Pic

oSu

re™

Changing dermatology forever

Unprecedented innovation

in laser technology.

PicoSure, the world’s first safe and effective

picosecond aesthetic laser, has arrived.

This unparalleled breakthrough in laser

technology delivers ultra-short pulse bursts

of energy to the skin in trillionths of a second.

Picosecond pulse width is 100 times shorter

than nanosecond technology, enabling

unmatched photomechanical impact for

better clearance with fewer treatments.

The future is here.

PicoSureChanging dermatology forever

Employment

concerns cited by

40% as reason for

tattoo removal5

32% increase of

tattoo removal

procedures in 20114

(by aesthetic physicians)

m i l l i o n

20%

regret factor3

• Female ~ 69% • College educated

• Single • 24-39 years old

Typical American tattoo patient1:

45 mi l l ion 2

32%growth

Shattering the past. Revealing the future.

PicoSure is the first and only aesthetic

picosecond laser for the safe and

effective removal of tattoos and

benign pigmented lesions.

PicoSure’s ultra-short pulse duration goes

beyond photothermal action creating an

intense photomechanical impact, patented

PressureWave™, resulting in greater disruption

of the target for better clearance with fewer

treatments, less fluence and without injury to

the surrounding skin. Even dark, stubborn blue

and green inks, as well as previously-treated,

recalcitrant tattoos can be removed.

Picosecond vs. nanosecond technology

Traditional nanosecond lasers predominately rely on photothermal action, delivering heat to the pigment and surrounding tissue.

PicoSure takes advantage of PressureWave Technology to shatter the target ink into tiny particles that are easily eliminated by the body.

Ultra-short Pulse Duration Is the Difference

• Picosecond pulse width is 100X shorter than nanosecond technology.

• only ultrashort pulse durations trigger photomechanical effect.

• With this short pulse width, half the fluence is required

compared to Q-Switched nanosecond lasers.

PICOSURE LASER

UNTREATED INK

TRADITIONAL LASER

Q-Switched

Picosecond

TATTOO BEFORE AFTER 1 MONTH, 3 TX

Electron Microscopy images courtesy of H.R. Jalian, M.D.

Photos courtesy of Cynosure, Inc.

laser response comparison

AFTER 20 Tx Q-SWITCHED Nd:YAG AFTER 6 Tx PICOSURETATTOO BEFORE

Clinical data shows

better results in fewer treatments, even with recalcitrant tattoos6.

Photos courtesy of Cynosure, Inc.

Photos courtesy of Roy G. Geronemus, MDPhotos courtesy of Roy G. Geronemus, MD

Recalcitrant tattoo

PIGMENTED LESION BEFORE AFTER 1 Tx PICOSURE TATTOO BEFORE AFTER 3 Tx PICOSURE

REFERENCES:

1. http://esciencenews.com/articles/2008/07/21/study.examines.motivations.tattoo.removal

2. Harris interactive, 2012

3. Harris interactive, 2013

4. Patient’s Guide survey, published may 22, 2012, http://blog.patientsguide.com/2012/05/study-tattoo-removal-climbs-32-in-competitive-job-market/

5. ABC news, may 2012

For the power of PicoSure contact your Cynosure consultant today.Call 800-886-2966. Visit www.picosure.com

General Specifications

nominal Wavelength 755nm

Pulse Duration 750ps

Pulse Energy 200mJ

Electrical Power 200-240 V~,4.5 kVA, 50/60Hz, single phase

Electrical Service Requirement 30Amp

Handpiece Specifications

Zoom Handpiece

Spot Size 2.0–6.0mm

Fixed Handpieces

Spot Size 6.0, 8.0, 10.0mm

SOLID STATE LASERPulse Energy: 200mJPulse Width: ≤ 900psWavelength: 755nm

Maximum Power: <5mWWavelength: 630–690nm CW

INVISIBLE LASER RADIATIONAVOID EYE OR SKIN EXPOSURE TODIRECT OR SCATTERED RADIATION.

EN 60825-1: 2007 CLASS 4 LASER PRODUCT

AIM LASER CLASS–3R

6. Successful and Rapid Treatment of Blue and Green Tattoo Pigment With a novel Picosecond laser, Jeremy A. Brauer, mD; Kavitha K. Reddy, mD; Robert Anolik, mD; Elliot T. Weiss, mD; Julie K. Karen, mD; Elizabeth K. Hale, mD; lori A. Brightman, mD; leonard Bernstein, mD; Roy G. Geronemus, mD

© 2013 Cynosure, inc. Cynosure is a registered trademark and PicoSure is a trademark of Cynosure, inc. PicoSure and PressureWave are trademarks of Cynosure, inc. 921-0415-000 Rev. 1 02/13