2012 RD Pipeline_Vegetables Sridhar

8/12/2019 2012 RD Pipeline_Vegetables Sridhar

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Seminis is a registered trademark of Seminis Vegetable Seeds, Inc. De Ruiter is a trademark of Monsanto Invest NV. Monsanto and Vine Design is a registeredtrademark of Monsanto Technology LLC. 2011 Seminis Vegetable Seeds, Inc.

2 0 1 2

R &D

P i p e l i n e

THE FUTURE OFVEGETABLES


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Family Crops

Solanaceous Tomato, rootstock, pepper, eggplant

Cucurbits Squash, cucumber, melon, watermelon,pumpkin

Root and Bulb Onion, carrot, leek

Large Seed Sweet corn, garden bean

Brassica Broccoli, cauliflower, cabbage, radish,Chinese cabbage

Leafy Lettuce, spinach, fennel

Monsantos Vegetable Seed Crops


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Growers are Seeking InnovationNORTH AMERICAN GROWER Any time we get new products or newseeds or new varieties, it's throughresearch and innovations. So meaningfulinnovation is telling me Seminis isworking to bring new products andpushing for new and better. It's a directimpact on our success it says

it all.

DUTCH GROWER

This is exactly what we need. Avisionary on market needs and acompany that is driven to innovatewith you and for you, developing newproducts together.


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Industry-Leading R&D Organization Helps MonsantoVegetable Seeds Deliver Innovative Products to Growers andConsumers

Over 50 Breeding & Testingstations in 19 countriesrepresenting all major marketsand climates

Dozens of Plant Breeders evaluating germplasm from allover the world to find importanttraits like disease resistance

Generating 10s of millions ofmarker data points yearly tohelp breeders select the mostdesirable plants for newproducts faster


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Faster Product Development Tools, Capability andCapacity Enable Successful Discovery as Never Before

START: 12 BREEDING POPULATIONSReflects typical need to cover environments and markets

START: 12 BREEDING POPULATIONSReflects typical need to cover environments and markets

Breeder evaluates100 plants:7 selected

Selected based onfirst resistance:

3 selected

Selected basedon secondresistance:0 selected

Traditional Breeding

Outcome: 4.18 x 10 -13 Probability of Success

0

Advanced Breeding Techniques

Rapid-cyclenursery creates6,400 seedlings

Marker lab findstriple-resistant

plants:100 selected

Breeder evaluates100 plants:7 selected

Outcome: 98% Probability of Success


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Vegetable Breeding Guided by MarkersMapped to Genes of Interest

Thousands of Markers acrossCrops

More than 180 Key Traits are Linked to Markers, Enabling RapidBreeding of Improved Crops


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Ramping Up Seed Chipping to HelpSpeed Delivery of Over a Dozen Key

Traits in Cucumber and Melon

Similar to corn and soybeans, seed chipping helps simplify and speed up thevegetable breeding process

Program has tripled in scale since 2010, supporting cucumber, melon andwatermelon breeding

Seeds preciselypositioned Seed clipping


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Key Phases in Vegetable Breeding

DISCOVERY PHASE 1Proof of Concept

PHASE 2Early Development

PHASE 3AdvancedDevelopment

PHASE 4Pre-launch

Phenotypic AssayDevelopment

Trait Source

Identification

DemonstrateMode andEfficacy of TraitGenetics

Trait-linkedMarkerIdentification

Inbred LineDevelopment

GeneticRefinement

Demonstrate

BroadGermplasmEfficacy

Initiate HighThroughputSelection

Screening Trials(SC1 & SC2)

ProductPerformanceTesting (PCM 1and 2)

Foundation SeedIncrease ofFinished Parent

Product Pre-commercialTesting (PCM 3and 4)

Seed Bulk-up

Pre-marketing

Average Duration12 24 months



Average Duration12 - 24 months


Time estimates are based on our experience; they can overlap. Total development time for any particular product may be shorter or longer than the time estimated here.


