2,000,000 - U S Food and Drug Administration Home Page · antibiotics are becoming more ......
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THE PROBLEM 88 YEARS Antimicrobial drugs have been widely used in human and veterinary medicine, with tremendous benefits. Antimicrobial drug use in humans and animals has led to increased resistance. Illnesses that were once easily treatable with antibiotics are becoming more difficult to cure and more expensive to treat. HOPE FOR THE FUTURE NARMS tracks resistance in intestinal bacteria from retail meats, people, and food- producing animals. This information is used to combat antibiotic resistance through regulations, policies and public health interventions promoting antibiotic stewardship. Established in 1996, NARMS is a collaboration among the U.S. Food and Drug Administration, Centers for Disease Control and Prevention, and the U.S. Department of Agriculture, and state and local health departments to monitor antibiotic resistance in bacteria that are found in retail meats, humans, and food-producing animals. NARMS is a national public health surveillance program that monitors antibiotic resistance in drugs critically important to human medicine. To accomplish its mission, NARMS conducts the following activities: What does NARMS do? Disseminates timely information on antimicrobial resistance to promote interventions that reduce resistance among foodborne bacteria. Conducts research to better understand the emergence, persistence, and spread of antimicrobial resistance. Monitors trends in antimicrobial resistance within foodborne bacteria from humans, retail meats, and food producing animals. THE 3 ARMS OF NARMS Retail Meats - The retail meat component of NARMS laboratories in 18 states purchases retail meats and culture them for the target bacteria. Isolates are sent to FDA's Center for Veterinary Medicine for species and serotype confirmation, antimicrobial susceptibility testing, and genetic analysis. Humans - CDC conducts nationwide surveillance of foodborne bacteria from human isolates. Antimicrobial susceptibility testing is conducted at the National Center for Emerging and Zoonotic Infectious Diseases. USDA Animals - USDA collects samples from food- producing animals at slaughter in a way that is representative of national production. USDA also tests Hazard Analysis and Critical Control Points (HACCP) isolates of Salmonella collected by USDA in its oversight role to ensure hygienic practices in processing plants. CDC FDA DATA FOR MAKING DECISIONS Antimicrobial resistance data from humans and food-producing animals are important for the development of public health recommendations for the use of drugs in humans and food animals, with the goal of preserving the effectiveness of these important drugs for the future. 2,000,000 People in the United States become infected with bacteria that are resistant to antibiotics, according to CDC's 2013 Threat Report. COMBATING RESISTANCE WITH SURVEILLANCE Documents resistance levels in different sources Generates hypotheses about sources of resistant bacteria Describes the spread of resistant bacterial strains and resistance genes Data provides insight on current and emerging hazards Guides sound scientifically-based policies and guidelines to make the best use of antimicrobials in hospitals, communities, agriculture, aquaculture, and veterinary medicine BASELINE DATA SPREAD ATTRIBUTION EDUCATION POLICY THE RESULTS.... NARMS produces annual summary reports on antimicrobial resistance among bacteria isolated from humans, retail meats, and food animals. NARMS also publishes integrated survey reports that consolidate data from all sources into an interactive format. ANNUAL SUMMARY REPORTS INTEGRATED SURVEILLANCE REPORTS Since 2009, these reports have also included a summary describing the most important data points; and they also include interactive graphs of antimicrobial resistance among Salmonella and Campylobacter. TIP NARMS NOW is an interactive tool that allows anyone to download and analyze isolate-level data for over 155,000 isolates in different formats. Incorporated whole genome sequencing into surveillance, making it possible to more rapidly and accurately detect the presence of antimicrobial resistant bacteria. NARMS is positioned to help measure the impact of FDA policy stopping the use of antibiotics for growth promotion. Contributed to the scientific understanding of foodborne disease through research based on NARMS findings. FROM DATA TO ACTION Learn more at:
Transcript of 2,000,000 - U S Food and Drug Administration Home Page · antibiotics are becoming more ......
