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Name Other Names MW Structure Distribution Function CD1d CD1.1/1.2, Ly-38 43- 49kD IgSF leukocytes, intestinal epith Ag presentation, mucosal immunity, with beta2m, ligand for NKT cells CD2 LFA-2, Ly- 37, SRBC-R 45- 58kD IgSF thymocytes, T, NK, B, pre-B, myeloid, erythrocytes adhesion, T activation, CD48 receptor CD3d T3d 20kD IgSF T, thymocyte subset, NKT TCR subunit, TCR expression & signaling CD3e T3e 20kD IgSF T, thymocyte subset, NKT TCR subunit, TCR expression & signaling CD3g T3g 25kD IgSF T, thymocyte subset, NKT TCR subunit, TCR expression & signaling CD4 Ly-4, L3T4 55kD IgSF thymocyte subset, T subset, DC TCR coreceptor, thymic differentiation, T activation, MHC class II receptor CD5 Ly-1 67kD SRCRSF thymocytes, T, B subset (B1) T activation, T- B interaction, CD72 receptor CD6 T12 100- 130kD SRCRSF thymocytes, T, neurons, not on B T differentiation & costimulation, CD166 receptor

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NameOther

Names MW Structure Distribution Function

CD1dCD1.1/1.2,

Ly-3843-

49kD IgSF

leukocytes,intestinal

epith

Agpresentation,

mucosalimmunity, withbeta2m, ligandfor NKT cells

CD2LFA-2, Ly-

37, SRBC-R45-

58kD IgSF

thymocytes,T, NK, B,

pre-B,myeloid,

erythrocytes

adhesion, Tactivation,

CD48 receptor

CD3d T3d 20kD IgSFT, thymocytesubset, NKT

TCR subunit,TCR

expression &signaling

CD3e T3e 20kD IgSFT, thymocytesubset, NKT

TCR subunit,TCR

expression &signaling

CD3g T3g 25kD IgSFT, thymocytesubset, NKT

TCR subunit,TCR

expression &signaling

CD4 Ly-4, L3T4 55kD IgSF

thymocytesubset, T

subset, DC

TCRcoreceptor,

thymicdifferentiation,T activation,MHC class II

receptor

CD5 Ly-1 67kD SRCRSF

thymocytes,T, B subset

(B1)

T activation, T-B interaction,

CD72 receptor

CD6 T12100-

130kD SRCRSF

thymocytes,T, neurons,

not on B

T differentiation& costimulation,CD166 receptor

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CD7 40kD IgSF

human earlyT marker,

CD7KO hasnormal

phenotype

CD8a Ly-232-

34kD IgSF

thymocytesubset, T

subset , DCsubset, notfresh NK

TCRcoreceptor,MHC class Ireceptor, T

differentiation,homodimer orheterodimerwith CD8b

CD8b Ly-3 30kD IgSF

thymocytesubset, T

subset, notfresh NK

TCRcoreceptor,MHC class Ireceptor, T

differentiation,heterodimerwith CD8a

CD9 p2424-

27kD TM4SF

myeloid,platelets,Tact, Bsubset

cell adhesion,migration, T

costimulation

CD10CALLA,

NEP, Mme 100kD type II TM

B precursors,fibroblasts,BM stromal

cells

zinc-bindingmetalloproteinase,

neutralendopeptidaseectoenzyme, Bdevelopment

CD11a

integrinalphaL, Ly-

15, Itgal 80kD IntgF

T, B, NK,gran, mono,

mac, DC,thymocytes

CD11a / CD18(LFA-1)

receptor forICAM-1 and

ICAM-2,intercellularadhesion, T

costimulation

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CD11b

Mac-1,integrinalphaM,

Itgam, CR3 170kD IntgF

myeloid, NK,Tact, Bsubset

CD11b / CD18receptor forCD54 and

CD102,adhesion to

ECM,fibrinogen, &complement

iC3b

CD11c

p150,integrinalphaX,

Itgax, CR4 150kD IntgFDC, myeloid,NK, T subset

CD11c / CD18receptor forfibrinogen &

iC3b, adhesion

CD13Aminopeptidase

N, Lap1 150kDType II

TMmyeloid,

endoth, DC

zinc-bindingmetalloproteinase,

antigenprocessing

CD14 LPS-R, Mo253-

55kDGPI-

linked mac, granlow

receptor forLPS/LBP, LPS

recognition

CD15 Lewis-X CHOtransient in

brain

fucosyltransferase

(Fut4)

CD16FcgammaRIII,Ly-17, Fcgr3

50-60kD IgSF

NK,neutrophils,mast cells,

mac

Fcgamma lowaffinity

receptor,phagocytosis,

ADCC, NKactivation

CD18Integrin

beta2, Itgb290-

95kD IntgF leukocyteswith CD11a, b

and c, adhesion

CD19 B4 95kD IgSF

B, FDC, goodB lineage

marker, notplasma cells

with CD21 &CD81, BCR

coreceptor, Bactivation /

differentiation

CD20Ly-44, B1,

Ms4a233-

37kD TM4SF B, T subsetB differentiation

/ activation

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CD21 CR2, CR1 150kD CCRSF B, DC

