2017 ADVANCED BIOMANUFACTURING SPONSORS - Conferences @ WID – Wisconsin … · 2017-08-18 ·...
Transcript of 2017 ADVANCED BIOMANUFACTURING SPONSORS - Conferences @ WID – Wisconsin … · 2017-08-18 ·...
2017ADVANCEDBIO
MAN
UFACTU
RINGSPO
NSO
RS
ThankyouforourgrantsupportfromtheNationalScienceFoundation.
Gold
Silver
Bronze
ThankYouforourSponsors’GenerousSupport
MadisonIBMES-ABioM20171
TABLEOFCO
NTEN
TS
Welcome………………………………….………………………………………. 2
ScientificCommitteeMembers………………………………………… 3
KeynoteSpeakers
StatusofAdvancedBiomanufacturingSession…………….. 5
EmergingConceptsSession…………………………………………. 7
FutureofAdvancedBiomanufacturingSessionI………….. 8
FutureofAdvancedBiomanufacturingSessionII............ 9
CurrentAdvancesinBiomanufacturingSession……………. 9
FutureAdvancesinBiomanufacturingSession……………… 11
2017ABioMAwardRecipients………………………………………….. 12
AbstractReviewers………………………………………………………….. 13
GeneralInformation………………………………………………………… 13
PosterSession…………………………………………………………………. 15
ProgramataGlance……………………………………………………….. 19
MadisonIBMES-ABioM20172
LETTERFROMTHECHAIRS
RandolphS.Ashton,PhDAnnualMeetingCo-Chair
AssistantProfessorBiomedicalEngineering
WisconsinInstituteforDiscoveryUniversityofWisconsin-Madison
WilliamMurphy,PhDAnnualMeetingCo-ChairHarveyD.SpanglerProfessor
BiomedicalEngineering
WisconsinInstituteforMedicalResearchUniversityofWisconsin-Madison
elcometotheinauguralmeetingoftheBiomedicalEngineeringSociety’sAdvancedBiomanufacturingSpecialInterestGroup(ABioM-SIG).Youractiveparticipationinthe
conferenceishighlyencouragedasweseektodefinethecurrentstateandfuturegoalsoftheABioMfield.Consistentwiththeconference’stheme,weaimtoidentifyopportunitiesandchallengesassociatedwithtranslatingthepharmaceuticalindustry’ssuccessfulclinicalmanufactureofsmallmoleculeandbiologictherapeuticstotheadvancedbiomanufactureofgenetherapiesandhumancell,tissueandtissue-relatedtechnologies.Thisincludesconsiderationofrequisitelogistical/supportiveinfrastructureandworkforcedevelopment.Tofacilitatethisprocess,wehaveassembledheadsofbiomanufacturingcorporations,leadersofrelevantindustry/academicinitiatives,manufacturesofclinicalcellandtissuetherapies,innovatorsofnext-generationregenerativeapproaches,anddirectorsofrelatedworkforcetraininginitiativestoparticipateinahighlyinteractiveprogram.WehopethatthepresentedinformationanddiscussionsprovideaconciseoverviewoftheABioMfield,forecastnoveladvancements,andevokeproductivecollaborationsandpartnerships.ThisconferencewouldnothavebeenpossiblewithouttheassistanceofmanystakeholdersintheABioMfield,andweofferthemoursincerestgratitude.TheWisconsinInstituteforDiscoveryservingbothasourmeetinghostandasponsorisatransdisciplinaryresearchinstitutewithABioMasoneofitscoreresearchfoci.TheconferenceisalsosponsoredbytheNationalScienceFoundation(#1743396),WiCell®,WorcesterPolytechnicInstitute,WaismanBiomanufacturing,theGraingerInstituteforEngineeringandtheBiomedicalEngineeringDepartmentintheCollegeofEngineeringatUW-Madison,andW.NuhsbaumIncorporated.DedicatedfacultymembersofboththeABioM-SIGandUW-Madison’sStemCellandRegenerativeMedicineCenterprovidedtheirtimetoassistwithabstractreviewsandawardselections.Also,specialthanksareduetomembersoftheorganizingscientificcommitteefortheirserviceanddedicationtothisendeavor.Mayyouhaveanenjoyableandproductivemeeting!
W
MadisonIBMES-ABioM20173
SCIENTIFICCO
MMITTEEM
EMBERS
KaimingYe,PhDAnnualMeetingProgramCo-Chair
ProfessorandChairBiomedicalEngineering
SUNYBinghamton
GlennR.Gaudette,PhDAnnualMeetingProgramCo-Chair
ProfessorBiomedicalEngineering
WorcesterPolytechnicInstitute
RolandKaunas,PhD
ScientificCommitteeMemberAssociateProfessor
BiomedicalEngineering
TexasA&MUniversity
ElizabethLipke,PhD
ScientificCommitteeMemberMaryandJohnH.SandersAssociate
ProfessorChemicalEngineeringAubrunUniversity
MadisonIBMES-ABioM20174
KEYNOTESPEAKERS
PaulGoodwinistheScienceDirectorforGEHealthcare’sLifeSciencesbusiness,locatedintheSeattle,WAarea.PaulreceivedhisBachelor’sdegreeinBiologyfromtheUniversityofCalifornia,SanDiegoandcontinuedhiseducationintheDepartmentofPhysiologyandBiophysicsattheUniversityofWashington,Seattle,WAwhereheobtainedaMaster’sdegree.HethenbeganworkasaResearchTechnicianintheDepartmentofPathologyattheUniversityofWashingtoninthelaboratoryofDr.RussellRoss.Itwasherethathewasintroducedtotheuseofdigitalimageprocessingandimageanalysiswithlightandelectronmicroscopy.PaulwasrecruitedbytheFredHutchinsonCancerResearchCentertocreateandmanagetheImageAnalysisCoreFacilitywherehedevelopedanumberofnewimagingtechniques.
