2020 Urology Care Foundation Rising Stars in Urology Research Award 1 | P a g e

2020 Rising Stars in Urology

Research Award

Astellas, Inc.

Frank and Marion Hinman Urology Research Fund

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TABLE OF CONTENTS

I. Funding Opportunity Description ................................................................................................................ 3

A. Urology Care Foundation Mentored Research Awards ................................................................................. 3 B. Award Information ......................................................................................................................................... 3 C. Eligibility Information ..................................................................................................................................... 3 D. Funding Information ...................................................................................................................................... 4

1. Awards Available .................................................................................................................................. 4 2. Distribution of Funds ............................................................................................................................. 4

II. Preparation and Submission of Proposal Materials .................................................................................. 5

A. General Information ...................................................................................................................................... 5 B. Letter of Intent ............................................................................................................................................... 5 C. Preparation and Submission of the Proposal Package ................................................................................. 9

III. Proposal Review Information ..................................................................................................................... 11

A. Proposal Review and Selection Process ..................................................................................................... 11 B. Review Criteria ............................................................................................................................................ 11 C. Notification of Proposal Review Results ...................................................................................................... 12 D. Notice of Award ........................................................................................................................................... 13

IV. Award Requirements .................................................................................................................................. 13

A. Regulatory Approvals and Exemptions ....................................................................................................... 13 B. Reporting .................................................................................................................................................... 13

1. Progress Reports and Personal Statements ...................................................................................... 14 2. Post-award Reporting ......................................................................................................................... 14

C. Career Development Award Requirements ................................................................................................. 14 D. Urology Care Foundation Research-Related Activities ............................................................................... 15

1. AUA Annual Meeting Events .............................................................................................................. 15 2. Events at AUA Headquarters .............................................................................................................. 16

E. Publication Acknowledgements .................................................................................................................. 16 F. Changes to Project, Personnel, Institution, or Funding ............................................................................... 16

V. Urology Care Foundation Scholar Travel Support Program ................................................................... 17

VI. Contact Information .................................................................................................................................... 17

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I . FUNDING OPPORTUNITY DESCRIPTION

A. UROLOGY CARE FOUNDATION MENTORED RESEARCH AWARDS

The Urology Care Foundation, the official foundation of the American Urological Association (AUA), works to ensure the future of urologic health by supporting and improving the prevention, detection, and treatment of urologic diseases through research and patient education. The Urology Care Foundation has recognized a major need to encourage bright, young physician-scientists and researchers to dedicate their careers to improving patients’ lives through better understanding of the development and management of urologic diseases and conditions.

The AUA Office of Research, created in 2001, works toward its mission to advance urologic research through funding, education, and advocacy. The AUA Office of Research administers all aspects of Urology Care Foundation mentored research awards, including application receipt and review, as well as grant management. For any questions related to administration of awards or applications, see Section VI. Contact Information of this Program Announcement.

B. AWARD INFORMATION

The Urology Care Foundation recognizes the need to enable physician-scientists with the training, tools, and resources to succeed as independent researchers in urology. Protected time to conduct research, which is typically difficult to establish when balancing urology practice needs, is a major need identified in the physician-scientist community. The Urology Care Foundation developed the Rising Stars in Urology Research Award program to encourage physician-scientists who have shown significant promise by successfully competing for career development awards from federal and other funding sources, and to promote their pursuit of additional urologic research education and training. This program provides supplemental salary support to physician-scientist career development award recipients to ensure that their protected time for research remains stable and that their salary compensation is more competitive with their non-research urology faculty peers. Salary supplements will be awarded for a period of up to five years, commensurate with the time remaining on the existing career development award, with an escalating payment each year.

Rising Stars in Urology Research Awards are made possible through endowed funds generously established by Astellas, Inc. and the Frank and Marion Hinman Urology Research Fund.

C. ELIGIBILITY INFORMATION

To be eligible to compete for a 2020 Urology Care Foundation Rising Stars in Urology Research Award, the applicant must, by July 1, 2020:

- Be a board-certified or -eligible urologist, or participating in a training program to obtain board certification in urology;

- Have successfully competed for a new externally-funded, peer-reviewed, career development award1 (i.e., K07/K08/K23 awards from the National Institutes of Health (NIH), or career development-type grants from the Veterans Administration (VA), Department of Defense (DoD), American Cancer Society or others);

1 Questions regarding whether or not awards qualify as career development awards should be directed to the AUA Office of Research, see Section VI. Contact Information of this Program Announcement.

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- Have at least two full years remaining on the period of performance for the career development award with

no less than 50% protected time for research (funding is contingent on my maintaining an externally-

funded Career Development Award);

- Be focused on a research project that aligns with one or more of the research priorities described in the AUA’s National Urology Research Agenda (NURA), available at http://www.AUAnet.org/research/national-urology-research-agenda.cfm; and

- Be conducting research within the boundaries of the eight sections of the AUA (http://www.AUAnet.org/about-us/AUA-governance/AUA-sections-and-demographics).