CD21 / CD35other variantsof CR2 gene,complement

C3d receptor,with CD19 &CD81, BCRcoreceptor

CD22Lyb-8,

Siglec-2140-

160kDIgSF /

sialoadhesins B

adhesion, B-mono & B-T

interactions, Bactivation, BM

homingreceptor forIgD+ B cells,

CD75 counter-receptor

CD23

FcepsilonRII,Ly-42,Fcer1a

45-49kD

C-typelectin

B, mono,mac, gran,platelets,

FDC, not B1cells

CD19/CD21/CD81receptor, lowaffinity IgER,

signaling

CD24aHSA, Ly-52,

Nectadrin35-

52kDGPI-

linked

B, gran,mono, mac,

Tact,erythrocytes,

neurons

severalisoforms, B

differentiation &proliferation,adhesion, T

costimulation,CD62Preceptor

CD25Ly-43, p55,IL2Ralpha 55kD

Type ITM

pre-B, pre-T,Tact, Bact,DC subset,mono, mac

low affinity IL-2binding, with IL-

2Rbeta &gamma formsIL-2 receptorhigh affinity,also soluble

form

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CD26DPP4,THAM 110kD

Type IITM

thymocytesubset, Tact,B, NK, epith

dipeptidylpeptidase

ectoenzyme,activation,adhesion

CD27 T14, Tnfrsf7 45kD TNFRSF

medullarythymocytes,

T, NK, Bsubset

CD70 receptor,T costimulation

CD28 Tp44 45kD IgSF

T,thymocytes,

NK

CD80 (B7-1) &B7-2 (CD86)receptor, T

costimulation

CD29

Integrinbeta1, gpIIa,

Itgb1 130kD IntgF

leukocytes,fibroblasts,

endoth, epith

with CD49a-f(VLA-1-6), with

CD51(alphavbeta1),CD29/CD49a (VLA-1) receptor

for VCAM-1,MAdCAM-1 &ECM, VLAb,

adhesion,embryonic

development

CD30 Ki-1, Tnfrsf8105-

120kD TNFRSF Bact, Tact

CD153receptor,

lymphocyteproliferation,apoptosis,peripheraltolerance

CD31PECAM-1,

pgIIa130-

140kD IgSF

platelets,gran, endoth,

DC, monosubset, Tsubset, B

subset, LAK

multipleisoforms, CD38

receptor,signaling,

platelet-endothadhesion

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CD32

FcgammaRII,Ly-17,Fcgr2b

40-60kD IgSF

mono, mac,gran, B, Tact,

not NK

low affinity Fcreceptor foraggregatedIg/immunecomplexes,

ADCC

CD33Siglec-3,

gp67 67kDIgSF,

sialoadhesins

myeloidprogenitors;

gran

possible role inhematopoiesis,binds sialic-acid

CD34 Mucosialin90-

120kDSialomucin

family

hematopoieticprecursors,

capillaryendoth, BM

stroma, mastcells

CD62Lreceptor,adhesion

CD35 Cr1, Cr2 190kD SRCRSFB, granact,

FDC

CD21 & CD35alternative

splice variantsof Cr2 gene,binds C3b &

C4b, adhesion,phagocytosis

CD36

FAT, fattyacid

translocase 88kD

platelets,adipocytes,mono, mac,

endoth,erythrocyte

oxidized LDLreceptor

CD37 TM4SF

mRNA:lymphoid,myeloid T-B interaction

CD38Cd38-rs1,

T10 42kDType II

TM

B, marginalzone B

(high), Tact,thymocyte

subset,subsets inyolk sac, infetal liver, in

BM

B activation,CD31 receptor,

ectoenzyme,ADP-ribosyl

cyclase/hydrolase

CD39 Entpd170-

100kD

lymphocyteact,microglia,

endoth

ecto-nucleosidetrisphosphate

diphosphohydrolase

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CD40

gp39receptor,Tnfrsf5

45-50kD TNFRSF

B, mono,mac, T

subset, DC,endoth,

thymic epith,induced on

cardiacmyocytes

CD154receptor, T-Binteraction, Bcostimulationand survival,

isotype-switching

CD41

gpIIb,Itga2b,CD41b

110-125kD IntgF

platelets,megakaryocytes

with CD61forms

GPIIb/IIIa,binds

fibrinogen,fibronectin,

vWF &thrombospondin,

plateletactivation,

aggregation

CD42 Gp9, GPIX 20kD LRRFplatelets,

megakaryocytes

plateletactivation,

aggregation

CD43

Leukosialin,Ly-48, Spn,sialophorin

115 &135kD

Type ITM

T, Tact, earlyB, B subset,plateletslow,not resting B,

not DC

isoforms,signaling,CD54R, Bsurvival,adhesion

CD44

Pgp-1, Ly-24,

HERMES

80-95&

130kD

broad,memory T,

not platelets,or

hepatocytes

bindshyaluronic acid,

leukocyteadhesion/homing,

T activation,tumor

metastasis

CD44Rvariants of

CD44restricted &

varied

adhesion,metastasis,receptor forHyaluronate

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CD45LCA, Ly-5,

Ptprc180-

240kD

PTPRfamily,ASV

leukocytes,not mature

erythrocytes

tyrosinephosphatase,

leukocytedifferentiation /activation, pan-

leukocytemarker

CD45.1

Ly-5.2strains: SJL,DA, STS/A,

RIII

CD45.2

Ly-5.1strains:BALB/c,

C3H,C57BL/6,DBA/1,

DBA/2, AKR,A, 129

CD45R/CT1 CT1 CHOcytotoxic

Tact

CD45R B220 220kD

B, NKprogenitors,LAK, Tact

CD45RAexon Aisoform

CD45RB200-

240kDexon Bisoform

T subset, B,mono, mac

CD45RC200-

240kDexon Cisoform T subset, B

CD45RO 180kD

isoformnot exonsA, B, or C

Tact, Bact,DC subset

CD46

MCP,membrane

cofactorprotein CRRSF broad

complementregulation, rolein fertilization

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CD47 IAP, Itgp 50kD IgSF

hematopoieticcells, epith,

endoth,fibroblasts,

platelets

with beta3integrins,leukocyteadhesion,migration,activation,

extravasation ofPMN, bindsSIRPalpha

CD48

Blast-1,BCM-1,Sgp-60 45kD

IgSF,GPI-

linked

broad onlymphocytes,

notfibroblasts

adhesion, Tcostimulation,CD2 and Ly-9

receptor

CD49a

VLA-1,Integrinalpha1,Itga1 180kD IntgF Tact, endoth

adhesion,CD49a / CD29binds collagen

& laminin

CD49b

VLA-2,Integrinalpha2,Itga2 165kD IntgF

platelets, Tsubset,

megakaryocytes,NK subset

adhesion,CD49b / CD29binds collagen

& laminin

CD49c

VLA-3,Integrinalpha3,Itga3 125kD IntgF

B subset,Tlow

CD49c/CD29binds laminin,

fibronectin,collagen

CD49d

VLA-4,Integrinalpha4,Itga4 150kD IntgF T, B, mono

CD49d / CD29binds

fibronectin,VCAM-1, withbeta7 formsLPAM-1 &binds to

MAdCAM-1,homingreceptor

CD49e

VLA-5,Integrinalpha5,Itga5 135kD IntgF

thymocytes,Tact

adhesion,CD49e / CD29

bindsfibronectin

CD49f

VLA-6,Integrinalpha6,Itga6 120kD IntgF

memory T,thymocytes,

platelets

adhesion,CD49f / CD29binds laminin

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CD50Icam5, Ticn,Telencephalin130kD IgSF

memory T,thymocytes,

platelets

adhesion,CD49f / CD29binds laminin

CD51

VitronectinR,Integrinalphav,Itgav

125,24kD IntgF

platelets,megakaryocytes,

endoth,osteoblasts,melanoma

adhesion,CD51 / CD61

bindsvitronectin, von

Willebrandfactor,

fibrinogen &thrombospondin

CD52

CAMPATH-1, MB7,CLS1 12kD

GPI-linked

maturelymphocytes

CD53 OX-4435-

42kD TM4SF

leukocytes,DC,

osteoblasts,osteoclasts signaling

CD54ICAM-1, Ly-

4785-

110kD IgSF

endoth,mono, restinglymph (high

on activation)

