2019: Pivoting to Offense - Bausch Health/media/Files/V/Valeant-IR/reports-and-presentations/...Jan...
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2019: Pivoting to Offense 37th Annual J.P. Morgan Healthcare Conference Jan. 7, 2019
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This presentation contains forward-looking information and statements, within the
meaning of applicable securities laws (collectively, “forward-looking statements”),
including, but not limited to, statements regarding the Company's future prospects
and performance, anticipated market trends and opportunities, planned dermatology
growth, anticipated revenue from our Significant Seven products (including in 2019),
the expected impact on long-term growth of new product approvals (including
approvals of the Significant Seven), the anticipated submission, approval and launch
dates for certain of our pipeline products and R&D programs, the anticipated timing
of commencement of studies or other development work of our pipeline products and
R&D programs, the anticipated closing of certain of our pending acquisitions, the
planned implementation of our new access model for our Ortho Dermatologics
business and the anticipated impact of such new model on such business, the
planned expansion and expanded launches of certain of our products and
businesses, anticipated line extensions for certain of our products, our ability to make
additional debt repayments, expected total company revenue growth for 2019, the
amount of expected cash generated from operations and the anticipated use thereof,
expected R&D investment growth in 2019, our ability to continue to improve
operational efficiency and the expected impact thereof, expected revenue and
adjusted EBITDA (non-GAAP) growth, the Company’s mission (and the elements
and timing thereof) and the Company’s plans, goals and expectations for 2019 and
beyond and our ability to achieve such goals, plans and expectations. Forward-
looking statements may generally be identified by the use of the words "anticipates,"
"expects," “goals”, "intends," "plans," "should," "could," "would," "may," "will,"
"believes," "estimates," "potential," "target," “commit,” “tracking,” or "continue" and
variations or similar expressions. These forward-looking statements, including
management’s plans, goals and expectations for 2019 and beyond, are based upon
the current expectations and beliefs of management and are provided for the
purpose of providing additional information about such expectations and beliefs and
readers are cautioned that these statements may not be appropriate for other
purposes. These forward-looking statements are subject to certain risks and
uncertainties that could cause actual results and events to differ materially from
those described in these forward-looking statements. These risks and uncertainties
include, but are not limited to, the risks and uncertainties discussed in the Company's
most recent annual and quarterly reports and detailed from time to time in the
Company's other filings with the Securities and Exchange Commission and the
Canadian Securities Administrators, which risks and uncertainties are incorporated
herein by reference. In addition, certain material factors and assumptions have been
applied in making these forward-looking statements (including the plans, goals and
expectations for 2019), including that the risks and uncertainties outlined above will
not cause actual results or events to differ materially from those described in these
forward-looking statements, and additional information regarding certain of these
material factors and assumptions may also be found in the Company’s filings
described above. The Company believes that the material factors and assumptions
reflected in these forward-looking statements are reasonable, but readers are
cautioned not to place undue reliance on any of these forward-looking statements.
These forward-looking statements speak only as of the date hereof. The company
undertakes no obligation to update any of these forward-looking statements to reflect
events or circumstances after the date of this presentation or to reflect actual
outcomes, unless required by law.
Forward-Looking Statements
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To supplement the financial measures prepared in accordance with U.S. generally
accepted accounting principles (GAAP), the Company uses certain non-GAAP
financial measures including Organic Revenue Growth and Adjusted EBITDA.
Management uses these non-GAAP measures as key metrics in the evaluation of
Company performance and the consolidated financial results and, in part, in the
determination of cash bonuses for its executive officers. The Company believes
these non-GAAP measures are useful to investors in their assessment of our
operating performance and the valuation of our Company. In addition, these non-
GAAP measures address questions the Company routinely receives from analysts
and investors and, in order to assure that all investors have access to similar data,
the Company has determined that it is appropriate to make this data available to all
investors.
However, these measures are not prepared in accordance with GAAP nor do they
have any standardized meaning under GAAP. In addition, other companies may use
similarly titled non-GAAP financial measures that are calculated differently from the
way we calculate such measures. Accordingly, our non-GAAP financial measures
may not be comparable to similar non-GAAP measures. We caution investors not to
place undue reliance on such non-GAAP measures, but instead to consider them
with the most directly comparable GAAP measures. Non-GAAP financial measures
have limitations as analytical tools and should not be considered in isolation. They
should be considered as a supplement to, not a substitute for, or superior to, the
corresponding measures calculated in accordance with GAAP.
