14 Central Quadrant Technique

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    12Oncoplastic Surgery: Central QuadrantTechniquesKristine E. Calhoun and Benjamin O. Anderson

    12.1 Introduction

    Breast-conserving therapy was introduced as an alternative to

    breast sacrifice for women affectedby breastcancer beginning

    in the 1970s and clinical trials have since demonstrated

    equivalency in terms of overall survival between lumpectomyplus radiation and mastectomy[1, 2]. Although there are clear

    contraindications to lumpectomy, for the appropriately

    selected individual, breast-conserving therapy offers both

    effective treatment and the psychological benefit of retention

    of the breast.

    In a traditional lumpectomy, there is no specific effort to

    obliterate the internal resection cavity. In fact, closing

    fibroglandular tissue can result in unsightly defects if

    alignment of the breast tissue is suboptimal. Fibroglandular

    tissue that is sutured closed at middle depth in the breast

    while the patient is supine on the operating table can result

    in a dimpled, irregular appearance when the patient stands

    up. Given this potential, most surgeons choose to close the

    skin of a lumpectomy without approximation of the

    underlying tissue. Although the simple scoop and run

    approach to lumpectomy may work well for small tumors,

    declivity of the skin and/or displacement of the nipple

    areola complex (NAC) may occur if the lesion removed

    from the breast is sizable and may create especially trou-

    bling defects for central lesions.

    For breast conservation to be effective, the primary

    tumor must be resected with adequate surgical margins

    while simultaneously maintaining the breasts shape and

    appearance, goals which may prove challenging and in

    some settings seem to be conflicting [3, 4]. In 1994,

    Audretsch [5] was one of the first to advocate the use of

    oncoplastic surgery for repair of partial mastectomy

    defects by combining the techniques of volume reduction

    with immediate flap reconstruction. Although initially used

    to describe partial mastectomy combined with large myo-cutaneous flap reconstruction using the latissimus dorsi or

    the rectus abdominis muscles, oncoplastic surgery now

    more commonly describes numerous surgical techniques

    that utilize partial mastectomy and breast-flap advancement

    to address tissue defects following wide resection.

    Compared with breast reconstruction using a myocutaneous

    flap, breast-flap advancements are easily learned and

    implemented by breast surgeons, even those lacking formal

    plastic surgery training.

    A comprehensive understanding of normal ductal anat-

    omy is critical to planning an oncoplastic partial mastec-

    tomy [3, 6]. The modern anatomic analysis of ductalanatomy suggests that the number of major ductal systems

    is probably fewer than ten [7]. The size of ductal segments

    is variable and whereas some ducts pass radially from the

    nipple to the periphery of the breast, others travel directly

    back from the nipple toward the chest wall. In contrast,

    well-defined breast vasculature allows the surgeon to

    remove and remodel large amounts of fibroglandular tissue

    without major risk of breast devascularization and/or tissue

    necrosis. The commonest sources of arterial blood supply in

    the human breast arise from the axillary and internal

    mammary arteries. By maintaining communication with one

    of these two arterial connections, one maintains an adequateblood supply for the breast parenchyma during tissue

    advancement and mastopexy closure.

    The use of oncoplastic surgical techniques for breast

    conservation allows wider resections without subsequent

    tissue deformity, and thereby allows surgeons to achieve

    wide surgical margins while preserving the shape and

    appearance of the breast [8]. Such techniques can be

    especially useful for more centrally located lesions, which

    when resected with standard surgical techniques may result

    K. E. Calhoun B. O. Anderson (&)

    Breast Health Clinic, Department of Surgery,

    University of Washington, Seattle, USA

    e-mail: [email protected]

    K. E. Calhoun

    e-mail: [email protected]

    C. Urban and M. Rietjens (eds.), Oncoplastic and Reconstructive Breast Surgery,DOI: 10.1007/978-88-470-2652-0_12, Springer-Verlag Italia 2013

    117

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    in suboptimal cosmetic outcomes. Although specific onco-

    plastic techniques differ from one another, all of the

    approaches involve fashioning the tissue resection to the

    anatomic shape of the cancer while ensuring that wide

    margins, ideally more that 1 cm, are achieved in an optimal

    number of patients [3, 6]. The indications and contraindi-

    cations for oncoplastic surgery are the same as those for

    traditional breast-conserving surgery, and such techniquesshould only be offered to those otherwise believed to be

    breast-preservation candidates on the basis of size and

    centricity.