Previous unfunded applicants for Rising Stars in Urology Research Awards are eligible to reapply.

MEMBERSHIP REQUIREMENTS Membership in the AUA is required of recipients of this award. All applicants who are not AUA members at the time of application must commit to applying for AUA membership in the event of being selected to receive a Rising Stars in Urology Research Award. Membership applications must be submitted within one week of accepting the Rising Stars in Urology Research Award and proof of AUA membership must be provided to the AUA Office of Research prior to funds being dispersed via the proposal submission system at https://proposalcentral.com/; additional information about AUA membership can be found at https://www.AUAnet.org/join.

If the research is being conducted in the United States, applicants are not required to be U.S. citizens but must have valid Social Security numbers for Internal Revenue Service purposes.

Neither the Urology Care Foundation nor the AUA Office of Research discriminate as to age, race, color, gender, religion, sexual orientation, disability, citizenship or national origin in the employment and promotion of staff or in the selection of participants in the Rising Stars in Urology Research Award.

D. FUNDING INFORMATION

1. AWARDS AVAILABLE

One award is available for the 2020 Rising Stars in Urology Research Award competition, and it is sponsored by Astellas, Inc.

2. DISTRIBUTION OF FUNDS

During each award year, the Rising Stars in Urology Research Award funds will be paid directly to the awardee (please discuss this with all pertinent individuals at your institutions prior to submitting a Letter of Intent). The Urology Care Foundation does not withhold taxes from award payments (i.e., federal withholding, social security, local or state taxes). It is the responsibility of the awardee to ensure that appropriate federal and local taxes are accounted for. Awards are solely for the purpose of salary supplementation and cannot be used for fringe benefits.

Though the award has a maximum duration of five years, the period of salary supplementation will be commensurate with the period of performance of the existing career development award. Funding starts at $28,000 in year 1 and increases each award year based on the following schedule: year 2, $34,000; year 3, $40,000; year 4, $46,000; and year 5, $52,000. To qualify for subsequent years’ funding, each awardee will be required to meet specific milestones detailed in Section IV.B. Reporting of this Program Announcement. The

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awardee’s eligibility for maintaining the award is also contingent on the awardee maintaining an externally-funded career development award. Under no circumstances should Urology Care Foundation funds be used for fringe benefits, institutional indirect costs, or for salary support for anyone other than the Urology Care Foundation-funded awardee. Note: Awardees may be personally responsible for repayment of funds provided by the award in the event that they fail to meet the obligations of the award described in this Program Announcement.

I I. PREPARATION AND SUBMISSION OF PROPOSAL MATERIALS

A. GENERAL INFORMATION

Applicants are responsible for composing, compiling, and submitting a complete proposal. Each applicant must have a primary mentor for the project. More than one mentor per project is both permitted and recommended if the project is highly translational or multidisciplinary. Each mentor must provide a letter of support and complete the required mentor sections within the Application Agreement Form. Listing consultants or co-investigators on the project is acceptable; the applicant should clearly describe the role of each member of the personnel on the project.

Electronic Registration:

Applicants must go to the 2020 Urology Care Foundation Rising Stars in Urology Research Award program site at http://www.AUAnet.org/research/funding-opportunities/rising-stars-in-urologic-research-award to view all pertinent information regarding the program. Applicants must submit all documents electronically via the

proposal submission system at https://proposalcentral.com/. To prevent emails from the proposal submission system from being identified as spam, it is strongly recommended that all applicants, individuals providing letters of support for the proposal and institutional representatives, add pcsupport@altum.com to their address books or safe sender lists. Applicants requiring technical support related to the grant submission portal should visit https://proposalcentral.com/ and contact Customer Service or send an email to pcsupport@altum.com.

B. LETTER OF INTENT

Applicants are required to complete and submit an electronic Letter of Intent via the proposal submission system at https://proposalcentral.com/ no later than Thursday, May 21, 2020 at 5:00 p.m. Eastern time. Only one Letter of Intent can be submitted per applicant.

Information in the Letter of Intent is not peer reviewed but rather used by the AUA Office of Research to prepare for peer review of proposals. There is no approval process for the Letter of Intent, and applicants should assume that they have permission to submit a full proposal. Applicants are not bound to complete a full proposal upon submitting a Letter of Intent.

Applicants will need to use a proposalCENTRAL profile account which can be created by visiting https://proposalcentral.com/; please make sure that all contact information listed on your profile is up-to-date and to refrain from entering your name in all capitals/All caps. After creating a proposalCENTRAL account and logging into the system, the application process can be accessed by clicking on “Grant Opportunities” (grey tab, top right corner). The American Urological Association’s Rising Stars in Urology Research Award program can then be located and the “Apply Now” link selected.

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Each required Letter of Intent section should be completed as follows: 1. Title Page

Enter the title of your proposal; please refrain from entering the title in all capitals/All caps.