CD11a / CD18(LFA-1), CD11b/ CD18 (Mac-1)

& CD43receptor,

adhesion, Tcostimulation

CD55

DecayAccelerating

Factor60-

70kD CCRSF

broad,induced inuterus byestrogen

similar to Crry,protection from

autologouscomplement

attack

CD56 NCAM20-

185kD IgSF

neural tissue,multipleisoforms

adhesion,neuron

development,skeletal

myogenesis

CD57 B3GAT1Glucuronsyl-transferase P

CD58(H) LFA-3

not defined inmouse

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CD59

Protectin,MAC-

inhibitor 19kDGPI-

linked broad

bindscomplement C8

& C9, blocksmembrane

attack complexassembly

CD60(H) CHO

not defined inmouse

CD61

GPIIIa,Integrin

beta3, Itgb3 105kD IntgF

platelets,megakaryocytes,mac, endoth

CD41 / CD61or CD51 /

CD61complexes

adhere to ECM

CD62E

E-selectin,ELAM-1,Sele 97

107-115kD Selectin endoth

sialyl-Lewis xreceptor,leukocyterolling &

migration,tumor

metastasis

CD62L

L-selectin,LECAM-1,

sell74 &95kD Selectin

B, T, mono,gran, NK,

thymocytes

CD34,GlyCAM, &MAdCAM-1

receptor,lymphocyte

homing,leukocyte

tethering &rolling

CD62PP-selectin,

Selp 140kD Selectinplateletsact,

endoth

CD162 & sialylLewisX

receptor,adhesion,neutrophil

rolling, platelet-neutrophil &

platelet-monointeractions,

binds to CD24

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CD63 MLA1 53kD TM4SFplateletsact,mono, mac

activatedplateletsmarker,

lysosomalmembrane

protein,translocates tosurface upon

activation,melanomaassociated

antigen

CD64 FcgammaRI 72kD IgSFmono, mac,DC, granact

high affinity IgGreceptor,

phagocytosis,trypsin-

sensitive,ADCC

CD65(H)

not defined inmouse

CD66aCeacam1,

C-Cam

IgSF,CEA

family

colon, liver,hematopoietic

tissues

cell-cellinteraction,

hepatitis virusreceptor

CD68Macrosialin,

gp11087-

115kD Sialomucin

predominantlyintracellular,tissue mac,

DClow

lysosomalassociated

protein

CD69

ActivationInducer

Molecule,VEA

35-39kD

C-typelectin

Tact, Bact,NKact,

granact,thymocytes,

platelets

activation, earlyactivation

marker

CD70Ki-24,Tnfsf7

50, 70,90,

160kD TNFSF

Bact, Tact,cardiac

myocytes

CD27 receptor,T & B

costimulation

CD71 T9, Trfr 95kD

Type IITM,

dimer

proliferatingcells,

reticulocytes,erythroid

precursors

transferrinreceptor, ironuptake, cellactivation

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CD72 Lyb-240-

45kD

C-typelectin,

homodimer

B, FDC, Tsubset,

polymorphicextracellular

portion

CD5 & CD100receptor, B

costimulation

CD73 Nt5e 69kDGPI-

linked

ecto-5’-nucleotidase, Tcostimulation,

adhesion

CD74

Ii, Ia-invariant

chain33-

43kDType II

TMB, mac,mono

MHC class IItraffic &function,antigen

presentation

CD75

BM homingof

recirculatingB cells, CD22

counter-receptor

CD77(H)

not defined inmouse

CD79aIga, mb-1,

Ly-5433 &45kD IgSF B

BCR subunit,BCR

expression &signaling

CD79b Igb, B29 37kD IgSF B

BCR subunit,BCR

expression &signaling

CD80B7, B7-1,

Ly-53 60kD IgSF

Bact, Tact,mono, mac,

DC,pancreaticbeta cells

CD28 & CD152receptor,

costimulation,T-B interaction

CD81 TAPA-1 26kD TM4SF

T, B, NK,thymocytes,DC, endoth,fibroblast,

neuroblastomas,melanomas

with CD19 &CD21,

signaling, Tcostimulation

CD82 KAI1, C3350-

53kDTM4SF,

ASV

Tact, mRNA:spleen,kidney

inhibits tumorcell mobility

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CD83 43kD

IgSF,Siglecfamily

DC, Tact,mRNA:

spleen &brain

regulation of Tresponse, bindsto a ligand on B

cells

CD84 IgSF

B, mac,mRNA:

hematopoietictissue

CD85MHC class Irecognition

CD86B70, B7-2,

Ly-58 80kD IgSFmono, Bact,

Tact, DC

CD28/CD152receptor, T

costimulation,T-B interaction

CD87UPA-R,Plaur

GPI-linked

mRNA:muPAR1

luminal epith ofgastric mucosa,muPAR2 basal

epith, PAR2secreted uPA

binding protein

CD88 C5aR, C5r1 40kD TM7SF

gran,neurons,

astrocytes,microglia

C5a receptor,granulocyteactivation,

neurodegeneration

CD89FcalphaR,

IgA receptor55-

75kD IgSF

mono, mac,neutrophils,B subset, T

subset

phagocytosis,degranulation,

respiratoryburst

CD90 Thy-1 18kD

IgSF,GPI-

linked

thymocytes,T,

hematopoieticsubset,

neurons, notB

hematopoieticstem cell &

neurondifferentiation,

T activation

CD90.1

thy1a(thy1.1)strains: AKR

& RF

CD90.2

thy1b(thy1.2)all otherstrains

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CD91 lrp1, A2mr 600kD

LDLreceptorfamily

mono, mac,neurons,

liver,fibroblasts

receptor for a-2-

macroglobulin,LDL, HSPgp96,apolipoprotein,

lipoproteinmetabolism

CD92(H)

