03-05 W. W. Norton 02-11ab 02-28 02-29 Adapted from Kandel, E.R. Schwartz, J.H., and Jessell, T.M....
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Transcript of 03-05 W. W. Norton 02-11ab 02-28 02-29 Adapted from Kandel, E.R. Schwartz, J.H., and Jessell, T.M....
![Page 1: 03-05 W. W. Norton 02-11ab 02-28 02-29 Adapted from Kandel, E.R. Schwartz, J.H., and Jessell, T.M. (Eds.), Principles of Neural Science, 3rd.](https://reader035.fdocuments.in/reader035/viewer/2022070413/5697bfea1a28abf838cb75bd/html5/thumbnails/1.jpg)
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W. W. Norton
![Page 3: 03-05 W. W. Norton 02-11ab 02-28 02-29 Adapted from Kandel, E.R. Schwartz, J.H., and Jessell, T.M. (Eds.), Principles of Neural Science, 3rd.](https://reader035.fdocuments.in/reader035/viewer/2022070413/5697bfea1a28abf838cb75bd/html5/thumbnails/3.jpg)
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W. W. Norton
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W. W. Norton
![Page 8: 03-05 W. W. Norton 02-11ab 02-28 02-29 Adapted from Kandel, E.R. Schwartz, J.H., and Jessell, T.M. (Eds.), Principles of Neural Science, 3rd.](https://reader035.fdocuments.in/reader035/viewer/2022070413/5697bfea1a28abf838cb75bd/html5/thumbnails/8.jpg)
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Important Neurotransmitters
endorphinacetylcholinedopaminenorepinephrineserotoninGaba
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Endorphin
Relieves pain
Responsible for “joggers high”
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Acetylcholine
Important in memory
Transmitter in the hippocampus
Transmitter at the neuro-muscularjunction.
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Acetyl CoA + Choline
Acetylcholine
notes: Vitamin B5 makes up part of Acetyl CoA.
curare (a dart poison) blocks acetylcholine
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Dopamine
There is too little in Parkinson disease
There is too little in tardive dyskinesia
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Norepinephrine
There is too little in depression
Increases alertness
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Tyrosine
L-dopa
dopamine
norepinephrine
Phenylalanine
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W. W. Norton
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MAO = monoamine oxidase
MAO Breaks down:
dopaminenorepinephrineserotonin
An MAO inhibitor prevents the breakdownof these neurotransmitters.
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Serotonin
Controls sleep onset
There is too little in depression
Affected by the prescriptiondrugs prosac and zoloft
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tryptophan
serotonin
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GABAGABA
Valerian root affects GABA
GABA is available as afree from amino acid
Can act as a tranquilizer
Prescription