2. Download Templates & Instructions

A Biosketch Example is also provided for reference.

Program Guidelines and Instructions The Program Announcement is provided in this portion of the portal as a reference.

Application Agreement Form This form must be downloaded and completed in its entirety including all necessary signatures

and contact information. Signatures may be signed electronically or by hand. This completed form will be uploaded in “Upload Application Attachments Here” site tab in the portal during submission of the full proposal.

Applicant CV/Biosketch Template A NIH formatted Biosketch Template is provided to be used to create the applicant

CV/Biosketch.

3. Enable Other Users to Access this Proposal

This screen allows you to give other users access to your grant proposal.

4. Applicant/PI

The applicant should click “Edit Professional Profile” to provide the required information; please refrain from entering your name in all capitals/All caps.

Once the applicant clicks “Edit Professional Profile,” he/she will see an orange text box indicating that the “Primary institution is required, please click here to add one.” The applicant should search for and enter the applicant’s current institution. NOTE: Multiple iterations of the institution name may be available, but the name indicated as “Confirmed” in the “Institution Status” column should be selected.

Once the institution has been added, the applicant should click on the orange “Return to LOI/Proposal” button. This button will allow the applicant to toggle between the proposal site tabs of the application and the Professional Profile in order to reference and complete the required information.

Upon returning to the Applicant/PI site tab of the application, the applicant should click the drop down box next to “Principal Investigator” and select his/her name with the newly added institution. This will autofill the “PI Institution” and address information. The applicant should then return to the Professional Profile to complete the remaining required information in the Applicant/PI site tab.

New for 2020: NIH publicly announced that it will start requiring ORCID iD from applicants beginning October 2020 “to simplify applicant reporting and improve the tracking of career outcomes.” (https://grants.nih.gov/grants/guide/notice-files/NOT-OD-19-109.html) Therefore, all applicants will need an ORCID iD to apply for Urology Care Foundation award mechanisms.

5. Eligibility

AUA Membership Status AUA Section Information: All applicants are required to notate the AUA Section in which the

proposed research will be conducted. NOTE: It is imperative that the correct AUA Section be selected as this may impact your funding opportunity options. Applicants should not assume that they are located in an AUA Section based off solely of their state location but should determine the AUA Section by matching their zipcode to those shown for each AUA Section boundary found on the AUAnet.org website e.g. being located in the state of New York

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does not necessarily indicate that one should select the AUA New York Section as some New York zipcodes fall under the AUA Northeastern Section. For more information on AUA Sections and for assistance in selection, visit https://www.AUAnet.org/membership/who-we-are/AUA-sections-and-demographics or call 1-866-746-4282 (toll-free, U.S. only).

Career Development Award Information Please enter in the following information about your Career Development Award:

Status e.g. Pending Funding Source Name e.g. Department of Defense Award Number and Project Title e.g. KKA54692 Positioning of Stents in Pre-pubescent

Patients Funding amount e.g. $108,649 Performance Dates e.g. 07/01/2020 to 07/01/2024

6. Institution & Contacts

Confirm contact information for your institution and institutional representatives.

7. Key Personnel

Enter in the contact information and role for each mentor, the Urology Department Chair, and if applicable, any collaborator that will be providing a Letter of Support for your proposal.

EXAMPLE: If you have three mentors for your application, then you will need to label them mentor 1, mentor 2 and mentor 3. (This site tab of the portal is for the sole purpose of listing your professional relationship title with each person that will be providing a letter of support; It is imperative that you make sure all individuals that are submitting a letter of support are notated here because Peer Reviewers will use the information to identify Conflicts of Interest). If your Urology Department Chair is also your primary mentor, then add that person twice in the system (once for each role). The “Blind Letters of Support” site tab in the portal is where you will notate information of individuals that need to send in a confidential letter of support on your behalf such as your mentor(s) and Urology Department Chair.

8. Blind Letters of Support

The proposal must contain the following Letters of Support listed below on institutional letterhead and should be submitted confidentially via the proposal submission system at https://proposalcentral.com/ by 5:00 p.m. Eastern Time on June 4, 2020: Mentor Letter(s) of Support (two-page limit per individual mentor letter)

The letter(s) of support should describe the applicant’s career development program and the mentor’s specific involvement in and commitment to providing career development and mentorship in urologic research. Specifically, the letter(s) should address the following: Applicant’s characteristics and accomplishments to date, potential for an independent

career in urologic research, and estimated timeline for career development; Mentor’s history of developing early-career investigators; Research environment, including ongoing urologic disease research and how it will

promote the development of the applicant; and Mentor’s plan to support the research project and guide the applicant.

o PLEASE NOTE: If a letter of support from the primary mentor is missing, the proposal cannot be considered.