not defined inmouse

CD93

AA4.1antigen,C1qRp,early Blineagemarker,

Ly68130-

140kDC-typelectin

hematopoieticprogenitormarker for

early B cells,endo,

megakaryoblasts,platelets

phagocyticcomplementC1q receptor

CD94 KP43, klrd1 43kDC-typelectin NK, T subset

with NKG2,inhibits NK

function

CD95 Apo-1, Fas 35kD TNFRSFthymocytes,

lymphocytesact

CD95L(CD178)receptor,apoptosisinduction,

immune systemregulation, lpr

mutation

CD96

TACTILE, Tcell

ACTivationIncreased

LateExpression 160kD IgSF

mRNA:spleen,

mammarygland

adhesion ofactivated T &

NK

CD97TM7LN1

TM7Slymphoid,myeloid CD55 receptor

CD98 4F2, Ly-1080,

40kD

thymocytes,lymphocytes,

mono, BMcell activation,calcium flux

CD99 Pilr-1, D4

CD100Sema4d,

semaphorinH 150kD IgSF

mRNA:lymphoid &

nervoustissues

CD72 receptor,role in immune

& nervoussystems

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CD101 IgSF3 IgSF

role insusceptibility totype I diabetes

CD102ICAM-2, Ly-

6055-

65kD IgSF

lymphocytes,mono,

platelets,endoth

binds CD11a /CD18 (LFA-1),costimulation

CD103

HML-1,alphaIEL,

alphaEintegrin,

Itgae 150kD IntgF

intraepitheliallymphocytes,

BM mast,lymphocytesact

with integrinbeta7, binds E-

cadherin,lymphocyte

homing

CD104

beta4integrin,

Itgb4 220kD IntgF

epith, endoth,immature

thymocytes,Schwann

cells, tumorcells,

keratinocytes

with CD49f, celladhesion /migration,

differentiation,tumor

metastasis,a6b4 is tumorassociated Ag

Tsp-180

CD105Endoglin,

Eng 95kD

endoth, BMcell subset,

macact

response toTGF-beta1,

ligand for TGF-beta, adhesion

CD106 VCAM-1 110kD IgSF

endothact,FDC, BMmyeloid

CD49d / CD29receptor,

adhesion /migration,

costimulation

CD107a LAMP-1 120kD

plateletsact,Tact,

endothactadhesion,metastasis

CD107b LAMP-2 110kD

plateletsact,Tact,

endothactadhesion,metastasis

CD108 Sema7a 80kD

IgSF,GPI-

linked

mRNA:nervous

system(high),immunesystem

CD109Gov plateletalloantigen

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CD110TPO-R, c-

mpl82-

84kD CRSFmegakaryocytes,

platelets

thrombopoietinreceptor,

megakaryocytedifferentiation

CD111

PRR1,Nectin-1,

Pvrl64-

72kDIgSF,ASV

fibroblasts,epithelium,

neurons

polio virusreceptor-related

protein1,mediates entry

of herpessimplex virus(HSV) strains

CD112PRR2, Pvs,

Nectin-264-

72kDIgSF,ASV

mRNA: brain,spinal cord,

spleen,kidney, heart,

liver

intercellularadhesion, not a

receptor forpoliovirus

CD113PVRL3,Nectin3 100kD

Ig-like,ASV broad, epith

adhesionmolecule,

interacts withafadin

CD114G-CSFR,

Csfgr, Csf3r95,

139kD CRSF

progenitor &mature

neutrophils,endoth,

placenta,some

myeloidleukemia

myeloidproliferation &differentiation

CD115M-CSFR, c-fms, Csf1r 150kD RTKF

monocyticprogenitors,osteoclasts

M-CSFreceptor,

monocyticlineage

proliferation/differentiation,

role indifferentiationof osteoclasts

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CD116 GM-Csf2ra70-

85kD CRSFmono, gran,DC, endoth

low affinity GM-CSF receptor,with commonbeta AIC2Bform high

affinityreceptor,myeloid

proliferation,differentiation

CD117c-kit, Steel

factor 145kDIgSF,RTKF

hematopoieticstem &

progenitors,neural crest-

derivedmelanocytes,

primordialgerm cells,mast cells

Stem CellFactor receptor,hematopoietic

progenitordevelopment &differentiation,dominant white

spotting (w)mutation

CD118 LIFR 190kD

Type Icytokinereceptorfamily,ASV

placenta,liver, kidney,heart, lung,brain epith

membrane-bound involved

in signaltransduction,soluble form

inhibits activityof LIF

CD119IFNgammaR,

ifgr1, Ifngr90-

100kD

mac, mono,B, T, NK,

neutrophils,endoth

Interferon-gamma

receptor alphachain, with

IFNgamma AF-1, host

defense, highaffinity

IFNgammabinding

CD120a TNFR1, p5550-

60kD TNFRSF broad

TNF receptor,binds both

TNFalpha &TNFbeta,apoptosis

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CD120b TNFR2, p7575-

85kD TNFRSF broad

TNF receptor,high affinitybinding to

TNFalpha &TNFbeta,apoptosis

CD121a IL-1R type I 80kD IgSF

broadlow,fibroblasts, T,

brain,pancreas,

cardiacendoth, epith,

developingoocytes

Type I IL-1R,binds IL-1alpha& IL-1beta, IL-1

signaling

CD121bIL-1R, type

II 68kD IgSF

B, mac,mono, T

subset (Th2),epidermis,

dermis,vaginal basalepith, brain

Type II IL-1R,binds IL-1alpha

& IL-1beta, adecoy receptor

CD122IL-2Rbeta,

p70 75kD CRSFNK, T, B,

mono

IL-2R & IL-15Rbeta chain,signaling, with

CD25 & CD132form high

affinity IL-2R,lymphocyte

development

CD123 IL-3Ralpha 70kD CRSF

lymphocytesubset,

basophils,hematopoieticprogenitors,

mac, DC,megakaryocytes

IL-3R alphachain, low

affinity bindingto IL-3, with

CDw131 formhigh affinity IL3

binding

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CD124 IL-4Ralpha 140kD CRSF

lymphocyteslow,mono,

hematopoieticprecursors,fibroblast,

epith

IL-4Ralphachain, with

CD132 or IL-13Ralphachain, with

CD132 formshigh affinity IL-4R, T growth &differentiation,soluble form

CD125 IL-5Ralpha 60kD CRSFeosinophils,basophils

IL-15Ralphachain, with

CDw131 for lowaffinity IL-5

binding, withbeta subunit forhigh affinity IL-

15 binding

CD126 IL-6Ralpha 80kDIgSF,CRSF

Bact, plasmacells, most

leukocyteslow,fibroblasts

IL-6Ralphasubunit, lowaffinity IL-6

binding, withCD130 for high

affinity IL-6binding, soluble

form

CD127 IL-7Ralpha65-

75kD CRSF pro-B, T

IL-7Ralphachain, with

CD132 for highaffinity IL-7

binding, T & Bdevelopment

CD128see CD181and CD182

CD130IL-6Rbeta,

gp130 130kD CRSF

broad in adult& embryonic

cells

Common betachain of IL-6R,IL-11R, LIFR,

OSMR

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CD131

IL-3R,AIC2B/A,common

beta,Csf2rb1,Csf2rb2

95-120kD CRSF

mono, gran,early B

2 genes inmouse,

signaling, withalpha subunitsof IL-3, IL-5,

GM-CSFreceptors

CD132

IL-2RCommon

beta 64kD CRSF

T, B, NK,mono, gran,

DC

Subunit of IL-2,IL-4, IL-7, IL-13, & IL-15R,

signaling,mutation: X-linked SCID

CD133Prominin-1,

AC133115-

120kDTM5

glycoprotein

primitive cellslike

hematopoieticprogenitors,

neural,endoth stemcells, retina,

retinoblastoma,developing

epith (apicalsurface) unknown

CD134OX-40, Ly-70, Txgp1

48-50kD TNFRSF Tact

OX-40Lreceptor,

apoptosis, Tactivation /

differentiation

CD135

Flt3/Flk2,EMS-like tyr

kinase 3130-

150kDRTK

family

hematopoieticprogenitors:myeloid &primitive Bprogenitors

binds FLT3ligand, myeloid

& lymphoiddevelopment,

expandshematopoieticprogenitors &

DC

CD136STK, Mst1r,

RON 180kDRTK

familyhematopoietic

cells

macrophagestimulatory 1

receptor

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CD1374-1BB,Tnfrsf9 30kD TNFRSF Tact

