.Determination of credit is pending.

AAFP Credit

RegistrationAll registrants must complete the attachedregistration form or register online atwww.charlotteahec.org.

Accreditation StatementThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Atrium Health and The School of Medicine of The University ofNorth Carolina at Chapel Hill. Atrium Health is accredited by the ACCME to provide continuing medical education for physicians.

AccommodationsPlease contact the hotels directly to make reservations and identify yourself as an attendee at the 44th Annual Internal Medicine Conference. A block of rooms has been reserved at the following hotels:ALOFT – Special rate of $124 + tax per night. Please call 1.866.961.2993 to make yourreservation. This room block expires onFebruary 10, 2020.

Courtyard by Marriott – Special rate of $142+ tax per night. Please call 1.800.321.2211 tomake your reservation. This room blockexpires on February 10, 2020.

Sheraton Chapel Hill Hotel – Special rate of$129 + tax per night. Please call 1.800.325.3535to make your reservation. This room blockFebruary 11, 2020.

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REGISTRATIONPlease complete a separate registration form for each person. Registrations will not be processed unlessaccompanied by full payment (check, or credit card). You may register by:

• Completing on-line registration at: https://www.charlotteahec.org/continuing-professional-development/event.cfm?eventid=60588

• Mailing your form, along with a check to:

Charlotte AHEC Registrar PO Box 32861 Charlotte, NC 28232-2861

Check made payable to Charlotte AHEC

Please Print Legibly

Last Name: _______________________________ First Name: __________________________ MI: _________

Mailing Address: Please check appropriate box: ❑ Home ❑ Business

________________________________________________________________________________________________

Phone: ___________________________________ E-mail: _____________________________________________

City: _____________________________________ State: _________________ Zip Code: __________________

Credentials: Specialty: ________________________________________________________________________

Employer: ______________________________________________________________________________________

REGISTRATION FEES (please mark applicable fee)❑ 3 day - $450❑ Wednesday - $200❑ Thursday - $200❑ Friday - $200❑ Wednesday & Thursday - $350❑ Thursday & Friday - $350

The 44th Annual Internal Medicine ConferenceMarch 11-13, 2020

Event # 60588

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Credit Designation StatementAtrium Health designates this Live Activity for a maximum of 23.0 AMA PRA Category 1Credit(s)TM. Physicians should claim only thecredit commensurate with the extent of theirparticipation in this activity.Wednesday, March 11 – 8.0Thursday, March 12 – 8.0Friday, March 13 – 7.0The Charlotte Area Health Education Center(AHEC) designates this continuing education

Cancellation PolicyCancellations equal to or more than 14 business days prior to the event will receive 100% refund.Registrants cancelling between 13 - 2 business days prior to the event are refunded at 70% of the registration fee subject to a minimum $25 cancellation fee. No refunds or credits will be given for cancellations received less than 2 full business days prior to the event. Cancellations must be in writing (fax, email, or mail). Transfers/substitute(s) welcome (notify in advance of the event).

Disclaimer: By providing your email address and telephone number, you have granted permission for AHEC to contact you via the numbers and address indicated. Would you like your name to be removed from our mailing list? ❑ Yes ❑ No

By registering for the program, you authorize Charlotte AHEC to release your name, city and state to attending commercial supporters. Please contact the program support listed below if you have any questions or concerns.

program as fulfilling the requirement for2.3 Continuing Education Units (CEUs),representing 23.0 Contact Hours.

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NEPHROLOGY AND HYPERTENSION

1:30-1:35 Introduction Raven Voora, MD1:35-2:15 Hypertension Guidelines: Are They Realistic? Pro/Con Debate Alan L. Hinderliter, MD Raven Voora, MD2:15-2:40 What’s New in Diabetic Kidney Disease? Amy K. Mottl, MD, MPH2:40-3:00 Approach to Cystic Kidney Disease Emily H. Chang, MD3:00-3:20 OPEN PANEL DISCUSSION Nephrology and Hypertension Raven Voora, MD, Moderator Emily H. Chang, MD Alan L. Hinderliter, MD Amy K. Mottl, MD, MPH 3:20-3:50 Late Breaking Presentation (will address timely medical topic/research findings reported or published in early 2020)3:50-4:10 BREAK