Letter of Support from Urology Department Chair (two-page limit) The letter of support from the Urology Department Chair documenting should state support for the applicant, with emphasis on the amount of and commitment to protected

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time for research. If your Urology Department Chair is also your primary mentor, then they have the option to submit one combined letter of support on your behalf.

Enter the contact information for each Mentor(s), and Urology Department Chair to enable them to submit their confidential Letters of Support. NOTE: The “Phone” and “Effort” fields in the table should be disregarded). It is highly recommended that the applicant makes sure that the individuals providing Letters of Support have added pcsupport@altum.com to their address books or safe sender lists to receive emails from the submission system PRIOR TO adding their name on the “Blind Letters of Support” site tab in the portal.

Any email address listed here will receive an email notification from proposalCENTRAL with a link to submit a Letter of Support. ***This link will expire: 05/21/2020 5:00:00 PM (US Eastern Time)***. If they are unable to submit the Letter of Support before the link expires, then the applicant should send another e-mail notification request from proposalCENTRAL.

To send another email notification request to a person submitting a Letter of Support, click the envelope symbol hyperlink found on the right-hand side of the screen of the “Blind Letters of Support” site tab in the portal.

All applicants are responsible for contacting these individuals and making sure that all letters of support are uploaded into the proposal portal system by the proposal deadline: June 4, 2021 at 5:00 p.m. Eastern Time.

NOTE: Applicants do not need to put email addresses for collaborator(s) in this portion of the portal since letters of support from collaborators do NOT need to be submitted confidentially. Letters from the Collaborator(s), if applicable, should be sent directly to the applicant, who will upload the letter with the full application, see Section II.C. under “Item 7. Letters of Collaboration” of this Program Announcement for more information.

9. Project Information

Lay Statement The “Lay Statement” should briefly summarize (3-5 sentences) the proposed research project

in language that can be understood by audiences WITHOUT a background in science or medicine. By providing this information, the applicant thus gives permission for its use on the Urology Care Foundation website, www.UrologyHealth.org, and the AUA website, www.AUAnet.org, and in press releases and other promotional materials for the Rising Stars in Urology Research Award program.

Technical Project Description The “Technical Project Description” should briefly summarize the proposed project using any

necessary scientific terminology or procedures. Research topic(s) and Keywords

Enter the research topics and keywords relevant to your proposal. Weighting %: Please notate the percentage that your project will focus on each urologic

organ of interest, disease(s) of study, research area classification, and selected proposal type.

10. Validate

This portion of the portal will check for any missing REQUIRED information or files. All missing required information will be listed on the screen. Please correct any missing information before proceeding to submit your Letter of Intent.

11. Preview Letter of Intent

NOTE: Signature of the title page by the PI/chairman/signing official is not required. This guidance which is shown in the proposal submission system should be disregarded.

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12. Submit

After submitting the Letter of Intent, the proposal submission system will send an email to the individuals listed in “8. Blind Letters of Support” site tab in the portal requesting that they submit a letter of support for the proposal prior to the full application deadline.

Please delete any unfinished Letter of Intent drafts/versions from the system.

C. PREPARATION AND SUBMISSION OF THE PROPOSAL PACKAGE

After administrative review of the Letter of Intent, the AUA Office of Research will open the submission portal to allow the applicant to submit his/her full proposal (You will receive an email from proposalCENTRAL when you have been granted access to the full proposal). Prepare and submit the proposal package to include all documents as indicated below. Each component must adhere to its specific page limitation as indicated below as well as use a header to signify each section listed below.

PLEASE NOTE: Any components that exceed their respective page limits will be removed from the application or

administratively truncated. Each required proposal section should be completed as follows:

1-9. Title Page, Download Templates, Enable Other Users to Access this Proposal, Applicant/PI, Institution & Contacts, Key Personnel, Blind Letters of Support and Project Information

The information shown in sections 1-9 will be pre-populated with the same information already provided in the Letter of Intent.

10. Other Research Support

Submit information on the applicant’s other existing and/or pending funding support, if any.

11. Assurances & Certifications

If the proposed study involves human subjects and/or vertebrate animals, provide IRB and/or IACUC approval/exemption information, if available at the time of application.

12. Upload Application Attachments Here

The applicant must prepare the following components of the application as PDF files with each component adhering to its specific page limitation as indicated below as well as use a header to signify each section listed. NOTE: Pages in excess of the limitation for any component will be removed from the application. If the Applicant CV/Biosketch, Mentor Letter of Support, or Mentor Biosketch is missing, the application will not be reviewed. Item 1: Application Agreement Form

Download and complete the Application Agreement Form found on the AUA website at http://www.AUAnet.org/research/funding-opportunities/rising-stars-in-urologic-research-award; it is also available in the portal on the “Download Templates & Instructions” tab. This form must be completed in its entirety, including all necessary signatures and Grant Administrator contact information. Please type the information entries; illegible information will not be accepted.