Aftertenyears,hewasrecruitedtoAppliedPrecision,Inc.inIssaquah,WAwherehehasservedvariousrolesinadvancedapplicationdevelopment,productmanagement,andR&D.AsScienceDirector,heworkswithteamsacrosstheLifeSciencesbusinesstoidentifyandsolvetechnicalchallengesthataffectourcustomersandourbusiness.Healsosupportsinnovationandprovidesbothvisionandstrategicplanningfortheorganization.PaulisanAffiliateTeachingAssociateintheDepartmentofComparativeMedicineattheUniversityofWashington,Seattle,WA.Heisanexpertinthree-dimensionaloptics,deconvolution,super-resolutionmicroscopy,andinstrumentdevelopment.HelecturesfrequentlyandservesasfacultyformicroscopycoursesattheMarineBiologicalLaboratory,WoodsHole,MAincludingtheImmunohistochemistryandMicroscopycoursesupportedbytheHistochemicalSociety.HehasbeenaCounciloroftheSocietysince2013andiscurrentlythePresident-ElectoftheHistochemicalSociety.GeorgeJ.ChrististheProfessorofBMEandOrthopaedicSurgery,MaryMuilenbrrgStampProfessorofOrthopaedicSurgery,andDirectorofBasicScience&TranslationalResearchforOrthopaedicSurgery,UninversityofVirginia.HeistheCo-DirectoroftheCenterforAdvancedBiomanufacturingattheUniversity
StatusofAdvancedBiomanufacturingSessionFriday–8:40AM
PaulGoodwin,PhD
ScienceDirector,LifeScienceDivisionGEHealthcare
Friday,August18,20178:40–9:15AM
GeorgeJ.Christ,PhDMaryMuilenbrrgStampProfessor,
BiomedicalEngineering&OrthopaedicSurgeryUniversityofVirginia
Friday,August18,20179:15–9:50AM
MadisonIBMES-ABioM20175
KEYNOTESPEAKERS
ofVirginia.Dr.ChristisamemberofAIMBE,thePastChairmanoftheDivisionofSystemsandIntegrativePharmacologyoftheAmericanSocietyofPharmacologyandExperimentalTherapeutics(ASPET),andPastPresidentoftheNorthCarolinaTissueEngineeringandRegenerativeMedicine(NCTERM)group.HeisontheEditorialBoardoffivejournalsandisanad-hocreviewerfor2dozenothers.Dr.Christhasauthored222scientificpublicationsandisco-editorofabookonintegrativesmoothmusclephysiologyandanotheronregenerativepharmacology.Dr.Christhasservedonbothnationalandinternationalcommitteesrelatedtohisexpertiseinmusclephysiology,andonNIHstudysectionsintheNIDDK,NICHD,NCRRandNHLBI.HehaschairedworkinggroupsforboththeNIHandtheWorldHealthOrganization.Dr.Christisaco-inventoronmorethan26patents(nationalandinternational)thatareeitherissuedorpending,relatedtogenetherapyforthetreatmentofhumansmoothmuscledisordersandtissueengineeringtechnologies.Dr.ChristhasalsobeenthedrivingscientificforcebehindthepreclinicalstudiesandINDapprovalssupportingthreePhaseIclinicaltrialsforgenetherapyforbenignhumansmoothmuscledisorders.Thistechnologyhasbeenevaluatedin55patientsintheUSand21overseas.Heisalsospearheadingthemulti-institutionaldevelopmentofatissueengineeredmusclerepair(TEMR)technologyplatformforthetreatmentofWoundedWarriors.AnINDsubmissionfora5patientfirst-in-manpilotstudyisanticipatedin2017tofurtherdevelopthistechnologyplatformfortreatmentofcleftlip.ThatstudyisfundedbyDODandwillbeconductedatUT-Houston.Another5patientpilotstudyhasalsobeenfundedbyDODtoevaluateaproprietaryhydrogelforthetreatmentoflowerextremityvolumetricmusclelossinjuriestothetibialisanteriormuscleatUVA.AnIDEapplicationforthatindicationisalsoanticipatedin2017.Dr.Christhasbeenextensivelyinvolvedinbasicandtranslationalstudiesofregenerativemedicinedirectedtowardvesseltissueengineeringandbladderregeneration,andmostrecently,regenerativepharmacology.
MarkJ.TomishimaistheHeadoftheSKIStemCellResearchFacility,partoftheCenterforStemCellBiologyandtheDevelopmentalBiologyProgramatSloanKetteringInstituteinNewYorkCity.Dr.TomishimaearnedhisPh.D.atPrincetonUniversitywherehestudiedthemovementofalpha-herpesvirusesthroughneurons.Atthetime,thisworkrequiredprimaryneuronculturethatlimitedthroughput.AfterearninghisPh.D.,heperformedpostdoctoralworkwithLorenzStuderatSloanKetteringwherehelearnedtoconvertpluripotentstemcellstounlimitedamountsofneurons,bypassingtheneedfortheprimaryculture.IntheStuderLab,Dr.Tomishimapioneeredtheuseofbacterialartificialchromosomesthatwereusedtopurifypopulationsofneuralcells.Suchpurifiedpopulationsareusefulinunderstandingthetranscriptomeofdifferentneuralcellpopulations,andallowedfortransplantationofdifferentstagesofESC-derivedneuralcellsintoanimalmodelsof
Parkinson’sdisease.Hewasalsopartofaninternationalteamthatusednuclearcloningtechnologytocreateapluripotent,autologousmodelofParkinson’scelltherapy.Forthepastdecade,Dr.TomishimahasruntheSKIStemCellResearch
MarkJ.Tomishima,PhDHeadofSloanKetteringInstitute
StemCellResearchFacilitySloanKetteringInstitute
Friday,August18,20179:50–10:25AM
MadisonIBMES-ABioM20176
KEYNOTESPEAKERS
Facility,ahumanpluripotentstemcellsharedfacilitythatprovidesanumberofservicestothestemcellcommunity.Onefocusofhisgroupwastoperformtheprocess,assayandSOP/BRdevelopmentaroundMSKDA01,ahumanembryonicstemcell-derivedmidbrainfloorplateanddopamineneuronproductintendedtotreatParkinson’sdiseasepatients.Dr.TomishimaandhisgroupmanufacturedMSKDA01inacGMPcleanroomandtheproductiscurrentlyundergoingthefinalIND-enablingstudies.TheLorenzStuder-ledconsortiumhopestofiletheINDapplicationwiththeFDAinthesummerof2018.