10:45-11:15 Update on Osteoporosis: Do I Really Need to Write that Pre-Auth? Janet Rubin, MD11:15-11:40 Case-Based Endocrinology Pitfalls and Pearls Joshua M. Evron, MD11:40-12:00 OPEN PANEL DISCUSSION: Endocrinology John B. Buse, MD, PhD, Moderator Joshua M. Evron, MD Janet Rubin, MD12:00-1:30 LUNCH - Trillium Room OPTIONAL: 12:45-1:30: Lunch Time Update – Hematology/Oncology: Charlie the Lemur and Other Thrombosis/Anticoagulation Updates Stephan Moll, MD or 12:45-1:15: Group Walk to Meadowmont Village

4:10-4:15 Introduction Jan Busby-Whitehead, MD4:15-4:55 Hypertension Treatment as Primary Prevention for Mild Cognitive Impairment and Dementia Jeff D. Williamson, MD4:55-5:10 Statins for Primary Prevention of Cardiovascular Disease for Patients 65 and Older: How Old is Too Old? Thomas C. Keyserling, MD, MPH5:10-5:40 Update on Management of Subclinical Hypothyroidism Among Older Patients J. Marvin McBride, MD, MBA5:40-6:00 OPEN PANEL DISCUSSION Geriatrics Jan Busby-Whitehead, MD, Moderator Thomas C. Keyserling, MD, MPH J. Marvin McBride, MD, MBA Jeff D. Williamson, MD6:00-7:30 Reception and Entertainment with Musical Classical Trio at The Friday Center Guests Welcome

GERIATRICS

HEMATOLOGY/ONCOLOGY

8:00-8:05 Introduction Nigel S. Key, MB, ChB8:05-8:35 Update on Thrombocytopenia Alice Ma, MD8:35-9:00 An Optimistic Update on Sickle Cell Disease Jane A. Little, MD9:00-9:30 Updates on Multiple Myeloma, MGUS, and Other Plasma Cell Diseases Sascha A. Tuchman, MD9:30-9:50 OPEN PANEL DISCUSSION Hematology/Oncology Nigel S. Key, MB, ChB, Moderator Alice Ma, MD Jane A. Little, MD Sascha A. Tuchman, MD9:50-10:10 BREAK

FRIDAY, MARCH 13, 2020

CARDIOLOGY

10:10-10:15 Introduction Cody S. Deen, MD10:15-10:35 Improving the Evaluation of Syncope Anil K. Gehi, MD10:35-11:00 New Noninvasive Testing for CAD, CTA Fractional Flow Reserve (FFR) Joseph A. Sivak, MD11:00-11:25 Update on New HFrEF Therapies Mirnela Byku, MD, PhD11:25-11:50 Top Cardiovascular Trials for Internist, 2020 Cody S. Deen, MD11:50-12:10 OPEN PANEL DISCUSSION Cardiology Cody S. Deen, MD, Moderator Mirnela Byku, MD, PhD Anil K. Gehi MD Joseph A. Sivak, MD12:10-1:00 LUNCH - Trillium Room1:00-1:30 Case-based Medical Imaging Review Joseph M. Stavas, MD

Mini-Symposium on Opioid Management 1:30-2:00 Evidence for Effectiveness of Opiates for Pain --Taking a Step or Two Back Timothy S. Carey, MD, MPH2:00-2:40 Moving Beyond Opioid-Centered Pain Care: Evidence and Exit Strategies Erin E. Krebs, MD, MPH2:40-3:00 OPEN PANEL DISCUSSION Opioid Mini-Symposium Timothy S. Carey, MD, MPH Erin E. Krebs, MD, MPH3:00-3:15 BREAK

Mini-Symposium on Selected Hospital Medicine Topics3:15-3:20 Introduction David F. Hemsey, MD3:20-3:40 Inpatient Evaluation of Syncope Michael J. Craig, MD, MPH 3:40-4:00 Management of Low Risk Chest Pain Christopher A. Caulfield, MD 4:00-4:20 Inpatient Initiation of Medication Assisted Opiate Abuse Treatment Clare K. Mock, MD

