1 Chapter 23 and 24 Valvular problems and circulatory shock.
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Transcript of 1 Chapter 23 and 24 Valvular problems and circulatory shock.
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Chapter 23 and 24Valvular problems and circulatory shock
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Terms
Prolapse- valve doesn’t close properly
Stenosis- valve has difficulty opening (can have problem with closing too).
Regurgitation- backflow of blood
Auscultation- “listening” to heart sounds….more of them when valves don’t work correctly.
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Dynamics of Streptococcal Damage to Heart Valves Streptococcus
release of M antigen
MM
MM
Heart valve cellwith M antigensattached
• Antibody formed against combination
• Complement damage to heart valves
Mitral #1Aortic #2
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Dynamics of mitral stenosis Stenosis: blood flow from
left atrium to left ventricle decreased
Murmur heard in last part of diastole- why?
Reduced movement of blood.
Enlarged left atrium. Pulmonary edema.
MAP
C.O.
L.ATRIAL VOL. and pressure
RT. VENT. PRESS.
Pulmonary edema
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Mitral valve prolapse
Blood goes back into left atrium
Blowing murmur heard throughout systole - high pitch
MAP and C.O.
MEAN L.ATRIAL VOL.And Pressure Pulmonary edema
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Dynamics of Aortic valve Stenosis Stenosis: Contracting left ventricle
fails to empty adequately (ESV?) SV decreased Left ventricle hypertrophy Leads to increased blood volume
(due to decreased MAP)—kidneys release erythropoietin.
L. Vent pressure and volume
MAP and C.O.
Left atrial pressure Pulmonary edema
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Aortic Regurgitation
Murmur heard during diastole
May have stroke vol. of 300ml with 70ml going to periphery and 230 leaking back
Left ventricular vol and pressure
MAP and net C.O.
Left atrial pressure Pulmonary edema
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Circulatory SHOCK
1. Hypovolemic
2. Vascular
3. Cardiogenic
Circulatory shock-generalized inadequate blood flow to the bodyProgressive vs. non-progressive shock
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Hemorrhage
Diarrhea
Vomiting
Large-scale Fluid Loss
Hypovolemic Shock
• Rapid weak pulse
• Cold, clammy skin
• Decreased CO
• Kidneys respond with angiotensin
• ADH
WHY???
Hint: baroreceptor reflex arc
Burns
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Excessive Allergic Response
Massive Histamine Release
Extreme Vasodilation
Anaphylactic Shock
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Failure to maintain vasomotor tone.
Excess vasodilation.
Neurogenic Shock
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Infection with Gram Negative Bacteria
Bacteria Release Endotoxin
Immune Cells Respond by Releasing Huge Amounts of Vasodilating Nitric Oxide
Excess Vasodilation
Septic Shock
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Inability of the heart to efficiently pump blood.
Cardiogenic Shock
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Hypertension vs. Hypotension
Hypertension MAP is greater than 110mmHg Remember that normal is about
96mmHg Remember how to calculate
MAP? Excess workload, excess
pressure (damage to brain and kidneys)
Treat: diet, exercise, diuretics, Beta-blockers (what does this do to HR?), calcium antagonists (inotropy?), ACE inhibitors
Hypotension CO doesn’t maintain
perfusion Can result from neurogenic
shock Low plasma volume
(excessive sweating, urination, or decreased water intake)
Treat with more salt and water intake.
Note for lab test: be able to calculate PP, MAP, and understand distensibility and hyper/hypotension if given blood pressure values.