DeepakVashishthistheDirectoroftheRensselaerPolytechnicInstituteCenterforBiotechnology&InterdisciplinaryStudies(CBIS),conductingbreakthroughresearchonbonesandworkingtoredefinetheroleofatoptierresearchuniversity:onethatisengagedinpublicandprivatepartnerships,involvedininterdisciplinaryresearch,andprovidingqualityeducation,alltodriveentrepreneurial,sustainable,sociallyresponsiblescientificdiscoveryandtechnologicalinnovation.ThroughhisworkasaUniversityCenterDirectorsince2013,previouslyasaSchoolofEngineeringDepartmenthead(2009-2013),andinprofessionalsocietieshehassuccessfullydevelopedpartnerships,programsandplatforms,todrivetranslationalscientificresearchacrossdisciplines,sectors,andgeographicboundaries.HeearnedhisB.EngwithhonorsfromMalaviyaNationalInstituteofTechnology(India),MSfrom
WestVirginiaUniversity(USA)andPhDfromtheUniversityofLondon(UK).Hethenconductedpost-doctoralresearchattheBoneandJointCenter,DepartmentofOrthopaedicSurgery,HenryFordHospitalbeforejoiningRensselaerasanAssistantProfessorinBiomedicalEngineeringin1999.Hisresearchinterestsareintheareaofbiomolecularscienceandengineeringofextracellularmatrixwithparticularemphasisonbonetissueengineeringanddiagnosisandtreatmentofosteoporosis.Workingincollaborationwithothers,hisresearchgrouphasidentifiednewstructuralrolesforboneproteinsanddevelopednewbiomimickry-basedstrategiesfortissueengineeringscaffolds.Heisbringinghisbreakthroughresearchtomarket,co-foundingacompany(Orthograftplc),toproducetheacellularbiomimeticgraftsforbonerepair.ProfessorVashishthandhisresearchgrouphavepublishedmorethan200peer-reviewedjournalpublicationsandconferenceproceedingsintopjournalsincludingPNAS,MolecularandCellularProteomics,Langmuirandothers.HeisfellowoftheAIMBEandservesasAcademicEditorforPloSOneandeditorialboardmemberforBoneandtheJournaloftheMechanicalBehaviorofBiomedicalMaterials.HeisamemberoftheBiomedicalEngineering
EmergingConceptsSessionFriday–10:50AM
DeepakVashishth,PhDProfessor,BiomedicalEngineeringDirector,CenterforBiotechnology
andInterdisciplinaryStudiesRensselaerPolytechnicInstitute
Friday,August18,201710:50–11:25AM
MadisonIBMES-ABioM20177
KEYNOTESPEAKERS
Society,AmericanSocietyofBoneandMineralResearch,AmericanAssociaionforAdvancementofScience,andtheOrthopaedicResearchSociety.
Dr.Krishnendu(Krish)RoyreceivedhisundergraduatedegreefromtheIndianInstituteofTechnology(India)followedbyhisMSfromBostonUniversityandhisPhDinBiomedicalEngineeringfromJohnsHopkinsUniversity.FollowinghisPhD,hejoinedZycosInc.,astart-upbiotechnologycompanywhereheservedfirstasaScientistandthenasaSeniorScientistintheDrugDeliveryResearchgroup.Dr.RoylefthisindustrialpositiontojoinTheUniversityofTexasatAustinin2002,wherehewasmostrecentlyProfessorandFellowoftheCockrellChairinEngineeringExcellence.HeleftUT-AustininJulyof2013tomovetoGeorgiaTech.whereheiscurrentlytheRobertA.MiltonChair.AtGeorgiaTech,healsoservesastheDirectorofthenewlyestablishedMarcusCenterforCell-TherapyCharacterizationandManufacturingaswellastheDirectoroftheCenterforImmunoEngineering,aconsortiumof30+facultyfocusedonusingengineeringtoolsandmethodologiestounderstandandmodulatetheimmunesysteminhealthanddisease.HeisalsotheTechnicalLeadoftheNIST/AMTechNationalCell
ManufacturingConsortium(NCMC),anationalpublic-privatepartnership,focusedonaddressingthechallengesandsolutionsforlargescalemanufacturingoftherapeuticcells.Dr.Roy’sresearchinterestsareintheareasofscalablecellmanufacturing,Immuno-engineering,stem-cellengineeringandcontrolleddrugandvaccinedeliverytechnologies,withparticularfocusinbiomedicalmaterials.Inrecognitionofhisseminalcontributiontothesefields,Dr.RoyhasbeenelectedFellowoftheAmericanInstituteforMedicalandBiologicalEngineering(AIMBE)andFellowoftheBiomedicalEngineeringSociety(BMES).Inaddition,Dr.RoyhasreceivednumerousawardsandhonorsincludingYoungInvestigatorAwardsfromboththeControlledReleaseSociety(CRS)andTheSocietyforBiomaterials(SFB),theYoungScientistAwardfromHSEMB,NSFCAREERaward,GlobalIndusTechnovatorAwardfromMIT,theCRSCygnusAwardetc.HeisalsotherecipientofBestTeacherAwardgivenbytheBiomedicalEngineeringStudentsatTheUniversityofTexasandthebestadvisorawardgivenbybioengineeringstudentsatGeorgiaTech.HeservesasamemberoftheEditorialBoardsoftheJournalofControlledReleaseandtheEuropeanJournalofPharmaceuticsandBiopharmaceutics.HealsoservesasamemberoftheForumonRegenerativeMedicineoftheNationalAcademiesandasco-ChairoftheWorkingGroupoftheStandardsCoordinatingBody(SCB)forCellandRegenerativeTherapies.
FutureofAdvancedBiomanufacturingSessionIFriday–1:25PM
KrishnenduRoy,PhD
RobertA.MiltonChairandProfessor,BiomedicalEngineering
Director,MarcusCenterforCell-TherapyCharacterizationand
Manufacturing(MC3M)GeorgiaInstituteofTechnology
Friday,August18,20171:25–2:00PM
MadisonIBMES-ABioM20178
KEYNOTESPEAKERS
RichardMcFarland,PhD,MDistheChiefRegulatoryOfficerofARMI/BioFabUSA,aninstitutewithintheManufacturingUSAnetwork.Theinstitute’sgoalsincludecreatinganindustrialcommonswiththeaimstocoalescethefieldandprovidearoutefornascentproductconceptsinTE/RMtoreachthemarketplace.PriortoARMI,Dr.McFarlandwasAssociateDirectorforPolicyoftheOfficeofTissuesandAdvancedTherapiesattheFoodandDrugAdministration’sCenterforBiologicsEvaluationandResearch(FDA/CBER).HeservedattheFDAinvariouspositions,andwasheavilyinvolvedinpolicydevelopmentfortissueengineering,regenerativemedicine,andalternativestoanimaluseinregulatorydecisionmaking.Inadditiontodevelopmentofrisk-basedregulatoryoversightparadigmswithinFDA,hisinterestsincludedbroadereffortstocreateaninterlockingnetworkofinteragencyeffortstofostergrowthofbasicandtranslationalsciencetosupportmaturationoftheoverlappingfieldsoftissueengineeringandregenerativemedicinefrom
primarilydiscoverysciencetowardastageofcommercialdevelopment.Dr.McFarland,Ph.D.,M.D.receivedhisB.S.,Ph.D.,andM.D.fromtheUniversityofNorthCarolinaatChapelHill,andcompletedhisanatomic/clinicalpathologyresidencyandimmunopathologyfellowshiptrainingatUTSouthwesterninDallas.ImmediatelypriortojoiningtheFDA,hewasonthefacultyofthePathologyDepartmentoftheUniversityofTexasSouthwesterninDallas.InadditiontoFDApolicydocumentshehasco-authoredover25articlesinpeer-reviewedarticlesjournalsincludingNature,theProceedingsoftheNationalAcademyofScience(PNAS),andBlood.