Further information about these non-GAAP measures, as well as the reconciliations
of these historic non-GAAP measures to the most directly comparable financial
measures calculated and presented in accordance with GAAP, can be found in the
appendix here and, together with other information relating to these non-GAAP
measures, in the Company’s third quarter 2018 (3Q18) earnings presentation, which
can be found on the Company’s website at
https://ir.bauschhealth.com/~/media/Files/V/Valeant-IR/reports-and-
presentations/3q18-bausch-health-earnings-presentation.pdf.
However, the Company does not provide reconciliations of projected Adjusted
EBITDA (non-GAAP) to projected GAAP net income (loss), due to the inherent
difficulty in forecasting and quantifying certain amounts that are necessary for
such reconciliations. In periods where significant acquisitions or divestitures are
not expected, the Company believes it might have a basis for forecasting the
GAAP equivalent for certain costs, such as amortization, that would otherwise
be treated as a non-GAAP adjustment to calculate projected GAAP net income
(loss). However, because other deductions (e.g., restructuring, gain or loss on
extinguishment of debt and litigation and other matters) used to calculate
projected net income (loss) may vary significantly based on actual events, the
Company is not able to forecast on a GAAP basis with reasonable certainty all
deductions needed in order to provide a GAAP calculation of projected net
income (loss) at this time. The amounts of these deductions may be material
and, therefore, could result in GAAP net income (loss) being materially different
from (including materially less than) projected Adjusted EBITDA (non-GAAP).
Non-GAAP Information
New Product Launches
0
2018 Accomplishments
0 Organic revenue
growth1,2 generated YTD as of 9.30.2018
compared to YTD 9.30.2017
2% 0
debt repaid with cash generated from
operations during 2018
>$1B
Name Change
0 Dr. Andrew C. Von Eschenbach
Resolution of Key Legacy Issues
Achieved dismissals or other positive outcomes in resolving litigation, disputes and investigations in approximately 60 matters as of Nov. 7th, 2018
• Resolved XIFAXAN® IP litigation: Preserved market exclusivity until 20283 with no financial payments made by BHC
• Resolved Salix SEC investigation with no monetary penalty4
• Resolved Allergan securities litigation
• Resolved outstanding arbitration with Alfasigma S.p.A.
1. See Slide 3 for further non-GAAP information. See our 3Q18 earnings presentation for GAAP reconciliation and other non-GAAP information at https://ir.bauschhealth.com/~/media/Files/V/Valeant-IR/reports-and-presentations/3q18-bausch-health-earnings-presentation.pdf.
2. Organic growth, a non-GAAP metric, is defined as an increase on a year-over-year basis in revenues and/or operating results on a constant currency basis (if applicable) excluding the impact of divestitures and discontinuations.
3. Actavis will be able to begin marketing the medicine earlier if another generic rifaximin product is granted approval and starts selling or distributing such generic rifaximin product before Jan. 1, 2028.
4
(SiHy Daily)
Bausch + Lomb ULTRA® Multifocal for Astigmatism
5 5
4. Subject to approval by the U.S. District Court for the Southern District of New York. 5. Co-promotion arrangement with third party.
New Board Member
5
• Bausch + Lomb/International and Salix are driving the pivot to offense
• 76% of the total company generated 6% organic revenue growth1,2 (YTD as of 9.30.2018)
Bausch + Lomb/International 55%
Salix 21%
Ortho Dermatologics 8%
Diversified Products 16%
Global Vision Care Global Surgical Global Consumer Global Ophtho Rx International Rx
+7%
+3%
+3%
+4%
0%
55% of total company generated 3% organic
revenue growth1,2 YTD as of 9.30.2018
21% of total company generated 16% organic
revenue growth1,2 YTD as of 9.30.2018
1. See Slide 3 for further non-GAAP information. See also Appendix and our 3Q18 earnings presentation at https://ir.bauschhealth.com/~/media/Files/V/Valeant-IR/reports-and-presentations/3q18-bausch-health-earnings-presentation.pdf for GAAP reconciliation and other non-GAAP information.
2. Organic growth, a non-GAAP metric, is defined as an increase on a year-over-year basis in revenues and/or operating results on a constant currency basis (if applicable) excluding the impact of divestitures and discontinuations.
