1.900 new children affected each day by AIDS , that is 1 child every 20 seconds
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Transcript of 1.900 new children affected each day by AIDS , that is 1 child every 20 seconds
1.900 new children affected each day by AIDS, that is 1 child every 20 seconds
dedicated to Global solidarity
20% deaths among children in Africa due to malaria,
a disease which can be cured…
Near 2 billion people affected by tuberculosis, that is one third of the world population
UNITAID sets up programs for HIV / AIDSmalariatuberculosis
A Global State of Emergency…
Medicines are in the North, patients in the South
The less developed countries represent:
84% of the world population
less than11% of the global health expenditure
more than 93% of the global disease burden
2.1 million HIV positive children in the world
660,000 children need ARV Only 40,000 benefit from it
Drug resistance is increasing Only 8% of pregnant women get ARV to prevent transmission of the disease to their baby
1st cause of child mortality for a disease that can be cured The disease burden is growing
ACTs are the most efficient treatment against growing drug resistances (efficient for 95% cases)
2 million people die from tuberculosis each year
1st cause of mortality for people with Aids
Drug resistance is growing Multi drug resistant treatments are extremely expensive (4.000 $/year)
Official signature of the five founder countries when UNITAID was launched, on 19 September 2006, United Nations, New York
27 donor countries already joined UNITAID
Guinea has just joined on 30th August 2007
Countries that implemented the air tickets levy
Tax already in place or now been implemented:
- France- Chile- Norway (tax on CO2 from airplanes)- Côte d’Ivoire- Congo - Guinea Conakry - South Korea- Madagascar - Mauritius - Namibia- Niger
Countries which have committed to implement the tax: Benin, Burkina Faso, Cameroon, Gabon, Liberia, Mali, Morocco, Central African Republic, Senegal,Sao Tome & Principe, Togo
UNITAID EXPECTED REVENUES 2006-2009
2007 2008 2009
Brazil 10,000 10,000 10,000Chile (1) 6,049 3,500 3,500France (1) 212,598 215,054 215,054Norway (1) 21,625 22,000 22,000UK 26,490 40,323 69,893
Spain 20,161 20,000 20,000New donors* (1) 10,000 80,000 150,000
------------- ------------- -------------318,023 390,876 490,446
% of airtickets levy or alike 84% 90% 90%
(1) airtickets levy or alike (CO2)
( '000 $ US)
* includes Korea (15 M$) Cote d’Ivoire, Congo, Madagascar, Mauritius, Guinea Conakry and Niger (tax already adopted) and 17 other countries where the tax is being implemented
The Gates foundation will also bring 10 M$ per year
More than 80% of UNITAID revenue is based on the air ticket levy
Impact of the air tickets levy: an example
Tax received on each ticket by
UNITAID (in France)
Economy classFirst class or
business
Flight in France or in
Europe
1 € 10 €
International flight
4 € 40 €
An aircraft with 300 passengers on board leaving from Paris will cover the treatment for 1 person with multi drug resistant tuberculosis, which is very expensive (approx. 4.000 $)
Antimalarial treatment for 2 children
1 HIV-positive childunder treatment
for 1 year
ex: flight Paris - Berlin
ex: flight Paris - Dakar
Furthermore… no economic impact on air traffic
1/ Improve access to treatment for HIV/AIDS, TB, malaria in developing countries
2/ Get lower prices for quality drugs and diagnostics
3/ Speed up products availability
Predictable long-term funding A budget over $ 300 million in 2007, 90% being already committed Price reductions as a result of larger volumes (pool procurement) 85% of funds for the poorest countries A small secretariat hosted by WHO: no bureaucracy
UNITAID objectives
UNITAID use of funds allows to:
1/ have manufactured drugs better adapted to patient needs (fix dose combinations)
2/ reduce prices: more drugs available for the same budget
3/ contribute to a better quality (pre qualification of drugs, incentive for manufacturers to invest)
4/ rapidly deliver drugs in the countries in need
UNITAID added value
UNITAID uses a wide range of tools to help reduce prices and accelerateavailability of drugs
Pool procurement
Prequalification
COST plus pricingPredictable funding
Encouraging market competition
Lowering barriers to entry on market
Market dynamics forecastVolume price negotiation
Partnership pricing
Encouraging technology sharing
Supporting local registration
Encouraging/attracting new manufacturers
Information sharing
Reference price / price ceiling
UNITAID works together with well-recognized partners :
A unique partnership model
In the last months, UNITAID
has committed to funding projects
against the three diseases…
I/ Pediatric ARV: Have 100,000 new HIV-positive children under adapted ARV treatments in 2007 (today only 40,000 are covered when 660,000 need it) in 40 countries.
II/ 2nd line ARV: reduce prices for 7 products and provide treatments for 60,000 new patients in 27 countries in 2007.
III/ Prevention of mother to child transmission: improve the care, reduce diagnostic prices, have 1.2 million pregnant women tested and 340,000 under ARV treatment in 8 countries in 2007-2008.
Ongoing UNITAID programsHIV / AIDS
Partner: the Clinton Foundation
Partners: WHO and UNICEF
53 recipient countries from UNITAID fundsagainst HIV / AIDS
AFROAngolaBenin
BotswanaBurkina Faso
BurundiCameroon
ChadDRC
Cote d'IvoireEthiopiaGhanaGuineaKenya
LesothoLiberiaMalawi
MaliMozambique
NamibiaNigeriaRwandaSenegal
South AfricaSwazilandTanzania
TogoUgandaZambia
Zimbabwe
SEAROIndia
Thailand
WPROCambodia
ChinaLao
Papua New GuineaVietnam
AMRODominican Rep.