B.LynnAllen-Hoffmann,PhDisaProfessor,DepartmentofPathologyandDepartmentofSurgery,UniversityofWisconsin-Madison,andSeniorVicePresidentofRegenerativeMedicine,StratatechCorporationaSubsidiaryofMallinckrodt.Dr.Allen-Hoffmannreceivedherbachelor’sdegreefromtheUniversityofIllinoisandreceivedherPh.D.fromCornellUniversityinIthaca,NewYork.Dr.Allen-HoffmannwasaDamon-RunyonWalter-WinchellPostdoctoralFellowattheDana-FarberCancerInstituteatHarvardMedicalSchoolwhereshestudiedhumankeratinocytegrowthanddifferentiation.Sheisatenured,fullProfessorintheDepartmentsof
FutureofAdvancedBiomanufacturingSessionIIFriday–7:00PM
CurrentAdvancesinBiomanufacturingSessionSaturday–8:00AM
RichardMcFarland,MD,
PhDChiefRegulatoryOfficer,
AdvancedRegenerativeMedicineInstitute/BioFabUSA
Friday,August18,20177:35–8:10PM
MadisonIBMES-ABioM20179
KEYNOTESPEAKERS
PathologyandLaboratoryMedicineandSurgeryattheUWSchoolofMedicineandPublicHealth.Sheisinternationallyrecognizedforherinnovativeresearchandclinicaldevelopmentofhumanskinreplacementsincludingtheworld’sfirstgenetically-enhancedhumanskinreplacements.TheNIKScells,discoveredinherU.W.laboratory,areaconsistentsourceofgeneticallyuniform,non-tumorigenic,pathogenfreehumankeratinocytesamenabletogeneticmanipulation.Asaresultofthediscoveryinherlaboratory,Dr.Allen-HoffmannfoundedStratatechCorporationtodelivercell-basedtherapiestopatientswithcomplexskinloss.ShehasreceivednumerousstateandnationalawardsandisthefirstwomanattheUWtostartabiotechnologycompany.Dr.Allen-Hoffmannhascontributedtonumerouspeer-reviewedpublicationsandpatents.Dr.Allen-Hoffmann’sbasicandclinicalresearchhasreceivedcontinuousresearchsupport,includinggrantsfromtheNIH,NIST,AFIRM,BARDA,andDOD.RecentlyStratatechCorporationhasbeenoneofthetop10companiestoreceiveSBIRandSTTRfundingintheUnitedStates.In2015,BARDAreleasedasolicitationthroughProjectBioShieldforthelatestageclinicaldevelopmentanduseofcell-basedtherapiesforskinreplacementcausedbythermalburnsintheeventofamasscasualtyeventresultingfromthedetonationofanimprovisednucleardevice.StratatechwastheonlyacademicorprivatesectororganizationintheUnitedStatestosuccessfullycompeteforaBioShieldaward.The$247millionProjectBioShieldawardwillenabletheNIKStechnologytobeusedpriortoFDAapprovalthroughtheFDA’sPre-EmergencyUseAuthorizationmechanism.Stratatechreceived
a2016TibbittsAwardwhichwasacceptedbyDr.Allen-HoffmannataWhiteHouseceremony.StratatechCorporationwasacquiredbyMallinckrodtSpecialtyPharmaceuticalsonAugust31,2016.DavidSmithjoinedCambrexBioproductsinJanuary2012astheBusinessUnitDirectoroftheemergingcelltherapycontractmanufacturingbusiness.In2004,hewaspromotedtoVicePresident,BusinessDevelopment,andinDecember2005toVicePresident,CellularTherapeutics.Inthisrole,heassumedresponsibilityforcontractmanufacturing,processdevelopment,andclinical/commercialdevelopmentofCambrex-ownedEngineeredSkinSubstitute(ESS)forcatastrophicburns.In2009,twoyearsfollowingLonza’sacquisitionofCambrexBioproducts,Mr.SmithbecameHeadofTherapeuticCellSolutionswithadditionalresponsibilitiesforbiotherapeuticmedia,processdevelopment,viralvaccinesandgenetherapies.In2015,Mr.Smithbecame
B.LynnAllen-Hoffmann,PhD
ProfessorofPathology&SurgeryUniversityofWisconsinMadison
SeniorVicePresidentStratatechCorporation
Saturday,August19,20178:00–8:35AM
DavidSmith,MBA
VicePresident,GlobalBusinessDevelopment
Lonza
Saturday,August19,20178:35–9:10AM
MadisonIBMES-ABioM201710
KEYNOTESPEAKERS
VicePresident,GlobalBusinessDevelopment,focusingonstrategicagreementsandalliancesfortheEmergingTechnologiesBusinessUnit,whichincludescellandviraltherapy.Heisanactivememberofnumerousgovernmentexpertpanels;companyexecutivecommitteesandadvisoryboards.UnderMr.Smith’sleadershipthecelltherapycontractmanufactacturingbusinessasgrownfromstart-uptomarketleader.PriortojoiningCambrex,Mr.SmithwasVicePresident,CorporateDevelopmentatClaragen,Inc.andBusinessUnitDirectoratInvitrogen.