Item 2: Applicant Career Plan (one-page limit)

The statement of career goals and plans should include description of any coursework, conferences, seminars, teaching or clinical responsibilities, grant writing, mentoring, or other activities or training that the applicant plans to use in his or her near-term urologic research career development. In addition, applicants should describe longer-term goals (10-15 years post-award) for their careers.

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Item 3: Applicant CV/Biosketch (five-page limit) Include the applicant’s updated biosketch (five pages, NIH-style2 required).

Item 4: Career Development Award (and Previous Rising Stars Application, if applicable) Peer Review Summary Statement (including Scores)2 Provide a copy of the peer review summary statement (including scores) received for the existing career development-type award (no page limit).

Item 5: Career Development Award Application2 (no page limit) Provide a copy of the application submitted for your career development-type award. This should be the entire application as originally submitted, including all components (e.g., project description, biosketches, budget).

Item 6: Career Development Award Notification Letter3 (no page limit) Provide a copy of the award notification letter for the existing career development-type award. This will serve as documentation of the receipt of the required award and should indicate the award period of performance.

Item 7: Letters from Collaborator(s), (two-page limit per letter; only if applicable) In addition, it is recommended that a letter of support be included from any collaborator(s) on the project, if applicable. These letters are not submitted confidentially and should be submitted by the

applicant via the proposal submission system.

Item 8: Letters of Support (Blind) The proposal must contain one letter of support on institutional letterhead from each mentor and the Urology Department Chair, which must be sent confidentially via the application portal system at https://proposalcentral.com/ prior to the proposal submission deadline on June 4, 2020 at 5pm Eastern Time. While applicants will not be able to view the submitted letters in the proposal submission system, the applicant may use the system to view verification that the letters have been received.

Item 9: Mentor Biosketch(es) (five-page limit per person)

Include a biosketch for each mentor (five pages each, NIH-style3 required). These should be versions updated from those submitted for the original career development award.

Item 10: Relevance Statement (one-page limit) Provide a statement from the applicant explaining relevance of the research project to the NURA research priorities. The NURA can be accessed at http://www.AUAnet.org/research/national-urology-research-agenda.cfm.

Item 11: Research Project Abstract (one-page limit) Briefly summarize the following elements of the proposed research project and training; and use each listed below as a heading:

1. Problem to Be Addressed 2. Specific Aims and Experimental Design 3. Mentoring Plan

2 OMB No. 0925-0046

3 Career Development Award notifications, applications, and summary statements and scores are confidential documents that the applicant must choose to disclose. However, these items are required for this competition and will be kept confidential by the AUA Office of Research and Urology Care Foundation.

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4. Potential Impact of Project on Urologic Research And on the Applicant’s Career Development

13. Validate This portion of the portal will check for any missing REQUIRED information or files. All missing required information will be listed on the screen. Please correct any missing information before proceeding to submit your full proposal. 14. Print Full Application with Uploads 15. Submit

PLEASE NOTE: The AUA Office of Research strongly recommends that, prior to submission, all applicants send their proposals through both institutional scientific review (where available) and appropriate institutional grant administration review at their home institutions to optimize grant quality and ensure consistency with institutional policies.

The proposal must be submitted electronically at https://proposalcentral.com/ no later than Thursday, June 4, 2020 at 5:00 p.m. EASTERN TIME. Applicants should allow ample time for composing, compiling, and submitting materials. Late applications or those not submitted through the proposal submission system will NOT be considered.

I II. PROPOSAL REVIEW INFORMATION

A. PROPOSAL REVIEW AND SELECTION PROCESS

All proposals are evaluated by a peer review panel of expert physician-scientists and researchers. Each proposal is considered according to established criteria for determining merit as described below.

Following the completion of peer review and from the pool of applications deemed fundable, available awards will then be matched to the available award(s). All funding decisions must be approved by the AUA Director of Research and Research Council Chair. All review processes are conducted confidentially to maintain the integrity of the selection process. Peer review panel members sign a nondisclosure statement that all proposal and evaluation information will not be disclosed outside the peer review panel. Violations of confidentiality can result in the voiding of peer review results and other corrective actions. In addition, the applicant, mentor(s), and other individuals involved in or otherwise standing to benefit from the proposal’s funding are prohibited from contacting persons involved in the review process to gain protected evaluation information or to influence the evaluation process. Violations of these prohibitions will result in the disqualification of the application.

B. REVIEW CRITERIA

All proposals will be evaluated against the following review criteria:

Applicant

To what degree the applicant’s achievements (as reflected by awards, honors, publications, promotions, regional/national presentations, etc.) indicate his or her potential to make significant contributions to the chosen field of urologic research and build a successful career as a leading scientist in urologic research.

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To what degree the applicant’s stated career goals and letters of support indicate a strong commitment to pursuing urologic disease research throughout his or her career.

Whether the applicant’s proposed level of effort is appropriate for successful career development, completion of the proposed work, and time to build the necessary aspects of an early independent research program.