Bausch Health: Pivoting to Offense
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Myopia Epidemic
Disease Progression
Myopia rates are steadily increasing,
especially in Eastern Asia
Fully Integrated Eye Health Business…
…Driven by Megatrends and New Products
Rate of Myopia in Hong Kong
Based on Birth Year3
Environmental Factors Affecting Myopia
• Academic pressure: Studies show that myopia
increases in proportion to time spent studying3
• Lack of outdoor activities: Studies suggest that
every 40 minutes of outdoor activity per day
decreases the chances of developing myopia by
9%3
• Increased screen time: U.S. adults spend
nearly half a day—over 11 hours—listening to,
watching, reading or generally interacting with
media4
Myopia is a risk factor
for glaucoma, macular
degeneration and
retinal detachment3
~1.3B
people globally living
with some form of vision
impairment1
80%
of all vision impairment
globally is considered
avoidable1
8x
In the U.S., individuals 65
and over use 8x more eye
care products vs. those
younger than 652
1. https://www.who.int/news-room/fact-sheets/detail/blindness-and-visual-impairment. 2. Internal estimates and https://www.preventblindness.org/sites/default/files/national/documents/Future_of_Vision_final_0.pdf. 3. https://www.scmp.com/magazines/post-magazine/long-reads/article/2085125/chinas-myopia-epidemic-why-simple-solution-being. 4. https://www.nielsen.com/content/dam/corporate/us/en/reports-downloads/2018-reports/q1-2018-total-audience-report.pdf.
30%
70%
87%
0%
25%
50%
75%
100%
Pre-1950 1950-1980 Post 1997
Shift Occurring in the Global Contact Lens Market1
• Replacement Frequency: Daily accounts for ~50% of the
market and is growing across major markets, including U.S.,
Japan, EU, Asia-Pacific and Latin America
Bausch + Lomb’s Current Market Position
• U.S. Market: Growth leader in the U.S. contact lens market;
exceeded category growth rates for 5 consecutive quarters1
• International Market: Bausch + Lomb is the leader (#1) in
key emerging markets (China, Thailand and India), which
represent ~40% of the world’s population and are the fastest
growing markets4
0% 5% 10% 15%
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Global Vision Care: Offerings for a Shifting Market
1. Third party data on file and internal estimates. 2. Gallup study of the US multi-focal market, October 2015. 3. Internal estimates. 4. CLI, Euromonitor and internal estimates. 5. YTD 2018 through 12/2/2018.
Market Dynamics and Position
+4-5%
+13%
Industry
U.S. Contact Lens Market Growth in 20181
Continued R&D Investment Drives 2019 Pipeline Expansion
• Bausch + Lomb ULTRA® Multifocal for Astigmatism launch planned for
2019; expected to address the >30M under-served astigmatic
presbyopes in the U.S.2
• Continued expansion for daily disposable parameter offerings
• Specialty Vision Products: Zen Multifocal (2019), Tangible Science
Hydra-PEG® coating (2019) and Custom Soft Contact Lenses (2020)
Key Products that Serve the
Changing Landscape
• Daily disposable contacts with patented
dehydration barrier, allowing lens to maintain
~100% of its moisture for a full 16 hours3
• Fastest growing full family of daily disposable
contact lenses in the U.S.1,5
• Monthly disposable contacts engineered to
provide all-day comfort and consistently clear
vision
• Fastest growing full family of frequent
replacement contact lenses in the U.S.1,5
• Daily disposable contacts with silicone hydrogel
material with the Moisture Seal™ Technology
• Launched in Japan (Sept. 2018); SiHy daily
launch planned for U.S. (2020) (SiHy Daily)
Leader in Eye Vitamin Growth
• AMD is the leading cause of blindness in the United States for
people over 653,4
• As baby boomers reach age 65 and beyond, millions of people
are at risk for AMD4
• Estimated 18M will have macular degeneration by 20505
• Out of those diagnosed with moderate-to-advanced AMD, only
26% of people are using an AREDS vitamin8
New Product: Ocuvite® Blue Light Vitamins
• Most adults spend seven or more hours daily in front
of digital devices, exposing themselves to blue light
for an extended period of time
• Ocuvite® Blue Light eye vitamins contain 25
milligrams of lutein and five milligrams of zeaxanthin
isomers, the key eye nutrients that help absorb blue
light before it reaches the macula
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1. IQVIA ProVoice Monthly Survey Month Ending Sept. 2018. 2. Retail dollar share for total US (MULO) for the week ending December 23rd, 2018, according to IRI and One Click Retail. 3. Bressler NM. Age-related Macular Degeneration is the leading cause of blindness: [Commentary by Neil M. Bressler, MD].
JAMA. 2004;291(15):1900–1901. 4. Friedman DS, O’Colmain BJ, Muñoz B, et al; for The Eye Diseases Prevalence Research Group. Prevalence of age-related
macular degeneration in the United States. Arch Ophthalmol. 2004;122(4):564–572. 5. Jordan, Serena. Nearly 18 Million Will Have Macular Degeneration by 2050. But newer treatments could reduce related
blindness by 35%. HealthDay. USNews.com/Health. 4/2009.
