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    [email protected]

    Laboratory LOINC Workshop - Indianapolis, IN

    Introduction and Overview

    mailto:[email protected]:[email protected]:[email protected]
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    http://loinc.org/slideshowshttp://loinc.org/slideshows
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    Acknowledgements

    LOINC Development TeamKathy Mercer, Jaci Phillips, Jami Deckard, Kelly Malott,

    David Baorto, Clem McDonald

    RELMA Development Team

    John Hook, Anandhi Sowmyan, James Dennis

    LOINC Committee

    Sandy Poremba

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    photo via noshaMcDonald et al. Canopy Computing: using the Web in Clinical Practice.JAMA

    . 1998;280(15):1325-1329.

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    7/164photo via noshaMcDonald et al. Canopy Computing: using the Web in Clinical Practice.JAMA. 1998;280(15):1325-1329.

    The rain forest canopy is aseamless web through which

    arboreal creatures efficientlymove to reach the edible

    fruits without any attentionto the individual trees.

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    8/164photo via beckstei

    http://www.flickr.com/photos/beckstei/6269438822/sizes/o/in/photostream/http://www.flickr.com/photos/beckstei/6269438822/sizes/o/in/photostream/
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    40 years of EMR workndiana etwork for atient are

    Arboreal Informatics Pioneers

    Regenstrief

    the Data Switzerland

    Nations most comprehensive and longest tenured HIE

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    Fundamental challenge:Local systems have different ways of

    identifying the same concept.

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    13/164photo via pfarrell95

    http://www.flickr.com/photos/65005341@N03/http://www.flickr.com/photos/65005341@N03/http://www.flickr.com/photos/65005341@N03/
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    A vocabulary standard

    would serve as theRosetta Stone.

    Image Hans Hillewaert /CC-BY-SA-3.0

    http://creativecommons.org/licenses/by-sa/3.0/http://creativecommons.org/licenses/by-sa/3.0/http://creativecommons.org/licenses/by-sa/3.0/http://creativecommons.org/licenses/by-sa/3.0/
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    ogical

    bservation

    dentifiers

    ames and

    odesA universal code system that facilitates exchange,

    pooling, and processing of results

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    Established in 1994 byRegenstrief Institute.

    Vocabulary standard for

    observation identifiers.

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    Similar name, different meaning

    photo via Caption Time

    http://captiontime.tumblr.com/http://captiontime.tumblr.com/
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    Similar name, different meaning

    meerkat meerkat mere cat meerkat

    photo via Caption Time

    http://captiontime.tumblr.com/http://captiontime.tumblr.com/
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    MEASUREMENTS

    US

    R

    photo via puuikibeach

    http://www.flickr.com/photos/puuikibeachhttp://www.flickr.com/photos/puuikibeachhttp://www.flickr.com/photos/puuikibeach
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    If an observation is a question and

    the observation value is

    an answer

    LOINC provides codes for questions Where needed, other vocabularies provide codes for

    answers

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    What is my patients

    hemoglobin level?718-7:Hemoglobin:MCnc:Pt:Bld:Qn

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    How fast does my patient

    usually walk?41959-8:Walking speed:Vel:1W^mean:^Patient:Qn:Calculated

    photo via Ed Yourdon

    http://www.flickr.com/photos/yourdon/http://www.flickr.com/photos/yourdon/http://www.flickr.com/photos/yourdon/
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    Indiana Network for Patient Care

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    Indiana Network for Patient Care

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    Indiana Network for Patient Care

    HL7 v2.x Message

    di k f i

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    Indiana Network for Patient Care

    HL7 v2.x Message

    I di N k f P i C

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    Indiana Network for Patient Care

    HL7 v2.x Message

    I di N k f P i C

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    Indiana Network for Patient Care

    HL7 v2.x Message

    I di N k f P i C

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    Indiana Network for Patient Care

    HL7 v2.x Message

    I di N t k f P ti t C

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    Indiana Network for Patient Care

    HL7 v2.x Message

    I di N t k f P ti t C

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    Indiana Network for Patient Care

