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    Correlating

    Neuroanatomywith PatientPresentation

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    Supratentoria Infratentorial

    SupportStructures

    Pathways

    Overview of the Nervous System

    above tentorium cerebelli - which contains the cerebrum

    below - which contains

    the cerebellum

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    Tentorium

    Cerebelli

    Supratentorial

    CorticalSubcortical

    Infratentorial

    BrainstemCerebellum

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    Cortical

    Outer gray matterLocation of cell bodies (neurons, glia)

    SubcorticalWhite matter (includes the internal

    capsule)Highways that connect cellbodies (axons)

    Deep nuclei: gray matterBasal Ganglia motor control

    Thalamus sensory, motor,consciousness

    Hypothalamus homeostasis

    Supratentorial

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    Cerebral Cortex: 5 lobes: function1. Frontal:2. Parietal:3. Occipital:4. Temporal:5. Insula:

    **GOOD QUIZ QUESTION

    **

    movement, decision making, higher lvl of thinking, motion and personality

    sensory

    vision

    auditory, speech, language, memory, emotion

    limbic response

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    Neuroanatomy: Infratentorial

    Brainstem: 3 areasMidbrainPons

    Medulla

    Neuroanatomy: InfratentorialCranial nervesCenters for eye movementCardiac, respiratory centers

    autonomic: respiratory, HR, BP

    relay station

    vision, hearing, motor control, sleep/wake,

    arousal/alertness, temp control

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    Cerebellum:Lobes, Hemispheres, Tonsils

    Functional divisions

    Midline (vermis)-

    Lateral hemispheres-

    Neuroanatomy: Infratentorial

    coordination and balance

    axial coordination

    (limb coordination)

    most important for motor control

    (of gait)

    ant, post, and flocculonodular lobe

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    Conduit for motor and sensorypathways

    Lateral corticospinal tract (LCST) Upper motor neuron axons

    Dorsal columns (DC)

    Antero-lateral system (ALS)

    Pain/temperature Anterior horn cells ( motor neuron)

    Lower motor neuron cell bodies

    Proprioception, discriminative touch and vibration

    contralateral

    limbs

    signals coming from cerebral

    cortex to brainstem

    SENSORY PATHWAY

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    DC

    LCST

    ALSAlpha

    LE

    UE

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    Ends at

    Cauda equina-..Nerve roots continue to exitrespective intervertebral foramen

    C2-7: above respectivevertebra

    C8: between C7-T1

    T, L, S roots below

    conus medullaris (L1-L2)

    (L2-L5)

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    Neuroanatomy: Support structures

    Meninges

    SpacesVentricles

    Cerebrospinal FluidBloodArterialVenous

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    Neuroanatomy: Support structures

    Meninges

    (outside-in)EPIDURAL

    1. Dura MaterSUBDURAL

    2. Arachnoid MaterSUBARACHNOID

    3. Pia Mater

    Venous blood: tornbridging vein

    Normally containscerebrospinal fluid

    (CSF)Arterial blood:aneurysm rupture

    Arterial blood: tornmeningeal artery

    (outer most)

    When patient has hydrocephalus: monitor CSF

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    Epidural space

    A potential space inthe cranium

    A real space in the

    vertebral canal

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    Neuroanatomy: Support structures

    Ventricular system

    Cerebrospinal fluid (CSF)direction of flow inventricular system:

    Lateral ventricles (2) Interventricular foramen of

    Monro (2)

    Third ventricle (1)Cerebral aqueduct (1)

    Fourth ventricle (1)3 foramen

    Subarachnoid space (SAS)Intraventricularhemorrhagevs. subarachnoidhemorrhage

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    Neuroanatomy: Support structuresVentricular system: CSF resorption

    Arachnoid villi/granulations

    Project from the SASinto the sinuses

    Cerebral venous sinusesimportant for drainage

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    Neuroanatomy: Support structures

    Anterior Circulation 2 Carotid Arteries

    Posterior Circulation 2 Vertebral Arteries

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    Vascular Supply

    MCA - MOST common CVA location

    ACA

    PCA

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    Neuroanatomy: Support structures

    Blood SupplyAnterior Circulation

    Carotid Arteries (2)

    Ophthalmic artery

    Posterior communicating artery

    Pcomm

    Anterior choroidal artery

    Anterior cerebral artery (ACA)

    Middle cerebral artery (MCA

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    Neuroanatomy: Support structures

    Blood Supply

    Posterior CirculationVertebral Arteries (2)Posterior Inferior Cerebellar

    (2 - PICA)Anterior Spinal Artery (1 -

    ASA)

    Basilar Artery (BA)Anterior Inferior Cerebellar(2 -AICA)

    Superior Cerebellar (2 -SCA)

    Posterior Cerebral (2 -PCA)

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    Neuroanatomy: Support structures

    Blood supplyArterialThe Cerebral arteries (anterior, middle,

    posterior) are terminal branches

    Numbered segments (first, second, third

    order branches)i.e. A1, A2, A3, or M1, M2, M3, or P1, P2, P3

    The internal carotid also has segmentsCervical, carotid siphon, supraclinoid

    (intracranial)

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    Neuroanatomy: Support structures

    VenousSinusesVein of Galen

    IGNORE THIS SLIDE

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    Three that are important to our patients!

    1. Lateral Corticospinal TractVolitional movement, the upper motor neuron

    2. Dorsal Column Medial Lemniscus SystemAKA large fiberProprioception/kinesthesia, discriminative touch,vibration

    3. Spinothalamic Tract / Antero-lateral systemAKA small fiberPain, temperature, crude touch, itch, tickle

    What are the differences in: pathways?

    modalities?

    originates in spinal cord and travels up and transmits info

    to thalamus

    crosses over at cervico-medullary

    junction

    crosses over at spinal segment

    DESCENDING

    ASCENDING

    ASCENDING

    crosses over at spinal segment

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    What is the name of the 1o efferent track in the SC?What cells in the CNS give rise to this efferent track?What is the other name for these cells / track?What is the name for the analogous track for the CN?

    Spinal Cord

    lateral corticospinal tract

    pyramidal cells

    cross-pyramidal (OR lateral cerebrospinal tract)

    subcortical bulbar tract

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    Somatosensory / Proprioceptive Input

    crosses over at the level of spinal

    segment

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    Somatosensory / Proprioceptive Input

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    Anterior horn cell / lowermotor neuron pathology:LMN

    Hemi-cord pathologyaffects touch andvolitional movement on

    Lateral brainstempathology often affects.

    Medial brainstempathology often affects.

    ThalamusInfarcts usually affectOnly.

    Internal CapsuleInfarcts affect

    Pain, Touch,Volitionalmovement isperceived/controlled by.IGNORE THIS SLIDE

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    Distribution of Sensory Impairment1. 2. 3. 4.

    a. Dermatomalb. Hemisphericc. Polyneuropathyd. Segmental

    dermatomal

    hempisphericpolyneuropathy

    involves many nerves at a time - both motor and sensory