2nd NATIONAL BIOSAFETY CONFERENCE

5- 9th AUGUST, 2013

KENYATTA INTERNATIONAL CONVENTIONCENTRE (KICC), NAIROBI, KENYA

Organized by

NATIONAL BIOSAFETY AUTHORITY

Pre-Conference Courses Program August 5 - 6, 2013

Theme: Biosafety Advocacy for realization of Vision 2030

Date Time Room Pre-Conference Course Course Presenter/s

Mon

day

5thA

ugus

t 20

1308:00 -08:30

Registration NBA Secretariat

08:30 -13:00

Aberdares Biotechnology and BiosafetyRegulatory Framework in Kenya

Prof. Edward NguuProf. D. Ogoyi

14:00 - 17:30 Aberdares Emergency Responses Systems,Personal Protective Equipment andOccupational Health & Safety

Dr. Kiiyukia CiiraMr. Charles M. Mburu

08:30 -13:00 Lenana Biosafety Levels.Detection and Surveillance ofGMOs

Mr. Abed KagunduMr. George Ngundo

14:00 - 17:30 Lenana Decontamination and Wastehandling

Ms. Damaris MatokeMs. Milka Mwangi

08:30- 13:00 Taifa Food and Feed Safety Assessmentand Standards

Margaret AlekeProf. Theophilus Mutui

14:00 - 17:30 Taifa Transport of Biological Materials Juma BonventureNicholas Mwikwabe

Tues

day

6thA

ugus

t 201

2

08:00 -08:30

Registration NBA Secretariat

08:30 -13:00

Aberdares Environmental Risk Assessment ofGM Crops:Case studies on non-targetOrganisms

Dr. M. WachMr. Josphat MuchiriMs. Julia NjagiMr. Thomas Bwana

14:00 - 17:30 Aberdares Developing Institutional ResearchCompliance Committees

Ms. Ephy KhaembaMs. Sylvia Wanjiru

08:30 -13:00 Lenana Transport of Biological Materials(continuation)

Dr. Juma BonventureDr. Nicholas Mwikwabe

14:00 - 17:30 Lenana Bioethics, Biosecurity and Dual UseResearch of concern

Ms. Cecilia RumberiaMr. Albert Bunyasi

08:30- 13:00 Taifa Design, Construction &Maintenance of High Bio-containment Facilities.Design & Maintenance of IsolationFacilities

Dr. David MburuEng. Josphat Wamburu

14:00- 17:30 Taifa Biosafety Cabinets, Fume Hoods &Clean Benches

Mr. Gabriel OkondoMs. Beth Njaramba

Feedback forms should be filled after every course

PRE- CONFERENCE COURSES OBJECTIVES

1. BIOTECHNOLOGY AND BIOSAFETY REGULATORY FRAMEWORK IN KENYA

Prof. Nguu and Prof. Ogoyi

Objectives To equip participants with basic facts on biotechnology development and its

potential applications. To highlight key biosafety concerns on GM development and applications To enlighten participants on current status regulatory framework in Kenya

Contents

The development of modern biotechnology Key concerns on use of modern biotechnology Biosafety Law: Alignments to International Conventions Operationalization of Biosafety Regulatory Framework in Kenya: Where are we?

2. INTRODUCTION TO EMERGENCY RESPONSE SYSTEM, PPE AND OCCUPATIONALHEALTH AND SAFETY

Dr. Kiiyukia and Mr. Charles M. Mburu

Objective:

To summarize the general elements of a health and safety program includingemergency preparedness and use of PPE in workplaces.

Emergency preparedness to deal with biohazards, fire and other relatedaccidents.