Global Consumer: New Products to
Address Eye Care
LUMIFY™ is the only over-the-counter eye
drop with low-dose brimonidine for the
treatment of eye redness
• 95% symptom improvement at one
minute
• Reduced redness for up to eight hours
Consumer Reaction
• #1 physician-recommended product in
the Redness Reliever category1
• Achieved a weekly market share of
~25%2
Age-related Macular Degeneration (AMD)
Ocuvite®: Supplements for Eye Health
Eye Redness Treatment
Preservative-Free Formula for Dry Eye Symptom Relief
• Dry eye is one of the most common eye conditions
in the U.S., affecting more than 140M Americans6
• Up to 86% of dry eye cases are caused by
Meibomian Gland Dysfunction7, a condition that
compromises the lipid layer in the eye and affects
the eye's ability to produce oils that coat natural
tears
• Soothe XP uses a unique combination of
Restoryl® mineral oils as active ingredients,
which work to restore the lipid layer, seal in
moisture and protect against further irritation
• PreserVision® and Ocuvite® combined are the #1 brand
and the #1 driver of growth in eye vitamins category10
PreserVision® has the only
ARED2 formulation recommended
by the National Eye Institute to
help reduce the risk of
progression by 25% in people
with moderate-to-advanced AMD9
6. Multi-sponsor Surveys, Inc., The 2017 Gallup Study of Dry Eye Sufferers. 7. Lemp, M. A., Crews, L. A., Bron, A. J., Foulks, G. N., & Sullivan, B. D. (2012). Distribution of Aqueous-Deficient and Evaporative Dry Eye in a Clinic-Based Patient Cohort. Cornea, 31(5), 472-478. doi:10.1097/ico.0b013e318225415a. 8. Prevalence of Blindness Data. https://nei.nih.gov/eyedata/pbd_tables. Accessed September 11, 2017 IRI Panel data L52 week ending 12/2/18. 9. Age-Related Eye Disease Study Research Group. Arch Ophthalmol. 2001;119(10):1417-1436. 10. IRI Total US Mulo Latest 52 Weeks Ending 09-30-18 (dollar sales).
Global Surgical: Innovation and Platform Expansion
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Developing a
Premium Portfolio and
Expanding the Market
New in 2018 • enVista® toric MX60T
intraocular lens (IOL)
• Crystalsert® 2.6 injector (CI-26)
• 25- and 27-gauge Bi-Blade®
dual port vitrectomy cutters for
the Stellaris Elite™ platform
Innovative Technologies • Stellaris Elite™ platform
• Vitesse®
Software Innovation
Helping eye surgeons
increase efficiency, cut costs
and improve workflow
• New eyeTELLIGENCE™
applications, which run on the
IBM Cloud, to help eye
surgeons and surgical facilities
optimize practice efficiency
when using the company’s
Stellaris Elite™ platform
Expanding Our Platform
Continued R&D investment
• Two clinical trials underway
investigating new surgical
technologies; a novel
ophthalmic viscosurgical device
formulation as well as an
investigational trifocal IOL, the
enVista® MX60EF IOL
Market
Opportunity
• ~25M cataract surgeries were done globally in 20181
• Globally, an estimated 330M people have cataracts and do not use surgical
intervention2
• Number of people blind from cataracts in the world is estimated to be increasing
by ~1M per year3
1. Market scope. 2. Market scope estimate based on WHO 2017 Global Data on Vision Impairment and a 2005 British Journal of Ophthalmology article. 3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705965/.
Brings Eye Care Professionals A Dual Mechanism of Action
• VYZULTA® is the first and only FDA-approved nitric oxide–releasing agent that
targets both the uveoscleral and trabecular meshwork pathways to lower
intraocular pressure in patients with glaucoma or ocular hypertension
• Nitric oxide increases trabecular meshwork outflow by inhibiting 2 key causes of
trabecular meshwork cellular contraction: Rho Kinase and Calcium Signaling
Has Proven Efficacy
• In the Apollo and Lunar Studies, mean IOP reduction of 7.5 to 9.1mmHg from
baseline, in Phase 3 trials vs timolol 0.5% were achieved3,4
• In the Voyager Study, 34.6% reduction of IOP from baseline was achieved with
VYZULTA® patients compared to 29.8% with Xalatan (latanoprost) 0.005%5
• In a post hoc analysis, 42% of patients achieved a reduction of at least 2mmHg
more with VYZULTA® than the mean diurnal IOP reduction for Xalatan6
Has A Demonstrated Safety and Tolerability Profile
• VYZULTA® had a less than 1% dropout rate in Phase 3 trials
• Hyperemia was reported in less than 6% of patients
Latanoprost, 71%
Lumigan, 15%
Travantan Z, 13%
All Other, 1% Xalatan, 0%
Global Ophthalmology Rx:
VYZULTA® Market Opportunity
Surgical, Ophtho and International
1. IQVIA TRx data (Nov 2018). 2. IMS Smart TRx 12 months total TRx through 11/2017. 3. Weinreb RN, Scassellati Sforzolini B, Vittitow J, Liebmann J. Latanoprostene bunod 0.024% versus Timolol maleate 0.5% in
subjects with open-angle glaucoma or ocular hypertension: the APOLLO study. Ophthalmology. 2016;123(5):965-973. 4. Medeiros FA, Martin KR, Peace J, et al. Comparison of latanoprostene bunod 0.024% and timolol maleate 0.5% in open-
angle glaucoma or ocular hypertension: the LUNAR study. Am J Ophthalmol. 2016;168:250-259.