    The techniques described in this chapter include those

    used for central segmental resections that utilize breast-flap

    advancement (so-called tissue displacement techniques) and

    include central lumpectomy, batwing mastopexy lumpec-

    tomy, donut mastopexy lumpectomy, and variations on

    reduction mastopexy lumpectomy which utilize a pedicle

    flap to restore the NAC.

    12.2 Preoperative Planning

    Patients undergoing central quadrant resections should

    undergo standard preoperative history taking and physical

    examination, with the elements of gynecologic, family, and

    social history, including smoking, emphasized. Special

    attention should be given to any prior breast surgical his-

    tory, including the placement of breast implants. Needle

    sampling should be performed to provide tissue diagnosis of

    malignancy. At our institution, internal review of all

    external pathology slides is required to confirm that we

    agree with the histopathologic diagnosis.

    Those being considered for oncoplastic resections should

    undergo a standard preoperative breast imaging workup,

    which typically includes some combination of mammog-

    raphy, ultrasonography, and in selected circumstances

    breast MRI. Although mammography may underestimate

    the extent of ductal carcinoma in situ by as much as

    12 cm, it is still warranted and is often the initial

    diagnostic study [9].

    Although controversial, the use of MRI may contribute to

    the surgeons ability to preoperatively determine the extent

    of disease, especially for mammographically subtle and/or

    occult cancers, and to conceptualize the location of the

    tumor more three-dimensionally than allowed on mam-

    mography. Compared with mammographic and ultrasono-

    graphic images, the extent of disease seen on MRI may

    correlate best with the extent of tumor found on pathologic

    evaluation. In addition, MRI has the lowest false-negative

    rate in detecting invasive lobular carcinoma [10]. Although

    its sensitivity for detection of invasive breast cancer is high,

    MRI unfortunately has a low specificity of 68 % in the

    diagnosis of breast cancer before biopsy [11]. Up to one-

    third of MRI studies will show some area of enhancement

    that needs further assessment that ultimately proves to be

    histologically benign breast tissue [3]. A consensus state-

    ment from the American Society of Breast Surgeons [12]

    updated in 2010 supports the use of MRI for determining the

    extent of ipsilateral tumor or the presence of contralateral

    disease in patients with a proven breast cancer (especially

    those with invasive lobular carcinoma) when dense breasttissue precludes an accurate mammographic assessment. For

    cancers containing both invasive and noninvasive compo-

    nents, a combination of imaging methods may yield the best

    estimate of overall tumor size [13].

    12.3 Perioperative Planning

    Once a central oncoplastic approach has been selected,

    decisions regarding the use of preoperative wire localization

    for nonpalpable malignancies must be made. In planning

    oncoplastic resections, the surgeon needs to accurately

    identify the area requiring removal. Silverstein et al. [14]

    suggested the preoperative placement of two to four brac-

    keting wires to delineate the boundaries of a single lesion.

    In a study by Liberman et al. [15], wire bracketing of 42

    lesions allowed complete removal of suspicious calcifica-

    tions in 34 patients (81.0 %). It has been suggested that

    single wire localization of large breast lesions is likelier to

    result in positive margins, because the surgeon lacks land-

    marks to determine where the true boundaries of nonpal-

    pable disease are located. For such scenarios, multiple

    bracketing wires may assist the surgeon in achieving

    complete excision at the initial intervention. For more pal-

    pable lesions, such wire localizations may be a moot point.