T costimulation,binds to 4-

1BBL,fibronectin,vitronectin,

laminin,collagen VI

CD138syndecan-1,

Sdc180-

150kD Syndecan

epith, plasmacells, pre-B,

neurons

receptor forECM, cell

morphology, Bdifferentiation

CD139(H)

not defined inmouse

CD140a

PDGFreceptor

alpha 180kDRTK

family

fibroblasts,smooth

muscle, glialcells,

chondrocytes

PDGFRaabinds PDGFAA, AB, BB,PDGFRab

binds AB, BB,PDGFRbb

binds PDGFBB,embryonic

development,signaling

CD140b

PDGFreceptor

beta 180kDRTK

family

fibroblasts,smooth

muscle, glialcells,

chondrocytes

see CD140a forligands,signaling

CD141 Thrombomodulin100kDC-typelectin

mono,neutrophils,

endoth,smoothmuscle

initiation ofprotein C

anticoagulantpathway

CD142

TissueFactor,

factorIII, F3 45kDmRNA:broad

binds clottingfactor VIIa,embryonic

development

CD143 ACE 170kD

endoth,epith,

neuron,fibroblasts,

macact

peptidyl-peptidase,angiotensinconverting

enzyme

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CD144Cadherin5,VECadherin 130kD Cadherins endoth

adhesion,intercellularinteraction

CD146MUC18, S-

endo, mcom IgSF

embryonictissue,

mammarytumors

cell adhesionduring

development

CD147Neurothelin,basigin, Bsg IgSF

leukocytesact,erythrocytes,

platelets,endoth

adhesion,blood-brain

barrier

CD148HPTP-eta,M4, M56

240-260kD

mRNA:broad, high inbrain, kidney

tyrosinephosphatase R

Type III

CD150SLAM, IPO-

3 75kD IgSF

T, B,maintained

on Th1

costimulation,proliferation, Ig

production

CD151PETA-3,SFA-1 32kD TM4SF

endoth,megakaryocytes,

plateletsadhesion,signaling

CD152CTLA-4, Ly-

56 33kD IgSF Tact

CD80, CD86receptor,

negative Tstimulation

CD153CD30L,Tnfsf8 40kD TNFSF

Tact, macact,neutrophil, B,induced on

cardiacmyocyte

CD30 receptor,T costimulation

CD154

CD40L,gp39, Ly-62,

Tnfsf532-

39kD TNFSF

transiently onTact, Bsubset

(intracellular),platelets

CD40 receptor,B & DC

costimulation, Tactivation

CD155 PVR80-

90kD IgSF mono, macPolio virusreceptor

CD156aADAM8,

MS2 69kDType I

TMneutrophils,

mono

metalloprotease,leukocyte

extravasation

CD156bTACE/

ADAM 17 100kD broad

zincmetalloprotease,TNF converting

enzyme

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CD156c

ADAM10,kuz,

kuzbanian,Madm 60kD

PeptidaseM12Bfamily

neuralprecursors,fibroblasts

proteolyticcleavage ofcell-surfacemoleculesincluding

Notch, TNF-alpha, APP &

ephrin-A2

CD157BST-1, Ly-

65, Bp338-

48kDGPI-

linked

gran, mono,early B, T

subset, BMstroma

ADP-ribosyl-cyclic ADP-

ribosehydrolase, pre-

B growthCD158

(H) KIRnot defined in

mouse

CD159aNKG2A,

Klrc1 43kDNK & NKT

cells

with CD94, Qa-1(b) receptor,

inhibitorysignaling

CD159c NKG2CC-typelectin

NK & NKTcells

with CD94, Qa-1(b) receptor,

stimulatorysignaling

CD160 BY55 27kD IgSFNK subset, T

subset costimulation

CD161c

NKR-P1c,Ly-55, NK1.

1 40kDC-typelectin NK, T subset

NK cell-mediated

cytotoxicity

CD162PSGL-1,

Slp1 120kDMucinfamily

myeloid cells,lymphocyte

subset

CD62P &CD62L

receptor,adhesion,leukocyte

rollingCD162R

(H) PEN-5not defined in

mouse

CD163100-

130kD SRCRSFperitoneal

mac

CD164MGC-24,

A115, A24 80kD Sialomucin

mRNA: broadvarious adult& embryonic

tissues

hematopoieticprogenitor-

stromainteraction

CD165 AD2, gp37not defined in

mouse

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CD166 ALCAM 120kD IgSF

neurons,Tact, mono,

epith,fibroblasts

CD6 receptor,adhesion, T

development,T-B interaction,role in nervous

system

CD167a DDR1 120kDRTK

family

epith,myoblasts,brain, early

markerneuroectoderma

discoidindomain

receptor,tyrosine kinase,

adhesion

CD168RHAMM,

Hmmr70-

73kD broad

hyaluronan-mediatedmotility

receptor,adhesion, celllocomotion,

tumormetastasis

(intracellular inhuman breast

cancer)

CD169sialoadhesin,Sn, Siglec-1 185kD IgS

tissue macsubset

adhesion, cell-cell & cell-

matrixinteractions,

binds alpha2,3-sialylated

ligands CD43,CD227, SRBC-

RCD170

(H)Siglec-5,

CD33-like2 140kDIgSF,

sialoadhesinsmac subset,neutrophils adhesion

CD171

L1, celladhesionmolecule

200-210kD IgSF

CNS, PNS,glial cells,mono, T

subset, B,DC, lymph

node reticularfibroblasts,some epith

homotypicadhesion, T co-

stimulation,integrin binding,

KO hasneuropathologies

similar toCRASHdisorder

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CD172aSIRPalpha,

Ptpns1 110kD IgSF

mono, mac,DC, T

subset, stemcells

adhesion, withCD47, SHPsubstrate-1

CD172b SIRPbeta60-

90kD

Ig-likeType I

cellsurfacereceptor

mac andother

hematopoieticlineages

engagement ofSIRPbetapromotes

phagocytosis inmac

CD172g(H) SIRPgamma

not defined inmouse

CD173-CD175(H) CHO

CD176

Trf,transferring,

Tfn, HP CHO

CD177 NB156-

62kDGPI-

linked

neutrophilsubset

(surface &intracellular)