    HL7 v2.x Message

    I di N t k f P ti t C

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    Indiana Network for Patient Care

    HL7 v2.x Message

    I di N t k f P ti t C

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    Indiana Network for Patient Care

    HL7 v2.x Message

    I di N t k f P ti t C

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    Indiana Network for Patient Care

    HL7 v2.x Message

    I di N t k f P ti t C

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    Indiana Network for Patient Care

    HL7 v2.x Message

    I di N t k f P ti t C

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    Indiana Network for Patient Care

    HL7 v2.x Message

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    Result with a Coded Value

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    Result with a Coded Value

    Data type of result

    (OBX-5) is a coded

    element

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    Result with a Coded Value

    Data type of result

    (OBX-5) is a coded

    element

    This code is

    from LOINC

    Code identifying this

    observation

    (what are these results?

    Conditions identified by

    newborn screening )

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    Result with a Coded Value

    Data type of result

    (OBX-5) is a coded

    element

    This code is

    from LOINC

    Code identifying this

    observation

    (what are these results?

    Conditions identified by

    newborn screening )

    This code is from

    SNOMED

    Code identifying the result

    (Phenylketonuria )

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    photo via eye of einstein

    http://www.flickr.com/photos/35188692@N00/466404658/sizes/o/in/photostream/http://www.flickr.com/photos/35188692@N00/466404658/sizes/o/in/photostream/http://www.flickr.com/photos/35188692@N00/466404658/sizes/o/in/photostream/http://www.flickr.com/photos/35188692@N00/466404658/sizes/o/in/photostream/http://www.flickr.com/photos/35188692@N00/466404658/sizes/o/in/photostream/
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    LOINC(noun)

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    LOINC(noun)o LOINC, LOINCing, LOINCed (verb)

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    LOINC(noun)o LOINC, LOINCing, LOINCed (verb)

    [Chief, Head, etc] LOINCer(noun)

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    LOINC(noun)o LOINC, LOINCing, LOINCed (verb)

    [Chief, Head, etc] LOINCer(noun)

    LOINCification (noun)

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    LOINC(noun)o LOINC, LOINCing, LOINCed (verb)

    [Chief, Head, etc] LOINCer(noun)

    LOINCification (noun)

    From Standardizing the MDS with LOINC and Vocabulary Matcheshttp://aspe.hhs.gov/daltcp/reports/2007/MDS-LOINC.htm

    http://aspe.hhs.gov/daltcp/reports/2007/MDS-LOINC.htmhttp://aspe.hhs.gov/daltcp/reports/2007/MDS-LOINC.htmhttp://aspe.hhs.gov/daltcp/reports/2007/MDS-LOINC.htmhttp://aspe.hhs.gov/daltcp/reports/2007/MDS-LOINC.htm
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    LOINC(noun)o LOINC, LOINCing, LOINCed (verb)

    [Chief, Head, etc] LOINCer(noun)

    LOINCification (noun)

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    LOINC(noun)o LOINC, LOINCing, LOINCed (verb)

    [Chief, Head, etc] LOINCer(noun)

    LOINCification (noun)

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    LOINC(noun)o LOINC, LOINCing, LOINCed (verb)

    [Chief, Head, etc] LOINCer(noun)

    LOINCification (noun)

    SNOMED (noun)

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    LOINC(noun)o LOINC, LOINCing, LOINCed (verb)

    [Chief, Head, etc] LOINCer(noun)

    LOINCification (noun)

    SNOMED (noun)

    SNOMEDicated???

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    LOINC(noun)o LOINC, LOINCing, LOINCed (verb)

    [Chief, Head, etc] LOINCer(noun)

    LOINCification (noun)

    SNOMED (noun)

    SNOMEDicated???

