30 speed & flexibility-the adda system nick levitt - apricot designs
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Transcript of 30 speed & flexibility-the adda system nick levitt - apricot designs
The ADDA AutosamplerThe ADDA Autosampler
Designs that make sense 3
• Online SPE in 8 seconds
• Injection to injection timing
• One line equilibrates while the other performs
• Washing (internal and external rinse) for low carryover
What is flexible?What is flexible?
Designs that make sense 4
• Some Buddhist monks
• Fold-up Cars (2013)…
The ADDA AutosamplerThe ADDA Autosampler
Designs that make sense 5
• Automatically switch between:• High-speed trap & elute
mode• Full gradient mode.
• Combine high-speed screening with in-depth sample analysis• Separating interferences• Quan/Qual workflows• Flexibility for the discovery
lab
IntegratedIntegrated• Software designed by Sound Analytics LLC• Fully integrated with AB SCIEX mass
spectrometers
Designs that make sense 6
Dual stream LC-20AD (Shimadzu) gradient trace. ADDA 75s injection to injection, flow rate = 0.5ml/min. Baseline separation of five standard CYP450 inhibition metabolites (8 samples, 10 minutes)
1A2
2D6
3A4
2C9
2C8
FlexibleFlexible
8Designs that make sense
The ADDA Dual Arm Autosampling System.
SpeedFlexibility
From Apricot Designs.
For more information, contact:
Nick Levitt [email protected] Lawton [email protected]
Designs that make sense 9
• The speed of 2 high speed robotic arms• Online SPE LC/MS at 8s /sample with wash.• A software system to control all valves, pumps, and the MS.
The ADDA Autosampling SystemThe ADDA Autosampling System