    Skin landmarks should be marked with the patient sitting

    up in the preoperative area, including the inframammary

    crease, the anterior axillary fold at the pectoralis major mus-

    cle, the posterior axillary fold of the latissimus dorsi muscle,

    the sternal border of the breast, and the periareolar circle.

    Identifying these entities with the patient in the upright

    position is very important for the final cosmetic outcome,

    because these anatomic sites may prove challenging to

    accurately locate once the patient is anesthetized and lying

    supine on the operating room table. Generally, for reduction-

    type procedures, markings will be placed on both breasts.

    For all oncoplastic techniques, the patient should be

    supine on the operating room table and with both arms

    abducted on arm boards and secured. It is preferable to have

    both breasts prepared and draped into the field so that visual

    comparison with the patient in a beach chair position is

    possible as the wound is closed. Such an approach allows

    the surgeon to identify any areas of unnecessary tugging or

    dimpling which are inadvertently created so that they can be

    corrected.

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    12.4 Central Quadrant Techniques

    12.4.1 Central Lumpectomy

    For those cancers involving the NAC, including Pagets

    disease of the nipple, the cosmetic impact of nipple removal

    with central lumpectomy typically accounts for the common

    use of mastectomy in this situation. In recent years, withimproved NAC reconstructive capabilities, central lump-

    ectomies have been utilized more. Although central lump-

    ectomy removes the NAC and underlying central tissues, it

    typically leaves behind a significant breast mound, espe-

    cially for those with larger breasts at the baseline. The

    cosmetic outcome with central lumpectomy can range from

    good to outstanding, depending on the womans body

    habitus, and is likely to be better tolerated than recon-

    struction of an entire breast [3]. Central lumpectomy can be

    particularly valuable in women with large breasts where

    loss of the entire breast with mastectomy may create

    prominent asymmetry. Surgical issues of NAC reconstruc-

    tion in an irradiated field, including wound-healing issues

    and NAC loss, must be considered, so early referral for

    plastic surgery is warranted.

    In central lumpectomy, the incision can be made in the

    pattern of a large parallelogram that encompasses the entire

    NAC, or can be more circular in nature (Fig. 12.1af). Afterexcision of the skin island/NAC, short-distance mastec-

    tomy-type skin flaps are raised along both sides of the

    wound. The dissection is carried down to the chest wall and

    the breast gland is lifted off the pectoralis muscle. After

    full-thickness excision of the tumor, four to six marking

    clips are typically placed at the base of the defect within the

    surrounding fibroglandular tissue for future imaging and

    radiation oncology purposes. A small drain may also be

    placed in the lumpectomy wound in cases where the

    Fig. 12.1 Central lumpectomy.a Preoperative marking with the

    patient in the upright position.

    b Intraoperative marking with the

    patient in the supine position

    illustrating positional shift of the

    breast landmarks. c Initial skin

    incision revealing wide exposure

    over the target lesion. d Central

    resection. e Postexcision cavity.

    f Final closure

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    dissection is more extensive and fear of seroma is increased.

    For adequate evaluation of margin status by the pathologist,

    sharp rather than cautery dissection should be considered, as

    sharp dissection will not alter the histological margins of the

    resected tissues with the so-called cautery effect. Larger

    intraparenchymal vessels can be ligated or coagulated dur-

    ing the dissection, and cautery can then be used on the

    exposed fibroglandular tissue faces to control bleeding.Once tissue specimens have been resected and hemos-

    tasis has been obtained, the fibroglandular tissue at the level

    of the pectoralis fascia is undermined so that breast-tissue

    advancement can be performed over the muscle. Once the

    fibroglandular tissues have been sufficiently mobilized and

    hemostasis has been confirmed, the margins of the residual

    cavity are shifted together by the advancement of breast

    tissue over muscle and the defect is sutured at the deepest

    edges using 3-0 absorbable sutures. The direction of tissue

    advancement can be adjusted depending upon the location

    of the fibroglandular defect and the excess tissue that can be

    shifted to close it. The goal of the mastopexy is to perform

    as complete a closure over the pectoralis muscle as possible

    to discourage communication between the anterior skin and

    the deeper tissues. Side to side comparisons with the patient

    in an upright position are warranted to ensure that no

    unusual retractions of the tissues or unsightly cosmetic

    results have occurred.

