0 BIOCERT, 2009 BIOTRONIK Training & Education Electrophysiology EP Studies in Bradyarrhythmias.

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1 BIOCERT, 2009 BIOTRONIK Training & Education Electrophysiology EP Studies in Bradyarrhythmias

Transcript of 0 BIOCERT, 2009 BIOTRONIK Training & Education Electrophysiology EP Studies in Bradyarrhythmias.

Page 1: 0 BIOCERT, 2009 BIOTRONIK Training & Education Electrophysiology EP Studies in Bradyarrhythmias.

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BIOTRONIK

Training & Education

Electrophysiology

EP Studies in Bradyarrhythmias

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EP Studies in Bradyarrhythmias

▍Sinus node functionality

▍AV node functionality

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Tests of Sinus Node Function

Sinus Node Recovery Time = SNRT

▍Test of intrinsic function

▍Atrial overdrive pacing (30 sec)

▍Time from last paced to first spontaneouscomplex after cessation of pacing in HRA

▍Varies with sinus rate, correction:CSNRT = SNRT – sinus cycle length

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Sinus Node Recovery Time

HRA = High Right Atrium

SCL = Sinus Cycle Length

SNRT = Sinus Node Recovery Time

Sinusnode

HRA

Murgatroyd, Krahn: Handbook of Cardiac Electrophysiology 2002

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Tests of Sinus Node Function

▍Repeated measurements at different cycle length

▍Longest values to be used

▍Normal: max SNRT <1500 msmax CSNRT <550 ms

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Sinus Node Recovery Time

CL = 930, S1S1 = 700, SNRT = 1175, CSNRT = 245 ms

Prior to start of pacing

End of 30-s pacing train

Murgatroyd, Krahn: Handbook of Cardiac Electrophysiology 2002

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EP Studies in Bradyarrhythmias

▍Sinus node functionality

▍AV node functionality

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Evaluation of AV Conduction with EP

First Degree AV Block

A

H

V

HBE

ECG

HV interval prolonged = distal block

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Evaluation of AV Conduction with EP

First Degree AV Block

AH

V

AH interval prolonged = block in AV node

HBE

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Evaluation of AV Conduction with EP

Second Degree AV Block Type Wenckebach

HBE

ECG

Gradual prolongation of AH interval before blocked beat,no exit from the AV node

A

HV

A

H

VA

180 210

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Evaluation of AV Conduction with EP

Second Degree AV Block Type Mobitz

HBE

▍Dropped beat after H spike

▍No prior prolongation in AH or HV intervals

▍Subnodal block

V VA A A

H HH?

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Evaluation of AV Conduction with EP

Third-Degree AV Block

HBE

Above: H prior to escape V, block in AV node

HBE

V V

V V V V

H H H H

A A A A A A AA

H

A A A A A A A

H H H H H

Below: H follows each A, distal block

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Atrial Extrastimulus Testing

▍Aim- Investigation of the dynamic properties of the conduction over the AV node and the His-Purkinje system- Refractory periods of AV node and right atrium

▍Method- Drive train of 5-8 atrial paces with fixed cycle length followed by an atrial extrastimulus- Progressive decrease of coupling interval until atrial non capture

▍Observations- Gross abnormalities of intra-atrial conduction - Presence of dual AV node physiology- Abnormal conduction structures (accessory pathways) - Arrhythmia induction

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Antegrade Conduction over AV Node

▍Long coupling intervals- fairly constant conduction

▍Shorter coupling intervals- increasing AH delay, HV constant

▍Progressively shorter- AV nodal block, atrial refractoriness

Atrial Extrastimuli

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Atrial Extrastimuli with Long Coupling

A1H1 ≈ A2H2

Murgatroyd, Krahn: Handbook of Cardiac Electrophysiology 2002

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Atrial Extrastimuli with Long Coupling

S1A1 ≈ S2A2 ≈ 55 ms, H1V1 ≈ H2V2 ≈ 50 msS1S1 = 500 ms, S1S2 = 400 ms

Murgatroyd, Krahn: Handbook of Cardiac Electrophysiology 2002

A1H1 = 78 ms, A2H2 = 97 ms

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Atrial Extrastimuli with Shorter Coupling

A1H1 < A2H2

Murgatroyd, Krahn: Handbook of Cardiac Electrophysiology 2002

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Atrial Extrastimuli with Shorter Coupling

Atrial escape: inverted P in aVF, earliest in CS*S1S1 = 500 ms, S1S2 = 300 ms H1V1 ≈ H2V2 ≈ 50 ms

Murgatroyd, Krahn: Handbook of Cardiac Electrophysiology 2002

A1H1 = 78 ms, A2H2 = 140 ms

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Atrial Extrastimuli Very Short Coupling

AV nodal refractoriness

Murgatroyd, Krahn: Handbook of Cardiac Electrophysiology 2002

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Atrial Extrastimuli Very Short Coupling

A1A2 = 280 ms, no His after A2 S1S1 = 500 ms, S1S2 = 280 ms

AV nodal effective refractory period (AVN-ERP): 280 ms

Murgatroyd, Krahn: Handbook of Cardiac Electrophysiology 2002

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AV Nodal Refractory Periods

▍Effective Refractory Period (AVN-ERP)- longest A1A2 interval on HBE that fails

to be conducted to the His bundle

- normal values: 250 – 400 ms

▍Functional Refractory Period (AVN-FRP) - shortest H1H2 interval that can be

elicited by any A1A2 interval

- normal: 330 – 550 ms

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Incremental Atrial Pacing

▍Method- Pacing at constant cycle length slightly shorter than

spontaneous rhythm

- Pacing cycle length decrease in small steps

- Analysis of rhythm for several seconds

at each step (steady-state)

▍Observations- Cycle length at which 1:1 conduction over the AV node ceases

( Wenckebach cycle length)

- Sudden increase in the AH interval

( dual AV nodal physiology)

- Ventricular pre-excitation ( accessory pathway)

- Arrhythmia induction

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Incremental Atrial Pacing

Wenckebach1:1 Conduction

WCL = Wenckebach Cycle Length

Murgatroyd, Krahn: Handbook of Cardiac Electrophysiology 2002

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Incremental Atrial Pacing

Murgatroyd, Krahn: Handbook of Cardiac Electrophysiology 2002

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BIOTRONIK

Training & Education

Electrophysiology

EP Studies in Bradyarrhythmias