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Seminis EasyHarvest Broccoli Could Improve BothHarvest Efficiency and Consumer Appeal Compared toConventional Varieties

Phase 4Pre-Launch

Several key features to helpmake harvest easier

Raised head even with leafcanopy

Fewer leaves on stem tohand-strip

Uniform maturity couldreduce passes through field

Consistently greener floretsimproves consumer appeal

United Kingdom October 2009


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Downy Mildew Resistance Would Improve Grower Returns inMultiple Varieties of Slicing Cucumber

SUSCEPTIBLE RESISTANT

Phase 4Pre-Launch

Molecular breeding allows quick addition of resistance toother cucumber market types

Opportunity to reduce costly fungicide chemicalapplications for disease control

Resistant American Slicer cucumber

varieties on track for 2012 launch

SUSCEPTIBLE RESISTANT

Resistant Beit Alpha cucumber

varieties in development (Phase 4)


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Broadly Applying Marker Assisted Breeding to ImproveResistance to Phytophthora , One of the Most DestructivePepper Diseases Globally

Phase 3Adv. Development

Phytophthora resistance incorporatedinto a broad range of pepper typesthrough advanced breeding techniques

AnchoAnchoAnchoAncho

GuajilloGuajilloGuajilloGuajillo

BlockyBlockyBlockyBlocky

JalapeoJalapeoJalapeoJalapeo

DONORDONORDONORDONOR

PasillaPasillaPasillaPasillaAnaheimAnaheimAnaheimAnaheim

CayenneCayenneCayenneCayenne

SerranoSerranoSerranoSerrano

Field evaluations demonstrate significantimprovements in Phytophthora resistance

Sahuaro Anaheim Pepper Type

ORIGINALPHYTOPHTHORA

RESISTANT

Santa Fe GrandeSanta Fe GrandeSanta Fe GrandeSanta Fe Grande


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Geminivirus Resistance Would Protect Tomatoes againsttheir Most Significant Disease Threat

Phase 2Early Development

Opportunity to improve marketable yield and fruit quality underdisease pressure

Working to combine multiple resistance sources into elite germplasmto provide best protection package

SUSCEPTIBLE VARIETY RESISTANT VARIETY


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Vegetable Innovation for ConsumersOur mission is to improve grower productivity , as well as increaseworldwide consumption of fruits and vegetables , by developingnew products through breeding and nutritional science innovation .

Mon Veg Consumer Research (2008) US & EU-5 Consumer Preference for Fresh VegetablesCommercial Products

e . g .

e . g .

e . g .

e . g .

SensoryExperience

Taste / Aroma / FlavorColorTexture

Nutrition &Health

Raised nutrient densityIncrease consumption byimproving flavor

ConvenienceFreshnessShelf lifeFresh cut


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A Better Eating Experience Would Be Deliveredwith Frescada Lettuce

A sweet tasting lettuce, very low inbitterness and crunchier compared totraditional Romaine

Greener color and more flavor

compared to iceberg Preferred by many consumers in blind

taste tests

Currently trialing as specialty products;

Second generation varieties to expandmarket opportunity are near launch

Phase 4Pre-Launch


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Certain statements contained in this presentation are "forward-looking statements," such as statementsconcerning the company's anticipated financial results, current and future product performance, regulatory approvals,

business and financial plans and other non-historical facts. These statements are based on current expectations andcurrently available information. However, since these statements are based on factors that involve risks anduncertainties, the company's actual performance and results may differ materially from those described or implied bysuch forward-looking statements. Factors that could cause or contribute to such differences include, among others:continued competition in seeds, traits and agricultural chemicals; the company's exposure to various contingencies,including those related to intellectual property protection, regulatory compliance and the speed with which approvalsare received, and public acceptance of biotechnology products; the success of the company's research anddevelopment activities; the outcomes of major lawsuits and the previously announced SEC investigation; thepreviously reported material weakness in our internal controls over financial reporting; developments related to

foreign currencies and economies; successful operation of recent acquisitions; fluctuations in commodity prices;compliance with regulations affecting our manufacturing; the accuracy of the company's estimates related todistribution inventory levels; the company's ability to fund its short-term financing needs and to obtain payment for theproducts that it sells; the effect of weather conditions, natural disasters and accidents on the agriculture business orthe company's facilities; and other risks and factors detailed in the company's most recent periodic report to the SEC.Undue reliance should not be placed on these forward-looking statements, which are current only as of the date ofthis presentation. The company disclaims any current intention or obligation to update any forward-lookingstatements or any of the factors that may affect actual results.

ALWAYS READ AND FOLLOW PESTICIDE LABEL DIRECTIONS. Asgrow and the A Design , Asgrow, andMonsanto and Vine Design are registered trademarks of Monsanto Technology LLC. EasyHarvest , EverMild &Design, and EverMild are trademarks of Seminis Vegetable Seeds, Inc. All other trademarks are the property oftheir respective owners. Beneforte and Seminis are registered trademarks of Seminis Vegetable Seeds, Inc. DeRuiter Seeds Hybrid Seeds & Design and Melorange are registered trademarks of Monsanto Invest N.V.

2012 Monsanto Company.

Notes

2012 RD Pipeline_Vegetables Sridhar

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