    The superficial tissue layer is next closed with an inter-

    rupted subdermal 3-0 absorbable suture, and the skin is

    closed with 4-0 absorbable subcuticular sutures in routine

    fashion. Two variations on closure exist. The first, which is

    more typical, involves closure in a manner which results in

    a scar that is a horizontal, straight line, and the second

    involves closing the wound utilizing a purse-string closure

    to facilitate areolar tattooing.

    12.4.2 Batwing Mastopexy Lumpectomy

    For cancers adjacent to or deep to the NAC, but without

    direct involvement of the nipple, lumpectomy can suc-

    cessfully be performed without sacrifice of the nipple itself.

    The batwing approach preserves the viability of the NAC

    while preserving the breast mound by using mastopexy

    closure to close the resulting fibroglandular defect of the

    full-thickness resection. This procedure may result in lifting

    of the nipple into the upper breast, and a contralateral lift

    may need to be performed to achieve symmetry, especially

    when the native breast is large and pendulous.

    Two similar semicircle incisions are made with angled

    wings on each side of the areola (Fig. 12.2ae). The two

    half-circles are positioned so they can be reapproximated to

    each other at wound closure. Removal of these skin wings

    allows the two semicircles to be shifted together without

    creating redundant skin folds at closure. Fibroglandular

    tissue dissection is carried down deep to the known cancer,

    with the depth in relation to the chest wall dictated by the

    position of the lesion within the breast. In most situations,

    the dissection is carried down to the chest wall and the

    breast gland is lifted off the pectoralis muscle in a fashion

    similar to that for central lumpectomy. The principles of

    sharp dissection and the placement of marking clips are alsosimilar to those utilized in central lumpectomy.

    Following full-thickness resection of the target, mobili-

    zation of the fibroglandular tissue for mastopexy closure

    will likely be required. The breast tissue is elevated off of

    the chest wall at the plane between the pectoralis muscle

    and breast gland, and the fibroglandular tissue is advanced

    to close the resulting defect. The deepest parts are

    approximated by interrupted sutures. We typically secure

    the fibroglandular tissue to fibroglandular tissue and do not

    place anchoring stitches into the chest wall, thereby

    allowing the approximated breast tissues to move along the

    chest wall. The superficial layer is closed in the same

    fashion as in central lumpectomy. As this procedure can

    cause some lifting of the nipple, it may create asymmetry

    compared with the noncancerous breast. A contralateral lift

    can be performed after adjuvant radiation therapy has been

    completed and the treated breast has declared its new size

    and shape to achieve symmetry, although some plastic

    surgeons may choose to perform this symmetry procedure

    concurrent with the oncologic surgery.

    12.4.3 Donut Mastopexy Lumpectomy

    For segmentally distributed cancers located in the upper or

    lateral breast that approach the NAC, donut mastopexy

    lumpectomy can be used to achieve effective resection of

    long, narrow segments of breast tissue. Donut mastopexy

    avoids a visible long radial scar which is against Kraissls

    line or Langers line. In this procedure (Fig. 12.3af), two

    concentric lines are placed around the areola and a peri-

    areolar donut skin island is excised, with only a peri-

    areolar scar visible after this operation. Deepithelialization

    by separating this skin island from the underlying tissues is

    done, taking care to avoid full devascularization of the

    areolar skin. The width of the donut skin island should be

    approximately 1 cm, but is somewhat dependent on the size

    of the areola and the expected extent of excision. Removal

    of this tissue ring is required, as it allows both adequate

    access to and exposure of the breast tissue and closure of the

    skin envelope around the remaining fibroglandular tissue

    that will reduce tissue volume overall.