WEDNESDAY, MARCH 11, 20208:15-8:30 Welcome and Announcements Conference Co-Directors Marco A. Alemán, MD Thomas C. Keyserling, MD, MPH Sarah E. Smithson, MD, MPH Director Emeritus Romulo E. Colindres, MD, MSPH

RHEUMATOLOGY, ALLERGY, AND IMMUNOLOGY

8:30-8:35 Introduction Beth L. Jonas, MD8:35-9:00 Update on Food Allergy in Adults Onyinye I. Iweala, MD, PhD9:00-9:25 Approach to the Patient with Suspected Lupus Saira Z. Sheikh, MD 9:25-9:50 Quick Cases: Common Rheumatologic Conditions E. Amanda Snyder, MD9:50-10:05 OPEN PANEL DISCUSSION: Rheumatology, Allergy, and Immunology Beth L. Jonas, MD, Moderator Onyinye I. Iweala, MD PhD Saira Z. Sheikh, MD E. Amanda Snyder, MD 10:05-10:25 BREAK

10:25-10:30 Introduction Darren A. DeWalt, MD, MPH10:30-11:10 Romulo E. Colindres Distinguished Lecture The USPSTF’s Prostate Cancer Screening Recommendation: Challenges with Weighing Benefits and Harms Alex H. Krist, MD, MPH11:10-11:35 Assessing Breast Cancer Risk and Medications to Reduce Risk H. Claire West, MD11:35-11:55 Advanced Care Planning Katherine Aragon, MD11:55-12:15 OPEN PANEL DISCUSSION: General Medicine and Clinical Epidemiology Darren A. DeWalt, MD, MPH, Moderator Katherine Aragon, MD Alex H. Krist, MD, MPH H. Claire West, MD12:15-l:45 LUNCH - Trillium Room OPTIONAL: 1:00-1:45: Lunch Time Update – New Options for Treatment-Resistant Depression: Ketamine Infusion, Intranasal Esketamine, and Transcranial Magnetic Stimulation Robert K. McClure, MD or 1:00-1:30: Group Walk to Meadowmont Village

GENERAL MEDICINE AND CLINICAL EPIDEMIOLOGY

INFECTIOUS DISEASES

1:45-1:50 Introduction David J. Weber, MD, MPH1:50-2:15 Update on Antibiotics Anne M. Lachiewicz, MD, MPH2:15-2:40 Pertussis, Measles, Rabies Oh My! Post Exposure Management Arlene C. Seña, MD, MPH

4:20-4:25 Introduction Shannon S. Carson, MD4:25-4:50 Vaping and E-Cigarette Related Acute Lung Injury M. Leigh Anne Daniels, MD, MPH4:50-5:15 Idiopathic Pulmonary Fibrosis – Early Diagnosis and Treatment Options Kunal P. Patel, MD, PhD5:15-5:40 New Medical Therapies for Cystic Fibrosis – Changing the Course of a Genetic Disease Jennifer L. Goralski, MD5:40-6:00 OPEN PANEL DISCUSSION: Pulmonary and Critical Care Medicine Shannon S. Carson, MD, Moderator M. Leigh Anne Daniels, MD, MPH Jennifer L. Goralski, MD Kunal P. Patel, MD, PhD

PULMONARY AND CRITICAL CARE MEDICINE

THURSDAY, MARCH 12, 2020

8:00-8:05 Introduction Animesh Jain, MD8:05-8:25 Update on Fatty Liver Disease Neil D. Shah, MD8:25-8:45 Current State of the Microbiome Sarah K. McGill, MD, Msc8:45-9:15 Update on Constipation for the PCP Yolanda V. Scarlett, MD9:15-9:35 Quick Cases: GI and Hepatology Animesh Jain MD & Panel9:35-9:50 OPEN PANEL DISCUSSION Gastroenterology and Hepatology Animesh Jain, MD, Moderator Sarah K. McGill, MD, Msc Yolanda V. Scarlett, MD Neil D. Shah, MD9:50-10:10 BREAK

