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Article: 2670 Topic: 40 - Bipolar Disorders COMORBID BIPOLAR DISORDER AND BORDERLINE PERSONALITY DISORDER AND HISTORY OF SUICIDE ATTEMPTS M. Zimmerman Rhode Island Hospital, Brown Medical School, Providence, RI, USA Background: Both bipolar disorder and borderline personality disorder are associated with elevated rates of completed and attempted suicid e. No studies have examin ed whether there is an additive risk for suicida l behavi or in patien ts diagnosed wit h both disorders. In the present report from the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project we tested the hypothesis that patients diagnosed with both bipolar disorder and borderline personality disorder would have a higher rate of suicide attempts than patient s with either diagno sis alone. Methods: Three thousand four hundred and sixty-five psychiatric outpatients were interviewed with semi-structured interviews. Results: The suicide attempt rate in both the bipolar disorder and borderline personality disorder groups was significantly higher than the rate in patient s without either of these disorders . Compa red to the bipolar patients witho ut borderline personality disorder, the patients diagnosed with both bipolar and borderline personality disorder were significantly more likely to have made a prior suicide attempt (58.0% vs. 28.9%, p< .001) and to have made multiple suicide attemp ts (33.3% vs. 16.5%, p< .01). The patients with borderline personality disorder and bipolar disorder were nonsignificantly more likely than the border line patient s without bipolar disord er to have made a prior suicide attempt (58.0% vs. 46.7%, p=n.s.) and to have made multiple suicide attempts (33.3% vs. 24.2%, p=n.s.) Conclusions: While bipolar disorder and borderline perso nality disord er are each risk factors for suicida l behavi or, the co- occurrence of these disorders confers an additive risk.
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Transcript of 1-s2.0-S0924933813772948
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Article: 2670Topic: 40 - Bipolar Disorders
COMORBID BIPOLAR DISORDER AND BORDERLINE PERSONALITY DISORDER AND HISTORYOF SUICIDE ATTEMPTS
M. Zimmerman
Rhode Island Hospital, Brown Medical School, Providence, RI, USA
Background: Both bipolar disorder and borderline personality disorder are associated with elevated rates of completed andattempted suicide. No studies have examined whether there is an additive risk for suicidal behavior in patients diagnosed withboth disorders. In the present report from the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS)project we tested the hypothesis that patients diagnosed with both bipolar disorder and borderline personality disorder wouldhave a higher rate of suicide attempts than patients with either diagnosis alone. Methods: Three thousand four hundred and sixty-five psychiatric outpatients were interviewed with semi-structured interviews. Results: The suicide attempt rate in both the bipolar disorder and borderline personality disorder groups was significantlyhigher than the rate in patients without either of these disorders. Compared to the bipolar patients without borderlinepersonality disorder, the patients diagnosed with both bipolar and borderline personality disorder were significantly more likelyto have made a prior suicide attempt (58.0% vs. 28.9%, p< .001) and to have made multiple suicide attempts (33.3% vs.16.5%, p< .01). The patients with borderline personality disorder and bipolar disorder were nonsignificantly more likely than theborderline patients without bipolar disorder to have made a prior suicide attempt (58.0% vs. 46.7%, p=n.s.) and to have mademultiple suicide attempts (33.3% vs. 24.2%, p=n.s.) Conclusions: While bipolar disorder and borderline personality disorder are each risk factors for suicidal behavior, the co-occurrence of these disorders confers an additive risk.