    A skin envelope is created in all directions around the

    NAC. The quadrant of breast tissue containing the target

    lesion is fully exposed utilizing the same dissection used for

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    a skin-sparing mastectomy. The full-thickness breast gland

    is then separated from the underlying pectoralis muscle and

    delivered through the circumareolar incision. The segment

    of breast tissue with the tumor is resected in a wedge-

    shaped fashion, with the width of tissue excision required to

    achieve adequate surgical margins balanced against the

    difficulty that will be created by virtue of an oversized

    segmental defect.The remaining fibroglandular tissue is returned to the

    skin envelope and the peripheral apical corners of the

    fibroglandular tissue are secured to each other and then

    anchored to the chest wall. This anchoring step maintains

    proper orientation of the mobilized fibroglandular tissue

    within the skin envelope during the initial phases of healing.

    A purse string using a 3-0 absorbable suture is placed

    around the areola opening, and is clamped at a size that

    reapproximates the original NAC. Interrupted inverted 3-0

    absorbable sutures are placed subdermally around the NAC,

    at which time the purse-string suture is tied and then 4-0

    subcuticular sutures are used to close the wound. Uplifting

    of the NAC may create mild asymmetry in comparison with

    the untreated breast. If desired, a contralateral lift can be

    performed to achieve symmetry.

    12.4.4 Reduction Mastopexy LumpectomyModifications

    Initially used in women with macromastia and excessive

    breast ptosis, this procedure is currently used for resection

    of lesions in the lower hemisphere of the breast between the

    4 oclock and 8 oclock positions, where scoop and run

    lumpectomy using circumareolar incision would result in

    unacceptable down-turning of the nipple owing to scar

    Fig. 12.2 Batwing mastopexylumpectomy. a Preoperative

    marking with the patient in the

    upright position. b Intraoperative

    marking with the patient in the

    supine position. c Resection

    cavity. d Final closure.

    e Postoperative result with the

    patient in the upright position

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    contracture after radiotherapy. This unpleasant cosmetic

    outcome can be prevented by using the technique of

    reduction mastopexy lumpectomy (Fig. 12.4af). Recently,

    the indications for using reduction techniques have been

    expanded to include women with centrally located tumors

    faced with NAC loss. In these situations, the reduction is

    coupled with a deepithelialized pedicle flap with an over-

    lying skin island to recreate the NAC, ultimately resulting

    in a Wise-type scar and a neo-nipple [16].In traditional reduction mammoplasty, a keyhole pattern

    incision is made and the skin above the areola is deepi-

    thelialized in preparation for skin closure. A superior ped-

    icle flap is created by inframammary incision and

    undermining of the breast tissue off the pectoral fascia to

    mobilize the NAC and underlying tissues. Mobilization of

    the breast tissue allows palpation of both the deep and the

    superficial surfaces of the tumor, which can aid the surgeon

    in determining the lateral margins of excision around the

    target lesion. When it is used for a central lesion, the pri-

    mary tumor and overlaying NAC are resected down to the

    chest wall. The principle of sharp dissection and the

    placement of marking clips are the same as those for par-

    allelogram mastopexy lumpectomy. A caudally located

    inferior flap is then deepithelialized, except for an appro-

    priately sized skin island that will function as the neo-nip-

    ple. Following this, redundant medial, lateral, and superior

    tissues are then resected while preserving the pedicle tissue.An incision at the inframammary crease facilitates mobili-

    zation and assists in restoration of normal breast shape and

    contour.

