22 Biology 2-6-08 Nervous System 2 CNS

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    Your Nervous SystemYour Nervous System

    Central Nervous SystemCentral Nervous System

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    Engag eEngag e

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    ExploreExplore

    C lay Br ain sC lay Br ain s

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    ExplainExplain

    CNSCNSRe lays mess ag esRe lays mess ag esProcesses inf orm a tionProcesses inf orm a tion

    Analyzes inf orm a tion Analyzes inf orm a tion

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    P a rts o f CNSP a rts o f CNS

    1.1. TheThe Spinal CordSpinal Cord2.2. TheThe BrainBrain

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    Protect ionsProtect ionsSku ll and Vertebr aeSku ll and Vertebr ae33 protect ive layers c alle d protect ive layers c alle d meningesmeninges

    1.1. Dura Mater Dura Mater (outer layer): co ns ists o f co nnect ive t issues,(outer layer): co ns ists o f co nnect ive t issues,bloo d vesse ls, and nerves.bloo d vesse ls, and nerves.

    2.2. Arachnoid Layer Arachnoid Layer (m iddle layer): e last ic and web like(m iddle layer): e last ic and web like3 .3 . Pia Mater Pia Mater (inner layer): co ntains nerves and b loo d (inner layer): co ntains nerves and b loo d

    vesse ls.vesse ls.4.4. Cerebrospinal fluidCerebrospinal fluid

    a cle a r wa tery liqu ida cle a r wa tery liqu idse pa r a tes the m iddle and inner layersse pa r a tes the m iddle and inner layersActs a s shock absorber Acts a s shock absorber e xch ang e o f nutr ie nts betwee n b loo d and nervous systeme xch ang e o f nutr ie nts betwee n b loo d and nervous system

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    Po ns

    P ituita ry gland

    Hypoth ala mus

    Cerebrum

    Medulla ob longa ta S pinal cor d

    Cerebe llum

    P ineal gland

    Thala mus

    Section 35-3

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    The Br ainThe Br ain

    The br ain is theThe br ain is thecontrolcontrol center center of theof thebodybodyIt is aboutIt is about 2%2% of your of your bo dybo dy weightweight and and usesuses 20%20% of your of your bo dysbo dys oxygenoxygen

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    P a rts o f the Br ainP a rts o f the Br ain

    Divide d intoDivide d into threethree pa rtspa rtsCerebrumCerebrum

    Cerebe llumCerebe llumBr ain StemBr ain Stem

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    CerebrumCerebrum

    1.1. LargestLargest pa rt o f the br ain pa rt o f the br ain Le a r ning and Se nsesLea r ning and Se nses

    2 hemispheres2 hemispheres -- R ight and Le f tR ight and Le f tCo nnecte d by theCo nnecte d by the Corpus CallosumCorpus CallosumRight sideRight side co ntro lsco ntro ls-- left sideleft sideLeft sideLeft side co ntro lsco ntro ls r ight s ide o f bo dyr ight s ide o f bo dy

    Four sect ionsFour sect ions -- LOBESLOBES1.1. FrontalFrontal Lobe 2.Lobe 2. ParietalParietal LobeLobe3.3. OccipitalOccipital Lobe 4.Lobe 4. TemporalTemporal LobeLobe

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    G r ay Ma tter vs. Wh ite M a tter G r ay Ma tter vs. Wh ite M a tter

    G ray Matter G ray Matter Abse nce o f mye lin in Abse nce o f mye lin in ma sses o f neuro ns accou nts f or the gr ayma sses o f neuro ns accou nts f or the gr ay

    ma tter o f the br ain ma tter o f the br ain Cerebral CortexCerebral CortexW hite Matter W hite Matter -- Mye linate d neuro ns givesMye linate d neuro ns givesneuro ns a wh ite app e a r an ceneuro ns a wh ite app e a r an ce inner layer inner layer

    of cerebrumof cerebrum

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    Cerebe llumCerebe llum

    Seco nd lar gestSeco nd lar gestloc a te d loc a te d belowbelow thethecerebrum a t b ack o f cerebrum a t b ack o f

    sku ll sku ll Th is pa rt isTh is pa rt isres pons ible f or theres pons ible f or thebalancebalance and and musclemusclecoor dina tioncoor dina tion

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    Br ain StemBr ain Stem

    Co nnects theCo nnects the brain tobrain to spinal cordspinal cordTheThe Two RegionsTwo Regions act a s sw itchbo a r dact a s sw itchbo a r d

