Welcome To

Microbiology and Immunology 2100A Biology of Prokaryotes

2012

Information Flow

OWL site

access via https://owl.uwo.ca

For assistance with OWL, contact the ITS Computer Support Centre

By Webform:

http://itshelp.uwo.ca

By Phone:

519-661-3800

In Person:

main floor right inside the front doors of the Support Services Building

OWL Course Tools

Home

Announcements

Syllabus (Course outline and information)

Schedule (Calendar)

Messages

OWL Course Tools

Lectures

Lab information

Lab Reports

Prelab Talks

Lectures will be in pdf format or Power Point

presentations

Course Schedule

Lectures

Monday and Wednesday 11:30 am – 12:20 pm

WSC 55

Laboratories

Tuesday, Wednesday or Thursday

2:30 to 5:30 pm

Medical Sciences Building (MSB) 120

weekly

Instructors

Dr. Susan Koval, Course Coordinator

Dental Science Building 3013A

Tel: 519-661-3439

Dr. Carole Creuzenet

Dr. Tom Linn

Instructors are available via OWL messages,

or by appointment

Sources of Wisdom

Instructors

Textbook

Brock Biology of Microorganisms, by M.T. Madigan, J.M. Martinko, D.A. Stahl and D.P. Clark. 13th edition. 2012 Benjamin Cummings

2 copies in the Taylor Library on 2 h reserve

Lab Manual

Microbiology: Laboratory Theory and Application, Brief, 2nd edition, M.J. Leboffe and B.E. Pierce, Morton Publishing, 2012.

Additional microbiology textbooks, for use in

writing lab reports, are on 2 h reserve in the

Taylor library

Course readings will be assigned from the

textbook by each instructor

The readings expand the concepts discussed in

the lectures

Evaluation

Component % of Final Mark

Midterm test 25

Laboratory 30

Final exam 45

Midterm test: Friday October 26, 2012, 7:30 to 9

pm in Labatt Health Sciences Building, room 40

Format of exams

Midterm test and final exam will consist of

multiple choice questions from lectures and

assigned readings

Course work for the midterm test includes

lectures to the end of the ‘Metabolism’ section

Final exam will be cumulative, with emphasis on

the second half of the course

Deadlines and Ethical Issues

Described in detail in the Syllabus

Absence from tests and exams

Absence from laboratory periods

Very important to read!

Course Strategies/Philosophy

MicroImm 2100A is an entry-level course in

bacteriology

it provides background information for advanced

courses, and thus will encompass details as well

as concepts

assumes a fundamental working knowledge of

biology and developing concepts of biochemistry

Our Responsibilities and Expectations

Teach the fundamental concepts of bacteriology via lectures and laboratories

Be available for consultation

We expect students to

Attend lectures and laboratories

Come prepared

Do the course readings

Work hard

instructors are aware that many students in this course have a variety of career goals in mind. Skills acquired in this course can be used in other settings, not just in a microbiology environment

Your Responsibilities and Expectations

?

Laboratory Schedule

Laboratories are weekly

No laboratory practical the week of September

10th – time will be used to discuss topics related

to microbiology labs: biosafety and the writing of

laboratory reports

Attendance is noted, as is punctuality

Reserve the three hour time slot in your

schedule

Laboratory Session – week of September 10

MSB 120 at 2:30 pm

the following topics will be discussed

Laboratory procedures and safety rules

Biosafety

Biohazards

Guidelines for writing laboratory reports

Please READ these two files:

Laboratory Guidelines

Guidelines for Writing Laboratory Reports

Course Description in the Academic

Calendar

This course examines the fundamental aspects

of the structure, physiology, genetics and

phylogenetic relationships of the Bacteria and

Archaea. Examples of medically and

environmentally important organisms are

presented.

Relevance of microbes to health, industry and

the environment

Borrelia burgdorferi Legionella pneumophila

Pathways of Discovery in

Microbiology

Dr Susan Koval’s concept map for 2100A

The prokaryotic

cell: structure

and function

Taxonomy: who are we looking at?

Environmental effects on growth:

Some like it hot, some

don’t !

Lectures by Drs.

Creuzenet and Linn

Metabolism: how do

prokaryotes generate energy?

Dr Tom LINN’s concept map for 2100A

BACTERIAL GROWTH

Cell Division

Bacterial Population

Growth

Control of Bacterial Growth

Bacterial Empire Strikes

Back

(Drug Resistance)

GENE EXPRESSION

Transcription of Bacterial Genes

Basic Mechanisms of Regulating Transcription

Genomics (Genes, RNA, Proteins, Metabolites, Interactions on an Organism Scale)

Dr Carole CREUZENET’s concept map for 2100A

Transfer of virulence traits

Shaping evolution Concepts/mechanisms

Origin of toxins/virulence

features

Bacterial genetics Food- and water- borne

bacterial diseases

Mechanisms of gene

transfer/mutations Bacterial pathogens and

associated diseases

R.R. Colwell (Past President of the American Society for

Microbiology)

“Microorganisms are what keeps life going on the planet.

There needs to be an understanding that

microorganisms are not just pathogens. For every

pathogen, there are large numbers of microorganisms

carrying out protective activities that keep the cycle of

nature going".

From: The Microbial World: Foundation of the

Biosphere. 1997. American Academy of Microbiology

Enjoy the course!