    Once all tissues have been resected, the central, inferior

    pedicle is mobilized, brought cephalad, and utilized to

    occupy the defect created by removal of the prior NAC. The

    neo-nipple is sutured to the margins of NAC resection. The

    medial and lateral breast flaps are undermined and sutured

    together to fill the excision defect, leaving a typical

    Fig. 12.3 Donut mastopexylumpectomy. a Preoperative

    marking including marking of the

    region to be removed based on

    preoperative bracketing wires

    and concentric circles for skin

    donut excision. b Initial skin

    incision. c Delivery of tissue

    segment through the periareolar

    incision. d Remaining cavity

    after resection. e Purse-string

    closure. f Final operative result

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    inverted-T scar. Variations of this technique have been

    reported, including the Grisotti flap, which extends the

    pedicle laterally and results in an inferior and laterally

    sweeping incision [16], and free nipple graft from the skin

    of the contralateral reduction tissue [17]. Finally, some

    choose to utilize the reduction flap without creation of a

    neo-nipple, leaving the patient with a Wise-type incision

    and the choice of NAC in a delayed fashion [16].

    12.5 Postoperative Management

    Although drains are rarely required in standard partial

    mastectomy cases, with more extensive dissections, such as

    donut mastopexy lumpectomy, fluid accumulation can

    become more pronounced and require postoperative aspi-

    ration. In recent years, we have started to place small, 15F

    drains overnight to avoid excessive fluid accumulation in

    the dissected breast that might distort the oncoplastic clo-

    sure. These drains are typically removed either prior to

    discharge or on the first postoperative day in the clinic.

    12.6 Complications

    When using central oncoplastic approaches, surgeons with-

    out formal plastic surgery training must determine whichprocedures they are comfortable performing without plastic

    surgery consultation or intraoperative collaboration [3].

    Although these techniques appear to be relatively safe in the

    immediate postoperative period, issues such as wound

    infection, fat necrosis, and delayed healing with the more

    advanced techniques are all potential, reported complications

    [1820]. Despite more extensive resections, hematomas

    requiring reoperation appear to be infrequent, occurring

    roughly 23 % of the time in two recent studies [19, 20]. The

    Fig. 12.4 Reduction mastopexylumpectomy. a Preoperative skin

    markings showing the keyhole

    incision pattern. b Initial skin

    incision. c Full-thickness

    resection. d Excised specimen

    and residual cavity. e Closure.

    f Final result

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    blood supply of the external nipple arises from underlying

    fibroglandular tissue using major lactiferous sinuses rather

    than the collateral circulation from surrounding areolar skin,

    so nipple necrosis may occur if dissection extends high up

    behind the nipple, but is also fortunately rare [3]. Finally, in a

    review of 84 women who underwent partial mastectomy and

    radiation therapy, Kronowitz et al. [21] showed that

    immediate repair of partial mastectomy defects with localtissues results in fewer complications (23 vs. 67 %) and

    better aesthetic outcomes (57 vs. 33 %) than that with a

    latissimus dorsi flap, which some surgeons used for delayed

    reconstructions [22].

    12.7 Results

    The main goal of oncoplastic lumpectomy remains negative

    surgical margin resection. Complete excision of calcified

    lesions and masses should be confirmed with specimen

    radiography during surgery. Additional oriented margins

    can be resected prior to mastopexy closure when the

    radiograph suggests inadequate resection may have occur-

    red, hopefully eliminating the need for a delayed re-exci-

    sion. Although some centers use intraoperative analysis

    with a frozen section to aid in decisions regarding the

    resection of additional segments of tissue, thus is not our

    policy.

    Multicolored inking performed by the surgeon in the

    operating room helps to improve margin identification.

    Inking kits are now available with six colors (black, blue,

    yellow, green, orange, and red), which are very useful for

    labeling all of the surgical margins (superior, inferior,

    medial, lateral, superficial, and deep) (Fig. 12.5). Clear

    uniformity between the surgeon and the pathologist in terms

    of what color means what margin is required, especially

    when inadequate margins are identified that require

    reoperation.