    Medulla OblongataMedulla Oblongata Co ntro ls he a rt r a te,Co ntro ls he a rt r a te,bre a th ing r a te, and flow o f b loo d throu ghbre a th ing r a te, and flow o f b loo d throu ghthe b loo d vesse ls.the b loo d vesse ls.PonsPons Re lays s ignal s betwee n theRe lays s ignal s betwee n the

    cerebrum and the cerebe llumcerebrum and the cerebe llum

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    Po ns

    P ituita ry gland

    Hypoth ala mus

    Cerebrum

    Medulla ob longa ta S pinal cor d

    Cerebe llum

    P ineal gland

    Thala mus

    Section 35-3

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    S pinal Cor dS pinal Cor d

    Link betwee n br ain and rest o f bo dy (PNS)Link betwee n br ain and rest o f bo dy (PNS)31 pai rs o f s pinal nerves31 pai rs o f s pinal nerves

    Re fle xes processe d direct ly by s pinal cor dRe fle xes processe d direct ly by s pinal cor dReflexReflex qu ick, autom a tic, u nco nsc iousqu ick, autom a tic, u nco nsc iousres ponsesres ponses

    Resu lt o f Resu lt o f reflex arcsreflex arcs shortest nerve pa thw aysshortest nerve pa thw ays

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    Ela bor a tionEla bor a tion

    Nicotine in the Body and BrainNicotine in the Body and Brain

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    Drugs and the NervousDrugs and the Nervous

    SystemSystemDrug Drug an y subst an ce, other th an f oo d tha tan y subst an ce, other th an f oo d tha tch ang es the structure or f unct ion of thech ang es the structure or f unct ion of thebo dybo dyLe galLe galIlle galIlle gal

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    Drugs Th a t Aff ect the Sy nap seDrugs Th a t Aff ect the Sy nap se

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    U se d to incre ase alert ness,re lieve fatigue

    U se d to re lieve anxiety,irr itability, te ns ion

    U se d to re lieve pain

    St imu lants

    Depress an ts

    O pia tes

    Amphet am ines

    Ba rb itur a tesTr anq uilizers

    Mor phine

    Co de ine

    Incre ase he a rt and res pir a tory r a tes;e lev a te b loo d pressure; dilate pupils;decre ase app et ite

    S low down the act ions o f the ce ntr al nervous system; sm all amou nts c ausecalmness and re laxa tion; lar ger amou nts c ause s lurre d s peech and impaire d judgeme nt

    Act as a depress an t; c ause

    drows iness, rest less ness, na use a

    Section 35-5

    Commonly Abused Drugs

    Drug Type Medical Use Examples Effects on the body

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    1. St imu lan ts1. St imu lan tsIncre a seIncre a se

    He a rt r a teHe a rt r a teBloo d pressureBloo d pressureBre a th ingBre a th ingRe le ase o f neurotr an sm itters a t some sy nap ses in theRe le ase o f neurotr an sm itters a t some sy nap ses in thebr ain br ain

    De plete neurotr an sm itters and le ad to:De plete neurotr an sm itters and le ad to:Fa tigueFa tigue

    C ircu latory prob lemsC ircu latory prob lemsHalluc ina tionsHalluc ina tionsDe press ionDe press ion

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    2. De press an ts2. De press an tsDecre a seDecre a se

    He a rt r a teHe a rt r a teBre a th ing r a teBre a th ing r a te

    Bloo d pressureBloo d pressureRe lax musc lesRe lax musc lesRe lieve te ns ionRe lieve te ns ion

    Enhan ces re le a se o f neurotr an sm ittersEnhan ces re le a se o f neurotr an sm itters

    tha t preve nt nerves ce lls f rom fir ingtha t preve nt nerves ce lls f rom fir ingAlcoho l with de press an ts c an le ad to Alcoho l with de press an ts c an le ad tode a thde a th de presses CNS to a po int o nede presses CNS to a po int o nesto ps bre a th ingsto ps bre a th ing

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    3. O pia tes3. O pia tes

    Mim ics e ndor ph insMim ics e ndor ph insEndorphinEndorphin na tur al chem ical in br ain tha t he lpsna tur al chem ical in br ain tha t he lpsovercome pain overcome pain Whe n perso n sto ps t akingWhe n perso n sto ps t aking

    Br ain has ad juste d to h igh leve ls o f e ndor ph insBr ain has ad juste d to h igh leve ls o f e ndor ph insCann ot produce e nou gh na tur al e ndor phinsCann ot produce e nou gh na tur al e ndor phins

    Su ff er u nco ntro llab le pain and s icknessSu ff er u nco ntro llab le pain and s ickness