CD178

Fas Ligand,CD95L,TNFSF6

38-42kD TNFSF Tact, testis

apoptosis ofCD95+ cells,

immuneprivilege,

soluble form inserum, gldmutation

nonfunctionalFasL

CD179a V pre B 16kD IgSFpro- & early

pre-B

Bdifferentiation,signaling, pre-

BCR withIgM/CD79alpha/beta

CD179b Lambda 5 22kD IgSFpro- & early

pre-B

Bdifferentiation,signaling, pre-

BCR withIgM/CD79alpha/beta

CD180RP105, Ly-

7895-

105kDLRRF,TLRSF B, mono, DC

B recognition &signaling of

LPS, with MD-1

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CD181CXCR1,

IL8Ralpha 39kDGPCRfamily

neutrophils,basophils,

NK, T subset,mono

binding of IL-8induces

chemotaxis ofneutrophils

CD182CXCR2,IL8Rbeta 40kD

GPCRfamily

neutrophils,basophils,

NK, T subset,mono

binding of IL-8induces

chemotaxis ofneutrophils,

also binds GROand NAP-2

CD183

CXCR3,Cmkar3,

gpr9 40kD TM7SF

Tact (Th1),NK,

eosinophils,GM-CSFactivated

hematopoieticprogenitors

6Ckine, IP-10 ,Mig & I-TACreceptor, T

recruitment toinflammatory

sites,Th1response,allograft

destruction

CD184

CXCR4,Cmkar4,

Fusin/LESTR 45kD TM7SF

T subset, B,DC, mono,

endoth

SDF-1receptor,

embryogenesis,(human: X4

HIV-1coreceptor)

CD185CXCR5,

BLR1 45kDGPCRfamily

spleen,resting B, T,skin-derived

DC

binds BLC,involved in B-cell migration

into B-cellfollicles ofspleen and

Peyer’spatches

CD186CXCR6,BONZO 40kD

GPCRfamily memory T

chemokinereceptor for

CXCL16, also acoreceptor bySIVs and by

strains of HIV-2and m-tropic

HIV-1

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CD191

CCR1, MIP-1alphaR,

RANTES-R 39kDGPCRfamily

neutrophils,mono, lymph,eosinophils &osteoclasts

receptor for C-C type

chemokinesMIP-1alpha,

RANTES, MIP-1beta, MCP-1

CD192CCR2, MIP-

1alphaR 40kDGPCRfamily

T subset,mono, B

receptor for theMCP-1, MCP-3

& MCP-4chemokines

CD193CCR3, MIP-1alphaRL2 45kD

GPCRfamily

skeletalmuscle & lowamounts in

leukocytes, Tsubset

receptor for C-C type

chemokineseotaxin, MCP-3, MCP-4 and

RANTES

CD195CCR5,Cmkbr5 45kD TM7SF

T subset, NK,monolow

MIP-1alpha,MIP-1beta &

RANTESreceptor,

(human: R5HIV-1

coreceptor)

CD196CCR6,KY411 45kD

GPCRfamily

mainly B, Tand DCsubset

receptor for C-C type

chemokinesMIP-

3alpha/LARC

CD197CCR7,Cmkbr7 45kD TM7SF T, DC subset

6Ckine & MIP-2beta receptor

CD198CCR8,TER1 50kD

GPCRfamily

mono, mac,neutrophils, T

subsetreceptor forTCA-3/I-309

CD199CCR9,

CMKBR10 43kDGPCRfamily

high inthymus,

immatureand mature T

receptor forchemokine

SCYA25/TECK,role in T

development

CD200 OX-245-

50kD IgSF

thymocytes,B, Tact, DC,

endoth,neurons

T costimulation,regulation of

oxidoreductasepathway

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CD201Procr,EPCR 50kD

endoth &stem cellsubset

activatedprotein Creceptor

CD202b Tie2, Tek 140kDRTK

family

stem cells,endoth from

earlydevelopment

angiogenesis,Angiopoietin-1

receptor

CD203cENpp1, PC-

1, TWY 115kDType II

TM

antibodysecreting B,basophils,mast cells,

megakaryocytes,glioma

plasma cellalloantigen,

ectoenzyme,binding/clearanceof extracellular

nucleotides

CD204

Macrophagescavenger-

R, Scvr 220kD macendocytosis of

macromolecules

CD205DEC-205,

Ly75 205kD

macmannosereceptor

SF

DC, thymicepith, Blow,BM stromal,pulmonaryepith, braincapillaries

antigen up-take/presentation,

immuneinhibition

CD206

macrophagemannose-R,

Mrc1 180kDmac, mono,DC subset

phagocytosis /pinocytosismannosecontainingmolecules

CD207 Langerin 40kDType II

TMLangerhans

cells

Ag capture &endocytic

receptor, withBirbeckgranules

CD208(H)

DC-LAMP,Lamp3

70-90kD

DCact,interdigitating

DC

CD209DC-SIGN,

CIRE 44kD DC subset

ICAM-3receptor, HIV-1binding protein,

T-DCinteraction

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CD210 IL-10R90-

110kD

Th1, B, NK,mono, mastcells, mac

IL-10 receptor,signaling,

related to IFNreceptors

CD212 IL-12Rbeta1 100kD

dimer &oligomerType I

TM Tact, NKact

high affinitybinding to IL-12, with IL-12

receptor beta2,signaling, T &

NK response toIL-12

CD213a1

IL-13Ralpha1,

NR4 65kD CRSF

mono, NK,fibroblasts,

endoth

binds IL-13 lowaffinity, with

CD124

CD213a2IL-

13Ralpha2 65kD CRSF B, monobinds IL-13high affinity

CD217 IL-17R 120kD broad IL-17 receptor

CD218a

IL-18Ralpha,

IL1Rrp 70kDIL-1Rfamily T, NK & DCs

IL-18 bindingleads to theactivation ofNF-kappaB

CD218bIL-18Rbeta,

IL18Rap 70kDIL-1Rfamily

T, NK andDCs

formsheterodimericreceptor with

IL-18Ralpha toenhance IL-18

binding

CD220InsulinR,

Insr140 &70kD

RTKfamily broad

Insulinreceptor,

regulation ofmetabolism

CD221 IGF-1R140 &70kD

RTKfamily broad

binds IGF highaffinity,

prolif/differentiation

CD222IGF-II R,

M6P/IGF2R220-

250kDType I

TM

broad, 90-95%

intracellular

cation-independentmannose 6-phosphatereceptor,

TGFbeta-LAP,plasminogen &

proliferinreceptor

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CD223 LAG-3 70kD IgSF Tact, Nkact