THEPROBLEM88 YEARS
Antimicrobial drugs havebeen widely used in
human and veterinarymedicine, with
tremendous benefits.
Antimicrobial drug use in humansand animals has led to increased
resistance. Illnesses that wereonce easily treatable with
antibiotics are becoming moredifficult to cure and more
expensive to treat.
HOPE FOR THEFUTURE
NARMS tracks resistance inintestinal bacteria from retail
meats, people, and food-producing animals. This
information is used to combatantibiotic resistance through
regulations, policies and publichealth interventions promoting
antibiotic stewardship.
Established in 1996, NARMS is a collaboration among the U.S. Foodand Drug Administration, Centers for Disease Control and Prevention,
and the U.S. Department of Agriculture, and state and local healthdepartments to monitor antibiotic resistance in bacteria that are
found in retail meats, humans, and food-producing animals.
NARMS is a national public health surveillance program that monitorsantibiotic resistance in drugs critically important to human medicine.
To accomplish its mission, NARMS conducts the following activities:
What does NARMS do?
Disseminates timely information on antimicrobial resistance to promote interventions that reduce resistance among foodborne bacteria.
Conducts research to better understand the emergence, persistence,and spread of antimicrobial resistance.
Monitors trends in antimicrobial resistance within foodborne bacteriafrom humans, retail meats, and food producing animals.
THE 3 ARMS OF NARMSRetail Meats - The retail meat component of NARMSlaboratories in 18 states purchases retail meatsand culture them for the target bacteria.
Isolates are sent to FDA's Center for VeterinaryMedicine for species and serotype confirmation,antimicrobial susceptibility testing, and geneticanalysis.
Humans - CDC conducts nationwide surveillanceof foodborne bacteria from human isolates.
Antimicrobial susceptibility testing is conductedat the National Center for Emerging and ZoonoticInfectious Diseases.
USDAAnimals - USDA collects samples from food-producing animals at slaughter in a way that isrepresentative of national production. USDA alsotests Hazard Analysis and Critical Control Points(HACCP) isolates of Salmonella collected by USDAin its oversight role to ensure hygienic practices inprocessing plants.
CDCFDA
DATA FOR MAKING DECISIONS
Antimicrobial resistance data from humans and food-producinganimals are important for the development of public healthrecommendations for the use of drugs in humans and food animals,with the goal of preserving the effectiveness of these important drugsfor the future.
2,000,000People in the United States become infectedwith bacteria that are resistant to antibiotics,
according to CDC's 2013 Threat Report.
COMBATING RESISTANCE WITH SURVEILLANCE
Documents resistance levels indifferent sources
Generates hypotheses about sources ofresistant bacteria
Describes the spread of resistantbacterial strains and resistance genes
Data provides insight on current andemerging hazards
Guides sound scientifically-basedpolicies and guidelines to make thebest use of antimicrobials in hospitals,communities, agriculture, aquaculture,and veterinary medicine
BASELINE DATA
SPREAD
ATTRIBUTION
EDUCATION
POLICY
THE RESULTS....
NARMS produces annual summary reports onantimicrobial resistance among bacteria isolatedfrom humans, retail meats, and food animals.
NARMS also publishes integrated surveyreports that consolidate data from all sources intoan interactive format.
ANNUALSUMMARYREPORTS
INTEGRATEDSURVEILLANCEREPORTS
Since 2009, these reports have also included a summary describing themost important data points; and they also include interactive graphs of
antimicrobial resistance among Salmonella and Campylobacter.
TIP NARMS NOW is an interactive tool that allows anyone to download andanalyze isolate-level data for over 155,000 isolates in different formats.
Incorporated whole genome sequencing into surveillance, making itpossible to more rapidly and accurately detect the presence ofantimicrobial resistant bacteria.
NARMS is positioned to help measure the impact of FDA policy stoppingthe use of antibiotics for growth promotion.
Contributed to the scientific understanding of foodborne disease throughresearch based on NARMS findings.
FROM DATA TO ACTION
Learn more at:
