Program Director:Ziad M. El-Zoghby, M.D.

Planning Committee:Hatem Amer, M.D.Ziad M. El-Zoghby, M.D.Suzanne M. Norby, M.D.Sandra J. Taler, M.D.

REGISTER ONLINE NOW!http://www.mayo.edu/cme/nephrologyupdate2013

12th AnnualMayo Clinic Update in Nephrology and Kidney Transplantation

Mayo School of Continuous Professional Development

SEPTEMBER 20-21, 2013The Depot Renaissance Minneapolis225 South 3rd AvenueMinneapolis, MN 55401

PROGRAM HIGHLIGHTS:•InternationalGuestFaculty•UltrasoundWorkshop•InteractiveCase-BasedDiscussions

“I enjoyed this conference. I attended for the first time and intend

to come back.”

“Full of knowledgeable speakers and very warm

staff and speakers.”

General Information

Course DescriptionThe Annual Update in Nephrology and Kidney Transplantation is a two-day course designed to update participants on a range of nephrology topics relevant to current medical practice.

Topics include:•chronickidneydisease•hypertension•glomerulardiseases•dialysis•kidneytransplantation

Through a combination of lectures, literature review, and case-based presentations, this course will deliver up-to-date and cutting edge information that can be directly integrated into clinical practice.

*Inaddition,anintroductoryworkshop“Bedside Ultrasonography for the Nephrologist” will be offered Saturday morning. This 4 hourhands-onworkshopprovidesparticipants with techniques used to acquire ultrasoundimagesofthekidneys,bladderand large vessels and guidance in recognizing common pathology detected by ultrasound. An additional fee of $90 is required to participateinthisworkshop,andspaceislimited to the first 9 participants. Sign up for this session on the registration website.

The course provides ample opportunity for interaction with expert faculty. This year we are partnering with United Kingdom Renal Association to add a strong international presence of guest faculty to the program. We continue to feature the popular audience responsesystemtomaximizespeakerandattendee interactions. A comprehensive on-line syllabus will be available for future reference.

Attendees are encouraged to bring laptops or iPads for viewing during the course.

Course Learning ObjectivesAt the completion of this course, participants should be able to:•Appraiserecentpublicationsindialysisand

hypertension•Summarizerecentclinicaltrialoutcomes

related to management of cardiovascular riskinCKD

•Recognizeandmanagemonoclonalgammopathy of renal significance

•Selectbesttreatmentstrategiesformembranous nephropathy and ANCA vasculitis

•Describenewresearchdevelopmentsinkidneytransplantation

•Identifystrategiestopreventlongtermkidneyallograftloss

FortheBedsideUltrasonographyWorkshop:•Performultrasoundofthekidneys,bladder,

large vessels and lungs•Recognizecommonpathologydetectedby

ultrasound examination•Reviewandapplytheprinciplesofcentral

line placement

Attendance at this Mayo course does not indicate nor guarantee competence or proficiency in the performance of any procedures which may be discussed or taught in the course.

Intended AudienceThis course is intended for all members of the nephrology community and will be of interest to nephrologists, nephrology trainees, nurse practitioners, physician assistants, nurses, patient care technicians, pharmacists, internists, primary care physicians and other specialists who participate in the care of patientswithkidneydisordersandkidneytransplants.

CreditCollege of Medicine, Mayo Clinic, is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

College of Medicine, Mayo Clinic, designates this live activity for a maximum of 15 AMA PRA Category 1 Credits™. Physicians should claim only those credits commensurate with the extent of their participation in the activity.

RegistrationTo register online, visit http://www.mayo.edu/cme/nephrologyupdate2013. The registration fee includes tuition, comprehensive electronic course syllabus, continentalbreakfasts,breakrefreshments,and reception. Although it is not Mayo Clinic policy to limit the number of registrants for a course, conference room facilities may necessitate closing of enrollment; therefore, early registration is advised. A letter of confirmation will be sent electronically upon

receipt of payment. Please present the confirmationletterwhencheckinginatthemeetingregistrationdesk.

