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OPTICAL QUALITY OF DUAL-OPTIC ACCOMMODATING INTRAOCULAR LENS

Andrea Galvis, MD 1,3 a

Ivan Ossma, MD MPH MSc 1,2, a

Sanjeev Kasthurirangan, PhD 4, b

1 Fundacion Valle del Lili, Cali-Colombia

2 Universidad Industrial de Santander, Bucaramanga-Colombia

3 Universidad Autonoma de Bucaramanga, Bucaramanga-Colombia

4 Abbott Medical Optics Inc, Irvine, USA

Financial Disclosure

a Consultant Abbott Medical Optics

b Scientist at Abbott Medical Optics Inc.

The Synchrony IOL is not currently FDA-approved

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Synchrony Design

Anterior Optic 32 Diopters

Posterior Optic Divergent (negative)

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+ Compare Optical Quality Pseudophakic Eyes

+ Monofocal IOL

+ Synchrony Dual Optic Accommodating IOL

+ Parameters

+ Objective iTrace aberrometry

+ Custom Matlab Software to calculate MTF

+ Subjective Contrast Sensitivity Testing

+ Optec 6500

Study Purpose

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Study Population

iTrace aberrometry

Cycloplegia

3 mm zone

Matlab Software to calculate MTF

Monofocal IOL : 15 subjects (30 eyes)

Synchrony IOL : 16 subjects (32 eyes)

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iTrace - Matlab conversion

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Results

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Objective Measurements3 mm pupil

Difference 0.01 um

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Best-focus MTF 3 mm pupil

Differences are less than 10%

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Mesopic Contrast Sensitivity

p=0.61 Wilcoxon Rank Sum Test

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Dual Optic Design DOES NOT affect optical or retinal image quality of the eye

Objective evidence (iTrace, MTF)

Subjective evidence (CSF)

Contrast sensitivity of Synchrony is equivalent to that of monofocal IOLs

Discussion

11Discussion

Effect of the slight spherical aberration on Synchrony would only yield 0.42 D of increased depth of focus

Calculations based on Rocha’s work *

The improved near vision of Synchrony patients MOST LIKELY due to true accommodation

* Rocha KM. Using Adaptive Optics Simultion to Explore the Effect of Higher Order Aberrations on Depth of Focus for the Correction of Presbyopia. Wavefront Congress 2008

12Conclusion

Quality of Vision of Synchrony IOL similar to standard monofocal IOLs

Measured Subjectively

Measured Objectively

Improved Near Vision with Synchrony

Not related to increased depth of focus