Mentor(s)

To what degree the mentor or mentoring team demonstrates a strong commitment to the applicant’s career development, with a well-developed mentoring plan.

To what degree the mentor or mentoring team has the required expertise and track record, in relation to urologic disease research, to provide sufficient scientific guidance and oversight for the research project and career development.

To what degree the mentor or mentoring team has a training record that includes past/current trainees that have successfully transitioned to career independence.

Research Project

To what degree the project is highly meritorious, i.e., innovative, significant, and timely, as demonstrated by the career development award application and previous peer review critiques and scores.

To what degree the project addresses a priority area of research according to the NURA.

To what degree the proposed research will be driven by the applicant with guidance only as needed from the mentor or mentoring team.

To what degree the proposed research will help the applicant transition into a more advanced academic position.

To what degree the proposed project is likely to interface with different scientific disciplines and significantly influence and advance the field of urologic research.

Institution

To what degree the institution provides a supportive, well-resourced environment with clear evidence of adequate protected time for research to promote the development of the applicant.

C. NOTIFICATION OF PROPOSAL REVIEW RESULTS

Rising Stars in Urology Research Award applicants will be notified of funding decisions via the proposal submission system and/or in writing via email no later than August 2020; results will not be given over the phone. To prevent emails from the proposal submission system from being identified as spam, it is strongly recommended to add pcsupport@altum.com to your address book or safe sender list. Summary statements of proposal reviews will not be provided for the Rising Stars in Urology Research Award program.

Applicants selected for funding must: 1. Send an email to grantsmanager@AUAnet.org to confirm or refuse the funding within 24 hours. 2. Confirm AUA membership within a week of being notified of your funding status:

a. Submit proof that their AUA membership is active into proposalCENTRAL

b. If the applicant is not already an AUA member, then the applicant will need to apply for membership and submit proof of your application via proposalCENTRAL (screenshots of submitted/confirmed applications are acceptable).

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3. Ensure that the correct individuals are listed to have access to your award in proposalCENTRAL e.g. institutional representatives.

4. Submit a high-quality photo in professional attire (see Section III.C. under “Photographs for UrologyHealth.org and AUAnet.org” shown in the paragraph below for more detailed instructions).

Photographs for UrologyHealth.org and AUAnet.org For applicants selected for funding, a headshot photograph saved as a jpeg file must be submitted electronically via the proposal submission system at https://proposalcentral.com within 24 hours of receiving a notification email from the proposal submission system and/or the AUA Office of Research (save the file as, “Last name, First name_Photo” e.g., “Smith, John_Photo”). The photograph should be a high-quality headshot (file size typically ≥1MB) with either professional dress or a laboratory/white coat. Please do not compress the photograph after it is taken. With the submission of the photograph, the applicant thus gives permission for his/her photo to be used in press releases and other promotional materials for the program. The photograph will not be shared with reviewers and will not impact the review process or funding decisions.

D. NOTICE OF AWARD

For applicants selected for funding, a Notice of Award letter will be issued prior to the first payment to notify the awardee, the mentor(s), and the institution that an award has been made and to specify the terms and conditions of the award.

IV. AWARD REQUIREMENTS

All Urology Care Foundation Rising Stars in Urology Research Award recipients must adhere to the following

requirements:

A. REGULATORY APPROVALS AND EXEMPTIONS

Institutional Review Board (IRB)

If activities involving human subjects are planned during the proposed research, the applicant must provide a letter of approval or exemption from the local IRB. IRB letters of approval or exemption are not required at the time of application submission. Should the application be selected for funding, the award will be contingent upon receipt of a copy of the current IRB approval or exemption letter by the Urology Care Foundation. If IRB approval or exemption for the project is not obtained within 90 days of the award performance period start date, the Urology Care Foundation reserves the right to terminate the award.

Institutional Animal Care and Use Committee (IACUC)

If activities involving vertebrate animals are planned during the research, the applicant must submit a letter of approval or exemption by the IACUC. IACUC letters of approval or exemption are not required at the time of application submission. Should the application be selected for funding, the award will be contingent upon receipt of a copy of the current IACUC approval or exemption letter by the Urology Care Foundation. If IACUC approval or exemption for the project is not obtained within 90 days of the award performance period start date, the Urology Care Foundation reserves the right to terminate the award.

B. REPORTING

The Rising Stars in Urology Research Award includes the reporting requirements described below. Failure to adhere to reporting requirements and/or provide appropriate documentation may result in a delay in payments, termination of the award, and/or suspension of the awardee, mentor, or institution from eligibility for subsequent Urology Care Foundation funding opportunities. Unless approved by the institution and the Urology Care

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Foundation, failure to complete the duration of the research period may result in repayment of funds to the Urology Care Foundation.