Foradditionalinformation,contact:Mayo Clinic (Update in Nephrology) 200 First Street SW/GO6-472Rochester, MN 55905

Website: http://www.mayo.edu/cme/nephrologyupdate2013

E-mail: rstdomcme@mayo.eduPhone: 800-283-6296 or 507-266-6703Fax: 507-266-7403

TravelMinneapolis, Minnesota is a friendly city that greets thousands of visitors from around the world each year. The city is serviced by the Minneapolis/St. Paul International Airport with multiple flights daily. Access to and from the airport is provided by taxi, shuttle service, light rail and rental car. The airport is located approximately 13 miles from the The Depot Renaissance. Driving directions can be found at: http://www.thedepot minneapolis.com/directions.php

Travel arrangements are the sole responsibility of the individual registrant.

Date and LocationThe Annual Update in Nephrology and Kidney Transplantation course will be held September 20-21, 2013. Course headquarters will be located at The Depot Renaissance, 225 South 3rd Avenue, Minneapolis, MN 55401 in the Hiawatha Ballroom on the main floor.

Lodging AccommodationsWith a prime location in the heart of downtown, just steps away from the business district, local shopping and entertainment, The Depot Renaissance offers guests warm hospitality, an inviting atmosphere and stylishaccommodations.Itiswithinwalkingdistance to local attractions, including Hennepin Avenue’s famous entertainment venues, theaters and shops, as well as Mall of America Field and Target Center.

ThisisthehistoricMilwaukeeRoadDepothotel. The last train left in 1971, but The Depot still stands as a monument to romantic, adventurous rail days gone by. For nearly seven decades, family members and loved ones stood at the atrium of the Depot and waved to passengers boarding the trains of theMilwaukeeRoadline.Aprosperoushub

of business and personal travel, this was the place where ambition set forth, destinies converged, and hearts became one. In 1998, the MCDA approved a land sale to CSM Corporation for the development at The Depot. The complex includes The Depot Renaissance Minneapolis Hotel, the Residence Inn Minneapolis Downtown by Marriott, an indoorwaterpark,aninterpretivehistorycenter about the Depot, The Stone Arch Bar, Charley’s Restaurant, banquet space, and undergroundparkingfor650automobiles.

Guest rooms have been reserved for attendees and their guests at a special course rate of $139 single/double at The Depot Renaissance in Minneapolis, MN. To receive the course rate, reservations must be made before the roomblockisfilledorbyThursday,August22, 2013 whichever comes first. Reservations willbetakenfollowingthisdatebasedonspaceandrateavailability.Tomakeyourreservation, please call 612-375-1700 or 866-211-4611andaskforMayoNephrologydiscount.

Check-in: 3:00p.m.Check-out: 12:00p.m.

Lodging arrangements are the sole responsibility of the individual registrant.

Mayo School of CPD is not responsible for expenses incurred by an individual who is not confirmed and for whom space is not available at the meeting. Costs incurred by the registrant such as airline or hotel fees or penalties are the responsibility of the registrant.

Transportation/ParkingMetered taxis from the Minneapolis-St. Paul airport to the hotel are available at the cab starter booth. Fares average $28.00. There is a surcharge to and from the airport of $2.00. A Limo and Towncar service is available throughtheconciergedesk.Averageratestoand from the airport run from $35.00 to $100.00. Rental car companies have phones on the Baggage Claim Level opposite carousels 2, 5, and 10. A bus service is available from the Airport Transit Plaza and the approximate fare is $2.25. There is also a shuttle service available through Super Shuttle, costing an average of $13.00 one-way. The Light Rail line from the airport passes approximately3blocksSouthofthehotel.

Selfandvaletparkingareavailableatthehotel for an additional fee.

General Information

Social ActivitiesWelcomeReceptionFriday,September20,2013–5:45-7:00p.m.Attendees and their guest(s) are cordially invited to join the course faculty for the Welcome Reception on Friday, September 20, 2013 in the Soo Line and Hiawatha Foyer on the main floor. This casual reception welcomes you to Minneapolis, and offers you theperfectopportunitytomakeconnectionswith existing and new colleagues.

Leisure ActivitiesTheDepotRenaissanceislocatedafewblocksfrom major downtown shopping centers, cafes, restaurants, and theatres. In addition, thehotelincludesanindoorwaterpark.

Mall of America, the largest fully-enclosed retail and family entertainment complex in the United States, is an easy 20-minute drive from the hotel. Along with 500 retail stores, restaurants, and nightclubs, the mall features anindoorthemeparkandanaquarium.

For additional information and a full calendar of events, you may visit the Minneapolis Convention and Visitors Bureau. http://www.minneapolisdid.com/page/show/ 207241-calendar

FacultyCourse DirectorZiad M. El-Zoghby, M.D.

Planning CommitteeHatem Amer, M.D.Ziad M. El-Zoghby, M.D. Suzanne M. Norby, M.D.Sandra J. Taler, M.D.

MayoFacultyChristian L. Baum, M.D.Maria L. Collazo-Clavell, M.D.Fernando G. Cosio, M.D.Fernando C. Fervenza, M.D., Ph.D.Vesna D. Garovic, M.D.Joseph P. Grande, M.D., Ph.D.Marie C. Hogan, M.D., Ph.D.Kianoush B. Kashani, M.D.Timothy S. Larson, M.D.Nelson Leung, M.D.James T. McCarthy, M.D.Sanjay Misra, M.D.Mikel Prieto, M.D.Fawad M. Qureshi, M.D.Gary L. Schwartz, M.D.Hiroshi Sekiguchi, M.D.Ulrich Specks, M.D.

Mark D. Stegall, M.D.Sandra J. Taler, M.D.Hani M. Wadei, M.D.

GuestFacultyPaul Cockwell, MB BCh, Ph.D., FRCPQueen Elizabeth Hospital of Birmingham, Birmingham UK

Indranil Dasgupta, M.D., DM, FRCPHeartlands Hospital, Birmingham, UK

Mark Devonald, Ph.D., MRCPNottingham University Hospitals, Nottingham, UK

Matthew Hall, MB, BChir, M.D., MRCPNottingham Renal and Transplant Centre, Nottingham, UK

Bruce Hendry, M.D., Ph.D.King’s College, London, UK

Paul E. Stevens, MB BS BSC, FRCPKent and Canterbury Hospital, Canterbury, UK

David C. Wheeler, M.D., FRCPUCL Medical School, London, UK

Faculty DisclosureAs a provider accredited by ACCME, College of Medicine, Mayo Clinic (Mayo School of Continuous Professional Development) must ensure balance, independence, objectivity and scientific rigor in its educational activities. Course director(s), planning committee, faculty, and all others who are in a position to control the content of this educational activity are required to disclose all relevant financial relationships with any commercial interest related to the subject matter of the educational activity. Safeguards against commercial bias have been put in place. Faculty also will disclose any off-label and/or investigational use of pharmaceuticals or instruments discussed in their presentation. Disclosure of this information will be published in course materials so those participants in the activity may formulate their own judgments regarding the presentation.

Grants and ExhibitsAt the time of this printing, a complete listing of commercial supporters (financial or in-kind)wasnotavailable.Appropriateacknowledgmentwillbegiventoallsupporters at the time of the meeting.

Exhibits will be available for viewing at all scheduledbreaks.

General Information

Program ScheduleFriday, September 20, 2013

7:00 a.m. Registration and ContinentalBreakfast Hiawatha Foyer, Main Floor

7:45 a.m. IntroductionandWelcome Ziad M. El-Zoghby, M.D.

7:50 a.m. Pre-Test Ziad M. El-Zoghby, M.D.

