1

Normalized Curation

12 March 2009

Agenda 1/1 2

Agenda

• Foundation of normalized curation• Normalized curation• Pros and cons of normalized curation

Foundation of Normalized Curation 1/10 3

What is Normalized Curation?

• Normalized curation is a caDSR recommended technique used to minimize the number of CDEs needed for list or tabular data.

• CDEs are used to represent the data columns rather than the rows.

Foundation of Normalized Curation 2/10 4

Normalized Curation is Based on Existing Curation Techniques

• Multiples• 1 database field mapping to multiple CDEs

Foundation of Normalized Curation 3/10 5

Multiples Form 2900 Question 4

Foundation of Normalized Curation 4/10 6

MultiplesIllustration of the mapping

FormsNetcaDSR

cod_contrib

cod_specify

Contributing Cause of Death Type

Contributing Cause of Death Specify

Foundation of Normalized Curation 5/10 7

MultiplesForm Builder Report

Foundation of Normalized Curation 6/10 8

MultiplesTranslation of sample data

FormsNetcaDSR

cod_contrib = other infection

cod_specify = viral infection2

Contributing Cause of Death Type = other infection

Contributing Cause of Death Specify = viral infection2

Repeatsequence # Repeat

sequence #

1 Contributing Cause of Death Type = accidental death 1cod_contrib = accidental death

3Contributing Cause of Death Type = other organ failure

Contributing Cause of Death Specify = renal failure

cod_contrib = other organ failure

cod_specify = renal failure3

Foundation of Normalized Curation 7/10 9

1 FN Field Maps to 2 CDEsForm 2400 Questions 34 & 35

Foundation of Normalized Curation 8/10 10

1 FN Field Maps to 2 CDEsIllustration of the mapping

FormsNet caDSR

karn_lan_cde

Karnofsky Performance Status Score

karn_ln_score

Status Functional Scale Type

Lansky Performance Status Score

karn_lan_cde

Foundation of Normalized Curation 9/10 11

1 FN Field Maps to 2 CDEsForm Builder Report

Foundation of Normalized Curation 10/10 12

1 FN Field Maps to 2 CDEsTranslation of sample data

FormsNet caDSR

karn_lan_cde = karnofsky

Karnofsky Performance Status Score = 80karn_ln_score = 80

Status Functional Scale Type = karnofsky

Patient 1

karn_lan_cde = lansky

Lansky Performance Status Score = 60karn_ln_score = 60

Patient 2

Status Functional Scale Type = lansky

Normalized Curation 1/8 13

Normalized Curation ExampleForm 2400 Questions 438-449

Normalized Curation 2/8 14

Normalized Curation Example Non-Normalized Curation

• Wegener Granulomatosis Pulmonary Involvement Indicator– Permissible Values: Yes, No

• Wegener Granulomatosis Pulmonary Involvement Primary Transplantation Reason Indicator– Permissible Values: Yes, No

• Wegner Granulomatosis Renal Involvement Indicator– Permissible Values: Yes, No

• Wegner Granulomatosis Renal Involvement Primary Transplantation Reason Indicator– Permissible Values: Yes, No

Normalized Curation 3/8 15

Normalized Curation ExampleForm 2400 Questions 438-449

Normalized Curation 4/8 16

Normalized Curation Example Normalized Curation

• Wegener Granulomatosis Involvement Type– Permissible Values: Upper respiratory tract, pulmonary,

renal etc.• Wegener Granulomatosis Involvement Occurrence

Indicator– Permissible Values: Yes, No

• Wegener Granulomatosis Involvement Primary Transplantation Reason Indicator– Permissible Values: Yes, No

• Wegener Granulomatosis Involvement Specify – Free Text

Normalized Curation 5/8 17

Normalized Curation Example Illustration of the mapping

caDSR FormsNetWegener Granulomatosis Involvement Type

Wegener Granulomatosis Involvement Occurrence Indicator

pre_ted_wg_up_rsp_yn

pre_ted_wg_pulm_yn

pre_ted_wg_renal_yn

pre_ted_wg_renal_typeWegener Granulomatosis Involvement Type

Wegener Granulomatosis Involvement Specify

Etc.

pre_ted_wg_other_spec

Normalized Curation 6/8 18

Normalized Curation ExampleForm Builder Report

Normalized Curation 7/8 19

Normalized Curation ExampleForm 2400 Questions 438-449

Normalized Curation 8/8 20

Normalized Curation Example Translation of sample data

FormsNet

pre_ted_wg_other_yn = yes

2

caDSR

W G Involvement Type = other

WG Involvement Occurrence = yes2

Repeat sequence #

Repeat sequence #

WG Involvement Transplantation = yespre_ted_wg_other_hsct_yn = yes

pre_ted_wg_other_spec= cardiacWG Involvement Specify = cardiac

pre_ted_wg_skin_yn= no1

W G Involvement Type = skin

WG Involvement Occurrence = no1

Pros and Cons of Normalized Curation 1/2 21

Pros and Cons of Normalized Curation

• Pros– More generic CDEs have greater reuse potential– Fewer CDEs are created– Easier to aggregate data

• Cons– AGNIS captures data differently than FormsNet– Legacy systems may make normalized translations

difficult– Not all tabular or list data can be normalized

Pros and Cons of Normalized Curation 2/2 22

Not All Tabular / List Data Can Be NormalizedForms 2006: 61-70, 2100: 649-658, 2200: 591-600, 2300: 290-299