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    Different standards for differentparts of the elephant.

    photo via Ludovic Hirlimann

    http://www.flickr.com/photos/lhirlimann/http://www.flickr.com/photos/lhirlimann/http://www.flickr.com/photos/lhirlimann/http://www.flickr.com/photos/lhirlimann/http://www.flickr.com/photos/lhirlimann/http://www.flickr.com/photos/lhirlimann/http://www.flickr.com/photos/lhirlimann/
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    photo via x-ray delta one

    Laboratory LOINC

    http://www.flickr.com/photos/x-ray_delta_onehttp://www.flickr.com/photos/x-ray_delta_onehttp://www.flickr.com/photos/x-ray_delta_one
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    Laboratory LOINC

    Clinical LOINC

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    Clinical LOINC

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    photo via LuzA

    Standardized Assessments and Collections

    http://www.flickr.com/photos/luchilu/http://www.flickr.com/photos/luchilu/
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    Vreeman DJ, McDonald CJ, Huff SM. Representing patient assessments in LOINC. AMIA Annu Symp Proc. 2010;832-836. PMID: 21347095 .

    Vreeman DJ, McDonald CJ, Huff SM. LOINC - A Universal Catalog of Individual Clinical Observations and Uniform Representation of Enumerated Collections. Int J Funct InformPersonal Med. 2010;3(4):273-291.

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    Laboratory LOINC Committee Chair:

    Clem McDonald, MD

    Clinical LOINC Committee Chair:

    Stan Huff, MD

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    Open Development

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    Open Development

    Worldwide distribution at no costNew terms from end-users

    Welcome all comersCommittees are volunteers

    Open Development

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    Open Development

    Worldwide distribution at no costNew terms from end-users

    Welcome all comersCommittees are volunteers

    Open Development

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    Open Development

    Worldwide distribution at no costNew terms from end-users

    Welcome all comersCommittees are volunteers

    Its free, but invaluable

    R i f I i

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    Regenstrief Institute

    StewardDeveloper of content

    Developer of toolsDeveloper of community

    DistributorVoice

    F di S

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    Funding Support

    Main current sources are:U.S. National Library of Medicine

    Regenstrief Foundation

    Prior support from

    Several other U.S. federal agencies,John A. Hartford Foundation

    LOINC Codes Over Time by Release

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    0!10,000!20,000!30,000!40,000!50,000!60,000!70,000!80,000!

    4/2

    4/19

    95|1

    .0!

    5/24

    /199

    5|1

    .0a!

    6/23

    /199

    5|1

    .0b!

    6/28

    /199

    5|1

    .0c!

    7/14

    /199

    5|1

    .0d!

    9/15

    /199

    5|1

    .0e!

    12/21

    /199

    5|1

    .0f!

    4/28

    /199

    6|1

    .0g!

    8/29/19

    96|1

    .0h(

    2)!

    12/3/19

    96|1

    .0h(

    3)!

    1/8/

    1999

    7|1

    .0i!

    10/9/

    1997

    |1.0j-a

    !

    5/1

    /199

    8|1

    .0k!

    2/12

    /199

    9|1

    .0l!

    7/23/

    1999

    |1.0

    m!

    8/6

    /199

    9|1

    .0m

    a!

    2/4

    /200

    0|1

    .0n!

    6/13

    /200

    0|1

    .00!

    1/1

    /200

    1|2

    .00!

    1/31

    /200

    1|2

    .01!

    7/1

    /200

    1|2

    .03!

    1/1

    /200

    2|2

    .04!

    2/1

    /200

    2|2

    .05!

    2/19

    /200

    2|2

    .06!

    8/1

    /200

    2|2

    .07!

    9/1

    /200

    2|2

    .08!

    5/1

    /200

    3|2

    .09!

    10/1

    /200

    3|2

    .10!

    1/1

    /200

    4|2

    .11!

    2/1

    /200

    4|2

    .12!

    12/1

    /200

    4|2

    .13!

    12/1

    /200

    4|2

    .14!

    6/1

    /200

    5|2

    .15!

    12/1

    /200

    5|2

    .16!

    6/1

    /200

    6|2

    .17!

    12/2

    1/20

    06|2

    .19!

    6/2

    1/20

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    .21!

    12/0

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    07|2

    .22!

    7/1

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    08|2

    .24!

    1/1

    0/20

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    .26!