Mr.DavidSmithholdsaB.S.inPharmacyfromDuquesneUniversityinPittsburgh,PennsylvaniaandaM.B.A.fromWheelingJesuitUniversityinWheeling,WestVirginia.Dr.WeiSuniscurrentlyappointedAlbertSoffaChairProfessorofMechanicalEngineeringatDrexelUniversity,USA,andNational“Thousand-Talent”DistinguishedProfessorandDirectorofBiomanufacturingResearchCenteratTsinghuaUniversity,China.HisresearchhasbeenonBiofabrication,3DBio-Printing,Computer-AidedTissueEngineering,andAdditiveManufacturing.HisresearchhasbeensponsoredbyNationalScienceFoundation(NSF),DefenseAdvancedResearchProjectsAgency(DARPA),NationalAeronauticsandSpaceAdministration(NASA),ChineseNaturalScienceFoundation(CNSF)andChineseMinistryofScienceandTechnology.Hehaspublishedover350journalandconferencepapers/abstractsandconductedover250nationalandinternationalinvited
presentationsinthefieldofhisresearch.HeiscurrentlyservingEditor-in-ChiefforjournalBiofabrication.
Dr.MichaelJ.YaszemskiistheJohnandPosyKrehbielEndowedProfessorofOrthopedicSurgeryandBiomedicalEngineeringattheMayoClinicanddirectorofitsPolymericBiomaterialsandTissueEngineeringLaboratory.HeisaretiredU.S.AirForceBrigadierGeneralandservedintheofficeoftheAirForceSurgeonGeneralandtheofficeofthePresidentoftheUniformedServicesUniversityoftheHealthSciencespriortoretiringin2013.Heservedas
FutureAdvancesinBiomanufacturingSession
Saturday–8:00AM
WeiSun,PhD
AlbertaSoffaChair&ProfessorofMechanicalEngineering
DrexelUniversity
National“Thousand-Talent”DistinguishedProfessorTsinghuaUniversity
Saturday,August19,20179:10–9:45AM
MichaelYaszemski,
MD,PhDJohnandPosyKrehbielEndowedProfessorofOrthopedicSurgeryandBiomedicalEngineering
MayoClinic
Saturday,August19,201710:00–10:35AM
MadisonIBMES-ABioM201711
2017ABIOMAW
ARDRECIPIENTS
presidentoftheMayoClinicmedicalstafffrom2013-2014,andhadservedfor10yearsastheChairoftheSpineSurgeryDivisionatMayopriortoenteringthepresidentialline.HereceivedbothBachelor’sandMaster’sdegreesinChemicalEngineeringfromLehighUniversityin1977and1978,anM.D.fromGeorgetownUniversityin1983andaPh.D.inChemicalEngineeringfromtheMassachusettsInstituteofTechnologyin1995.HeorganizedandthenservedasthefirstChairoftheMusculoskeletalTissueEngineeringstudysectionatNIH,andservedasamemberoftheAdvisoryCounciloftheNationalInstituteofBiomedicalImagingandBioengineeringfrom2010-2014.Hebegana4yeartermasamemberoftheAdvisoryCounciloftheNationalInstituteofArthritis,Musculoskeletal,andSkinDiseasesatNIHin2017.HeservedasChairoftheFDACenterforDevicesandRadiologicHealthAdvisoryCommittee,andiscurrentlyamemberoftheFDAScienceBoard.HecompletedasixyeartermontheLehighUniversityBoardofTrusteesin2017.Hisclinicalpracticeencompassesspinesurgeryandmusculoskeletaloncology.Hisresearchinterestsareinthesynthesisandcharacterizationofnoveldegradablepolymersforuseinboneregeneration,cartilageregeneration,nervoustissueregeneration,andcontrolleddeliveryofchemotherapeuticagentstomusculoskeletaltumors.
heABioM-SIGrecognizesthefollowingscientistfortheiroutstandingresearchdevelopingnext-generationbiomanufacturingproductsandprocesses.
JuniorInvestigatorAwardAndrewDias,PhD UniversityofWisconsinMadison
MinglinMa,PhD CornellUniversity
Jae-WonShin,PhD UniversityofIllinoisChicago
XiaojunLian,PhD ThePennsylvaniaStateUniversity
GraduateStudentTravelAwardAngelaXie,PhD UniversityofWisconsinMadisonEmergingConceptsAwardTiffanyHeaster UniversityofWisconsinMadison
FerdousFinklea AuburnUniversity
CarlosR.Marti-Figueroa UniversityofWisconsinMadison
T
MadisonIBMES-ABioM201712
ABSTRACTREVIEWERS
GENERALIN
FORM
ATION
SeanPalecek UniversityofWisconsinMadison
KrishanuSaha UniversityofWisconsinMadisonLih-ShengTurng UniversityofWisconsinMadisonKartikBalachandran UniversityofArkansas
KristenBilliar WorcesterPolytechnicInstitute
LesleyChow LehighUniversity
MatthewFisher NorthCarolinaStateUniversity
YiHong UniversityofTexasatArlington
DebanjanSarkar SUNYBuffalo
RandolphAshton UniversityofWisconsinMadisonWilliamMurphy UniversityofWisconsinMadisonKaimingYe SUNYBinghamton
RolandKaunas TexasA&MUniversity
GlennGaudette WorcesterPolytechnicInstituteElizabethLipke AuburnUniversity
MeetingLocationWisconsinInstitutesforDiscovery330N.OrchardStreetMadison,WI53715608.316.4300RegistrationPaidregistrationisrequiredforadmissiontoallmeetingfunctions.Registrationcanbecompletedonline,https://www.regonline.com/registration/Checkin.aspx?EventID=2004087,oronsitefrom7:30-5:00pmonFriday,August18.ExhibitsandPosterSessionExhibittablesandpostersshouldbeset-upby8:30amonFriday,August18andtakendownby1:30pmonSaturday,August19.Posterlocationswillbelabeledcorrespondingtoyourlistingnumber(p.15).