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U.S. Prostaglandin Market (TRx Data)2
Prostaglandins represent 80% of the
U.S. glaucoma market1
Why VYZULTA®?
Now Available: Medicare Part D 30% coverage and more to come
Commercial Coverage: 80%
Including ESI and CVS
5. Weinreb RN, Ong T, Scassellati Sforzolini B, et al. A randomised, controlled comparison of latanoprostene bunod and latanoprost 0.005% in the treatment of ocular hypertension and open angle glaucoma: the VOYAGER study. Br J Ophthalmol. 2015;99:738-745. 6. Weinreb RN, Ong T, Scassellati SB, et al. A randomised, controlled comparison of latanoprostene bunod and latanoprost 0.005% in the treatment of ocular hypertension and open angle glaucoma: the VOYAGER study. Br J Ophthalmol. June 2015;99(6):738-745.
Now Approved
in Canada
• Strong Durable Growth: Delivered 16% organic revenue
growth1,2 during first three quarters of 2018 compared to first
three quarters of 2017, driven by continued strong fundamental
growth in XIFAXAN® and RELISTOR®, despite UCERIS® LOE
4 new collaborations and 3 new products, including
• Resolved XIFAXAN® IP litigation: Preserved market
exclusivity until 20283 with no financial payments made by
Bausch Health
• Resolved legacy Salix SEC investigation with no monetary
penalty4
• Resolved outstanding arbitration with Alfasigma S.p.A.
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1. See Slide 3 for further non-GAAP information. See our 3Q18 earnings presentation for GAAP reconciliation and other non-GAAP information at https://ir.bauschhealth.com/~/media/Files/V/Valeant-IR/reports-and-presentations/3q18-bausch-health-earnings-presentation.pdf.
2. Organic growth or change, a non-GAAP metric, is defined as a change on a year-over-year basis in revenues and/or operating results on a constant currency basis (if applicable) excluding the impact of divestitures and discontinuations.
3. Actavis will be able to begin marketing the medicine earlier if another generic rifaximin product is granted approval and starts selling or distributing such generic rifaximin product before Jan. 1, 2028.
• Expected continued growth across the segment’s promoted
brands including, +$1B product XIFAXAN® and RELISTOR®
• 4 late stage R&D programs ongoing and/or planned for 2019
Bolt-on Opportunity: “Stalking Horse” Agreement
Pending acquisition of certain assets of Synergy Pharmaceuticals,
which is expected to close in 1Q195, includes:
• TRULANCE® for adults with chronic idiopathic constipation and
irritable bowel syndrome with constipation (IBS-C)
• Pipeline: Investigational compound dolcanatide, which has
demonstrated proof-of-concept in treating patients with opioid-
induced constipation and ulcerative colitis
Coming in 2019 2018 Highlights
Formulation Indication Clinical Status Development
Start Date (Ready)
Rifaximin SSD Acute OHE Phase 2 FH 2018
Rifaximin EIR Post Operative Crohn’s Disease Phase 3 FH 20196
Xifaxan 550 mg Prevention of Complications of
Decompensated Cirrhosis Phase 2 FH 20196
Xifaxan 550 mg SIBO Phase 2 FH 20196
XIFAXAN® RELISTOR® APRISO®
+26%
+62%
+9%
Revenue growth YTD as of 9.30.18 vs. YTD as of 9.30.17
4. Subject to approval by the U.S. District Court for the Southern District of New York. 5. Subject to other interested parties having an opportunity to submit competing bids, bankruptcy court approval and other customary closing conditions. 6. Anticipated start date. 7. Co-promotion arrangement with third party.