To develop programs to deal with their workplace safety specific needs.

a) Occupational health and safety:

Identify and characterize workplace hazards Assess risks associated with biohazards Evaluate precautions and preparedness of GMO Identify correct processes and procedures of controlling those hazards associated

with GMFs. Investigation and inspection techniques of accidents and near misses Reduce incidents, accident and injury reporting procedures Planning and budget process elements that affect the OSH program. Program overview to control and manage hazardous materials.

b) Emergency preparedness To identify and describe ethical standards for the profession of emergency

management of biohazards. To define and critique definitions of bio-disaster To discuss about the biohazards emergency preparedness To discuss the fire hazards emergency preparedness To discuss and debate hazard-specific and all-hazard emergency approaches to

disaster. To describe and critique the comprehensive emergency management approach. To assess the future of emergency management policy and programs of

biohazards

c) The personal protective equipment

Explain the importance of wearing Personal Protective Equipment (PPE) Types of PPE Identify PPE Responsibilities: management to select PPE appropriately to task and

to require its use, Employees to use selected PPE consistently and correctly Identify some of the uses and limitations of protection provided by specific types

of PPE Focusing on common examples of eye/face, head, body, foot, and hand

protection Explain the importance of assuring good fit and how to inspect, clean, and

maintain PPE Appropriate PPE for handling the bio-hazardous materials

3. BIOSAFETY LEVELS

Mr. AbedKagundu

Objectives: To carry out a comprehensive analysis of a proposed GM activity to ascertain its

safety to human health and the environment.

Content: Determine the nature of the DNA sequences to be transferred, donor organism of

the insert, pathogenicity of the GMO and potential hazards. Risk assessment determines the containment level/Biosafety level Classification of the contained-use levels

4. DETECTION METHODS FOR GENETICALLY MODIFIED ORGANISMS

Mr. George Ngundo

Objectives:

The aim of GMO testing is to mitigate the risk of unapproved GM seeds beingreleased in the Kenyan environment.

Content: Sampling methods and sample preparation: Grinding and DNA Extraction Lateral strip test Qualitative and Quantitative PCR tests Interpreting and Reporting Test Results

5. DECONTAMINATION AND WASTE HANDLING

Ms. Damaris Matoke Muhia and Ms. Milka Mwangi

Objectives: To train participants on key waste management processes To explain on the importance of environmental management To enlighten participants on waste regulations in Kenya

Content: Waste definitions and characteristics Train on various waste categories and management processes Guidelines for hazardous waste disinfection, decontamination and disposal Create awareness on biological waste management regulations in Kenya Risks associated with irresponsible waste handling Environmental Management Coordination Act; EMCA 1999

6. STANDARDS FOR FOOD AND FEED SAFETY

Ms. Margaret Aleke

Objective: Create awareness on food/feed safety standards

Content: Create awareness of standards for food and feed derived from recombinant-DNA Create awareness on methods for analysis of foods derived from recombinant DNA

7. FOOD AND FEED SAFETY ASSESSMENT (RISK ANALYSIS)

Dr. Allan Liavoga

Objective: Create understanding of food and feed safety assessment

Content: Explain risk analysis in food and feed Define food and feed safety; and food safety assessment Explain the different approaches for food and feed safety assessment in

conventional foods and feed derived from recombinant DNA materials.

8. TRANSPORT OF DANGEROUS GOODS TRAINING

Dr. Juma Bonventure and Dr. Nicholas Mwikwabe

ObjectivesThe objective of the training is to equip the trainees with the requirements of shipping ofdangerous goods as spelled out by the UN, IATA and ICAO as a requirement. The trainingwill be hands own and will be divided into 6 modules. It will be organized into lectures,exercises and assessments. There will be a pre and post-assessment and the successfulcandidates will be awarded a two years certificate for packaging documenting and shippingdangerous goods as per the internal regulations referred above.

Content• Module I: Terms Used for Shipping• Module II: Classification of Infectious Substances• Module III: Packaging of Infectious Substances• Module IV: Labeling and Marking Packages• Module V: Shipping Documentation• Module VI: Shipping with dry ice• Module VII: FAQ and tools• Final Assessment• Certificate of Successful Completion

TUESDAY, 6TH AUGUST 2013

9. ENVIRONMENTAL RISK ASSESSMENT OF GM CROPS: CASE STUDIES ON NON-TARGETORGANISMS

Dr. Michael Wach, Mr. Josphat Muchiri, Ms. Julia Njagi and Mr. Thomas Bwana

Objectives To provide participants with an understanding of the principles of environmental

risk assessment of GM crops.