MORNINGSESSIONI–ESRDTOPICS

8:00 a.m. LiteratureUpdateinDialysis James T. McCarthy, M.D.

8:30 a.m. PredialysisCareandDialysis intheVeryElderly Indranil Dasgupta, M.D.

9:00 a.m. InterventionalNephrologyTopics

Fawad M. Qureshi, M.D. and Sanjay Misra, M.D.

10:00 a.m. RefreshmentBreak Hiawatha Foyer

MORNINGSESSIONII–CKD AND HYPERTENSION

10:20 a.m. UKExperienceofCKDDetection, Outcomes, and InterventionandtheEffectofNICE Recommendations

Paul E. Stevens, MB BS BSC

10:50 a.m. T-TypeCalciumChannelInhibitorsasPotentialTherapeutics in Renal Disease

Bruce Hendry, M.D., Ph.D.

11:20 a.m. LiteratureUpdateinHypertension

Gary L. Schwartz, M.D.

12:00 p.m. Lunch RockIsland–MainFloor

AFTERNOONSESSIONI–GENERAL NEPHROLOGY

1:15 p.m. CardiovascularRiskManagementinCKD:WhatHaveWeLearnedFromRecentClinical Trials?

David C. Wheeler, M.D.

1:55 p.m. DermatologyfortheNephrologist

Christian L. Baum, M.D.

AFTERNOONSESSIONII–DYSPROTEINEMIA

2:35 p.m. UpdateonDysproteinemiaI Nelson Leung, M.D.

3:05 p.m. UpdateonDysproteinemiaII Paul Cockwell, MB BCh, Ph.D.

3:35 p.m. RefreshmentBreak Hiawatha Foyer

AFTERNOONSESSIONIII–PARENCHYMAL DISEASE

3:55 p.m. Therapeutic Approaches Based on Pathogenic Knowledge in MembranousNephropathy

Fernando C. Fervenza, M.D., Ph.D.

4:25 p.m. RenalPathologyRoundTable Drs. Fernando C. Fervenza, Joseph P. Grande, and Timothy S. Larson

5:30 p.m. Adjourn

5:45- WelcomeReception7:00 p.m. Soo Line & Hiawatha Foyer All faculty, participants, and

their guests are invited.

Saturday, September 21, 2013

7:30 a.m. ContinentalBreakfast Hiawatha Foyer

– Continued on next page.

Future Dates

September19-20,2014The Depot Renaissance

Minneapolis, MN

CONCURRENTSESSION:TRANSPLANTUPDATES

8:00 a.m. Steroid-FreeImmunosuppression

Timothy S. Larson, M.D.

8:30 a.m. KidneyDysfunctionintheCirrhoticPatient:WhentoListMyPatientforCombinedLiver-KidneyTransplantation(Case-Based)

Hani M. Wadei, M.D.

9:10 a.m. PairedKidneyDonation–CurrentStatus

Mikel Prieto, M.D.

9:40 a.m. RefreshmentBreak Hiawatha Foyer

10:00 a.m. UpdateonUNOSLiving Donor Policies Sandra J. Taler, M.D.

10:30 a.m. What’sHot,What’sNewinTransplantation?

Mark D. Stegall, M.D.

11:00 a.m. TheObeseTransplantCandidate–ManagementOptions

Maria L. Collazo-Clavell, M.D.

11:30 a.m. RiskstoLong-Term AllograftSurvival Fernando G. Cosio, M.D.

12:00 p.m. Lunch RockIsland–MainFloor

CONCURRENTSESSION:BEDSIDEULTRASONOGRAPHYFORTHENEPHROLOGIST:HANDS-ONWORKSHOPLocation: Soo Line* Note, there is an additional $90 fee for this workshop. See Course Description for details.

8:00 a.m. - BedsideUltrasonographyfor12:00 p.m. the Nephrologist: Hands-on

Workshop Kiansoush B. Kashani, M.D. and

Hiroshi Sekiguchi, M.D.