ThankYoutoourReviewersfortheirTimeandEffort
MadisonIBMES-ABioM201713
GENERALIN
FORM
ATION
PlatformPresenterInformationPresentationlecternwillbeequippedwithaPClaptoporpresenterswillbeabletoconnecttheirownlaptops.AVStaffwillbeonhandtoassist.Duringthebreakbeforeyoursessionbegins,pleaseuploadyourpresentationontothecomputerusingamemorystickorflashdrive.Ifusingapersonallaptop,youshouldtesttheconnectionandpresentationduringthistimeframeaswell.Allpresentationswillbedeletedattheendoftheconference.Apresentationcount-downtimerwillbepresentatthebackofthelecturehall.Pleaseremainwithinyourallottedtimeslots,andleavetimeforquestions.WIFIFreewifiisavailablethroughthe‘TownCenter’network.VenueMap
MadisonIBMES-ABioM201714
POSTERSESSIO
N
1 Engineering2-DHumanCNSTissueSlicesfromHumanPluripotentStem
CellsAlirezaAghayee1,GavinKnight1,BradyLudin1,RandolphAshton11UniversityofWisconsinMadison,Madison,WI
2 MonitoringandmodelingofT-cellphenotypedistributionthroughisolationand50-foldexpansionAmritavaDas1,NicoleJPiscopo1,KatherinePMueller1,KirstiWalker1,ChristianCCapitini1,KrishanuSaha11UniversityofWisconsinMadison,Madison,WI
3 IntegrationofInkjetPrintedMicrovasculatureintoHostTissuesBeuOropeza1,LuisSolis1,MariaYanez2,ThomasBoland11UniversityofTexasatElPaso,ElPaso,TX,2UniversityofSouthCarolina,Columbia,SC
4 ScalableproductionofosteogenicdecellularizedtissuederivedfrommesenchymalstemcellsforbonetissueengineeringC.Sears1,E.McNeill2,B.Clough2,S.Jaligama1,J.Kameoka1,C.A.Gregory1,2,R.Kaunas1,21TexasA&MUniversity,2TexasA&MHealthScienceCenter,CollegeStation,TX
5 DevelopmentofBiomimeticThermoplasticPolyurethane/FibroinSmall-DiameterVascularGraftsviaNovelElectrospinningApproachEmilyYu1,JueZhang2,Hao-YangMi1,JamesA.Thomson1,2,Lih-ShengTurng11UniversityofWisconsinMadison,2MorgridgeInstituteforResearch,Madison,WI
6 Ahighthroughputtissue-modelmanufacturingsystemFrankBenesch-Lee1andKristenL.Billiar11WorcesterPolytechnicInstitute,Worcester,MA
7 Self-assemblyofhumanembryonicstemcell-derivedendothelialcellsinto
threedimensionalvascularscaffoldsindynamic,syntheticmicroenvironmentsGauravKaushik1,DanielA.Gil2,ElizabethTorr1,ElizabethS.Berge2,CherylSoref1,PeytonUhl1,GianlucaFontana1,JessicaAntosiewicz-Bourget2,CollinEdington3,MichaelP.Schwartz1,BrianJohnson1,LindaG.Griffith3,JamesA.Thomson2,MelissaC.Skala2,WilliamT.Daly1,WilliamL.Murphy11UniversityofWisconsinMadison,2MorgridgeInstituteforResearch,Madison,WI,3MassachusettesInstituteofTechnology,Cambridge,MA
MadisonIBMES-ABioM201715
POSTERSESSIO
N
8 BiofunctionalizedPlantsasDiverseBiomaterialsforHumanCellCulture
GianlucaFontana1,JoshuaGershlak2,MichalAdamski1,Jae-SungLee1,ShionMatsumoto2,HauD.Le1,BernardBinder1,JohnWirth3,GlennGaudette2,WilliamL.Murphy11UniversityofWisconsinMadison,Madison,WI,2WorcesterPolytechnicInstitute,Worcester,MA,3OlbrichBotanicalGardens,Madison,WI
9 Three-dimensionaltissuesusinghumanpluripotentstemcellspheroidsasbiofabricationbuildingblocksHaishuangLin1,QiangLi1,YuguoLei11UniversityofNebraska,Lincoln,NE
10 Biocompatible,DegradableThermoplasticPolyurethaneBasedonPolycaprolactone-Block-Polytetrahydrofuran-Block-PolycaprolactoneCopolymerforSoftTissueEngineeringHao-YangMi1,XinJing1,2,BrettN.Napiwocki1,BreannaS.Hagerty1,GuojunChen1,Lih-ShengTurng11UniversityofWisconsinMadison,Madison,WI,2SouthChinaUniversityofTechnology,Guangzhou,China
11 PrecisegeneeditingofhumanstemcellsusingnovelnanoparticlescontainingCRISPRnucleaseswithDNArepairtemplatesJaredCarlson-Stevermer1,AmrA.Abdeen1,LucilleKohlenberg1,MadelynGoedland1,KaivalyaMolugu1,MengLou1,KrishanuSaha11UniversityofWisconsinMadison,Madison,WI
12 Leaf-inspiredArtificialMicrovascularNetworks(LIAMN)forThree-dimensionalCellCultureJiandiWan1,RongFan1,YihangSun11RochesterInstituteofTechnology,Rochester,NY
13 MaturationofhPSC-derivedCardiomyocytesviaCoculturewithEndothelialCellsKaitlinK.Dunn1,IsabellaReichardt1,SeanP.Palecek11UniversityofWisconsinMadison,Madison,WI
14 MicropatternedsubstratestopromoteanddissectreprogrammingofhumansomaticcellsTyHarkness1,JaredCarlson-Stevermer1,RyanPrestil1,StephanieSeymour1,GavinKnight1,KaivalyaMolugu1,RandolphAshton1,KrishanuSaha11UniversityofWisconsinMadison,Madison,WI
MadisonIBMES-ABioM201716
POSTERSESSIO
N
15 EngineeringAnisotropicJanus-typePolymerNanofiberScaffoldsvia
CentrifugalJetSpinningPrashanthRavishankar1,AlexKhang1,KartikBalachandran11UniversityofArkansas,Fayetteville,AR
16 AMicroscaleTestbedtoAssaytheManufactureofCART-Cell
ImmunotherapiesNicoleJPiscopo1,KatherinePMueller1,AmritavaDas1,KrishanuSaha11UniversityofWisconsinMadison,Madison,WI
17 GMPCas9Nuclease:manufacturingreproducibilityandavailabilityPeteLeland1,NicoleKavanaugh1,ShannonBrink11Aldevron,Fargo,NDandMadison,WI
18 BioprintingdefinedheterogeneouscellularmicroenvironmentsPeterNewman1,Jae-WonShin1,HalaZreiqat21UniversityofIllinoisChicago,Chicago,IL,2UniversityofSydney,Australia
19 BiofabricationofTissueEngineeredVesselGrafts
SebastianFreeman1,LuxiZhou1,KyleReeser1,ShaJin1,andKaimingYe11SUNYBinghamton,Binghamton,NY
20 DirectedDifferentiationofHumanPluripotentStemCellstoPodocytesvia
WntActivationTongchengQian1,EricV.Shusta1,SeanP.Palecek11UniversityofWisconsinMadison,Madison,WI
21 FabricationofStableCollagenScaffoldsforHumanPluripotentStemCellsXiangyangLyu1,KaimingYe1,ShaJin11SUNYBinghamton,Binghamton,NY