MHC class IIligand, role innatural killing

CD224 GGT, Ggtp27,

68kD

yolk sac,protoplasmicastrocytes,

endoth,embryonicstem cell

lines

gamma-glutamyl

transpeptidase

CD225

Ifitm1,fragilis2,

Mil2primordialgerm cells

adhesion,differentiation,

interferon-induced

transmembraneprotein 1

CD226

DNAM-1,PTA-1,TLiSA1 IgSF

Th1, CD8 T,platelets

plateletactivation, T

differentiation,costimulation,Th1 function

CD227 Muc1, EMA 300kD

Mucinfamily

type I TM

lymphocytes,tumors, epith,increased inpregnancy

epithelialmembrane

antigen,organogensis

CD228Melanotransferrin,

Mfi280-

95kD TransferrinSF

mRNA:cartilage

(high), testis(moderate)

CD229Ly-9,

Lgp10095,

110kD IgSF

thymocytes,T, B, BM

subset, noterythrocytes adhesion

CD230

Prionprotein,

PrnP 35kD

neurons,lymphocytes,

othercells

Scrapie-associatedfibril protein

CD231TALLA-1,

A1530-

45kD TM4SF

mRNA: brain,colon,

muscle,heart, kidney,

spleen

T cell acutelymphoblastic

leukemiamarker,neuronalfunction

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CD232VESP-R,PlexinC1 200kD broad

viral-encodedsemaphorin

protein receptor

CD233Band3,

SLC4A1 90kD

Anionexchanger

F

erythrocytes,mRNA: epith,other tissues

anion pump,CO2 transport,

linkingmembrane tocytoskeleton

CD234Duffy, Dfy,

DARC36-

37kD

mRNA:spleen, BM,liver, brain,

noterythrocytes

Duffy bloodgroup antigen

chemokinereceptor

CD235aGlycophorin

A, Gypa 36kD erythrocytes

one gene onlyin mouse for

Glycophorin A

CD236RGlycophorin

C 32kD erythrocytes

CD238Kell bloodgroup, Kel 110kD

erythrocytes,mRNA:spleen

CD239(H) B-CAM, Lu

78-85kD IgSF

mRNA:broad,

erythrocytes

Lutheran bloodgroup, B

adhesion tolaminin

CD240CE(H)

Rhesus30CE

30-32kD erythrocytes

Rh30CE &RH30D is one

gene in themouse: RH30

CD241Rhesus 50,

RhAg 50kD TM12SF erythrocytes

Rh antigenswith CD47 &

LW

CD242(H)

ICAM-4, LWblood group 42kD IgSF erythrocytes

adhesion,Landsteiner-Wiener blood

group

CD243MDR-1,

Abcb1, Pgp 170kD

T subset,stem cells,

smallintestine,

kidney

ion pump,cytokine export,

CTL function

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CD2442B4, Ly-90,

Nmrk 78kDType II

TM, IgSFNK, NKT,

LAK

NK activation,CD48 receptor,

MHC-unrestricted

killing

CD246 ALK, Ki-1 200kDRTK

family

mRNA: brain,not normal

lymphocytes

anaplasticlymphoma

kinase, braindevelopment

CD247TCR zeta,

cd3z 16kDRTK

family T, NK subset

TCR subunit,signaling, lowlevel impaired

immunefunction

CD248TEM1,

Endosialin 175kDC-TypeLectin endoth tissue

may function intumor

progressionand

angiogenesisCD249

(H)Aminopeptidase

Anot defined in

mouse

CD252

OX-40Ligand,gp34 35kD TNFSF

Bact, cardiacmyocytes

T-B interaction,T costimulation

CD253TRAIL,APO-2L TNFSF

NKact, liverNK apoptosis

CD254

TRANCE,RANKL,OPGL ~35kD TNFSF

Tact,osteoblasts

T-DCcommunication,

osteoclastdifferentiation

CD256APRIL,TALL-2 16kD TNFSF

Tact, mono,mac

binds TACI andBCMA

CD257

BLyS,BAFF,TALL-1 45kD TNFSF mono

binds TACI,BCMA &

BAFFR toinduce B

proliferation

CD258LIGHT,

HVEM-L 28kD TNFSFTact,

immature DC

binds LTBR toinduce T

proliferation,also binds

HVEMCD261

(H) TRAIL-R1not defined in

mouse

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CD262

TRAIL-R2,DR5, Apo2,

TRICK2,KILLER TNFRSF broad

ligand forTRAIL,

activates NF-kappaB &mediates

apoptosis, p53-dependentexpression

CD263(H) TRAIL-R3

not defined inmouse

CD264(H) TRAIL-R4

not defined inmouse

CD265

RANK,TRANCE-R,

ODFR 97kD TNFRSFbroad

expression

binding ofTRANCEmediates

osteoclastogenesis& T-DC

interactions

CD266

TWEAKReceptor,

Fn14 14kD TNFRSF

mRNA inliver

regeneration,Colon 26 cell

line

cell migration,proliferation,

angiogenesis,activates NF-

kappaBpathway

CD267TACI,

TNFRSF13b 32kD TNFRSF Tact and B

binding ofAPRIL or BLyS

stimulates Band T function

CD268BAFFR,Bcmd 25kD TNFRSF B

BLyS bindingpromotessurvival of

mature B & Bresponse

CD269BCMA,

TNFRSF13B 20kD

Type IIITM,

TNFRSF

mature B(membrane

andperinuclear)