    07/0

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    12/3

    0/20

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    .29!

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    .30!

    6/1

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    .36!

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    .38!

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    0/20

    12|2

    .40!

    LOINC Codes!Lab Codes!

    y

    laboratory terms only

    LOINC Codes Over Time by Release

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    0!10,000!20,000!30,000!40,000!50,000!60,000!70,000!80,000!

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    .0!

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    /199

    5|1

    .0a!

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    /199

    5|1

    .0b!

    6/28

    /199

    5|1

    .0c!

    7/14

    /199

    5|1

    .0d!

    9/15

    /199

    5|1

    .0e!

    12/21

    /199

    5|1

    .0f!

    4/28

    /199

    6|1

    .0g!

    8/29/1

    996

    |1.0h(

    2)!

    12/3/1

    996

    |1.0h(

    3)!

    1/8/

    1999

    7|1

    .0i!

    10/9/

    1997

    |1.0j-a

    !

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    8|1

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    9|1

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    1999

    |1.0

    m!

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    2/1

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    /200

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    /200

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    /200

    6|2

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    12/2

    1/20

    06|2

    .19!

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    3/20

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    .40!

    LOINC Codes!Lab Codes!

    y

    Slope = 600

    laboratory terms only

    LOINC Codes Over Time by Release

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    0!10,000!20,000!30,000!40,000!50,000!60,000!70,000!80,000!

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    4/19

    95|1

    .0!

    5/24

    /199

    5|1

    .0a!

    6/23

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    5|1

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    /199

    5|1

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    /199

    5|1

    .0d!

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    /199

    5|1

    .0e!

    12/21

    /199

    5|1

    .0f!

    4/28

    /199

    6|1

    .0g!

    8/29/1

    996

    |1.0h(

    2)!

    12/3/1

    996

    |1.0h(

    3)!

    1/8

    /199

    97|1

    .0i!

    10/9/

    1997

    |1.0j-a

    !

    5/1

    /199

    8|1

    .0k!

    2/1

    2/19

    99|1

    .0l!

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    99|1

    .0m

    !

    8/6

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    9|1

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    a!

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    .27!

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    0/20

    09|2

    .29!

    2/2

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    .30!

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    .36!

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    .38!

    6/3

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    .40!

    LOINC Codes!Lab Codes!

    y

    Slope = 600

    Slope = 2200

    laboratory terms only

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    http://www.flickr.com/photos/liberhttp://www.flickr.com/photos/liber
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    19,600+ users in 149 countries

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    19,600 users in 149 countries

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    0

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    17 new members per day520 new members per month

    loinc.org members

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    17 new members per day520 new members per month

    Doubled in 19 months!

    loinc.org members

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    17 new members per day520 new members per month

    Mental Tipping Point -Oh Snap!

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    search.loinc.org

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    Alternate Language Search

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    Alternate Language Search

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    Everything in Italian!

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    photo via 917press

    http://www.flickr.com/photos/917press/http://www.flickr.com/photos/917press/http://www.flickr.com/photos/917press/
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    Just kidding.

    Copyright is agoodthing for

    standards.

    Its the licensing part that isinteresting.

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    No cost

    Worldwide

    In perpetuity

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    Use

    Copy

    Distribute

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    Any purpose:

    commercial

    non-commercialphoto via Refracted Moments

    http://www.flickr.com/photos/refractedmoments/http://www.flickr.com/photos/refractedmoments/http://www.flickr.com/photos/refractedmoments/
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    CANNOT use anyLicensed Material to

    develop or promulgate adifferent standard for

    orders or observations.

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    That would defeat

    the purpose of

    having a standard!