22 FabricationandCharacterizationofDirect-writeGelatin/PLGAMicro-fibersforPotentialMicrovascularTissueAngiogenesisXiaomingFan1,MarkCrain1,HanwenYuan1,RobertS.Keynton11UniversityofLouisville,Louisville,KY
23 Mussel-InspiredChitosan/GrapheneOxideHydrogelwithRapidSelf-HealingandRecoveryBehavioratRoomTemperatureXinJing1,Hao-YangMi1,BrettN.Napiwocki1,Lih-ShengTurng11UniversityofWisconsinMadison,Madison,WI
MadisonIBMES-ABioM201717
POSTERSESSIO
N
24 Micro-structuredphotoreceptorscaffoldsformodelingandtherapeutic
applicationsYeiHwanJung1,M.JosephPhillips2,JuhwanLee1,ShaoqinGong1,DavidM.Gamm1,ZhenqiangMa11UniversityofWisconsinMadison,Madison,WI
25 Endothelial-likeCellsDifferentiatedfromMesenchymalStemCellsModulatedbyStiffnessofCultureSubstratesYong-ChaoJiang1,2,Ming-SongLee2,Hong-LiJiao2,QianLi1,Lih-ShengTurng2,Wan-JuLi21ZhengzhouUniversity,Zhengzhou,China,2UniversityofWisconsinMadison,Madison,WI
26 EncapsulationofEquineEndothelialColonyFormingCellsinInjectableHydrogelMicrospheresusingaNovelMicrofluidicSystemYuanTian1,WenJ.Seeto1,RandolphL.Winter1,FredCaldwell1,AnneA.Wooldridge1,ElizabethA.Lipke11AuburnUniversity,Auburn,AL
27 AnIntegratedandAutomatedMiniatureDeviceforPersonalizedHumanInducedPluripotentStemCellExpansionandDifferentiationHaishuangLin1,QiangLi1,YuguoLei11UniversityofNebraska,Lincoln,NE
28 Designofa3DprintingsystemtofabricatetherapeuticallyloadedbiopolymermicrothreadscaffoldswhichfacilitateskeletalmuscleregenerationinamodelofvolumetricmusclelossMeaganCarnes1,ChristopherNycz1,JeremyShui1,JacquelineClaveaux1,AlexanderMarkoski1,RichardEberheim1,GregoryFischer1,RaymondL.Pins1,GeorgePins11WorcesterPolytechnicInstitute,Worcester,MA
29 CarbonNanotubeBasedOpticalSensorsforBiomanufacturingNigelF.Reuel1andNathanielKallmyer11IowaStateUniversityofScienceandTechnology,Ames,IA
30 MechanicalPropertiesTestingtoCharacterizeandDevelop3DCell
CultureTechnologies YiWenChai1,BethA.Lindborg1,2,JohnH.Brekke1
1BRTILifeSciences,TwoHarbors,MN,2UniversityofMinnesota,TwinCities,MN
MadisonIBMES-ABioM201718
PROGRAM
-AT-A-GLANCE
31 RapidStereolithographyPrintingofHuman-scaleVascularizedTissue NandithaAnandakrishnan1,HangYe1,ChiZhou1,RuogangZhao1
1SUNYBuffalo,Buffalo,NY
32 DevelopmentofanimplantablecontractilecardiacbundleusinghPS-CMandfibrinmicrothreads
KatrinaHansen1,EmilyRobbins1,GlennGaudette11WorcesterPolytechnicInstitute,Worcester,MA
33 Sustainedreleasefrommineral-coatedmicroparticlesreducesrequiredbFGFforhPSCculture
HunterJohnson1,AndrewKhalil1,AngelaXie1,andWilliamMurphy11UniversityofWisconsinMadison,Madison,WI
AllconferenceeventswillbeheldintheH.F.DeLucaForumandtheMainandCentralOpenCourt,exceptforABioMPlanningCommitteeBusinessMeetingsthatwillbeheldinconferenceroom1170.
Thursday,August17,2017
7:00pm-9:00pm ABioMPlanningCommitteeBusinessMeeting
Friday,August18,2017
7:30am-5:00pm Registration
8:00am-5:00pm ExhibitionTables
8:00am-8:30am Networking/LightBreakfastFare
8:30am-8:40am OpeningRemarks
StatusofAdvancedBiomanufacturingSession
8:40am-9:15am
TheDigitalTwin:TowardBioreactorModelingUsingDeepAnalyticsPaulGoodwin,PhD,ScienceDirector,LifeSciences–ChiefTechnologyOfficer,GEHealthcare
9:15am-9:50amBiomanufacturingforSkeletalMuscleRepair,RegenerationandReplacementGeorgeChrist,PhD,MaryMuilenbrrgStampProfessorof
Program-at-a-Glance
MadisonIBMES-ABioM201719
PROGRAM
-AT-A-GLANCE
OrthopaedicSurgery&Co-DirectoroftheCenterforAdvancedBiomanufacturing,UniversityofVirginia
9:50am-10:25am
Manufacturingaclinicallycompatiblehumanembryonicstemcell-derivedmidbraindopamineprogenitorandneuroncellproduct,MSK-DA01MarkJ.Tomishima,PhD,Head,SKIStemCellResearchFacility,SloanKetteringInstitute
10:25am-10:50am CoffeeBreakandNetworking
EmergingConceptsSession
10:50am-11:25am
BiofabricationandBiomanufacturing:WhereBiologyMeetsEngineeringDeepakVashishth,PhD,Professor&DirectoroftheCenterforBiotechnologyandInterdisciplinaryStudies,RensselaerPolytechnicInstitute
11:25am-11:40am
ChemicallyDefinedLabileSubstratesforControlledSelf-assemblyofStemCellAggregatesAngelaXie,UniversityofWisconsin-Madison(GraduateStudentTravelAwardWinner)
11:40am-11:55am
ImagingApproachesforQualityControlofAdoptiveImmuneCellTherapiesTiffanyHeaster,UniversityofWisconsin-Madison(EmergingConceptsAwardWinner)
11:55am-12:10pm
ANovelMicrofluidicDevicefortheProductionofEngineeredCardiacTissueSpheroidsFerdousFinklea,AuburnUniversity(EmergingConceptsAwardWinner)
12:10pm-12:25pm
Engineering3-DOrganoidMorphologyusingPVOH-CaSacrificialTemplatesCarlosMarti-Figueroa,UniversityofWisconsin–Madison(EmergingConceptsAwardWinner)
12:25pm-1:25pm NetworkingandLunch
FutureofAdvancedBiomanufacturingSessionI
1:25pm-2:00pm
KeyconsiderationsinLargeScale,Low-CostManufacturingofHighQualityTherapeuticCells:AperspectivefromtheNationalCellManufacturingConsortiumKrishnenduRoy,PhD,ProfessorandRobertA.Milton
MadisonIBMES-ABioM201720
PROGRAM
-AT-A-GLANCE
Chair&DirectorofMarcusCenterforCell-TherapyCharacterizationandManufacturing(MC3M),GeorgiaInstituteofTechnology
2:00pm-3:00pm
FutureofAdvancedBiomanufacturing‘Unconference’:TopicsincludeCellManufacturing,Organ/OrganoidEngineering,SustainableAdvancedBiomanufacturing,RegulatoryIssuesinBiomanufacturing.Moderator:GlennGaudette,PhD,Professor,WorcesterPolytechnicInstitute
3:00pm-3:30pm Unconferencereportout
3:30pm-3:45pm NetworkingandCoffeeBreak
Industry&AcademiaCollaborationsPanelDiscussion
3:45pm-4:45pm
“Howdowecreatecollaborationswithvalueforindustry&academia?”