Salix: Leading Our Pivot to Offense
7 7
24%
45%
15%
25%
35%
45%
55%
Oct-16 Feb-17 Jun-17 Oct-17 Feb-18 Jun-18 Oct-18
%S
ha
re
P=0.03
7% 2%
66%
25%
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IBS-D: Large Untapped Market Opportunity
1. IQVIA Rx Monthly (Xponent). 2. IQVIA SMART Factored Rx weekly (Q4 2018). 3. Response defined as simultaneously meeting weekly response criteria for abdominal pain (≥30%, ≥40%, or ≥50% improvement from baseline in the weekly average abdominal pain score) and bloating (≥1-point
decrease from baseline in weekly average bloating score) during ≥2 weeks of the first 4 weeks post-treatment. 4. Lacy, B., et al. Rifaximin for Improving Abdominal Pain and Bloating Symptoms in Patients With Irritable Bowel Syndrome With Diarrhea Using Modified Definitions of Pain Response. Poster Presented at the
American College of Gastroenterology 2018 Scientific Meeting; October 5-10, 2018; Philadelphia, PA.
Feb. 2017 Primary Care team added
2017-2018 Results from Primary Care expansion
2019 & Beyond Focus on remaining large untapped market
Added Primary
Care Team
XIFAXAN® IBS-D NRx Branded Share in Primary Care1
>90% of the market
remains untapped
IBS-D Market Opportunity (in TRx Volume)2
XIFAXAN®
Competitor
Antispasmodic
Antidiarrheals
Two-week courses of rifaximin 500 mg TID
provided consistent (open-label vs. double-blind),
significant and durable improvement in abdominal
pain and bloating symptoms vs. placebo using
modified definitions of IBS-D response
47.7
43.6
37.2
40.5
35.4
28.4
31.5
27.3
23.4
0
10
20
30
40
50
60
≥30% abdominal pain and ≥1-point bloating response
during ≥2 weeks of first 4 weeks post-treatment
≥40% abdominal pain and ≥1-point bloating response
during ≥2 weeks of first 4 weeks post-treatment
≥50% abdominal pain and ≥1-point bloating response
during ≥2 weeks of first 4 weeks post-treatment
Responders
(%
)
Open-label rifaximin (n=2438)
Double-blind rifaximin (n=328)
Double-blind placebo (n=308)
P=0.02
P=0.17
n=
1163
n=
133
n=
97
n=
1062
n=
116
n=
84
n=
906
n=
93
n=
72
Abdominal Pain and Bloating Response3,4
0
20
40
60
80
100
Phototherapy Topicalmedications
Oralmedications
Biologicmedications
Other Nothing
13
Ortho Dermatologics: 2019 Catalysts
New Products, New Market Access Model
1. Rachakonda TD et al. J Am Acad Dermatol. 2014 Mar. Psoriasis prevalence among adults in the United States https://www.ncbi.nlm.nih.gov/pubmed/24388724.
2. Cowen. Therapeutic Outlook Dermatology. March 2016. 3. IMS Claims Data. April 2015- March 2016, IQVIA. Data on file. 4. National Psoriasis Foundation 2018 Survey, N=314. 5. LiquidHub.
Psoriasis Focus
• Large Market Opportunity: 7.5M psoriasis sufferers in the
U.S. with 150,000 to 260,000 new cases of psoriasis
diagnosed each year1,2,3
• Population Not Satisfied with Current Therapies
• >90% of patients are open to new treatments4
• Only 10% of patients are extremely or very satisfied
with current treatments4
• >60% of patients have been on 5 or more products for
the treatment of plaque psoriasis4
• Topical Therapy Preferred Method: >85% of patients on
therapy use topical medication4
% of Patients on Therapy4
3 New Products to Serve the Unmet Needs of Patients
• Expected to be the first and only topical lotion that contains a unique
combination of halobetasol propionate and tazarotene in one formulation
for the treatment of plaque psoriasis in adult patients, allowing for a
potentially expanded duration of use
• For the patient with more moderate-to-severe disease, chronic or long-
lasting episodes and thicker, stubborn plaques
• New potent topical steroid treatment for plaque psoriasis; safety has
been established in clinical trials with dosing for up to 8 weeks with no
increase in epidermal atrophy
• For the patient with more mild-to-moderate disease, sporadic flares and
symptomatic irritation
– PDUFA Feb. 15, 2019
Launch expected 1Q197
– Launched Nov. 2018
– Expanded Launch Jan. 2018
• First and only IL-17 Receptor A Blocker resonates with physicians who
remain impressed with its fast response and high percentage of patients
reaching complete clearance
• ~80% of patients started on SILIQ™ have stayed on therapy5
6
Solta: Delivered 17% organic revenue growth8,9 during
first three quarters of 2018 compared to first three
quarters of 2017
6. Provisional name. 7.Subject to FDA approval. 8. See Slide 3 for further non-GAAP information. See also our 3Q18 earnings presentation at https://ir.bauschhealth.com/~/media/Files/V/Valeant-IR/reports-and-presentations/3q18-bausch-health-earnings-presentation.pdf for GAAP reconciliation and other non-GAAP information. 9. Organic growth, a non-GAAP metric, is defined as an increase on a year-over-year basis in revenues and/or operating results on a constant currency basis (if applicable) excluding the impact of divestitures and discontinuations.