GASTROENTEROLOGY AND HEPATOLOGY

ENDOCRINOLOGY

10:10-10:15 Introduction John B. Buse, MD, PhD10:15-10:45 Diabetes Update: Indications for and Cost of SGLT2 Inhibitors and GLP-1 Receptor Agonists and How to get Patients to Take Them John B. Buse, MD, PhD

2:40-3:05 Invasive Infections in Persons Who Inject Drugs Asher J. Schranz, MD3:05-3:25 OPEN PANEL DISCUSSION: Infectious Diseases David J. Weber, MD, Moderator Anne M. Lachiewicz, MD, MPH Asher J. Schranz, MD Arlene C. Seña, MD, MPH3:25-4:00 TIA: Top 10 Tips for Evaluation and Management in the Ambulatory Setting Ana C. Felix, MBBCh4:00-4:20 BREAK

UNC Department of Medicine FacultyCONFERENCE DIRECTOR EMERITUSRomulo E. Colindres, MD, MSPH - Professor ofMedicine, Division of Nephrology & Hypertension

CONFERENCE CO–DIRECTORSMarco A. Alemán, MD - Professor of Medicine,Division of General Medicine & Clinical EpidemiologyThomas C. Keyserling, MD, MPH - Professor ofMedicine, Division of General Medicine & ClinicalEpidemiologySarah E. Smithson, MD, MPH - Assistant Professor of Medicine, Division of General Medicine & Clinical Epidemiology

Guest FacultyErin E. Krebs, MD, MPH - Chief of General InternalMedicine, Minneapolis VA Health Care System, Professor of Medicine, University of Minnesota MedicalSchool Alex H. Krist, MD, MPH - Professor of Family Medicine;Chair, Ambulatory Care Outcomes Research Network,Department of Family Medicine and Population Health,Virginia Commonwealth University School of MedicineJoseph M. Stavas, MD - Professor of Radiology,Creighton University; Senior Vice President of ClinicalDevelopment, TwinCityBio/inRegenJeff D. Williamson, MD - Professor of Gerontology andGeriatric Medicine, Department of Medicine,Wake Forest School of Medicine

Katherine Aragon, MD - Assistant Professor of Medicine,Division of General Medicine & Clinical EpidemiologyJan Busby-Whitehead, MD - Professor of Medicine;Chief, Division of Geriatric Medicine; Director, Center forAging and HealthJohn B. Buse, MD, PhD - Verne S. Caviness DistinguishedProfessor of Medicine; Chief, Division of Endocrinology;Director, NC Translational and Clinical Sciences InstituteMirnela Byku, MD, PhD - Assistant Professor of Medicine, Division of CardiologyTimothy S. Carey, MD, MPH - Sarah Graham KenanProfessor of Medicine, Division of General Medicine &Clinical EpidemiologyShannon S. Carson, MD - Professor of Medicine; Chief,Division of Pulmonary Diseases & Critical Care MedicineChristopher A. Caulfield, MD - Assistant Professor ofMedicine, Division of Hospital Medicine; Medical Director,Observation UnitEmily H. Chang, MD - Assistant Professor of Medicine,Division of Nephrology & HypertensionMichael J. Craig, MD, MPH - Associate Professor ofMedicine, Division of Hospital Medicine; Associate Chief,Clinical Operations at Chapel HillM. Leigh Anne Daniels, MD, MPH - Clinical Instructorof Medicine, Division of Pulmonary Diseases & CriticalCare MedicineCody S. Deen, MD - Assistant Professor of Medicine,Division of CardiologyDarren A. DeWalt, MD, MPH - John Randolph andHelen Barnes Chambliss Distinguished Professor ofMedicine; Chief, Division of General Medicine &Clinical EpidemiologyJoshua M. Evron, MD - Assistant Professor of Medicine,Division of Endocrinology

