01 Introduction to Biochemsitry

8/2/2019 01 Introduction to Biochemsitry

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BIOCHEMISTRY

Geromil J. Lara, RMT,MSMT


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BIOCHEMISTRY

CREDIT: 5 units (3-2)

3 Hours Lecture

6 Hours Laboratory

Grading System

Lecture = 50% Laboratory = 50%


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BIOCHEMISTRY

Grading System

Lecture = 50%

Quizzes = 50%

Long Exam = 50%

Laboratory = 50%

Quizzes = 50% Written Exam = 50%


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BIOCHEMISTRY

Topic Outline

Midterm

Review of Micromolecules

The Living Cell

Proteins

Enzymes

Nucleic Acids


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BIOCHEMISTRY

Topic Outline

Finals

Carbohydrates

Vitamins

Lipids

Metabolisms


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BIOCHEMISTRY

Deals with the study of the chemistry of livingorganisms

Application of the principles and methods of

chemistry to the field of biology andphysiology

Concerned with the physico-chemicalprocesses underlying

Digestion, absorption, circulation, respiration,metabolism, growth, and reproduction


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BIOCHEMISTRY

Clinical Biochemistry

Physiological Chemistry

Normal processes

Pathological Chemistry

Abnormal processes


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BIOCHEMISTRY

is both a l i fe science and a chemicalscience

i t explores the chemistry of l iv ing

organisms and the molecular basis forthe changes occurr ing in l iv ing cel ls

has become the foundation forunderstanding al l biologicalprocesses

i t has provided explanations for thecauses of many diseases in humans,

animals and plants


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REVIEW OF BIOMOLECULES


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ORGANIC COMPOUNDS

2 General Classif icat ions

1. HYDROCARBONS

Conta in only carbon and hydrogen

ALIPATHIC HYDROCARBONS

N o b e n z e n e r i n g s o r a d e r i v a t i v e o f t h eb e n z e n e r i n g

A L K A N E S , A L K E N E S , A N D A L K Y N E S AROMATIC HYDROCARBONS

C o n t a i n a b e n z e n e r i n g o r a d e r i v a t i v e o ft h e b e n z e n e r i n g


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HYDROCARBONS

ALIPATHIC

Saturatedcontain single

C-H bond

Alkanescontain onlysingle bond

(ethane)

Unsaturatedcontain 2 or

more C-H bond

Alkenescontain at least

one doublebond (ethene)

Alkynescontain at leastone triple bond

(ethyne)

AROMATIC


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ORGANIC COMPOUNDS

General Classif icat ions

2. Subst i tuted Hydrocarbons

Which one or more hydrogen atoms is

replaced by another a tom or group ofa toms

Funct iona l group

I s an a tom or group of a toms ar ranged

in a pa r t i c u la r wa y tha t i s p r im a r i l yr e s pons ib le fo r the c he m ic a l a ndphy s ic a l p r ope r t i e s o f the m ole c u le inwh ic h i t i s found


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HYDROPHOBICITY vs. HYDROPHILICITY

HYDROPHOBIC

Refers to thephysical property of

a molecule that isrepelled from a massof water

Alkanes, oils, andfats

HYDROPHILIC

Refers to a physicalproperty of a

molecule that cantransiently bond withwater (H2O) throughhydrogen bonding


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CHEMICAL BONDS

2 PrincipalClasses

1. Ionic Bonding

Involves at ransfer o f oneor moree lec t rons f romone a tom toanother ,lead ing to theformat ion o f anion ic bond


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CHEMICAL BONDS

2 PrincipalClasses

2. Covalent

Bonding

Involves asharing pairs

of electronsbetweenatoms


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CHEMICAL BONDS

HydrogenBonding

Hydrogen atomis bonded to asmal l , highlyelectronegative

atom


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01 Introduction to Biochemsitry

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