14
Ortho Dermatologics:
Extensive Pipeline to Fuel Growth
1. Expected. 2. Provisional name. 3. Subject to FDA approval. 4. Proof of concept.
Psoriasis
BRYHALI™ (Launched Nov. 2018): New potent to super potent topical corticosteroid treatment for plaque psoriasis;
safety has been established in clinical trials with dosing for up to 8 weeks with no increase in epidermal atrophy; for the
patient with more mild-to-moderate disease, sporadic flares and symptomatic irritation
DUOBRII™2 (PDUFA Feb. 15, 2019; launch expected 1Q193): Expected to be the first and only topical lotion that
contains a unique combination of halobetasol propionate and tazarotene in one formulation for the treatment of plaque
psoriasis in adult patients, allowing for a potentially expanded duration of use; for the patient with more moderate-to-
severe disease, chronic or long-lasting episodes and thicker, stubborn plaques
IDP-131 (KP-470) (POC4 planned for 2019): New chemical entity with novel mechanism of action for psoriasis
ALTRENO™ (Launched Oct. 2018): First and only .05% tretinoin lotion; is a cosmetically elegant formulation that the
patient targets – adult women – want but are not able to get from their dermatologist because of a challenging payer
environment; cash-only option allows patients to get the product at a predictable price point and bypass the hassle of
insurance allowing the treatment decision to be back in the hands of the dermatologist and patient
IDP-120 (Submit 20201): First fixed combination tretinoin/benzoyl peroxide in novel dual chamber pump; previously
two efficacious products were not able to be delivered together because they degrade each other
IDP-123 (Submit 20191): First tazarotene lotion, unique concentration at less than half of approved tazarotene
products for acne
IDP-126 (Submit 20211): First topical triple combination product for acne
Also, OTC acne product opportunity Acne
IDP-124 (Submit 20201): First pimecrolimus lotion, target moderate to severe atopic dermatitis
IDP-133 (Submit 20211): Expand halobetasol propionate lotion beyond psoriasis for all steroid responsive dermatoses
Atopic
Dermatitis
Solta Thermage FLX®: Launched in U.S. and Hong Kong (2017), Thailand, South Korea and Japan (3Q18) and China,
Vietnam and Australia (4Q18); planned launches in Taiwan, Canada, South East Asia and EMEA (2019)
15
Plan to separate into two access models with the goal to deliver improved,
predictable and sustainable patient fulfillment options for our skin care products
Reimbursed Medical Dermatology
Innovative prescription Rx products featuring
strong value propositions for patients and payers
promoted and distributed in the traditional
specialty pharma model
Cash Pay Dermatology
Leading legacy brands prescribed by physicians,
desired by patients and purchased via cash-pay
channels
&
We believe that the emerging Cash Pay Dermatology business will enable us to
preserve and capture, in a durable way, the brand equity associated with Solta
and our legacy dermatology products as well as several pipeline assets facing
challenging patient access environments.
>5 leading legacy brands
expect to be added in 2019
A Transformational Business Model
>5 investigational products
expect to be added
1,2
1. Investigational product subject to FDA approval. 2. Provisional name.
Over $1B
Significant Seven New Product Launches Expected to Drive Long-Term Growth
Launched Sept. 2016
RELISTOR® (methylnatrexone bromide)
Launched Dec. 2017
VYZULTA® (latanoprostene bunod
ophthalmic solution) PDUFA Feb. 15, 2019
Launched July 2017 Launched May 2018
First Launch Sept. 20183; Plans for global rollout
<$100M
in annualized revenues
as of end of 2017
Expected annualized peak total
revenues by the end of 2022
(SiHy Daily)