To highlight the use of laboratory and field tests in the assessment of risks to non-target organisms (NTOs).

To use case studies to provide hands-on experience in the risk assessment of insect-resistant crops.

Contents Key Considerations in the Environmental Risk Assessment of GM Crops Assessment of Impacts to Herbivorous Insects Assessment of Impacts to Beneficial Insects Use of Field Observations in NTO Risk Assessment Small group exercise--Insect-resistant Crop Case Studies

10. DEVELOPING INSTITUTIONAL RESEARCH COMPLIANCE COMMITTEES

Ms. Ephy Khaemba and Ms.Sylvia Wanjiru

ObjectivesTo make participants aware of the legal requirements to establish IBCs beforeembarking on any genetic modification work.

Content Composition Functions SOPs / Biosafety Manual

11. BIOETHICS, BIOSECURITY AND DUAL-USE RESEARCH OF CONCERN

Ms. Cecilia Rumberia and Mr. Albert Bunyasi

BioethicsObjectives

The purpose of this course is to provide students with an introduction to thehistorical and theoretical foundations of bioethics. To present the basic concepts,principles, and elements of bioethics

Content The history and development of key international institutions and regulatory

documents, pivotal policies, theoretical frameworks informing internationalbioethics and research ethics, and case studies of specific areas in internationalbioethics.

Describe the ethical responsibilities for individuals working with infectious diseaseagents in the laboratory.

Outline the ethical issues that concern biosafety and biosecurity Discuss codes of conduct for scientists Identify key international codes and conventions in relation to the safe and ethical

use of biological sciences

BiosecurityObjectives Develop awareness and understanding of the concepts of biosafety and biosecurity,

and its relevance to biosecurity within the laboratory. Develop knowledge of approaches to the conduct of biosafety and biosecurity risk

assessments, and be able to provide strategies to appropriately manage these risks.Dual use in researchObjectives Create awareness on the historical and regulatory perspective of Dual Use Research

of Concern Develop awareness and understanding of a range of dual-use conundrums and

dilemmas that arise due to the impact of science and technology on society; Develop awareness and understanding of the ethical, legal and social relevance of

dual-use biosecurity Create an understanding of the regulations governing life science research. Familiarize on the Dual Use Research (DURC) criteria. Steps by the Institution to address the issue of DURC.

12. DESIGN, CONSTRUCTION AND MANAGEMENT OF HIGH BIO-CONTAINMENTFACILITIES

Dr. David Mburu

Objectives To identify factors that governs the design of a high bio-containment facility. To summarize the roles of key professionals involved in setting up a BSL3 laboratory. To outline the significance of the Heating, Ventilation and Air Conditioning (HVAC)

system in biosafety. To reinforce the central role of the Building Management System (BMS) as the nerve

centre for a BSL3 facility. To present an operational strategy cognizant with the industry optimal.

Content Design consideration Project management Builder’s requirements Laboratory services matrix HVAC system BMS consideration Facility management

13. DESIGN AND MAINTENANCE OF ISOLATION FACILITIES

Eng. Josphat Wamburu

Objectives To identify factors that governs the design and maintenance of isolation.

Content Engineering Interventions in IPC (Infection prevention& Control) Design & Maintenance of Contact Isolation Facilities. Design & Maintenance of air-borne Infection Isolation Facilities

14. BIOSAFETY CABINETS, FUME HOODS & CLEAN BENCHES

Mr. Gabriel Okondo and Ms. Beth Njaramba

Objectives• To discuss different types of Biological Safety Cabinets (BSCs) and their applications

Content• Selection limitations of BSCs and their application• Proper Use of BSCs• HEPA Filters : How they work• Decontamination and Annual Certification per NSF Std 49, EN Std, etc.