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    4. Coc aine4. Coc aine

    Su dde n re le ase o f Su dde n re le ase o f DopamineDopaminePower f u l St imu lan tPower f u l St imu lan tIncre a ses he a rt r a te and b loo d pressureIncre a ses he a rt r a te and b loo d pressureF irst t ime users c an have he a rt a ttackF irst t ime users c an have he a rt a ttackDopamineDopamine neurotr an sm itter in br ain tha t isneurotr an sm itter in br ain tha t isre le a se d to give f ee ling of ple a sure and re le a se d to give f ee ling of ple a sure and

    s a tis fact ions a tis fact ion

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    5 . Ma r i juana5 . Ma r i juanaAct ive ingre die nt (THC) tetr ahydroc anna b ino l Act ive ingre die nt (THC) tetr ahydroc anna b ino lMore destruct ive to lung s th an ciga rettesMore destruct ive to lung s th an ciga rettes

    5 ma r i juana cigs = 120 co nve ntional c igs5 ma r i juana cigs = 120 co nve ntional c igs

    Resu lts in:Resu lts in:Lower WBC cou nt by 40%Lower WBC cou nt by 40% - - susce ptib le to inf ect ionssusce ptib le to inf ect ionsTee nsTee ns

    inh ib its m a tur ityinh ib its m a tur ityRet a r ds norm al br ain growthRet a r ds norm al br ain growth

    Memory lossMemory lossIna b ility to co nce ntr a teIna b ility to co nce ntr a teFall short o n memory a s we ll a s m a th and verb al sk illsFall short o n memory a s we ll a s m a th and verb al sk ills

    MalesMales re duce d testostero ne leve ls and incre a ses estro ge n leve lsre duce d testostero ne leve ls and incre a ses estro ge n leve lsFem alesFem ales

    disturbs me nstru al cyc ledisturbs me nstru al cyc leDN A da mag e to e gg sDN A da mag e to e gg s

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    More Eff ects (FY I)More Eff ects (FY I)Impai re d perce ption Impai re d perce ption Loss o f coor dina tion Loss o f coor dina tion Incre a se d r isk o f acc ide ntsIncre a se d r isk o f acc ide ntsImpai re d judgeme ntImpai re d judgeme ntLoss o f mot iva tion Loss o f mot iva tion Dim inishe d inh ib itionsDim inishe d inh ib itionsIncre a se d he a rt r a teIncre a se d he a rt r a teAnxiety, pani c a ttacks, and pa r an o ia Anxiety, pani c a ttacks, and pa r an o ia Halluc ina tionsHalluc ina tionsDamag e to the res pir a tory, re product ive, and immu ne systemsDamag e to the res pir a tory, re product ive, and immu ne systemsIncre a se d r isk o f C ANC ERIncre a se d r isk o f C ANC ERPsycho logical de pe nde ncyPsycho logical de pe nde ncy

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    6 . Alcoho l6 . Alcoho lDe press an tDe press an tS lows down CNSS lows down CNS

    40% o f 5 0,000 h ighway de a ths a re c ause d by40% o f 5 0,000 h ighway de a ths a re c ause d bydr inking and dr ivingdr inking and dr iving1/3 o f homoc ides a ttr ibute d to e ff ects o f alcoho l1/3 o f homoc ides a ttr ibute d to e ff ects o f alcoho l$15 0 b illion dollars o f U .S. eco nomy alcoho l abuse$15 0 b illion dollars o f U .S. eco nomy alcoho l abusetre a tme nttre a tme nt

    Fet al Alcoho l Sy nd rome (F AS)Fet al Alcoho l Sy nd rome (F AS)

    Dr inking wh ile pre gnan tDr inking wh ile pre gnan tHe a rt de f ects, m alf orme d faces, de laye d growth, poor He a rt de f ects, m alf orme d faces, de laye d growth, poor motor deve lopme ntmotor deve lopme nt

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    Alcoho l and Dise a se Alcoho l and Dise a se

    LongLong --term alcoho l use or bouts o f term alcoho l use or bouts o f e xcess ive co nsum ptione xcess ive co nsum ption

    Destroys liver ce llsDestroys liver ce llsC irrhos is o f liver C irrhos is o f liver f orm a tion of sc a r tissuef orm a tion of sc a r tissuetha t preve nts b loo d flow throu gh liver tha t preve nts b loo d flow throu gh liver

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    Drug AbuseDrug Abuse

    Inte ntional m isuse o f an y drug f or Inte ntional m isuse o f an y drug f or nonme dical pur posesnonme dical pur poses

    AddictionAddiction u nco ntro llab le de pe nde nceunco ntro llab le de pe nde nceon a drugon a drug

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    O nly Way to Preve nt Addict ion O nly Way to Preve nt Addict ion

    and Eff ects o f Drugsand Eff ects o f Drugs

    NO T taking them to be gin withNO T taking them to be gin with