1. PROGRESS REPORTS AND PERSONAL STATEMENTS

Awardee Report

By July 31 of each funding year after the first six months of Urology Care Foundation funding, awardees must submit an interim progress report and personal statement via proposalCENTRAL. The report must be submitted to the AUA Office of Research and follow the guidance provided in the Notice of Award. Each year of funding is contingent upon receipt of a satisfactory progress report for the previous year.

In addition, within 60 days of the end of the funding period, the awardee must submit a Final Progress Report to the AUA Office of Research following the guidance given in the Notice of Award.

Mentor Report

Under separate cover, the primary mentor must submit a confidential statement electronically via proposalCENTRAL evaluating the awardee’s performance and detailing career development progress in addition to any other information as outlined in the Notice of Award.

2. POST-AWARD REPORTING

At specified time points following the completion of the Urology Care Foundation award (approximately three, five, and 10 years post-award), the AUA Office of Research will contact previous awardees to collect additional award outcomes information including, but not limited to, publications, funding, invited speakerships and presentations, mentorship, and leadership positions within the AUA or affiliated organizations.

The Urology Care Foundation and the AUA Office of Research request that all past awardees provide updated contact information when appropriate and be responsive to requests for post-award information.

C. CAREER DEVELOPMENT AWARD REQUIREMENTS

Each Rising Stars Award recipient is required to develop a grant application for funding as an independent investigator (e.g., NIH R01 or R21, DoD Idea Development Award), no later than the fourth or penultimate funding year of the Rising Stars Award, to be submitted to the NIH, DoD, VA, or other funding agency no later than the first quarter of the fifth or final funding year.

Milestones have been developed to assess progress over the period of performance. Progress will be evaluated annually. If annual milestones are not reached, the awardee risks becoming ineligible for further support or may be withdrawn from the program. The milestones are:

Years 1–5:

o Submit progress reports on July 31 of each funding year after the first six months of Urology Care Foundation funding.

o Attend the annual interview (typically conducted during the AUA Annual Meeting) and provide requested information including an annual interview questionnaire in a timely manner.

o Attain timely achievement of career development objectives and research specific aims described in the career development grant, or provide justification for any variances.

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Penultimate Year: To be eligible for the final year of funding, the awardee must develop an application for funding as an independent investigator (e.g., NIH R01 or R21, DoD Idea Development Award) no later than the fourth or penultimate funding year. The expectation is that the application developed for funding as an independent investigator would be submitted to the funding agency no later than the first quarter of the fifth or final funding year.

Remain in academic practice for a minimum of the number of years equal to the number of years of support provided. If this obligation is not met, repayment of the award, in an amount to be determined at the exclusive discretion of the Urology Care Foundation, may be required.

D. UROLOGY CARE FOUNDATION RESEARCH-RELATED ACTIVITIES

Each year, the AUA and the Urology Care Foundation coordinate several events designed to advance urologic research and provide educational venues, especially for early-career investigators. The AUA Office of Research also provides opportunities for funded investigators to present posters at several of these events. For all investigators funded by the Urology Care Foundation Rising Stars in Urology Research Award, attendance is required, with some exceptions as described below. Unless prior approval is given, failure to attend an event may disqualify the awardee from receiving a future Urology Care Foundation award or payment. Travel awards or other means of travel support may be available for some events; also see Section V. Urology Care Foundation Scholar Travel Support Program of the Program Announcement for more information about the Scholar Travel Support Program.

1. AUA ANNUAL MEETING EVENTS

Urology Care Foundation Research Honors Program and Reception: All current Urology Care Foundation funded investigators are acknowledged at this program. Attending the program and presentation of a poster is required for all individuals receiving funding from the Urology Care Foundation.

Basic Sciences Symposium: This symposium is a premier research event attracting basic and translational researchers and physician-scientists from various specialties. Past program topics include stem cells and nanotechnology, inflammation and fibrosis, new perspectives in pelvic health, and aging and urologic manifestations. Attendance is required if the topic is associated with the research being conducted by the awardee.

Urologic Oncology Research Symposium: The intent of this symposium is to create synergies and foster collaboration in genitourinary oncology by bringing together scientists and clinicians at all career levels in a stimulating and interactive setting. The information discussed and shared during this meeting is expected to catalyze the translation of laboratory research to practical application. It is also intended to serve as a forum where early-career investigators can interact with leaders in a host of disciplines related to urologic cancers. Attendance is required if the topic is associated with the research being conducted by the awardee.

AUA Research Forum – Funding Opportunities and Grant Writing Workshop: Typically each year, the AUA Office of Research offers an educational course/forum to assist researchers in identifying and understanding sources of funding and skills needs for successful grant writing. The forum provides information on major funding opportunities, preparing an effective grant application, and peer review processes. Representatives from public (e.g., federal) and private (e.g., foundations, societies) funding organizations are typically in attendance to provide information on current opportunities. All investigators funded by the Urology Care Foundation are required to attend the session if it is offered.