GuyanaHaiti
JamaicaOECS
(Anguilla, Dominica, St Lucia,
Antigua & Barbuda, Grenada,
St Christopher & Nevis, British Virgin Islands,
Montserrat, St Vincent & Grenadines)
EUROMoldovaSerbia
EMRODjiboutiMoroccoTunisia
I/ ACT scale up: Scale up ACT treatments in eleven countries, until 2010, for 55 million treatments, in order to have an impact on prices, give an incentive to manufacturers, avoid stock out in countries.
II/ ACT program in Liberia and Burundi : Provide nearly 1.3 million treatments in these two countries that had no coverage for 2007, before other donors stepped in.
Ongoing UNITAID programsMalaria
Partners: The Global Fund and UNICEF
Partners: WHO and UNICEF
22 recipient countries from UNITAID fundsagainst malaria
AFROBurundi
Cote d'IvoireEritrea
EthiopiaGambiaGhanaGuinea
Guinea BissauLiberia
MadagascarMali
MauritaniaMozambique
NamibiaSomaliaZambia
EMRODjiboutiSudan
SEAROBangladeshIndonesia
WPROCambodia
China
I/ 1st line TB : Support the transitional provision of 740,000 treatments in 2007-2008 for 18 countries and establish a strategic rotating stockpile.
II/ Pediatric TB: provide treatments adapted to children in order to treat
150,000 children by the end of 2007.
III/ Multi drug resistant TB : Support the purchase of 4,700 treatments
in 2007 for 17 low income and lower middle income countries, with a
view to decreasing prices.
Partner: The Global Drug Facility
Partners: The Global Drug Facility and the Global Fund
Partners: WHO and UNICEF
Ongoing UNITAID programsTuberculosis
58 recipient countries from UNITAID fundsagainst tuberculosis
AFROBenin
Burkina FasoCape VerdeCameroon
Congo BrazzavilleDRC
Cote d'IvoireThe Gambia
GuineaKenya
LesothoMadagascar
MalawiMali
MauritaniaMozambique
NigerNigeriaRwandaSomaliaTanzania
TogoUgandaZambia
SEAROBangladesh
BhutanIndia
IndonesiaMyanmar
NepalSri Lanka
Timor-Leste
EUROAzerbaijan
Bosnia-HerzegovinaBelarusBulgariaGeorgia
KyrgyzstanKazakhstan
MoldovaTajikistan
Uzbekistan
EMROAfghanistan
DjiboutiEgyptIraq
LebanonPakistan
Syrian Arab Rep.Yemen
WPROCambodia
LaoPhilippines
Vietnam
AMRODominican Rep.
Guatemala Haiti
Facing a global state of emergency, UNITAID contributes to bring solutions
In less than a year, UNITAID has
already achieved major results…
1/ First significant price reductions
30 November 2006 on antiretroviral
for HIV positive children(with the Clinton foundation)
8 May 2007 on second-lineantiretroviral
(with the Clinton foundation)-27%
-23%
-32%-40
-30
-20
-10
0
10
20
30
ABACAVIR 300mg TENOFOVIR 300 mg TENOFOVIR 300mg/ LAMIVUDINE300mg
-39%
-57%
-26%-29%
-33%-29%
-60
-50
-40
-30
-20
-10
0
10
20
30
40
TDF TDF+3TC TDF+FTC ddl ABC LPV/r
"My long experience in public policy taught me that even those who don't like taxes are not reluctant to pay a contribution for a good
cause.
Thanks to UNITAID, we succeeded to lower the annual cost of a treatment for a child
with AIDS from 196 $ to 60 $. Each citizen who gets into an plane and pays its
contribution should reflects on that : with the same amount of money, we save three time
more children.."
President Bill Clinton Le Monde – 25th July 2007
UNITAID first results
2/ More user-friendly drugs
With UNITAID funding, new treatments put on the market against HIV/AIDS are more adapted :
- Doses well adapted to children corpulence
- Drugs to be taken in the form of tablets (fix dose combination) : 1 tablet replaces several doses daily
- Heat stable drugs : no refrigeration needed anymore
- No need to dilute them in water (problem of access to drinkable water in some countries).
Pediatric DFC make easier HIV/AIDS treatment, for patients but also for healthcare professionals.
Daily treatment for a patient
0
10
20
30
40
50
60
70
80
90
100
Nov '06 Dec '06 Jan '07 Feb '07 Mar '07 Apr '07 May '07 TO DATE
Number of children under treatment (31st May 2007)
(000’s)
40,758 children already under
treatment
28,229 new children
TOTAL
3/ The first drugs already in the field… against HIV/AIDS
Pediatric ARV program with the Clinton foundation
Source: Clinton foundation
Atter 3 months After 5 monthsOn admission
Jennifer
Source: Partners In Health / Clinton foundation
Results obtained: Impact for a patient
Pediatric ARV program with the Clinton foundation
Arrival on 12th June 2007 of 670,000 ACT doses in Liberia that will help to prevent the death of 6,800 children per year(partners: UNICEF / WHO)
Against malaria