Ana C. Felix, MBBCh - Assistant Professor of Medicine,Division of General Medicine & Clinical EpidemiologyAnil K. Gehi, MD - Sewell Family-McAllister DistinguishedProfessor of Medicine, Division of Cardiology: Director,Clinical Cardiac Electrophysiology ServiceJennifer L. Goralski, MD - Assistant Professor of Medicineand Pediatrics, Division of Pulmonary Diseases & CriticalCare MedicineDavid F. Hemsey, MD - Associate Professor of Medicine;Chief, Division of Hospital MedicineAlan L. Hinderliter, MD - Henry A. Foscue DistinguishedProfessor of Medicine, Division of CardiologyOnyinye I. Iweala MD, PhD - Assistant Professor ofMedicine, Division of Rheumatology, Allergy & ImmunologyAnimesh Jain, MD - Assistant Professor of Medicine,Division of Gastroenterology & HepatologyBeth L. Jonas, MD - Reeves Foundation Distinguished Professorof Medicine; Chief, Division of Rheumatology, Allergy &ImmunologyNigel S. Key, MB, ChB - Harold R. Roberts Professor ofMedicine, Division of Hematology/Oncology; Director,UNC Hemophilia and Thrombosis Center Anne M. Lachiewicz, MD, MPH - Assistant Professor ofMedicine, Division of Infectious DiseasesJane A. Little, MD - Professor of Medicine, Division ofHematology/Oncology; Director, UNC Comprehensive SickleCell Disease ProgramAlice D. Ma, MD - The Medical Alumni Loyalty FundDistinguished Teaching Professor, Division of Hematology/OncologyJ. Marvin McBride, MD, MBA - Assistant Professor of Medicine,Division of Geriatric MedicineSarah K. McGill, MD, Msc - Assistant Professor of Medicine,Division of Gastroenterology & HepatologyClare K. Mock, MD - Assistant Professor of Medicine,Division of Hospital Medicine; Medical Director, HillsboroughHospitalStephan Moll, MD - Professor of Medicine, Division ofHematology/OncologyAmy K. Mottl, MD, MPH - Associate Professor of Medicine,Division of Nephrology & HypertensionKunal P. Patel, MD, PhD - Assistant Professor of Medicine,Division of Pulmonary Diseases & Critical Care MedicineJanet Rubin, MD - Sarah Graham Kenan DistinguishedProfessor of Medicine, Division of Endocrinology; Vice Chairfor Research, Department of MedicineYolanda V. Scarlett, MD - Assistant Professor of Medicine,Division of Gastroenterology & HepatologyAsher J. Schranz, MD - Assistant Professor of Medicine,Division of Infectious DiseasesArlene C. Seña, MD, MPH - Associate Professor of Medicine,Division of Infectious Diseases; Medical Director,Durham County Health DepartmentNeil D. Shah, MD - Assistant Professor of Medicine,Division of Gastroenterology & HepatologySaira Z. Sheikh, MD - Assistant Professor of Medicine,Division of Rheumatology, Allergy & Immunology: Director,Clinical Trials Program, UNC Thurston Arthritis ResearchCenter and UNC Rheumatology Lupus ClinicJoseph A. Sivak, MD - Assistant Professor of Medicine,Division of CardiologyE. Amanda Snyder, MD - Assistant Professor of Medicine,Division of Rheumatology, Allergy & ImmunologySascha A. Tuchman, MD - Associate Professor of Medicine,Division of Hematology/Oncology; Director, UNC MultipleMyeloma and Amyloidosis Program

Robert K. McClure, MD - Assistant Professor ofPsychiatry, Department of Psychiatry

Other UNC Department Faculty

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Raven Voora, MD - Assistant Professor of Medicine,Division of Nephrology & HypertensionDavid J. Weber, MD, MPH - Professor of Medicine,Pediatrics, and Epidemiology, Schools of Medicine andPublic Health, Division of Infectious Disease; AssociateChief Medical Officer, UNC Health CareH. Claire West, MD - Associate Professor of Medicine,Division of General Medicine & Clinical Epidemiology

4:20-4:40 OPEN PANEL DISCUSSION Hospitalist Mini-Symposium David F. Hemsey, MD, Moderator Christopher A. Caulfield, MD Michael J. Craig, MD, MPH Clare K. Mock, MD

Conference Adjourns until March 10-12, 2021