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    LOINC Submitters

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    105 i ti f 15 t i

    Since 2009:

    LOINC Translators22 organizations

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    22 organizations

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    Vreeman DJ et al. Enabling international adoption of LOINC through translation. J Biomed Inform (2012), doi:10.1016/j.jbi.2012.01.005

    http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005
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    Vreeman DJ et al. Enabling international adoption of LOINC through translation. J Biomed Inform (2012), doi:10.1016/j.jbi.2012.01.005

    1

    st International

    http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005
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    Vreeman DJ et al. Enabling international adoption of LOINC through translation. J Biomed Inform (2012), doi:10.1016/j.jbi.2012.01.005

    1 International

    LOINC PhD student

    http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005http://dx.doi.org/10.1016/j.jbi.2012.01.005
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    Adopted as National Standard

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    p

    AustraliaBrazil

    Canada

    CyprusEstonia

    France

    Germany

    MexicoMongolia

    The Netherlands

    RwandaThailand

    Turkey

    United States

    Large Implementations

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    g p

    SIGA Sade projectCanada Health Infoway

    ePSOS

    Assistance publique - Hpitaux de Paris

    BiTAC

    Hong Kong Hospital Authority

    Philippine Health Insurance Corporation

    Many more...

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    For the last few years, the AP-HP has

    been using the LOINC internationalnomenclature

    Thanks to this catalogue, the AP-HP isable to use the nomenclature in itstreatment processes, whenever

    biology analyses and test results arerequested.

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    Members of the Korean National StandardsCommittee have enthusiastically embraced LOINC

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    Some serious LOINCing in Hong Kong

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    S t i LOINCi

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    Talking about LOINC at the Thai Ministry of

    I f ti d C i ti T h l y

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    D C l di LOINCi i Cy

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    This agreement further solidifiesthe wonderful relationship HL7has enjoyed with Regenstrief for

    many years.

    - Bob Dolin, MDChair of HL7 Board of Directors

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    US AdoptionA few key highlights

    Some Key US Adoptions

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    All the big labsAll health-related federal agencies

    Lots of care organizations

    HIEs

    Insurance companies

    EHR vendorsInstrument manufacturers (nascent)

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    CMS EHR Incentive

    Programa.k.a. Meaningful Use

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    vsac.nlm.nih.gov

    https://vsac.nlm.nih.gov/https://vsac.nlm.nih.gov/
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    photo via IMLS DCC

    http://www.flickr.com/photos/imlsdcc/5637868432/sizes/o/in/photostream/http://www.flickr.com/photos/imlsdcc/5637868432/sizes/o/in/photostream/http://www.flickr.com/photos/imlsdcc/5637868432/sizes/o/in/photostream/
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    If Murky, Dont Assume

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    Units of measure are critical.

    Sample results can help identify thecorrect LOINC Scale.

    Local experts, package inserts can bevery informative.

    Clean water act

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    photo via Fishking_1

    Upstream standardization.

    Ask instrument or test kitmanufacturers.

    ivdconnectivity.org

    http://www.flickr.com/photos/fishking1/5304638016/sizes/o/in/photostream/http://www.flickr.com/photos/fishking1/5304638016/sizes/o/in/photostream/http://www.flickr.com/photos/fishking1/5304638016/sizes/o/in/photostream/
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    A journey.

    Not a destination.

    Ongoing Journey

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    Plan for updating as yourtesting

    changes(less common), or your localcode identifiers change (more common).

    Ongoing Journey

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    Replace mappings to deprecated

    terms with new LOINC releases.

    (RELMA can help)

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    Prioritization

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    Local or national policies may helpprioritize mapping subsets.

    For example:

    common results

    + panel elements

    + public health reportable tests

    Jump In!

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    photo via Justin Ornellas

    http://www.flickr.com/photos/ornellas/http://www.flickr.com/photos/ornellas/http://www.flickr.com/photos/ornellas/http://www.flickr.com/photos/ornellas/
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    photo via ryarwood

    http://www.flickr.com/photos/yarwood/http://www.flickr.com/photos/yarwood/
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    photo via milos milosevic

    LOINC Downloads

    1800

    2000

    http://www.flickr.com/photos/21496790@N06/http://www.flickr.com/photos/21496790@N06/http://www.flickr.com/photos/21496790@N06/http://www.flickr.com/photos/21496790@N06/http://www.flickr.com/photos/21496790@N06/
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    400

    600

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    1200

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    1800