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AUA Research Forum – Early-Career Investigators Showcase: This event provides a venue showcasing the research of promising early-career investigators. The program features presentations on innovative, relevant, and potentially impactful research studies that are of great interest to the basic, translational and clinical research communities. A panel of judges scores the presentations and awards are provided to the top three presenters. All investigators receiving funding from the Urology Care Foundation are required to attend this event.

Early-Career Scientists Exchange: Held every other year, this event brings together Urology Care Foundation awardees with representatives from the AUA Office of Research and funding organizations in an informal setting to discuss research career challenges and strategies for success. Attendance is required at the discretion of the AUA Office of Research.

2. EVENTS AT AUA HEADQUARTERS

AUA Co-Sponsored Research Symposia: The AUA Office of Research often co-sponsors research symposia and workshops with other urology sub-specialty societies and research institutions that cover the spectrum of urologic disease (e.g., AUA/SBUR Summer Research Conference, Diabetes and Diabetic Uropathy Symposium). Attendance to these meetings is optional but strongly encouraged if the research topic is relevant to the funded research award.

Early-Career Investigators Workshop: The goal of this workshop is to motivate and support early-career researchers and surgeon-scientists by providing an outstanding program of mentoring, career development, and scientific perspectives presented by leaders in the field. The program agenda typically includes information and interaction with representatives from public and private funding organizations, a mock scientific peer review panel/study section, and faculty presentations on research success and career development. Attendees preparing to submit grant applications for independent research or career development funding also participate in working sessions that provide 1-on-1 instruction from faculty advisors with concrete guidance for improving current or developing grant applications, as well as roundtable discussions with experts on federal funding opportunities. Attendance is strongly recommended but not required.

E. PUBLICATION ACKNOWLEDGEMENTS

Awardees are required to send the AUA Office of Research electronic copies of articles published based on their Rising Stars in Urology Research/Career Development Award-funded research. Any publication or presentation arising from work supported in whole or in part by the Urology Care Foundation should include the following acknowledgment:

“This work was supported in part by the Urology Care Foundation Rising Stars in Urology Research Award Program and [SPONSOR NAME].”

In addition, it is suggested that awardees add “2020 Urology Care Foundation Rising Stars in Urology Research Awardee” to their email signature blocks.

F. CHANGES TO PROJECT, PERSONNEL, INSTITUTION, OR FUNDING

Any changes in the research project, mentor(s), personnel, or location/contact information that occur after the application is selected for funding or during the award period must be reported to and approved by the AUA Office of Research. Changes in PI (i.e., the Rising Stars in Urology Research Award recipient) will result in award termination.

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If the awardee is selected for any additional funding from organizations other than the Urology Care Foundation after being selected for a Urology Care Foundation award, the awardee MUST contact the AUA Office of Research to discuss appropriate courses of action. If the awardee does not meet this requirement, return of any used or unused Urology Care Foundation funds may be required.

V. UROLOGY CARE FOUNDATION SCHOLAR TRAVEL SUPPORT PROGRAM

The Urology Care Foundation Scholar Travel Support Program, administered by the AUA Office of Research, is intended to provide opportunities for investigators funded through the Urology Care Foundation research award programs to attend scientific/professional meetings relevant to basic, translational and clinical research in urology. This program provides travel support (maximum of $1,5004 per award year, with a maximum of $1,000 per meeting) to Rising Stars in Urology Research Award recipients upon the review and approval of the Scholar Travel Support Program application request. This program is not intended to serve as the sole source of travel funding for award recipients, but rather to provide supplemental travel funds to those provided by travel awards and the award recipient’s host institution, especially when funds are needed for the award recipient to attend the meetings required by our award programs. Award recipients must plan usage of the funds so they have some funds available if needed to attend all of the required meetings mentioned in Section I.D. under “Distribution of Funds” of this Program Announcement as a higher priority above other scientific meetings.

New for 2020: Scholar Travel Support Program funds will be allowed to cover family care while traveling expenses. This expense allowance is aimed at removing travel-related barriers to the professional advancement of grantees. It is not intended for everyday caregiving services, but for those extraordinary expenses specifically related to grantee travel to essential scientific meetings (see the Scholar Travel Support Application and/or Notice of Award letter for more information about eligible family care while traveling expenses and restrictions).

For more information in regards to the Scholar Travel Support Program, contact Research Program Specialist, Idrissa Heard, iheard@AUAnet.org.

VI. CONTACT INFORMATION

Questions related to this Program Announcement or submission requirements should be directed to the AUA Office of Research.

Assistance is typically available Monday through Friday from 8:00 a.m. to 5:00 p.m. Eastern time. Response times may vary depending upon the volume of inquiries.

The preferred method of communication is email to grantsmanager@AUAnet.org. Phone calls, when necessary, can be directed to 410-689-3945.

4 The funds provided from the Scholar Travel Support Program are in addition to the funds described in Section I.D. under

“Distribution of Funds” of this Program Announcement i.e. awardees will receive $20,000 per year plus $1500 in travel support.