1. Investigational product subject to FDA approval. 2. Provisional name. 3. In Japan. 4. Expected.
1,2
Launched Nov. 2018
2017
~$75M
2018
>$150M4
2019
~$300M4
2020
2021
2022
16
2018 Achievements and 2019 Catalysts
2019 2018
Bausch + Lomb/International VYZULTA® Launched
Stellaris Elite™ Launched
LUMIFY® Launched
AQUALOX™ (SiHy Daily) Launched in Japan
Crystalsert® 2.6 Injector Launched
Bausch + Lomb ULTRA® Multi-Focal for Astigmatism
Approved
Consumer E-commerce Growth (Amazon and Alibaba)
Salix PLENVU® Approved and Launched
XIFAXAN® Next Generation Clinical Trial
Ortho Dermatologics Psoriasis / SILIQ™ sales force expansion
ALTRENO™ Approved and Launched
BRYHALI™ Approved and Launched
DUOBRII™1 Resubmission with PDUFA date Feb. 15, 2019
Corporate / Other Resolved Allergan securities litigation
Additional debt repayments to a total of $1.07B in 2018
OraPharma co-promotion of SPRIX®
Bausch + Lomb/International Planned launch of Bausch + Lomb ULTRA® Multi-Focal for
Astigmatism
Continued planned expansion for daily disposable parameter
offerings
Specialty Vision Products (anticipated): Zen Multifocal and
Tangible Science Hydra-PEG® coating
Planned improvement for flagship PreserVision® AREDS2
offering: Smaller size softgel product
Ocuvite® eye performance planned line extension
Loteprednol Etabonate Ophthalmic Gel, 0.38% (Ocular
Inflammation) – PDUFA date Feb. 25, 2019
Consumer E-commerce growth expected
Salix 4 late-stage R&D programs in progress
“Bolt-on” opportunities: pending acquisition of certain assets
from Synergy Pharmaceuticals3
Ortho Dermatologics ALTRENO™ Planned Full-year Launch
BRYHALI™ Planned Full-year Launch
DUOBRII™1 PDUFA date Feb. 15, 2019; Launch expected in
1Q192
Thermage FLX® launches planned in Taiwan, Canada, South
East Asia and EMEA
IDP-123 anticipated submission
New access model to be implemented
17 1. Provisional name. 2. Subject to FDA approval. 3. Subject to other interested parties having an opportunity to submit competing bids, bankruptcy court approval and other customary closing conditions..
18
Bausch Health expects 3yr CAGR2 of revenue growth of 4% - 6% and Adjusted
EBITDA (non-GAAP)1 growth of 5% - 8% during 2018-2021
• Expect reported revenue for total company to grow in 2019 vs. 2018,
based on today’s FX rate
• Expected cash generated from operations of >$1B to be used to reduce
debt and/or for “bolt-on” acquisitions
• R&D investment expected to grow by ~10% in 2019 vs. 2018
• Revenue generated from the Significant Seven expected to
approximately double in 2019 vs. 2018
• Continued improvement in operational efficiency (i.e. Project CORE)
expected to deliver >$75M in 2019
2019: Pivot to Offense
Year of Growth for Bausch Health
1. See Slide 3 for further non-GAAP information. See our 3Q18 earnings presentation for GAAP reconciliation and other non-GAAP information at https://ir.bauschhealth.com/~/media/Files/V/Valeant-IR/reports-and-presentations/3q18-bausch-health-earnings-presentation.pdf.
2. Compound annual growth rate.
19
Appendix
20
Reconciliation of Reported Growth to Organic Growth ($M)
(Year-to-Date)1
Revenue
as
Reported
Changes
in
Exchange
Rates (a)
Organic
Revenue
(Non-
GAAP) (b)
Revenue
as
Reported
Divested
Revenues
Organic
Revenue
(Non-
GAAP) (b)
Amount Pct.
B+L / International and Salix 4,782 (59) 4,723 4,732 (290) 4,442 281 6%
Change in
2018 2017 Organic Revenue
(a) The impact for changes in foreign currency exchange rates is determined as the difference in the current period reported revenues at their current period currency exchange rates and the current period reported revenues revalued using the monthly average currency exchange rates during the
comparable prior period.
(b) To supplement the financial measures prepared in accordance with U.S. generally accepted accounting principles (GAAP), the Company uses certain non-GAAP financial measures. For additional information about the Company’s use of such non-GAAP financial measures, refer to Slide 3. Organic
revenue and/or operating results (non-GAAP) for the current year are calculated as revenue and/or operating results as reported adjusted for the impact for changes in exchange rates. Organic revenue and/or operating results (non-GAAP) for the prior year are calculated as revenue and/or operating results
as reported less revenues and/or operating results attributable to divestitures and discontinuances during the twelve months prior to the day of divestiture or discontinuance, as there are no revenues and/or operating results from those businesses and assets included in the comparable current period.
Organic revenue and/or operating results is also adjusted for acquisitions.
1. YTD at September 30, 2018 vs. YTD at September 30, 2017. 2. YTD as of September 30.
2 2