binds APRIL,BAFF, survival

andproliferation

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CD271

NGFR,TNFRSF16,p75 (NTR),

Bex3,Ngfrap1 45kD TNFRSF

neurons,mesenchymal

stem cells

binds NGF,BDNF, NT-3and NT-4,

tumorsupressor

mediate cellsurvival and

death

CD272

BTLA, B & TLymphocyteAssociated 33kD IgSF

T, B , BM,splenic macs,BM derived

DC

binds HVEM,negative

regulation

CD273

B7DC, PD-L2,

PDCD1L2 25kD IgSFDC subset,mono, mac

binds PD-1, co-stimulation or

supression of Tcell proliferation

CD274

B7-H1, PD-L1,

PDCD1LG1 33kD IgSF

leukocytes,decrease in

maturethymic T cells

binds PD-1,proliferationand cytokineproduction

CD275

B7-H2,GL50,

ICOS-L,B7h, B7RP-

1 60kD B7 familyAPC, B, DC,

mac

lymphocytecostimulation,receptor for

ICOS

CD276B7-H3,B7RP-2

40-45kD B7 family

in vitrocultured DCand mono

negativeregulator of Tcell activation

CD277(H) BT3.1

not defined inmouse

CD278

ICOS,Inducible T

cellCOStimulator

, Ly11555-

60kDCD28family Tact, Th2

T costimulation,B7-H2 receptor,

cytokineproduction

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CD279

PD-1,programmed

death-1 55kD IgSF Tact, Bact

negativelyregulates

lymphocytes, Tcell

development

CD280

ENDO180,UPARAP,

MRC2 180kDCD28family chondrocytes

binds uPAR,mannosereceptor,

collagen matrixremodeling &

endocyticrecycling

CD281 TLR1 90kDTLR

familylow levels inleukocytes

innateimmunity, with

TLR2

CD282 TLR2 90kDTLR

family

myeloidlineage: mac

& DC inspleen

response tobacterial

lipoproteins

CD283 TLR3 100kDTLR

family

DC subset,mac,

fibroblasts,induced by

LPS

binds dsRNA,activation ofNK-kappaB

CD284TLR4, Ly87,

Rasl2-8 100kD

TLRfamily,ASV

thioglycolate-elicited

peritonealmac

binds LPS,innate immunity

CD289 TLR9 120kDTLR

familyDC subset

(intracellular)binds CpG-

DNA

CD292BMPR1A,

ALK3 57kD

Type I,BMP

receptor

boneprogenitor,

broad

binds BMP 2 &4, bone

development,germ layer

specification

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CD293BMPR1B,

ALK6 57kD

Type I,BMP

receptor

boneprogenitor,developing

retina

binds BMP,bone

development,neurogenesis

CD294CRTH2,GPR44

55-70kD

GPCR-7TM

Th2,eosinophils,basophils

bindsprostaglandin

D2, chemotaxis

CD295LeptinR,

LEPR 132kD

Type Icytokine-

likereceptor,

ASV broad

adiposemetabolism,

may beinvolved in

immunedysfunction in

obesity

CD296ART1, RT6,

ART2 37kDADP-

ribosyltransferase

heart andskeletalmuscle,

peripheral T,NK subset

GPI linkedprotein modifiesintegrin duringdifferentiation

CD297

ART4,dombrock

blood group 38kDADP-

ribosyltransferase

heart, lung,liver, andspleen,

erythroid,monoact

CD298

Na+/K+-ATPasebeta3

subunit,ATP1B3 52kD broad transporter

CD299(H)

DC-SIGN-related

not defined inmouse

CD301-302(H)

not defined inmouse

CD303Clecsf10,dectin-2

C-typelectin

domainfamily 4

tissue mac,DC,

upregulatedon blood

mono

inflammatorylesion, UV-

inducedtolerance

CD304 BDCA4,neuropilin

1,

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Nrp,NP-1 130kD

semaphorinfamily

DC,neurons,endoth &

tumorcells,

CD4+/CD25+Treg

bindsVEGF165,

semaphorins,coreceptorwith plexin,

axonalguidance,

angiogenesis,cell survival,

migration polyclonal

CD305 LAIR132-

40kDIgSF,ASV

broad, NK, B,T, mono

inhibitoryreceptor on NK

and T cellsCD306-307

(H)not defined in

mouse

CD309VEGFR2,

Flk-1, KDR 230kD

Type IIITM tyrkinase

endoth,angiogenicprecursor

cells;hemangioblast

binds VEGF,regulates

adhesion andcell signaling

CD312(H) EMR2

not defined inmouse

CD314NKG2D,KLRK1 42kD

Type IIlectin-likereceptor

NK, CD8+activated, notCD4+ in theperiphery,

macact

binds MHCclass I, Rae1 &

ULBP4,cytolysis and

cytokineproduction;

costimulatory

CD315

CD9P1,SMAP6,FPRP,

PTGFRN 135kD IgSFB subset,monoact

with CD81 andCD9

CD316

EWI2,PGRL,KASP

63-75kD

TM4SF,IgSF8

B, T, low onNK cells

with CD81 &CD9; involved

in cell migration

CD317 BST230-

36kD Type II

BM stromals,fibroblasts,

plasmacytoidDC

pre-B cellgrowth,

overexpressedin multiplemyeloma

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CD318

CDCP1,CUB

domaincontainingprotein 1

CD319CRACC,SLAMF7 66kD Ig TM

predicted: T,B and DC

subset, NK,upregulated

in DCregulate T and

NK cells

CD3208D6,VLDL

CD321

JAM1, F11receptor,

KAR 12.5kD

IgSF,Type I,AVS

epith andendoth,platelets

tight junction,binds reovirus

& LFA1,plateletreceptor

CD322JAM2, VE-

JAM 45kD IgSF

HEV andother

endothelia

mediatestransendothelial

migration oflymphocytes

CD324E-Cadherin,Uvomorulin 120kD

cadherinSF

non-neuralepith

binding tointegrin

alphaE/beta7 &homotypic

interactionsmediate cell

adhesion

CD325N-Cadherin,Cadherin-2 140kD

cadherinSF

brain,skeletal &

cardiacmuscle

adhesion, maybe involved in

neuronalrecognitionmechanism

CD326Ep-CAM,

EGP, Ly-74 40kDthymocytes,epith, DC

may functionas growth

factorreceptor oradhesionmolecule

CD327(H) siglec6

not defined inmouse

CD328(H) siglec7

not defined inmouse

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CD329siglec9,siglecl1 IgSF

monocyte/myeloidcells

mediates sialic-acid dependentbinding to cells

CD331

FGFR1,FLT2, N-

SAM 30kDTM tyrkinase

fibroblasts,epithelial

binds FGF,wound healing,

bonedevelopment

CD332

FGFR2,KGFR,KSAM

115-135kD

TM tyrkinase

fibroblasts,epithelial,

ectoderm ofembryo

binds FGF,embryonic limbdevelopment,

AER

CD333FGFR3,

ACH, CEK2 115kD

TM tyrkinase,

ASV

fibroblasts,epithelial,astrocytes

binds FGF,bone & CNSdevelopment

CD334FGFR4,

TKF 110kDTM tyrkinase

fibroblasts,epithelial,

hepatocytes

binds FGF,bone

development

CD335NKp46, Ly-94 homolog 46kD IgSF NK

binds non-MHC, NKactivation

CD336(H) NKp44

not defined inmouse

CD337(H)

Ncr3, IC7,Ly117

mouse IC7mRNA in

liver

CD338

ABCG2,Mxr,

ABC15,BCRP1 73kD

GPCR7TM

stem cellsubset (sidepopulation)

Multi-drugresistancetransporter

CD339Jagged-1,Serrate1 135kD EGF TM

BM stromal &mac, stromal

cell lines

receptor forNotch-1, 2, & 3,hematopoiesis,

Th2 fate