§ Moderator:RolandKaunas,PhDAssociateProfessor,TexasA&MUniversity
§ Panelist:TomFoti,VicePresident&GeneralManager,Aldevron
§ Panelist:SteveKattman,Director,CardiacCellTherapy,CellularDynamicsInternational
§ Panelist:MarkPowers,PhD,SeniorDirector,R&DofCellBiology,ThermoFisherScientific
§ Panelist:GangBao,PhD,FoytFamilyProfessor,RiceUniversity
§ Panelist:ChengDong,PhD,DistinguishedProfessor&DepartmentofBiomedicalEngineeringHead,PennStateUniversity
PosterPresentationsSession
4:45pm-5:00pmPostersSpotlights:JaredCarlson-Stevermer,AlirezaAghayee,GauravKaushik,XiaomingFan
5:00pm-6:00pm PosterSession(HorsD’oeuvresandBeverages)
6:00pm-7:00pm NetworkingandDinner
FutureofAdvancedBiomanufacturingSessionII
7:00pm-9:00pm DessertsandCoffee
MadisonIBMES-ABioM201721
PROGRAM
-AT-A-GLANCE
7:00pm-7:35pm
Wisconsin’sFutureBiomanufacturingCenterofExcellenceLisaJohnson,ChiefExecutiveOfficer,BioForwardWilliamMurphy,PhD,HarveyD.SpanglerProfessor&Co-DirectorofStemCellandRegenerativeMedicineCenter,UniversityofWisconsin–Madison
7:35pm-8:10pm
TheBirthofBioFabUSA:ManufacturingtheFutureofBiofabricationRichardMcFarland,MD,PhD,ChiefRegulatoryOfficer,TheAdvancedRegenerativeManufacturingInstitute
Saturday,August19,2017
7:00am-8:00am ABioMPlanningCommitteeBusinessMeeting
7:30am-12:00pm ExhibitionTables
7:30am-8:00am NetworkingandLightBreakfast
CurrentAdvancesinBiomanufacturingSession
8:00am-8:35am
StrataGraft®BiomanufacturingFromDiscoverytoPhaseIIIClinicalTrialB.LynnAllen-Hoffmann,PhD,Founder/ChiefExecutiveOfficer/ChiefScientificOfficer,Stratatech&Professor,UniversityofWisconsin–Madison
8:35am-9:10amAPathtoSuccessfulCommercialManufacturingDavidSmith,PhD,VicePresidentforGlobalBusinessDevelopment,Lonza
9:10am-9:45am3DBioprintingforinvitroTissueModelsWeiSun,PhD,AlbertaSoffaChair&Professor,DrexelUniversity
9:45am-10:00am NetworkingandCoffeeBreak
FutureAdvancesinBiomanufacturingSession
10:00am-10:35am
BiofabricationofMusculoskeletalRegenerativeMedicineProductsMikeYaszemski,MD,PhD,ProfessorMayoClinics
10:35am-10:50amBiomimetic3DMicroenvironmentsInRegenerativeMedicine:MechanicalEngineeringMeetsBiochemistryAtTheMolecularLevel
MadisonIBMES-ABioM201722
PROGRAM
-AT-A-GLANCE
JohnH.Brekke,DDS,ChiefScientificOfficerofBRTILifeSciences-CellMate3D
10:50am-11:05am
SyntheticanddegradablehydrogelmicrocarriercoatingsforstemcellexpansionAndrewDias,PhD,UniversityofWisconsin-Madison(JuniorInvestigatorAwardWinner)
11:05am-11:20am
Organogenesisinmicrocapsules:AscalableplatformfororganoidcultureandmanufacturingMinglinMa,PhD,AssistantProfessor,CornellUniversity(JuniorInvestigatorAwardWinner)
11:20am-11:45amLeveragingbiomaterialmechanicstodesignmesenchymalstemcelltherapiesJae-WonShin,PhD,AssistantProfessor,UniversityofIllinoisatChicago(JuniorInvestigatorAwardWinner)
11:45am-12:00pm
BiomanufacturingHumanVentricularProgenitorsforinvivoorgan-on-organcardiactissueengineeringXiaojunLian,PhD,AssistantProfessor,PennStateUniversity(JuniorInvestigatorAwardWinner)
12:00pm-1:00pm
WorkforceTraininginAdvancedBiomanufacturingSession(BoxLunch)
§ Moderator:KaimingYe,PhD,Professor&ChairBinghamtonUniversity
§ Panelist:TomTubon,PhD,ProjectDirector/PI,NSFATEStemCellEducationInitiative.MadisonAreaTechnicalCollege
§ Panelist:WilliamMurphy,PhD,HarveyD.SpanglerProfessor&Co-DirectorofStemCellandRegenerativeMedicineCenter,UniversityofWisconsin–Madison
§ Panelist:SusanL.Woodard,PhD,NationalCenterforTherapeuticsManufacturing,SusanL.Woodard,PhD,TexasA&M
§ Panelist:KamalA.Rashid,Ph.D.Director,BiomanufacturingEducation&TrainingCenter,WorcesterPolytechnicInstitute
§ Panelist:WilliamJ.King,PhD,PrincipalResearchScientist,ZimmerBiomet
1:00pm-1:10pm ConclusionRemarks