    Although the historical gold standard for a negative

    surgical margin has been 10 mm, what constitutes a true

    negative margin differs widely from center to center,

    with 3 mm or greater accepted at our institution. Low local

    recurrence rates after breast conservation therapy, espe-

    cially in the era of postlumpectomy irradiation, can be

    achieved with an intermediate surgical margin width

    between 1 and 10 mm [1, 2]. If re-excision is needed for

    inadequate surgical margins following the initial resection,

    both the surgical approach and the timing of the operation

    must be considered [3]. When the positive margin involves

    a minority of the specimen, the entire biopsy cavity does not

    need to be re-excised, and instead can be directed toward

    the inadequate region. If re-excision is delayed for

    34 weeks, the previous seroma cavity may be nearly

    reabsorbed, which leaves a fibrous biopsy cavity that can be

    easily located by intraoperative palpation. With noninvasive

    cancer, Silverstein et al. [14] have suggested that it is fea-sible to delay re-excision for up to 3 months, at which point

    the seroma cavity has been fully reabsorbed.

    When all the resection margins are positive, mastectomy

    may be needed to attain satisfactory surgical clearance. In

    this instance, it may be technically challenging to include

    both the initial oncoplastic incision and the NAC in a

    subsequent total mastectomy, and consultation with the

    plastic surgeon in the event of immediate postmastectomy

    reconstruction is mandatory. Despite a clear ability to resect

    widely with these central oncoplastic techniques, inade-

    quate margins remain an issue. Although reports remain

    sparse, reported rates of inadequate margins following ini-tial resection range from 8 to 22 % [19, 20, 2328]. The

    decision between a re-excision and a mastectomy must be

    based on the operating surgeons ability to appropriately

    localize the involved region, and with more advanced

    resections this may only be possible with breast sacrifice.

    Although large studies of long-term outcomes specifi-

    cally addressing oncoplastic approaches in breast conser-

    vation are lacking, the limited available results continue to

    look promising. One investigation from Europe followed

    148 women for a median of 74 months (range

    10108 months) and only two were lost to follow-up.

    Among the 146 individuals available for analysis, there

    were only five women (3 %) who had an ipsilateral in-

    breast cancer recurrence after 5 years and all had either T2

    or T3 tumors at presentation. Rietjens et al. [29] argued that

    recurrence rates for women with oncoplastic resections and

    concurrent radiation therapy were comparable to the in-

    breast recurrence rates reported with standard breast con-

    servation techniques. Studies of more limited follow-up

    recently reported no in-breast local recurrences at

    26 months [19], 38 months [20], and 34 months [16],

    Fig. 12.5 Specimen inked by the surgeon to designate anterior,posterior, medial, lateral, inferior, and superior margins

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    although some distant recurrences were reported. These

    results appear equivalent to those for women treated with

    traditional lumpectomy and should serve to allay any fears

    of cosmesis being favored over cancer control.

    12.8 Conclusions

    Although shown to be a reasonable alternative to mastec-

    tomy for the appropriately selected breast cancer patient,

    traditional scoop and run lumpectomy may result in poor

    cosmesis. Central oncoplastic techniques, including central

    lumpectomy, batwing mastopexy lumpectomy, donut mas-

    topexy lumpectomy, and variations of reduction mastopexy

    lumpectomy have been developed to address this issue. By

    combining large-volume tumor removal with breast-flap

    advancements, the oncoplastic approaches allow wider

    margins of resection and better breast shape and contour

    preservation. Candidates are those felt to be standard

    lumpectomy candidates and include those with no evidence

    of multicentric disease.

    Standard preoperative workup, including dedicated

    breast imaging, and preoperative wire localization are

    necessary to aid the surgeon in successful resection. Com-

    plications of tissue necrosis are fortunately rare, despite

    sometimes significant remodeling of the fibroglandular tis-

    sues due to the breasts rich blood supply. Outcomes appear

    at least equivalent to those for standard breast conservation

    techniques, although large case series are lacking. Despite

    this paucity of long-term results, oncoplastic lumpectomy

    can be learned by individuals familiar with breast surgical

    techniques and generally results in better cosmesis and

    equivalent oncologic outcomes.

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