8:00 a.m. BasicPrinciplesofUltrasonography

(PhysiologyandKnobology)

8:15 a.m. KidneyandBladderUltrasonography

8:30 a.m. UltrasonographytoAssessVolume Status

8:45 am. Hands-on Sessions: •KidneyandBladder •VascularAccess:Jugular Vein Cannulation

9:40 a.m. RefreshmentBreak Hiawatha Foyer

10:00 a.m. Hands-on Sessions: • Lungs • InferiorVenaCava/Aorta (CVP and Volume Status)

11:00 a.m. Interpretation: Practice InterpretingAbnormalStudies

12:00 p.m. Lunch RockIsland–MainFloor

AFTERNOONSESSIONI–ACUTEKIDNEYINJURYANDCRITICALCARE

1:00 p.m. UpdateinCriticalCareMedicine

Kianoush B. Kashani, M.D.

1:30 p.m. AcuteKidneyInjury Mark Devonald, Ph.D.

AFTERNOONSESSIONII–VASCULITISANDCYSTICDISEASES

2:00 p.m. ANCA Vasculitis Ulrich Specks, M.D.

2:30 p.m. PolycysticKidneyDiseaseUpdate

Marie C. Hogan, M.D., Ph.D.

3:00 p.m. RefreshmentBreak Hiawatha Foyer

AFTERNOONSESSIONIII–THEKIDNEYIN PREGNANCY

3:20 p.m. ManagementofCKDinPregnancy

Matthew Hall, MB, BChir, M.D.

3:50 p.m. A Case-Based Approach to Managing Lupus Nephritis in Pregnancy

Vesna D. Garovic, M.D.

4:30 p.m. Post-Test Ziad El-Zoghby, M.D.

5:00 p.m. Adjourn

REGISTRATIONRegister online:

http://www.mayo.edu/cme/nephrologyupdate2013

RegistrationFee:CourseRegistration(MD,PhD,DO,PharmD) $450.00CourseRegistration(Resident,PA,NP,RN) $305.00OneDayFee(NursesOnly) $150.00UltrasoundWorkshop(SaturdayMorning) $90.00(additional cost to attendees who have registered for the general session)

Mayo Clinic Department of Internal Medicine uses an online conference registration system. If this is your first time using the online system, you will need to create a profile and login account. The attendee’s email address is required upon registration.

Registration is only available online at: http://www.mayo.edu/cme/nephrologyupdate2013A letter of confirmation and receipt will be forwarded to this email address upon receipt of submitted registration and payment. Please present the confirmation letterwhencheckinginatthemeetingregistrationdesk.

The registration fee includes tuition, comprehensive on-line course syllabus, continentalbreakfasts,breakrefreshments,lunch,andawelcomereception.

Although it is not Mayo School of Continuous Professional Development (CPD) policy to limit the number of registrants for a course, conference room facilities may necessitate closing of enrollment; therefore, early registration is advised. Enrollment for this program is limited.

Foradditionalinformation,contact:Continuing Education200FirstStreetSW–Gonda6-472Rochester, MN 55905

E-mail: rstdomcme@mayo.eduPhone: 800-283-6296 or 507-266-6703Website: http://www.mayo.edu/cme/nephrologyupdate2013

Cancellation PolicyIf you cancel your participation in this course, your registration fee, less a $75 administrative fee, will be refunded when written notification is received by Mayo Clinic before Friday, September 6, 2013 (rstdomcme@mayo.edu or fax#: 507-266-7403). No refunds will be made on or after Friday, September 6, 2013. Canceled registrations are non-transferable.

Mayo School of CPD reserves the right to cancel or postpone any course due to unforeseencircumstances.IntheunlikelyeventMayoSchoolofCPDmustcancel or postpone this course, Mayo School of CPD will refund the registration fee but is not responsible for any related costs, charges, or expenses to participants, including fees assessed by airline/travel/lodging agencies.

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