2003-2004 GIHB Pharmacology Review 19 September 2015 3:29 AM.
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Transcript of 2003-2004 GIHB Pharmacology Review 19 September 2015 3:29 AM.
2003-2004GIHB Pharmacology
Review
April 19, 202305:33 PM
Activated charcoal
Antidote
Albendazole
Antihelminthic
Treatment of intestinal roundworms
Alosetron
IBS treatment
5HT3 receptor antagonist
Aluminum hydroxide
Antiulcer
Antacid
Amoxicillin
Penicillin antibioticCell wall synthesis inhibitor
Antiulcer
Amino penicillinInhibits peptidoglycan cross-
linking
Ampicillin
Penicillin antibioticCell wall synthesis inhibitor
Amino penicillinInhibits peptidoglycan cross-
linking
Anthraquinonescascara segrada, danthron, senna
Contact cathartics
Aprepitant dimenhydrinate
Antiemetic
Neurokinin 1 receptor antagonist
Arsenicals
Tropical antiparasitic
Treatment of African Trypanosomiasis in CNS
Melarsoprol
Atropine
Anticholinergic
AntimuscarinicTreatment for bradycardia,
diarrhea, cholinesterase poisoning
Azithromycin
Macrolide antibioticBacteriostatic protein synthesis
inhibitor
50S ribosome Inhibits translocation
Balsalazide
NSAID (salicylate)
Treatment of IBD
Bisacodyl
Contact cathartic
Bismuth subsalicylate
AntiulcerAntidiarrheal
Budesonide
AdrenocorticosteroidGlucocorticoid
Anti-inflammatory steroidInhaled OR treatment of IBD
Calcium carbonate
Antiulcer
Antacid
Cascara sagrada
Contact cathartic
Anthraquinone derivative
Castor Oil
Contact cathartic
Cimetidine
AntihistamineAntiulcer
H2 receptor antagonist
Cisapride
Prokinetic agent
5HT4 agonist
Clarithromycin
Macrolide antibioticBacteriostatic protein synthesis
inhibitor Antiulcer
50S ribosomeInhibits translocation
Danthron
Contact cathartic
Anthraquinone derivative
Dexamethasone
AdrenocorticosteroidGlucocorticoidAntineoplastic
Antiemetic
Anti-inflammatory steroidNot by inhalation
Diethylcarbamazine
Antihelminthic
Treatment of intestinaland tissue roundworms
Dimenhydrinate
AntihistamineAntiemetic
H1 receptor antagonist
Diphenhydramine
Classical antihistamineAntiemetic
H1 antagonist
Diphenoxylate docusate
Antidiarrheal
Opiate
Docusates
Lubricating laxatives
Stool softeners
Doxycycline
Tetracycline antibioticBacteriostatic protein synthesis
inhibitor
30S ribosomePrevents aminoacyl tRNA attachment
Dronabinol
Antiemetic
Cannabinoid
Droperidol
Antiemetic
D2 receptor antagonist
Erythromycin
Macrolide antibioticBacteriostatic protein synthesis
inhibitor
50S ribosomeInhibits translocation
Granisetron
Antiemetic
5HT3 receptor antagonist
Infliximab
TNF inhibitor
Anti-TNF monoclonal antibody Treatment of IBD
Iodoquinol
Antiparasitic
Treatment of protozoal infections
Ipecac
Emetic
Ivermectin
Antihelminthic
Treatment of intestinaland tissue roundworms
Kaolin
Antidiarrheal
Lactulose
Saline (osmotic) cathartic
Lansoprazole
Antiulcer
H+/K+ ATPase inhibitor
Loperamide
Antidiarrheal
Opiate
Magnesium hydroxide
AntiulcerSaline (osmotic) cathartic
Antacid
Mebendazole
Antihelminthic
Treatment of intestinal roundworms
Meclizine
AntihistamineAntiemetic
H1 receptor antagonist
Meglumine antimonate
Tropical antiparasitic
Organic antimonialTreatment of Leishmaniasis
Melarsoprol
Tropical antiparasitic
Treatment of African Trypanosomiasis in CNS
Mesalamine(5-ASA)
NSAID (salicylate)
Treatment of IBD
Methylcellulose
Bulk laxative
Metoclopramide
Prokinetic agentAntiemetic
D2 antagonist
Metronidazole
AntibioticAntiparasitic
Antiulcer
AnaerobesReduction leads to intermediates
that damage DNA
Mineral oil
Lubricating laxative
Stool softener
Minocycline
Tetracycline antibioticBacteriostatic protein synthesis
inhibitor
30S ribosomePrevents aminoacyl tRNA attachment
Misoprostol
ProstaglandinAntiulcer
Nifurtimox
Tropical antiparasitic
Treatment of South American Trypanosomiasis; Chagas
disease
Olsalazine
NSAID (salicylate)
Treatment of IBD
Omeprazole/esomeprazole
Antiulcer
H+/K+ ATPase inhibitor
Ondansetron
Antiemetic
5HT3 receptor antagonist
Organic antimonials
Tropical antiparasitic
Treatment of Leishmaniasis
sodium stibogluconatemeglumine antimonate
Oxytetracycline
Tetracycline antibioticBacteriostatic protein synthesis
inhibitor
30S ribosomePrevents aminoacyl tRNA attachment
Pantoprazole
Antiulcer
H+/K+ ATPase inhibitor
Paromomycin
AntiparasiticAminoglycoside antibiotic
Treatment of protozoal infections
Pectin
Antidiarrheal
Pentamidine
Tropical antiparasitic
Treatment of African Trypanosomiasis
Polyethylene glycol- electolyte solution
AntidoteCathartic
Praziquantel
Antihelminthic
Treatment of trematode (fluke) and cestode (tapeworm)
infections
Procarbazine
Antineoplastic
MiscellaneousProbably acts as alkylating
agent
Prochlorperazine
Antiemetic
D2 receptor antagonistPhenothiazine
Promethazine
Classical antihistamineAntipsychotic
Antiemetic
H1 antagonist
Pyrantel Pamoate
Antihelminthic
Treatment of intestinal roundworms
Pyrimethamine
AntimalarialProtein and nucleic acid
synthesis inhibitor
Plasmodial dihydrofolate reductase inhibitor
Rabeprazole
Antiulcer
H+/K+ ATPase inhibitor
Ranitidine
AntihistamineAntiulcer
H2 receptor antagonist
Rebamipide
Antiulcer
Senna
Contact cathartic
Anthraquinone derivative
Scopolamine
AnticholinergicAntiemetic
Muscarinic receptor antagonist
Simethicone
Anti-flatulent
Sodium bicarbonate
AntiulcerAntidote
AntacidAlkalinization of urine to treat drug toxicity (esp. barbiturates, salicylates,
methanol)
Sodium phosphate
Saline (osmotic) cathartic
Sodium stibogluconate
Tropical antiparasitic
Organic antimonial Treatment of Leishmaniasis
Sucralfate
Antiulcer
Sulfasalazine
Disease modifyinganti-rheumatic drug (DMARD)
Metabolized to sulfonamide+ salicylate (NSAID) Treatment of IBD
Suramin
Tropical antiparasitic
Treatment of African Trypanosomiasis
Tegaserod
IBS treatment
5HT4 receptor agonist
Tetracycline
AntibioticBacteriostatic protein synthesis
inhibitor Antiulcer
30S ribosomePrevents aminoacyl tRNA attachment
Thiabendazole
Antihelminthic
Treatment of intestinal roundworms